November 7, 2016
Frank Slack to present Division of Biology Seminar Nov. 18
Submitted by Division of Biology
Frank Slack, BIDMC/Harvard Medical School, will present "MicroRNA-based therapeutics in 1xbet sports betting " as a high profile speaker for the Division of Biology Seminar Series at 4 p.m. Friday, Nov. 18, in the Town Hall of the Leadership Studies Building.
The abstract for the lecture is derived fromMicroRNAs, small non-coding RNAs that regulate gene expression to control important aspects of development and metabolism such as cell differentiation, apoptosis and lifespan. miR-21, miR-155, let-7 and miR-34 are microRNAs implicated in human 1xbet sports betting . Specifically, human let-7 and miR-34 are poorly expressed or deleted in lung 1xbet sports betting , and over-expression of let-7 or miR-34 in lung 1xbet sports betting cells inhibits their growth, demonstrating a role for these miRNAs as tumor suppressors in lung tissue. let-7 and miR-34 regulate the expression of important oncogenes implicated in lung 1xbet sports betting , suggesting a mechanism for their involvement in 1xbet sports betting . Slack is focused on the role of these genes in regulating proto-oncogene expression during development and 1xbet sports betting , and on using miRNAs to suppress tumorigenesis. In contrast, miR-21 and miR-155 are oncomiRs and up-regulated in many 1xbet sports betting types. He is also developing effective strategies to target these miRNAs as a novel anti-1xbet sports betting approach. Lastly he is examining the non-coding portions of the genome for mutations and variants that are likely to impact the 1xbet sports betting phenotype. Dr. Slack has successfully resequenced the 3’UTRome and microRNAome from 1xbet sports betting patients with a family history of 1xbet sports betting .
If you would like to visit with Slack, contact Anna Zinovyeva at zinovyeva@1xbet sports betting edu. Slack’s visit is co-sponsored by the Division of Biology and the 1xbet sports betting Office for the Advancement of Women in Science and Engineering, orKAWSE, through the ADVANCE Distinguished Lecture Series.