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2.853846 0 Td 26.923077 Tz (, ) Tj 0.412821 0 Td 67.307692 Tz (KS ) Tj 61.428571 0 0 61.428571 0 2272.006 Tm 9.734884 0 Td 27.131783 Tz (\( ) Tj 0.17907 0 Td 62.403101 Tz (US ) Tj 0.797674 0 Td 27.131783 Tz (\) ) Tj 0.227907 0 Td 13.565891 Tz (; ) Tj 0.34186 0 Td 49.612403 Tz (Michael ) Tj 2.295349 0 Td 56.637597 Tz (Pumphrey ) Tj 2.751163 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 48.062016 Tz (Pullman ) Tj 2.051163 0 Td 13.565891 Tz (, ) Tj 57.142857 0 0 57.142857 0 2229 Tm 10.4475 0 Td 84.583333 Tz (WA ) Tj 1.225 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 67.083333 Tz (US ) Tj 0.84 0 Td 29.166667 Tz (\) ) Tj 0.2625 0 Td 14.583333 Tz (; ) Tj 0.3675 0 Td 56.583333 Tz (James ) Tj 1.9075 0 Td 51.041667 Tz (A. ) Tj 0.8225 0 Td 56.510417 Tz (Anderson ) Tj 2.7475 0 Td 14.583333 Tz (, ) Tj 58.857143 0 0 58.857143 0 2191.738636 Tm 10.126214 0 Td 54.510518 Tz (Woodbury ) Tj 2.565534 0 Td 28.317152 Tz (, ) Tj 0.441748 0 Td 83.535599 Tz (MN ) Tj 1.257282 0 Td 31.148867 Tz (\( ) Tj 0.152913 0 Td 69.377023 Tz (US ) Tj 0.883495 0 Td 28.317152 Tz (\) ) Tj 0.118932 0 Td 28.317152 Tz (; ) Tj 0.458738 0 Td 44.174757 Tz (Sixin ) Tj 1.580097 0 Td 50.970874 Tz (Liu ) Tj 0.968447 0 Td 14.158576 Tz (, ) Tj 56.428571 0 0 56.428571 0 2147.813559 Tm 10.579747 0 Td 41.596343 Tz (Purcellville ) Tj 3.012658 0 Td 26.582278 Tz (, ) Tj 0.407595 0 Td 72.362869 Tz (VA ) Tj 1.098734 0 Td 38.396624 Tz (\( ) Tj 0.212658 0 Td 66.455696 Tz (US ) Tj 0.832911 0 Td 29.535865 Tz (\) ) Tj 58.253968 0 0 58.253968 0 2071.705219 Tm 5.544687 0 Td 28.610354 Tz (\( ) Tj 0.205995 0 Td 47.207084 Tz (73 ) Tj 0.63515 0 Td 28.610354 Tz (\) ) Tj 0.841144 0 Td 47.683924 Tz (Assignees ) Tj 2.660763 0 Td 11.444142 Tz (: ) Tj 0.343324 0 Td 54.359673 Tz (Kansas ) Tj 2.231608 0 Td 44.632153 Tz (State ) Tj 1.596458 0 Td 47.207084 Tz (University ) Tj 3.072752 0 Td 51.856267 Tz (Research ) Tj 57.142857 0 0 57.142857 0 2027 Tm 10.4475 0 Td 53.666667 Tz (Foundation ) Tj 3.2725 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 49.907407 Tz (Manhattan ) Tj 2.7825 0 Td 26.25 Tz (, ) Tj 0.4025 0 Td 65.625 Tz (KS ) Tj 1.0675 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 67.083333 Tz (US ) Tj 0.8575 0 Td 29.166667 Tz (\) ) Tj 0.245 0 Td 14.583333 Tz (; ) Tj 57.142857 0 0 57.142857 0 1991.099291 Tm 10.43 0 Td 52.083333 Tz (Regents ) Tj 2.4675 0 Td 45.208333 Tz (of ) Tj 0.7525 0 Td 56.388889 Tz (The ) Tj 1.2775 0 Td 48.416667 Tz (University ) Tj 3.1325 0 Td 62.708333 Tz (Of ) Tj 58.571429 0 0 58.571429 0 1945.384146 Tm 10.192683 0 Td 52.800361 Tz (Minnesota ) Tj 2.902439 0 Td 14.227642 Tz (, ) Tj 0.358537 0 Td 47.856615 Tz (Minneapolis ) Tj 3.12439 0 Td 28.455285 Tz (, ) Tj 0.443902 0 Td 83.943089 Tz (MN ) Tj 1.246341 0 Td 28.455285 Tz (\( ) Tj 0.187805 0 Td 65.447154 Tz (US ) Tj 0.836585 0 Td 28.455285 Tz (\) ) Tj 55.714286 0 0 55.714286 0 2315.383085 Tm 23.279487 0 Td 46.367521 Tz (Bernardo ) Tj 2.171795 0 Td 23.931624 Tz (, ) Tj 0.305128 0 Td 64.814815 Tz (Amy ) Tj 1.310256 0 Td 44.871795 Tz (N. ) Tj 0.610256 0 Td 11.965812 Tz (, ) Tj 0.269231 0 Td 32.905983 Tz (et ) Tj 0.55641 0 Td 32.905983 Tz (al ) Tj 0.466667 0 Td 8.974359 Tz (. ) Tj 0.251282 0 Td 26.923077 Tz ( ) Tj 0.305128 0 Td 40.384615 Tz (Single ) Tj 1.597436 0 Td 41.282051 Tz (nucleotide ) Tj 2.620513 0 Td 48.361823 Tz (polymorphism ) Tj 3.625641 0 Td 37.393162 Tz (in ) Tj 0.592308 0 Td 47.264957 Tz (wheat ) Tj 54.285714 0 0 54.285714 0 2272.108144 Tm 23.892105 0 Td 52.192982 Tz (chromosome ) Tj 3.518421 0 Td 42.982456 Tz (region ) Tj 1.915789 0 Td 44.005848 Tz (harboring ) Tj 2.781579 0 Td 48.355263 Tz (Fhbl ) Tj 1.621053 0 Td 37.865497 Tz (for ) Tj 1.068421 0 Td 47.971491 Tz (Fusarium ) Tj 2.671053 0 Td 48.355263 Tz (head ) Tj 1.510526 0 Td 39.912281 Tz (blight ) Tj 57.142857 0 0 57.142857 0 2224.121771 Tm 22.7325 0 Td 37.333333 Tz (resistance ) Tj 2.1875 0 Td 35 Tz (. ) Tj 0.175 0 Td 35 Tz ( ) Tj 0.3675 0 Td 43.425926 Tz (Molecular ) Tj 2.45 0 Td 41.5625 Tz (breeding ) Tj 2.135 0 Td 40.104167 Tz (29.2 ) Tj 1.12 0 Td 26.25 Tz (\( ) Tj 0.1925 0 Td 45.9375 Tz (2012 ) Tj 1.1375 0 Td 26.25 Tz (\) ) Tj 0.2275 0 Td 8.75 Tz (: ) Tj 0.21 0 Td 45 Tz (477-488 ) Tj 1.9775 0 Td 8.75 Tz (. ) Tj 0.21 0 Td 32.083333 Tz (\( ) Tj 0.315 0 Td 40.833333 Tz (Year ) Tj 0.9275 0 Td 26.25 Tz (: ) Tj 0.28 0 Td 45.9375 Tz (2012 ) Tj 1.155 0 Td 26.25 Tz (\) ) Tj 0.21 0 Td 8.75 Tz (. ) Tj 0.14 0 Td 35 Tz (* ) Tj 54.285714 0 0 54.285714 0 2186.054759 Tm 23.892105 0 Td 39.676113 Tz (International ) Tj 3.407895 0 Td 45.02924 Tz (Search ) Tj 1.915789 0 Td 45.540936 Tz (Report ) Tj 1.915789 0 Td 49.122807 Tz (and ) Tj 1.123684 0 Td 43.859649 Tz (Written ) Tj 2.118421 0 Td 47.368421 Tz (Opinion ) Tj 2.284211 0 Td 43.596491 Tz (dated ) Tj 1.565789 0 Td 46.820175 Tz (Nov. ) Tj 1.436842 0 Td 46.052632 Tz (23 ) Tj 0.644737 0 Td 12.280702 Tz (, ) Tj 51.428571 0 0 51.428571 0 2146.839931 Tm 25.219444 0 Td 51.041667 Tz (2015 ) Tj 1.302778 0 Td 12.962963 Tz (, ) Tj 0.369444 0 Td 38.888889 Tz (in ) Tj 0.7 0 Td 43.209877 Tz (the ) Tj 1.011111 0 Td 63.734568 Tz (PCT ) Tj 1.166667 0 Td 29.166667 Tz (/ ) Tj 0.194444 0 Td 59.143519 Tz (US15 ) Tj 1.477778 0 Td 29.166667 Tz (/ ) Tj 0.194444 0 Td 51.851852 Tz (33290 ) Tj 1.827778 0 Td 37.592593 Tz (filed ) Tj 1.361111 0 Td 65.895062 Tz (May ) Tj 1.4 0 Td 50.231481 Tz (29 ) Tj 0.661111 0 Td 12.962963 Tz (, ) Tj 0.369444 0 Td 51.041667 Tz (2015 ) Tj 1.322222 0 Td 9.722222 Tz (. ) Tj 55.714286 0 0 55.714286 0 2107.136954 Tm 23.279487 0 Td 48.985043 Tz (Gunnauah ) Tj 2.387179 0 Td 23.931624 Tz (, ) Tj 0.287179 0 Td 47.047397 Tz (Raghavendra ) Tj 3.230769 0 Td 26.923077 Tz ( ) Tj 0.358974 0 Td 37.257187 Tz (Intergrated ) Tj 2.584615 0 Td 45.245726 Tz (Matabolo ) Tj 2.333333 0 Td 17.948718 Tz (- ) Tj 0.089744 0 Td 44.539411 Tz (Proteomic ) Tj 2.530769 0 Td 47.863248 Tz (Approach ) Tj 52.857143 0 0 52.857143 0 2065.620915 Tm 24.518919 0 Td 37.837838 Tz (to ) Tj 0.737838 0 Td 47.691441 Tz (Decipher ) Tj 2.535135 0 Td 42.042042 Tz (the ) Tj 1.021622 0 Td 52.342342 Tz (Mechanisms ) Tj 3.405405 0 Td 53.603604 Tz (by ) Tj 0.851351 0 Td 55.495495 Tz (Which ) Tj 1.910811 0 Td 54.234234 Tz (Wheat ) Tj 1.891892 0 Td 66.216216 Tz (QTL ) Tj 1.437838 0 Td 28.378378 Tz (\( ) Tj 0.208108 0 Td 50.45045 Tz (Fhbl ) Tj 1.305405 0 Td 28.378378 Tz (\) ) Tj 0.510811 0 Td 64.114114 Tz (Con ) Tj 55.714286 0 0 55.714286 0 2027.582598 Tm 23.261538 0 Td 37.019231 Tz (tributes ) Tj 1.974359 0 Td 35.897436 Tz (to ) Tj 0.664103 0 Td 42.179487 Tz (Resistance ) Tj 2.746154 0 Td 39.74359 Tz (against ) Tj 1.866667 0 Td 46.741453 Tz (Fusarium ) Tj 2.441026 0 Td 44.327894 Tz (graminearum ) Tj 3.230769 0 Td 26.923077 Tz (, ) Tj 0.179487 0 Td 26.923077 Tz ( ) Tj 0.376923 0 Td 53.846154 Tz (PLoS ) Tj 1.507692 0 Td 53.846154 Tz (One ) Tj 1.023077 0 Td 11.965812 Tz (, ) Tj 47.142857 0 0 47.142857 0 1990.832536 Tm 27.512121 0 Td 49.494949 Tz (Jul ) Tj 0.848485 0 Td 21.212121 Tz (. ) Tj 0.381818 0 Td 56.565657 Tz (2012 ) Tj 1.442424 0 Td 14.141414 Tz (, ) Tj 0.360606 0 Td 48.316498 Tz (vol ) Tj 0.975758 0 Td 10.606061 Tz (. ) Tj 0.360606 0 Td 49.494949 Tz (7 ) Tj 0.593939 0 Td 31.818182 Tz (\( ) Tj 0.233333 0 Td 49.494949 Tz (7 ) Tj 0.339394 0 Td 31.818182 Tz (\) ) Tj 0.275758 0 Td 10.606061 Tz (. ) Tj 53.809524 0 0 53.809524 0 1952.345411 Tm 24.10354 0 Td 64.011799 Tz (TSA ) Tj 1.207965 0 Td 9.292035 Tz (: ) Tj 0.297345 0 Td 44.524336 Tz (Triticum ) Tj 2.341593 0 Td 46.073009 Tz (aestivum ) Tj 2.415929 0 Td 38.716814 Tz (cultivar ) Tj 2.044248 0 Td 49.275945 Tz (Wangshuibai ) Tj 3.177876 0 Td 27.876106 Tz (, ) Tj 0.371681 0 Td 43.362832 Tz (transcriptome ) Tj 3.623894 0 Td 48.783186 Tz (shot ) Tj 56.428571 0 0 56.428571 0 1915.449438 Tm 22.949367 0 Td 48.241913 Tz (gun ) Tj 1.081013 0 Td 47.626582 Tz (assembly ) Tj 55.714286 0 0 55.714286 0 1872.199498 Tm 23.261538 0 Td 47.115385 Tz (Xiao ) Tj 1.202564 0 Td 11.965812 Tz (, ) Tj 0.323077 0 Td 36.894587 Tz (Jin ) Tj 0.717949 0 Td 11.965812 Tz (, ) Tj 0.323077 0 Td 26.923077 Tz ( ) Tj 0.358974 0 Td 44.18146 Tz (Transcriptome ) Tj 3.410256 0 Td 26.923077 Tz (- ) Tj 0.161538 0 Td 44.871795 Tz (based ) Tj 1.561538 0 Td 42.545109 Tz (discovery ) Tj 2.512821 0 Td 44.871795 Tz (of ) Tj 0.682051 0 Td 46.367521 Tz (pathways ) Tj 2.458974 0 Td 47.863248 Tz (and ) Tj 1.058974 0 Td 44.273504 Tz (genes ) Tj 52.857143 0 0 52.857143 0 1830.668293 Tm 24.518919 0 Td 40.990991 Tz (related ) Tj 1.854054 0 Td 39.414414 Tz (to ) Tj 0.643243 0 Td 41.306306 Tz (resistance ) Tj 2.667568 0 Td 41.891892 Tz (against ) Tj 1.92973 0 Td 49.268018 Tz (Fusarium ) Tj 2.516216 0 Td 49.662162 Tz (head ) Tj 1.324324 0 Td 40.990991 Tz (blight ) Tj 1.645946 0 Td 37.837838 Tz (in ) Tj 0.624324 0 Td 49.81982 Tz (wheat ) Tj 1.664865 0 Td 43.75 Tz (landrace ) Tj 55.714286 0 0 55.714286 0 1791.323432 Tm 23.261538 0 Td 47.863248 Tz (Wangshuibai ) Tj 3.105128 0 Td 32.905983 Tz (, ) Tj 0.14359 0 Td 32.905983 Tz ( ) Tj 0.484615 0 Td 71.794872 Tz (BMC ) Tj 1.525641 0 Td 49.732906 Tz (Genomics ) Tj 2.620513 0 Td 47.115385 Tz (2013 ) Tj 1.202564 0 Td 11.965812 Tz (, ) Tj 0.323077 0 Td 40.883191 Tz (vol ) Tj 0.807692 0 Td 8.974359 Tz (. ) Tj 0.376923 0 Td 40.384615 Tz (14 ) Tj 0.735897 0 Td 26.923077 Tz (\( ) Tj 0.251282 0 Td 43.874644 Tz (197 ) Tj 0.84359 0 Td 26.923077 Tz (\) ) Tj 0.233333 0 Td 8.974359 Tz (. ) Tj 57.142857 0 0 57.142857 0 1751.65982 Tm 22.6975 0 Td 38.402778 Tz (Office ) Tj 1.5925 0 Td 43.263889 Tz (Action ) Tj 1.82 0 Td 35 Tz (in ) Tj 0.665 0 Td 42.403846 Tz (corresponding ) Tj 3.535 0 Td 41.5625 Tz (U.S. ) Tj 1.2425 0 Td 51.041667 Tz (Appl ) Tj 1.1025 0 Td 26.25 Tz (. ) Tj 0.4025 0 Td 45.694444 Tz (No. ) Tj 1.155 0 Td 37.916667 Tz (15 ) Tj 0.5075 0 Td 26.25 Tz (/ ) Tj 0.175 0 Td 43.75 Tz (315,139 ) Tj 1.9075 0 Td 11.666667 Tz (, ) Tj 0.35 0 Td 41.416667 Tz (dated ) Tj 45.714286 0 0 45.714286 0 1716 Tm 28.35 0 Td 50.130208 Tz (Feb. ) Tj 1.509375 0 Td 56.510417 Tz (22 ) Tj 0.74375 0 Td 14.583333 Tz (, ) Tj 0.415625 0 Td 58.333333 Tz (2018 ) Tj 1.4875 0 Td 10.9375 Tz (. ) Tj 54.285714 0 0 54.285714 0 1672.666667 Tm 23.892105 0 Td 40.423977 Tz (Office ) Tj 1.676316 0 Td 45.540936 Tz (Action ) Tj 1.915789 0 Td 36.842105 Tz (in ) Tj 0.7 0 Td 44.635628 Tz (corresponding ) Tj 3.721053 0 Td 43.75 Tz (U.S. ) Tj 1.307895 0 Td 54.495614 Tz (Appl ) Tj 1.160526 0 Td 27.631579 Tz (. ) Tj 0.423684 0 Td 48.099415 Tz (No. ) Tj 1.215789 0 Td 39.912281 Tz (15 ) Tj 0.534211 0 Td 27.631579 Tz (/ ) Tj 0.184211 0 Td 46.052632 Tz (315,139 ) Tj 2.007895 0 Td 12.280702 Tz (, ) Tj 0.368421 0 Td 43.596491 Tz (dated ) Tj 44.52381 0 0 44.52381 0 1635.550336 Tm 29.130481 0 Td 49.910873 Tz (Jul ) Tj 0.853476 0 Td 26.203209 Tz (. ) Tj 0.449198 0 Td 58.02139 Tz (26 ) Tj 0.763636 0 Td 14.973262 Tz (, ) Tj 0.426738 0 Td 59.893048 Tz (2018 ) Tj 1.527273 0 Td 11.229947 Tz (. ) Tj 56.571429 0 0 56.571429 0 1866.946309 Tm 5.691919 0 Td 35.353535 Tz (\( ) Tj 0.424242 0 Td 41.245791 Tz (* ) Tj 0.441919 0 Td 35.353535 Tz (\) ) Tj 0.883838 0 Td 50.084175 Tz (Notice ) Tj 1.767677 0 Td 26.515152 Tz (: ) Tj 56.825397 0 0 56.825397 0 1869.277174 Tm 10.505866 0 Td 46.089385 Tz (Subject ) Tj 2.111732 0 Td 39.594972 Tz (to ) Tj 0.686313 0 Td 50.837989 Tz (any ) Tj 1.108659 0 Td 45.75419 Tz (disclaimer ) Tj 2.762849 0 Td 14.664804 Tz (, ) Tj 0.281564 0 Td 44.972067 Tz (the ) Tj 0.967877 0 Td 50.593575 Tz (term ) Tj 1.390223 0 Td 49.860335 Tz (of ) Tj 0.686313 0 Td 38.861732 Tz (this ) Tj 60.204082 0 0 60.204082 0 1826.003831 Tm 9.883051 0 Td 42.448211 Tz (patent ) Tj 1.810508 0 Td 30.451977 Tz (is ) Tj 0.664407 0 Td 46.024011 Tz (extended ) Tj 2.508136 0 Td 42.909605 Tz (or ) Tj 0.780678 0 Td 42.909605 Tz (adjusted ) Tj 2.308814 0 Td 47.615819 Tz (under ) Tj 1.694237 0 Td 47.062147 Tz (35 ) Tj 60.47619 0 0 60.47619 0 1781.408955 Tm 9.855118 0 Td 45.472441 Tz (U.S.C. ) Tj 1.951181 0 Td 45.013123 Tz (154 ) Tj 0.925984 0 Td 27.559055 Tz (\( ) Tj 0.198425 0 Td 27.559055 Tz (b ) Tj 0.264567 0 Td 27.559055 Tz (\) ) Tj 0.39685 0 Td 50.984252 Tz (by ) Tj 0.892913 0 Td 45.931759 Tz (142 ) Tj 1.074803 0 Td 45.472441 Tz (days ) Tj 1.174016 0 Td 11.023622 Tz (. ) Tj 57.142857 0 0 57.142857 0 1704.146974 Tm 5.6525 0 Td 29.166667 Tz (\( ) Tj 0.21 0 Td 45.208333 Tz (21 ) Tj 0.6475 0 Td 29.166667 Tz (\) ) Tj 0.8575 0 Td 53.229167 Tz (Appl ) Tj 1.365 0 Td 11.666667 Tz (. ) Tj 0.3325 0 Td 64.166667 Tz (No ) Tj 0.84 0 Td 20.416667 Tz (.: ) Tj 0.5425 0 Td 45.208333 Tz (16 ) Tj 0.6475 0 Td 26.25 Tz (/ ) Tj 0.14 0 Td 50.416667 Tz (504,535 ) Tj 57.142857 0 0 57.142857 0 1623 Tm 5.67 0 Td 29.166667 Tz (\( ) Tj 0.21 0 Td 49.583333 Tz (22 ) Tj 0.6475 0 Td 29.166667 Tz (\) ) Tj 44.285714 0 0 44.285714 0 1630 Tm 9.529032 0 Td 57.204301 Tz (Filed ) Tj 1.783871 0 Td 15.053763 Tz (: ) Tj 52.857143 0 0 52.857143 0 1624 Tm 11.294595 0 Td 51.501502 Tz (Jul ) Tj 0.964865 0 Td 18.918919 Tz (. ) Tj 0.397297 0 Td 50.45045 Tz (8 ) Tj 0.359459 0 Td 22.072072 Tz (, ) Tj 0.416216 0 Td 56.756757 Tz (2019 ) Tj 55.714286 0 0 55.714286 0 1544 Tm 5.797436 0 Td 29.91453 Tz (\( ) Tj 0.233333 0 Td 47.863248 Tz (65 ) Tj 0.646154 0 Td 29.91453 Tz (\) ) Tj 51.428571 0 0 51.428571 0 1545 Tm 12.386111 0 Td 54.444444 Tz (Prior ) Tj 1.886111 0 Td 53.619529 Tz (Publication ) Tj 3.811111 0 Td 60.763889 Tz (Data ) Tj 55 0 0 55 0 1552.651341 Tm 23.618182 0 Td 39.393939 Tz (* ) Tj 0.527273 0 Td 43.636364 Tz (cited ) Tj 1.527273 0 Td 56.060606 Tz (by ) Tj 0.927273 0 Td 52.651515 Tz (examiner ) Tj 47.142857 0 0 47.142857 0 1487 Tm 8.951515 0 Td 81.313131 Tz (US ) Tj 1.293939 0 Td 63.047138 Tz (2019/0323026 ) Tj 4.793939 0 Td 72.474747 Tz (A1 ) Tj 48.571429 0 0 48.571429 0 1485 Tm 16.902941 0 Td 51.470588 Tz (Oct. ) Tj 1.564706 0 Td 60.04902 Tz (24 ) Tj 0.782353 0 Td 17.156863 Tz (, ) Tj 0.432353 0 Td 61.764706 Tz (2019 ) Tj 52.857143 0 0 52.857143 0 1475.399093 Tm 24.481081 0 Td 56.756757 Tz (Primary ) Tj 2.591892 0 Td 58.333333 Tz (Examiner ) Tj 3.802703 0 Td 58.333333 Tz (Weihua ) Tj 2.364865 0 Td 58.858859 Tz (Fan ) Tj 56.904762 0 0 56.904762 0 1426.695279 Tm 22.792469 0 Td 29.288703 Tz (\( ) Tj 0.193305 0 Td 51.25523 Tz (74 ) Tj 0.667782 0 Td 29.288703 Tz (\) ) Tj 0.509623 0 Td 47.228033 Tz (Attorney ) Tj 2.196653 0 Td 26.359833 Tz (, ) Tj 0.386611 0 Td 53.305439 Tz (Agent ) Tj 1.546444 0 Td 26.359833 Tz (, ) Tj 0.421757 0 Td 48.32636 Tz (or ) Tj 0.773222 0 Td 54.1841 Tz (Firm ) Tj 2.266946 0 Td 57.991632 Tz (Hovey ) Tj 1.950628 0 Td 49.058577 Tz (Williams ) Tj 2.600837 0 Td 64.435146 Tz (LLP ) Tj 56.785714 0 0 56.785714 0 1419.302013 Tm 9.298113 0 Td 50.733753 Tz (Related ) Tj 2.377358 0 Td 46.960168 Tz (U.S. ) Tj 1.338365 0 Td 49.628359 Tz (Application ) Tj 3.522013 0 Td 55.765199 Tz (Data ) Tj 57.362637 0 0 57.362637 0 1355.123037 Tm 5.630843 0 Td 34.8659 Tz (\( ) Tj 0.226628 0 Td 49.393359 Tz (63 ) Tj 0.627586 0 Td 34.8659 Tz (\) ) Tj 0.88908 0 Td 47.21424 Tz (Continuation ) Tj 3.626054 0 Td 47.940613 Tz (of ) Tj 0.749617 0 Td 43.846511 Tz (application ) Tj 3.103065 0 Td 50.361856 Tz (No. ) Tj 1.237739 0 Td 45.035121 Tz (15 ) Tj 0.59272 0 Td 29.054917 Tz (/ ) Tj 0.191762 0 Td 49.393359 Tz (315,139 ) Tj 2.144253 0 Td 14.527458 Tz (, ) Tj 0.348659 0 Td 38.35249 Tz (filed ) Tj 1.377203 0 Td 42.12963 Tz (as ) Tj 64.285714 0 0 64.285714 0 1313.093333 Tm 6.58 0 Td 38.888889 Tz (application ) Tj 2.877778 0 Td 45.802469 Tz (No. ) Tj 1.182222 0 Td 63.08642 Tz (PCT ) Tj 1.12 0 Td 18.148148 Tz (/ ) Tj 0.093333 0 Td 51.851852 Tz (US2015 ) Tj 2.006667 0 Td 18.148148 Tz (/ ) Tj 0.155556 0 Td 45.802469 Tz (033290 ) Tj 1.975556 0 Td 47.962963 Tz (on ) Tj 0.902222 0 Td 57.901235 Tz (May ) Tj 1.368889 0 Td 45.37037 Tz (29 ) Tj 0.606667 0 Td 12.962963 Tz (, ) Tj 57.142857 0 0 57.142857 0 1272 Tm 7.4025 0 Td 51.770833 Tz (2015 ) Tj 1.33 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 61.25 Tz (now ) Tj 1.3475 0 Td 45.694444 Tz (Pat ) Tj 0.875 0 Td 11.666667 Tz (. ) Tj 0.3325 0 Td 51.527778 Tz (No. ) Tj 1.26 0 Td 47.25 Tz (10,344,297 ) Tj 2.9225 0 Td 11.666667 Tz (. ) Tj 65.714286 0 0 65.714286 0 1214.982005 Tm 4.930435 0 Td 20.289855 Tz (\( ) Tj 0.182609 0 Td 45.652174 Tz (60 ) Tj 0.578261 0 Td 25.362319 Tz (\) ) Tj 0.76087 0 Td 38.504611 Tz (Provisional ) Tj 2.708696 0 Td 38.274045 Tz (application ) Tj 2.678261 0 Td 44.806763 Tz (No. ) Tj 0.973913 0 Td 49.456522 Tz (62 ) Tj 0.623913 0 Td 20.289855 Tz (/ ) Tj 0.136957 0 Td 41.666667 Tz (005,079 ) Tj 1.81087 0 Td 20.289855 Tz (, ) Tj 0.28913 0 Td 33.478261 Tz (filed ) Tj 1.156522 0 Td 45.652174 Tz (on ) Tj 0.730435 0 Td 55.797101 Tz (May ) Tj 54.285714 0 0 54.285714 0 1177 Tm 7.773684 0 Td 56.798246 Tz (30 ) Tj 0.7 0 Td 18.421053 Tz (, ) Tj 0.478947 0 Td 52.960526 Tz (2014 ) Tj 55.714286 0 0 55.714286 0 1342 Tm 23.279487 0 Td 29.91453 Tz (\( ) Tj 0.215385 0 Td 50.854701 Tz (57 ) Tj 0.664103 0 Td 29.91453 Tz (\) ) Tj 47.142857 0 0 47.142857 0 1347 Tm 34.851515 0 Td 89.709596 Tz (ABSTRACT ) Tj 61.428571 0 0 61.428571 0 1279.676471 Tm 21.113953 0 Td 49.612403 Tz (Methods ) Tj 2.327907 0 Td 47.932817 Tz (and ) Tj 1.05814 0 Td 46.124031 Tz (recombinant ) Tj 3.255814 0 Td 41.085271 Tz (vectors ) Tj 1.969767 0 Td 38.888889 Tz (for ) Tj 0.911628 0 Td 41.24031 Tz (increasing ) Tj 2.686047 0 Td 39.883721 Tz (resistance ) Tj 56.071429 0 0 56.071429 0 1240.279895 Tm 23.113376 0 Td 40.127389 Tz (to ) Tj 0.766879 0 Td 53.503185 Tz (Fusarium ) Tj 2.853503 0 Td 52.760085 Tz (head ) Tj 1.533758 0 Td 42.604388 Tz (blight ) Tj 1.836943 0 Td 29.723992 Tz (\( ) Tj 0.214013 0 Td 69.35598 Tz (FHB ) Tj 1.301911 0 Td 29.723992 Tz (\) ) Tj 0.463694 0 Td 43.925454 Tz (infection ) Tj 2.63949 0 Td 41.613588 Tz (in ) Tj 0.749045 0 Td 43.595188 Tz (plants ) Tj 1.587261 0 Td 29.723992 Tz (. ) Tj 0.535032 0 Td 62.420382 Tz (Exog ) Tj 55.714286 0 0 55.714286 0 1194.322835 Tm 23.279487 0 Td 50.854701 Tz (enous ) Tj 1.830769 0 Td 53.098291 Tz (Fhbl ) Tj 1.633333 0 Td 45.299145 Tz (nucleic ) Tj 2.225641 0 Td 44.273504 Tz (acids ) Tj 1.651282 0 Td 43.874644 Tz (are ) Tj 1.076923 0 Td 47.530864 Tz (described ) Tj 2.817949 0 Td 41.880342 Tz (to ) Tj 0.807692 0 Td 47.115385 Tz (generate ) Tj 2.566667 0 Td 50.854701 Tz (trans ) Tj 60.31746 0 0 60.31746 0 1151.553165 Tm 21.486316 0 Td 43.105263 Tz (genic ) Tj 1.525263 0 Td 40.526316 Tz (plants ) Tj 1.674474 0 Td 46.513158 Tz (having ) Tj 1.89 0 Td 43.289474 Tz (increased ) Tj 2.52 0 Td 40.618421 Tz (resistance ) Tj 2.652632 0 Td 37.302632 Tz (to ) Tj 0.696316 0 Td 63.552632 Tz (FHB ) Tj 1.376053 0 Td 38.684211 Tz (relative ) Tj 2.055789 0 Td 37.302632 Tz (to ) Tj 59.857143 0 0 59.857143 0 1108.670455 Tm 21.668258 0 Td 41.76611 Tz (a ) Tj 0.501193 0 Td 40.970565 Tz (control ) Tj 1.97136 0 Td 45.107399 Tz (plant ) Tj 1.186158 0 Td 27.844073 Tz (. ) Tj 0.434368 0 Td 52.903739 Tz (The ) Tj 1.186158 0 Td 42.879873 Tz (nucleotide ) Tj 2.840095 0 Td 46.986874 Tz (sequence ) Tj 2.48926 0 Td 47.334924 Tz (of ) Tj 0.718377 0 Td 41.76611 Tz (the ) Tj 1.002387 0 Td 48.881817 Tz (exogenous ) Tj 58.571429 0 0 58.571429 0 1062.972059 Tm 22.126829 0 Td 43.089431 Tz (nucleic ) Tj 2.082927 0 Td 43.394309 Tz (acid ) Tj 1.280488 0 Td 47.109304 Tz (comprises ) Tj 2.817073 0 Td 64.498645 Tz (SEQ ) Tj 1.4 0 Td 54.065041 Tz (ID ) Tj 0.887805 0 Td 75.406504 Tz (NO ) Tj 0.973171 0 Td 11.382114 Tz (: ) Tj 0.187805 0 Td 28.455285 Tz (1 ) Tj 0.290244 0 Td 14.227642 Tz (, ) Tj 0.358537 0 Td 45.528455 Tz (2 ) Tj 0.32439 0 Td 14.227642 Tz (, ) Tj 0.358537 0 Td 45.528455 Tz (4 ) Tj 0.341463 0 Td 14.227642 Tz (, ) Tj 0.37561 0 Td 39.837398 Tz (5 ) Tj 0.32439 0 Td 14.227642 Tz (, ) Tj 0.358537 0 Td 44.105691 Tz (or ) Tj 0.768293 0 Td 42.682927 Tz (6 ) Tj 0.341463 0 Td 14.227642 Tz (; ) Tj 0.341463 0 Td 45.528455 Tz (has ) Tj 1.07561 0 Td 36.99187 Tz (at ) Tj 60 0 0 60 0 1022.221739 Tm 21.616667 0 Td 37.222222 Tz (least ) Tj 1.35 0 Td 44.444444 Tz (95 ) Tj 0.6 0 Td 80.555556 Tz (% ) Tj 0.716667 0 Td 46.875 Tz (sequence ) Tj 2.466667 0 Td 38.888889 Tz (identity ) Tj 2.066667 0 Td 37.5 Tz (to ) Tj 0.7 0 Td 62.962963 Tz (SEQ ) Tj 1.35 0 Td 51.388889 Tz (ID ) Tj 0.833333 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.183333 0 Td 27.777778 Tz (1 ) Tj 0.283333 0 Td 13.888889 Tz (, ) Tj 0.316667 0 Td 44.444444 Tz (2 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 0.316667 0 Td 44.444444 Tz (4 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 0.35 0 Td 38.888889 Tz (5 ) Tj 0.3 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 41.666667 Tz (or ) Tj 0.716667 0 Td 41.666667 Tz (6 ) Tj 0.333333 0 Td 13.888889 Tz (; ) Tj 67.142857 0 0 67.142857 0 979.284238 Tm 19.317021 0 Td 41.843972 Tz (encodes ) Tj 2.010638 0 Td 37.234043 Tz (a ) Tj 0.446809 0 Td 37.943262 Tz (protein ) Tj 1.817021 0 Td 41.453901 Tz (comprising ) Tj 2.710638 0 Td 37.234043 Tz (the ) Tj 0.908511 0 Td 45.177305 Tz (amino ) Tj 1.608511 0 Td 38.475177 Tz (acid ) Tj 1.161702 0 Td 41.888298 Tz (sequence ) Tj 2.248936 0 Td 42.198582 Tz (of ) Tj 57.142857 0 0 57.142857 0 938.138201 Tm 22.715 0 Td 66.111111 Tz (SEQ ) Tj 1.3475 0 Td 55.416667 Tz (ID ) Tj 0.805 0 Td 77.291667 Tz (NO ) Tj 0.9975 0 Td 11.666667 Tz (: ) Tj 0.2975 0 Td 50.75 Tz (3,7,8 ) Tj 1.5925 0 Td 14.583333 Tz (, ) Tj 0.28 0 Td 43.75 Tz (or ) Tj 0.7 0 Td 43.75 Tz (9 ) Tj 0.3325 0 Td 14.583333 Tz (; ) Tj 0.28 0 Td 45.208333 Tz (or ) Tj 0.6825 0 Td 49.166667 Tz (encodes ) Tj 2.24 0 Td 43.75 Tz (a ) Tj 0.4025 0 Td 41.666667 Tz (protein ) Tj 1.96 0 Td 51.041667 Tz (having ) Tj 1.9775 0 Td 36.458333 Tz (at ) Tj 0.595 0 Td 39.666667 Tz (least ) Tj 61.428571 0 0 61.428571 0 896.605096 Tm 21.130233 0 Td 44.767442 Tz (95 ) Tj 0.586047 0 Td 78.682171 Tz (% ) Tj 0.716279 0 Td 49.379845 Tz (amino ) Tj 1.725581 0 Td 42.054264 Tz (acid ) Tj 1.22093 0 Td 37.984496 Tz (identity ) Tj 2.051163 0 Td 36.627907 Tz (to ) Tj 0.7 0 Td 61.498708 Tz (SEQ ) Tj 1.334884 0 Td 51.550388 Tz (ID ) Tj 0.830233 0 Td 71.899225 Tz (NO ) Tj 0.927907 0 Td 10.852713 Tz (: ) Tj 0.34186 0 Td 40.697674 Tz (3 ) Tj 0.325581 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 43.410853 Tz (7 ) Tj 0.309302 0 Td 13.565891 Tz (, ) Tj 0.35814 0 Td 40.697674 Tz (8 ) Tj 0.309302 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 40.697674 Tz (or ) Tj 0.813953 0 Td 32.55814 Tz (9 ) Tj 0.260465 0 Td 21.705426 Tz (. ) Tj 52.857143 0 0 52.857143 0 1098 Tm 6.12973 0 Td 31.531532 Tz (\( ) Tj 0.245946 0 Td 47.297297 Tz (51 ) Tj 0.681081 0 Td 31.531532 Tz (\) ) Tj 54.761905 0 0 54.761905 0 970.189655 Tm 5.898261 0 Td 33.478261 Tz (\( ) Tj 0.237391 0 Td 53.26087 Tz (52 ) Tj 0.657391 0 Td 36.521739 Tz (\) ) Tj 45 0 0 45 0 1104.063158 Tm 9.377778 0 Td 56.790123 Tz (Int ) Tj 1.088889 0 Td 22.222222 Tz (. ) Tj 0.444444 0 Td 68.518519 Tz (Cl ) Tj 0.866667 0 Td 22.222222 Tz (. ) Tj 45.714286 0 0 45.714286 0 1062 Tm 9.275 0 Td 82.942708 Tz (C12N ) Tj 2.209375 0 Td 60.520833 Tz (15/82 ) Tj 56.666667 0 0 56.666667 0 1054.222222 Tm 13.623529 0 Td 29.411765 Tz (\( ) Tj 0.211765 0 Td 48.319328 Tz (2006.01 ) Tj 2.135294 0 Td 29.411765 Tz (\) ) Tj 47.142857 0 0 47.142857 0 1019 Tm 8.993939 0 Td 77.777778 Tz (COZK ) Tj 2.1 0 Td 60.690236 Tz (14/415 ) Tj 52.380952 0 0 52.380952 0 1015.160584 Tm 14.738182 0 Td 38.181818 Tz (\( ) Tj 0.324545 0 Td 52.272727 Tz (2006.01 ) Tj 2.233636 0 Td 31.818182 Tz (\) ) Tj 48.571429 0 0 48.571429 0 975 Tm 8.708824 0 Td 54.901961 Tz (U.S. ) Tj 1.626471 0 Td 61.764706 Tz (CI ) Tj 0.782353 0 Td 20.588235 Tz (. ) Tj 54.761905 0 0 54.761905 0 926.675367 Tm 7.706087 0 Td 70 Tz (CPC ) Tj 3.469565 0 Td 69.23913 Tz (C12N ) Tj 1.844348 0 Td 52.608696 Tz (15/8282 ) Tj 2.483478 0 Td 30.434783 Tz (\( ) Tj 0.21913 0 Td 50 Tz (2013.01 ) Tj 2.209565 0 Td 30.434783 Tz (\) ) Tj 0.273913 0 Td 15.217391 Tz (; ) Tj 0.383478 0 Td 67.717391 Tz (CO7K ) Tj 1.807826 0 Td 52.246377 Tz (14/415 ) Tj 52.380952 0 0 52.380952 0 887.075758 Tm 20.541818 0 Td 31.818182 Tz (\( ) Tj 0.229091 0 Td 51.818182 Tz (2013.01 ) Tj 2.367273 0 Td 25.454545 Tz (\) ) Tj 45.714286 0 0 45.714286 0 846 Tm 9.253125 0 Td 57.604167 Tz (Field ) Tj 2.05625 0 Td 58.333333 Tz (of ) Tj 0.940625 0 Td 55.208333 Tz (Classification ) Tj 4.9875 0 Td 64.409722 Tz (Search ) Tj 42.857143 0 0 42.857143 0 805 Tm 9.87 0 Td 89.444444 Tz (CPC ) Tj 50 0 0 50 0 801 Tm 15.36 0 Td 73.333333 Tz (C12N ) Tj 2.1 0 Td 55.714286 Tz (15/8282 ) Tj 2.44 0 Td 16.666667 Tz (; ) Tj 0.4 0 Td 74.166667 Tz (CO7K ) Tj 2.1 0 Td 53.888889 Tz (14/415 ) Tj 57.142857 0 0 57.142857 0 760.979969 Tm 7.42 0 Td 49.583333 Tz (See ) Tj 1.1375 0 Td 44.015152 Tz (application ) Tj 3.1325 0 Td 33.541667 Tz (file ) Tj 1.05 0 Td 42.777778 Tz (for ) Tj 0.98 0 Td 49.583333 Tz (complete ) Tj 2.6425 0 Td 45.694444 Tz (search ) Tj 1.855 0 Td 42.5 Tz (history ) Tj 1.785 0 Td 29.166667 Tz (. ) Tj 52.857143 0 0 52.857143 0 841 Tm 6.12973 0 Td 31.531532 Tz (\( ) Tj 0.245946 0 Td 52.027027 Tz (58 ) Tj 0.681081 0 Td 31.531532 Tz (\) ) Tj 58.571429 0 0 58.571429 0 819.074813 Tm 25.831707 0 Td 46.95122 Tz (19 ) Tj 0.836585 0 Td 51.693767 Tz (Claims ) Tj 1.912195 0 Td 19.918699 Tz (, ) Tj 0.37561 0 Td 45.528455 Tz (4 ) Tj 0.529268 0 Td 55.691057 Tz (Drawing ) Tj 2.595122 0 Td 46.95122 Tz (Sheets ) Tj 57.142857 0 0 57.142857 0 762.023064 Tm 24.465 0 Td 45.096154 Tz (Specification ) Tj 3.7625 0 Td 46.666667 Tz (includes ) Tj 2.52 0 Td 46.666667 Tz (a ) Tj 0.56 0 Td 53.229167 Tz (Sequence ) Tj 2.8175 0 Td 45.833333 Tz 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60.714286 0 1507.39 Tm 14.955294 0 Td 107.058824 Tz (Nu ) Tj 1.416471 0 Td 111.633987 Tz (478 ) Tj 57.142857 0 0 57.142857 0 1404 Tm 27.405 0 Td 88.472222 Tz (Net ) Tj 198.571429 0 0 198.571429 0 1085 Tm 7.468345 0 Td 88.129496 Tz (5 ) Tj ET Q endstream endobj 163 0 obj << /Length 1 >> stream q endstream endobj 164 0 obj << /Length 7620 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 90 0 0 90 0 3026.771084 Tm 3.6 0 Td 59.259259 Tz (U.S. ) Tj 1.777778 0 Td 62.962963 Tz (Patent ) Tj 62.857143 0 0 62.857143 0 3026 Tm 13.427273 0 Td 56.565657 Tz (Jul ) Tj 1.081818 0 Td 21.212121 Tz (. ) Tj 0.381818 0 Td 63.636364 Tz (27 ) Tj 0.795455 0 Td 26.515152 Tz (, ) Tj 0.413636 0 Td 60.984848 Tz (2021 ) Tj 57.142857 0 0 57.142857 0 3030 Tm 21.84 0 Td 66.5 Tz (Sheet ) Tj 2.31 0 Td 64.166667 Tz (2 ) Tj 0.735 0 Td 64.166667 Tz (of ) Tj 1.015 0 Td 64.166667 Tz (4 ) Tj 77.619048 0 0 77.619048 0 3023.163265 Tm 22.558896 0 Td 77.300613 Tz (US ) Tj 1.262577 0 Td 54.969325 Tz (11,072,799 ) Tj 3.581595 0 Td 68.711656 Tz (B2 ) Tj 54.285714 0 0 54.285714 0 2748 Tm 6.3 0 Td 75.219298 Tz (-NIL ) Tj 61.904762 0 0 61.904762 0 2687.125926 Tm 5.476154 0 Td 52.948718 Tz (MUT ) Tj 1.066154 0 Td 32.307692 Tz (- ) Tj 0.436154 0 Td 43.076923 Tz (1958 ) Tj 65.714286 0 0 65.714286 0 2744 Tm 9.373913 0 Td 49.456522 Tz (ITICACCAATAAAGANGGAGTIGICCGTATAAAATCCAACTATTICGACATGTTTIGGAG ) Tj 18.078261 0 Td 48.188406 Tz (2520 ) Tj 68.571429 0 0 68.571429 0 2684 Tm 8.983333 0 Td 47.395833 Tz (ITICACCAATAAAGATGGAGTTGTCCGTATAAAATCCAACTATTTCGACATGTTTTGGAG ) Tj 17.325 0 Td 46.180556 Tz (2520 ) Tj 68.571429 0 0 68.571429 0 2620 Tm 8.983333 0 Td 47.436343 Tz (117CACCAATAAAGATGGAGIIGICCGTATAARATCCAACIAITICGACAIGITTIGAAG ) Tj 17.339583 0 Td 44.965278 Tz (2520 ) Tj 62.857143 0 0 62.857143 0 2442 Tm 9.8 0 Td 51.704545 Tz (GCGAAGCCCAAATTGGATCIGGGCTGATTCANCTGACACCACCCACAACAACCGIGATAC ) Tj 18.9 0 Td 50.378788 Tz (2580 ) Tj 68.571429 0 0 68.571429 0 2380 Tm 8.983333 0 Td 47.395833 Tz (GCGAAGCCCAAATTGGATCIGGGCIGATICAACIGACACCACCCACAACAACCGIGATAC ) Tj 17.325 0 Td 46.180556 Tz (2580 ) Tj 62.857143 0 0 62.857143 0 2385.647887 Tm 5.393182 0 Td 56.565657 Tz (MUT ) Tj 1.05 0 Td 31.818182 Tz (- ) Tj 0.397727 0 Td 43.75 Tz (1958 ) Tj 44.285714 0 0 44.285714 0 2276 Tm 38.658065 0 Td 70.250896 Tz (*** ) Tj 51.904762 0 0 51.904762 0 2147 Tm 6.569725 0 Td 64.220183 Tz (R ) Tj 0.423853 0 Td 51.376147 Tz (- ) Tj 0.346789 0 Td 62.079511 Tz (NIL ) Tj 58.571429 0 0 58.571429 0 2085.151079 Tm 5.787805 0 Td 55.96206 Tz (MUT ) Tj 1.126829 0 Td 34.146341 Tz (- ) Tj 0.392683 0 Td 48.373984 Tz (1958 ) Tj 64.285714 0 0 64.285714 0 2023.144828 Tm 5.273333 0 Td 53.580247 Tz (MUT ) Tj 1.026667 0 Td 33.703704 Tz (- ) Tj 0.326667 0 Td 45.37037 Tz (1284 ) Tj 62.857143 0 0 62.857143 0 2144 Tm 9.736364 0 Td 51.969697 Tz (ATTATTCAAGGIGACCACTGGGCCCGACTICATTGCICTGCGAAACTTGGGCAACAACAA ) Tj 18.963636 0 Td 50.378788 Tz (2640 ) Tj 65.714286 0 0 65.714286 0 2082 Tm 9.343478 0 Td 49.541063 Tz (ATTATTCAAGGTGACCACIGGGCCCGACTTCATTGCICIGCGALACTTGGGCAACAACAA ) Tj 18.108696 0 Td 48.188406 Tz (2640 ) Tj 65.238095 0 0 65.238095 0 2020.20339 Tm 9.381022 0 Td 49.580968 Tz (ATTATTCAAGGIGACCACTGGGCCCGA ) Tj 10.024818 0 Td 51.19315 Tz (GCICTGCGAAACTTGGGCAACAACAA ) Tj 8.231387 0 Td 48.540146 Tz (2640 ) Tj 57.142857 0 0 57.142857 0 1842 Tm 6.02 0 Td 32.083333 Tz (R ) Tj 0.42 0 Td 32.083333 Tz (- ) Tj 0.21 0 Td 58.333333 Tz (NIL ) Tj 62.857143 0 0 62.857143 0 1842 Tm 9.8 0 Td 52.580894 Tz (117CIGCAAAAGGITAACCACAGAAGGGAAGIATGATTGCCICAAIGCTGCTGMGGTIC ) Tj 18.9 0 Td 50.378788 Tz (2700 ) Tj 65.714286 0 0 65.714286 0 1782 Tm 9.373913 0 Td 49.456522 Tz (TTICTGCALAAGGITAACCACAGLAGGGAAGIATGATIGCCICAATGCIGCIGTIGGIIC ) Tj 18.078261 0 Td 48.188406 Tz (2700 ) Tj 65.714286 0 0 65.714286 0 1722 Tm 9.373913 0 Td 49.456522 Tz (ITICIGCAAAAGGITAACCACAGAAGGGAAGIATGATIGCCICAAIGCTGCIGTIGGTIC ) Tj 18.078261 0 Td 48.188406 Tz (2700 ) Tj 62.857143 0 0 62.857143 0 1722 Tm 5.409091 0 Td 86.174242 Tz (MT ) Tj 1.05 0 Td 31.818182 Tz (- ) Tj 0.334091 0 Td 45.738636 Tz (1234 ) Tj 60 0 0 60 0 1545 Tm 5.716667 0 Td 50 Tz (R ) Tj 0.333333 0 Td 44.444444 Tz (- ) Tj 0.3 0 Td 53.703704 Tz (NIL ) Tj 68.571429 0 0 68.571429 0 1540 Tm 8.983333 0 Td 47.395833 Tz (CATCACAGCIGAAGTAAAAATGCGGIGCATIGAACCAATTGTTICTCGAGACATCIATGA ) Tj 17.325 0 Td 46.180556 Tz (2760 ) Tj 65.714286 0 0 65.714286 0 1484 Tm 9.373913 0 Td 49.541063 Tz (CAICACAGCIGAAGTAAAAAIGCGGIGCATIGAACCAATTGITTCICGAGACATCIATGA ) Tj 18.078261 0 Td 48.188406 Tz (2760 ) Tj 65.714286 0 0 65.714286 0 1424 Tm 9.373913 0 Td 49.541063 Tz (CAICACAGCIGAAGIAAAAATGCGGIGCATIGAACCAAITGTTICICGAGACATCIATGA ) Tj 18.078261 0 Td 48.188406 Tz (2760 ) Tj 61.428571 0 0 61.428571 0 1425 Tm 5.551163 0 Td 52.45478 Tz (MUT ) Tj 1.009302 0 Td 32.55814 Tz (- ) Tj 0.374419 0 Td 46.802326 Tz (1284 ) Tj 55.238095 0 0 55.238095 0 1244.791667 Tm 6.173276 0 Td 63.362069 Tz (R ) Tj 0.398276 0 Td 51.293103 Tz (- ) Tj 0.325862 0 Td 58.333333 Tz (NIL ) Tj 61.428571 0 0 61.428571 0 1185.577778 Tm 5.518605 0 Td 51.550388 Tz (MUT ) Tj 1.074419 0 Td 32.55814 Tz (- ) Tj 0.406977 0 Td 44.767442 Tz (1958 ) Tj 60 0 0 60 0 1124 Tm 5.7 0 Td 57.407407 Tz (MUT ) Tj 1.066667 0 Td 30.555556 Tz (- ) Tj 0.316667 0 Td 49.305556 Tz (1284 ) Tj 65.714286 0 0 65.714286 0 1244 Tm 9.373913 0 Td 49.456522 Tz (IGITGATIITCGCCTAGGTGAAGCTAAGANCIACACCAATGGIATTGAGGGCCTIGATAG ) Tj 18.078261 0 Td 48.188406 Tz (2820 ) Tj 88.571429 0 0 88.571429 0 1172 Tm 6.954839 0 Td 36.693548 Tz (TGTTGATTTTCGCCTAGGIGAAGCTAAGATCTACACCAATGGTATTGAGGGCCTTGATAG ) Tj 13.412903 0 Td 38.575269 Tz (2820 ) Tj 62.857143 0 0 62.857143 0 1124 Tm 9.8 0 Td 51.704545 Tz (IGITGANTTICGCCTAGGIGAAGCTAAGANCIACACCAATGGIATTGAGGGCCTIGATAG ) Tj 18.9 0 Td 50.378788 Tz (2820 ) Tj 61.428571 0 0 61.428571 0 885.142857 Tm 5.518605 0 Td 56.976744 Tz (MUT ) Tj 1.074419 0 Td 32.55814 Tz (- ) Tj 0.309302 0 Td 48.837209 Tz (1958 ) Tj 68.571429 0 0 68.571429 0 942 Tm 8.983333 0 Td 47.395833 Tz (ICHAATIGIIGAAAACAIGACCACCACAACAAACAAAACCAAAATGAICTICACATACAC ) Tj 17.325 0 Td 46.180556 Tz (2880 ) Tj 62.857143 0 0 62.857143 0 884 Tm 9.8 0 Td 51.704545 Tz (ICAAATTGTTGAAAACAIGACCACCACAACLAACAAAACCAAAAIGAICITCACATACAC ) Tj 18.9 0 Td 50.378788 Tz (2880 ) Tj 62.857143 0 0 62.857143 0 824 Tm 9.8 0 Td 51.704545 Tz (ICAAATIGITGAAAACAIGACCACCACHACAAACAAAACCAAAATGAICHICACATACAC ) Tj 18.9 0 Td 50.378788 Tz (2880 ) Tj 57.142857 0 0 57.142857 0 645 Tm 5.9675 0 Td 29.166667 Tz (R ) Tj 0.4025 0 Td 29.166667 Tz (- ) Tj 0.2625 0 Td 58.333333 Tz (NIL ) Tj 68.571429 0 0 68.571429 0 640 Tm 8.925 0 Td 47.638889 Tz (AAATACCGICCAGAGIACCIGGAGITCTACIGITTCAITGAAGATTGGCGICAAGACCAA ) Tj 17.383333 0 Td 46.180556 Tz (2000 ) Tj 1.3125 0 Td 24.305556 Tz (\( ) Tj 0.204167 0 Td 59.953704 Tz (SEQ ) Tj 1.254167 0 Td 48.611111 Tz (ID ) Tj 0.758333 0 Td 68.055556 Tz (NO ) Tj 0.904167 0 Td 9.722222 Tz (: ) Tj 0.2625 0 Td 43.75 Tz (22 ) Tj 0.583333 0 Td 24.305556 Tz (\) ) Tj 71.428571 0 0 71.428571 0 582 Tm 8.596 0 Td 45.577778 Tz (ALATACOGICCAGAGTACCIAGAGIICTACIGITICAITGAAGAYTGGCGICAAGACCAA ) Tj 16.66 0 Td 44.333333 Tz (2940 ) Tj 1.26 0 Td 23.333333 Tz (\( ) Tj 0.196 0 Td 57.555556 Tz (SEQ ) Tj 1.204 0 Td 46.666667 Tz (ID ) Tj 0.728 0 Td 65.333333 Tz (NO ) Tj 0.868 0 Td 9.333333 Tz (: ) Tj 0.252 0 Td 42 Tz (23 ) Tj 0.56 0 Td 23.333333 Tz (\) ) Tj 68.571429 0 0 68.571429 0 522 Tm 8.925 0 Td 47.638889 Tz (AAATACCGTCCAGACIACCIGGAGTICTACIGITTCATTGAAGATIGGCGICAAGACCAA ) Tj 17.383333 0 Td 46.180556 Tz (2940 ) Tj 1.3125 0 Td 24.305556 Tz (\( ) Tj 0.204167 0 Td 59.953704 Tz (SEQ ) Tj 1.283333 0 Td 46.180556 Tz (ID ) Tj 0.729167 0 Td 68.055556 Tz (NO ) Tj 0.904167 0 Td 9.722222 Tz (: ) Tj 0.2625 0 Td 46.180556 Tz (24 ) Tj 0.583333 0 Td 24.305556 Tz (\) ) Tj 61.428571 0 0 61.428571 0 468 Tm 13.674419 0 Td 54.94186 Tz (******** ) Tj 61.428571 0 0 61.428571 0 527 Tm 5.518605 0 Td 54.263566 Tz (MUT ) Tj 1.05814 0 Td 27.131783 Tz (- ) Tj 0.35814 0 Td 46.802326 Tz (1284 ) Tj 66.428571 0 0 66.428571 0 359.291045 Tm 16.724731 0 Td 48.088411 Tz (Figure ) Tj 1.866667 0 Td 47.670251 Tz (3 ) Tj ET Q endstream endobj 165 0 obj << /Length 1 >> stream q endstream endobj 166 0 obj << /Length 9918 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 95.714286 0 0 95.714286 0 3028.383234 Tm 3.374627 0 Td 55.721393 Tz (U.S. ) Tj 1.650746 0 Td 59.784411 Tz (Patent ) Tj 67.142857 0 0 67.142857 0 3023 Tm 12.570213 0 Td 53.782506 Tz (Jul ) Tj 1.012766 0 Td 19.858156 Tz (. ) Tj 0.357447 0 Td 59.574468 Tz (27 ) Tj 0.759574 0 Td 22.340426 Tz (, ) Tj 0.357447 0 Td 58.333333 Tz (2021 ) Tj 54.642857 0 0 54.642857 0 3031.326733 Tm 22.839216 0 Td 69.542484 Tz (Sheet ) Tj 2.415686 0 Td 67.102397 Tz (3 ) Tj 0.768627 0 Td 67.102397 Tz (of ) Tj 1.061438 0 Td 67.102397 Tz (4 ) Tj 80 0 0 80 0 3022 Tm 21.9 0 Td 75 Tz (US ) Tj 1.225 0 Td 53.333333 Tz (11,072,799 ) Tj 3.475 0 Td 66.666667 Tz (B2 ) Tj 41.428571 0 0 41.428571 0 2655 Tm 29.689655 0 Td 12.068966 Tz (. ) Tj 0.217241 0 Td 12.068966 Tz (: ) Tj 61.428571 0 0 61.428571 0 2679 Tm 5.583721 0 Td 32.55814 Tz (R ) Tj 0.423256 0 Td 32.55814 Tz (- ) Tj 0.227907 0 Td 49.741602 Tz (NIL ) Tj 61.904762 0 0 61.904762 0 2615 Tm 5.476154 0 Td 61.025641 Tz (MUT ) Tj 1.114615 0 Td 32.307692 Tz (- ) Tj 0.323077 0 Td 46.442308 Tz (1958 ) Tj 61.428571 0 0 61.428571 0 2551.551724 Tm 5.518605 0 Td 58.78553 Tz (MUT ) Tj 1.074419 0 Td 32.55814 Tz (- ) Tj 0.406977 0 Td 46.124031 Tz (1284 ) Tj 72.857143 0 0 72.857143 0 2674 Tm 8.55098 0 Td 45.217865 Tz (DGLVHVRCCYNNKYWAPQORLLHGSARHIIGTANELEEDLSKPSCTLIKHIPVSGEDGST ) Tj 16.580392 0 Td 38.888889 Tz (120 ) Tj 72.857143 0 0 72.857143 0 2607 Tm 8.537255 0 Td 45.341042 Tz (DGLVHVRCCYNNKYWAPQORILHGSARNTIGTANELEED ) Tj 10.65098 0 Td 45.206972 Tz (LSKPSCTLFKHIPVSGEDGST ) Tj 5.860784 0 Td 44.989107 Tz (120 ) Tj 42.857143 0 0 42.857143 0 2588 Tm 22.26 0 Td 54.444444 Tz (* ) Tj 68.571429 0 0 68.571429 0 2544 Tm 9.14375 0 Td 47.551638 Tz (DGLVHVRCCYNNKYWAPQORLLHGSARWTIGTANELEED ) Tj 11.24375 0 Td 48.148148 Tz (LSKPSCTLFKHIPVSGEDGST ) Tj 6.402083 0 Td 38.078704 Tz (120 ) Tj 41.428571 0 0 41.428571 0 2493 Tm 15.762069 0 Td 88.505747 Tz (********** ) Tj 41.428571 0 0 41.428571 0 2493 Tm 21.965517 0 Td 80.727969 Tz (*************** ) Tj 41.428571 0 0 41.428571 0 2493 Tm 39.344828 0 Td 91.020115 Tz (******** ) Tj 57.142857 0 0 57.142857 0 2349 Tm 5.9675 0 Td 29.166667 Tz (R ) Tj 0.4725 0 Td 29.166667 Tz (- ) Tj 0.1925 0 Td 58.333333 Tz (NIL ) Tj 64.761905 0 0 64.761905 0 2280.576159 Tm 5.25 0 Td 54.901961 Tz (MUT ) Tj 1.003676 0 Td 33.455882 Tz (- ) Tj 0.308824 0 Td 47.610294 Tz (1958 ) Tj 65.714286 0 0 65.714286 0 2213 Tm 5.173913 0 Td 52.415459 Tz (MUT ) Tj 1.019565 0 Td 30.434783 Tz (- ) Tj 0.319565 0 Td 43.75 Tz (1284 ) Tj 84.285714 0 0 84.285714 0 2333 Tm 7.427119 0 Td 39.015645 Tz (CRELASQIGKYACVLSSSDMSKHPYLHIAREESDQDNLLDAFTVLDVSEQMQ ) Tj 12.244068 0 Td 37.570621 Tz (LPSYLAFK ) Tj 2.1 0 Td 33.615819 Tz (180 ) Tj 74.285714 0 0 74.285714 0 2272 Tm 8.386538 0 Td 44.385684 Tz (CRELHSQIGKYACVISSSEMSKHPYLHIAREESDQONLLDAFTVLDVSEQMQLPSYLAFK ) Tj 16.315385 0 Td 39.636752 Tz (180 ) Tj 74.285714 0 0 74.285714 0 2206 Tm 8.386538 0 Td 43.684012 Tz (CRFLHSQLGKYACVISS ) Tj 4.563462 0 Td 43.899573 Tz (SEMSKHPYLHIAREESDQONLLDAFTVLDV ) Tj 8.076923 0 Td 42.973373 Tz (SEQMQLPSYLAFK ) Tj 3.688462 0 Td 34.401709 Tz (180 ) Tj 48.571429 0 0 48.571429 0 2253 Tm 21.432353 0 Td 72.058824 Tz (............ ) Tj 44.285714 0 0 44.285714 0 2159 Tm 14.045161 0 Td 65.860215 Tz (?? ) Tj 0.496774 0 Td 70.878136 Tz (****** ) Tj 42.857143 0 0 42.857143 0 2160 Tm 18.643333 0 Td 73.888889 Tz (***** ) Tj 21.428571 0 0 21.428571 0 2054 Tm 78.68 0 Td 73.888889 Tz (:: ) Tj 25.714286 0 0 25.714286 0 2053 Tm 68.327778 0 Td 77.777778 Tz (:::: ) Tj 25.238095 0 0 25.238095 0 1994.411765 Tm 62.207547 0 Td 19.811321 Tz (. ) Tj 0.277358 0 Td 75.943396 Tz (:: ) Tj 1.149057 0 Td 26.415094 Tz (.. ) Tj 55.714286 0 0 55.714286 0 1975 Tm 32.828205 0 Td 57.834758 Tz (nan ) Tj 57.142857 0 0 57.142857 0 2013 Tm 5.985 0 Td 35 Tz (R ) Tj 0.42 0 Td 35 Tz (- ) Tj 0.28 0 Td 56.388889 Tz (NIL ) Tj 61.428571 0 0 61.428571 0 1949.51049 Tm 5.518605 0 Td 60.594315 Tz (MUT ) Tj 1.106977 0 Td 32.55814 Tz (- ) Tj 0.439535 0 Td 43.410853 Tz (1958 ) Tj 61.428571 0 0 61.428571 0 1883.545455 Tm 5.518605 0 Td 58.78553 Tz (MUT ) Tj 1.106977 0 Td 32.55814 Tz (- ) Tj 0.406977 0 Td 44.767442 Tz (1284 ) Tj 62.857143 0 0 62.857143 0 2011 Tm 9.847727 0 Td 52.462121 Tz (GDNGRFLGAKIVEGYRYLEYSKDDIGDLSVLHTIFTNKDGWVRIKSNYFDMFWRRS ) Tj 17.738636 0 Td 53.030303 Tz (PNVI ) Tj 1.543182 0 Td 49.494949 Tz (240 ) Tj 42.857143 0 0 42.857143 0 1988.3 Tm 28.42 0 Td 45.37037 Tz (1.3 ) Tj 0.863333 0 Td 58.333333 Tz (. ) Tj 62.857143 0 0 62.857143 0 1950 Tm 9.927273 0 Td 52.28244 Tz (GONGRFLGAKIVEGYRYLEYSKDDIGDISTIHTIFTNKD ) Tj 12.234091 0 Td 53.030303 Tz (GVYRIKSNYEDMEFRRSPNHI ) Tj 6.920455 0 Td 49.494949 Tz (240 ) Tj 79.52381 0 0 79.52381 0 1870.749331 Tm 7.771257 0 Td 41.916168 Tz (GDNGRFLGAKIVEGYRYLEYSKDDIGDLSVLHTIFTNKDGVVRIKSNYFDME ) Tj 13.065269 0 Td 26.197605 Tz (-- ) Tj 2.137725 0 Td 39.121756 Tz (232 ) Tj 15.714286 0 0 15.714286 0 1868 Tm 116.263636 0 Td 79.545455 Tz (........ ) Tj 41.428571 0 0 41.428571 0 1826 Tm 29.472414 0 Td 109.961686 Tz (*** ) Tj 14.285714 0 0 14.285714 0 1656 Tm 68.53 0 Td 23.333333 Tz (, ) Tj 0.49 0 Td 11.666667 Tz (: ) Tj 0.21 0 Td 75.833333 Tz (.. ) Tj 57.619048 0 0 57.619048 0 1678.296296 Tm 5.952893 0 Td 34.710744 Tz (R ) Tj 0.416529 0 Td 34.710744 Tz (- ) Tj 0.22562 0 Td 54.958678 Tz (NIL ) Tj 62.857143 0 0 62.857143 0 1613 Tm 5.425 0 Td 53.914141 Tz (MUT ) Tj 1.05 0 Td 29.166667 Tz (- ) Tj 0.318182 0 Td 46.401515 Tz (1958 ) Tj 62.380952 0 0 62.380952 0 1546 Tm 5.450382 0 Td 52.544529 Tz (MUT ) Tj 0.993893 0 Td 42.748092 Tz (- ) Tj 0.336641 0 Td 49.427481 Tz (1284 ) Tj 62.857143 0 0 62.857143 0 1678 Tm 9.752273 0 Td 52.897727 Tz (WADSTDTTHNNRDTLFKVTTGPDFIALRNLGNNNECKRLTTEGKYDCLWAAVGSITAEVK ) Tj 19.377273 0 Td 49.494949 Tz (300 ) Tj 41.428571 0 0 41.428571 0 1653 Tm 14.724138 0 Td 16.091954 Tz (. ) Tj 45.714286 0 0 45.714286 0 1651 Tm 28.153125 0 Td 41.927083 Tz (.. ) Tj 65.714286 0 0 65.714286 0 1610 Tm 9.465217 0 Td 50.217391 Tz (WADSTDITHNNRDTLIKVITGPDFIALRNL ) Tj 9.03913 0 Td 47.554348 Tz (GNNN ) Tj 1.247826 0 Td 49.944259 Tz (FCKRLTTEGKYDCLNAAVGSITABVK ) Tj 8.065217 0 Td 47.342995 Tz (300 ) Tj 64.285714 0 0 64.285714 0 1546 Tm 28.42 0 Td 49.259259 Tz (232 ) Tj 30 0 0 30 0 1325 Tm 11.733333 0 Td 16.666667 Tz (. ) Tj 60 0 0 60 0 1343 Tm 5.716667 0 Td 33.333333 Tz (R ) Tj 0.35 0 Td 33.333333 Tz (- ) Tj 0.283333 0 Td 50.925926 Tz (NIL ) Tj 65.714286 0 0 65.714286 0 1276.114094 Tm 5.143478 0 Td 55.797101 Tz (MUT ) Tj 1.034783 0 Td 32.971014 Tz (- ) Tj 0.334783 0 Td 44.384058 Tz (1958 ) Tj 63.333333 0 0 63.333333 0 1211.567901 Tm 5.352632 0 Td 61.403509 Tz (MUT ) Tj 1.089474 0 Td 34.210526 Tz (- ) Tj 0.3 0 Td 51.973684 Tz (1284 ) Tj 75.714286 0 0 75.714286 0 1335 Tm 8.056604 0 Td 43.98847 Tz (MRCIEPIVSRDIYDVDFRIGEAKIYTNGIEGLDSQIVENMITTINKTKMIFTYTNTVQST ) Tj 16.166038 0 Td 38.888889 Tz (360 ) Tj 72.857143 0 0 72.857143 0 1270 Tm 8.372549 0 Td 45.675381 Tz (MRCIEPIVSRDIYDVDFRLGEAKIYTNGIEGLDSQIVENMITTINKIKMIFTYTNIVOST ) Tj 16.8 0 Td 39.651416 Tz (360 ) Tj 65.714286 0 0 65.714286 0 1211 Tm 27.771739 0 Td 49.879227 Tz (232 ) Tj 31.428571 0 0 31.428571 0 990 Tm 20.681818 0 Td 95.454545 Tz (. ) Tj 60 0 0 60 0 1008 Tm 5.716667 0 Td 33.333333 Tz (R ) Tj 0.35 0 Td 33.333333 Tz (- ) Tj 0.266667 0 Td 55.555556 Tz (NIL ) Tj 62.857143 0 0 62.857143 0 944 Tm 5.393182 0 Td 60.984848 Tz (MUT ) Tj 1.097727 0 Td 31.818182 Tz (- ) Tj 0.318182 0 Td 46.401515 Tz (1958 ) Tj 61.904762 0 0 61.904762 0 877.48 Tm 5.492308 0 Td 70 Tz (MUT ) Tj 1.340769 0 Td 37.692308 Tz (- ) Tj 0.242308 0 Td 39.038462 Tz (1284 ) Tj 14.285714 0 0 14.285714 0 960 Tm 44.8 0 Td 177.5 Tz (wwwwwwwwwwwwwwwwwwwwwwwwwwww ) Tj 12.857143 0 0 12.857143 0 960 Tm 108.033333 0 Td 234.259259 Tz (Wwwwwwwwwwwwww ) Tj 78.571429 0 0 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Tz (epi ) Tj 55.238095 0 0 55.238095 0 2352.46368 Tm 5.847414 0 Td 66.37931 Tz (ING ) Tj 1.828448 0 Td 64.87069 Tz (FHB1 ) Tj 2.262931 0 Td 66.982759 Tz (RESISTANCE ) Tj 4.652586 0 Td 72.413793 Tz (TO ) Tj 1.52069 0 Td 72.413793 Tz (FUSARIUM ) Tj 4.109483 0 Td 76.939655 Tz (HEAD ) Tj 3.258621 0 Td 53.706897 Tz (demic ) Tj 1.900862 0 Td 42.241379 Tz (in ) Tj 0.742241 0 Td 53.706897 Tz (wheat ) Tj 1.665517 0 Td 12.068966 Tz (. ) Tj 0.380172 0 Td 70.402299 Tz (FHB ) Tj 1.538793 0 Td 47.270115 Tz (not ) Tj 1.122414 0 Td 49.030172 Tz (only ) Tj 1.412069 0 Td 48.706897 Tz (reduces ) Tj 2.335345 0 Td 48.275862 Tz (crop ) Tj 1.430172 0 Td 47.672414 Tz (production ) Tj 2.914655 0 Td 30.172414 Tz (, ) Tj 0.434483 0 Td 30.172414 Tz (it ) Tj 56.031746 0 0 56.031746 0 2307.038585 Tm 5.764589 0 Td 66.926346 Tz (BLIGHT ) Tj 2.623513 0 Td 64.589235 Tz (DISEASE ) Tj 2.873371 0 Td 79.320113 Tz (AND ) Tj 1.624079 0 Td 66.926346 Tz (USES ) Tj 1.820397 0 Td 70.538244 Tz (THEREOF ) Tj 2.980453 0 Td 14.872521 Tz (, ) Tj 0.339093 0 Td 49.822946 Tz (each ) Tj 1.392068 0 Td 50.566572 Tz (of ) Tj 0.731728 0 Td 54.730878 Tz (which ) Tj 2.980453 0 Td 43.130312 Tz (also ) Tj 1.427762 0 Td 45.36119 Tz (severely ) Tj 2.552125 0 Td 40.368272 Tz (affects ) Tj 2.070255 0 Td 45.807365 Tz (grain ) Tj 1.713314 0 Td 43.767705 Tz (quality ) Tj 2.195184 0 Td 52.549575 Tz (due ) Tj 1.284986 0 Td 41.643059 Tz (to ) Tj 0.874504 0 Td 44.617564 Tz (the ) Tj 1.160057 0 Td 45.509915 Tz (associated ) Tj 60 0 0 60 0 2262.631741 Tm 5.4 0 Td 30.555556 Tz (is ) Tj 0.633333 0 Td 43.055556 Tz (incorporated ) Tj 3.333333 0 Td 50 Tz (by ) Tj 0.833333 0 Td 42.592593 Tz (reference ) Tj 2.533333 0 Td 38.888889 Tz (in ) Tj 0.7 0 Td 29.62963 Tz (its ) Tj 0.766667 0 Td 38.888889 Tz (entirety ) Tj 2.133333 0 Td 40.740741 Tz (herein ) Tj 1.55 0 Td 19.444444 Tz (. ) Tj 65.714286 0 0 65.714286 0 2268.26893 Tm 19.721739 0 Td 38.043478 Tz (toxins ) Tj 1.734783 0 Td 32.971014 Tz (\( ) Tj 0.182609 0 Td 38.325282 Tz (primarily ) Tj 2.404348 0 Td 59.601449 Tz (De ) Tj 0.7 0 Td 32.971014 Tz (- ) Tj 0.182609 0 Td 40.368357 Tz (oxynivalenol ) Tj 3.256522 0 Td 40.57971 Tz (or ) Tj 0.791304 0 Td 62.560386 Tz (DON ) Tj 1.263043 0 Td 25.362319 Tz (\) ) Tj 0.121739 0 Td 25.362319 Tz (. ) Tj 0.441304 0 Td 44.637681 Tz (There ) Tj 1.643478 0 Td 39.311594 Tz (thus ) Tj 61.428571 0 0 61.428571 0 2219.753477 Tm 21.113953 0 Td 37.5323 Tz (exists ) Tj 1.530233 0 Td 40.697674 Tz (a ) Tj 0.406977 0 Td 48.158915 Tz (need ) Tj 1.302326 0 Td 39.341085 Tz (in ) Tj 0.602326 0 Td 40.697674 Tz (the ) Tj 0.911628 0 Td 34.366925 Tz (art ) Tj 0.781395 0 Td 38.888889 Tz (for ) Tj 0.862791 0 Td 46.425495 Tz (improving ) Tj 2.669767 0 Td 40.697674 Tz (the ) Tj 0.87907 0 Td 39.883721 Tz (resistance ) Tj 2.572093 0 Td 44.767442 Tz (of ) Tj 0.634884 0 Td 39.793282 Tz (plants ) Tj 47.142857 0 0 47.142857 0 2182 Tm 8.781818 0 Td 84.062851 Tz (FEDERALLY ) Tj 4.815152 0 Td 84.455668 Tz (SPONSORED ) Tj 4.857576 0 Td 85.732323 Tz (RESEARCH ) Tj 4.412121 0 Td 90.151515 Tz (OR ) Tj 62.857143 0 0 62.857143 0 2177.097463 Tm 20.618182 0 Td 35.795455 Tz (to ) Tj 0.747727 0 Td 61.868687 Tz (FHB ) Tj 1.177273 0 Td 13.257576 Tz (, ) Tj 0.381818 0 Td 37.784091 Tz (particularly ) Tj 3.006818 0 Td 47.727273 Tz (wheat ) Tj 1.415909 0 Td 23.863636 Tz (, ) Tj 0.413636 0 Td 41.098485 Tz (barley ) Tj 1.765909 0 Td 47.727273 Tz (and ) Tj 1.129545 0 Td 40.30303 Tz (other ) Tj 1.511364 0 Td 40.833333 Tz (small ) Tj 1.527273 0 Td 40.833333 Tz (grain ) Tj 48.571429 0 0 48.571429 0 2138 Tm 13.052941 0 Td 85.472371 Tz (DEVELOPMENT ) Tj 55.857143 0 0 55.857143 0 2136.984081 Tm 22.253197 0 Td 40.28133 Tz (20 ) Tj 0.948849 0 Td 47.740835 Tz (crops ) Tj 1.450128 0 Td 20.886616 Tz (. ) Tj 0.375959 0 Td 56.692242 Tz (The ) Tj 1.253197 0 Td 45.609548 Tz (present ) Tj 2.16624 0 Td 46.746235 Tz (invention ) Tj 2.757033 0 Td 46.746235 Tz (addresses ) Tj 2.774936 0 Td 41.773231 Tz (that ) Tj 1.217391 0 Td 52.962489 Tz (need ) Tj 1.324808 0 Td 11.935209 Tz (. ) Tj 32.857143 0 0 32.857143 0 2340 Tm 37.86087 0 Td 65.942029 Tz (15 ) Tj 17.142857 0 0 17.142857 0 1643 Tm 55.708333 0 Td 68.055556 Tz (?? ) Tj 59.464286 0 0 59.464286 0 2046.435897 Tm 6.070871 0 Td 44.144144 Tz (This ) Tj 1.278078 0 Td 43.910577 Tz (invention ) Tj 2.539339 0 Td 52.318986 Tz (was ) Tj 1.143544 0 Td 56.056056 Tz (made ) Tj 1.53033 0 Td 46.946947 Tz (with ) Tj 1.311712 0 Td 49.60961 Tz (government ) Tj 3.195195 0 Td 44.044044 Tz (support ) Tj 2.018018 0 Td 48.208208 Tz (under ) Tj 48.571429 0 0 48.571429 0 2058 Tm 30.285294 0 Td 92.647059 Tz (SUMMARY ) Tj 4.138235 0 Td 77.205882 Tz (OF ) Tj 1.235294 0 Td 80.065359 Tz (THE ) Tj 1.75 0 Td 77.777778 Tz (INVENTION ) Tj 52.857143 0 0 52.857143 0 2003 Tm 6.110811 0 Td 46.903153 Tz (contract ) Tj 2.478378 0 Td 57.207207 Tz (numbers ) Tj 2.667568 0 Td 53.603604 Tz (59-0206-2-088 ) Tj 4.256757 0 Td 15.765766 Tz (, ) Tj 0.378378 0 Td 53.361053 Tz (59-0790-9-025 ) Tj 4.256757 0 Td 15.765766 Tz (, ) Tj 0.359459 0 Td 61.261261 Tz (59-0790 ) Tj 59.831933 0 0 59.831933 0 1963.467054 Tm 5.398455 0 Td 45.683521 Tz (4-091 ) Tj 1.470787 0 Td 13.927903 Tz (, ) Tj 0.534831 0 Td 49.211923 Tz (and ) Tj 1.286938 0 Td 49.444054 Tz (2004-35300-14787 ) Tj 4.813483 0 Td 13.927903 Tz (, ) Tj 0.534831 0 Td 50.140449 Tz (awarded ) Tj 2.490309 0 Td 50.140449 Tz (by ) Tj 1.002809 0 Td 42.712235 Tz (the ) Tj 1.15323 0 Td 47.819132 Tz (United ) Tj 3.610112 0 Td 53.854557 Tz (The ) Tj 1.10309 0 Td 42.181648 Tz (present ) Tj 1.972191 0 Td 42.712235 Tz (invention ) Tj 2.473596 0 Td 43.872893 Tz (provides ) Tj 2.273034 0 Td 40.770769 Tz (genetically ) Tj 2.807865 0 Td 27.855805 Tz (- ) Tj 0.083567 0 Td 47.006671 Tz (modified ) Tj 2.423455 0 Td 41.226592 Tz (plant ) Tj 64.210526 0 0 64.210526 0 1919.310945 Tm 5.030328 0 Td 37.204007 Tz (States ) Tj 1.604098 0 Td 45.68306 Tz (Department ) Tj 2.990164 0 Td 44.125683 Tz (of ) Tj 0.669672 0 Td 40.350224 Tz (Agriculture ) Tj 2.631967 0 Td 25.956284 Tz (. ) Tj 0.436066 0 Td 48.45173 Tz (The ) Tj 1.121311 0 Td 44.125683 Tz (United ) Tj 1.853279 0 Td 36.771403 Tz (States ) Tj 1.604098 0 Td 42.827869 Tz (gov- ) Tj 1.417213 0 Td 33.743169 Tz (25 ) Tj 0.82541 0 Td 34.262295 Tz (cells ) Tj 1.214754 0 Td 44.125683 Tz (having ) Tj 1.77541 0 Td 40.664845 Tz (increased ) Tj 2.367213 0 Td 37.896175 Tz (resistance ) Tj 2.460656 0 Td 35.040984 Tz (to ) Tj 0.638525 0 Td 60.564663 Tz (FHB ) Tj 1.308197 0 Td 39.30523 Tz (disease ) Tj 1.837705 0 Td 36.014344 Tz (relative ) Tj 1.915574 0 Td 35.040984 Tz (to ) Tj 57.142857 0 0 57.142857 0 1872.156794 Tm 5.6525 0 Td 50.416667 Tz (ernment ) Tj 2.345 0 Td 46.666667 Tz (has ) Tj 1.1025 0 Td 42.5 Tz (certain ) Tj 1.995 0 Td 40.347222 Tz (rights ) Tj 1.715 0 Td 42.291667 Tz (in ) Tj 0.7175 0 Td 43.75 Tz (the ) Tj 1.0325 0 Td 45.046296 Tz (invention ) Tj 2.52 0 Td 20.416667 Tz (. ) Tj 62.857143 0 0 62.857143 0 1876.944149 Tm 20.634091 0 Td 39.772727 Tz (a ) Tj 0.509091 0 Td 39.393939 Tz (control ) Tj 1.909091 0 Td 39.772727 Tz (plant ) Tj 1.463636 0 Td 33.806818 Tz (cell ) Tj 0.890909 0 Td 10.606061 Tz (. ) Tj 0.35 0 Td 41.098485 Tz (In ) Tj 0.763636 0 Td 50.378788 Tz (some ) Tj 1.479545 0 Td 48.450413 Tz (embodiments ) Tj 3.181818 0 Td 23.863636 Tz (, ) Tj 0.429545 0 Td 39.772727 Tz (a ) Tj 0.620455 0 Td 41.219008 Tz (genetically ) Tj 61.964286 0 0 61.964286 0 1835.32937 Tm 20.915274 0 Td 44.716619 Tz (modified ) Tj 2.259366 0 Td 40.345821 Tz (plant ) Tj 1.35562 0 Td 44.380403 Tz (of ) Tj 0.597118 0 Td 41.242395 Tz (the ) Tj 0.887608 0 Td 41.840111 Tz (invention ) Tj 2.388473 0 Td 44.82869 Tz (comprises ) Tj 2.582133 0 Td 46.920696 Tz (exogenous ) Tj 2.678963 0 Td 41.114313 Tz (nucleic ) Tj 60.714286 0 0 60.714286 0 1790.288235 Tm 9.8 0 Td 66.568627 Tz (SEQUENCE ) Tj 3.409412 0 Td 57.254902 Tz (LISTING ) Tj 62.571429 0 0 62.571429 0 1789.952255 Tm 20.712329 0 Td 41.286149 Tz (acid ) Tj 1.262557 0 Td 44.94863 Tz (encoding ) Tj 2.461187 0 Td 39.954338 Tz (a ) Tj 0.511416 0 Td 40.334855 Tz (protein ) Tj 1.726027 0 Td 13.318113 Tz (, ) Tj 0.399543 0 Td 39.954338 Tz (or ) Tj 0.751142 0 Td 44.689667 Tz (conserved ) Tj 2.700913 0 Td 49.277017 Tz (domain ) Tj 2.045662 0 Td 41.286149 Tz (or ) Tj 0.751142 0 Td 41.09589 Tz (residue ) Tj 55.714286 0 0 55.714286 0 1748 Tm 23.261538 0 Td 46.581197 Tz (thereof ) Tj 1.884615 0 Td 26.923077 Tz (, ) Tj 0.376923 0 Td 55.042735 Tz (which ) Tj 1.866667 0 Td 45.726496 Tz (confers ) Tj 2.153846 0 Td 43.974359 Tz (resistance ) Tj 2.835897 0 Td 41.880342 Tz (to ) Tj 0.735897 0 Td 69.80057 Tz (FHB ) Tj 1.346154 0 Td 11.965812 Tz (. ) Tj 0.323077 0 Td 46.367521 Tz (In ) Tj 0.789744 0 Td 56.837607 Tz (some ) Tj 1.669231 0 Td 60.826211 Tz (embodi ) Tj 63.857143 0 0 63.857143 0 1706.063802 Tm 5.637584 0 Td 48.719861 Tz (The ) Tj 1.096197 0 Td 41.759881 Tz (following ) Tj 2.489933 0 Td 39.149888 Tz (application ) Tj 2.803132 0 Td 39.802386 Tz (contains ) Tj 2.145414 0 Td 39.149888 Tz (a ) Tj 0.485459 0 Td 43.717375 Tz (sequence ) Tj 2.333333 0 Td 34.302759 Tz (listing ) Tj 1.659955 0 Td 37.844892 Tz (in ) Tj 0.814318 0 Td 35.234899 Tz (30 ) Tj 0.814318 0 Td 45.41387 Tz (ments ) Tj 1.378076 0 Td 20.87994 Tz (, ) Tj 0.438479 0 Td 38.49739 Tz (said ) Tj 1.174497 0 Td 45.819869 Tz (exogenous ) Tj 2.740492 0 Td 39.522744 Tz (nucleic ) Tj 1.957494 0 Td 39.802386 Tz (acid ) Tj 1.221477 0 Td 43.997017 Tz (encodes ) Tj 2.129754 0 Td 39.149888 Tz (a ) Tj 0.485459 0 Td 36.912752 Tz (protein ) Tj 1.612975 0 Td 26.099925 Tz (, ) Tj 0.454139 0 Td 40.454884 Tz (or ) Tj 58.695652 0 0 58.695652 0 1662.678707 Tm 5.485926 0 Td 50.046296 Tz (computer ) Tj 2.572593 0 Td 44.722222 Tz (readable ) Tj 2.368148 0 Td 46.378601 Tz (format ) Tj 1.891111 0 Td 28.395062 Tz (\( ) Tj 0.204444 0 Td 64.36214 Tz (CRF ) Tj 1.192593 0 Td 28.395062 Tz (\) ) Tj 0.238519 0 Td 14.197531 Tz (, ) Tj 0.340741 0 Td 46.0631 Tz (submitted ) Tj 2.674815 0 Td 41.17284 Tz (as ) Tj 0.715556 0 Td 42.592593 Tz (a ) Tj 0.46 0 Td 39.04321 Tz (text ) Tj 1.158519 0 Td 32.654321 Tz (file ) Tj 0.988148 0 Td 41.17284 Tz (in ) Tj 1.805926 0 Td 47.640604 Tz (conserved ) Tj 2.794074 0 Td 52.530864 Tz (domain ) Tj 2.112593 0 Td 42.592593 Tz (or ) Tj 0.715556 0 Td 43.40388 Tz (residue ) Tj 2.044444 0 Td 45.432099 Tz (thereof ) Tj 1.771852 0 Td 25.555556 Tz (, ) Tj 0.391852 0 Td 52.246914 Tz (which ) Tj 1.771852 0 Td 43.809524 Tz (confers ) Tj 2.061481 0 Td 45.432099 Tz (type ) Tj 1.311852 0 Td 45.432099 Tz (2 ) Tj 62.685714 0 0 62.685714 0 1619.682345 Tm 5.136737 0 Td 51.048314 Tz (ASCII ) Tj 1.770738 0 Td 43.426517 Tz (format ) Tj 1.770738 0 Td 37.222729 Tz (entitled ) Tj 1.978122 0 Td 26.587663 Tz ( ) Tj 0.350957 0 Td 45.531373 Tz (Sequence ) Tj 2.39289 0 Td 42.540261 Tz (Listing ) Tj 1.834549 0 Td 15.952598 Tz (, ) Tj 0.143573 0 Td 15.952598 Tz ( ) Tj 0.319052 0 Td 40.641143 Tz (created ) Tj 1.914312 0 Td 47.857794 Tz (on ) Tj 0.781677 0 Td 59.379115 Tz (May ) Tj 2.281222 0 Td 39.083865 Tz (resistance ) Tj 2.52051 0 Td 35.893345 Tz (to ) Tj 0.638104 0 Td 62.037881 Tz (FHB ) Tj 1.324066 0 Td 47.857794 Tz (and ) Tj 0.877393 0 Td 21.270131 Tz (/ ) Tj 0.159526 0 Td 39.881495 Tz (or ) Tj 0.622151 0 Td 42.540261 Tz (type ) Tj 1.260255 0 Td 26.587663 Tz (1 ) Tj 0.398815 0 Td 39.083865 Tz (resistance ) Tj 2.504558 0 Td 37.222729 Tz (to ) Tj 0.654057 0 Td 61.151626 Tz (FHB ) Tj 1.180492 0 Td 10.635065 Tz (. ) Tj 0.287147 0 Td 39.881495 Tz (In ) Tj 0.670009 0 Td 51.181252 Tz (some ) Tj 60.514286 0 0 60.514286 0 1577.586088 Tm 5.337583 0 Td 48.197986 Tz (27 ) Tj 0.644476 0 Td 13.770853 Tz (, ) Tj 0.313975 0 Td 48.886528 Tz (2015 ) Tj 1.239377 0 Td 13.770853 Tz (, ) Tj 0.3305 0 Td 38.558388 Tz (as ) Tj 0.677526 0 Td 48.197986 Tz (29 ) Tj 0.809726 0 Td 67.47718 Tz (KB ) Tj 0.892351 0 Td 11.016682 Tz (. ) Tj 0.280925 0 Td 51.411185 Tz (The ) Tj 1.140227 0 Td 42.886371 Tz (content ) Tj 1.999528 0 Td 45.443815 Tz (of ) Tj 0.677526 0 Td 41.312559 Tz (the ) Tj 0.941926 0 Td 62.427867 Tz (CRF ) Tj 1.338527 0 Td 36.355052 Tz (filed ) Tj 1.288952 0 Td 30.295877 Tz (is ) Tj 0.561851 0 Td 46.8209 Tz (hereby ) Tj 2.957979 0 Td 49.324692 Tz (embodiments ) Tj 3.32153 0 Td 24.787535 Tz (, ) Tj 0.561851 0 Td 39.935474 Tz (said ) Tj 1.355052 0 Td 48.044976 Tz (exogenous ) Tj 2.991029 0 Td 42.099465 Tz (nucleic ) Tj 2.181303 0 Td 42.689644 Tz (acid ) Tj 1.404627 0 Td 31.672962 Tz (is ) Tj 0.793201 0 Td 48.197986 Tz (an ) Tj 0.958451 0 Td 48.886528 Tz (Fhbl ) Tj 60.357143 0 0 60.357143 0 1539.431646 Tm 5.351479 0 Td 43.261012 Tz (incorporated ) Tj 3.313609 0 Td 51.084813 Tz (by ) Tj 0.811834 0 Td 43.261012 Tz (reference ) Tj 2.319527 0 Td 19.329389 Tz (. ) Tj 0.364497 0 Td 50.394477 Tz (Only ) Tj 1.424852 0 Td 48.783695 Tz (one ) Tj 1.110059 0 Td 41.420118 Tz (strand ) Tj 1.706509 0 Td 45.56213 Tz (of ) Tj 0.712426 0 Td 46.942801 Tz (each ) Tj 1.308876 0 Td 42.209073 Tz (nucleic ) Tj 3.048521 0 Td 41.814596 Tz (nucleic ) Tj 1.95503 0 Td 42.110454 Tz (acid ) Tj 1.043787 0 Td 13.806706 Tz (, ) Tj 0.281657 0 Td 41.420118 Tz (or ) Tj 0.646154 0 Td 41.420118 Tz (a ) Tj 0.414201 0 Td 38.658777 Tz (plurality ) Tj 2.253254 0 Td 46.942801 Tz (of ) Tj 0.662722 0 Td 42.800789 Tz (copies ) Tj 1.723077 0 Td 46.942801 Tz (of ) Tj 0.662722 0 Td 46.942801 Tz (an ) Tj 0.712426 0 Td 49.704142 Tz (Fhbl ) Tj 1.408284 0 Td 41.814596 Tz (nucleic ) Tj 1.938462 0 Td 42.800789 Tz (acid ) Tj 1.060355 0 Td 13.806706 Tz (, ) Tj 63.714286 0 0 63.714286 0 1497.408575 Tm 5.053812 0 Td 40.54559 Tz (acid ) Tj 1.23991 0 Td 43.815396 Tz (sequence ) Tj 2.38565 0 Td 28.77429 Tz (is ) Tj 0.643498 0 Td 50.224215 Tz (shown ) Tj 1.538117 0 Td 13.079223 Tz (, ) Tj 0.360987 0 Td 40.981565 Tz (but ) Tj 0.988789 0 Td 39.237668 Tz (the ) Tj 0.973094 0 Td 46.481545 Tz (complementary ) Tj 3.908072 0 Td 39.237668 Tz (strand ) Tj 1.663677 0 Td 30.082212 Tz (is ) Tj 0.753363 0 Td 34.005979 Tz (35 ) Tj 0.816143 0 Td 40.022422 Tz (preferably ) Tj 2.589686 0 Td 44.469357 Tz (an ) Tj 0.706278 0 Td 45.631955 Tz (exogenous ) Tj 2.652466 0 Td 39.61136 Tz (nucleic ) Tj 1.867713 0 Td 39.237668 Tz (acid ) Tj 1.11435 0 Td 36.621824 Tz (that ) Tj 1.05157 0 Td 44.095665 Tz (encodes ) Tj 2.056054 0 Td 39.237668 Tz (a ) Tj 0.392377 0 Td 39.61136 Tz (protein ) Tj 61.942857 0 0 61.942857 0 1455.143795 Tm 5.198339 0 Td 44.933887 Tz (understood ) Tj 2.954336 0 Td 37.669127 Tz (as ) Tj 0.74262 0 Td 43.050431 Tz (included ) Tj 2.324723 0 Td 48.431734 Tz (by ) Tj 0.855627 0 Td 47.53485 Tz (any ) Tj 1.11393 0 Td 41.256663 Tz (reference ) Tj 2.486162 0 Td 37.669127 Tz (to ) Tj 0.726476 0 Td 40.359779 Tz (the ) Tj 1.000923 0 Td 42.751469 Tz (displayed ) Tj 3.535517 0 Td 44.933887 Tz (comprising ) Tj 2.857472 0 Td 41.256663 Tz (the ) Tj 0.920203 0 Td 48.969865 Tz (amino ) Tj 1.678967 0 Td 41.705105 Tz (acid ) Tj 1.178506 0 Td 45.404751 Tz (sequence ) Tj 2.373155 0 Td 44.395756 Tz (of ) Tj 0.678044 0 Td 60.98811 Tz (SEQ ) Tj 1.291513 0 Td 49.77706 Tz (ID ) Tj 0.774908 0 Td 71.302276 Tz (NO ) Tj 0.920203 0 Td 10.762608 Tz (: ) Tj 0.145295 0 Td 40.359779 Tz (3 ) Tj 0.306734 0 Td 13.45326 Tz (, ) Tj 0.306734 0 Td 43.050431 Tz (7 ) Tj 0.322878 0 Td 13.45326 Tz (, ) Tj 0.306734 0 Td 40.359779 Tz (8 ) Tj 0.306734 0 Td 13.45326 Tz (, ) Tj 58.690476 0 0 58.690476 0 1414.267894 Tm 5.520487 0 Td 42.123056 Tz (strand ) Tj 1.550507 0 Td 19.878296 Tz (. ) Tj 0.391886 0 Td 53.00879 Tz (The ) Tj 1.243813 0 Td 47.920892 Tz (sequence ) Tj 2.555781 0 Td 48.275862 Tz (of ) Tj 0.766734 0 Td 42.596349 Tz (the ) Tj 1.039351 0 Td 50.46029 Tz (complementary ) Tj 4.225558 0 Td 42.596349 Tz (strand ) Tj 1.789047 0 Td 48.275862 Tz (can ) Tj 1.107505 0 Td 49.69574 Tz (be ) Tj 1.891278 0 Td 44.016227 Tz (or ) Tj 0.81785 0 Td 42.596349 Tz (9 ) Tj 0.340771 0 Td 14.198783 Tz (; ) Tj 0.425963 0 Td 42.596349 Tz (or ) Tj 0.800811 0 Td 42.596349 Tz (a ) Tj 0.545233 0 Td 43.002028 Tz (protein ) Tj 2.078702 0 Td 48.275862 Tz (having ) Tj 2.044625 0 Td 35.496957 Tz (at ) Tj 0.732657 0 Td 38.052738 Tz (least ) Tj 1.448276 0 Td 46.004057 Tz (about ) Tj 1.686815 0 Td 51.115619 Tz (70 ) Tj 0.630426 0 Td 82.352941 Tz (% ) Tj 0.81785 0 Td 51.68357 Tz (amino ) Tj 1.874239 0 Td 43.306288 Tz (acid ) Tj 59.100529 0 0 59.100529 0 1372.207739 Tm 5.465264 0 Td 49.955237 Tz (deduced ) Tj 2.301164 0 Td 40.890779 Tz (as ) Tj 0.710654 0 Td 42.300806 Tz (the ) Tj 0.964458 0 Td 43.5094 Tz (reverse ) Tj 2.047359 0 Td 51.888988 Tz (complement ) Tj 3.333303 0 Td 46.530886 Tz (of ) Tj 0.710654 0 Td 42.300806 Tz (the ) Tj 0.964458 0 Td 46.883393 Tz (provided ) Tj 2.470367 0 Td 39.480752 Tz (strand ) Tj 1.55667 0 Td 19.740376 Tz (. ) Tj 1.421307 0 Td 39.833259 Tz (identity ) Tj 2.165801 0 Td 47.2359 Tz (with ) Tj 1.404387 0 Td 63.921218 Tz (SEQ ) Tj 1.421307 0 Td 53.581021 Tz (ID ) Tj 0.913697 0 Td 74.731423 Tz (NO ) Tj 0.964458 0 Td 11.280215 Tz (: ) Tj 0.389167 0 Td 42.300806 Tz (3 ) Tj 0.321486 0 Td 14.100269 Tz (, ) Tj 0.389167 0 Td 45.120859 Tz (7 ) Tj 0.338406 0 Td 14.100269 Tz (, ) Tj 0.406088 0 Td 42.300806 Tz (8 ) Tj 0.321486 0 Td 14.100269 Tz (, ) Tj 0.389167 0 Td 43.710833 Tz (or ) Tj 0.795255 0 Td 42.300806 Tz (9 ) Tj 0.54145 0 Td 49.820949 Tz (and ) Tj 1.150582 0 Td 41.360788 Tz (retaining ) Tj 2.487287 0 Td 43.240824 Tz (the ) Tj 60.496894 0 0 60.496894 0 1329.934567 Tm 5.355647 0 Td 62.445813 Tz (SEQ ) Tj 1.338912 0 Td 52.344285 Tz (ID ) Tj 0.826489 0 Td 73.006502 Tz (NO ) Tj 0.942197 0 Td 11.019849 Tz (: ) Tj 0.198357 0 Td 27.549624 Tz (1 ) Tj 0.446304 0 Td 30.304586 Tz (is ) Tj 0.595072 0 Td 41.324435 Tz (the ) Tj 0.958727 0 Td 47.523101 Tz (gene ) Tj 1.371971 0 Td 46.48999 Tz (sequence ) Tj 2.446407 0 Td 45.456879 Tz (of ) Tj 0.694251 0 Td 49.589322 Tz (Fhbl ) Tj 1.47115 0 Td 48.900582 Tz (gene ) Tj 1.206674 0 Td 19.284736 Tz (; ) Tj 0.347125 0 Td 61.527493 Tz (SEQ ) Tj 1.338912 0 Td 50.966804 Tz (ID ) Tj 1.900924 0 Td 41.048939 Tz (functional ) Tj 2.760472 0 Td 38.936801 Tz (characteristics ) Tj 3.801848 0 Td 45.456879 Tz (of ) Tj 0.74384 0 Td 41.324435 Tz (the ) Tj 1.024846 0 Td 41.718001 Tz (protein ) Tj 2.000103 0 Td 46.3752 Tz (having ) Tj 1.933984 0 Td 42.242756 Tz (the ) Tj 1.041376 0 Td 49.589322 Tz (amino ) Tj 68.571429 0 0 68.571429 0 1286.374486 Tm 4.695833 0 Td 64.409722 Tz (NO ) Tj 0.83125 0 Td 9.722222 Tz (: ) Tj 0.102083 0 Td 43.75 Tz (2 ) Tj 0.525 0 Td 26.736111 Tz (is ) Tj 0.56875 0 Td 36.458333 Tz (the ) Tj 0.904167 0 Td 58.940972 Tz (cDNA ) Tj 1.647917 0 Td 42.534722 Tz (sequence ) Tj 2.202083 0 Td 34.837963 Tz (for ) Tj 0.845833 0 Td 37.268519 Tz (the ) Tj 0.91875 0 Td 43.142361 Tz (Fhbl ) Tj 1.341667 0 Td 43.142361 Tz (gene ) Tj 0.947917 0 Td 29.166667 Tz (. ) Tj 0.466667 0 Td 57.523148 Tz (SEQ ) Tj 1.239583 0 Td 44.965278 Tz (ID ) Tj 0.889583 0 Td 34.027778 Tz (40 ) Tj 0.7875 0 Td 37.673611 Tz (acid ) Tj 1.09375 0 Td 41.015625 Tz (sequence ) Tj 2.172917 0 Td 40.104167 Tz (of ) Tj 0.641667 0 Td 54.282407 Tz (SEQ ) Tj 1.195833 0 Td 44.965278 Tz (ID ) Tj 0.729167 0 Td 64.409722 Tz (NO ) Tj 0.83125 0 Td 9.722222 Tz (: ) Tj 0.116667 0 Td 36.458333 Tz (3 ) Tj 0.291667 0 Td 12.152778 Tz (, ) Tj 0.30625 0 Td 38.888889 Tz (7 ) Tj 0.277083 0 Td 12.152778 Tz (, ) Tj 0.320833 0 Td 36.458333 Tz (8 ) Tj 0.2625 0 Td 12.152778 Tz (, ) Tj 0.30625 0 Td 37.673611 Tz (or ) Tj 0.641667 0 Td 36.458333 Tz (9 ) Tj 0.277083 0 Td 12.152778 Tz (, ) Tj 0.291667 0 Td 31.597222 Tz (e.g. ) Tj 0.802083 0 Td 14.583333 Tz (, ) Tj 0.291667 0 Td 36.458333 Tz (the ) Tj 0.845833 0 Td 32.638889 Tz (ability ) Tj 62.171429 0 0 62.171429 0 1245.322559 Tm 5.179228 0 Td 61.657475 Tz (NO ) Tj 0.948989 0 Td 18.765319 Tz (: ) Tj 0.225184 0 Td 21.446078 Tz (3 ) Tj 0.386029 0 Td 26.807598 Tz (is ) Tj 0.514706 0 Td 40.211397 Tz (the ) Tj 0.91682 0 Td 48.253676 Tz (478 ) Tj 1.077665 0 Td 48.789828 Tz (amino ) Tj 1.672794 0 Td 40.211397 Tz (acid ) Tj 1.206342 0 Td 42.221967 Tz (long ) Tj 1.190257 0 Td 39.828431 Tz (protein ) Tj 1.914062 0 Td 44.902727 Tz (sequence ) Tj 2.348346 0 Td 45.572917 Tz (of ) Tj 0.675551 0 Td 51.604626 Tz (Fhbl ) Tj 1.254596 0 Td 18.765319 Tz (. ) Tj 1.335018 0 Td 36.190257 Tz (to ) Tj 0.788143 0 Td 42.445364 Tz (confer ) Tj 1.817555 0 Td 39.407169 Tz (resistance ) Tj 2.670037 0 Td 36.190257 Tz (to ) Tj 0.772059 0 Td 62.551062 Tz (FHB ) Tj 1.206342 0 Td 10.723039 Tz (. ) Tj 0.418199 0 Td 40.211397 Tz (In ) Tj 0.804228 0 Td 51.604626 Tz (some ) Tj 1.560202 0 Td 49.472204 Tz (embodiments ) Tj 3.249081 0 Td 24.126838 Tz (, ) Tj 0.418199 0 Td 41.104984 Tz (the ) Tj 59.006211 0 0 59.006211 0 1207.37874 Tm 5.490947 0 Td 64.023392 Tz (SEQ ) Tj 1.372737 0 Td 52.254386 Tz (ID ) Tj 0.830421 0 Td 74.850877 Tz (NO ) Tj 0.966 0 Td 11.298246 Tz (: ) Tj 0.152526 0 Td 45.192982 Tz (4 ) Tj 0.508421 0 Td 31.070175 Tz (is ) Tj 0.593158 0 Td 42.368421 Tz (the ) Tj 0.966 0 Td 32.2 Tz (first ) Tj 1.186316 0 Td 47.389864 Tz (conserved ) Tj 2.728526 0 Td 43.175439 Tz (nucleic ) Tj 2.033684 0 Td 43.780702 Tz (acid ) Tj 1.254105 0 Td 52.254386 Tz (domain ) Tj 2.084526 0 Td 48.017544 Tz (of ) Tj 1.796421 0 Td 42.77193 Tz (protein ) Tj 1.982842 0 Td 45.192982 Tz (has ) Tj 1.050737 0 Td 42.085965 Tz (antifungal ) Tj 2.762421 0 Td 38.484649 Tz (activity ) Tj 1.813368 0 Td 28.245614 Tz (, ) Tj 0.389789 0 Td 36.013158 Tz (e.g. ) Tj 0.932105 0 Td 14.122807 Tz (, ) Tj 0.338947 0 Td 42.085965 Tz (antifungal ) Tj 2.745474 0 Td 39.190789 Tz (activity ) Tj 2.084526 0 Td 46.605263 Tz (with ) Tj 59.821429 0 0 59.821429 0 1166.190378 Tm 5.36597 0 Td 41.791045 Tz (the ) Tj 1.019701 0 Td 45.412935 Tz (Agglutinin ) Tj 3.042388 0 Td 44.070556 Tz (superfamily ) Tj 2.875224 0 Td 27.860697 Tz (. ) Tj 0.518209 0 Td 62.222222 Tz (SEQ ) Tj 1.454328 0 Td 51.542289 Tz (ID ) Tj 0.936119 0 Td 73.830846 Tz (NO ) Tj 0.952836 0 Td 11.144279 Tz (: ) Tj 0.150448 0 Td 39.004975 Tz (5 ) Tj 0.585075 0 Td 30.646766 Tz (is ) Tj 0.685373 0 Td 41.791045 Tz (the ) Tj 1.086567 0 Td 47.827529 Tz (second ) Tj 2.975522 0 Td 42.189055 Tz (respect ) Tj 2.039403 0 Td 37.61194 Tz (to ) Tj 0.768955 0 Td 41.791045 Tz (a ) Tj 0.568358 0 Td 41.393035 Tz (species ) Tj 2.056119 0 Td 45.970149 Tz (of ) Tj 0.752239 0 Td 45.970149 Tz (Fusarium ) Tj 2.440597 0 Td 25.074627 Tz (, ) Tj 0.451343 0 Td 34.825871 Tz (e.g. ) Tj 0.919403 0 Td 13.930348 Tz (, ) Tj 0.401194 0 Td 41.791045 Tz (a ) Tj 0.568358 0 Td 41.393035 Tz (species ) Tj 2.072836 0 Td 41.094527 Tz (selected ) Tj 59.849624 0 0 59.849624 0 1123.682759 Tm 5.396859 0 Td 46.722036 Tz (conserved ) Tj 2.706784 0 Td 42.169179 Tz (nucleic ) Tj 1.988317 0 Td 43.163735 Tz (acid ) Tj 1.219724 0 Td 51.982133 Tz (domain ) Tj 2.055151 0 Td 47.340871 Tz (of ) Tj 0.68505 0 Td 41.771357 Tz (the ) Tj 0.91897 0 Td 45.113065 Tz (Agglutinin ) Tj 2.974121 0 Td 44.865531 Tz (superfam- ) Tj 3.726005 0 Td 50.125628 Tz (from ) Tj 1.704271 0 Td 36.201843 Tz (F. ) Tj 1.019221 0 Td 48.269123 Tz (avenaceum ) Tj 2.823744 0 Td 16.708543 Tz (, ) Tj 0.634925 0 Td 36.201843 Tz (F. ) Tj 1.019221 0 Td 46.296587 Tz (bubigeum ) Tj 2.372613 0 Td 27.847571 Tz (, ) Tj 0.735176 0 Td 37.594221 Tz (F. ) Tj 1.019221 0 Td 48.73325 Tz (culmorum ) Tj 2.506281 0 Td 25.062814 Tz (, ) Tj 0.68505 0 Td 38.9866 Tz (F. ) Tj 67.142857 0 0 67.142857 0 1080.203187 Tm 4.810638 0 Td 31.44208 Tz (ily ) Tj 0.580851 0 Td 9.929078 Tz (. ) Tj 0.312766 0 Td 55.437352 Tz (SEQ ) Tj 1.221277 0 Td 45.921986 Tz (ID ) Tj 0.744681 0 Td 65.780142 Tz (NO ) Tj 0.848936 0 Td 9.929078 Tz (: ) Tj 0.148936 0 Td 37.234043 Tz (6 ) Tj 0.446809 0 Td 27.304965 Tz (is ) Tj 0.53617 0 Td 37.234043 Tz (the ) Tj 0.878723 0 Td 41.646966 Tz (conserved ) Tj 2.42766 0 Td 37.588652 Tz (nucleic ) Tj 1.802128 0 Td 38.475177 Tz (acid ) Tj 1.117021 0 Td 45.921986 Tz (domain ) Tj 1.846809 0 Td 42.198582 Tz (of ) Tj 0.789362 0 Td 33.510638 Tz (45 ) Tj 0.774468 0 Td 44.003868 Tz (graminearum ) Tj 3.008511 0 Td 22.340426 Tz (, ) Tj 0.461702 0 Td 32.269504 Tz (F. ) Tj 0.729787 0 Td 38.588008 Tz (langsethiae ) Tj 2.502128 0 Td 24.822695 Tz (, ) Tj 0.461702 0 Td 32.269504 Tz (F. ) Tj 0.744681 0 Td 42.198582 Tz (oxysporum ) Tj 2.412766 0 Td 17.375887 Tz (, ) Tj 0.431915 0 Td 32.269504 Tz (F. ) Tj 0.655319 0 Td 47.163121 Tz (poae ) Tj 1.146809 0 Td 12.411348 Tz (, ) Tj 0.417021 0 Td 32.269504 Tz (F. ) Tj 60 0 0 60 0 1039.455548 Tm 5.366667 0 Td 41.666667 Tz (the ) Tj 1.116667 0 Td 55.555556 Tz (ETX ) Tj 1.283333 0 Td 19.444444 Tz (/ ) Tj 0.016667 0 Td 72.222222 Tz (MTX2 ) Tj 2.133333 0 Td 43.181818 Tz (superfamily ) Tj 2.883333 0 Td 27.777778 Tz (. ) Tj 0.533333 0 Td 62.962963 Tz (SEQ ) Tj 1.5 0 Td 51.388889 Tz (ID ) Tj 0.966667 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.15 0 Td 44.444444 Tz (7 ) Tj 0.633333 0 Td 31.944444 Tz (is ) Tj 0.733333 0 Td 41.666667 Tz (the ) Tj 1.116667 0 Td 31.666667 Tz (first ) Tj 2.2 0 Td 42.534722 Tz (sporotrichioides ) Tj 4.033333 0 Td 25 Tz (, ) Tj 0.533333 0 Td 36.111111 Tz (F. ) Tj 0.85 0 Td 39.444444 Tz (tricinctum ) Tj 2.483333 0 Td 25 Tz (, ) Tj 0.566667 0 Td 36.111111 Tz (F. ) Tj 0.85 0 Td 38.148148 Tz (verticillioides ) Tj 3.383333 0 Td 25 Tz (, ) Tj 0.566667 0 Td 49.074074 Tz (and ) Tj 1.233333 0 Td 36.111111 Tz (F. ) Tj 60.909091 0 0 60.909091 0 1000.24108 Tm 5.302985 0 Td 45.909342 Tz (conserved ) Tj 2.626866 0 Td 49.800995 Tz (amino ) Tj 1.658209 0 Td 42.412935 Tz (acid ) Tj 1.165672 0 Td 50.621891 Tz (domain ) Tj 1.970149 0 Td 45.149254 Tz (of ) Tj 0.623881 0 Td 41.044776 Tz (the ) Tj 0.853731 0 Td 44.328358 Tz (Agglutinin ) Tj 2.823881 0 Td 43.283582 Tz (superfamily ) Tj 2.807463 0 Td 27.363184 Tz (. ) Tj 1.461194 0 Td 42.868988 Tz (virguliforme ) Tj 2.922388 0 Td 27.363184 Tz (. ) Tj 59.183673 0 0 59.183673 0 956.703325 Tm 5.474483 0 Td 63.831418 Tz (SEQ ) Tj 1.385517 0 Td 53.505747 Tz (ID ) Tj 0.861724 0 Td 74.626437 Tz (NO ) Tj 0.963103 0 Td 11.264368 Tz (: ) Tj 0.152069 0 Td 42.241379 Tz (8 ) Tj 0.506897 0 Td 32.385057 Tz (is ) Tj 0.608276 0 Td 43.180077 Tz (the ) Tj 1.013793 0 Td 48.342912 Tz (second ) Tj 1.96 0 Td 47.247765 Tz (conserved ) Tj 2.771034 0 Td 50.689655 Tz (amino ) Tj 1.774138 0 Td 43.649425 Tz (acid ) Tj 1.267241 0 Td 52.56705 Tz (domain ) Tj 3.801724 0 Td 43.649425 Tz (In ) Tj 0.709655 0 Td 40.632184 Tz (certain ) Tj 1.892414 0 Td 42.867178 Tz (preferred ) Tj 2.517586 0 Td 51.201672 Tz (embodiments ) Tj 3.37931 0 Td 25.344828 Tz (, ) Tj 0.354828 0 Td 42.241379 Tz (a ) Tj 0.456207 0 Td 40.705329 Tz (genetically ) Tj 2.821724 0 Td 28.16092 Tz (- ) Tj 0.084483 0 Td 48.225575 Tz (modified ) Tj 62.012987 0 0 62.012987 0 915.336399 Tm 5.208586 0 Td 45.689354 Tz (of ) Tj 0.74178 0 Td 40.314136 Tz (the ) Tj 0.967539 0 Td 43.808028 Tz (Agglutinin ) Tj 2.902618 0 Td 43.001745 Tz (superfamily ) Tj 2.773613 0 Td 26.876091 Tz (. ) Tj 0.48377 0 Td 60.919139 Tz (SEQ ) Tj 1.386806 0 Td 49.720768 Tz (ID ) Tj 0.886911 0 Td 71.22164 Tz (NO ) Tj 0.919162 0 Td 10.750436 Tz (: ) Tj 0.145131 0 Td 40.314136 Tz (9 ) Tj 0.548272 0 Td 29.5637 Tz (is ) Tj 0.645026 0 Td 40.314136 Tz (the ) Tj 1.11267 0 Td 39.642234 Tz (con- ) Tj 2.176963 0 Td 39.776614 Tz (plant ) Tj 1.419058 0 Td 34.267016 Tz (cell ) Tj 1.064293 0 Td 44.34555 Tz (of ) Tj 0.677277 0 Td 40.314136 Tz (the ) Tj 0.951414 0 Td 41.807252 Tz (invention ) Tj 2.467225 0 Td 44.494861 Tz (comprises ) Tj 2.644607 0 Td 45.689354 Tz (an ) Tj 0.757906 0 Td 47.18247 Tz (exogenous ) Tj 2.757487 0 Td 41.082024 Tz (nucleic ) Tj 67.142857 0 0 67.142857 0 870.885604 Tm 4.825532 0 Td 39.716312 Tz (served ) Tj 1.623404 0 Td 45.177305 Tz (amino ) Tj 1.578723 0 Td 37.85461 Tz (acid ) Tj 1.102128 0 Td 46.335697 Tz (domain ) Tj 1.846809 0 Td 45.921986 Tz (of ) Tj 0.640426 0 Td 37.234043 Tz (the ) Tj 0.86383 0 Td 58.747045 Tz (ETX ) Tj 1.07234 0 Td 24.822695 Tz (/ ) Tj 0.178723 0 Td 61.43617 Tz (MTX2 ) Tj 1.712766 0 Td 39.941973 Tz (superfamily ) Tj 2.591489 0 Td 24.822695 Tz (. ) Tj 0.491489 0 Td 33.510638 Tz (50 ) Tj 0.789362 0 Td 38.475177 Tz (acid ) Tj 1.221277 0 Td 34.751773 Tz (that ) Tj 1.161702 0 Td 41.843972 Tz (encodes ) Tj 2.1 0 Td 37.234043 Tz (a ) Tj 0.551064 0 Td 37.588652 Tz (protein ) Tj 1.906383 0 Td 41.205674 Tz (comprising ) Tj 2.8 0 Td 37.234043 Tz (the ) Tj 0.997872 0 Td 45.177305 Tz (amino ) Tj 1.712766 0 Td 37.85461 Tz (acid ) Tj 58.285714 0 0 58.285714 0 830.771102 Tm 5.558824 0 Td 64.814815 Tz (SEQ ) Tj 1.47549 0 Td 52.900327 Tz (ID ) Tj 0.926471 0 Td 69.58061 Tz (NOS ) Tj 1.338235 0 Td 11.437908 Tz (: ) Tj 0.188725 0 Td 46.323529 Tz (10-13 ) Tj 1.715686 0 Td 41.938998 Tz (are ) Tj 1.046569 0 Td 76.252723 Tz (DNA ) Tj 1.612745 0 Td 46.160131 Tz (primers ) Tj 2.230392 0 Td 49.32598 Tz (used ) Tj 1.47549 0 Td 40.985839 Tz (for ) Tj 0.995098 0 Td 39.31781 Tz (real ) Tj 1.235294 0 Td 47.181373 Tz (time ) Tj 2.470588 0 Td 47.896242 Tz (sequence ) Tj 2.625 0 Td 48.611111 Tz (of ) Tj 0.840686 0 Td 64.814815 Tz (SEQ ) Tj 1.47549 0 Td 54.330065 Tz (ID ) Tj 0.960784 0 Td 75.776144 Tz (NO ) Tj 0.977941 0 Td 11.437908 Tz (: ) Tj 0.137255 0 Td 42.892157 Tz (3 ) Tj 0.343137 0 Td 14.297386 Tz (, ) Tj 0.428922 0 Td 45.751634 Tz (7 ) Tj 0.343137 0 Td 14.297386 Tz (, ) Tj 0.446078 0 Td 42.892157 Tz (8 ) Tj 0.32598 0 Td 14.297386 Tz (, ) Tj 0.428922 0 Td 44.321895 Tz (or ) Tj 0.840686 0 Td 42.892157 Tz (9 ) Tj 0.32598 0 Td 14.297386 Tz (, ) Tj 0.428922 0 Td 44.321895 Tz (or ) Tj 0.823529 0 Td 48.611111 Tz (an ) Tj 0.892157 0 Td 49.88199 Tz (exogenous ) Tj 58.714286 0 0 58.714286 0 791.145408 Tm 5.484185 0 Td 41.396323 Tz (quantitative ) Tj 3.150852 0 Td 66.234117 Tz (PCR ) Tj 1.345499 0 Td 41.159773 Tz (as ) Tj 0.681265 0 Td 44.786879 Tz (described ) Tj 2.571776 0 Td 41.159773 Tz (in ) Tj 0.63017 0 Td 42.579075 Tz (the ) Tj 0.93674 0 Td 69.190998 Tz (EXAMPLES ) Tj 3.525547 0 Td 42.17356 Tz (section ) Tj 1.924574 0 Td 48.256285 Tz (of ) Tj 1.822384 0 Td 42.98459 Tz (nucleic ) Tj 2.145985 0 Td 43.998378 Tz (acid ) Tj 1.345499 0 Td 39.030819 Tz (that ) Tj 1.260341 0 Td 46.994683 Tz (comprises ) Tj 2.895377 0 Td 28.38605 Tz (\( ) Tj 0.187348 0 Td 42.579075 Tz (a ) Tj 0.289538 0 Td 28.38605 Tz (\) ) Tj 0.510949 0 Td 42.579075 Tz (a ) Tj 0.562044 0 Td 43.998378 Tz (nucleotide ) Tj 2.980535 0 Td 47.546634 Tz (sequence ) Tj 2.605839 0 Td 48.256285 Tz (of ) Tj 65.714286 0 0 65.714286 0 743.023136 Tm 4.9 0 Td 33.605072 Tz (this ) Tj 0.973913 0 Td 38.433668 Tz (specification ) Tj 3.043478 0 Td 10.144928 Tz (. ) Tj 0.395652 0 Td 57.487923 Tz (SEQ ) Tj 1.247826 0 Td 54.528986 Tz (ID ) Tj 0.836957 0 Td 69.323671 Tz (NOS ) Tj 1.293478 0 Td 30.434783 Tz (: ) Tj 0.182609 0 Td 40.072464 Tz (14-15 ) Tj 1.536957 0 Td 37.198068 Tz (are ) Tj 0.958696 0 Td 67.63285 Tz (DNA ) Tj 1.46087 0 Td 42.028986 Tz (primers ) Tj 58.843537 0 0 58.843537 0 749.336406 Tm 22.058497 0 Td 64.200385 Tz (SEQ ) Tj 1.427514 0 Td 53.815029 Tz (ID ) Tj 0.900694 0 Td 75.057803 Tz (NO ) Tj 0.968671 0 Td 11.32948 Tz (: ) Tj 0.203931 0 Td 28.323699 Tz (1 ) Tj 0.288902 0 Td 14.16185 Tz (, ) Tj 0.390867 0 Td 45.317919 Tz (2 ) Tj 0.32289 0 Td 14.16185 Tz (, ) Tj 0.390867 0 Td 45.317919 Tz (4 ) Tj 0.339884 0 Td 14.16185 Tz (, ) Tj 0.407861 0 Td 39.653179 Tz (5 ) Tj 0.543815 0 Td 43.901734 Tz (or ) Tj 0.798728 0 Td 42.485549 Tz (6 ) Tj 0.339884 0 Td 14.16185 Tz (; ) Tj 0.390867 0 Td 43.901734 Tz (or ) Tj 0.798728 0 Td 28.323699 Tz (\( ) Tj 0.237919 0 Td 28.323699 Tz (b ) Tj 0.271908 0 Td 28.323699 Tz (\) ) Tj 0.458844 0 Td 42.485549 Tz (a ) Tj 0.509827 0 Td 44.184971 Tz (nucleotide ) Tj 2.94 0 Td 47.442197 Tz (sequence ) Tj 61.836735 0 0 61.836735 0 706.403579 Tm 5.207261 0 Td 46.493399 Tz (used ) Tj 1.309901 0 Td 38.632197 Tz (for ) Tj 0.873267 0 Td 38.118812 Tz (Tilling ) Tj 1.811221 0 Td 39.081408 Tz (as ) Tj 0.69538 0 Td 42.525364 Tz (described ) Tj 2.490429 0 Td 39.081408 Tz (in ) Tj 0.646865 0 Td 40.429043 Tz (the ) Tj 0.937954 0 Td 65.697195 Tz (EXAMPLES ) Tj 3.39604 0 Td 40.044004 Tz (section ) Tj 1.875908 0 Td 45.819582 Tz (of ) Tj 1.714191 0 Td 45.37037 Tz (having ) Tj 1.940594 0 Td 35.038504 Tz (at ) Tj 0.727723 0 Td 36.116612 Tz (least ) Tj 1.390759 0 Td 44.20242 Tz (about ) Tj 1.633333 0 Td 48.514851 Tz (70 ) Tj 0.59835 0 Td 78.162816 Tz (% ) Tj 0.808581 0 Td 45.482673 Tz (sequence ) Tj 2.490429 0 Td 37.733773 Tz (identity ) Tj 2.118482 0 Td 36.386139 Tz (to ) Tj 0.776238 0 Td 61.092776 Tz (SEQ ) Tj 1.423102 0 Td 49.862486 Tz (ID ) Tj 68.571429 0 0 68.571429 0 663.541192 Tm 4.695833 0 Td 32.204861 Tz (this ) Tj 1.079167 0 Td 33.840812 Tz (specification ) Tj 2.654167 0 Td 29.166667 Tz (. ) Tj 0.495833 0 Td 55.092593 Tz (SEQ ) Tj 1.26875 0 Td 46.180556 Tz (ID ) Tj 0.83125 0 Td 59.143519 Tz (NOS ) Tj 1.122917 0 Td 9.722222 Tz (: ) Tj 0.175 0 Td 37.916667 Tz (16-21 ) Tj 1.4875 0 Td 35.648148 Tz (are ) Tj 0.91875 0 Td 64.814815 Tz (DNA ) Tj 1.4 0 Td 39.236111 Tz (primers ) Tj 2.0125 0 Td 31.597222 Tz (55 ) Tj 0.83125 0 Td 53.472222 Tz (NO ) Tj 0.74375 0 Td 34.027778 Tz (: ) Tj 0.204167 0 Td 34.027778 Tz (1 ) Tj 0.204167 0 Td 34.027778 Tz (, ) Tj 0.35 0 Td 34.027778 Tz (2 ) Tj 0.291667 0 Td 34.027778 Tz (, ) Tj 0.277083 0 Td 38.888889 Tz (4 ) Tj 0.291667 0 Td 12.152778 Tz (, ) Tj 0.320833 0 Td 34.027778 Tz (5 ) Tj 0.452083 0 Td 37.673611 Tz (or ) Tj 0.65625 0 Td 36.458333 Tz (6 ) Tj 0.291667 0 Td 19.444444 Tz (; ) Tj 0.30625 0 Td 37.673611 Tz (or ) Tj 0.670833 0 Td 24.305556 Tz (\( ) Tj 0.160417 0 Td 34.027778 Tz (c ) Tj 0.247917 0 Td 24.305556 Tz (\) ) Tj 0.364583 0 Td 36.458333 Tz (a ) Tj 0.335417 0 Td 39.409722 Tz (polynucleotide ) Tj 3.514583 0 Td 34.027778 Tz (that ) Tj 1.035417 0 Td 34.690657 Tz (selectively ) Tj 55.178571 0 0 55.178571 0 628.050837 Tm 5.835599 0 Td 52.10356 Tz (used ) Tj 1.413592 0 Td 43.293779 Tz (for ) Tj 0.960518 0 Td 45.307443 Tz (association ) Tj 3.171521 0 Td 43.581446 Tz (studies ) Tj 2.029773 0 Td 43.797195 Tz (as ) Tj 0.724919 0 Td 47.656718 Tz (described ) Tj 2.754693 0 Td 42.286947 Tz (in ) Tj 0.652427 0 Td 46.314275 Tz (the ) Tj 1.014887 0 Td 73.247033 Tz (EXAMPLES ) Tj 4.92945 0 Td 46.515642 Tz (hybridizes ) Tj 3.117152 0 Td 42.286947 Tz (to ) Tj 0.797411 0 Td 48.32794 Tz (a ) Tj 0.579935 0 Td 47.89644 Tz (polynucleotide ) Tj 4.349515 0 Td 51.348436 Tz (sequence ) Tj 2.754693 0 Td 49.722015 Tz (corresponding ) Tj 4.168285 0 Td 39.266451 Tz (to ) Tj 60.492611 0 0 60.492611 0 580.356552 Tm 5.356026 0 Td 40.933768 Tz (section ) Tj 1.901059 0 Td 45.460098 Tz (of ) Tj 0.644707 0 Td 36.505836 Tz (this ) Tj 1.091042 0 Td 38.784139 Tz (specification ) Tj 3.041694 0 Td 27.551574 Tz (. ) Tj 0.396743 0 Td 62.450235 Tz (SEQ ) Tj 1.305945 0 Td 52.347991 Tz (ID ) Tj 0.793485 0 Td 67.042164 Tz (NOS ) Tj 1.289414 0 Td 11.02063 Tz (: ) Tj 0.132248 0 Td 46.837676 Tz (22-24 ) Tj 1.603502 0 Td 40.408976 Tz (are ) Tj 0.892671 0 Td 47.756062 Tz (mutant ) Tj 3.008632 0 Td 62.450235 Tz (SEQ ) Tj 1.438192 0 Td 50.970413 Tz (ID ) Tj 0.925733 0 Td 73.011672 Tz (NO ) Tj 0.942264 0 Td 11.02063 Tz (: ) Tj 0.18184 0 Td 27.551574 Tz (1 ) Tj 0.281026 0 Td 13.775787 Tz (, ) Tj 0.413274 0 Td 44.082519 Tz (2 ) Tj 0.330619 0 Td 13.775787 Tz (, ) Tj 0.413274 0 Td 44.082519 Tz (4 ) Tj 0.330619 0 Td 13.775787 Tz (, ) Tj 0.446336 0 Td 38.572204 Tz (5 ) Tj 0.578583 0 Td 41.327362 Tz (or ) Tj 0.810016 0 Td 33.061889 Tz (6. ) Tj 0.727362 0 Td 42.70494 Tz (In ) Tj 0.826547 0 Td 52.347991 Tz (some ) Tj 1.57044 0 Td 49.843303 Tz (embodiments ) Tj 3.636808 0 Td 39.949783 Tz (said ) Tj 60 0 0 60 0 540.552286 Tm 5.383333 0 Td 49.074074 Tz (and ) Tj 1.033333 0 Td 66.666667 Tz (R ) Tj 0.433333 0 Td 25 Tz (- ) Tj 0.166667 0 Td 57.407407 Tz (NIL ) Tj 1.166667 0 Td 47.916667 Tz (gene ) Tj 1.333333 0 Td 45.679012 Tz (sequences ) Tj 2.65 0 Td 53.333333 Tz (shown ) Tj 1.75 0 Td 43.253968 Tz (aligned ) Tj 1.966667 0 Td 38.888889 Tz (in ) Tj 0.616667 0 Td 54.62963 Tz (FIG ) Tj 1.033333 0 Td 11.111111 Tz (. ) Tj 0.25 0 Td 34.722222 Tz (3. ) Tj 0.616667 0 Td 62.962963 Tz (SEQ ) Tj 1.3 0 Td 51.388889 Tz (ID ) Tj 1.9 0 Td 42.063492 Tz (protein ) Tj 1.916667 0 Td 45.37037 Tz (has ) Tj 1 0 Td 59.722222 Tz (FHB1 ) Tj 1.683333 0 Td 38.541667 Tz (activity ) Tj 1.866667 0 Td 11.111111 Tz (. ) Tj 0.283333 0 Td 41.666667 Tz (In ) Tj 0.683333 0 Td 53.472222 Tz (some ) Tj 1.45 0 Td 50.505051 Tz (embodiments ) Tj 3.533333 0 Td 40.972222 Tz (said ) Tj 1.183333 0 Td 58.333333 Tz (exog ) Tj 55.974026 0 0 55.974026 0 501.50706 Tm 5.752668 0 Td 72.454241 Tz (NOS ) Tj 1.393503 0 Td 11.910286 Tz (: ) Tj 0.142923 0 Td 50.618716 Tz (25-27 ) Tj 1.858005 0 Td 43.671049 Tz (are ) Tj 1.107657 0 Td 51.114978 Tz (mutant ) Tj 2.161717 0 Td 52.603764 Tz (and ) Tj 1.268445 0 Td 71.461717 Tz (R ) Tj 0.464501 0 Td 26.798144 Tz (- ) Tj 0.178654 0 Td 61.536478 Tz (NIL ) Tj 1.411369 0 Td 53.596288 Tz (amino ) Tj 1.965197 0 Td 45.407966 Tz (acid ) Tj 1.429234 0 Td 48.96451 Tz (sequences ) Tj 4.037587 0 Td 50.618716 Tz (enous ) Tj 1.697216 0 Td 45.08894 Tz (nucleic ) Tj 2.108121 0 Td 46.152359 Tz (acid ) Tj 1.268445 0 Td 32.753287 Tz (is ) Tj 0.62529 0 Td 43.174787 Tz (stably ) Tj 1.732947 0 Td 44.365816 Tz (integrated ) Tj 2.822738 0 Td 41.686002 Tz (into ) Tj 1.214849 0 Td 44.663573 Tz (a ) Tj 0.446636 0 Td 57.169374 Tz (chromosome ) Tj 3.608817 0 Td 41.686002 Tz (in ) Tj 57.142857 0 0 57.142857 0 455.767296 Tm 5.67 0 Td 56 Tz (shown ) Tj 1.9075 0 Td 45.833333 Tz (aligned ) Tj 2.1525 0 Td 40.833333 Tz (in ) Tj 0.7175 0 Td 58.333333 Tz (FIG ) Tj 1.1025 0 Td 11.666667 Tz (. ) Tj 0.3325 0 Td 46.666667 Tz (4 ) Tj 0.3675 0 Td 11.666667 Tz (. ) Tj 55.714286 0 0 55.714286 0 459.756066 Tm 22.346154 0 Td 38.888889 Tz (60 ) Tj 0.915385 0 Td 44.871795 Tz (the ) Tj 1.076923 0 Td 48.290598 Tz (nucleus ) Tj 2.315385 0 Td 50.854701 Tz (of ) Tj 0.825641 0 Td 44.123932 Tz (said ) Tj 1.310256 0 Td 44.273504 Tz (plant ) Tj 1.615385 0 Td 38.141026 Tz (cell ) Tj 1.005128 0 Td 11.965812 Tz (. ) Tj 0.376923 0 Td 46.367521 Tz (In ) Tj 0.84359 0 Td 56.837607 Tz (some ) Tj 1.651282 0 Td 55.205905 Tz (embodiments ) Tj 3.571795 0 Td 26.923077 Tz (, ) Tj 0.484615 0 Td 43.376068 Tz (said ) Tj 58.571429 0 0 58.571429 0 419.180929 Tm 22.126829 0 Td 42.113821 Tz (plant ) Tj 1.434146 0 Td 36.99187 Tz (cell ) Tj 1.058537 0 Td 41.056911 Tz (further ) Tj 1.878049 0 Td 47.109304 Tz (comprises ) Tj 2.731707 0 Td 42.682927 Tz (a ) Tj 0.443902 0 Td 48.373984 Tz (second ) Tj 1.895122 0 Td 49.638663 Tz (exogenous ) Tj 2.85122 0 Td 43.089431 Tz (nucleic ) Tj 1.997561 0 Td 44.105691 Tz (acid ) Tj 45.714286 0 0 45.714286 0 382 Tm 10.040625 0 Td 95.520833 Tz (BACKGROUND ) Tj 6.0375 0 Td 82.03125 Tz (OF ) Tj 1.3125 0 Td 86.284722 Tz (THE ) Tj 1.859375 0 Td 83.043981 Tz (INVENTION ) Tj 58.095238 0 0 58.095238 0 376.414847 Tm 22.32541 0 Td 48.411885 Tz (encoding ) Tj 2.581967 0 Td 43.032787 Tz (a ) Tj 0.481967 0 Td 43.032787 Tz (native ) Tj 1.807377 0 Td 41.598361 Tz (resistance ) Tj 2.754098 0 Td 49.487705 Tz (gene ) Tj 1.239344 0 Td 11.47541 Tz (. ) Tj 60 0 0 60 0 339.511628 Tm 22.233333 0 Td 53.703704 Tz (The ) Tj 1.2 0 Td 42.063492 Tz (present ) Tj 2.033333 0 Td 43.209877 Tz (invention ) Tj 2.566667 0 Td 40.47619 Tz (further ) Tj 1.9 0 Td 44.444444 Tz (provides ) Tj 2.366667 0 Td 42.222222 Tz (transgenic ) Tj 2.8 0 Td 40.740741 Tz (plants ) Tj 47.142857 0 0 47.142857 0 298 Tm 12.833333 0 Td 53.737374 Tz (Field ) Tj 1.887879 0 Td 60.10101 Tz (of ) Tj 0.912121 0 Td 53.030303 Tz (the ) Tj 1.251515 0 Td 56.17284 Tz (Invention ) Tj 62.857143 0 0 62.857143 0 297.896552 Tm 20.618182 0 Td 45.959596 Tz (and ) Tj 0.986364 0 Td 42.424242 Tz (seeds ) Tj 1.4 0 Td 44.545455 Tz (comprising ) Tj 2.8 0 Td 42.424242 Tz (a ) Tj 0.381818 0 Td 37.121212 Tz (plurality ) Tj 2.131818 0 Td 47.727273 Tz (of ) Tj 0.636364 0 Td 38.181818 Tz (plant ) Tj 1.304545 0 Td 35 Tz (cells ) Tj 1.209091 0 Td 39.772727 Tz (as ) Tj 0.604545 0 Td 43.75 Tz (provided ) Tj 2.259091 0 Td 45.075758 Tz (by ) Tj 59.428571 0 0 59.428571 0 252.068878 Tm 20.949519 0 Td 35.05609 Tz (65 ) Tj 0.858173 0 Td 42.067308 Tz (the ) Tj 1.161058 0 Td 41.444088 Tz (invention ) Tj 2.372596 0 Td 19.63141 Tz (. ) Tj 0.471154 0 Td 43.469551 Tz (In ) Tj 0.875 0 Td 42.378917 Tz (preferred ) Tj 2.658654 0 Td 50.990676 Tz (embodiments ) Tj 3.331731 0 Td 25.240385 Tz (, ) Tj 0.538462 0 Td 42.067308 Tz (the ) Tj 1.110577 0 Td 42.908654 Tz (transgenic ) Tj 60.142857 0 0 60.142857 0 210.609756 Tm 6.002375 0 Td 51.728688 Tz (The ) Tj 1.097387 0 Td 42.755344 Tz (present ) Tj 1.978622 0 Td 43.415149 Tz (invention ) Tj 2.494062 0 Td 38.004751 Tz (relates ) Tj 1.779097 0 Td 38.796516 Tz (to ) Tj 0.648456 0 Td 49.485352 Tz (methods ) Tj 2.294537 0 Td 48.957509 Tz (and ) Tj 1.030879 0 Td 42.606888 Tz (reagents ) Tj 2.261283 0 Td 39.720243 Tz (for ) Tj 1.961995 0 Td 41.01346 Tz (plant ) Tj 1.429929 0 Td 42.953286 Tz (or ) Tj 0.698337 0 Td 45.031671 Tz (seed ) Tj 1.263658 0 Td 30.482977 Tz (is ) Tj 0.598575 0 Td 41.221298 Tz (selected ) Tj 2.16152 0 Td 49.881235 Tz (from ) Tj 1.36342 0 Td 41.567696 Tz (the ) Tj 0.947743 0 Td 46.555819 Tz (group ) Tj 1.612827 0 Td 41.567696 Tz (consisting ) Tj 2.693587 0 Td 47.110055 Tz (of ) Tj 0.68171 0 Td 49.326999 Tz (wheat ) Tj 63.333333 0 0 63.333333 0 169.595494 Tm 5.084211 0 Td 42.397661 Tz (providing ) Tj 2.589474 0 Td 43.859649 Tz (and ) Tj 0.931579 0 Td 18.421053 Tz (/ ) Tj 0.173684 0 Td 32.894737 Tz (or ) Tj 0.663158 0 Td 44.444444 Tz (enhancing ) Tj 2.684211 0 Td 38.684211 Tz (resistance ) Tj 2.605263 0 Td 35.526316 Tz (to ) Tj 0.710526 0 Td 47.368421 Tz (Fusarium ) Tj 2.589474 0 Td 51.973684 Tz (Head ) Tj 2.447368 0 Td 47.368421 Tz (and ) Tj 1.010526 0 Td 40.350877 Tz (barley ) Tj 1.452632 0 Td 26.315789 Tz (. ) Tj ET Q endstream endobj 171 0 obj << /Length 1 >> stream q endstream endobj 172 0 obj << /Length 59494 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 60.952381 0 0 60.952381 0 3027.187879 Tm 17.521875 0 Td 84.765625 Tz (US ) Tj 1.44375 0 Td 59.0625 Tz (11,072,799 ) Tj 3.904687 0 Td 71.09375 Tz (B2 ) Tj 48.571429 0 0 48.571429 0 2973 Tm 15.626471 0 Td 75.490196 Tz (3 ) Tj 48.571429 0 0 48.571429 0 2972 Tm 35.658824 0 Td 82.352941 Tz (4 ) Tj 57.669173 0 0 57.669173 0 2913.454023 Tm 6.259844 0 Td 53.947559 Tz (The ) Tj 1.161799 0 Td 44.589309 Tz (present ) Tj 2.080834 0 Td 44.956299 Tz (invention ) Tj 2.618383 0 Td 42.112125 Tz (further ) Tj 1.942112 0 Td 45.879509 Tz (provides ) Tj 2.42764 0 Td 43.350717 Tz (a ) Tj 0.450847 0 Td 42.524989 Tz (variety ) Tj 1.994133 0 Td 49.130813 Tz (of ) Tj 0.676271 0 Td 53.17688 Tz (meth- ) Tj 2.878488 0 Td 47.685789 Tz (cerned ) Tj 1.907432 0 Td 48.408301 Tz (with ) Tj 1.335202 0 Td 45.518253 Tz (uses ) Tj 1.335202 0 Td 49.130813 Tz (of ) Tj 0.728292 0 Td 52.02086 Tz (Fhbl ) Tj 1.525945 0 Td 51.195133 Tz (encoded ) Tj 2.340939 0 Td 44.176445 Tz (nucleic ) Tj 2.080834 0 Td 43.350717 Tz (acids ) Tj 1.525945 0 Td 42.387368 Tz (for ) Tj 0.953716 0 Td 42.937853 Tz (control ) Tj 62.071429 0 0 62.071429 0 2872.007368 Tm 5.203682 0 Td 44.751311 Tz (ods ) Tj 0.853855 0 Td 13.425393 Tz (, ) Tj 0.434983 0 Td 41.76789 Tz (including ) Tj 2.577675 0 Td 47.947833 Tz (methods ) Tj 2.352129 0 Td 38.486127 Tz (for ) Tj 1.01496 0 Td 40.813195 Tz (increasing ) Tj 2.754891 0 Td 40.872864 Tz (tolerance ) Tj 2.529344 0 Td 36.248562 Tz (to ) Tj 0.789413 0 Td 61.756809 Tz (FHB ) Tj 2.38435 0 Td 45.646337 Tz (of ) Tj 0.789413 0 Td 62.651835 Tz (FHB ) Tj 1.466053 0 Td 39.892597 Tz (disease ) Tj 1.72382 0 Td 24.165708 Tz (, ) Tj 0.451093 0 Td 41.469548 Tz (including ) Tj 2.223245 0 Td 26.850786 Tz (, ) Tj 0.483314 0 Td 42.066232 Tz (but ) Tj 1.063291 0 Td 42.066232 Tz (not ) Tj 1.063291 0 Td 40.659762 Tz (limited ) Tj 1.981588 0 Td 37.591101 Tz (to ) Tj 0.757192 0 Td 45.049653 Tz (producing ) Tj 62.10084 0 0 62.10084 0 2830.643081 Tm 5.201218 0 Td 39.362502 Tz (infection ) Tj 2.334912 0 Td 38.915201 Tz (in ) Tj 0.660217 0 Td 40.257104 Tz (a ) Tj 0.45088 0 Td 39.720343 Tz (plant ) Tj 1.400947 0 Td 36.902346 Tz (that ) Tj 1.111096 0 Td 42.174109 Tz (involve ) Tj 1.996752 0 Td 39.525157 Tz (genetically ) Tj 2.817997 0 Td 46.22112 Tz (modifying ) Tj 2.737483 0 Td 39.586152 Tz (said ) Tj 2.173884 0 Td 38.305245 Tz (genetically ) Tj 2.673072 0 Td 26.838069 Tz (- ) Tj 0.096617 0 Td 45.960194 Tz (modified ) Tj 2.463735 0 Td 38.915201 Tz (plants ) Tj 1.690798 0 Td 45.177417 Tz (having ) Tj 1.916238 0 Td 41.748108 Tz (increased ) Tj 2.512043 0 Td 39.451962 Tz (resistance ) Tj 2.624763 0 Td 36.231394 Tz (to ) Tj 60.571429 0 0 60.571429 0 2789.327485 Tm 5.316038 0 Td 41.273585 Tz (plant ) Tj 1.584906 0 Td 37.146226 Tz (to ) Tj 0.841981 0 Td 41.617531 Tz (increase ) Tj 2.377358 0 Td 43.75 Tz (expression ) Tj 2.988208 0 Td 46.77673 Tz (of ) Tj 0.858491 0 Td 64.203354 Tz (FHB ) Tj 1.535377 0 Td 40.448113 Tz (resistance ) Tj 2.806604 0 Td 38.178066 Tz (activity ) Tj 3.103774 0 Td 64.203354 Tz (FHB ) Tj 1.370283 0 Td 38.522013 Tz (as ) Tj 0.676887 0 Td 50.560142 Tz (compared ) Tj 2.575472 0 Td 38.522013 Tz (to ) Tj 0.660377 0 Td 41.273585 Tz (a ) Tj 0.445755 0 Td 40.880503 Tz (control ) Tj 1.898585 0 Td 42.374214 Tz (plant ) Tj 1.205189 0 Td 27.515723 Tz (. ) Tj 0.363208 0 Td 41.273585 Tz (In ) Tj 0.693396 0 Td 52.967767 Tz (some ) Tj 1.45283 0 Td 50.028588 Tz (embodiments ) Tj 3.285377 0 Td 24.764151 Tz (, ) Tj 65.714286 0 0 65.714286 0 2745.38173 Tm 4.9 0 Td 35.507246 Tz (relative ) Tj 1.841304 0 Td 35.507246 Tz (to ) Tj 0.593478 0 Td 38.043478 Tz (a ) Tj 0.395652 0 Td 37.318841 Tz (control ) Tj 1.734783 0 Td 40.072464 Tz (plant ) Tj 1.095652 0 Td 25.362319 Tz (. ) Tj 0.334783 0 Td 38.043478 Tz (In ) Tj 0.623913 0 Td 48.188406 Tz (some ) Tj 1.323913 0 Td 45.88274 Tz (embodiments ) Tj 3.180435 0 Td 38.888889 Tz (the ) Tj 0.836957 0 Td 47.7657 Tz (method ) Tj 2.176087 0 Td 27.898551 Tz (5 ) Tj 0.684783 0 Td 38.043478 Tz (the ) Tj 0.836957 0 Td 37.812912 Tz (genetically ) Tj 2.541304 0 Td 25.362319 Tz (- ) Tj 0.091304 0 Td 43.115942 Tz (modified ) Tj 2.191304 0 Td 37.198068 Tz (plants ) Tj 1.506522 0 Td 42.798913 Tz (comprise ) Tj 2.206522 0 Td 44.806763 Tz (one ) Tj 0.958696 0 Td 38.043478 Tz (or ) Tj 0.578261 0 Td 48.822464 Tz (more ) Tj 1.323913 0 Td 39.311594 Tz (copies ) Tj 62.857143 0 0 62.857143 0 2706.915088 Tm 5.138636 0 Td 43.897306 Tz (comprises ) Tj 2.815909 0 Td 42.424242 Tz (transforming ) Tj 3.515909 0 Td 39.109848 Tz (said ) Tj 1.336364 0 Td 39.772727 Tz (plant ) Tj 1.606818 0 Td 44.412879 Tz (with ) Tj 1.495455 0 Td 46.401515 Tz (an ) Tj 0.970455 0 Td 46.548822 Tz (exogenous ) Tj 3.754545 0 Td 45.075758 Tz (of ) Tj 0.684091 0 Td 46.254209 Tz (exogenous ) Tj 2.720455 0 Td 40.151515 Tz (nucleic ) Tj 1.909091 0 Td 41.098485 Tz (acid ) Tj 1.193182 0 Td 44.744318 Tz (encoding ) Tj 2.354545 0 Td 39.772727 Tz (a ) Tj 0.445455 0 Td 40.151515 Tz (protein ) Tj 1.893182 0 Td 39.772727 Tz (or ) Tj 0.668182 0 Td 44.486532 Tz (conserved ) Tj 60.068027 0 0 60.068027 0 2663.822663 Tm 5.360589 0 Td 42.412231 Tz (nucleic ) Tj 2.097622 0 Td 42.313137 Tz (acid ) Tj 1.315176 0 Td 46.821914 Tz (encoding ) Tj 2.547112 0 Td 41.619479 Tz (a ) Tj 0.532729 0 Td 42.412231 Tz (protein ) Tj 1.797961 0 Td 13.87316 Tz (, ) Tj 0.416195 0 Td 43.006795 Tz (or ) Tj 0.799094 0 Td 46.552158 Tz (conserved ) Tj 2.796829 0 Td 51.793129 Tz (domain ) Tj 2.147565 0 Td 43.006795 Tz (or ) Tj 1.781314 0 Td 51.330691 Tz (domain ) Tj 2.014383 0 Td 43.006795 Tz (or ) Tj 0.649264 0 Td 42.412231 Tz (residue ) Tj 1.947792 0 Td 46.706304 Tz (having ) Tj 1.847905 0 Td 43.700453 Tz (type ) Tj 1.231937 0 Td 44.394111 Tz (2 ) Tj 0.432843 0 Td 40.787089 Tz (resistance ) Tj 2.646999 0 Td 33.295583 Tz (\( ) Tj 0.183126 0 Td 40.509626 Tz (resistance ) Tj 2.597055 0 Td 37.457531 Tz (to ) Tj 0.615968 0 Td 42.544356 Tz (the ) Tj 64.829932 0 0 64.829932 0 2620.62987 Tm 4.966842 0 Td 39.664218 Tz (residue ) Tj 2.005247 0 Td 40.766002 Tz (thereof ) Tj 1.573347 0 Td 23.137461 Tz (, ) Tj 0.493599 0 Td 43.275621 Tz (having ) Tj 1.928122 0 Td 58.272123 Tz (FHB ) Tj 1.388248 0 Td 37.791186 Tz (resistance ) Tj 2.606821 0 Td 35.348898 Tz (activity ) Tj 1.712172 0 Td 12.854145 Tz (, ) Tj 0.416474 0 Td 40.766002 Tz (thereby ) Tj 2.930745 0 Td 41.133263 Tz (spread ) Tj 1.681322 0 Td 43.704092 Tz (of ) Tj 0.663274 0 Td 38.562434 Tz (the ) Tj 0.910073 0 Td 44.025446 Tz (pathogen ) Tj 2.329171 0 Td 34.963274 Tz (after ) Tj 1.249423 0 Td 31.217209 Tz (initial ) Tj 1.542497 0 Td 37.134196 Tz (infection ) Tj 2.051522 0 Td 25.70829 Tz (\) ) Tj 0.385624 0 Td 43.704092 Tz (of ) Tj 0.678699 0 Td 59.986009 Tz (FHB ) Tj 1.156873 0 Td 10.283316 Tz (. ) Tj 0.293075 0 Td 48.84575 Tz (The ) Tj 64.965986 0 0 64.965986 0 2580.385812 Tm 4.971832 0 Td 38.994764 Tz (increasing ) Tj 2.539791 0 Td 38.481675 Tz (the ) Tj 0.877382 0 Td 38.766725 Tz (tolerance ) Tj 2.308901 0 Td 42.329843 Tz (of ) Tj 0.677277 0 Td 37.198953 Tz (said ) Tj 1.077487 0 Td 37.968586 Tz (plant ) Tj 1.32377 0 Td 35.91623 Tz (to ) Tj 0.661885 0 Td 41.04712 Tz (spread ) Tj 1.662408 0 Td 43.612565 Tz (of ) Tj 0.661885 0 Td 44.895288 Tz (an ) Tj 0.785026 0 Td 52.591623 Tz (FHB- ) Tj 2.416649 0 Td 37.782009 Tz (genetically ) Tj 2.616754 0 Td 25.65445 Tz (- ) Tj 0.015393 0 Td 44.253927 Tz (modified ) Tj 2.231937 0 Td 37.626527 Tz (plants ) Tj 1.508482 0 Td 43.184991 Tz (having ) Tj 1.677801 0 Td 41.04712 Tz (type ) Tj 1.123665 0 Td 41.04712 Tz (2 ) Tj 0.400209 0 Td 37.712042 Tz (resistance ) Tj 2.401257 0 Td 43.612565 Tz (can ) Tj 0.92356 0 Td 36.557592 Tz (also ) Tj 57.142857 0 0 57.142857 0 2540.138539 Tm 5.6525 0 Td 47.083333 Tz (causing ) Tj 2.135 0 Td 48.489583 Tz (pathogen ) Tj 2.3625 0 Td 29.166667 Tz (. ) Tj 0.4025 0 Td 59.791667 Tz (Some ) Tj 1.6275 0 Td 52.765152 Tz (embodiments ) Tj 3.6575 0 Td 40.347222 Tz (result ) Tj 1.6275 0 Td 42.291667 Tz (in ) Tj 0.6825 0 Td 41.319444 Tz (stable ) Tj 1.68 0 Td 41.805556 Tz (incor- ) Tj 1.9775 0 Td 36.458333 Tz (10 ) Tj 0.8925 0 Td 49.583333 Tz (comprise ) Tj 2.7475 0 Td 44.583333 Tz (nucleic ) Tj 2.275 0 Td 45.208333 Tz (acid ) Tj 1.47 0 Td 49.21875 Tz (encoding ) Tj 2.765 0 Td 43.75 Tz (a ) Tj 0.6475 0 Td 44.166667 Tz (protein ) Tj 2.24 0 Td 45.208333 Tz (or ) Tj 0.91 0 Td 48.935185 Tz (conserved ) Tj 61.642857 0 0 61.642857 0 2496.635901 Tm 5.207416 0 Td 42.246041 Tz (poration ) Tj 2.206257 0 Td 45.963693 Tz (of ) Tj 0.648899 0 Td 40.556199 Tz (the ) Tj 0.924681 0 Td 47.465774 Tz (exogenous ) Tj 2.741599 0 Td 41.328698 Tz (nucleic ) Tj 1.946698 0 Td 39.880263 Tz (acid ) Tj 1.168019 0 Td 37.852453 Tz (into ) Tj 1.103129 0 Td 40.556199 Tz (the ) Tj 0.908459 0 Td 44.488922 Tz (transformed ) Tj 4.1854 0 Td 50.019312 Tz (domain ) Tj 2.02781 0 Td 41.908073 Tz (or ) Tj 0.713789 0 Td 41.328698 Tz (residue ) Tj 1.96292 0 Td 45.513068 Tz (having ) Tj 1.865585 0 Td 43.259946 Tz (type ) Tj 1.330243 0 Td 27.037466 Tz (1 ) Tj 0.454229 0 Td 39.745075 Tz (resistance ) Tj 2.595597 0 Td 37.852453 Tz (to ) Tj 0.713789 0 Td 63.087421 Tz (FHB ) Tj 1.411356 0 Td 35.148706 Tz (\( ) Tj 0.227115 0 Td 42.719197 Tz (resis ) Tj 55.793651 0 0 55.793651 0 2458.481215 Tm 5.753343 0 Td 44.807966 Tz (plant ) Tj 1.541394 0 Td 59.743954 Tz (genome ) Tj 2.097013 0 Td 20.910384 Tz (, ) Tj 0.376387 0 Td 52.773826 Tz (and ) Tj 1.147084 0 Td 41.820768 Tz (in ) Tj 0.716927 0 Td 56.756757 Tz (some ) Tj 1.57724 0 Td 54.041122 Tz (embodiments ) Tj 3.781792 0 Td 46.301565 Tz (multiple ) Tj 2.41963 0 Td 46.799431 Tz (copies ) Tj 1.899858 0 Td 50.782361 Tz (of ) Tj 1.917781 0 Td 46.600284 Tz (tance ) Tj 1.63101 0 Td 41.820768 Tz (to ) Tj 0.770697 0 Td 36.273115 Tz (initial ) Tj 1.792319 0 Td 43.812233 Tz (infection ) Tj 2.598862 0 Td 50.782361 Tz (of ) Tj 0.78862 0 Td 69.70128 Tz (FHB ) Tj 1.308393 0 Td 29.871977 Tz (\) ) Tj 0.250925 0 Td 11.948791 Tz (. ) Tj 61.339286 0 0 61.339286 0 2413.765625 Tm 5.233188 0 Td 40.756914 Tz (the ) Tj 0.994469 0 Td 47.700685 Tz (exogenous ) Tj 2.820378 0 Td 41.533236 Tz (nucleic ) Tj 2.021543 0 Td 41.436196 Tz (acid ) Tj 1.271616 0 Td 45.511887 Tz (sequence ) Tj 2.445415 0 Td 39.851205 Tz (are ) Tj 0.961863 0 Td 44.7091 Tz (transformed ) Tj 3.195342 0 Td 38.039787 Tz (into ) Tj 2.804076 0 Td 51.625425 Tz (The ) Tj 1.206405 0 Td 42.568333 Tz (invention ) Tj 2.575837 0 Td 39.20427 Tz (further ) Tj 1.891121 0 Td 43.134401 Tz (provides ) Tj 2.363901 0 Td 41.145075 Tz (nucleic ) Tj 2.037846 0 Td 40.213489 Tz (acids ) Tj 1.271616 0 Td 13.585638 Tz (, ) Tj 0.391266 0 Td 41.964526 Tz (including ) Tj 60.47619 0 0 60.47619 0 2375 Tm 5.307874 0 Td 43.175853 Tz (the ) Tj 0.959055 0 Td 45.748031 Tz (plant ) Tj 1.190551 0 Td 33.070866 Tz (. ) Tj 62.857143 0 0 62.857143 0 2373.373599 Tm 20.634091 0 Td 38.44697 Tz (isolated ) Tj 2.020455 0 Td 40.151515 Tz (nucleic ) Tj 1.925 0 Td 39.242424 Tz (acids ) Tj 1.4 0 Td 44.280303 Tz (comprising ) Tj 2.863636 0 Td 39.772727 Tz (a ) Tj 0.477273 0 Td 44.412879 Tz (sequence ) Tj 2.354545 0 Td 39.441288 Tz (selected ) Tj 2.084091 0 Td 47.727273 Tz (from ) Tj 71.428571 0 0 71.428571 0 2327.500618 Tm 4.928 0 Td 45.5 Tz (In ) Tj 0.686 0 Td 33.666667 Tz (certain ) Tj 1.54 0 Td 35.518519 Tz (preferred ) Tj 2.058 0 Td 43.484848 Tz (embodiments ) Tj 2.73 0 Td 30.333333 Tz (, ) Tj 0.35 0 Td 41.666667 Tz (methods ) Tj 1.918 0 Td 33.444444 Tz (for ) Tj 0.742 0 Td 35.466667 Tz (increasing ) Tj 2.492 0 Td 28 Tz (15 ) Tj 0.7 0 Td 35 Tz (the ) Tj 0.882 0 Td 39.2 Tz (group ) Tj 1.442 0 Td 35 Tz (consisting ) Tj 2.338 0 Td 38.5 Tz (of ) Tj 0.574 0 Td 32.666667 Tz (: ) Tj 0.28 0 Td 35 Tz (\( ) Tj 0.14 0 Td 35 Tz (a ) Tj 0.28 0 Td 35 Tz (\) ) Tj 0.35 0 Td 35 Tz (a ) Tj 0.434 0 Td 37 Tz (polynucleotide ) Tj 3.276 0 Td 42.291667 Tz (sequence ) Tj 2.212 0 Td 30.333333 Tz (at ) Tj 62.285714 0 0 62.285714 0 2289.594793 Tm 5.169725 0 Td 40.732246 Tz (tolerance ) Tj 2.408257 0 Td 36.123853 Tz (to ) Tj 0.674312 0 Td 62.43629 Tz (FHB ) Tj 1.380734 0 Td 39.245668 Tz (infection ) Tj 2.327982 0 Td 38.799694 Tz (in ) Tj 0.674312 0 Td 40.137615 Tz (a ) Tj 0.449541 0 Td 39.602446 Tz (plant ) Tj 1.412844 0 Td 42.431193 Tz (involve ) Tj 1.990826 0 Td 43.036442 Tz (transforming ) Tj 4.350917 0 Td 35.321101 Tz (least ) Tj 1.284404 0 Td 48.165138 Tz (70 ) Tj 0.770642 0 Td 53.51682 Tz (% ) Tj 0.577982 0 Td 37.164458 Tz (identical ) Tj 2.279817 0 Td 32.110092 Tz (to ) Tj 0.642202 0 Td 62.43629 Tz (SEQ ) Tj 1.348624 0 Td 50.840979 Tz (ID ) Tj 0.834862 0 Td 57.530581 Tz (NO ) Tj 0.899083 0 Td 21.406728 Tz (: ) Tj 0.272936 0 Td 21.406728 Tz (1 ) Tj 0.144495 0 Td 21.406728 Tz (; ) Tj 0.417431 0 Td 21.406728 Tz (\( ) Tj 0.192661 0 Td 42.813456 Tz (b ) Tj 0.321101 0 Td 21.406728 Tz (\) ) Tj 0.385321 0 Td 32.110092 Tz (a ) Tj 0.481651 0 Td 42.04893 Tz (polynucleotide ) Tj 58.238095 0 0 58.238095 0 2249.592617 Tm 5.529027 0 Td 42.927228 Tz (the ) Tj 1.047424 0 Td 42.354865 Tz (plant ) Tj 1.54538 0 Td 47.935405 Tz (with ) Tj 1.408013 0 Td 50.240756 Tz (exogenous ) Tj 3.004906 0 Td 43.336059 Tz (nucleic ) Tj 2.129191 0 Td 43.642682 Tz (acid ) Tj 1.322159 0 Td 48.650859 Tz (encoding ) Tj 2.627146 0 Td 42.927228 Tz (a ) Tj 0.515127 0 Td 43.74489 Tz (protein ) Tj 3.142273 0 Td 47.935405 Tz (sequence ) Tj 2.50695 0 Td 35.77269 Tz (at ) Tj 0.635323 0 Td 38.348324 Tz (least ) Tj 1.33933 0 Td 51.512674 Tz (70 ) Tj 0.635323 0 Td 82.992641 Tz (% ) Tj 0.704007 0 Td 40.383392 Tz (identical ) Tj 2.403925 0 Td 63.913873 Tz (SEQ ) Tj 1.3565 0 Td 54.374489 Tz (ID ) Tj 0.824203 0 Td 75.838103 Tz (NO ) Tj 0.978741 0 Td 11.447261 Tz (: ) Tj 0.154538 0 Td 45.789043 Tz (2 ) Tj 0.343418 0 Td 14.309076 Tz (, ) Tj 0.309076 0 Td 45.789043 Tz (4 ) Tj 0.326247 0 Td 14.309076 Tz (, ) Tj 0.326247 0 Td 40.065413 Tz (5 ) Tj 0.480785 0 Td 44.358136 Tz (or ) Tj 0.721177 0 Td 42.927228 Tz (6 ) Tj 0.326247 0 Td 14.309076 Tz (; ) Tj 0.343418 0 Td 28.618152 Tz (\( ) Tj 0.18888 0 Td 40.065413 Tz (c ) Tj 0.291905 0 Td 28.618152 Tz (\) ) Tj 62.261905 0 0 62.261905 0 2207.870071 Tm 5.187763 0 Td 44.703633 Tz (comprising ) Tj 2.858891 0 Td 40.152964 Tz (the ) Tj 0.899426 0 Td 48.718929 Tz (amino ) Tj 1.670363 0 Td 41.491396 Tz (acid ) Tj 1.188528 0 Td 44.837476 Tz (sequence ) Tj 2.344933 0 Td 44.16826 Tz (of ) Tj 0.67457 0 Td 60.67559 Tz (SEQ ) Tj 1.284895 0 Td 49.521989 Tz (ID ) Tj 0.770937 0 Td 70.936902 Tz (NO ) Tj 0.915488 0 Td 10.707457 Tz (: ) Tj 0.144551 0 Td 40.152964 Tz (3 ) Tj 0.321224 0 Td 13.384321 Tz (, ) Tj 0.289101 0 Td 42.829828 Tz (7 ) Tj 0.321224 0 Td 13.384321 Tz (, ) Tj 0.305163 0 Td 40.152964 Tz (8 ) Tj 0.305163 0 Td 13.384321 Tz (, ) Tj 1.333078 0 Td 40.152964 Tz (a ) Tj 0.465774 0 Td 42.447419 Tz (polynucleotide ) Tj 3.822562 0 Td 45.172084 Tz (sequence ) Tj 2.409178 0 Td 45.506692 Tz (encoding ) Tj 2.425239 0 Td 40.152964 Tz (a ) Tj 0.465774 0 Td 43.073179 Tz (polypeptide ) Tj 3.083748 0 Td 33.460803 Tz (at ) Tj 0.658509 0 Td 35.869981 Tz (least ) Tj 57.063492 0 0 57.063492 0 2167.26267 Tm 5.642837 0 Td 45.27121 Tz (or ) Tj 0.858693 0 Td 43.810848 Tz (9 ) Tj 0.332962 0 Td 14.603616 Tz (; ) Tj 0.438108 0 Td 45.27121 Tz (or ) Tj 0.823644 0 Td 43.810848 Tz (a ) Tj 0.560779 0 Td 44.645341 Tz (protein ) Tj 2.155494 0 Td 49.165508 Tz (having ) Tj 2.085396 0 Td 36.50904 Tz (at ) Tj 0.753547 0 Td 39.137691 Tz (least ) Tj 1.489569 0 Td 47.899861 Tz (about ) Tj 1.73491 0 Td 52.573018 Tz (70 ) Tj 0.665925 0 Td 84.700974 Tz (% ) Tj 0.823644 0 Td 53.157163 Tz (amino ) Tj 1.927677 0 Td 45.27121 Tz (acid ) Tj 2.435883 0 Td 52.573018 Tz (70 ) Tj 0.648401 0 Td 84.700974 Tz (% ) Tj 0.753547 0 Td 40.890125 Tz (identical ) Tj 2.418359 0 Td 40.890125 Tz (to ) Tj 0.753547 0 Td 65.229485 Tz (SEQ ) Tj 1.401947 0 Td 55.493741 Tz (ID ) Tj 0.876217 0 Td 77.399166 Tz (NO ) Tj 0.998887 0 Td 11.682893 Tz (: ) Tj 0.140195 0 Td 43.810848 Tz (3 ) Tj 0.350487 0 Td 14.603616 Tz (, ) Tj 0.332962 0 Td 46.731572 Tz (7 ) Tj 0.350487 0 Td 14.603616 Tz (, ) Tj 0.350487 0 Td 43.810848 Tz (8 ) Tj 0.332962 0 Td 14.603616 Tz (, ) Tj 0.332962 0 Td 45.27121 Tz (or ) Tj 0.771071 0 Td 43.810848 Tz (9 ) Tj 0.332962 0 Td 14.603616 Tz (; ) Tj 0.368011 0 Td 29.207232 Tz (\( ) Tj 0.192768 0 Td 52.573018 Tz (d ) Tj 0.332962 0 Td 29.207232 Tz (\) ) Tj 0.40306 0 Td 43.810848 Tz (a ) Tj 0.52573 0 Td 51.274919 Tz (polynucle ) Tj 60 0 0 60 0 2123.269358 Tm 5.383333 0 Td 39.236111 Tz (identity ) Tj 2.15 0 Td 46.527778 Tz (with ) Tj 1.416667 0 Td 62.962963 Tz (SEQ ) Tj 1.433333 0 Td 51.388889 Tz (ID ) Tj 0.9 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.133333 0 Td 41.666667 Tz (3 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 0.416667 0 Td 44.444444 Tz (7 ) Tj 0.316667 0 Td 13.888889 Tz (, ) Tj 0.433333 0 Td 41.666667 Tz (8 ) Tj 0.3 0 Td 13.888889 Tz (, ) Tj 0.416667 0 Td 41.666667 Tz (or ) Tj 0.8 0 Td 41.666667 Tz (9 ) Tj 0.55 0 Td 50 Tz (and ) Tj 1.15 0 Td 41.049383 Tz (retaining ) Tj 2.483333 0 Td 42.592593 Tz (the ) Tj 1.166667 0 Td 37.5 Tz (20 ) Tj 0.883333 0 Td 40.555556 Tz (otide ) Tj 1.383333 0 Td 46.875 Tz (sequence ) Tj 2.4 0 Td 36.111111 Tz (at ) Tj 0.566667 0 Td 37.777778 Tz (least ) Tj 1.283333 0 Td 48.611111 Tz (70 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.65 0 Td 39.197531 Tz (identical ) Tj 2.25 0 Td 37.5 Tz (to ) Tj 0.616667 0 Td 43.888889 Tz (bases ) Tj 1.5 0 Td 47.685185 Tz (69-377 ) Tj 1.883333 0 Td 45.833333 Tz (of ) Tj 0.65 0 Td 62.962963 Tz (SEQ ) Tj 63.809524 0 0 63.809524 0 2080.836066 Tm 5.06194 0 Td 38.91791 Tz (functional ) Tj 2.617164 0 Td 36.915423 Tz (characteristics ) Tj 3.604478 0 Td 44.402985 Tz (of ) Tj 0.720896 0 Td 39.179104 Tz (the ) Tj 0.95597 0 Td 39.552239 Tz (protein ) Tj 1.896269 0 Td 43.967662 Tz (having ) Tj 1.849254 0 Td 39.179104 Tz (the ) Tj 0.971642 0 Td 47.537313 Tz (amino ) Tj 2.648507 0 Td 48.320896 Tz (ID ) Tj 0.783582 0 Td 69.216418 Tz (NO ) Tj 0.893284 0 Td 10.447761 Tz (: ) Tj 0.18806 0 Td 26.119403 Tz (1 ) Tj 0.266418 0 Td 13.059701 Tz (; ) Tj 0.344776 0 Td 26.119403 Tz (\( ) Tj 0.172388 0 Td 39.179104 Tz (e ) Tj 0.266418 0 Td 26.119403 Tz (\) ) Tj 0.376119 0 Td 39.179104 Tz (a ) Tj 0.423134 0 Td 41.41791 Tz (polynucleotide ) Tj 3.714179 0 Td 43.75 Tz (sequence ) Tj 2.319403 0 Td 32.649254 Tz (at ) Tj 0.595522 0 Td 35.522388 Tz (least ) Tj 1.269403 0 Td 47.014925 Tz (70 ) Tj 0.579851 0 Td 75.746269 Tz (% ) Tj 0.783582 0 Td 45.05597 Tz (iden ) Tj 58.77551 0 0 58.77551 0 2041.226238 Tm 5.478472 0 Td 43.952546 Tz (acid ) Tj 1.310069 0 Td 47.497106 Tz (sequence ) Tj 2.535069 0 Td 48.206019 Tz (of ) Tj 0.782639 0 Td 63.329475 Tz (SEQ ) Tj 1.412153 0 Td 52.459491 Tz (ID ) Tj 0.884722 0 Td 75.144676 Tz (NO ) Tj 0.969792 0 Td 11.342593 Tz (: ) Tj 0.136111 0 Td 42.534722 Tz (3 ) Tj 0.357292 0 Td 11.342593 Tz (. ) Tj 0.340278 0 Td 52.932099 Tz (The ) Tj 1.207986 0 Td 42.534722 Tz (functional ) Tj 2.909375 0 Td 41.116898 Tz (character- ) Tj 3.726042 0 Td 35.729167 Tz (tical ) Tj 1.310069 0 Td 36.863426 Tz (to ) Tj 0.663542 0 Td 45.37037 Tz (bases ) Tj 1.599306 0 Td 50.096451 Tz (2330-2734 ) Tj 2.943403 0 Td 48.206019 Tz (of ) Tj 0.748611 0 Td 63.329475 Tz (SEQ ) Tj 1.429167 0 Td 48.206019 Tz (ID ) Tj 0.799653 0 Td 75.144676 Tz (NO ) Tj 0.969792 0 Td 11.342593 Tz (: ) Tj 0.187153 0 Td 28.356481 Tz (1 ) Tj 0.289236 0 Td 14.178241 Tz (, ) Tj 0.340278 0 Td 36.863426 Tz (\( ) Tj 0.30625 0 Td 25.520833 Tz (f ) Tj 0.119097 0 Td 25.520833 Tz (\) ) Tj 0.391319 0 Td 31.19213 Tz (a ) Tj 0.527431 0 Td 49.151235 Tz (polynucle ) Tj 60.642857 0 0 60.642857 0 2000.687831 Tm 5.342756 0 Td 33.896087 Tz (istics ) Tj 1.583039 0 Td 46.721633 Tz (of ) Tj 0.857479 0 Td 40.30886 Tz (the ) Tj 1.088339 0 Td 40.832352 Tz (protein ) Tj 2.077739 0 Td 41.774637 Tz (preferably ) Tj 2.869258 0 Td 45.805523 Tz (comprises ) Tj 2.836278 0 Td 40.30886 Tz (the ) Tj 1.088339 0 Td 36.906164 Tz (ability ) Tj 1.912839 0 Td 38.476639 Tz (to ) Tj 1.714959 0 Td 40.125638 Tz (otide ) Tj 1.418139 0 Td 46.03455 Tz (sequence ) Tj 2.407538 0 Td 34.354142 Tz (at ) Tj 0.61013 0 Td 36.82764 Tz (least ) Tj 1.286219 0 Td 49.469965 Tz (70 ) Tj 0.62662 0 Td 79.70161 Tz (% ) Tj 0.67609 0 Td 38.476639 Tz (identical ) Tj 2.275618 0 Td 37.102473 Tz (to ) Tj 0.64311 0 Td 43.423636 Tz (bases ) Tj 1.517079 0 Td 48.248484 Tz (2816-3103 ) Tj 2.836278 0 Td 46.721633 Tz (of ) Tj 61.428571 0 0 61.428571 0 1956.323797 Tm 5.25814 0 Td 42.958656 Tz (confer ) Tj 1.709302 0 Td 39.883721 Tz (resistance ) Tj 2.555814 0 Td 37.984496 Tz (to ) Tj 0.651163 0 Td 63.307494 Tz (FHB ) Tj 1.22093 0 Td 10.852713 Tz (. ) Tj 0.293023 0 Td 40.697674 Tz (In ) Tj 0.683721 0 Td 51.550388 Tz (some ) Tj 1.432558 0 Td 49.083862 Tz (embodiments ) Tj 3.434884 0 Td 40.697674 Tz (the ) Tj 0.895349 0 Td 41.472868 Tz (protein ) Tj 2.995349 0 Td 61.498708 Tz (SEQ ) Tj 1.351163 0 Td 51.550388 Tz (ID ) Tj 0.846512 0 Td 71.899225 Tz (NO ) Tj 0.927907 0 Td 10.852713 Tz (: ) Tj 0.17907 0 Td 27.131783 Tz (1 ) Tj 0.504651 0 Td 27.131783 Tz (\( ) Tj 0.17907 0 Td 46.124031 Tz (g ) Tj 0.309302 0 Td 27.131783 Tz (\) ) Tj 0.423256 0 Td 40.697674 Tz (a ) Tj 0.472093 0 Td 42.829457 Tz (polynucleotide ) Tj 3.874419 0 Td 45.445736 Tz (sequence ) Tj 2.425581 0 Td 35.271318 Tz (at ) Tj 0.667442 0 Td 36.356589 Tz (least ) Tj 1.334884 0 Td 47.48062 Tz (70 ) Tj 0.602326 0 Td 78.682171 Tz (% ) Tj 61.428571 0 0 61.428571 0 1915.86692 Tm 5.24186 0 Td 43.410853 Tz (has ) Tj 1.04186 0 Td 40.426357 Tz (antifungal ) Tj 2.669767 0 Td 37.645349 Tz (activity ) Tj 1.823256 0 Td 10.852713 Tz (. ) Tj 0.309302 0 Td 51.550388 Tz (The ) Tj 1.155814 0 Td 47.329888 Tz (exogenous ) Tj 2.8 0 Td 41.085271 Tz (nucleic ) Tj 1.969767 0 Td 42.054264 Tz (acid ) Tj 1.204651 0 Td 38.75969 Tz (prefer- ) Tj 2.034884 0 Td 35.271318 Tz (25 ) Tj 0.862791 0 Td 37.984496 Tz (identical ) Tj 2.246512 0 Td 36.627907 Tz (to ) Tj 0.634884 0 Td 42.868217 Tz (bases ) Tj 1.530233 0 Td 45.671835 Tz (19-498 ) Tj 1.839535 0 Td 46.124031 Tz (of ) Tj 0.683721 0 Td 61.498708 Tz (SEQ ) Tj 1.302326 0 Td 50.193798 Tz (ID ) Tj 0.781395 0 Td 71.899225 Tz (NO ) Tj 0.927907 0 Td 10.852713 Tz (: ) Tj 0.130233 0 Td 43.410853 Tz (2 ) Tj 0.34186 0 Td 13.565891 Tz (; ) Tj 0.309302 0 Td 32.55814 Tz (\( ) Tj 0.211628 0 Td 27.131783 Tz (h ) Tj 0.276744 0 Td 27.131783 Tz (\) ) Tj 0.374419 0 Td 40.697674 Tz (a ) Tj 0.406977 0 Td 48.535745 Tz (polynucle ) Tj 59.175824 0 0 59.175824 0 1875.311551 Tm 5.45831 0 Td 44.359331 Tz (ably ) Tj 1.267409 0 Td 46.628151 Tz (comprises ) Tj 2.771402 0 Td 28.164655 Tz (\( ) Tj 0.185887 0 Td 42.246982 Tz (a ) Tj 0.287279 0 Td 28.164655 Tz (\) ) Tj 0.388672 0 Td 42.246982 Tz (a ) Tj 0.456267 0 Td 43.655215 Tz (nucleotide ) Tj 2.838997 0 Td 47.527855 Tz (sequence ) Tj 2.484123 0 Td 47.879913 Tz (of ) Tj 0.726648 0 Td 63.839884 Tz (SEQ ) Tj 1.368802 0 Td 52.104612 Tz (ID ) Tj 0.828041 0 Td 74.636335 Tz (NO ) Tj 0.963231 0 Td 11.265862 Tz (: ) Tj 0.185887 0 Td 28.164655 Tz (1 ) Tj 0.287279 0 Td 14.082327 Tz (, ) Tj 1.4026 0 Td 41.120396 Tz (otide ) Tj 1.520891 0 Td 47.527855 Tz (sequence ) Tj 2.534819 0 Td 36.614051 Tz (at ) Tj 0.709749 0 Td 37.740638 Tz (least ) Tj 1.4026 0 Td 49.288146 Tz (70 ) Tj 0.625255 0 Td 81.677499 Tz (% ) Tj 0.760446 0 Td 39.743457 Tz (identical ) Tj 2.416527 0 Td 38.022284 Tz (to ) Tj 0.726648 0 Td 45.063448 Tz (bases ) Tj 1.639183 0 Td 47.879913 Tz (511-915 ) Tj 2.315135 0 Td 47.879913 Tz (of ) Tj 59.469388 0 0 59.469388 0 1833.345895 Tm 5.431366 0 Td 44.840997 Tz (2 ) Tj 0.336307 0 Td 14.012812 Tz (, ) Tj 0.269046 0 Td 44.840997 Tz (4 ) Tj 0.319492 0 Td 14.012812 Tz (, ) Tj 0.285861 0 Td 39.235873 Tz (5 ) Tj 0.4372 0 Td 42.038435 Tz (or ) Tj 0.6558 0 Td 42.038435 Tz (6 ) Tj 0.336307 0 Td 14.012812 Tz (; ) Tj 0.269046 0 Td 43.439716 Tz (or ) Tj 0.672615 0 Td 28.025623 Tz (\( ) Tj 0.252231 0 Td 28.025623 Tz (b ) Tj 0.252231 0 Td 28.025623 Tz (\) ) Tj 0.336307 0 Td 42.038435 Tz (a ) Tj 0.386754 0 Td 43.439716 Tz (nucleotide ) Tj 2.774537 0 Td 47.29324 Tz (sequence ) Tj 2.404598 0 Td 47.176466 Tz (having ) Tj 1.849691 0 Td 36.43331 Tz (at ) Tj 0.588538 0 Td 37.554335 Tz (least ) Tj 1.277968 0 Td 45.962022 Tz (about ) Tj 2.69046 0 Td 63.524746 Tz (SEQ ) Tj 1.395676 0 Td 51.847403 Tz (ID ) Tj 0.874399 0 Td 74.267902 Tz (NO ) Tj 0.958476 0 Td 11.210249 Tz (: ) Tj 0.134523 0 Td 44.840997 Tz (2 ) Tj 0.353123 0 Td 14.012812 Tz (; ) Tj 0.369938 0 Td 28.025623 Tz (\( ) Tj 0.201784 0 Td 22.420499 Tz (i ) Tj 0.168154 0 Td 28.025623 Tz (\) ) Tj 0.4372 0 Td 42.038435 Tz (a ) Tj 0.487646 0 Td 44.240448 Tz (polynucleotide ) Tj 3.985244 0 Td 47.29324 Tz (sequence ) Tj 2.522306 0 Td 35.032029 Tz (at ) Tj 0.672615 0 Td 37.554335 Tz (least ) Tj 1.378861 0 Td 49.044841 Tz (70 ) Tj 0.622169 0 Td 81.274308 Tz (% ) Tj 56.163265 0 0 56.163265 0 1793.335575 Tm 5.733285 0 Td 53.415698 Tz (70 ) Tj 0.676599 0 Td 86.058624 Tz (% ) Tj 0.78343 0 Td 50.077217 Tz (sequence ) Tj 2.65298 0 Td 41.545543 Tz (identity ) Tj 2.243459 0 Td 40.061773 Tz (to ) Tj 0.765625 0 Td 67.264212 Tz (SEQ ) Tj 1.460029 0 Td 56.383236 Tz (ID ) Tj 0.908067 0 Td 78.639777 Tz (NO ) Tj 1.014898 0 Td 11.870155 Tz (: ) Tj 0.213663 0 Td 29.675388 Tz (1 ) Tj 0.284884 0 Td 14.837694 Tz (, ) Tj 0.37391 0 Td 47.48062 Tz (2 ) Tj 0.356105 0 Td 14.837694 Tz (, ) Tj 0.37391 0 Td 47.48062 Tz (4 ) Tj 0.338299 0 Td 14.837694 Tz (, ) Tj 0.391715 0 Td 41.545543 Tz (5 ) Tj 0.534157 0 Td 45.996851 Tz (or ) Tj 0.801235 0 Td 44.513081 Tz (6 ) Tj 0.356105 0 Td 11.870155 Tz (. ) Tj 2.831032 0 Td 41.545543 Tz (identical ) Tj 2.546148 0 Td 40.061773 Tz (to ) Tj 0.78343 0 Td 46.887112 Tz (bases ) Tj 1.744913 0 Td 51.931928 Tz (997-1284 ) Tj 2.795422 0 Td 50.448159 Tz (of ) Tj 0.854651 0 Td 66.275032 Tz (SEQ ) Tj 1.49564 0 Td 56.383236 Tz (ID ) Tj 0.961483 0 Td 78.639777 Tz (NO ) Tj 1.014898 0 Td 11.870155 Tz (: ) Tj 0.142442 0 Td 47.48062 Tz (2 ) Tj 0.37391 0 Td 14.837694 Tz (; ) Tj 0.427326 0 Td 35.610465 Tz (\( ) Tj 0.231468 0 Td 29.675388 Tz (j ) Tj 0.160247 0 Td 29.675388 Tz (\) ) Tj 0.498547 0 Td 44.513081 Tz (a ) Tj 0.551962 0 Td 58.608891 Tz (poly ) Tj 60.756303 0 0 60.756303 0 1750.625405 Tm 5.94177 0 Td 51.206393 Tz (The ) Tj 1.119225 0 Td 41.931766 Tz (present ) Tj 1.975104 0 Td 42.671994 Tz (invention ) Tj 2.501798 0 Td 39.776395 Tz (also ) Tj 1.168603 0 Td 43.548294 Tz (provides ) Tj 2.287828 0 Td 49.377593 Tz (methods ) Tj 2.287828 0 Td 39.319195 Tz (for ) Tj 0.938174 0 Td 44.674965 Tz (produc- ) Tj 3.110788 0 Td 42.519594 Tz (nucleotide ) Tj 2.8639 0 Td 45.948594 Tz (sequence ) Tj 2.501798 0 Td 46.291494 Tz (encoding ) Tj 2.518257 0 Td 41.147994 Tz (a ) Tj 0.510235 0 Td 43.891194 Tz (polypeptide ) Tj 3.176625 0 Td 35.661595 Tz (at ) Tj 0.707746 0 Td 36.758875 Tz (least ) Tj 1.399032 0 Td 48.005994 Tz (70 ) Tj 0.60899 0 Td 79.552789 Tz (% ) Tj 64.285714 0 0 64.285714 0 1706.747682 Tm 5.024444 0 Td 39.753086 Tz (ing ) Tj 0.98 0 Td 38.888889 Tz (a ) Tj 0.513333 0 Td 38.417508 Tz (genetically ) Tj 2.582222 0 Td 25.925926 Tz (- ) Tj 0.077778 0 Td 44.722222 Tz (modified ) Tj 2.38 0 Td 38.37037 Tz (plant ) Tj 1.415556 0 Td 40.185185 Tz (or ) Tj 0.746667 0 Td 41.481481 Tz (seed ) Tj 1.244444 0 Td 43.641975 Tz (having ) Tj 1.835556 0 Td 40.617284 Tz (increased ) Tj 2.551111 0 Td 35 Tz (30 ) Tj 0.824444 0 Td 36.296296 Tz (identical ) Tj 2.224444 0 Td 36.296296 Tz (to ) Tj 0.7 0 Td 39.212963 Tz (residues ) Tj 2.162222 0 Td 44.074074 Tz (7-166 ) Tj 1.602222 0 Td 44.074074 Tz (of ) Tj 0.746667 0 Td 58.765432 Tz (SEQ ) Tj 1.322222 0 Td 49.259259 Tz (ID ) Tj 0.855556 0 Td 68.703704 Tz (NO ) Tj 0.886667 0 Td 10.37037 Tz (: ) Tj 0.124444 0 Td 38.888889 Tz (3 ) Tj 0.326667 0 Td 12.962963 Tz (; ) Tj 0.388889 0 Td 28.518519 Tz (\( ) Tj 0.264444 0 Td 25.925926 Tz (k ) Tj 0.202222 0 Td 25.925926 Tz (\) ) Tj 0.435556 0 Td 38.888889 Tz (a ) Tj 0.513333 0 Td 49.907407 Tz (poly ) Tj 59.172932 0 0 59.172932 0 1667.247082 Tm 5.441677 0 Td 42.874959 Tz (tolerance ) Tj 2.534943 0 Td 39.432444 Tz (to ) Tj 0.726684 0 Td 65.72074 Tz (FHB ) Tj 1.453367 0 Td 51.755083 Tz (compared ) Tj 2.703939 0 Td 38.024142 Tz (to ) Tj 0.726684 0 Td 42.249047 Tz (a ) Tj 0.490089 0 Td 41.846675 Tz (control ) Tj 1.994155 0 Td 42.249047 Tz (plant ) Tj 1.487166 0 Td 39.432444 Tz (that ) Tj 1.182973 0 Td 44.663278 Tz (involve ) Tj 3.160229 0 Td 43.657349 Tz (nucleotide ) Tj 2.940534 0 Td 47.178102 Tz (sequence ) Tj 2.568742 0 Td 47.530178 Tz (encoding ) Tj 2.585642 0 Td 42.249047 Tz (a ) Tj 0.523888 0 Td 45.06565 Tz (polypeptide ) Tj 3.261626 0 Td 36.615841 Tz (at ) Tj 0.726684 0 Td 37.742482 Tz (least ) Tj 1.436468 0 Td 49.290555 Tz (70 ) Tj 0.625286 0 Td 81.681491 Tz (% ) Tj 59.835165 0 0 59.835165 0 1623.433577 Tm 5.398163 0 Td 42.825987 Tz (crossing ) Tj 2.323049 0 Td 41.781451 Tz (a ) Tj 0.534803 0 Td 31.196817 Tz (first ) Tj 1.186593 0 Td 43.638404 Tz (parent ) Tj 1.804959 0 Td 41.781451 Tz (plant ) Tj 1.504132 0 Td 46.655953 Tz (with ) Tj 1.370432 0 Td 41.781451 Tz (a ) Tj 0.534803 0 Td 47.352311 Tz (second ) Tj 1.955372 0 Td 43.174166 Tz (parent ) Tj 1.804959 0 Td 41.224365 Tz (plant ) Tj 1.48742 0 Td 38.996021 Tz (to ) Tj 1.771534 0 Td 38.996021 Tz (identical ) Tj 2.506887 0 Td 37.603306 Tz (to ) Tj 0.852342 0 Td 42.12963 Tz (residues ) Tj 2.5236 0 Td 45.760637 Tz (171-305 ) Tj 2.356474 0 Td 47.352311 Tz (of ) Tj 0.902479 0 Td 63.136415 Tz (SEQ ) Tj 1.687971 0 Td 20.890725 Tz (ID ) Tj 0.852342 0 Td 73.813897 Tz (NO ) Tj 0.952617 0 Td 11.14172 Tz (: ) Tj 0.150413 0 Td 41.781451 Tz (3 ) Tj 0.334252 0 Td 13.92715 Tz (; ) Tj 0.534803 0 Td 33.425161 Tz (\( ) Tj 0.284114 0 Td 27.854301 Tz (1 ) Tj 0.217264 0 Td 27.854301 Tz (\) ) Tj 0.568228 0 Td 36.210591 Tz (a ) Tj 63.007519 0 0 63.007519 0 1584.623087 Tm 5.09463 0 Td 42.322991 Tz (thereby ) Tj 1.936277 0 Td 45.346062 Tz (produce ) Tj 2.079117 0 Td 45.346062 Tz (progeny ) Tj 1.920406 0 Td 18.516309 Tz (, ) Tj 0.28568 0 Td 45.723946 Tz (wherein ) Tj 2.094988 0 Td 33.064837 Tz (at ) Tj 0.587232 0 Td 35.445505 Tz (least ) Tj 1.237947 0 Td 46.731636 Tz (one ) Tj 1.015752 0 Td 44.968178 Tz (of ) Tj 0.634845 0 Td 39.677804 Tz (the ) Tj 0.904654 0 Td 30.155131 Tz (first ) Tj 1.079236 0 Td 41.000398 Tz (or ) Tj 1.69821 0 Td 41.945107 Tz (polynucleotide ) Tj 3.840811 0 Td 44.968178 Tz (sequence ) Tj 2.475895 0 Td 44.968178 Tz (encoding ) Tj 2.475895 0 Td 37.032617 Tz (a ) Tj 0.539618 0 Td 42.322991 Tz (polypeptide ) Tj 3.11074 0 Td 34.38743 Tz (at ) Tj 0.761814 0 Td 34.916468 Tz (least ) Tj 57.438424 0 0 57.438424 0 1541.831916 Tm 5.623413 0 Td 49.328188 Tz (second ) Tj 1.915094 0 Td 44.9757 Tz (parent ) Tj 1.775815 0 Td 42.557652 Tz (plants ) Tj 1.723585 0 Td 31.918239 Tz (is ) Tj 0.574528 0 Td 43.524871 Tz (a ) Tj 0.417839 0 Td 44.105203 Tz (transgenic ) Tj 2.820412 0 Td 42.94454 Tz (plant ) Tj 1.462436 0 Td 49.328188 Tz (of ) Tj 0.661578 0 Td 43.524871 Tz (the ) Tj 0.957547 0 Td 45.45931 Tz (invention ) Tj 2.454803 0 Td 23.213265 Tz (. ) Tj 0.313379 0 Td 44.9757 Tz (In ) Tj 1.880274 0 Td 52.229846 Tz (70 ) Tj 0.644168 0 Td 84.148085 Tz (% ) Tj 0.748628 0 Td 40.94562 Tz (identical ) Tj 2.437393 0 Td 40.623213 Tz (to ) Tj 0.713808 0 Td 43.887579 Tz (residues ) Tj 2.367753 0 Td 50.571755 Tz (351-428 ) Tj 2.367753 0 Td 49.328188 Tz (of ) Tj 0.766038 0 Td 65.770917 Tz (SEQ ) Tj 1.427616 0 Td 53.680675 Tz (ID ) Tj 0.870497 0 Td 76.893939 Tz (NO ) Tj 0.992367 0 Td 11.606632 Tz (: ) Tj 0.15669 0 Td 43.524871 Tz (3 ) Tj 0.348199 0 Td 14.50829 Tz (; ) Tj 0.383019 0 Td 29.016581 Tz (\( ) Tj 0.208919 0 Td 29.016581 Tz (m ) Tj 0.487479 0 Td 29.016581 Tz (\) ) Tj 0.435249 0 Td 43.524871 Tz (a ) Tj 62.857143 0 0 62.857143 0 1501.877771 Tm 5.154545 0 Td 50.378788 Tz (some ) Tj 1.4 0 Td 47.727273 Tz (embodiments ) Tj 3.165909 0 Td 23.863636 Tz (, ) Tj 0.334091 0 Td 40.656566 Tz (the ) Tj 0.890909 0 Td 48.611111 Tz (method ) Tj 1.972727 0 Td 37.878788 Tz (further ) Tj 1.75 0 Td 44.191919 Tz (comprises ) Tj 2.577273 0 Td 45.075758 Tz (pyramid- ) Tj 2.545455 0 Td 34.469697 Tz (35 ) Tj 0.827273 0 Td 42.045455 Tz (polynucleotide ) Tj 3.786364 0 Td 45.075758 Tz (sequence ) Tj 2.418182 0 Td 45.075758 Tz (encoding ) Tj 2.418182 0 Td 37.121212 Tz (a ) Tj 0.477273 0 Td 42.424242 Tz (polypeptide ) Tj 3.054545 0 Td 44.412879 Tz (fragment ) Tj 60.150376 0 0 60.150376 0 1459.216765 Tm 5.35325 0 Td 42.486111 Tz (ing ) Tj 1.09725 0 Td 40.869792 Tz (said ) Tj 1.280125 0 Td 48.335648 Tz (exogenous ) Tj 2.926 0 Td 41.958333 Tz (nucleic ) Tj 2.09475 0 Td 42.255208 Tz (acid ) Tj 1.313375 0 Td 45.71875 Tz (with ) Tj 1.3965 0 Td 41.5625 Tz (a ) Tj 0.548625 0 Td 42.024306 Tz (native ) Tj 1.812125 0 Td 40.73125 Tz (resistance ) Tj 3.724 0 Td 41.5625 Tz (consisting ) Tj 2.7265 0 Td 45.71875 Tz (of ) Tj 0.714875 0 Td 36.020833 Tz (at ) Tj 0.648375 0 Td 37.129167 Tz (least ) Tj 1.346625 0 Td 45.71875 Tz (25 ) Tj 0.814625 0 Td 44.8875 Tz (contiguous ) Tj 2.926 0 Td 50.429167 Tz (amino ) Tj 1.76225 0 Td 42.947917 Tz (acid ) Tj 1.213625 0 Td 41.908854 Tz (residues ) Tj 2.261 0 Td 47.104167 Tz (of ) Tj 42.857143 0 0 42.857143 0 1420.487179 Tm 7.49 0 Td 68.055556 Tz (gene ) Tj 1.656667 0 Td 31.111111 Tz (. ) Tj 60 0 0 60 0 1415.335559 Tm 21.633333 0 Td 62.962963 Tz (SEQ ) Tj 1.516667 0 Td 52.777778 Tz (ID ) Tj 1.016667 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.5 0 Td 41.666667 Tz (3 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 0.5 0 Td 44.444444 Tz (7 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 0.516667 0 Td 41.666667 Tz (8 ) Tj 0.316667 0 Td 13.888889 Tz (, ) Tj 0.5 0 Td 43.055556 Tz (or ) Tj 0.9 0 Td 41.666667 Tz (9 ) Tj 0.333333 0 Td 13.888889 Tz (; ) Tj 0.516667 0 Td 30.555556 Tz (\( ) Tj 0.266667 0 Td 27.777778 Tz (n ) Tj 0.233333 0 Td 27.777778 Tz (\) ) Tj 0.566667 0 Td 41.666667 Tz (a ) Tj 0.633333 0 Td 44.047619 Tz (polynucleotide ) Tj 4.066667 0 Td 38.888889 Tz (that ) Tj 63.809524 0 0 63.809524 0 1375.408069 Tm 5.657463 0 Td 48.756219 Tz (The ) Tj 1.206716 0 Td 40.630182 Tz (invention ) Tj 2.507463 0 Td 37.873134 Tz (also ) Tj 1.222388 0 Td 41.791045 Tz (provides ) Tj 2.319403 0 Td 47.014925 Tz (methods ) Tj 2.303731 0 Td 44.402985 Tz (of ) Tj 0.783582 0 Td 38.704206 Tz (identifying ) Tj 2.883582 0 Td 39.179104 Tz (a ) Tj 1.457463 0 Td 37.279512 Tz (selectively ) Tj 2.711194 0 Td 40.223881 Tz (hybridizes ) Tj 2.664179 0 Td 36.567164 Tz (to ) Tj 0.705224 0 Td 39.179104 Tz (a ) Tj 0.470149 0 Td 41.41791 Tz (polynucleotide ) Tj 3.745522 0 Td 44.076493 Tz (sequence ) Tj 2.460448 0 Td 42.313433 Tz (corre ) Tj 58.190476 0 0 58.190476 0 1334.368789 Tm 5.516367 0 Td 42.962357 Tz (plant ) Tj 1.581015 0 Td 47.831424 Tz (comprising ) Tj 3.179214 0 Td 37.234043 Tz (at ) Tj 0.756137 0 Td 38.379705 Tz (least ) Tj 1.46072 0 Td 49.64539 Tz (one ) Tj 1.202946 0 Td 37.711402 Tz (allele ) Tj 1.666939 0 Td 43.821604 Tz (associated ) Tj 2.92144 0 Td 46.542553 Tz (with ) Tj 1.443535 0 Td 65.875614 Tz (FHB ) Tj 2.577741 0 Td 47.974632 Tz (sponding ) Tj 2.526187 0 Td 38.666121 Tz (to ) Tj 0.738953 0 Td 63.966176 Tz (SEQ ) Tj 1.39198 0 Td 54.418985 Tz (ID ) Tj 0.859247 0 Td 70.649209 Tz (NOS ) Tj 1.340426 0 Td 11.456628 Tz (: ) Tj 0.395254 0 Td 28.641571 Tz (1 ) Tj 0.292144 0 Td 14.320786 Tz (, ) Tj 0.343699 0 Td 45.826514 Tz (2 ) Tj 0.343699 0 Td 14.320786 Tz (, ) Tj 0.343699 0 Td 45.826514 Tz (4 ) Tj 0.343699 0 Td 14.320786 Tz (, ) Tj 0.360884 0 Td 40.0982 Tz (5 ) Tj 0.498363 0 Td 44.394435 Tz (or ) Tj 0.756137 0 Td 42.962357 Tz (6 ) Tj 0.343699 0 Td 14.320786 Tz (; ) Tj 0.343699 0 Td 51.554828 Tz (and ) Tj 1.151391 0 Td 28.641571 Tz (\( ) Tj 0.189034 0 Td 45.826514 Tz (o ) Tj 0.326514 0 Td 28.641571 Tz (\) ) Tj 0.481178 0 Td 57.283142 Tz (comple ) Tj 62.857143 0 0 62.857143 0 1290.169742 Tm 5.122727 0 Td 38.977273 Tz (resistance ) Tj 2.593182 0 Td 36.789773 Tz (activity ) Tj 2.020455 0 Td 37.121212 Tz (in ) Tj 0.684091 0 Td 39.772727 Tz (a ) Tj 0.477273 0 Td 39.242424 Tz (plant ) Tj 1.415909 0 Td 37.121212 Tz (that ) Tj 1.145455 0 Td 44.781145 Tz (comprises ) Tj 2.354545 0 Td 26.515152 Tz (: ) Tj 0.461364 0 Td 26.515152 Tz (\( ) Tj 0.190909 0 Td 39.772727 Tz (a ) Tj 0.254545 0 Td 26.515152 Tz (\) ) Tj 0.445455 0 Td 41.540404 Tz (screening ) Tj 2.609091 0 Td 37.121212 Tz (40 ) Tj 0.843182 0 Td 46.666667 Tz (ments ) Tj 1.559091 0 Td 45.075758 Tz (of ) Tj 0.620455 0 Td 39.772727 Tz (a ) Tj 0.365909 0 Td 42.045455 Tz (polynucleotide ) Tj 3.690909 0 Td 39.441288 Tz (selected ) Tj 2.020455 0 Td 47.727273 Tz (from ) Tj 1.256818 0 Td 39.772727 Tz (the ) Tj 0.875 0 Td 44.545455 Tz (group ) Tj 1.495455 0 Td 39.772727 Tz (consisting ) Tj 63.673469 0 0 63.673469 0 1247.312704 Tm 5.072756 0 Td 47.115385 Tz (genomic ) Tj 2.198718 0 Td 69.80057 Tz (DNA ) Tj 1.429167 0 Td 46.461004 Tz (from ) Tj 1.319231 0 Td 32.719017 Tz (at ) Tj 0.596795 0 Td 35.074786 Tz (least ) Tj 1.25641 0 Td 46.242877 Tz (one ) Tj 1.020833 0 Td 38.739316 Tz (plant ) Tj 1.366346 0 Td 37.517806 Tz (for ) Tj 0.848077 0 Td 39.262821 Tz (the ) Tj 0.895192 0 Td 42.534722 Tz (presence ) Tj 2.245833 0 Td 44.497863 Tz (of ) Tj 0.675321 0 Td 39.262821 Tz (a ) Tj 1.444872 0 Td 44.497863 Tz (of ) Tj 0.675321 0 Td 39.262821 Tz (the ) Tj 0.910897 0 Td 41.007835 Tz (polynucleotides ) Tj 3.926282 0 Td 36.907051 Tz (identified ) Tj 2.402885 0 Td 41.007835 Tz (herein ) Tj 1.680449 0 Td 36.645299 Tz (as ) Tj 0.691026 0 Td 34.027778 Tz (\( ) Tj 0.219872 0 Td 26.175214 Tz (a ) Tj 0.282692 0 Td 26.175214 Tz (\) ) Tj 0.219872 0 Td 26.175214 Tz (- ) Tj 0.204167 0 Td 26.175214 Tz (\( ) Tj 0.141346 0 Td 26.175214 Tz (n ) Tj 0.361218 0 Td 26.175214 Tz (\) ) Tj 0.047115 0 Td 26.175214 Tz (, ) Tj 0.376923 0 Td 43.189103 Tz (with ) Tj 1.225 0 Td 40.135328 Tz (the ) Tj 57.763975 0 0 57.763975 0 1207.931613 Tm 5.574409 0 Td 44.103943 Tz (nucleic ) Tj 2.112043 0 Td 44.000896 Tz (acid ) Tj 1.281075 0 Td 50.973716 Tz (marker ) Tj 2.042796 0 Td 40.394265 Tz (that ) Tj 1.211828 0 Td 31.738351 Tz (is ) Tj 0.640538 0 Td 44.145161 Tz (associated ) Tj 2.856452 0 Td 48.328853 Tz (with ) Tj 1.384946 0 Td 67.323775 Tz (FHB ) Tj 1.471505 0 Td 42.413978 Tz (resistance ) Tj 3.860538 0 Td 45.340502 Tz (proviso ) Tj 2.112043 0 Td 40.394265 Tz (that ) Tj 1.177204 0 Td 42.558244 Tz (said ) Tj 1.211828 0 Td 48.689516 Tz (sequence ) Tj 2.527527 0 Td 33.181004 Tz (is ) Tj 0.588602 0 Td 46.164875 Tz (not ) Tj 1.021398 0 Td 40.394265 Tz (identical ) Tj 2.389032 0 Td 38.951613 Tz (to ) Tj 0.709785 0 Td 64.438471 Tz (SEQ ) Tj 1.367634 0 Td 54.820789 Tz (ID ) Tj 0.84828 0 Td 76.460573 Tz (NO ) Tj 0.986774 0 Td 11.541219 Tz (: ) Tj 0.19043 0 Td 28.853047 Tz (1 ) Tj 0.294301 0 Td 14.426523 Tz (, ) Tj 61.190476 0 0 61.190476 0 1169.228979 Tm 5.262257 0 Td 38.132296 Tz (activity ) Tj 1.863035 0 Td 16.342412 Tz (; ) Tj 0.359533 0 Td 49.027237 Tz (and ) Tj 1.111284 0 Td 27.237354 Tz (\( ) Tj 0.196109 0 Td 43.579767 Tz (b ) Tj 0.326848 0 Td 27.237354 Tz (\) ) Tj 0.392218 0 Td 39.948119 Tz (selecting ) Tj 2.385992 0 Td 35.40856 Tz (at ) Tj 0.653696 0 Td 36.498054 Tz (least ) Tj 1.340078 0 Td 47.211414 Tz (one ) Tj 1.078599 0 Td 40.311284 Tz (plant ) Tj 1.438132 0 Td 45.758755 Tz (comprising ) Tj 2.974319 0 Td 46.303502 Tz (an ) Tj 1.797665 0 Td 42.217899 Tz (or ) Tj 0.719066 0 Td 47.211414 Tz (any ) Tj 1.078599 0 Td 44.124514 Tz (contiguous ) Tj 2.892607 0 Td 44.601167 Tz (fragment ) Tj 2.402335 0 Td 46.303502 Tz (of ) Tj 0.735409 0 Td 61.738003 Tz (SEQ ) Tj 1.405447 0 Td 29.961089 Tz (ID ) Tj 0.768093 0 Td 72.178988 Tz (NO ) Tj 0.931518 0 Td 10.894942 Tz (: ) Tj 0.179767 0 Td 27.237354 Tz (1 ) Tj 0.294163 0 Td 10.894942 Tz (. ) Tj 53.441558 0 0 53.441558 0 1126.645535 Tm 6.043985 0 Td 41.582287 Tz (allele ) Tj 1.740219 0 Td 53.017416 Tz (of ) Tj 0.823329 0 Td 38.983394 Tz (at ) Tj 0.729769 0 Td 41.790198 Tz (least ) Tj 1.515674 0 Td 54.056973 Tz (one ) Tj 1.234994 0 Td 53.017416 Tz (of ) Tj 0.823329 0 Td 46.000405 Tz (said ) Tj 1.328554 0 Td 47.225597 Tz (nucleic ) Tj 2.264156 0 Td 48.339409 Tz (acid ) Tj 1.38469 0 Td 52.571891 Tz (markers ) Tj 2.245443 0 Td 21.830701 Tz (. ) Tj 0.430377 0 Td 46.780073 Tz (In ) Tj 0.823329 0 Td 60.034427 Tz (some ) Tj 3.555286 0 Td 71.729445 Tz (An ) Tj 1.216282 0 Td 44.830903 Tz (isolated ) Tj 2.469988 0 Td 47.671122 Tz (nucleic ) Tj 2.376428 0 Td 48.339409 Tz (acid ) Tj 1.496962 0 Td 51.45808 Tz (of ) Tj 0.879465 0 Td 46.780073 Tz (the ) Tj 1.216282 0 Td 48.512668 Tz (invention ) Tj 2.937789 0 Td 47.715674 Tz (preferably ) Tj 3.237181 0 Td 46.780073 Tz (a ) Tj 60 0 0 60 0 1082.339566 Tm 5.383333 0 Td 50.252525 Tz (embodiments ) Tj 3.516667 0 Td 42.592593 Tz (the ) Tj 0.95 0 Td 42.063492 Tz (nucleic ) Tj 1.983333 0 Td 49.074074 Tz (marker ) Tj 1.95 0 Td 31.944444 Tz (is ) Tj 0.616667 0 Td 41.319444 Tz (selected ) Tj 2.166667 0 Td 50 Tz (from ) Tj 1.383333 0 Td 41.666667 Tz (the ) Tj 0.95 0 Td 47.222222 Tz (group ) Tj 1.816667 0 Td 37.5 Tz (45 ) Tj 0.883333 0 Td 42.063492 Tz (protein ) Tj 1.916667 0 Td 41.049383 Tz (retaining ) Tj 2.383333 0 Td 41.666667 Tz (the ) Tj 0.933333 0 Td 41.388889 Tz (functional ) Tj 2.683333 0 Td 39.074074 Tz (characteristics ) Tj 3.716667 0 Td 47.222222 Tz (of ) Tj 0.65 0 Td 41.666667 Tz (the ) Tj 0.916667 0 Td 42.460317 Tz (protein ) Tj 59.771429 0 0 59.771429 0 1042.675567 Tm 5.40392 0 Td 41.826004 Tz (consisting ) Tj 2.693595 0 Td 47.402804 Tz (of ) Tj 0.702677 0 Td 63.203739 Tz (SEQ ) Tj 1.321702 0 Td 52.979605 Tz (ID ) Tj 0.803059 0 Td 73.892607 Tz (NO ) Tj 0.953633 0 Td 11.153601 Tz (: ) Tj 0.200765 0 Td 27.884003 Tz (1 ) Tj 0.267686 0 Td 13.942001 Tz (, ) Tj 0.284417 0 Td 43.499044 Tz (nucleotide ) Tj 2.810707 0 Td 45.853693 Tz (sequences ) Tj 2.660134 0 Td 46.938071 Tz (having ) Tj 1.873805 0 Td 36.249203 Tz (at ) Tj 1.706501 0 Td 46.938071 Tz (having ) Tj 2.007648 0 Td 41.826004 Tz (the ) Tj 1.087476 0 Td 50.748885 Tz (amino ) Tj 1.873805 0 Td 43.220204 Tz (acid ) Tj 1.371893 0 Td 47.054254 Tz (sequence ) Tj 2.593212 0 Td 47.402804 Tz (of ) Tj 0.85325 0 Td 62.274272 Tz (SEQ ) Tj 1.472275 0 Td 51.585405 Tz (ID ) Tj 0.953633 0 Td 73.892607 Tz (NO ) Tj 0.953633 0 Td 11.153601 Tz (: ) Tj 0.133843 0 Td 41.826004 Tz (3 ) Tj 0.351338 0 Td 11.153601 Tz (. ) Tj 0.41826 0 Td 52.979605 Tz (The ) Tj 60.136054 0 0 60.136054 0 1001.711184 Tm 5.371154 0 Td 37.138009 Tz (least ) Tj 1.346946 0 Td 47.115385 Tz (90 ) Tj 0.598643 0 Td 80.373303 Tz (% ) Tj 0.715045 0 Td 46.768948 Tz (sequence ) Tj 2.444457 0 Td 39.147342 Tz (identity ) Tj 2.07862 0 Td 37.415158 Tz (to ) Tj 0.698416 0 Td 62.820513 Tz (SEQ ) Tj 1.346946 0 Td 51.272624 Tz (ID ) Tj 0.814819 0 Td 73.44457 Tz (NO ) Tj 0.947851 0 Td 11.085973 Tz (: ) Tj 0.199548 0 Td 27.714932 Tz (1 ) Tj 0.266063 0 Td 13.857466 Tz (, ) Tj 0.332579 0 Td 48.963047 Tz (and ) Tj 1.180656 0 Td 40.186652 Tz (contigu- ) Tj 3.226018 0 Td 41.295249 Tz (functional ) Tj 2.860181 0 Td 38.985671 Tz (characteristics ) Tj 3.874548 0 Td 47.115385 Tz (of ) Tj 0.831448 0 Td 41.572398 Tz (the ) Tj 1.097511 0 Td 41.968326 Tz (protein ) Tj 2.095249 0 Td 42.403846 Tz (preferably ) Tj 2.959955 0 Td 65.592006 Tz (com ) Tj 61.298701 0 0 61.298701 0 958.289017 Tm 5.26928 0 Td 45.315443 Tz (ous ) Tj 1.044068 0 Td 44.409134 Tz (fragments ) Tj 2.626483 0 Td 44.862288 Tz (of ) Tj 0.668856 0 Td 42.415254 Tz (nucleotide ) Tj 2.773305 0 Td 44.711237 Tz (sequences ) Tj 2.626483 0 Td 45.768597 Tz (having ) Tj 1.859746 0 Td 35.346045 Tz (at ) Tj 0.636229 0 Td 36.433616 Tz (least ) Tj 1.321398 0 Td 46.221751 Tz (90 ) Tj 0.587288 0 Td 78.84887 Tz (% ) Tj 1.729237 0 Td 38.971281 Tz (prises ) Tj 1.615042 0 Td 40.783898 Tz (the ) Tj 0.9625 0 Td 36.511299 Tz (ability ) Tj 1.729237 0 Td 36.705508 Tz (to ) Tj 0.685169 0 Td 43.04967 Tz (confer ) Tj 1.729237 0 Td 39.96822 Tz (resistance ) Tj 2.610169 0 Td 36.705508 Tz (to ) Tj 0.685169 0 Td 62.535311 Tz (FHB ) Tj 1.19089 0 Td 13.594633 Tz (, ) Tj 0.342585 0 Td 33.986582 Tz (e.g. ) Tj 0.897246 0 Td 13.594633 Tz (, ) Tj 0.309958 0 Td 45.056497 Tz (through ) Tj 61.176471 0 0 61.176471 0 917.607642 Tm 5.279808 0 Td 45.973558 Tz (sequence ) Tj 2.419231 0 Td 38.481571 Tz (identity ) Tj 2.043269 0 Td 36.778846 Tz (to ) Tj 0.702885 0 Td 61.752137 Tz (SEQ ) Tj 1.324038 0 Td 51.762821 Tz (ID ) Tj 0.817308 0 Td 73.557692 Tz (NO ) Tj 0.948077 0 Td 10.897436 Tz (: ) Tj 0.179808 0 Td 27.24359 Tz (1 ) Tj 0.294231 0 Td 10.897436 Tz (. ) Tj 0.310577 0 Td 40.865385 Tz (In ) Tj 0.719231 0 Td 51.762821 Tz (some ) Tj 1.454808 0 Td 49.5338 Tz (embodiments ) Tj 3.252885 0 Td 24.519231 Tz (, ) Tj 1.438462 0 Td 49.038462 Tz (an ) Tj 0.784615 0 Td 40.865385 Tz (antifungal ) Tj 2.680769 0 Td 37.119391 Tz (activity ) Tj 1.781731 0 Td 27.24359 Tz (. ) Tj 58.685714 0 0 58.685714 0 874.558401 Tm 5.486855 0 Td 42.599805 Tz (the ) Tj 0.937196 0 Td 42.031808 Tz (plant ) Tj 1.431353 0 Td 53.959753 Tz (whose ) Tj 1.806232 0 Td 51.119766 Tz (genomic ) Tj 2.351509 0 Td 75.732987 Tz (DNA ) Tj 1.499513 0 Td 31.239857 Tz (is ) Tj 0.596397 0 Td 45.794791 Tz (screened ) Tj 2.368549 0 Td 41.179812 Tz (in ) Tj 0.664557 0 Td 40.469815 Tz (step ) Tj 1.192795 0 Td 28.39987 Tz (\( ) Tj 0.187439 0 Td 42.599805 Tz (a ) Tj 0.289679 0 Td 28.39987 Tz (\) ) Tj 0.374878 0 Td 50.173104 Tz (and ) Tj 0.988315 0 Td 19.879909 Tz (/ ) Tj 0.153359 0 Td 39.759818 Tz (or ) Tj 0.869036 0 Td 38.339825 Tz (50 ) Tj 1.533593 0 Td 44.019799 Tz (In ) Tj 0.681597 0 Td 40.976956 Tz (certain ) Tj 1.857352 0 Td 43.230913 Tz (preferred ) Tj 2.487829 0 Td 51.119766 Tz (embodiments ) Tj 3.390944 0 Td 25.559883 Tz (, ) Tj 0.340798 0 Td 49.699773 Tz (an ) Tj 0.749757 0 Td 41.179812 Tz (isolated ) Tj 2.11295 0 Td 43.005518 Tz (nucleic ) Tj 1.993671 0 Td 43.309802 Tz (acid ) Tj 59.940476 0 0 59.940476 0 835.142857 Tm 5.371996 0 Td 41.708044 Tz (the ) Tj 1.000993 0 Td 34.756703 Tz (at ) Tj 0.667329 0 Td 37.259186 Tz (least ) Tj 1.351341 0 Td 49.122807 Tz (one ) Tj 1.101092 0 Td 41.708044 Tz (plant ) Tj 1.50149 0 Td 41.360477 Tz (selected ) Tj 2.218868 0 Td 38.927507 Tz (in ) Tj 0.717378 0 Td 38.927507 Tz (step ) Tj 1.217875 0 Td 30.585899 Tz (\( ) Tj 0.266931 0 Td 27.805362 Tz (b ) Tj 0.233565 0 Td 27.805362 Tz (\) ) Tj 0.433764 0 Td 30.585899 Tz (is ) Tj 0.633962 0 Td 41.708044 Tz (a ) Tj 0.46713 0 Td 41.708044 Tz (plant ) Tj 1.484806 0 Td 50.049652 Tz (from ) Tj 1.434757 0 Td 41.708044 Tz (a ) Tj 1.534856 0 Td 47.269116 Tz (of ) Tj 0.817478 0 Td 40.781198 Tz (the ) Tj 1.067726 0 Td 43.252786 Tz (invention ) Tj 2.652632 0 Td 46.033322 Tz (comprises ) Tj 2.819464 0 Td 41.708044 Tz (a ) Tj 0.567229 0 Td 44.09136 Tz (polynucleotide ) Tj 4.037339 0 Td 46.921549 Tz (sequence ) Tj 2.569215 0 Td 36.146971 Tz (at ) Tj 56.108374 0 0 56.108374 0 795.137034 Tm 5.738894 0 Td 47.527071 Tz (population ) Tj 3.332836 0 Td 47.85712 Tz (generated ) Tj 3.047673 0 Td 53.467954 Tz (by ) Tj 1.14065 0 Td 44.556629 Tz (a ) Tj 0.766374 0 Td 43.96254 Tz (cross ) Tj 1.407989 0 Td 11.881768 Tz (. ) Tj 0.588147 0 Td 46.04185 Tz (In ) Tj 1.015891 0 Td 42.859233 Tz (certain ) Tj 2.263477 0 Td 45.546776 Tz (preferred ) Tj 3.814047 0 Td 39.803922 Tz (least ) Tj 1.407989 0 Td 49.012291 Tz (95 ) Tj 0.641615 0 Td 86.142815 Tz (% ) Tj 0.730729 0 Td 41.586187 Tz (identical ) Tj 2.441703 0 Td 41.586187 Tz (to ) Tj 0.730729 0 Td 66.339869 Tz (SEQ ) Tj 1.407989 0 Td 54.953175 Tz (ID ) Tj 0.855487 0 Td 78.716711 Tz (NO ) Tj 1.015891 0 Td 11.881768 Tz (: ) Tj 0.196049 0 Td 29.704419 Tz (1 ) Tj 0.302985 0 Td 14.85221 Tz (, ) Tj 0.302985 0 Td 47.527071 Tz (2 ) Tj 0.356453 0 Td 14.85221 Tz (, ) Tj 0.320808 0 Td 47.527071 Tz (4 ) Tj 0.356453 0 Td 14.85221 Tz (, ) Tj 0.320808 0 Td 41.586187 Tz (5 ) Tj 0.481212 0 Td 46.04185 Tz (or ) Tj 0.748551 0 Td 44.556629 Tz (6 ) Tj 0.33863 0 Td 14.85221 Tz (, ) Tj 0.285162 0 Td 45.447761 Tz (preferably ) Tj 60.37594 0 0 60.37594 0 751.500966 Tm 5.349813 0 Td 50.441526 Tz (embodiments ) Tj 3.296015 0 Td 24.844334 Tz (, ) Tj 0.397509 0 Td 41.407223 Tz (the ) Tj 0.960648 0 Td 51.528989 Tz (method ) Tj 2.070361 0 Td 31.745538 Tz (is ) Tj 0.62939 0 Td 42.984641 Tz (applied ) Tj 2.00411 0 Td 38.646741 Tz (to ) Tj 0.695641 0 Td 49.136571 Tz (wheat ) Tj 1.705978 0 Td 41.407223 Tz (or ) Tj 0.695641 0 Td 42.787464 Tz (barley ) Tj 1.474097 0 Td 27.604815 Tz (. ) Tj 2.186301 0 Td 41.407223 Tz (a ) Tj 0.447198 0 Td 43.77335 Tz (polynucleotide ) Tj 3.908842 0 Td 46.238066 Tz (sequence ) Tj 2.451308 0 Td 41.062163 Tz (selected ) Tj 2.169738 0 Td 48.998547 Tz (from ) Tj 1.391283 0 Td 40.487062 Tz (the ) Tj 0.944085 0 Td 46.928186 Tz (group ) Tj 1.672852 0 Td 44.956413 Tz (consist ) Tj 57.771429 0 0 57.771429 0 709.018717 Tm 6.248764 0 Td 43.273986 Tz (In ) Tj 0.675074 0 Td 50.005495 Tz (one ) Tj 1.073195 0 Td 43.273986 Tz (or ) Tj 0.657765 0 Td 54.813716 Tz (more ) Tj 1.488625 0 Td 52.19105 Tz (embodiments ) Tj 3.617705 0 Td 49.043851 Tz (of ) Tj 0.675074 0 Td 43.273986 Tz (the ) Tj 0.934718 0 Td 43.594534 Tz (invention ) Tj 2.406034 0 Td 25.964392 Tz (, ) Tj 0.328882 0 Td 43.273986 Tz (the ) Tj 0.934718 0 Td 49.043851 Tz (markers ) Tj 3.40999 0 Td 44.23563 Tz (ing ) Tj 1.038576 0 Td 49.043851 Tz (of ) Tj 0.778932 0 Td 64.430157 Tz (SEQ ) Tj 1.419387 0 Td 53.37125 Tz (ID ) Tj 0.882789 0 Td 76.450709 Tz (NO ) Tj 0.986647 0 Td 11.53973 Tz (: ) Tj 0.138477 0 Td 46.158919 Tz (2 ) Tj 0.346192 0 Td 14.424662 Tz (, ) Tj 0.363501 0 Td 46.158919 Tz (4 ) Tj 0.346192 0 Td 14.424662 Tz (, ) Tj 0.363501 0 Td 40.389054 Tz (5 ) Tj 0.519288 0 Td 44.716452 Tz (or ) Tj 0.778932 0 Td 43.273986 Tz (6 ) Tj 0.346192 0 Td 11.53973 Tz (. ) Tj 57.083333 0 0 57.083333 0 668.743729 Tm 5.658394 0 Td 49.635036 Tz (of ) Tj 0.770803 0 Td 42.919708 Tz (resistance ) Tj 2.837956 0 Td 45.046924 Tz (include ) Tj 2.172263 0 Td 49.635036 Tz (an ) Tj 0.840876 0 Td 52.554745 Tz (Fhb1 ) Tj 1.594161 0 Td 50.364964 Tz (gene ) Tj 1.454015 0 Td 49.148418 Tz (having ) Tj 2.067153 0 Td 65.206813 Tz (SEQ ) Tj 1.454015 0 Td 54.014599 Tz (ID ) Tj 0.910949 0 Td 77.372263 Tz (NO ) Tj 0.99854 0 Td 11.678832 Tz (: ) Tj 0.192701 0 Td 29.19708 Tz (1 ) Tj 0.29781 0 Td 14.59854 Tz (, ) Tj 0.560584 0 Td 36.49635 Tz (55 ) Tj 1.541606 0 Td 45.255474 Tz (In ) Tj 0.875912 0 Td 47.13243 Tz (general ) Tj 1.874453 0 Td 26.277372 Tz (, ) Tj 0.508029 0 Td 43.79562 Tz (the ) Tj 1.121168 0 Td 45.046924 Tz (present ) Tj 2.224818 0 Td 45.41768 Tz (invention ) Tj 2.80292 0 Td 44.525547 Tz (includes ) Tj 2.487591 0 Td 51.581509 Tz (any ) Tj 1.278832 0 Td 51.581509 Tz (and ) Tj 1.261314 0 Td 34.06326 Tz (all ) Tj 63.642857 0 0 63.642857 0 625.774566 Tm 5.090909 0 Td 43.064389 Tz (sequences ) Tj 2.514029 0 Td 44.082803 Tz (having ) Tj 1.775533 0 Td 32.734755 Tz (at ) Tj 0.581369 0 Td 35.091657 Tz (least ) Tj 1.241302 0 Td 45.828657 Tz (90 ) Tj 0.581369 0 Td 75.944632 Tz (% ) Tj 0.659933 0 Td 43.864572 Tz (sequence ) Tj 2.294052 0 Td 36.662926 Tz (identity ) Tj 1.93266 0 Td 35.353535 Tz (to ) Tj 0.64422 0 Td 59.359022 Tz (SEQ ) Tj 1.257015 0 Td 48.447437 Tz (ID ) Tj 1.791246 0 Td 41.37673 Tz (kinds ) Tj 1.52413 0 Td 43.209877 Tz (of ) Tj 0.691358 0 Td 43.209877 Tz (manipulation ) Tj 3.346801 0 Td 44.519267 Tz (of ) Tj 0.707071 0 Td 39.281706 Tz (the ) Tj 0.958474 0 Td 47.138047 Tz (Fhbl ) Tj 1.429854 0 Td 39.655817 Tz (nucleic ) Tj 1.948373 0 Td 38.75795 Tz (acids ) Tj 1.414141 0 Td 43.537224 Tz (provided ) Tj 62.619048 0 0 62.619048 0 584.680824 Tm 5.142205 0 Td 70.532319 Tz (NO ) Tj 0.910266 0 Td 10.646388 Tz (: ) Tj 0.191635 0 Td 26.61597 Tz (1 ) Tj 0.255513 0 Td 13.307985 Tz (, ) Tj 0.303422 0 Td 47.021546 Tz (and ) Tj 1.038023 0 Td 43.768483 Tz (sequences ) Tj 2.555133 0 Td 44.803549 Tz (having ) Tj 1.804563 0 Td 34.60076 Tz (at ) Tj 0.606844 0 Td 35.665399 Tz (least ) Tj 1.277567 0 Td 45.247148 Tz (50 ) Tj 0.574905 0 Td 77.186312 Tz (% ) Tj 0.686692 0 Td 44.581749 Tz (sequence ) Tj 2.331559 0 Td 37.595057 Tz (identity ) Tj 3.018251 0 Td 40.811153 Tz (herein ) Tj 1.453232 0 Td 23.954373 Tz (, ) Tj 0.447148 0 Td 41.106886 Tz (including ) Tj 2.267681 0 Td 13.307985 Tz (, ) Tj 0.351331 0 Td 43.346008 Tz (without ) Tj 2.076046 0 Td 36.996198 Tz (limitation ) Tj 2.28365 0 Td 23.954373 Tz (, ) Tj 0.415209 0 Td 47.908745 Tz (by ) Tj 0.830418 0 Td 50.038023 Tz (means ) Tj 1.772624 0 Td 45.247148 Tz (of ) Tj 0.734601 0 Td 40.304183 Tz (genetic ) Tj 60.714286 0 0 60.714286 0 542.649457 Tm 5.336471 0 Td 62.222222 Tz (SEQ ) Tj 1.432941 0 Td 50.784314 Tz (ID ) Tj 0.905882 0 Td 72.745098 Tz (NO ) Tj 0.938824 0 Td 10.980392 Tz (: ) Tj 0.181176 0 Td 27.45098 Tz (1 ) Tj 0.28 0 Td 13.72549 Tz (, ) Tj 0.395294 0 Td 47.45098 Tz (wherein ) Tj 2.256471 0 Td 40.627451 Tz (there ) Tj 1.531765 0 Td 30.196078 Tz (is ) Tj 0.691765 0 Td 34.313725 Tz (at ) Tj 0.708235 0 Td 37.333333 Tz (least ) Tj 1.432941 0 Td 43.921569 Tz (95 ) Tj 0.592941 0 Td 79.607843 Tz (% ) Tj 0.790588 0 Td 38.77451 Tz (identity ) Tj 2.157647 0 Td 39.803922 Tz (in ) Tj 1.729412 0 Td 43.672014 Tz (engineering ) Tj 3.129412 0 Td 43.647059 Tz (techniques ) Tj 2.882353 0 Td 38.431373 Tz (to ) Tj 0.724706 0 Td 48.954248 Tz (modify ) Tj 2.025882 0 Td 41.176471 Tz (the ) Tj 1.004706 0 Td 47.352941 Tz (gene ) Tj 1.152941 0 Td 19.215686 Tz (, ) Tj 0.411765 0 Td 41.519608 Tz (increase ) Tj 2.256471 0 Td 48.72549 Tz (copy ) Tj 57.012987 0 0 57.012987 0 501.291299 Tm 5.647836 0 Td 44.215072 Tz (residues ) Tj 2.315262 0 Td 51.523349 Tz (69-377,2330-2734 ) Tj 5.016401 0 Td 14.616553 Tz (, ) Tj 0.280638 0 Td 43.849658 Tz (or ) Tj 0.666515 0 Td 51.645153 Tz (2816-3103 ) Tj 2.981777 0 Td 54.081245 Tz (of ) Tj 0.666515 0 Td 65.287269 Tz (SEQ ) Tj 1.403189 0 Td 54.081245 Tz (ID ) Tj 0.806834 0 Td 77.46773 Tz (NO ) Tj 0.999772 0 Td 11.693242 Tz (: ) Tj 0.192938 0 Td 29.233106 Tz (1 ) Tj 0.315718 0 Td 11.693242 Tz (. ) Tj 1.438269 0 Td 56.030119 Tz (number ) Tj 2.350342 0 Td 43.849658 Tz (or ) Tj 0.859453 0 Td 45.798532 Tz (increased ) Tj 2.806378 0 Td 44.726651 Tz (expression ) Tj 2.771298 0 Td 29.233106 Tz (, ) Tj 0.508656 0 Td 51.888762 Tz (gene ) Tj 1.31549 0 Td 29.233106 Tz (- ) Tj 0.140319 0 Td 49.696279 Tz (based ) Tj 1.806606 0 Td 49.696279 Tz (markers ) Tj 2.455581 0 Td 41.900785 Tz (for ) Tj 61.428571 0 0 61.428571 0 456.190114 Tm 5.25814 0 Td 42.054264 Tz (In ) Tj 0.7 0 Td 47.028424 Tz (one ) Tj 1.05814 0 Td 42.054264 Tz (or ) Tj 0.683721 0 Td 51.550388 Tz (more ) Tj 1.448837 0 Td 49.577167 Tz (embodiments ) Tj 3.255814 0 Td 24.418605 Tz (, ) Tj 0.35814 0 Td 40.697674 Tz (the ) Tj 0.927907 0 Td 46.124031 Tz (markers ) Tj 2.165116 0 Td 46.124031 Tz (of ) Tj 0.683721 0 Td 39.883721 Tz (resistance ) Tj 2.604651 0 Td 39.793282 Tz (are ) Tj 1.123256 0 Td 35.271318 Tz (60 ) Tj 0.830233 0 Td 44.089147 Tz (breeding ) Tj 2.44186 0 Td 47.932817 Tz (and ) Tj 1.155814 0 Td 46.666667 Tz (pyramiding ) Tj 3.109302 0 Td 45.445736 Tz (with ) Tj 1.4 0 Td 41.24031 Tz (other ) Tj 1.546512 0 Td 44.496124 Tz (genes ) Tj 1.676744 0 Td 38.888889 Tz (for ) Tj 1.009302 0 Td 42.204996 Tz (increased ) Tj 61.666667 0 0 61.666667 0 417.802244 Tm 5.254054 0 Td 40.202703 Tz (selected ) Tj 2.416216 0 Td 48.648649 Tz (from ) Tj 1.654054 0 Td 40.540541 Tz (the ) Tj 1.232432 0 Td 45.945946 Tz (group ) Tj 1.897297 0 Td 40.540541 Tz (consisting ) Tj 2.951351 0 Td 43.243243 Tz (of ) Tj 0.518919 0 Td 18.918919 Tz (: ) Tj 0.616216 0 Td 41.312741 Tz (nucleic ) Tj 2.254054 0 Td 41.891892 Tz (acid ) Tj 2.237838 0 Td 63.063063 Tz (FHB ) Tj 1.475676 0 Td 39.72973 Tz (resistance ) Tj 2.448649 0 Td 10.810811 Tz (. ) Tj 0.437838 0 Td 45.945946 Tz (For ) Tj 1.151351 0 Td 48.262548 Tz (example ) Tj 2.367568 0 Td 41.891892 Tz (fusion ) Tj 1.816216 0 Td 40.202703 Tz (proteins ) Tj 2.286486 0 Td 41.891892 Tz (or ) Tj 0.810811 0 Td 41.312741 Tz (vectors ) Tj 64.285714 0 0 64.285714 0 378.609394 Tm 5.024444 0 Td 42.633745 Tz (sequences ) Tj 2.551111 0 Td 43.814815 Tz (comprising ) Tj 2.582222 0 Td 25.925926 Tz (, ) Tj 0.373333 0 Td 38.37037 Tz (consisting ) Tj 2.333333 0 Td 25.925926 Tz (, ) Tj 0.404444 0 Td 38.888889 Tz (or ) Tj 0.684444 0 Td 38.888889 Tz (consisting ) Tj 2.551111 0 Td 37.239057 Tz (essentially ) Tj 3.671111 0 Td 43.75 Tz (encoding ) Tj 2.333333 0 Td 37.160494 Tz (for ) Tj 0.871111 0 Td 40.185185 Tz (fusion ) Tj 1.633333 0 Td 38.564815 Tz (proteins ) Tj 2.1 0 Td 37.160494 Tz (for ) Tj 0.871111 0 Td 40.329218 Tz (increased ) Tj 2.395556 0 Td 60.493827 Tz (FHB ) Tj 1.306667 0 Td 38.111111 Tz (resistance ) Tj 2.333333 0 Td 12.962963 Tz (, ) Tj 59.828571 0 0 59.828571 0 335.876777 Tm 5.398758 0 Td 47.357529 Tz (of ) Tj 0.86915 0 Td 63.143373 Tz (SEQ ) Tj 1.504298 0 Td 52.929004 Tz (ID ) Tj 0.986151 0 Td 73.822031 Tz (NO ) Tj 0.952722 0 Td 11.142948 Tz (: ) Tj 0.133715 0 Td 44.571792 Tz (4 ) Tj 0.334288 0 Td 13.928685 Tz (, ) Tj 0.484718 0 Td 39.000318 Tz (5 ) Tj 0.317574 0 Td 13.928685 Tz (, ) Tj 0.468004 0 Td 43.178924 Tz (or ) Tj 0.885864 0 Td 41.786055 Tz (6 ) Tj 0.30086 0 Td 13.928685 Tz (, ) Tj 0.484718 0 Td 49.214687 Tz (and ) Tj 1.220153 0 Td 42.184018 Tz (nucleic ) Tj 2.15616 0 Td 43.178924 Tz (acid ) Tj 1.404011 0 Td 45.809898 Tz (sequences ) Tj 3.760745 0 Td 45.190845 Tz (according ) Tj 2.590735 0 Td 39.000318 Tz (to ) Tj 0.635148 0 Td 41.786055 Tz (the ) Tj 0.952722 0 Td 45.809898 Tz (sequences ) Tj 2.657593 0 Td 44.262266 Tz (described ) Tj 2.523878 0 Td 39.928897 Tz (herein ) Tj 1.554441 0 Td 25.071633 Tz (, ) Tj 0.334288 0 Td 40.393187 Tz (in ) Tj 0.635148 0 Td 47.104281 Tz (combination ) Tj 59.375 0 0 59.375 0 297.272271 Tm 5.423158 0 Td 48.421053 Tz (encoding ) Tj 2.661053 0 Td 39.298246 Tz (a ) Tj 0.606316 0 Td 41.704261 Tz (protein ) Tj 2.088421 0 Td 46.315789 Tz (comprising ) Tj 2.795789 0 Td 28.070175 Tz (, ) Tj 0.538947 0 Td 41.54386 Tz (consisting ) Tj 2.492632 0 Td 28.070175 Tz (, ) Tj 0.538947 0 Td 44.912281 Tz (or ) Tj 0.875789 0 Td 42.105263 Tz (consisting ) Tj 3.806316 0 Td 47.017544 Tz (with ) Tj 1.330526 0 Td 42.666667 Tz (other ) Tj 1.482105 0 Td 41.793372 Tz (desirable ) Tj 2.458947 0 Td 49.964912 Tz (wheat ) Tj 1.717895 0 Td 39.48538 Tz (characteristics ) Tj 3.789474 0 Td 42.105263 Tz (are ) Tj 0.976842 0 Td 47.017544 Tz (contemplated ) Tj 60 0 0 60 0 252.51532 Tm 5.383333 0 Td 39.393939 Tz (essentially ) Tj 2.883333 0 Td 47.222222 Tz (of ) Tj 0.783333 0 Td 62.037037 Tz (SEQ ) Tj 1.4 0 Td 52.777778 Tz (ID ) Tj 0.883333 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.15 0 Td 44.444444 Tz (7 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 0.4 0 Td 41.666667 Tz (8 ) Tj 0.3 0 Td 13.888889 Tz (, ) Tj 0.383333 0 Td 43.055556 Tz (or ) Tj 0.783333 0 Td 33.333333 Tz (9. ) Tj 0.7 0 Td 51.851852 Tz (The ) Tj 1.183333 0 Td 52.314815 Tz (method ) Tj 2.133333 0 Td 40.47619 Tz (further ) Tj 2.1 0 Td 34.722222 Tz (65 ) Tj 0.85 0 Td 51.388889 Tz (by ) Tj 0.833333 0 Td 41.666667 Tz (the ) Tj 0.966667 0 Td 42.857143 Tz (present ) Tj 2.016667 0 Td 41.975309 Tz (invention ) Tj 2.4 0 Td 19.444444 Tz (. ) Tj 60.357143 0 0 60.357143 0 212.031496 Tm 5.351479 0 Td 45.715538 Tz (comprises ) Tj 2.849704 0 Td 39.88604 Tz (selecting ) Tj 2.485207 0 Td 40.499671 Tz (plants ) Tj 1.789349 0 Td 46.482577 Tz (having ) Tj 2.021302 0 Td 48.783695 Tz (one ) Tj 1.209467 0 Td 42.800789 Tz (or ) Tj 0.811834 0 Td 53.155819 Tz (more ) Tj 1.607101 0 Td 46.942801 Tz (of ) Tj 0.811834 0 Td 42.524655 Tz (these ) Tj 3.164497 0 Td 52.465483 Tz (The ) Tj 1.143195 0 Td 42.60355 Tz (present ) Tj 2.004734 0 Td 42.954197 Tz (invention ) Tj 2.518343 0 Td 40.039448 Tz (also ) Tj 1.176331 0 Td 44.18146 Tz (provides ) Tj 2.336095 0 Td 46.69177 Tz (recombinant ) Tj 3.280473 0 Td 42.209073 Tz (vectors ) Tj 55.986395 0 0 55.986395 0 170.738095 Tm 5.751397 0 Td 50.607533 Tz (markers ) Tj 2.447023 0 Td 50.607533 Tz (of ) Tj 0.821628 0 Td 43.165249 Tz (resistance ) Tj 2.643499 0 Td 20.838396 Tz (. ) Tj 0.446537 0 Td 55.569056 Tz (The ) Tj 1.32175 0 Td 46.307547 Tz (invention ) Tj 2.804253 0 Td 32.746051 Tz (is ) Tj 0.714459 0 Td 43.165249 Tz (also ) Tj 1.339611 0 Td 48.481166 Tz (broadly ) Tj 2.4113 0 Td 46.142163 Tz (con- ) Tj 2.429162 0 Td 41.676792 Tz (that ) Tj 1.196719 0 Td 45.73622 Tz (incorporate ) Tj 3.232928 0 Td 50.607533 Tz (an ) Tj 0.803767 0 Td 43.165249 Tz (isolated ) Tj 2.250547 0 Td 45.078979 Tz (nucleic ) Tj 2.125516 0 Td 45.397934 Tz (acid ) Tj 1.286027 0 Td 50.607533 Tz (of ) Tj 0.714459 0 Td 44.653706 Tz (the ) Tj 1.018104 0 Td 45.646011 Tz (invention ) Tj 2.500608 0 Td 23.81531 Tz (. ) Tj 0.375091 0 Td 44.653706 Tz (In ) Tj ET Q endstream endobj 173 0 obj << /Length 1 >> stream q endstream endobj 174 0 obj << /Length 55950 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 48.571429 0 0 48.571429 0 2973 Tm 15.626471 0 Td 75.490196 Tz (5 ) Tj 48.571429 0 0 48.571429 0 2971 Tm 35.679412 0 Td 75.490196 Tz (6 ) Tj 62 0 0 62 0 2911.478373 Tm 5.225806 0 Td 51.075269 Tz (some ) Tj 1.564516 0 Td 48.631476 Tz (embodiments ) Tj 3.532258 0 Td 40.322581 Tz (the ) Tj 1.048387 0 Td 38.642473 Tz (isolated ) Tj 2.16129 0 Td 40.706605 Tz (nucleic ) Tj 2.048387 0 Td 41.666667 Tz (acid ) Tj 1.306452 0 Td 29.569892 Tz (is ) Tj 0.693548 0 Td 43.682796 Tz (operably ) Tj 3.322581 0 Td 40.706605 Tz (nucleic ) Tj 1.903226 0 Td 41.666667 Tz (acid ) Tj 1.145161 0 Td 44.892473 Tz (comprising ) Tj 2.870968 0 Td 40.322581 Tz (a ) Tj 0.403226 0 Td 40.706605 Tz (nucleic ) Tj 1.903226 0 Td 40.994624 Tz (acid ) Tj 1.145161 0 Td 45.698925 Tz (of ) Tj 0.629032 0 Td 40.322581 Tz (the ) Tj 0.903226 0 Td 40.023895 Tz (invention ) Tj 2.225806 0 Td 24.193548 Tz (, ) Tj 0.354839 0 Td 33.602151 Tz (e.g. ) Tj 0.887097 0 Td 13.44086 Tz (, ) Tj 61.168831 0 0 61.168831 0 2872.660784 Tm 5.280467 0 Td 42.232838 Tz (linked ) Tj 1.863694 0 Td 38.145789 Tz (to ) Tj 0.850106 0 Td 40.870488 Tz (a ) Tj 0.604883 0 Td 43.595188 Tz (heterologous ) Tj 3.514862 0 Td 46.660474 Tz (promoter ) Tj 2.223355 0 Td 24.522293 Tz (. ) Tj 0.506794 0 Td 42.232838 Tz (In ) Tj 0.866454 0 Td 39.313517 Tz (certain ) Tj 1.99448 0 Td 41.778721 Tz (preferred ) Tj 3.498514 0 Td 47.682236 Tz (an ) Tj 0.752017 0 Td 48.363411 Tz (Fhbl ) Tj 1.422293 0 Td 41.259731 Tz (nucleic ) Tj 1.945435 0 Td 42.232838 Tz (acid ) Tj 1.046285 0 Td 13.623496 Tz (, ) Tj 0.294268 0 Td 36.783439 Tz (to ) Tj 0.670276 0 Td 46.319887 Tz (an ) Tj 0.752017 0 Td 62.668082 Tz (FHB ) Tj 1.193418 0 Td 24.522293 Tz (- ) Tj 0.212527 0 Td 40.375088 Tz (susceptible ) Tj 2.860934 0 Td 40.870488 Tz (plant ) Tj 1.17707 0 Td 27.246992 Tz (, ) Tj 0.376008 0 Td 46.70913 Tz (wherein ) Tj 60 0 0 60 0 2830.521208 Tm 5.383333 0 Td 50.252525 Tz (embodiments ) Tj 3.666667 0 Td 41.666667 Tz (the ) Tj 1.083333 0 Td 44.212963 Tz (heterologous ) Tj 3.533333 0 Td 47.916667 Tz (promoter ) Tj 2.616667 0 Td 31.944444 Tz (is ) Tj 0.733333 0 Td 41.666667 Tz (functional ) Tj 2.85 0 Td 40.277778 Tz (in ) Tj 1.766667 0 Td 40.972222 Tz (said ) Tj 1.183333 0 Td 39.930556 Tz (transfer ) Tj 2.133333 0 Td 47.222222 Tz (of ) Tj 0.75 0 Td 40.972222 Tz (said ) Tj 1.183333 0 Td 42.460317 Tz (nucleic ) Tj 2.033333 0 Td 43.055556 Tz (acid ) Tj 1.25 0 Td 31.944444 Tz (is ) Tj 0.616667 0 Td 48.148148 Tz (performed ) Tj 2.816667 0 Td 51.388889 Tz (by ) Tj 0.85 0 Td 44.791667 Tz (transfor ) Tj 62.342857 0 0 62.342857 0 2790.374177 Tm 5.164986 0 Td 39.209695 Tz (plants ) Tj 1.636114 0 Td 44.556472 Tz (and ) Tj 0.930339 0 Td 21.387107 Tz (/ ) Tj 0.160403 0 Td 36.090742 Tz (or ) Tj 0.625573 0 Td 30.743966 Tz (is ) Tj 0.593492 0 Td 45.065689 Tz (induced ) Tj 2.085243 0 Td 48.12099 Tz (by ) Tj 0.785976 0 Td 40.100825 Tz (a ) Tj 0.449129 0 Td 44.445081 Tz (pathogen ) Tj 2.149404 0 Td 26.733883 Tz (, ) Tj 0.384968 0 Td 38.318566 Tz (particularly ) Tj 2.967461 0 Td 40.100825 Tz (a ) Tj 0.433089 0 Td 40.100825 Tz (plant ) Tj 2.42209 0 Td 46.338731 Tz (mation ) Tj 1.700275 0 Td 13.366942 Tz (, ) Tj 0.384968 0 Td 49.457684 Tz (by ) Tj 0.898258 0 Td 41.103346 Tz (crossing ) Tj 2.005041 0 Td 13.366942 Tz (, ) Tj 0.401008 0 Td 49.457684 Tz (by ) Tj 0.866178 0 Td 40.100825 Tz (protoplast ) Tj 2.694775 0 Td 40.54639 Tz (fusion ) Tj 1.491751 0 Td 24.060495 Tz (, ) Tj 0.417049 0 Td 49.457684 Tz (by ) Tj 0.882218 0 Td 40.100825 Tz (a ) Tj 0.545371 0 Td 51.558203 Tz (doubled ) Tj 61.428571 0 0 61.428571 0 2747.986301 Tm 5.24186 0 Td 45.784884 Tz (pathogen ) Tj 2.213953 0 Td 27.131783 Tz (. ) Tj 0.553488 0 Td 40.697674 Tz (In ) Tj 0.87907 0 Td 51.550388 Tz (some ) Tj 1.595349 0 Td 41.602067 Tz (preferred ) Tj 2.604651 0 Td 49.82382 Tz (embodiments ) Tj 3.272093 0 Td 24.418605 Tz (, ) Tj 0.504651 0 Td 40.697674 Tz (the ) Tj 1.123256 0 Td 39.341085 Tz (isolated ) Tj 2.376744 0 Td 29.844961 Tz (5 ) Tj 0.732558 0 Td 43.410853 Tz (haploid ) Tj 2.067442 0 Td 43.712317 Tz (technique ) Tj 2.62093 0 Td 42.054264 Tz (or ) Tj 0.732558 0 Td 50.193798 Tz (by ) Tj 0.862791 0 Td 50.645995 Tz (embryo ) Tj 2.083721 0 Td 42.958656 Tz (rescue ) Tj 1.611628 0 Td 10.852713 Tz (. ) Tj 0.35814 0 Td 40.697674 Tz (In ) Tj 0.765116 0 Td 51.550388 Tz (some ) Tj 1.595349 0 Td 53.81137 Tz (embodi ) Tj 61.278195 0 0 61.278195 0 2707.800639 Tm 5.254724 0 Td 41.96319 Tz (nucleic ) Tj 2.023558 0 Td 40.797546 Tz (acid ) Tj 1.240245 0 Td 45.330607 Tz (comprises ) Tj 2.774233 0 Td 32.638037 Tz (a ) Tj 0.456933 0 Td 43.128834 Tz (polynucleotide ) Tj 3.916564 0 Td 45.55726 Tz (sequence ) Tj 2.447853 0 Td 32.638037 Tz (at ) Tj 0.718037 0 Td 35.90184 Tz (least ) Tj 2.317301 0 Td 49.501022 Tz (ments ) Tj 1.485031 0 Td 21.758691 Tz (, ) Tj 0.359018 0 Td 44.877301 Tz (such ) Tj 1.289202 0 Td 40.797546 Tz (a ) Tj 0.440613 0 Td 51.223586 Tz (method ) Tj 2.056196 0 Td 39.243354 Tz (further ) Tj 1.844049 0 Td 45.028403 Tz (comprises ) Tj 2.692638 0 Td 38.621677 Tz (steps ) Tj 1.403436 0 Td 43.517382 Tz (of ) Tj 0.522209 0 Td 19.038855 Tz (: ) Tj 0.342699 0 Td 41.09975 Tz (detecting ) Tj 57.402597 0 0 57.402597 0 2663.740822 Tm 5.644344 0 Td 47.90724 Tz (95 ) Tj 0.64457 0 Td 84.200603 Tz (% ) Tj 0.905882 0 Td 40.648567 Tz (identical ) Tj 2.595701 0 Td 39.196833 Tz (to ) Tj 0.905882 0 Td 65.811966 Tz (SEQ ) Tj 1.585294 0 Td 55.165913 Tz (ID ) Tj 1.045249 0 Td 76.941931 Tz (NO ) Tj 0.992986 0 Td 11.613876 Tz (: ) Tj 0.191629 0 Td 29.034691 Tz (1 ) Tj 0.296154 0 Td 14.517345 Tz (, ) Tj 0.522624 0 Td 46.455505 Tz (2 ) Tj 0.330995 0 Td 14.517345 Tz (, ) Tj 0.522624 0 Td 46.455505 Tz (4 ) Tj 0.348416 0 Td 14.517345 Tz (, ) Tj 0.522624 0 Td 40.648567 Tz (5 ) Tj 0.679412 0 Td 45.003771 Tz (or ) Tj 0.940724 0 Td 43.552036 Tz (6 ) Tj 0.313575 0 Td 14.517345 Tz (, ) Tj 0.522624 0 Td 37.019231 Tz (e.g. ) Tj 0.958145 0 Td 14.517345 Tz (, ) Tj 0.522624 0 Td 43.552036 Tz (a ) Tj 1.602715 0 Td 43.552036 Tz (a ) Tj 0.470362 0 Td 51.778532 Tz (marker ) Tj 2.073077 0 Td 44.423077 Tz (associated ) Tj 2.874434 0 Td 47.90724 Tz (with ) Tj 1.376244 0 Td 67.747612 Tz (FHB ) Tj 1.358824 0 Td 20.324284 Tz (- ) Tj 0.191629 0 Td 41.229261 Tz (resistance ) Tj 2.700226 0 Td 42.100302 Tz (in ) Tj 0.731674 0 Td 42.826169 Tz (said ) Tj 1.219457 0 Td 46.455505 Tz (plant ) Tj 1.323982 0 Td 29.034691 Tz (; ) Tj 0.383258 0 Td 51.29462 Tz (and ) Tj 63.492063 0 0 63.492063 0 2624.008526 Tm 5.0715 0 Td 41.625 Tz (polynucleotide ) Tj 3.70125 0 Td 43.96875 Tz (sequence ) Tj 2.31525 0 Td 39.046875 Tz (selected ) Tj 2.03175 0 Td 47.25 Tz (from ) Tj 1.2915 0 Td 39.375 Tz (the ) Tj 0.89775 0 Td 44.625 Tz (group ) Tj 1.5435 0 Td 39.375 Tz (consisting ) Tj 3.591 0 Td 37.916667 Tz (selecting ) Tj 2.205 0 Td 39.375 Tz (a ) Tj 0.378 0 Td 61.25 Tz (FHB ) Tj 1.21275 0 Td 18.375 Tz (- ) Tj 0.17325 0 Td 35.291667 Tz (resistant ) Tj 2.03175 0 Td 39.375 Tz (plant ) Tj 1.323 0 Td 43.8375 Tz (comprising ) Tj 2.78775 0 Td 38.71875 Tz (said ) Tj 1.05525 0 Td 39.75 Tz (nucleic ) Tj 1.84275 0 Td 40.03125 Tz (acid ) Tj 1.008 0 Td 10.5 Tz (. ) Tj 61.648352 0 0 61.648352 0 2579.568379 Tm 5.239394 0 Td 45.959596 Tz (of ) Tj 0.827273 0 Td 60.378293 Tz (SEQ ) Tj 1.41123 0 Td 51.366607 Tz (ID ) Tj 0.924599 0 Td 71.6429 Tz (NO ) Tj 0.924599 0 Td 10.814023 Tz (: ) Tj 0.145989 0 Td 43.25609 Tz (2 ) Tj 0.3082 0 Td 13.517528 Tz (, ) Tj 0.437968 0 Td 43.25609 Tz (4 ) Tj 0.324421 0 Td 13.517528 Tz (, ) Tj 0.437968 0 Td 37.849079 Tz (5 ) Tj 0.583957 0 Td 41.904337 Tz (or ) Tj 0.827273 0 Td 31.090315 Tz (6. ) Tj 0.729947 0 Td 40.552585 Tz (In ) Tj 0.811052 0 Td 52.042484 Tz (some ) Tj 1.57344 0 Td 48.908875 Tz (embodiments ) Tj 3.536185 0 Td 41.453753 Tz (the ) Tj 1.995187 0 Td 40.552585 Tz (In ) Tj 0.63262 0 Td 39.007724 Tz (certain ) Tj 1.751872 0 Td 41.153364 Tz (preferred ) Tj 2.368271 0 Td 49.646195 Tz (embodiments ) Tj 3.211765 0 Td 24.331551 Tz (, ) Tj 0.3082 0 Td 40.552585 Tz (the ) Tj 0.875936 0 Td 63.081798 Tz (FHB ) Tj 1.200357 0 Td 24.331551 Tz (- ) Tj 0.210873 0 Td 40.061038 Tz (susceptible ) Tj 2.773797 0 Td 40.552585 Tz (plant ) Tj 56.785714 0 0 56.785714 0 2540.237942 Tm 5.68805 0 Td 42.557652 Tz (isolated ) Tj 2.254088 0 Td 44.444444 Tz (nucleic ) Tj 2.130818 0 Td 44.75891 Tz (acid ) Tj 1.320755 0 Td 49.475891 Tz (encodes ) Tj 2.342138 0 Td 44.025157 Tz (a ) Tj 0.510692 0 Td 45.492662 Tz (fusion ) Tj 1.849057 0 Td 43.186583 Tz (protein ) Tj 1.831447 0 Td 29.350105 Tz (. ) Tj 65.714286 0 0 65.714286 0 2537.074534 Tm 18.96087 0 Td 31.702899 Tz (10 ) Tj 0.776087 0 Td 27.898551 Tz (is ) Tj 0.563043 0 Td 37.726449 Tz (selected ) Tj 1.993478 0 Td 45.018116 Tz (from ) Tj 1.263043 0 Td 38.043478 Tz (the ) Tj 0.882609 0 Td 42.608696 Tz (group ) Tj 1.491304 0 Td 38.043478 Tz (consisting ) Tj 2.480435 0 Td 43.115942 Tz (of ) Tj 0.623913 0 Td 45.144928 Tz (wheat ) Tj 1.552174 0 Td 39.311594 Tz (or ) Tj 0.623913 0 Td 39.7343 Tz (barley ) Tj 1.369565 0 Td 25.362319 Tz (. ) Tj 0.35 0 Td 39.311594 Tz (In ) Tj 58.487395 0 0 58.487395 0 2498.966667 Tm 6.17227 0 Td 53.192848 Tz (The ) Tj 1.128448 0 Td 43.965517 Tz (present ) Tj 2.034626 0 Td 44.643997 Tz (invention ) Tj 2.581753 0 Td 40.60704 Tz (also ) Tj 1.179741 0 Td 45.237668 Tz (provides ) Tj 2.359483 0 Td 45.118934 Tz (polypeptides ) Tj 3.299856 0 Td 14.248084 Tz (, ) Tj 0.410345 0 Td 39.894636 Tz (includ- ) Tj 3.026293 0 Td 54.14272 Tz (some ) Tj 1.692672 0 Td 51.811216 Tz (embodiments ) Tj 3.402443 0 Td 25.646552 Tz (, ) Tj 0.530029 0 Td 42.744253 Tz (the ) Tj 1.145546 0 Td 40.963242 Tz (transfer ) Tj 2.325287 0 Td 47.018678 Tz (of ) Tj 0.871983 0 Td 43.151341 Tz (nucleic ) Tj 2.205603 0 Td 44.169061 Tz (acid ) Tj 1.419109 0 Td 41.522989 Tz (further ) Tj 61.031746 0 0 61.031746 0 2458.041611 Tm 5.292328 0 Td 41.872562 Tz (ing ) Tj 1.278023 0 Td 39.596879 Tz (isolated ) Tj 2.392198 0 Td 43.237971 Tz (polypeptides ) Tj 3.653836 0 Td 45.604681 Tz (comprising ) Tj 3.260598 0 Td 47.789337 Tz (an ) Tj 1.081404 0 Td 49.70091 Tz (amino ) Tj 2.03173 0 Td 42.327698 Tz (acid ) Tj 2.244733 0 Td 45.21023 Tz (comprises ) Tj 2.719896 0 Td 38.777633 Tz (steps ) Tj 1.425488 0 Td 49.154746 Tz (of ) Tj 0.491547 0 Td 19.115735 Tz (: ) Tj 0.409623 0 Td 41.986346 Tz (crossing ) Tj 2.277503 0 Td 40.279584 Tz (said ) Tj 1.196099 0 Td 61.89857 Tz (FHB ) Tj 1.261638 0 Td 21.846554 Tz (- ) Tj 0.196619 0 Td 36.410923 Tz (resistant ) Tj 2.179194 0 Td 40.962289 Tz (plant ) Tj 1.458257 0 Td 45.741222 Tz (with ) Tj 61.648352 0 0 61.648352 0 2415.108387 Tm 5.255615 0 Td 45.621658 Tz (sequence ) Tj 2.335829 0 Td 35.145573 Tz (at ) Tj 0.583957 0 Td 36.226976 Tz (least ) Tj 1.24902 0 Td 43.796791 Tz (about ) Tj 1.476114 0 Td 48.663102 Tz (70 ) Tj 0.600178 0 Td 78.401664 Tz (% ) Tj 0.648841 0 Td 37.849079 Tz (identical ) Tj 2.206061 0 Td 36.497326 Tz (to ) Tj 0.63262 0 Td 61.279461 Tz (SEQ ) Tj 1.265241 0 Td 51.366607 Tz (ID ) Tj 0.762389 0 Td 71.6429 Tz (NO ) Tj 0.924599 0 Td 10.814023 Tz (: ) Tj 0.129768 0 Td 40.552585 Tz (3 ) Tj 0.324421 0 Td 13.517528 Tz (, ) Tj 0.291979 0 Td 60.378293 Tz (SEQ ) Tj 2.335829 0 Td 48.663102 Tz (an ) Tj 0.811052 0 Td 59.477124 Tz (FHB ) Tj 1.24902 0 Td 27.035056 Tz (- ) Tj 0.227094 0 Td 39.077945 Tz (susceptible ) Tj 2.838681 0 Td 38.930481 Tz (plant ) Tj 1.427451 0 Td 37.849079 Tz (to ) Tj 0.713725 0 Td 46.345811 Tz (produce ) Tj 2.173619 0 Td 40.252195 Tz (offspring ) Tj 2.400713 0 Td 39.651416 Tz (plants ) Tj 1.492335 0 Td 16.221034 Tz (; ) Tj 0.356863 0 Td 48.663102 Tz (and ) Tj 58.916256 0 0 58.916256 0 2374.483822 Tm 5.482358 0 Td 53.748606 Tz (ID ) Tj 1.035368 0 Td 74.965162 Tz (NO ) Tj 0.967475 0 Td 11.315496 Tz (: ) Tj 0.135786 0 Td 45.261984 Tz (7 ) Tj 0.339465 0 Td 14.14437 Tz (, ) Tj 0.526171 0 Td 64.121145 Tz (SEQ ) Tj 1.561538 0 Td 52.334169 Tz (ID ) Tj 1.018395 0 Td 74.965162 Tz (NO ) Tj 0.967475 0 Td 11.315496 Tz (: ) Tj 0.152759 0 Td 42.43311 Tz (8 ) Tj 0.322492 0 Td 14.14437 Tz (, ) Tj 0.526171 0 Td 42.43311 Tz (or ) Tj 0.916555 0 Td 63.178187 Tz (SEQ ) Tj 1.544565 0 Td 53.748606 Tz (ID ) Tj 1.035368 0 Td 74.965162 Tz (NO ) Tj 0.967475 0 Td 11.315496 Tz (: ) Tj 0.152759 0 Td 42.43311 Tz (9 ) Tj 0.339465 0 Td 11.315496 Tz (. ) Tj 0.492224 0 Td 43.847547 Tz (In ) Tj 0.916555 0 Td 54.455825 Tz (some ) Tj 2.630853 0 Td 40.861514 Tz (selecting ) Tj 2.61388 0 Td 50.212514 Tz (from ) Tj 1.595485 0 Td 56.57748 Tz (among ) Tj 2.087709 0 Td 42.43311 Tz (the ) Tj 1.154181 0 Td 41.804472 Tz (offspring ) Tj 2.630853 0 Td 41.490152 Tz (plants ) Tj 1.901003 0 Td 42.43311 Tz (a ) Tj 0.644983 0 Td 41.867336 Tz (plant ) Tj 1.629431 0 Td 39.604236 Tz (that ) Tj 62.857143 0 0 62.857143 0 2331.157332 Tm 5.138636 0 Td 48.69146 Tz (embodiments ) Tj 3.197727 0 Td 23.863636 Tz (, ) Tj 0.334091 0 Td 39.772727 Tz (the ) Tj 0.922727 0 Td 48.257576 Tz (amino ) Tj 1.670455 0 Td 41.098485 Tz (acid ) Tj 1.193182 0 Td 44.744318 Tz (sequence ) Tj 2.354545 0 Td 45.075758 Tz (of ) Tj 0.684091 0 Td 39.772727 Tz (a ) Tj 0.429545 0 Td 42.424242 Tz (polypeptide ) Tj 3.006818 0 Td 45.075758 Tz (of ) Tj 0.890909 0 Td 31.818182 Tz (15 ) Tj 0.811364 0 Td 43.897306 Tz (comprises ) Tj 2.640909 0 Td 37.121212 Tz (in ) Tj 0.684091 0 Td 28.282828 Tz (its ) Tj 0.779545 0 Td 51.704545 Tz (genome ) Tj 2.1 0 Td 46.401515 Tz (an ) Tj 0.795455 0 Td 46.254209 Tz (exogenous ) Tj 2.768182 0 Td 47.064394 Tz (Fhbl ) Tj 1.415909 0 Td 40.530303 Tz (nucleic ) Tj 1.956818 0 Td 41.098485 Tz (acid ) Tj 1.034091 0 Td 10.606061 Tz (. ) Tj 58.857143 0 0 58.857143 0 2288.951266 Tm 5.470874 0 Td 42.475728 Tz (the ) Tj 0.934466 0 Td 44.363538 Tz (invention ) Tj 2.548544 0 Td 31.148867 Tz (is ) Tj 0.56068 0 Td 35.39644 Tz (at ) Tj 0.59466 0 Td 37.944984 Tz (least ) Tj 1.325243 0 Td 46.723301 Tz (95 ) Tj 0.61165 0 Td 82.119741 Tz (% ) Tj 0.679612 0 Td 39.644013 Tz (identical ) Tj 2.31068 0 Td 38.228155 Tz (to ) Tj 0.662621 0 Td 64.185545 Tz (SEQ ) Tj 1.325243 0 Td 53.802589 Tz (ID ) Tj 0.798544 0 Td 75.040453 Tz (NO ) Tj 0.968447 0 Td 11.326861 Tz (: ) Tj 0.135922 0 Td 42.475728 Tz (3 ) Tj 0.339806 0 Td 14.158576 Tz (, ) Tj 0.305825 0 Td 63.24164 Tz (SEQ ) Tj 2.480583 0 Td 51.678803 Tz (Such ) Tj 1.461165 0 Td 41.217188 Tz (selection ) Tj 2.429612 0 Td 49.083064 Tz (can ) Tj 1.087379 0 Td 47.785194 Tz (comprise ) Tj 2.497573 0 Td 51.914779 Tz (marker ) Tj 1.868932 0 Td 19.822006 Tz (- ) Tj 0.271845 0 Td 38.228155 Tz (assisted ) Tj 2.055825 0 Td 41.531823 Tz (selection ) Tj 2.429612 0 Td 47.43123 Tz (with ) Tj 58.482143 0 0 58.482143 0 2247.393733 Tm 5.523053 0 Td 54.147583 Tz (ID ) Tj 0.872061 0 Td 75.521628 Tz (NO ) Tj 0.974656 0 Td 11.399491 Tz (: ) Tj 0.136794 0 Td 45.597964 Tz (7 ) Tj 0.341985 0 Td 14.249364 Tz (, ) Tj 0.376183 0 Td 64.597116 Tz (SEQ ) Tj 1.402137 0 Td 54.147583 Tz (ID ) Tj 0.872061 0 Td 75.521628 Tz (NO ) Tj 0.974656 0 Td 11.399491 Tz (: ) Tj 0.170992 0 Td 42.748092 Tz (8 ) Tj 0.307786 0 Td 14.249364 Tz (, ) Tj 0.359084 0 Td 44.173028 Tz (or ) Tj 0.769466 0 Td 64.597116 Tz (SEQ ) Tj 1.402137 0 Td 52.722646 Tz (ID ) Tj 0.872061 0 Td 75.521628 Tz (NO ) Tj 0.974656 0 Td 11.399491 Tz (: ) Tj 0.153893 0 Td 42.748092 Tz (9 ) Tj 0.324885 0 Td 14.249364 Tz (, ) Tj 0.359084 0 Td 36.335878 Tz (e.g. ) Tj 0.940458 0 Td 14.249364 Tz (, ) Tj 0.359084 0 Td 48.447837 Tz (an ) Tj 0.820763 0 Td 51.867684 Tz (amino ) Tj 2.889771 0 Td 42.748092 Tz (a ) Tj 0.495878 0 Td 50.822731 Tz (marker ) Tj 2.069008 0 Td 43.603053 Tz (associated ) Tj 2.838473 0 Td 47.735369 Tz (with ) Tj 1.402137 0 Td 61.272265 Tz (FHB1 ) Tj 1.79542 0 Td 37.40458 Tz (activity ) Tj 1.846718 0 Td 28.498728 Tz (. ) Tj 0.427481 0 Td 42.748092 Tz (In ) Tj 0.786565 0 Td 54.147583 Tz (some ) Tj 1.57313 0 Td 59.847328 Tz (embodi ) Tj 59.142857 0 0 59.142857 0 2207.279357 Tm 5.461353 0 Td 43.679549 Tz (acid ) Tj 1.217391 0 Td 47.554348 Tz (sequence ) Tj 2.468599 0 Td 41.918277 Tz (selected ) Tj 2.181159 0 Td 50.020129 Tz (from ) Tj 1.352657 0 Td 42.270531 Tz (the ) Tj 0.94686 0 Td 47.342995 Tz (group ) Tj 1.623188 0 Td 42.270531 Tz (consisting ) Tj 2.705314 0 Td 47.906602 Tz (of ) Tj 0.693237 0 Td 63.87547 Tz (SEQ ) Tj 1.335749 0 Td 52.133655 Tz (ID ) Tj 1.927536 0 Td 50.161031 Tz (ments ) Tj 1.521739 0 Td 22.544283 Tz (, ) Tj 0.304348 0 Td 47.906602 Tz (an ) Tj 0.727053 0 Td 62.936125 Tz (FHB ) Tj 1.335749 0 Td 19.726248 Tz (- ) Tj 0.084541 0 Td 39.139381 Tz (resistant ) Tj 2.248792 0 Td 42.834138 Tz (plant ) Tj 1.217391 0 Td 28.180354 Tz (, ) Tj 0.355072 0 Td 43.679549 Tz (or ) Tj 0.65942 0 Td 42.270531 Tz (a ) Tj 0.405797 0 Td 40.861514 Tz (part ) Tj 1.115942 0 Td 43.478261 Tz (thereof ) Tj 1.775362 0 Td 25.362319 Tz (, ) Tj 0.304348 0 Td 49.31562 Tz (produced ) Tj 2.502415 0 Td 50.724638 Tz (by ) Tj 51.571429 0 0 51.571429 0 2166.848101 Tm 6.224377 0 Td 74.330563 Tz (NO ) Tj 1.066482 0 Td 29.085873 Tz (: ) Tj 0.290859 0 Td 29.085873 Tz (3 ) Tj 0.213296 0 Td 29.085873 Tz (, ) Tj 0.484765 0 Td 51.708218 Tz (7 ) Tj 0.387812 0 Td 16.158818 Tz (, ) Tj 0.426593 0 Td 48.476454 Tz (8 ) Tj 0.581717 0 Td 48.476454 Tz (or ) Tj 0.853186 0 Td 48.476454 Tz (9 ) Tj 0.387812 0 Td 12.927054 Tz (. ) Tj 61.428571 0 0 61.428571 0 2165.264368 Tm 21.113953 0 Td 40.697674 Tz (a ) Tj 0.423256 0 Td 51.098191 Tz (method ) Tj 2.018605 0 Td 44.767442 Tz (of ) Tj 0.651163 0 Td 40.697674 Tz (the ) Tj 0.927907 0 Td 42.50646 Tz (invention ) Tj 2.45814 0 Td 38.662791 Tz (will ) Tj 1.123256 0 Td 47.48062 Tz (have ) Tj 1.334884 0 Td 40.697674 Tz (a ) Tj 0.455814 0 Td 38.178295 Tz (susceptibility ) Tj 3.386047 0 Td 36.627907 Tz (to ) Tj 0.651163 0 Td 63.307494 Tz (FHB ) Tj 61.428571 0 0 61.428571 0 2121.223446 Tm 5.876744 0 Td 40.697674 Tz (In ) Tj 0.748837 0 Td 39.147287 Tz (certain ) Tj 1.904651 0 Td 41.300603 Tz (preferred ) Tj 2.506977 0 Td 49.330514 Tz (embodiments ) Tj 3.223256 0 Td 24.418605 Tz (, ) Tj 0.455814 0 Td 40.697674 Tz (a ) Tj 0.504651 0 Td 43.657505 Tz (polypeptide ) Tj 3.15814 0 Td 44.767442 Tz (of ) Tj 0.748837 0 Td 40.697674 Tz (the ) Tj 1.123256 0 Td 36.627907 Tz (20 ) Tj 0.846512 0 Td 37.984496 Tz (that ) Tj 1.090698 0 Td 29.844961 Tz (is ) Tj 0.569767 0 Td 33.914729 Tz (at ) Tj 0.602326 0 Td 36.356589 Tz (least ) Tj 1.269767 0 Td 40.697674 Tz (3 ) Tj 0.455814 0 Td 42.868217 Tz (times ) Tj 1.497674 0 Td 45.581395 Tz (lower ) Tj 1.530233 0 Td 43.410853 Tz (than ) Tj 1.22093 0 Td 40.697674 Tz (a ) Tj 0.439535 0 Td 40.451022 Tz (susceptible ) Tj 2.848837 0 Td 40.310078 Tz (control ) Tj 1.872093 0 Td 40.697674 Tz (plant ) Tj 61.176471 0 0 61.176471 0 2081.093711 Tm 5.263462 0 Td 42.681624 Tz (invention ) Tj 2.517308 0 Td 38.97929 Tz (substantially ) Tj 3.236538 0 Td 38.141026 Tz (retains ) Tj 1.814423 0 Td 40.865385 Tz (the ) Tj 0.948077 0 Td 41.137821 Tz (functional ) Tj 2.664423 0 Td 38.504274 Tz (characteristics ) Tj 4.756731 0 Td 46.314103 Tz (of ) Tj 0.719231 0 Td 40.865385 Tz (the ) Tj 1.013462 0 Td 50.400641 Tz (same ) Tj 1.4875 0 Td 40.865385 Tz (species ) Tj 1.781731 0 Td 13.621795 Tz (; ) Tj 0.359615 0 Td 47.092491 Tz (wherein ) Tj 2.190385 0 Td 40.865385 Tz (the ) Tj 0.980769 0 Td 44.497863 Tz (hybrid ) Tj 1.830769 0 Td 40.320513 Tz (plant ) Tj 1.471154 0 Td 41.546474 Tz (contains ) Tj 2.272115 0 Td 46.314103 Tz (an ) Tj 52.928571 0 0 52.928571 0 2043.43467 Tm 6.102564 0 Td 53.531264 Tz (of ) Tj 0.887989 0 Td 47.233468 Tz (a ) Tj 0.585695 0 Td 50.382366 Tz (polypeptide ) Tj 3.62753 0 Td 53.006448 Tz (having ) Tj 2.22942 0 Td 55.105713 Tz (an ) Tj 0.963563 0 Td 56.680162 Tz (amino ) Tj 2.059379 0 Td 48.020693 Tz (acid ) Tj 1.473684 0 Td 53.137652 Tz (sequence ) Tj 2.890688 0 Td 46.839856 Tz (selected ) Tj 3.684211 0 Td 55.892937 Tz (Fhbl ) Tj 1.605938 0 Td 48.133153 Tz (nucleic ) Tj 2.248313 0 Td 48.807917 Tz (acid ) Tj 1.360324 0 Td 55.630529 Tz (and ) Tj 1.190283 0 Td 53.981107 Tz (wherein ) Tj 2.493927 0 Td 45.659019 Tz (said ) Tj 1.303644 0 Td 55.892937 Tz (Fhbl ) Tj 1.605938 0 Td 48.133153 Tz (nucleic ) Tj 2.248313 0 Td 48.020693 Tz (acid ) Tj 1.360324 0 Td 34.637877 Tz (is ) Tj 0.623482 0 Td 50.382366 Tz (not ) Tj 60.645161 0 0 60.645161 0 1999.167209 Tm 5.326064 0 Td 49.468085 Tz (from ) Tj 1.368617 0 Td 41.223404 Tz (the ) Tj 0.956383 0 Td 46.719858 Tz (group ) Tj 1.632447 0 Td 41.223404 Tz (consisting ) Tj 2.687766 0 Td 46.719858 Tz (of ) Tj 0.725532 0 Td 62.293144 Tz (SEQ ) Tj 1.335638 0 Td 52.216312 Tz (ID ) Tj 0.824468 0 Td 72.828014 Tz (NO ) Tj 0.939894 0 Td 10.992908 Tz (: ) Tj 0.131915 0 Td 41.223404 Tz (3 ) Tj 0.329787 0 Td 13.741135 Tz (, ) Tj 0.329787 0 Td 43.971631 Tz (7 ) Tj 0.329787 0 Td 13.741135 Tz (, ) Tj 0.346277 0 Td 41.223404 Tz (8 ) Tj 0.478191 0 Td 41.223404 Tz (or ) Tj 0.709043 0 Td 41.223404 Tz (9 ) Tj 0.313298 0 Td 13.741135 Tz (, ) Tj 0.329787 0 Td 34.352837 Tz (e.g. ) Tj 0.906915 0 Td 13.741135 Tz (, ) Tj 1.385106 0 Td 38.475177 Tz (in ) Tj 0.593617 0 Td 41.223404 Tz (the ) Tj 0.890426 0 Td 40.045593 Tz (natural ) Tj 1.863298 0 Td 41.223404 Tz (genetic ) Tj 1.896277 0 Td 48.643617 Tz (background ) Tj 3.050532 0 Td 46.719858 Tz (of ) Tj 0.626596 0 Td 42.13948 Tz (the ) Tj 0.906915 0 Td 62.293144 Tz (FHB ) Tj 1.30266 0 Td 19.237589 Tz (- ) Tj 0.082447 0 Td 38.169819 Tz (resistant ) Tj 2.193085 0 Td 43.971631 Tz (plant ) Tj 1.236702 0 Td 27.48227 Tz (. ) Tj 63.458647 0 0 63.458647 0 1958.013004 Tm 5.074171 0 Td 40.271195 Tz (the ) Tj 1.008531 0 Td 42.022117 Tz (polypeptide ) Tj 3.057109 0 Td 42.022117 Tz (has ) Tj 1.071564 0 Td 56.46722 Tz (FHB1 ) Tj 1.701896 0 Td 36.441055 Tz (activity ) Tj 1.717654 0 Td 26.263823 Tz (. ) Tj 0.456991 0 Td 39.395735 Tz (In ) Tj 0.756398 0 Td 39.103914 Tz (preferred ) Tj 2.58436 0 Td 43.522907 Tz (embodi- ) Tj 3.592891 0 Td 49.901264 Tz (The ) Tj 1.103081 0 Td 41.146656 Tz (invention ) Tj 2.411019 0 Td 37.894945 Tz (further ) Tj 1.764929 0 Td 41.693819 Tz (provides ) Tj 2.221919 0 Td 61.282254 Tz (FHB ) Tj 1.244905 0 Td 18.384676 Tz (- ) Tj 0.078791 0 Td 36.185712 Tz (resistant ) Tj 2.143128 0 Td 39.833465 Tz (plants ) Tj 1.38673 0 Td 26.263823 Tz (, ) Tj 0.362441 0 Td 46.399421 Tz (and ) Tj 60 0 0 60 0 1916.326595 Tm 5.366667 0 Td 48.888889 Tz (ments ) Tj 1.7 0 Td 41.666667 Tz (the ) Tj 0.966667 0 Td 44.444444 Tz (polypeptide ) Tj 3.133333 0 Td 45.37037 Tz (has ) Tj 1.05 0 Td 41.666667 Tz (antifungal ) Tj 2.733333 0 Td 38.888889 Tz (activity ) Tj 1.783333 0 Td 27.777778 Tz (, ) Tj 0.433333 0 Td 46.527778 Tz (such ) Tj 1.316667 0 Td 40.277778 Tz (as ) Tj 0.733333 0 Td 36.666667 Tz (anti- ) Tj 1.516667 0 Td 36.111111 Tz (25 ) Tj 0.866667 0 Td 39.444444 Tz (parts ) Tj 1.466667 0 Td 42.460317 Tz (thereof ) Tj 1.733333 0 Td 25 Tz (, ) Tj 0.433333 0 Td 38.888889 Tz (that ) Tj 1.216667 0 Td 46.875 Tz (comprise ) Tj 2.516667 0 Td 44.444444 Tz (within ) Tj 1.85 0 Td 38.333333 Tz (their ) Tj 1.416667 0 Td 54.166667 Tz (genome ) Tj 2.233333 0 Td 47.222222 Tz (an ) Tj 0.833333 0 Td 49.305556 Tz (Fhbl ) Tj 56.8 0 0 56.8 0 1875.857051 Tm 5.68662 0 Td 45.481221 Tz (fungal ) Tj 1.830986 0 Td 40.346244 Tz (activity ) Tj 2.09507 0 Td 49.044266 Tz (towards ) Tj 2.253521 0 Td 44.014085 Tz (a ) Tj 0.457746 0 Td 43.594903 Tz (species ) Tj 2.024648 0 Td 48.415493 Tz (of ) Tj 0.651408 0 Td 48.782277 Tz (Fusarium ) Tj 2.588028 0 Td 26.408451 Tz (, ) Tj 0.316901 0 Td 37.411972 Tz (e.g. ) Tj 0.96831 0 Td 14.671362 Tz (, ) Tj 0.299296 0 Td 44.014085 Tz (a ) Tj 0.440141 0 Td 44.014085 Tz (species ) Tj 3.204225 0 Td 44.433266 Tz (nucleic ) Tj 2.09507 0 Td 44.747653 Tz (acid ) Tj 1.109155 0 Td 14.671362 Tz (, ) Tj 0.299296 0 Td 50.720993 Tz (wherein ) Tj 2.323944 0 Td 43.280516 Tz (said ) Tj 1.232394 0 Td 49.882629 Tz (an ) Tj 0.792254 0 Td 52.083333 Tz (Fhb1 ) Tj 1.496479 0 Td 44.852448 Tz (nucleic ) Tj 2.09507 0 Td 45.481221 Tz (acid ) Tj 1.267606 0 Td 33.744131 Tz (is ) Tj 0.598592 0 Td 45.970266 Tz (not ) Tj 1.021127 0 Td 42.546948 Tz (in ) Tj 0.669014 0 Td 44.014085 Tz (the ) Tj 59.254658 0 0 59.254658 0 1832.889105 Tm 5.467925 0 Td 41.839186 Tz (selected ) Tj 2.227673 0 Td 50.628931 Tz (from ) Tj 1.400734 0 Td 36.565339 Tz (F. ) Tj 0.708805 0 Td 49.066309 Tz (avenaceum ) Tj 2.852096 0 Td 16.87631 Tz (, ) Tj 0.32065 0 Td 36.565339 Tz (F. ) Tj 0.708805 0 Td 47.816212 Tz (bubigeum ) Tj 2.430189 0 Td 28.127184 Tz (, ) Tj 0.388155 0 Td 36.565339 Tz (F. ) Tj 0.708805 0 Td 49.925751 Tz (culmorum ) Tj 2.51457 0 Td 25.314465 Tz (, ) Tj 0.388155 0 Td 37.971698 Tz (F. ) Tj 1.755136 0 Td 40.985325 Tz (natural ) Tj 1.991405 0 Td 42.592593 Tz (genetic ) Tj 2.025157 0 Td 49.785115 Tz (background ) Tj 3.223375 0 Td 47.816212 Tz (of ) Tj 0.77631 0 Td 40.784416 Tz (said ) Tj 1.215094 0 Td 62.817377 Tz (FHB ) Tj 1.350105 0 Td 19.689029 Tz (- ) Tj 0.168763 0 Td 37.190387 Tz (resistant ) Tj 2.244549 0 Td 42.753319 Tz (plant ) Tj 1.215094 0 Td 28.127184 Tz (. ) Tj 0.438784 0 Td 42.190776 Tz (In ) Tj 63.061224 0 0 63.061224 0 1790.857518 Tm 5.169579 0 Td 45.890948 Tz (graminearum ) Tj 3.234951 0 Td 34.358145 Tz (, ) Tj 0.380583 0 Td 34.358145 Tz (F. ) Tj 0.777023 0 Td 41.806414 Tz (langsethiae ) Tj 2.695793 0 Td 26.429342 Tz (, ) Tj 0.475728 0 Td 34.358145 Tz (F. ) Tj 0.777023 0 Td 43.755244 Tz (oxysporum ) Tj 2.568932 0 Td 18.500539 Tz (, ) Tj 0.459871 0 Td 34.358145 Tz (F. ) Tj 0.697735 0 Td 50.21575 Tz (poae ) Tj 1.221036 0 Td 13.214671 Tz (, ) Tj 0.444013 0 Td 35.679612 Tz (F. ) Tj 1.680906 0 Td 50.21575 Tz (some ) Tj 1.443042 0 Td 47.332549 Tz (embodiments ) Tj 3.203236 0 Td 23.786408 Tz (, ) Tj 0.33301 0 Td 40.524991 Tz (the ) Tj 0.951456 0 Td 41.405969 Tz (invention ) Tj 2.442071 0 Td 41.95658 Tz (provides ) Tj 2.267638 0 Td 39.644013 Tz (a ) Tj 0.459871 0 Td 43.167925 Tz (hybrid ) Tj 1.807767 0 Td 74.002157 Tz (FHB ) Tj 63.537415 0 0 63.537415 0 1748.560133 Tm 5.06788 0 Td 40.002677 Tz (sporotrichioides ) Tj 3.808779 0 Td 26.231263 Tz (, ) Tj 0.50364 0 Td 36.723769 Tz (F. ) Tj 0.802677 0 Td 36.986081 Tz (tricinctum ) Tj 2.40803 0 Td 20.985011 Tz (, ) Tj 0.472163 0 Td 34.100642 Tz (F. ) Tj 0.802677 0 Td 36.374019 Tz (verticillioides ) Tj 3.194968 0 Td 23.608137 Tz (, ) Tj 0.535118 0 Td 46.341899 Tz (and ) Tj 1.164668 0 Td 34.100642 Tz (F. ) Tj 1.636831 0 Td 36.140852 Tz (resistant ) Tj 2.250642 0 Td 41.445396 Tz (plant ) Tj 1.133191 0 Td 26.231263 Tz (, ) Tj 0.50364 0 Td 40.658458 Tz (or ) Tj 0.771199 0 Td 37.37955 Tz (part ) Tj 1.196146 0 Td 40.845824 Tz (thereof ) Tj 1.684047 0 Td 23.608137 Tz (, ) Tj 0.424946 0 Td 45.904711 Tz (produced ) Tj 2.486724 0 Td 47.216274 Tz (by ) Tj 0.897109 0 Td 40.330567 Tz (crossing ) Tj 2.250642 0 Td 44.593148 Tz (an ) Tj 65.714286 0 0 65.714286 0 1707.177861 Tm 4.915217 0 Td 39.522947 Tz (virguliforme ) Tj 2.8 0 Td 25.362319 Tz (. ) Tj 0.41087 0 Td 39.311594 Tz (In ) Tj 0.730435 0 Td 48.822464 Tz (some ) Tj 1.430435 0 Td 46.343874 Tz (embodiments ) Tj 3.043478 0 Td 22.826087 Tz (, ) Tj 0.41087 0 Td 38.043478 Tz (a ) Tj 0.486957 0 Td 40.57971 Tz (polypeptide ) Tj 2.936957 0 Td 43.115942 Tz (of ) Tj 0.715217 0 Td 38.043478 Tz (the ) Tj 1.05 0 Td 34.23913 Tz (30 ) Tj 0.806522 0 Td 57.487923 Tz (FHB ) Tj 1.186957 0 Td 17.753623 Tz (- ) Tj 0.167391 0 Td 33.534622 Tz (resistant ) Tj 1.993478 0 Td 37.536232 Tz (plant ) Tj 1.308696 0 Td 43.115942 Tz (of ) Tj 0.623913 0 Td 38.043478 Tz (the ) Tj 0.867391 0 Td 39.7343 Tz (invention ) Tj 2.297826 0 Td 42.481884 Tz (with ) Tj 1.202174 0 Td 40.217391 Tz (another ) Tj 1.856522 0 Td 37.536232 Tz (plant ) Tj 1.293478 0 Td 35.507246 Tz (that ) Tj 56.904762 0 0 56.904762 0 1667.172775 Tm 5.676151 0 Td 45.885635 Tz (invention ) Tj 2.706276 0 Td 32.217573 Tz (is ) Tj 0.650209 0 Td 43.933054 Tz (a ) Tj 0.509623 0 Td 45.39749 Tz (fusion ) Tj 1.845188 0 Td 44.769874 Tz (protein ) Tj 1.915481 0 Td 11.715481 Tz (. ) Tj 60 0 0 60 0 1667.180523 Tm 21.616667 0 Td 40.277778 Tz (exhibits ) Tj 2.133333 0 Td 47.222222 Tz (commercially ) Tj 3.6 0 Td 41.049383 Tz (desirable ) Tj 2.416667 0 Td 39.62963 Tz (characteristics ) Tj 3.516667 0 Td 25 Tz (, ) Tj 0.35 0 Td 48.015873 Tz (wherein ) Tj 2.183333 0 Td 41.666667 Tz (the ) Tj 59.52381 0 0 59.52381 0 1625.249211 Tm 6.0648 0 Td 52.266667 Tz (The ) Tj 1.1088 0 Td 43.2 Tz (present ) Tj 1.9992 0 Td 43.555556 Tz (invention ) Tj 2.52 0 Td 44.45 Tz (provides ) Tj 2.3184 0 Td 50 Tz (methods ) Tj 2.3184 0 Td 40.133333 Tz (for ) Tj 0.8736 0 Td 46.977778 Tz (producing ) Tj 2.7216 0 Td 49 Tz (an ) Tj 1.8312 0 Td 45.733333 Tz (hybrid ) Tj 1.7976 0 Td 41.44 Tz (plant ) Tj 1.428 0 Td 42.7 Tz (contains ) Tj 2.2512 0 Td 49 Tz (an ) Tj 0.756 0 Td 49.7 Tz (Fhbl ) Tj 1.428 0 Td 42.4 Tz (nucleic ) Tj 1.9824 0 Td 43.4 Tz (acid ) Tj 1.2096 0 Td 49.466667 Tz (and ) Tj 1.0416 0 Td 48.4 Tz (wherein ) Tj 2.2176 0 Td 40.6 Tz (said ) Tj 58.944099 0 0 58.944099 0 1583.364038 Tm 5.496733 0 Td 59.378293 Tz (FHB ) Tj 1.289357 0 Td 19.792764 Tz (- ) Tj 0.169652 0 Td 38.328845 Tz (resistant ) Tj 2.307271 0 Td 41.847559 Tz (plant ) Tj 1.49294 0 Td 38.17176 Tz (that ) Tj 1.187566 0 Td 47.753971 Tz (comprises ) Tj 2.510854 0 Td 28.275378 Tz (: ) Tj 0.475026 0 Td 22.620302 Tz (\( ) Tj 0.203583 0 Td 39.585529 Tz (a ) Tj 0.305374 0 Td 22.620302 Tz (\) ) Tj 0.407165 0 Td 46.937127 Tz (performing ) Tj 3.053741 0 Td 49.953167 Tz (marker ) Tj 3.104636 0 Td 50.188795 Tz (Fhbl ) Tj 1.425079 0 Td 43.220934 Tz (nucleic ) Tj 2.001897 0 Td 43.119951 Tz (acid ) Tj 1.187566 0 Td 32.516684 Tz (is ) Tj 0.559852 0 Td 44.298092 Tz (not ) Tj 0.967018 0 Td 39.585529 Tz (in ) Tj 0.610748 0 Td 42.413066 Tz (the ) Tj 0.916122 0 Td 41.605198 Tz (natural ) Tj 1.934036 0 Td 42.413066 Tz (genetic ) Tj 1.951001 0 Td 50.047418 Tz (background ) Tj 3.155532 0 Td 48.068142 Tz (of ) Tj 59.52381 0 0 59.52381 0 1540.839965 Tm 5.4264 0 Td 40.6 Tz (assisted ) Tj 2.1504 0 Td 41.066667 Tz (selection ) Tj 2.3856 0 Td 39.2 Tz (to ) Tj 0.7056 0 Td 39.9 Tz (identify ) Tj 2.1336 0 Td 42 Tz (a ) Tj 0.4368 0 Td 42 Tz (plant ) Tj 1.4448 0 Td 44.8 Tz (possessing ) Tj 2.8896 0 Td 42 Tz (a ) Tj 0.4536 0 Td 41.16 Tz (resistance ) Tj 3.7464 0 Td 42 Tz (the ) Tj 0.9912 0 Td 63.466667 Tz (FHB ) Tj 1.3104 0 Td 22.4 Tz (- ) Tj 0.1512 0 Td 37.955556 Tz (resistant ) Tj 2.268 0 Td 42.56 Tz (plant ) Tj 1.2096 0 Td 28 Tz (. ) Tj 60.559006 0 0 60.559006 0 1501.116172 Tm 5.333641 0 Td 36.695157 Tz (allele ) Tj 1.568718 0 Td 46.786325 Tz (of ) Tj 0.743077 0 Td 53.666667 Tz (Fhbl ) Tj 1.238462 0 Td 24.769231 Tz (; ) Tj 0.429333 0 Td 48.621083 Tz (and ) Tj 1.139385 0 Td 30.273504 Tz (\( ) Tj 0.280718 0 Td 27.521368 Tz (b ) Tj 0.214667 0 Td 27.521368 Tz (\) ) Tj 0.429333 0 Td 42.933333 Tz (generating ) Tj 2.840205 0 Td 41.282051 Tz (a ) Tj 0.478872 0 Td 47.965812 Tz (progeny ) Tj 2.262256 0 Td 46.786325 Tz (of ) Tj 0.75959 0 Td 40.594017 Tz (said ) Tj 1.188923 0 Td 41.282051 Tz (plant ) Tj 1.634769 0 Td 35.777778 Tz (35 ) Tj 1.486154 0 Td 52.290598 Tz (The ) Tj 1.205436 0 Td 42.068376 Tz (present ) Tj 2.04759 0 Td 43.116809 Tz (invention ) Tj 2.592513 0 Td 39.217949 Tz (also ) Tj 1.221949 0 Td 43.690171 Tz (provides ) Tj 2.410872 0 Td 42.933333 Tz (seeds ) Tj 1.552205 0 Td 48.162393 Tz (produced ) Tj 2.559487 0 Td 49.538462 Tz (by ) Tj 61.804511 0 0 61.804511 0 1457.858247 Tm 5.209976 0 Td 46.61395 Tz (wherein ) Tj 2.281387 0 Td 39.775953 Tz (said ) Tj 1.245864 0 Td 46.999189 Tz (progeny ) Tj 2.297567 0 Td 42.547535 Tz (possesses ) Tj 2.653528 0 Td 39.775953 Tz (said ) Tj 1.245864 0 Td 39.641119 Tz (resistance ) Tj 2.702068 0 Td 35.955664 Tz (allele ) Tj 1.618005 0 Td 45.843471 Tz (of ) Tj 1.715085 0 Td 47.384428 Tz (growing ) Tj 2.184307 0 Td 40.450122 Tz (a ) Tj 0.436861 0 Td 39.910787 Tz (plant ) Tj 1.391484 0 Td 45.843471 Tz (of ) Tj 0.679562 0 Td 39.55123 Tz (the ) Tj 0.922263 0 Td 40.450122 Tz (invention ) Tj 2.232847 0 Td 24.270073 Tz (, ) Tj 0.355961 0 Td 46.61395 Tz (wherein ) Tj 2.135766 0 Td 40.450122 Tz (the ) Tj 0.938443 0 Td 43.820965 Tz (seed ) Tj 1.229684 0 Td 41.461375 Tz (contains ) Tj 55.714286 0 0 55.714286 0 1415.61559 Tm 5.797436 0 Td 53.098291 Tz (Fhbl ) Tj 1.669231 0 Td 43.376068 Tz (exhibits ) Tj 2.405128 0 Td 38.888889 Tz (at ) Tj 0.771795 0 Td 40.08547 Tz (least ) Tj 1.507692 0 Td 40.17094 Tz (partial ) Tj 1.992308 0 Td 43.974359 Tz (resistance ) Tj 2.925641 0 Td 41.880342 Tz (to ) Tj 0.825641 0 Td 69.80057 Tz (FHB ) Tj 1.346154 0 Td 11.965812 Tz (. ) Tj 0.412821 0 Td 46.367521 Tz (In ) Tj 0.861538 0 Td 57.58547 Tz (some ) Tj 2.764103 0 Td 52.350427 Tz (an ) Tj 0.825641 0 Td 53.098291 Tz (Fhbl ) Tj 1.561538 0 Td 45.299145 Tz (nucleic ) Tj 2.153846 0 Td 45.619658 Tz (acid ) Tj 1.310256 0 Td 52.849003 Tz (and ) Tj 1.148718 0 Td 51.709402 Tz (wherein ) Tj 2.387179 0 Td 44.123932 Tz (said ) Tj 1.25641 0 Td 53.846154 Tz (Fhb1 ) Tj 1.561538 0 Td 45.726496 Tz (nucleic ) Tj 2.153846 0 Td 46.367521 Tz (acid ) Tj 1.310256 0 Td 34.401709 Tz (is ) Tj 58.639456 0 0 58.639456 0 1374.792644 Tm 5.508237 0 Td 51.676861 Tz (embodiments ) Tj 3.393619 0 Td 25.580046 Tz (, ) Tj 0.426334 0 Td 42.633411 Tz (the ) Tj 1.023202 0 Td 53.528616 Tz (method ) Tj 2.148724 0 Td 47.607309 Tz (produces ) Tj 2.558005 0 Td 49.738979 Tz (an ) Tj 0.852668 0 Td 63.476411 Tz (FHB ) Tj 1.330162 0 Td 19.895592 Tz (- ) Tj 0.15348 0 Td 38.212168 Tz (resistant ) Tj 2.336311 0 Td 35.812065 Tz (elite ) Tj 2.370418 0 Td 44.528229 Tz (not ) Tj 1.040255 0 Td 41.212297 Tz (in ) Tj 0.699188 0 Td 42.633411 Tz (the ) Tj 0.989095 0 Td 41.821346 Tz (natural ) Tj 2.012297 0 Td 42.633411 Tz (genetic ) Tj 2.02935 0 Td 50.307425 Tz (background ) Tj 3.240139 0 Td 48.317865 Tz (of ) Tj 0.733295 0 Td 42.633411 Tz (the ) Tj 1.006148 0 Td 64.423821 Tz (FHB ) Tj 1.296056 0 Td 19.895592 Tz (- ) Tj 0.170534 0 Td 38.843774 Tz (resistant ) Tj 57.07483 0 0 57.07483 0 1334.227097 Tm 5.624195 0 Td 44.970203 Tz (plant ) Tj 1.261502 0 Td 29.20143 Tz (. ) Tj 0.508105 0 Td 45.262217 Tz (In ) Tj 0.858522 0 Td 55.482718 Tz (some ) Tj 1.646961 0 Td 53.358977 Tz (embodiments ) Tj 3.46913 0 Td 26.281287 Tz (, ) Tj 0.490584 0 Td 51.589193 Tz (marker ) Tj 2.155066 0 Td 41.977056 Tz (assisted ) Tj 2.330274 0 Td 42.828764 Tz (selection ) Tj 2.593087 0 Td 33.581645 Tz (is ) Tj 1.769607 0 Td 47.306317 Tz (plant ) Tj 1.261502 0 Td 29.20143 Tz (. ) Tj 0.543147 0 Td 45.262217 Tz (In ) Tj 0.841001 0 Td 44.775526 Tz (preferred ) Tj 2.733254 0 Td 53.358977 Tz (embodiments ) Tj 3.504172 0 Td 26.281287 Tz (, ) Tj 0.525626 0 Td 45.554231 Tz (seeds ) Tj 1.41919 0 Td 14.600715 Tz (, ) Tj 0.455542 0 Td 42.828764 Tz (plants ) Tj 1.892253 0 Td 52.562574 Tz (and ) Tj 1.243981 0 Td 43.802145 Tz (plant ) Tj 61.428571 0 0 61.428571 0 1289.959121 Tm 5.25814 0 Td 46.124031 Tz (conducted ) Tj 2.62093 0 Td 43.953488 Tz (using ) Tj 1.481395 0 Td 47.48062 Tz (an ) Tj 0.716279 0 Td 42.868217 Tz (assay ) Tj 1.481395 0 Td 40.358527 Tz (selected ) Tj 2.083721 0 Td 48.837209 Tz (from ) Tj 1.302326 0 Td 40.697674 Tz (the ) Tj 0.911628 0 Td 45.581395 Tz (group ) Tj 1.546512 0 Td 40.968992 Tz (consisting ) Tj 2.832558 0 Td 37.984496 Tz (40 ) Tj 0.862791 0 Td 38.527132 Tz (parts ) Tj 1.351163 0 Td 45.445736 Tz (provided ) Tj 2.344186 0 Td 50.193798 Tz (by ) Tj 0.781395 0 Td 40.697674 Tz (the ) Tj 0.944186 0 Td 42.204996 Tz (invention ) Tj 2.474419 0 Td 39.793282 Tz (are ) Tj 0.927907 0 Td 40.358527 Tz (selected ) Tj 2.116279 0 Td 48.837209 Tz (from ) Tj 1.334884 0 Td 41.602067 Tz (the ) Tj 0.944186 0 Td 45.581395 Tz (group ) Tj 63.834586 0 0 63.834586 0 1249.281781 Tm 5.059953 0 Td 44.385552 Tz (of ) Tj 0.642285 0 Td 37.858265 Tz (single ) Tj 1.519552 0 Td 43.080094 Tz (base ) Tj 1.190577 0 Td 41.484535 Tz (extension ) Tj 2.412485 0 Td 26.109148 Tz (\( ) Tj 0.187986 0 Td 57.440126 Tz (SBE ) Tj 1.065253 0 Td 26.109148 Tz (\) ) Tj 0.219317 0 Td 13.054574 Tz (, ) Tj 0.266313 0 Td 34.812197 Tz (allele ) Tj 1.315901 0 Td 26.109148 Tz (- ) Tj 0.203651 0 Td 35.24735 Tz (specific ) Tj 1.864193 0 Td 43.515247 Tz (primer ) Tj 1.801531 0 Td 38.72857 Tz (exten- ) Tj 2.553475 0 Td 39.685905 Tz (consisting ) Tj 2.56914 0 Td 46.996466 Tz (of ) Tj 0.689282 0 Td 46.474283 Tz (wheat ) Tj 1.59788 0 Td 45.255857 Tz (and ) Tj 1.033922 0 Td 38.293417 Tz (barley ) Tj 1.425559 0 Td 26.109148 Tz (. ) Tj 59.172932 0 0 59.172932 0 1209.829472 Tm 5.475476 0 Td 42.249047 Tz (sion ) Tj 1.250572 0 Td 47.318933 Tz (sequencing ) Tj 3.075731 0 Td 22.532825 Tz (\( ) Tj 0.202795 0 Td 61.965269 Tz (ASPE ) Tj 1.554765 0 Td 28.166031 Tz (\) ) Tj 0.202795 0 Td 16.899619 Tz (, ) Tj 0.371792 0 Td 73.231681 Tz (DNA ) Tj 1.554765 0 Td 46.755612 Tz (sequencing ) Tj 2.839136 0 Td 16.899619 Tz (, ) Tj 0.371792 0 Td 71.353946 Tz (RNA ) Tj 1.504066 0 Td 46.826027 Tz (sequenc- ) Tj 4.123507 0 Td 53.51546 Tz (The ) Tj 1.199873 0 Td 43.456163 Tz (present ) Tj 2.078653 0 Td 44.126782 Tz (invention ) Tj 2.619441 0 Td 40.840745 Tz (also ) Tj 1.233672 0 Td 44.713575 Tz (provides ) Tj 2.416645 0 Td 50.296485 Tz (methods ) Tj 2.382846 0 Td 40.371312 Tz (for ) Tj 1.013977 0 Td 45.06565 Tz (identi ) Tj 63.376623 0 0 63.376623 0 1167.108962 Tm 5.096516 0 Td 40.323315 Tz (ing ) Tj 0.773156 0 Td 13.148907 Tz (, ) Tj 0.331352 0 Td 42.339481 Tz (microarray ) Tj 2.635041 0 Td 26.297814 Tz (- ) Tj 0.142008 0 Td 45.23224 Tz (based ) Tj 1.593648 0 Td 40.432889 Tz (analyses ) Tj 1.925 0 Td 26.297814 Tz (, ) Tj 0.410246 0 Td 39.738919 Tz (universal ) Tj 2.398361 0 Td 61.361566 Tz (PCR ) Tj 1.136066 0 Td 13.148907 Tz (, ) Tj 0.347131 0 Td 35.063752 Tz (allele ) Tj 1.514754 0 Td 40.104167 Tz (spe- ) Tj 2.16168 0 Td 40.498634 Tz (fying ) Tj 1.467418 0 Td 39.446721 Tz (a ) Tj 0.473361 0 Td 39.446721 Tz (plant ) Tj 1.404303 0 Td 36.81694 Tz (that ) Tj 1.136066 0 Td 43.537492 Tz (comprises ) Tj 2.619262 0 Td 39.446721 Tz (a ) Tj 0.489139 0 Td 44.706284 Tz (genotype ) Tj 2.382582 0 Td 40.498634 Tz (associated ) Tj 2.65082 0 Td 43.391393 Tz (with ) Tj 1.278074 0 Td 39.446721 Tz (a ) Tj 62.012987 0 0 62.012987 0 1125.901064 Tm 5.208586 0 Td 33.326353 Tz (cific ) Tj 1.273927 0 Td 42.703122 Tz (extension ) Tj 2.289843 0 Td 24.188482 Tz (, ) Tj 0.387016 0 Td 41.141093 Tz (hybridization ) Tj 3.19288 0 Td 26.876091 Tz (, ) Tj 0.403141 0 Td 49.048866 Tz (mass ) Tj 1.467435 0 Td 42.329843 Tz (spectrometry ) Tj 3.047749 0 Td 24.188482 Tz (, ) Tj 0.435393 0 Td 36.282723 Tz (ligation ) Tj 1.822199 0 Td 26.876091 Tz (, ) Tj 1.402932 0 Td 59.1274 Tz (FHB ) Tj 1.22555 0 Td 21.500873 Tz (- ) Tj 0.209634 0 Td 38.164049 Tz (resistance ) Tj 2.273717 0 Td 21.500873 Tz (, ) Tj 0.354764 0 Td 43.808028 Tz (comprising ) Tj 2.676859 0 Td 26.876091 Tz (: ) Tj 0.387016 0 Td 40.612759 Tz (detecting ) Tj 2.418848 0 Td 34.938918 Tz (in ) Tj 0.645026 0 Td 38.970332 Tz (said ) Tj 1.128796 0 Td 39.776614 Tz (plant ) Tj 1.386806 0 Td 37.626527 Tz (a ) Tj 0.451518 0 Td 71.669575 Tz (DNA ) Tj 62.857143 0 0 62.857143 0 1082.719221 Tm 5.138636 0 Td 40.951178 Tz (extension ) Tj 2.306818 0 Td 26.515152 Tz (- ) Tj 0.238636 0 Td 35.464015 Tz (ligation ) Tj 1.702273 0 Td 26.515152 Tz (, ) Tj 0.35 0 Td 46.843434 Tz (and ) Tj 1.002273 0 Td 41.761364 Tz (Flap ) Tj 1.193182 0 Td 44.854798 Tz (Endonuclease ) Tj 3.388636 0 Td 18.560606 Tz (- ) Tj 0.047727 0 Td 46.732955 Tz (mediated ) Tj 2.386364 0 Td 41.098485 Tz (assays ) Tj 1.559091 0 Td 10.606061 Tz (. ) Tj 0.461364 0 Td 35.795455 Tz (45 ) Tj 0.843182 0 Td 48.169192 Tz (polymorphism ) Tj 3.834091 0 Td 38.44697 Tz (in ) Tj 0.811364 0 Td 46.401515 Tz (an ) Tj 0.922727 0 Td 47.064394 Tz (Fhbl ) Tj 1.575 0 Td 40.30303 Tz (locus ) Tj 1.606818 0 Td 40.568182 Tz (associated ) Tj 2.768182 0 Td 44.412879 Tz (with ) Tj 1.431818 0 Td 76.010101 Tz (FHB ) Tj 59.285714 0 0 59.285714 0 1042.448735 Tm 5.448193 0 Td 43.574297 Tz (In ) Tj 0.826506 0 Td 54.116466 Tz (some ) Tj 1.60241 0 Td 50.346842 Tz (embodiments ) Tj 3.390361 0 Td 25.301205 Tz (, ) Tj 0.455422 0 Td 42.168675 Tz (a ) Tj 0.556627 0 Td 41.606426 Tz (plant ) Tj 1.551807 0 Td 48.845382 Tz (produced ) Tj 2.631325 0 Td 45.542169 Tz (using ) Tj 1.66988 0 Td 42.168675 Tz (a ) Tj 0.556627 0 Td 52.945114 Tz (method ) Tj 3.171084 0 Td 41.044177 Tz (resistance ) Tj 2.479518 0 Td 25.301205 Tz (, ) Tj 0.472289 0 Td 49.665328 Tz (and ) Tj 1.231325 0 Td 40.606872 Tz (selecting ) Tj 2.53012 0 Td 40.763052 Tz (said ) Tj 1.26506 0 Td 42.168675 Tz (plant ) Tj 1.585542 0 Td 49.899598 Tz (from ) Tj 1.518072 0 Td 42.168675 Tz (a ) Tj 0.556627 0 Td 44.97992 Tz (population ) Tj 3.00241 0 Td 47.791165 Tz (of ) Tj 62.222222 0 0 62.222222 0 1001.321637 Tm 5.175 0 Td 44.53125 Tz (provided ) Tj 2.3625 0 Td 48.214286 Tz (by ) Tj 0.819643 0 Td 34.821429 Tz (this ) Tj 1.092857 0 Td 41.071429 Tz (aspect ) Tj 1.719643 0 Td 45.535714 Tz (of ) Tj 0.707143 0 Td 40.178571 Tz (the ) Tj 0.964286 0 Td 41.964286 Tz (invention ) Tj 2.491071 0 Td 39.030612 Tz (further ) Tj 1.864286 0 Td 44.345238 Tz (comprises ) Tj 3.632143 0 Td 38.839286 Tz (plants ) Tj 1.382143 0 Td 26.785714 Tz (, ) Tj 0.514286 0 Td 45.918367 Tz (wherein ) Tj 2.233929 0 Td 40.178571 Tz (the ) Tj 1.076786 0 Td 39.508929 Tz (selected ) Tj 2.201786 0 Td 40.178571 Tz (plant ) Tj 1.526786 0 Td 44.345238 Tz (comprises ) Tj 2.732143 0 Td 40.178571 Tz (a ) Tj 0.578571 0 Td 45.535714 Tz (genotype ) Tj 57.142857 0 0 57.142857 0 957.453053 Tm 5.6525 0 Td 51.527778 Tz (one ) Tj 1.2425 0 Td 45.208333 Tz (or ) Tj 0.8225 0 Td 55.416667 Tz (more ) Tj 1.645 0 Td 35.486111 Tz (traits ) Tj 1.645 0 Td 43.020833 Tz (selected ) Tj 2.38 0 Td 52.5 Tz (from ) Tj 1.5575 0 Td 43.75 Tz (the ) Tj 1.1025 0 Td 49.583333 Tz (group ) Tj 1.8375 0 Td 43.75 Tz (consisting ) Tj 2.94 0 Td 49.583333 Tz (of ) Tj 1.8725 0 Td 44.625 Tz (associated ) Tj 2.9575 0 Td 48.125 Tz (with ) Tj 1.4525 0 Td 65.138889 Tz (FHB ) Tj 1.33 0 Td 26.25 Tz (- ) Tj 0.1575 0 Td 42 Tz (resistance ) Tj 2.555 0 Td 26.25 Tz (, ) Tj 0.4725 0 Td 51.527778 Tz (and ) Tj 1.2075 0 Td 50.416667 Tz (wherein ) Tj 2.38 0 Td 43.75 Tz (the ) Tj 1.12 0 Td 43.385417 Tz (selected ) Tj 60.748299 0 0 60.748299 0 917.937379 Tm 5.30056 0 Td 42.372776 Tz (herbicide ) Tj 2.53505 0 Td 42.372776 Tz (tolerance ) Tj 2.222284 0 Td 24.692049 Tz (, ) Tj 0.444457 0 Td 42.982456 Tz (increased ) Tj 2.551512 0 Td 41.702128 Tz (yield ) Tj 1.267525 0 Td 13.717805 Tz (, ) Tj 0.378611 0 Td 39.324375 Tz (insect ) Tj 1.695521 0 Td 41.545353 Tz (control ) Tj 1.695521 0 Td 24.692049 Tz (, ) Tj 0.444457 0 Td 42.525196 Tz (fungal ) Tj 2.781971 0 Td 40.055991 Tz (plant ) Tj 1.547368 0 Td 42.525196 Tz (or ) Tj 0.823068 0 Td 47.032475 Tz (progeny ) Tj 2.28813 0 Td 42.721165 Tz (thereof ) Tj 2.057671 0 Td 39.977604 Tz (exhibit ) Tj 2.008287 0 Td 59.443822 Tz (FHB ) Tj 1.300448 0 Td 19.204927 Tz (- ) Tj 0.082307 0 Td 39.781635 Tz (resistance ) Tj 2.452744 0 Td 19.204927 Tz (. ) Tj 0.444457 0 Td 41.153415 Tz (In ) Tj 0.855991 0 Td 52.12766 Tz (pre ) Tj 64.285714 0 0 64.285714 0 871.910305 Tm 5.024444 0 Td 39.62963 Tz (disease ) Tj 1.975556 0 Td 38.62963 Tz (resistance ) Tj 2.286667 0 Td 23.333333 Tz (, ) Tj 0.466667 0 Td 37.851852 Tz (virus ) Tj 1.462222 0 Td 38.111111 Tz (resistance ) Tj 2.333333 0 Td 12.962963 Tz (, ) Tj 0.42 0 Td 46.990741 Tz (nematode ) Tj 2.566667 0 Td 38.111111 Tz (resistance ) Tj 2.333333 0 Td 12.962963 Tz (, ) Tj 0.482222 0 Td 35 Tz (50 ) Tj 0.824444 0 Td 38.45679 Tz (ferred ) Tj 1.633333 0 Td 46.666667 Tz (embodiments ) Tj 3.095556 0 Td 23.333333 Tz (, ) Tj 0.42 0 Td 38.888889 Tz (the ) Tj 0.948889 0 Td 38.888889 Tz (plant ) Tj 1.431111 0 Td 28.518519 Tz (is ) Tj 0.653333 0 Td 38.240741 Tz (selected ) Tj 2.1 0 Td 46.666667 Tz (from ) Tj 1.353333 0 Td 39.753086 Tz (the ) Tj 0.98 0 Td 43.555556 Tz (group ) Tj 59.285714 0 0 59.285714 0 834.566561 Tm 5.431325 0 Td 39.982151 Tz (bacterial ) Tj 2.361446 0 Td 42.570281 Tz (disease ) Tj 1.973494 0 Td 39.919679 Tz (resistance ) Tj 2.462651 0 Td 25.301205 Tz (, ) Tj 0.354217 0 Td 53.13253 Tz (mycoplasma ) Tj 3.373494 0 Td 42.971888 Tz (disease ) Tj 1.990361 0 Td 41.325301 Tz (resistance ) Tj 2.496386 0 Td 25.301205 Tz (, ) Tj 1.416867 0 Td 42.168675 Tz (consisting ) Tj 2.766265 0 Td 47.791165 Tz (of ) Tj 0.725301 0 Td 50.040161 Tz (wheat ) Tj 1.737349 0 Td 49.665328 Tz (and ) Tj 1.096386 0 Td 41.700134 Tz (barley ) Tj 1.501205 0 Td 28.11245 Tz (. ) Tj 58.968254 0 0 58.968254 0 795.54132 Tm 5.460565 0 Td 46.98856 Tz (modified ) Tj 2.492867 0 Td 36.036339 Tz (oils ) Tj 1.119246 0 Td 44.656797 Tz (production ) Tj 2.696366 0 Td 28.263795 Tz (, ) Tj 0.423957 0 Td 47.341857 Tz (high ) Tj 1.356662 0 Td 35.800808 Tz (oil ) Tj 0.88183 0 Td 44.656797 Tz (production ) Tj 2.696366 0 Td 28.263795 Tz (, ) Tj 0.423957 0 Td 47.341857 Tz (high ) Tj 1.339704 0 Td 43.20323 Tz (protein ) Tj 3.730821 0 Td 53.701211 Tz (The ) Tj 1.187079 0 Td 43.606999 Tz (present ) Tj 2.06891 0 Td 44.279946 Tz (invention ) Tj 2.611575 0 Td 40.982503 Tz (also ) Tj 1.220996 0 Td 45.222073 Tz (provides ) Tj 2.408075 0 Td 41.453567 Tz (plants ) Tj 1.746703 0 Td 47.200538 Tz (comprising ) Tj 3.086406 0 Td 42.395693 Tz (a ) Tj 60 0 0 60 0 753.235219 Tm 5.366667 0 Td 43.611111 Tz (production ) Tj 2.7 0 Td 27.777778 Tz (, ) Tj 0.666667 0 Td 45.454545 Tz (germination ) Tj 3.5 0 Td 49.074074 Tz (and ) Tj 1.4 0 Td 42.361111 Tz (seedling ) Tj 2.55 0 Td 48.611111 Tz (growth ) Tj 2.25 0 Td 42.857143 Tz (control ) Tj 1.75 0 Td 25 Tz (, ) Tj 1.416667 0 Td 44.444444 Tz (heterologous ) Tj 3.433333 0 Td 47.222222 Tz (recombinant ) Tj 3.366667 0 Td 44.166667 Tz (expression ) Tj 2.883333 0 Td 40.277778 Tz (cassette ) Tj 1.916667 0 Td 22.222222 Tz (, ) Tj 0.383333 0 Td 48.015873 Tz (wherein ) Tj 2.216667 0 Td 42.592593 Tz (the ) Tj 58.571429 0 0 58.571429 0 709.305625 Tm 5.514634 0 Td 50.152439 Tz (enhanced ) Tj 2.560976 0 Td 47.425474 Tz (animal ) Tj 1.895122 0 Td 50.271003 Tz (and ) Tj 1.041463 0 Td 58.617886 Tz (human ) Tj 1.895122 0 Td 39.521229 Tz (nutrition ) Tj 2.168293 0 Td 25.609756 Tz (, ) Tj 0.358537 0 Td 48.373984 Tz (lower ) Tj 1.587805 0 Td 39.521229 Tz (raffinose ) Tj 2.15122 0 Td 25.609756 Tz (, ) Tj 0.392683 0 Td 42.682927 Tz (envi- ) Tj 2.560976 0 Td 42.113821 Tz (plant ) Tj 1.519512 0 Td 45.528455 Tz (has ) Tj 1.109756 0 Td 50.152439 Tz (enhanced ) Tj 2.663415 0 Td 63.550136 Tz (FHB ) Tj 1.297561 0 Td 19.918699 Tz (- ) Tj 0.170732 0 Td 41.260163 Tz (resistance ) Tj 2.74878 0 Td 52.286585 Tz (compared ) Tj 2.74878 0 Td 38.414634 Tz (to ) Tj 0.75122 0 Td 42.682927 Tz (a ) Tj 0.529268 0 Td 42.276423 Tz (control ) Tj 64.285714 0 0 64.285714 0 666.261749 Tm 5.008889 0 Td 43.209877 Tz (ronmental ) Tj 2.582222 0 Td 34.567901 Tz (stress ) Tj 1.462222 0 Td 38.111111 Tz (resistance ) Tj 2.333333 0 Td 12.962963 Tz (, ) Tj 0.326667 0 Td 40.329218 Tz (increased ) Tj 2.395556 0 Td 35.498575 Tz (digestibility ) Tj 2.722222 0 Td 25.925926 Tz (, ) Tj 0.342222 0 Td 42.592593 Tz (produc- ) Tj 2.177778 0 Td 33.703704 Tz (55 ) Tj 0.808889 0 Td 38.37037 Tz (plant ) Tj 1.306667 0 Td 40.37037 Tz (lacking ) Tj 1.835556 0 Td 38.888889 Tz (the ) Tj 0.855556 0 Td 41.481481 Tz (expression ) Tj 2.628889 0 Td 36.944444 Tz (cassette ) Tj 1.773333 0 Td 20.740741 Tz (, ) Tj 0.295556 0 Td 38.888889 Tz (the ) Tj 0.855556 0 Td 41.481481 Tz (expression ) Tj 2.628889 0 Td 37.268519 Tz (cassette ) Tj 61.344538 0 0 61.344538 0 630.115672 Tm 5.249041 0 Td 40.074201 Tz (tion ) Tj 1.255205 0 Td 46.187215 Tz (of ) Tj 0.798767 0 Td 37.76484 Tz (industrial ) Tj 2.591918 0 Td 50.844749 Tz (enzymes ) Tj 2.135479 0 Td 19.018265 Tz (, ) Tj 0.407534 0 Td 44.285388 Tz (production ) Tj 2.950548 0 Td 46.187215 Tz (of ) Tj 0.782466 0 Td 44.246575 Tz (pharmaceutical ) Tj 4.955616 0 Td 45.643836 Tz (comprising ) Tj 2.934247 0 Td 38.03653 Tz (a ) Tj 0.423836 0 Td 46.866438 Tz (promoter ) Tj 2.412603 0 Td 44.149543 Tz (operably ) Tj 2.314795 0 Td 41.659056 Tz (linked ) Tj 1.695342 0 Td 38.03653 Tz (to ) Tj 0.652055 0 Td 38.03653 Tz (a ) Tj 0.423836 0 Td 42.5 Tz (polynucleotide ) Tj 3.586301 0 Td 27.16895 Tz (, ) Tj 61.428571 0 0 61.428571 0 587.985354 Tm 5.24186 0 Td 42.393411 Tz (proteins ) Tj 1.953488 0 Td 27.131783 Tz (, ) Tj 0.325581 0 Td 43.953488 Tz (production ) Tj 2.816279 0 Td 46.124031 Tz (of ) Tj 0.651163 0 Td 44.186047 Tz (pharmaceutical ) Tj 3.890698 0 Td 41.375969 Tz (peptides ) Tj 1.986047 0 Td 27.131783 Tz (, ) Tj 0.35814 0 Td 44.224806 Tz (production ) Tj 3.874419 0 Td 49.922481 Tz (which ) Tj 1.611628 0 Td 42.829457 Tz (polynucleotide ) Tj 3.613953 0 Td 27.131783 Tz (, ) Tj 0.293023 0 Td 54.94186 Tz (when ) Tj 1.465116 0 Td 43.712317 Tz (expressed ) Tj 2.360465 0 Td 27.131783 Tz (, ) Tj 0.325581 0 Td 40.697674 Tz (increases ) Tj 2.360465 0 Td 43.139535 Tz (expression ) Tj 61.507937 0 0 61.507937 0 544.755556 Tm 5.251355 0 Td 46.064516 Tz (of ) Tj 0.796645 0 Td 43.935484 Tz (pharmaceutical ) Tj 4.048258 0 Td 42.270968 Tz (small ) Tj 1.59329 0 Td 45.16129 Tz (molecules ) Tj 2.487484 0 Td 13.548387 Tz (, ) Tj 0.438968 0 Td 48.096774 Tz (improved ) Tj 2.617548 0 Td 43.354839 Tz (processing ) Tj 3.853161 0 Td 46.064516 Tz (of ) Tj 0.682839 0 Td 46.064516 Tz (an ) Tj 0.731613 0 Td 58.258065 Tz (FHB1 ) Tj 1.642065 0 Td 41.032258 Tz (protein ) Tj 1.918452 0 Td 49.451613 Tz (compared ) Tj 2.552516 0 Td 36.580645 Tz (to ) Tj 0.650323 0 Td 40.645161 Tz (a ) Tj 0.438968 0 Td 40.258065 Tz (control ) Tj 1.885935 0 Td 40.103226 Tz (plant ) Tj 1.398194 0 Td 41.806452 Tz (lacking ) Tj 1.93471 0 Td 40.645161 Tz (the ) Tj 59.159664 0 0 59.159664 0 503.735786 Tm 5.442898 0 Td 34.745896 Tz (traits ) Tj 1.233949 0 Td 25.355114 Tz (, ) Tj 0.828267 0 Td 50.358073 Tz (improved ) Tj 3.042614 0 Td 42.728062 Tz (flavor ) Tj 1.453693 0 Td 25.355114 Tz (, ) Tj 0.777557 0 Td 50.358073 Tz (improved ) Tj 3.02571 0 Td 44.019295 Tz (nitrogen ) Tj 2.755256 0 Td 37.680516 Tz (fixation ) Tj 1.893182 0 Td 25.355114 Tz (, ) Tj 1.453693 0 Td 44.794034 Tz (expression ) Tj 3.02571 0 Td 41.20206 Tz (cassette ) Tj 1.943892 0 Td 22.537879 Tz (, ) Tj 0.490199 0 Td 48.295455 Tz (wherein ) Tj 2.366477 0 Td 44.136679 Tz (increased ) Tj 2.704545 0 Td 45.075758 Tz (expression ) Tj 3.02571 0 Td 47.892992 Tz (of ) Tj 0.828267 0 Td 43.197601 Tz (the ) Tj 65.714286 0 0 65.714286 0 462.920166 Tm 4.930435 0 Td 44.384058 Tz (improved ) Tj 2.282609 0 Td 40.57971 Tz (hybrid ) Tj 1.643478 0 Td 40.57971 Tz (seed ) Tj 1.126087 0 Td 40.57971 Tz (production ) Tj 2.404348 0 Td 32.971014 Tz (, ) Tj 0.365217 0 Td 42.028986 Tz (reduced ) Tj 1.917391 0 Td 36.287625 Tz (allergenicity ) Tj 2.73913 0 Td 32.971014 Tz (, ) Tj 0.334783 0 Td 45.652174 Tz (and ) Tj 1.186957 0 Td 35.507246 Tz (60 ) Tj 0.821739 0 Td 53.26087 Tz (FHB1 ) Tj 1.491304 0 Td 38.405797 Tz (protein ) Tj 1.765217 0 Td 34.782609 Tz (results ) Tj 1.613043 0 Td 35.507246 Tz (in ) Tj 0.578261 0 Td 44.384058 Tz (enhanced ) Tj 2.282609 0 Td 59.178744 Tz (FHB ) Tj 1.141304 0 Td 25.362319 Tz (- ) Tj 0.213043 0 Td 36.268116 Tz (resistance ) Tj 2.328261 0 Td 45.652174 Tz (compared ) Tj 63.642857 0 0 63.642857 0 418.134796 Tm 5.075196 0 Td 46.8107 Tz (improved ) Tj 2.419753 0 Td 42.424242 Tz (production ) Tj 2.749719 0 Td 43.209877 Tz (of ) Tj 0.64422 0 Td 44.281196 Tz (biopolymers ) Tj 3.142536 0 Td 46.26512 Tz (and ) Tj 1.005612 0 Td 38.954358 Tz (biofuels ) Tj 1.901235 0 Td 18.331463 Tz (. ) Tj 0.345679 0 Td 39.281706 Tz (In ) Tj 0.675645 0 Td 50.411523 Tz (some ) Tj 2.40404 0 Td 35.353535 Tz (to ) Tj 0.659933 0 Td 39.281706 Tz (the ) Tj 0.942761 0 Td 38.907594 Tz (control ) Tj 1.869809 0 Td 39.281706 Tz (plant ) Tj 1.147026 0 Td 26.187804 Tz (. ) Tj 0.392817 0 Td 40.591096 Tz (In ) Tj 0.722783 0 Td 49.756828 Tz (some ) Tj 1.429854 0 Td 47.376118 Tz (embodiments ) Tj 3.126824 0 Td 23.569024 Tz (, ) Tj 0.377104 0 Td 39.281706 Tz (the ) Tj 0.911336 0 Td 47.719998 Tz (polynucle ) Tj 60.672269 0 0 60.672269 0 376.76735 Tm 5.323684 0 Td 49.695711 Tz (embodiments ) Tj 3.543629 0 Td 41.204986 Tz (the ) Tj 0.972438 0 Td 39.678876 Tz (resulting ) Tj 2.389889 0 Td 40.655586 Tz (plant ) Tj 1.466898 0 Td 31.590489 Tz (is ) Tj 0.626316 0 Td 38.152765 Tz (resistant ) Tj 2.290997 0 Td 37.084488 Tz (to ) Tj 0.725208 0 Td 41.204986 Tz (a ) Tj 0.477978 0 Td 42.425875 Tz (herbicide ) Tj 3.560111 0 Td 40.106187 Tz (otide ) Tj 1.582271 0 Td 46.306556 Tz (encodes ) Tj 2.340443 0 Td 41.204986 Tz (a ) Tj 0.609834 0 Td 43.951985 Tz (polypeptide ) Tj 3.279917 0 Td 45.874885 Tz (comprising ) Tj 3.131579 0 Td 48.072484 Tz (an ) Tj 0.939474 0 Td 49.995383 Tz (amino ) Tj 1.895429 0 Td 41.891736 Tz (acid ) Tj 57.566138 0 0 57.566138 0 337.39987 Tm 5.628309 0 Td 42.704504 Tz (selected ) Tj 2.293015 0 Td 50.66636 Tz (from ) Tj 1.459191 0 Td 42.463235 Tz (the ) Tj 0.972794 0 Td 49.797794 Tz (group ) Tj 1.737132 0 Td 43.428309 Tz (consisting ) Tj 2.814154 0 Td 52.113971 Tz (of ) Tj 0.764338 0 Td 46.323529 Tz (glyphosate ) Tj 2.744669 0 Td 28.952206 Tz (, ) Tj 0.416912 0 Td 51.700368 Tz (dicamba ) Tj 2.223529 0 Td 26.056985 Tz (, ) Tj 1.476562 0 Td 48.494945 Tz (sequence ) Tj 2.553585 0 Td 37.637868 Tz (at ) Tj 0.66011 0 Td 39.375 Tz (least ) Tj 1.389706 0 Td 52.113971 Tz (70 ) Tj 0.66011 0 Td 83.961397 Tz (% ) Tj 0.729596 0 Td 40.533088 Tz (identical ) Tj 2.414614 0 Td 39.085478 Tz (to ) Tj 0.712224 0 Td 51.148897 Tz (any ) Tj 1.129136 0 Td 49.21875 Tz (of ) Tj 0.764338 0 Td 64.659926 Tz (SEQ ) Tj 1.407077 0 Td 53.561581 Tz (ID ) Tj 0.851195 0 Td 76.723346 Tz (NO ) Tj 0.990165 0 Td 11.580882 Tz (: ) Tj 0.156342 0 Td 43.428309 Tz (3 ) Tj 0.330055 0 Td 14.476103 Tz (, ) Tj 0.347426 0 Td 46.323529 Tz (7 ) Tj 0.347426 0 Td 14.476103 Tz (, ) Tj 60.408163 0 0 60.408163 0 296.411649 Tm 5.330405 0 Td 41.385135 Tz (glufosinate ) Tj 2.714865 0 Td 27.59009 Tz (, ) Tj 0.69527 0 Td 42.304805 Tz (sulfonylurea ) Tj 3.0625 0 Td 27.59009 Tz (, ) Tj 0.6125 0 Td 48.282658 Tz (bromoxynil ) Tj 2.847297 0 Td 27.59009 Tz (, ) Tj 0.761486 0 Td 35.867117 Tz (2,4 ) Tj 0.711824 0 Td 35.867117 Tz (- ) Tj 0.165541 0 Td 45.293731 Tz (Dichlorophe- ) Tj 4.585473 0 Td 41.385135 Tz (8 ) Tj 0.562838 0 Td 41.385135 Tz (or ) Tj 0.794595 0 Td 41.385135 Tz (9 ) Tj 0.314527 0 Td 13.795045 Tz (, ) Tj 0.380743 0 Td 47.691441 Tz (wherein ) Tj 2.301014 0 Td 40.005631 Tz (said ) Tj 1.225 0 Td 44.144144 Tz (polypeptide ) Tj 3.194932 0 Td 44.144144 Tz (has ) Tj 1.109122 0 Td 59.318694 Tz (FHB1 ) Tj 1.771284 0 Td 38.28125 Tz (activity ) Tj 1.854054 0 Td 11.036036 Tz (. ) Tj 0.380743 0 Td 51.501502 Tz (The ) Tj 60.952381 0 0 60.952381 0 253.489035 Tm 5.266406 0 Td 44.023438 Tz (noxyacetic ) Tj 2.8875 0 Td 41.699219 Tz (acid ) Tj 1.033594 0 Td 13.671875 Tz (, ) Tj 0.344531 0 Td 48.307292 Tz (and ) Tj 1.066406 0 Td 41.761364 Tz (norflurazon ) Tj 2.871094 0 Td 21.875 Tz (. ) Tj 64.285714 0 0 64.285714 0 250.582418 Tm 19.366667 0 Td 32.407407 Tz (65 ) Tj 0.808889 0 Td 40.617284 Tz (invention ) Tj 2.411111 0 Td 37.777778 Tz (further ) Tj 1.788889 0 Td 41.157407 Tz (provides ) Tj 2.224444 0 Td 46.296296 Tz (methods ) Tj 2.208889 0 Td 42.777778 Tz (of ) Tj 0.684444 0 Td 47.962963 Tz (making ) Tj 1.991111 0 Td 43.425926 Tz (such ) Tj 1.26 0 Td 38.024691 Tz (plants ) Tj 59.663866 0 0 59.663866 0 212.563009 Tm 6.050563 0 Td 52.143975 Tz (The ) Tj 1.173239 0 Td 43.763693 Tz (invention ) Tj 2.564366 0 Td 40.704225 Tz (further ) Tj 1.910704 0 Td 44.345657 Tz (provides ) Tj 2.363239 0 Td 49.882629 Tz (methods ) Tj 2.346479 0 Td 46.091549 Tz (of ) Tj 0.703944 0 Td 46.867501 Tz (producing ) Tj 2.765493 0 Td 48.884977 Tz (an ) Tj 1.843662 0 Td 39.107981 Tz (that ) Tj 1.072676 0 Td 42.739437 Tz (preferably ) Tj 2.731972 0 Td 47.488263 Tz (comprise ) Tj 2.430282 0 Td 41.901408 Tz (a ) Tj 0.435775 0 Td 39.806338 Tz (step ) Tj 1.122958 0 Td 47.488263 Tz (of ) Tj 0.670423 0 Td 43.171148 Tz (introducing ) Tj 3.000141 0 Td 41.901408 Tz (the ) Tj 0.921831 0 Td 44.415493 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) Tj 2.425146 0 Td 48.050682 Tz (of ) Tj 0.678363 0 Td 64.067576 Tz (SEQ ) Tj 1.322807 0 Td 52.290448 Tz (ID ) Tj 0.780117 0 Td 74.902534 Tz (NO ) Tj 0.966667 0 Td 11.306043 Tz (: ) Tj 0.152632 0 Td 42.397661 Tz (3 ) Tj 0.322222 0 Td 14.132554 Tz (, ) Tj 0.271345 0 Td 45.224172 Tz (7 ) Tj 0.339181 0 Td 14.132554 Tz (, ) Tj 0.288304 0 Td 42.397661 Tz (8 ) Tj 0.322222 0 Td 14.132554 Tz (, ) Tj 0.271345 0 Td 43.810916 Tz (or ) Tj 0.678363 0 Td 42.397661 Tz (9 ) Tj 0.339181 0 Td 14.132554 Tz (; ) Tj 0.271345 0 Td 43.810916 Tz (or ) Tj 0.661404 0 Td 42.397661 Tz (a ) Tj 0.390058 0 Td 43.205235 Tz (protein ) Tj 3.069591 0 Td 43.457602 Tz (reagents ) Tj 2.323392 0 Td 46.990741 Tz (provided ) Tj 2.476023 0 Td 50.877193 Tz (by ) Tj 0.830994 0 Td 44.01281 Tz (various ) Tj 2.102924 0 Td 42.801448 Tz (aspects ) Tj 2.052047 0 Td 46.637427 Tz (of ) Tj 0.712281 0 Td 37.451267 Tz (this ) Tj 1.153216 0 Td 42.397661 Tz (invention ) Tj 2.408187 0 Td 22.612086 Tz (. ) Tj 57.142857 0 0 57.142857 0 2324.124688 Tm 5.635 0 Td 49.097222 Tz (having ) Tj 1.9775 0 Td 37.916667 Tz (at ) Tj 0.6475 0 Td 39.666667 Tz (least ) Tj 1.3825 0 Td 47.833333 Tz (about ) Tj 1.645 0 Td 51.041667 Tz (70 ) Tj 0.6475 0 Td 84.583333 Tz (% ) Tj 0.7175 0 Td 53.083333 Tz (amino ) Tj 1.82 0 Td 45.208333 Tz (acid ) Tj 1.2775 0 Td 40.833333 Tz (identity ) Tj 2.1525 0 Td 48.854167 Tz (with ) Tj 1.3825 0 Td 66.111111 Tz (SEQ ) Tj 1.4 0 Td 53.958333 Tz (ID ) Tj 1.12 0 Td 35 Tz (15 ) Tj 55.714286 0 0 55.714286 0 2331.400541 Tm 23.925641 0 Td 50.356125 Tz (Unless ) Tj 2.207692 0 Td 47.863248 Tz (otherwise ) Tj 2.979487 0 Td 45.204179 Tz (indicated ) Tj 2.8 0 Td 55.34188 Tz (by ) Tj 1.023077 0 Td 44.871795 Tz (the ) Tj 1.202564 0 Td 49.145299 Tz (context ) Tj 1.938462 0 Td 23.931624 Tz (, ) Tj 0.538462 0 Td 45.769231 Tz (references ) Tj 61.857143 0 0 61.857143 0 2284.923984 Tm 5.189376 0 Td 71.401078 Tz (NO ) Tj 0.921478 0 Td 10.777521 Tz (: ) Tj 0.145497 0 Td 40.415704 Tz (3 ) Tj 0.307159 0 Td 13.471901 Tz (, ) Tj 0.323326 0 Td 43.110085 Tz (7 ) Tj 0.323326 0 Td 13.471901 Tz (, ) Tj 0.323326 0 Td 40.415704 Tz (8 ) Tj 0.307159 0 Td 13.471901 Tz (, ) Tj 0.307159 0 Td 41.762895 Tz (or ) Tj 0.711316 0 Td 40.415704 Tz (9 ) Tj 0.468822 0 Td 47.600719 Tz (and ) Tj 1.034642 0 Td 39.517578 Tz (retaining ) Tj 2.327945 0 Td 40.415704 Tz (the ) Tj 0.937644 0 Td 40.415704 Tz (functional ) Tj 2.635104 0 Td 38.080575 Tz (characteristics ) Tj 4.672055 0 Td 42.211958 Tz (herein ) Tj 1.69746 0 Td 36.374134 Tz (to ) Tj 0.662818 0 Td 40.415704 Tz (a ) Tj 0.501155 0 Td 32.332564 Tz ( ) Tj 0.242494 0 Td 42.032333 Tz (plant ) Tj 1.196305 0 Td 32.332564 Tz ( ) Tj 0.43649 0 Td 41.762895 Tz (or ) Tj 0.743649 0 Td 32.332564 Tz ( ) Tj 0.258661 0 Td 38.170387 Tz (plants ) Tj 1.422633 0 Td 32.332564 Tz ( ) Tj 0.420323 0 Td 41.426097 Tz (includes ) Tj 2.182448 0 Td 49.037721 Tz (whole ) Tj 1.665127 0 Td 39.966641 Tz (plants ) Tj 1.406467 0 Td 26.943803 Tz (, ) Tj 0.404157 0 Td 42.571209 Tz (shoot ) Tj 61.428571 0 0 61.428571 0 2240.059524 Tm 5.25814 0 Td 46.124031 Tz (of ) Tj 0.716279 0 Td 40.697674 Tz (the ) Tj 0.960465 0 Td 41.085271 Tz (protein ) Tj 1.937209 0 Td 45.671835 Tz (having ) Tj 1.872093 0 Td 40.697674 Tz (the ) Tj 0.976744 0 Td 49.379845 Tz (amino ) Tj 1.74186 0 Td 42.054264 Tz (acid ) Tj 1.253488 0 Td 45.445736 Tz (sequence ) Tj 2.425581 0 Td 46.124031 Tz (of ) Tj 0.748837 0 Td 60.594315 Tz (SEQ ) Tj 1.351163 0 Td 50.193798 Tz (ID ) Tj 62.857143 0 0 62.857143 0 2251.316364 Tm 20.618182 0 Td 40.833333 Tz (vegetative ) Tj 2.640909 0 Td 43.308081 Tz (organs ) Tj 1.575 0 Td 34.469697 Tz (/ ) Tj 0.206818 0 Td 37.121212 Tz (structures ) Tj 2.45 0 Td 26.515152 Tz (\( ) Tj 0.190909 0 Td 34.469697 Tz (e.g. ) Tj 1.05 0 Td 41.098485 Tz (leaves ) Tj 1.431818 0 Td 26.515152 Tz (, ) Tj 0.381818 0 Td 48.787879 Tz (stems ) Tj 1.527273 0 Td 47.727273 Tz (and ) Tj 1.05 0 Td 39.330808 Tz (tubers ) Tj 1.543182 0 Td 26.515152 Tz (\) ) Tj 0.047727 0 Td 26.515152 Tz (, ) Tj 59.234694 0 0 59.234694 0 2201.512064 Tm 5.419121 0 Td 74.562159 Tz (NO ) Tj 0.962274 0 Td 11.254666 Tz (: ) Tj 0.151938 0 Td 42.204996 Tz (3 ) Tj 0.320758 0 Td 14.068332 Tz (, ) Tj 0.286994 0 Td 35.874246 Tz (e.g. ) Tj 0.92851 0 Td 14.068332 Tz (, ) Tj 0.270112 0 Td 42.204996 Tz (the ) Tj 0.92851 0 Td 37.78352 Tz (ability ) Tj 1.738846 0 Td 39.391329 Tz (to ) Tj 0.658398 0 Td 44.549718 Tz (confer ) Tj 1.738846 0 Td 41.360896 Tz (resistance ) Tj 2.633592 0 Td 37.984496 Tz (to ) Tj 0.641516 0 Td 65.652216 Tz (FHB ) Tj 1.26615 0 Td 11.254666 Tz (. ) Tj 0.270112 0 Td 42.204996 Tz (In ) Tj 0.67528 0 Td 40.597186 Tz (certain ) Tj 2.988114 0 Td 40.516796 Tz (roots ) Tj 1.299914 0 Td 22.509331 Tz (, ) Tj 0.557106 0 Td 43.410853 Tz (flowers ) Tj 2.295952 0 Td 49.708106 Tz (and ) Tj 1.333678 0 Td 35.639774 Tz (floral ) Tj 1.755728 0 Td 45.018662 Tz (organs ) Tj 1.671318 0 Td 28.136664 Tz (/ ) Tj 0.202584 0 Td 39.672696 Tz (structures ) Tj 2.86994 0 Td 28.136664 Tz (\( ) Tj 0.185702 0 Td 35.874246 Tz (e.g. ) Tj 1.316796 0 Td 41.267107 Tz (bracts ) Tj 1.553144 0 Td 14.068332 Tz (, ) Tj 60.12987 0 0 60.12987 0 2162.471493 Tm 5.355076 0 Td 42.192625 Tz (preferred ) Tj 2.561123 0 Td 50.647948 Tz (embodiments ) Tj 3.326134 0 Td 24.946004 Tz (, ) Tj 0.449028 0 Td 41.576674 Tz (the ) Tj 1.031102 0 Td 48.660107 Tz (exogenous ) Tj 2.926998 0 Td 41.972642 Tz (nucleic ) Tj 2.078834 0 Td 42.962563 Tz (acid ) Tj 1.330454 0 Td 51.970842 Tz (com- ) Tj 2.511231 0 Td 42.038637 Tz (sepals ) Tj 1.48013 0 Td 24.946004 Tz (, ) Tj 0.415767 0 Td 39.728822 Tz (petals ) Tj 1.396976 0 Td 27.717783 Tz (, ) Tj 0.49892 0 Td 48.308135 Tz (stamens ) Tj 1.962419 0 Td 22.174226 Tz (, ) Tj 0.432397 0 Td 41.180706 Tz (carpels ) Tj 1.779482 0 Td 13.858891 Tz (, ) Tj 0.399136 0 Td 41.972642 Tz (anthers ) Tj 2.045572 0 Td 49.892009 Tz (and ) Tj 1.164147 0 Td 43.886489 Tz (ovules ) Tj 1.629806 0 Td 27.717783 Tz (\) ) Tj 0.216199 0 Td 13.858891 Tz (, ) Tj 0.415767 0 Td 43.655508 Tz (seed ) Tj 64.857143 0 0 64.857143 0 2120.597656 Tm 4.949339 0 Td 36.833089 Tz (prises ) Tj 1.526432 0 Td 25.697504 Tz (\( ) Tj 0.185022 0 Td 38.546256 Tz (a ) Tj 0.246696 0 Td 25.697504 Tz (\) ) Tj 0.354626 0 Td 38.546256 Tz (a ) Tj 0.400881 0 Td 39.831131 Tz (nucleotide ) Tj 2.57489 0 Td 43.364537 Tz (sequence ) Tj 2.26652 0 Td 43.685756 Tz (of ) Tj 0.647577 0 Td 57.391092 Tz (SEQ ) Tj 1.218062 0 Td 48.825257 Tz (ID ) Tj 0.755507 0 Td 68.098385 Tz (NO ) Tj 0.878855 0 Td 10.279001 Tz (: ) Tj 0.169604 0 Td 25.697504 Tz (1 ) Tj 0.262115 0 Td 12.848752 Tz (, ) Tj 0.277533 0 Td 41.116006 Tz (2 ) Tj 0.30837 0 Td 12.848752 Tz (, ) Tj 0.277533 0 Td 41.116006 Tz (4 ) Tj 0.30837 0 Td 12.848752 Tz (, ) Tj 0.292952 0 Td 35.976505 Tz (5 ) Tj 0.431718 0 Td 39.831131 Tz (or ) Tj 0.832599 0 Td 34.69163 Tz (20 ) Tj 0.832599 0 Td 25.697504 Tz (\( ) Tj 0.169604 0 Td 39.973895 Tz (including ) Tj 2.328194 0 Td 47.540382 Tz (embryo ) Tj 1.726872 0 Td 25.697504 Tz (, ) Tj 0.323789 0 Td 42.258117 Tz (endosperm ) Tj 2.46696 0 Td 25.697504 Tz (, ) Tj 0.354626 0 Td 45.398923 Tz (and ) Tj 1.002203 0 Td 41.116006 Tz (seed ) Tj 1.156388 0 Td 40.473568 Tz (coat ) Tj 0.955947 0 Td 25.697504 Tz (\) ) Tj 0.339207 0 Td 45.398923 Tz (and ) Tj 0.971366 0 Td 32.892805 Tz (fruit ) Tj 1.156388 0 Td 25.697504 Tz (\( ) Tj 0.262115 0 Td 33.406755 Tz (the ) Tj 61.428571 0 0 61.428571 0 2072.901639 Tm 5.274419 0 Td 40.697674 Tz (6 ) Tj 0.325581 0 Td 13.565891 Tz (; ) Tj 0.35814 0 Td 40.697674 Tz (or ) Tj 0.732558 0 Td 27.131783 Tz (\( ) Tj 0.17907 0 Td 46.124031 Tz (b ) Tj 0.325581 0 Td 27.131783 Tz (\) ) Tj 0.423256 0 Td 40.697674 Tz (a ) Tj 0.472093 0 Td 42.054264 Tz (nucleotide ) Tj 2.783721 0 Td 45.784884 Tz (sequence ) Tj 2.425581 0 Td 45.671835 Tz (having ) Tj 1.888372 0 Td 35.271318 Tz (at ) Tj 0.667442 0 Td 36.356589 Tz (least ) Tj 1.334884 0 Td 44.496124 Tz (about ) Tj 1.57907 0 Td 47.48062 Tz (70 ) Tj 0.602326 0 Td 78.682171 Tz (% ) Tj 61.428571 0 0 61.428571 0 2082.753036 Tm 21.097674 0 Td 46.576227 Tz (mature ) Tj 2.018605 0 Td 43.410853 Tz (ovary ) Tj 1.432558 0 Td 27.131783 Tz (\) ) Tj 0.113953 0 Td 27.131783 Tz (, ) Tj 0.504651 0 Td 40.155039 Tz (plant ) Tj 1.530233 0 Td 37.984496 Tz (tissue ) Tj 1.725581 0 Td 27.131783 Tz (\( ) Tj 0.195349 0 Td 33.914729 Tz (e.g. ) Tj 1.172093 0 Td 42.393411 Tz (vascular ) Tj 2.344186 0 Td 38.436693 Tz (tissue ) Tj 1.416279 0 Td 13.565891 Tz (, ) Tj 0.455814 0 Td 47.48062 Tz (ground ) Tj 60 0 0 60 0 2036.914493 Tm 5.383333 0 Td 46.875 Tz (sequence ) Tj 2.5 0 Td 39.236111 Tz (identity ) Tj 2.133333 0 Td 37.5 Tz (to ) Tj 0.75 0 Td 62.962963 Tz (SEQ ) Tj 1.4 0 Td 52.777778 Tz (ID ) Tj 0.883333 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.183333 0 Td 27.777778 Tz (1 ) Tj 0.283333 0 Td 13.888889 Tz (, ) Tj 0.383333 0 Td 44.444444 Tz (2 ) Tj 0.316667 0 Td 13.888889 Tz (, ) Tj 0.383333 0 Td 44.444444 Tz (4 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 0.383333 0 Td 38.888889 Tz (5 ) Tj 0.533333 0 Td 43.055556 Tz (or ) Tj 0.783333 0 Td 31.944444 Tz (6. ) Tj 0.683333 0 Td 41.666667 Tz (In ) Tj 0.766667 0 Td 53.472222 Tz (some ) Tj 2.566667 0 Td 39.351852 Tz (tissue ) Tj 1.45 0 Td 13.888889 Tz (, ) Tj 0.4 0 Td 49.074074 Tz (and ) Tj 1.133333 0 Td 41.666667 Tz (the ) Tj 1.033333 0 Td 37.5 Tz (like ) Tj 0.933333 0 Td 27.777778 Tz (\) ) Tj 0.45 0 Td 50 Tz (and ) Tj 1.15 0 Td 36.666667 Tz (cells ) Tj 1.416667 0 Td 27.777778 Tz (\( ) Tj 0.2 0 Td 34.722222 Tz (e.g. ) Tj 1.15 0 Td 46.666667 Tz (guard ) Tj 1.666667 0 Td 36.666667 Tz (cells ) Tj 1.166667 0 Td 13.888889 Tz (, ) Tj 0.383333 0 Td 48.148148 Tz (egg ) Tj 1.15 0 Td 36.666667 Tz (cells ) Tj 1.166667 0 Td 13.888889 Tz (, ) Tj 61.142857 0 0 61.142857 0 1990.030377 Tm 5.28271 0 Td 50.056641 Tz (embodiments ) Tj 3.271028 0 Td 24.53271 Tz (, ) Tj 0.294393 0 Td 40.88785 Tz (the ) Tj 0.866822 0 Td 41.978193 Tz (toxin ) Tj 1.406542 0 Td 29.984424 Tz (is ) Tj 0.556075 0 Td 40.206386 Tz (selected ) Tj 2.077103 0 Td 48.383956 Tz (from ) Tj 1.292056 0 Td 40.88785 Tz (the ) Tj 0.899533 0 Td 45.794393 Tz (group ) Tj 1.553738 0 Td 40.88785 Tz (consisting ) Tj 60 0 0 60 0 1997.43342 Tm 21.6 0 Td 45.061728 Tz (trichomes ) Tj 2.666667 0 Td 50 Tz (and ) Tj 1.083333 0 Td 41.666667 Tz (the ) Tj 0.966667 0 Td 38.194444 Tz (like ) Tj 0.95 0 Td 27.777778 Tz (\) ) Tj 0.216667 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 49.074074 Tz (and ) Tj 1.083333 0 Td 48.412698 Tz (progeny ) Tj 2.25 0 Td 47.222222 Tz (of ) Tj 0.733333 0 Td 52.777778 Tz (same ) Tj 1.3 0 Td 13.888889 Tz (. ) Tj 0.316667 0 Td 51.851852 Tz (The ) Tj 1.15 0 Td 39.444444 Tz (class ) Tj 1.416667 0 Td 47.222222 Tz (of ) Tj 62.539683 0 0 62.539683 0 1949.639521 Tm 5.164721 0 Td 45.304569 Tz (of ) Tj 0.687563 0 Td 43.705584 Tz (fumonisins ) Tj 2.846193 0 Td 47.969543 Tz (and ) Tj 1.03934 0 Td 40.545685 Tz (trichothecenes ) Tj 3.469797 0 Td 23.984772 Tz (, ) Tj 0.335787 0 Td 38.19797 Tz (particularly ) Tj 2.958122 0 Td 63.959391 Tz (De ) Tj 0.767513 0 Td 31.979695 Tz (- ) Tj 0.191878 0 Td 49.111675 Tz (oxyniva ) Tj 56.071429 0 0 56.071429 0 1958.06768 Tm 23.095541 0 Td 43.595188 Tz (plants ) Tj 1.854777 0 Td 41.613588 Tz (that ) Tj 1.301911 0 Td 50.530786 Tz (can ) Tj 1.17707 0 Td 52.016985 Tz (be ) Tj 0.89172 0 Td 50.530786 Tz (used ) Tj 1.533758 0 Td 40.127389 Tz (in ) Tj 0.749045 0 Td 44.585987 Tz (the ) Tj 1.087898 0 Td 55.980184 Tz (method ) Tj 2.300637 0 Td 49.044586 Tz (of ) Tj 0.802548 0 Td 44.585987 Tz (the ) Tj 1.105732 0 Td 46.23732 Tz (invention ) Tj 2.782166 0 Td 34.18259 Tz (is ) Tj 59.714286 0 0 59.714286 0 1904.847826 Tm 5.392344 0 Td 41.866029 Tz (lenol ) Tj 1.473684 0 Td 39.07496 Tz (\( ) Tj 0.184211 0 Td 67.916002 Tz (DON ) Tj 1.423445 0 Td 30.701754 Tz (\) ) Tj 0.100478 0 Td 30.701754 Tz (. ) Tj 58.571429 0 0 58.571429 0 1916.727742 Tm 21.239024 0 Td 36.99187 Tz (25 ) Tj 0.904878 0 Td 43.315266 Tz (generally ) Tj 2.612195 0 Td 41.260163 Tz (as ) Tj 0.75122 0 Td 48.373984 Tz (broad ) Tj 1.707317 0 Td 39.837398 Tz (as ) Tj 0.75122 0 Td 42.682927 Tz (the ) Tj 1.02439 0 Td 39.837398 Tz (class ) Tj 1.485366 0 Td 46.95122 Tz (of ) Tj 0.75122 0 Td 45.528455 Tz (higher ) Tj 1.878049 0 Td 50.271003 Tz (and ) Tj 1.160976 0 Td 48.373984 Tz (lower ) Tj 1.673171 0 Td 41.734417 Tz (plants ) Tj 58.979592 0 0 58.979592 0 1877.79397 Tm 21.990657 0 Td 50.158593 Tz (amenable ) Tj 2.746713 0 Td 39.561707 Tz (to ) Tj 0.830796 0 Td 44.607843 Tz (transformation ) Tj 4.069204 0 Td 45.495963 Tz (techniques ) Tj 2.661938 0 Td 28.258362 Tz (, ) Tj 0.559516 0 Td 43.957452 Tz (including ) Tj 2.746713 0 Td 53.125721 Tz (angio ) Tj 44.285714 0 0 44.285714 0 1835 Tm 9.325806 0 Td 78.27957 Tz (BRIEF ) Tj 2.687097 0 Td 82.795699 Tz (DESCRIPTION ) Tj 5.780645 0 Td 84.677419 Tz (OF ) Tj 1.332258 0 Td 89.0681 Tz (THE ) Tj 1.919355 0 Td 92.204301 Tz (DRAWINGS ) Tj 60.892857 0 0 60.892857 0 1836.81178 Tm 21.299707 0 Td 46.529814 Tz (sperms ) Tj 2.15132 0 Td 27.370479 Tz (\( ) Tj 0.180645 0 Td 48.411535 Tz (monocotyledonous ) Tj 5.107331 0 Td 48.354513 Tz (and ) Tj 1.297361 0 Td 44.183773 Tz (dicotyledonous ) Tj 4.154839 0 Td 39.687195 Tz (plants ) Tj 1.560117 0 Td 27.370479 Tz (\) ) Tj 0.098534 0 Td 27.370479 Tz (, ) Tj 61.714286 0 0 61.714286 0 1791.127108 Tm 21 0 Td 51.557239 Tz (gymnosperms ) Tj 3.386574 0 Td 18.904321 Tz (, ) Tj 0.469907 0 Td 39.969136 Tz (ferns ) Tj 1.166667 0 Td 24.305556 Tz (, ) Tj 0.502315 0 Td 48.611111 Tz (and ) Tj 1.166667 0 Td 39.88604 Tz (multicellular ) Tj 3.418981 0 Td 42.12963 Tz (algae ) Tj 1.3125 0 Td 10.802469 Tz (. ) Tj 0.4375 0 Td 28.356481 Tz (It ) Tj 0.680556 0 Td 41.184414 Tz (includes ) Tj 59.130435 0 0 59.130435 0 1748.955801 Tm 6.105147 0 Td 55.433007 Tz (FIG ) Tj 1.048529 0 Td 11.27451 Tz (. ) Tj 0.422794 0 Td 32.414216 Tz (1. ) Tj 0.727206 0 Td 54.963235 Tz (Gene ) Tj 1.640441 0 Td 40.087146 Tz (structure ) Tj 2.469118 0 Td 47.916667 Tz (of ) Tj 0.811765 0 Td 54.258578 Tz (Fhbl ) Tj 1.319118 0 Td 19.730392 Tz (. ) Tj 0.422794 0 Td 51.439951 Tz (Grey ) Tj 1.522059 0 Td 48.480392 Tz (boxes ) Tj 1.792647 0 Td 53.553922 Tz (show ) Tj 1.589706 0 Td 42.279412 Tz (the ) Tj 2.046324 0 Td 41.339869 Tz (plants ) Tj 1.792647 0 Td 50.735294 Tz (of ) Tj 0.811765 0 Td 45.098039 Tz (a ) Tj 0.575 0 Td 41.071429 Tz (variety ) Tj 2.063235 0 Td 47.916667 Tz (of ) Tj 0.811765 0 Td 44.158497 Tz (ploidy ) Tj 1.894118 0 Td 41.809641 Tz (levels ) Tj 1.454412 0 Td 25.367647 Tz (, ) Tj 0.473529 0 Td 43.845316 Tz (including ) Tj 2.672059 0 Td 43.845316 Tz (aneuploid ) Tj 2.486029 0 Td 28.186275 Tz (, ) Tj 63.428571 0 0 63.428571 0 1706.765157 Tm 5.076577 0 Td 44.66967 Tz (exons ) Tj 1.387387 0 Td 13.138138 Tz (, ) Tj 0.29955 0 Td 47.297297 Tz (and ) Tj 1.024775 0 Td 42.83033 Tz (connecting ) Tj 2.743243 0 Td 42.567568 Tz (black ) Tj 1.466216 0 Td 35.735736 Tz (lines ) Tj 1.292793 0 Td 49.924925 Tz (show ) Tj 1.387387 0 Td 39.414414 Tz (the ) Tj 0.898649 0 Td 40.540541 Tz (introns ) Tj 1.655405 0 Td 21.021021 Tz (. ) Tj 0.29955 0 Td 46.421421 Tz (Check- ) Tj 2.081081 0 Td 34.159159 Tz (30 ) Tj 0.804054 0 Td 41.458125 Tz (polyploid ) Tj 2.286036 0 Td 13.138138 Tz (, ) Tj 0.331081 0 Td 38.663664 Tz (diploid ) Tj 1.655405 0 Td 26.276276 Tz (, ) Tj 0.346847 0 Td 42.417417 Tz (haploid ) Tj 1.986486 0 Td 46.421421 Tz (and ) Tj 1.024775 0 Td 47.297297 Tz (hemizygous ) Tj 2.900901 0 Td 10.510511 Tz (. ) Tj 58.843537 0 0 58.843537 0 1664.7417 Tm 5.489133 0 Td 45.317919 Tz (ered ) Tj 1.308555 0 Td 44.104046 Tz (regions ) Tj 2.124277 0 Td 48.150289 Tz (of ) Tj 0.76474 0 Td 50.982659 Tz (exon ) Tj 1.52948 0 Td 28.323699 Tz (1 ) Tj 0.492832 0 Td 50.982659 Tz (and ) Tj 1.155607 0 Td 45.317919 Tz (2 ) Tj 0.560809 0 Td 42.485549 Tz (depict ) Tj 1.767399 0 Td 42.485549 Tz (the ) Tj 0.968671 0 Td 46.16763 Tz (Agglutinin ) Tj 3.075954 0 Td 42.013487 Tz (super- ) Tj 3.432832 0 Td 43.901734 Tz (In ) Tj 0.696763 0 Td 44.104046 Tz (various ) Tj 2.073295 0 Td 50.982659 Tz (embodiments ) Tj 3.398844 0 Td 25.491329 Tz (, ) Tj 0.356879 0 Td 42.485549 Tz (the ) Tj 0.985665 0 Td 44.059088 Tz (invention ) Tj 2.583121 0 Td 31.156069 Tz (is ) Tj 0.628786 0 Td 40.007225 Tz (suitable ) Tj 2.141272 0 Td 40.597303 Tz (for ) Tj 0.900694 0 Td 47.206166 Tz (use ) Tj 63.533835 0 0 63.533835 0 1622.531788 Tm 5.083905 0 Td 41.972387 Tz (family ) Tj 1.841538 0 Td 47.218935 Tz (domains ) Tj 1.951716 0 Td 23.609467 Tz (, ) Tj 0.487929 0 Td 46.34451 Tz (and ) Tj 1.133254 0 Td 48.967784 Tz (upward ) Tj 2.077633 0 Td 41.316568 Tz (diagonal ) Tj 2.297988 0 Td 41.972387 Tz (region ) Tj 1.825799 0 Td 44.595661 Tz (of ) Tj 0.786982 0 Td 47.218935 Tz (exon ) Tj 1.448047 0 Td 41.972387 Tz (2 ) Tj 1.463787 0 Td 43.939842 Tz (with ) Tj 1.33787 0 Td 39.349112 Tz (a ) Tj 0.535148 0 Td 38.599606 Tz (variety ) Tj 1.935976 0 Td 44.595661 Tz (of ) Tj 0.755503 0 Td 38.474688 Tz (plants ) Tj 1.369349 0 Td 26.232742 Tz (, ) Tj 0.487929 0 Td 40.806487 Tz (including ) Tj 2.486864 0 Td 43.939842 Tz (both ) Tj 1.33787 0 Td 46.094675 Tz (monocotyledons ) Tj 56.122449 0 0 56.122449 0 1582.963636 Tm 5.773091 0 Td 53.454545 Tz (shows ) Tj 1.888727 0 Td 69.292929 Tz (ETX ) Tj 1.265091 0 Td 29.69697 Tz (/ ) Tj 0.213818 0 Td 73.5 Tz (MTX2 ) Tj 2.031273 0 Td 55.434343 Tz (domain ) Tj 2.049091 0 Td 11.878788 Tz (. ) Tj 0.356364 0 Td 51.078788 Tz (Black ) Tj 1.764 0 Td 51.078788 Tz (boxes ) Tj 1.799636 0 Td 38.606061 Tz (at ) Tj 0.694909 0 Td 44.545455 Tz (the ) Tj 1.069091 0 Td 49 Tz (ends ) Tj 1.461091 0 Td 56.424242 Tz (show ) Tj 2.761818 0 Td 29.69697 Tz (\( ) Tj 0.196 0 Td 31.924242 Tz (i.e. ) Tj 0.837455 0 Td 14.848485 Tz (, ) Tj 0.392 0 Td 43.555556 Tz (plants ) Tj 1.853091 0 Td 49.989899 Tz (having ) Tj 2.102545 0 Td 51.474747 Tz (one ) Tj 1.211636 0 Td 48.505051 Tz (cotyledon ) Tj 2.904364 0 Td 29.69697 Tz (\( ) Tj 0.231636 0 Td 44.545455 Tz (seed ) Tj 1.211636 0 Td 29.69697 Tz (- ) Tj 0.213818 0 Td 41.575758 Tz (leaf ) Tj 1.051273 0 Td 29.69697 Tz (\) ) Tj 0.053455 0 Td 29.69697 Tz (, ) Tj 0.498909 0 Td 50.484848 Tz (aka ) Tj 1.211636 0 Td 38.606061 Tz ( ) Tj 0.196 0 Td 77.212121 Tz (mono ) Tj 59.365079 0 0 59.365079 0 1540.286979 Tm 5.424064 0 Td 42.112299 Tz (the ) Tj 0.926471 0 Td 42.814171 Tz (untranslated ) Tj 3.234225 0 Td 44.919786 Tz (region ) Tj 1.768717 0 Td 36.497326 Tz (at ) Tj 0.623262 0 Td 39.304813 Tz (5 ) Tj 0.303209 0 Td 11.229947 Tz (' ) Tj 0.269519 0 Td 49.59893 Tz (and ) Tj 1.06123 0 Td 42.112299 Tz (3 ) Tj 0.303209 0 Td 11.229947 Tz (' ) Tj 0.269519 0 Td 47.025401 Tz (ends ) Tj 1.145455 0 Td 19.652406 Tz (. ) Tj 0.269519 0 Td 51.938503 Tz (Arrows ) Tj 2.05508 0 Td 41.059492 Tz (indicate ) Tj 2.139305 0 Td 42.112299 Tz (the ) Tj 2.05508 0 Td 41.410428 Tz (cots ) Tj 1.044385 0 Td 28.074866 Tz ( ) Tj 0.252674 0 Td 28.074866 Tz (\) ) Tj 0.387433 0 Td 50.534759 Tz (and ) Tj 1.09492 0 Td 44.217914 Tz (dicotyledons ) Tj 3.436364 0 Td 28.074866 Tz (\( ) Tj 0.185294 0 Td 29.47861 Tz (i.e. ) Tj 0.791711 0 Td 14.037433 Tz (, ) Tj 0.303209 0 Td 41.176471 Tz (plants ) Tj 1.701337 0 Td 47.259358 Tz (having ) Tj 1.886631 0 Td 51.470588 Tz (two ) Tj 1.162299 0 Td 45.481283 Tz (cotyledons ) Tj 2.661497 0 Td 28.074866 Tz (, ) Tj 61.714286 0 0 61.714286 0 1498.356337 Tm 5.217593 0 Td 40.846836 Tz (position ) Tj 2.171296 0 Td 45.910494 Tz (of ) Tj 0.729167 0 Td 39.158951 Tz (stop ) Tj 1.199074 0 Td 48.611111 Tz (codon ) Tj 1.668981 0 Td 39.158951 Tz (in ) Tj 0.664352 0 Td 40.509259 Tz (the ) Tj 0.939815 0 Td 49.511317 Tz (two ) Tj 1.134259 0 Td 37.808642 Tz (identified ) Tj 2.479167 0 Td 45.138889 Tz (mutants ) Tj 1.928241 0 Td 16.203704 Tz (. ) Tj 2.025463 0 Td 35.108025 Tz (35 ) Tj 0.842593 0 Td 45.010288 Tz (aka ) Tj 1.037037 0 Td 27.006173 Tz (" ) Tj 0.324074 0 Td 38.708848 Tz (dicots ) Tj 1.474537 0 Td 27.006173 Tz (" ) Tj 0.291667 0 Td 27.006173 Tz (\) ) Tj 0.048611 0 Td 27.006173 Tz (. ) Tj 0.388889 0 Td 57.613169 Tz (Non ) Tj 1.069444 0 Td 27.006173 Tz (- ) Tj 0.194444 0 Td 39.834105 Tz (limiting ) Tj 2.106481 0 Td 47.260802 Tz (examples ) Tj 2.49537 0 Td 45.910494 Tz (of ) Tj 0.712963 0 Td 38.708848 Tz (plants ) Tj 1.652778 0 Td 38.483796 Tz (suitable ) Tj 2.074074 0 Td 39.609053 Tz (for ) Tj 61.614907 0 0 61.614907 0 1453.719842 Tm 5.858972 0 Td 53.197805 Tz (FIG ) Tj 1.00625 0 Td 10.819892 Tz (. ) Tj 0.373286 0 Td 33.812164 Tz (2. ) Tj 0.714113 0 Td 42.07736 Tz (Predicted ) Tj 2.531855 0 Td 40.961022 Tz (protein ) Tj 2.0125 0 Td 38.470729 Tz (structure ) Tj 2.353327 0 Td 45.984543 Tz (of ) Tj 0.762802 0 Td 52.746976 Tz (Fhb1 ) Tj 1.217238 0 Td 21.639785 Tz (. ) Tj 0.438206 0 Td 50.042003 Tz (Dark ) Tj 1.476915 0 Td 43.955813 Tz (grey ) Tj 2.288407 0 Td 40.574597 Tz (the ) Tj 0.941331 0 Td 41.776807 Tz (disclosed ) Tj 2.450706 0 Td 48.935423 Tz (embodiments ) Tj 3.456956 0 Td 42.120296 Tz (include ) Tj 1.98004 0 Td 40.123768 Tz (grains ) Tj 1.687903 0 Td 27.049731 Tz (\( ) Tj 0.178528 0 Td 34.488407 Tz (e.g. ) Tj 0.892641 0 Td 13.524866 Tz (, ) Tj 0.308367 0 Td 48.148522 Tz (wheat ) Tj 1.476915 0 Td 13.524866 Tz (, ) Tj 0.324597 0 Td 42.377912 Tz (oat ) Tj 0.746573 0 Td 21.639785 Tz (, ) Tj 59.52381 0 0 59.52381 0 1415.149186 Tm 5.3928 0 Td 44.4 Tz (ribbons ) Tj 2.0664 0 Td 42.622222 Tz (represent ) Tj 2.4864 0 Td 44.8 Tz (alpha ) Tj 1.5288 0 Td 40.8 Tz (helices ) Tj 1.932 0 Td 49.466667 Tz (and ) Tj 1.092 0 Td 37.52 Tz (light ) Tj 1.3272 0 Td 44.8 Tz (grey ) Tj 1.2768 0 Td 44 Tz (ribbons ) Tj 2.0832 0 Td 53.2 Tz (show ) Tj 2.5872 0 Td 42.466667 Tz (barley ) Tj 1.4784 0 Td 28 Tz (, ) Tj 0.5208 0 Td 39.2 Tz (rice ) Tj 0.9744 0 Td 14 Tz (, ) Tj 0.4368 0 Td 49.84 Tz (maize ) Tj 1.5456 0 Td 14 Tz (, ) Tj 0.4368 0 Td 40.6 Tz (millet ) Tj 1.4952 0 Td 14 Tz (, ) Tj 0.4368 0 Td 42.933333 Tz (rye ) Tj 0.8064 0 Td 19.6 Tz (, ) Tj 0.504 0 Td 45.6 Tz (sorghum ) Tj 2.1336 0 Td 28 Tz (, ) Tj 0.504 0 Td 34.844444 Tz (triticale ) Tj 1.932 0 Td 25.2 Tz (, ) Tj 0.42 0 Td 62.3 Tz (buck ) Tj 59.257143 0 0 59.257143 0 1375.469595 Tm 5.433944 0 Td 43.595307 Tz (beta ) Tj 1.350048 0 Td 43.394407 Tz (pleated ) Tj 2.126326 0 Td 42.189007 Tz (sheets ) Tj 1.518804 0 Td 25.313404 Tz (, ) Tj 0.472517 0 Td 40.548323 Tz (respectively ) Tj 2.970106 0 Td 28.126005 Tz (. ) Tj 0.506268 0 Td 40.782707 Tz (Starting ) Tj 2.261331 0 Td 50.626808 Tz (and ) Tj 1.248795 0 Td 33.751205 Tz (last ) Tj 1.147541 0 Td 51.751848 Tz (amino ) Tj 2.835101 0 Td 50.064288 Tz (wheat ) Tj 1.53568 0 Td 14.063002 Tz (, ) Tj 0.590646 0 Td 48.282974 Tz (quinoa ) Tj 1.805689 0 Td 28.126005 Tz (\) ) Tj 0.050627 0 Td 28.126005 Tz (, ) Tj 0.675024 0 Td 49.019608 Tz (legumes ) Tj 2.565092 0 Td 28.126005 Tz (\( ) Tj 0.202507 0 Td 35.157506 Tz (e.g. ) Tj 0.928158 0 Td 14.063002 Tz (, ) Tj 0.590646 0 Td 48.165783 Tz (soybeans ) Tj 2.244455 0 Td 28.126005 Tz (, ) Tj 0.641273 0 Td 49.501768 Tz (beans ) Tj 1.434426 0 Td 25.313404 Tz (, ) Tj 0.607522 0 Td 45.704757 Tz (peas ) Tj 1.164417 0 Td 14.063002 Tz (, ) Tj 58.8 0 0 58.8 0 1329.541254 Tm 5.493197 0 Td 41.950113 Tz (acids ) Tj 1.564626 0 Td 28.344671 Tz (\( ) Tj 0.119048 0 Td 49.886621 Tz (Methionine ) Tj 3.265306 0 Td 50.075586 Tz (and ) Tj 1.156463 0 Td 49.400713 Tz (Leucine ) Tj 2.057823 0 Td 28.344671 Tz (\) ) Tj 0.442177 0 Td 48.185941 Tz (of ) Tj 0.765306 0 Td 42.517007 Tz (the ) Tj 1.020408 0 Td 42.921931 Tz (protein ) Tj 2.057823 0 Td 45.918367 Tz (chain ) Tj 1.615646 0 Td 49.603175 Tz (have ) Tj 2.5 0 Td 37.252996 Tz (alfalfa ) Tj 1.683673 0 Td 28.344671 Tz (\) ) Tj 0.102041 0 Td 28.344671 Tz (, ) Tj 0.578231 0 Td 42.517007 Tz (tubers ) Tj 1.972789 0 Td 28.344671 Tz (\( ) Tj 0.204082 0 Td 35.430839 Tz (e.g. ) Tj 0.935374 0 Td 14.172336 Tz (, ) Tj 0.510204 0 Td 44.288549 Tz (potatoes ) Tj 2.091837 0 Td 25.510204 Tz (, ) Tj 0.612245 0 Td 47.052154 Tz (sweet ) Tj 1.802721 0 Td 43.93424 Tz (potatoes ) Tj 2.07483 0 Td 25.510204 Tz (, ) Tj 0.612245 0 Td 45.351474 Tz (cassava ) Tj 1.955782 0 Td 14.172336 Tz (, ) Tj 54.285714 0 0 54.285714 0 1287 Tm 5.931579 0 Td 54.495614 Tz (been ) Tj 1.528947 0 Td 56.030702 Tz (numbered ) Tj 2.8 0 Td 21.491228 Tz (. ) Tj 65.714286 0 0 65.714286 0 1287.4677 Tm 18.915217 0 Td 35.507246 Tz (40 ) Tj 0.806522 0 Td 44.806763 Tz (yam ) Tj 1.05 0 Td 25.362319 Tz (\) ) Tj 0.076087 0 Td 25.362319 Tz (, ) Tj 0.441304 0 Td 45.652174 Tz (and ) Tj 1.065217 0 Td 38.043478 Tz (the ) Tj 0.943478 0 Td 34.873188 Tz (like ) Tj 0.897826 0 Td 10.144928 Tz (. ) Tj 0.35 0 Td 39.311594 Tz (In ) Tj 0.715217 0 Td 36.956522 Tz (certain ) Tj 1.780435 0 Td 38.888889 Tz (preferred ) Tj 2.358696 0 Td 45.88274 Tz (embodiments ) Tj 3.302174 0 Td 38.043478 Tz (the ) Tj 59.880952 0 0 59.880952 0 1249.886228 Tm 6.028628 0 Td 54.738237 Tz (FIG ) Tj 1.035388 0 Td 11.133201 Tz (. ) Tj 0.350696 0 Td 34.791252 Tz (3. ) Tj 0.718091 0 Td 41.351889 Tz (Clustal ) Tj 2.003976 0 Td 59.562624 Tz (Omega ) Tj 2.054076 0 Td 48.011928 Tz (gene ) Tj 1.436183 0 Td 46.620278 Tz (sequence ) Tj 2.50497 0 Td 45.769825 Tz (alignment ) Tj 2.738767 0 Td 47.316103 Tz (of ) Tj 0.751491 0 Td 41.749503 Tz (the ) Tj 2.020676 0 Td 41.192843 Tz (plant ) Tj 1.436183 0 Td 30.616302 Tz (is ) Tj 0.584493 0 Td 41.749503 Tz (a ) Tj 0.450895 0 Td 40.079523 Tz (grain ) Tj 1.219085 0 Td 27.833002 Tz (, ) Tj 0.367396 0 Td 50.099404 Tz (most ) Tj 1.386083 0 Td 42.584493 Tz (preferably ) Tj 2.738767 0 Td 49.542744 Tz (wheat ) Tj 1.66998 0 Td 43.141153 Tz (or ) Tj 0.667992 0 Td 42.213386 Tz (barley ) Tj 1.469583 0 Td 27.833002 Tz (, ) Tj 0.400795 0 Td 43.141153 Tz (or ) Tj 0.684692 0 Td 41.749503 Tz (a ) Tj 0.434195 0 Td 49.542744 Tz (wheat ) Tj 60.095238 0 0 60.095238 0 1205.05561 Tm 5.341521 0 Td 48.071844 Tz (mutant ) Tj 1.930269 0 Td 40.213946 Tz (plants ) Tj 1.697306 0 Td 38.827258 Tz (as ) Tj 0.698891 0 Td 50.960777 Tz (compared ) Tj 2.62916 0 Td 38.827258 Tz (to ) Tj 0.68225 0 Td 46.454041 Tz (wild ) Tj 1.29794 0 Td 44.37401 Tz (type ) Tj 1.264659 0 Td 38.210953 Tz (resistant ) Tj 2.279715 0 Td 37.717908 Tz (lines ) Tj 1.214739 0 Td 11.093502 Tz (. ) Tj 0.299525 0 Td 52.694136 Tz (The ) Tj 2.213154 0 Td 45.760697 Tz (or ) Tj 0.732171 0 Td 42.987322 Tz (barley ) Tj 1.763867 0 Td 38.827258 Tz (cultivar ) Tj 1.847068 0 Td 24.96038 Tz (. ) Tj 58.714286 0 0 58.714286 0 1163.974359 Tm 5.501217 0 Td 73.803731 Tz (G ) Tj 0.459854 0 Td 56.772101 Tz (> ) Tj 0.357664 0 Td 73.803731 Tz (A ) Tj 0.63017 0 Td 46.048482 Tz (mutations ) Tj 2.725061 0 Td 49.675588 Tz (have ) Tj 1.413625 0 Td 50.385239 Tz (been ) Tj 1.413625 0 Td 44.127405 Tz (highlighted ) Tj 3.150852 0 Td 38.321168 Tz (in ) Tj 0.681265 0 Td 42.579075 Tz (grey ) Tj 1.090024 0 Td 19.870235 Tz (. ) Tj 60 0 0 60 0 1165.759791 Tm 22.233333 0 Td 43.055556 Tz (In ) Tj 0.666667 0 Td 42.592593 Tz (preferred ) Tj 2.466667 0 Td 50.505051 Tz (embodiments ) Tj 3.316667 0 Td 25 Tz (, ) Tj 0.35 0 Td 41.666667 Tz (the ) Tj 0.95 0 Td 42.063492 Tz (disease ) Tj 1.966667 0 Td 30.555556 Tz (is ) Tj 0.583333 0 Td 43.055556 Tz (fungal ) Tj 1.75 0 Td 40.277778 Tz (in ) Tj 0.65 0 Td 41.203704 Tz (origin ) Tj 1.533333 0 Td 11.111111 Tz (. ) Tj 59.206349 0 0 59.206349 0 1124.442201 Tm 6.097319 0 Td 55.36193 Tz (FIG ) Tj 1.047185 0 Td 11.260054 Tz (. ) Tj 0.354692 0 Td 35.187668 Tz (4. ) Tj 0.709383 0 Td 41.823056 Tz (Clustal ) Tj 2.02681 0 Td 60.241287 Tz (Omega ) Tj 2.06059 0 Td 42.627346 Tz (protein ) Tj 2.0437 0 Td 46.291332 Tz (alignment ) Tj 2.753083 0 Td 47.855228 Tz (of ) Tj 0.760054 0 Td 42.225201 Tz (the ) Tj 0.996515 0 Td 48.793566 Tz (mutant ) Tj 3.073995 0 Td 39.410188 Tz (In ) Tj 1.047185 0 Td 40.536193 Tz (particular ) Tj 2.972654 0 Td 43.163539 Tz (preferred ) Tj 2.871314 0 Td 51.693883 Tz (embodiments ) Tj 3.378016 0 Td 28.150134 Tz (, ) Tj 0.743164 0 Td 43.163539 Tz (the ) Tj 1.317426 0 Td 43.431635 Tz (disease ) Tj 2.398391 0 Td 33.780161 Tz (is ) Tj 63.311688 0 0 63.311688 0 1085.024455 Tm 5.070154 0 Td 38.609687 Tz (plants ) Tj 1.769026 0 Td 47.384615 Tz (compared ) Tj 2.685128 0 Td 34.222222 Tz (to ) Tj 0.789744 0 Td 42.119658 Tz (wild ) Tj 1.184615 0 Td 50.675214 Tz (type ) Tj 1.579487 0 Td 36.854701 Tz (protein ) Tj 1.579487 0 Td 31.589744 Tz (. ) Tj 0.552821 0 Td 43.435897 Tz (Tryptophan ) Tj 2.827282 0 Td 26.324786 Tz (> ) Tj 0.284308 0 Td 38.82906 Tz (stop ) Tj 1.310974 0 Td 34.222222 Tz (45 ) Tj 0.821333 0 Td 47.384615 Tz (Fusarium ) Tj 2.653538 0 Td 50.017094 Tz (Head ) Tj 1.611077 0 Td 39.487179 Tz (Blight ) Tj 1.800615 0 Td 43.623932 Tz (Disease ) Tj 2.179692 0 Td 26.324786 Tz (\( ) Tj 0.189538 0 Td 61.424501 Tz (FHB ) Tj 1.20041 0 Td 21.059829 Tz (\) ) Tj 0.189538 0 Td 5.264957 Tz (. ) Tj 0.442256 0 Td 52.649573 Tz (More ) Tj 1.611077 0 Td 40.364672 Tz (generally ) Tj 2.163897 0 Td 26.324786 Tz (, ) Tj 62.936508 0 0 62.936508 0 1040.392611 Tm 5.132156 0 Td 48.196721 Tz (codon ) Tj 1.684237 0 Td 42.959227 Tz (mutations ) Tj 2.605801 0 Td 38.398487 Tz (in ) Tj 0.699117 0 Td 39.722573 Tz (the ) Tj 0.969231 0 Td 44.262295 Tz (mutants ) Tj 2.145019 0 Td 46.343001 Tz (have ) Tj 1.366456 0 Td 47.005044 Tz (been ) Tj 1.366456 0 Td 41.16703 Tz (highlighted ) Tj 2.971248 0 Td 38.398487 Tz (in ) Tj 1.668348 0 Td 46.674023 Tz (enhanced ) Tj 2.351576 0 Td 38.928121 Tz (resistance ) Tj 2.478689 0 Td 37.074401 Tz (to ) Tj 0.619672 0 Td 45.901639 Tz (any ) Tj 0.98512 0 Td 41.046658 Tz (fungal ) Tj 1.63657 0 Td 45.349937 Tz (pathogen ) Tj 2.319798 0 Td 29.129887 Tz (is ) Tj 0.524338 0 Td 43.69483 Tz (contemplated ) Tj 3.161917 0 Td 26.481715 Tz (, ) Tj 42.857143 0 0 42.857143 0 1001.373134 Tm 7.513333 0 Td 58.333333 Tz (grey ) Tj 1.47 0 Td 27.222222 Tz (. ) Tj 60.714286 0 0 60.714286 0 1002.680662 Tm 21.345882 0 Td 42.701525 Tz (including ) Tj 2.503529 0 Td 42.54902 Tz (fungal ) Tj 1.729412 0 Td 40.627451 Tz (pests ) Tj 1.449412 0 Td 45.980392 Tz (such ) Tj 1.284706 0 Td 39.803922 Tz (as ) Tj 0.708235 0 Td 41.176471 Tz (species ) Tj 1.943529 0 Td 46.666667 Tz (of ) Tj 0.658824 0 Td 47.352941 Tz (Fusarium ) Tj 2.338824 0 Td 24.705882 Tz (, ) Tj 0.543529 0 Td 44.379085 Tz (Sclero ) Tj 61.428571 0 0 61.428571 0 956.912185 Tm 5.876744 0 Td 53.359173 Tz (FIG ) Tj 1.009302 0 Td 10.852713 Tz (. ) Tj 0.406977 0 Td 33.914729 Tz (5. ) Tj 0.765116 0 Td 44.573643 Tz (Disease ) Tj 2.197674 0 Td 39.341085 Tz (severity ) Tj 2.213953 0 Td 50.193798 Tz (on ) Tj 0.895349 0 Td 40.697674 Tz (the ) Tj 1.074419 0 Td 40.697674 Tz (spikes ) Tj 1.806977 0 Td 44.767442 Tz (of ) Tj 0.781395 0 Td 39.793282 Tz (plants ) Tj 1.75814 0 Td 45.445736 Tz (with ) Tj 2.327907 0 Td 35.813953 Tz (tinia ) Tj 1.106977 0 Td 13.565891 Tz (, ) Tj 0.439535 0 Td 39.341085 Tz (Botrytis ) Tj 1.937209 0 Td 35.271318 Tz (, ) Tj 0.390698 0 Td 46.937984 Tz (Cercospora ) Tj 2.783721 0 Td 24.418605 Tz (, ) Tj 0.504651 0 Td 42.054264 Tz (Gibberella ) Tj 2.490698 0 Td 24.418605 Tz (, ) Tj 0.52093 0 Td 48.837209 Tz (Oidium ) Tj 1.790698 0 Td 13.565891 Tz (, ) Tj 0.52093 0 Td 50.775194 Tz (Phytoph ) Tj 60 0 0 60 0 914.206369 Tm 5.366667 0 Td 52.777778 Tz (non ) Tj 0.966667 0 Td 25 Tz (- ) Tj 0.216667 0 Td 43.333333 Tz (sense ) Tj 1.466667 0 Td 45.061728 Tz (mutations ) Tj 2.633333 0 Td 38.888889 Tz (as ) Tj 0.666667 0 Td 51.041667 Tz (compared ) Tj 2.6 0 Td 46.527778 Tz (with ) Tj 1.266667 0 Td 38.271605 Tz (resistant ) Tj 2.25 0 Td 49.074074 Tz (and ) Tj 1.066667 0 Td 43.650794 Tz (suscep- ) Tj 3.1 0 Td 41.666667 Tz (thora ) Tj 1.316667 0 Td 22.222222 Tz (, ) Tj 0.583333 0 Td 46.527778 Tz (Sephoria ) Tj 2.2 0 Td 27.777778 Tz (, ) Tj 0.733333 0 Td 36.574074 Tz (Verticillium ) Tj 2.783333 0 Td 22.222222 Tz (, ) Tj 0.583333 0 Td 41.388889 Tz (Alternaria ) Tj 2.583333 0 Td 22.222222 Tz (, ) Tj 0.616667 0 Td 44.212963 Tz (Cladisporium ) Tj 3.383333 0 Td 27.777778 Tz (, ) Tj 65.714286 0 0 65.714286 0 871.364655 Tm 4.9 0 Td 33.478261 Tz (tible ) Tj 1.126087 0 Td 41.213768 Tz (near ) Tj 1.11087 0 Td 38.677536 Tz (isogenic ) Tj 2.023913 0 Td 34.492754 Tz (lines ) Tj 1.202174 0 Td 30.434783 Tz (\( ) Tj 0.136957 0 Td 52.626812 Tz (NILs ) Tj 1.171739 0 Td 30.434783 Tz (\) ) Tj 0.334783 0 Td 36.775362 Tz (as ) Tj 0.593478 0 Td 38.677536 Tz (controls ) Tj 1.826087 0 Td 17.753623 Tz (. ) Tj 0.273913 0 Td 43.623188 Tz (Black ) Tj 1.445652 0 Td 37.40942 Tz (dots ) Tj 1.065217 0 Td 45.652174 Tz (on ) Tj 0.669565 0 Td 38.043478 Tz (the ) Tj 1.05 0 Td 34.23913 Tz (50 ) Tj 0.776087 0 Td 40.118577 Tz (Rhizoctonia ) Tj 2.708696 0 Td 22.826087 Tz (, ) Tj 0.502174 0 Td 38.360507 Tz (Ustilago ) Tj 1.871739 0 Td 25.362319 Tz (, ) Tj 0.441304 0 Td 39.311594 Tz (or ) Tj 0.715217 0 Td 41.847826 Tz (Puccinia ) Tj 2.084783 0 Td 10.144928 Tz (. ) Tj 0.380435 0 Td 39.311594 Tz (In ) Tj 0.730435 0 Td 38.607085 Tz (preferred ) Tj 2.434783 0 Td 50.301932 Tz (embodi ) Tj 57.755102 0 0 57.755102 0 830.630081 Tm 5.59258 0 Td 43.286219 Tz (spikes ) Tj 1.835336 0 Td 54.829211 Tz (show ) Tj 1.558304 0 Td 43.286219 Tz (the ) Tj 1.00424 0 Td 43.863369 Tz (point ) Tj 1.558304 0 Td 49.057715 Tz (of ) Tj 0.761837 0 Td 43.810901 Tz (inoculation ) Tj 2.943463 0 Td 11.542992 Tz (. ) Tj 58.961039 0 0 58.961039 0 835.518325 Tm 21.963656 0 Td 49.185022 Tz (ments ) Tj 1.492511 0 Td 22.613803 Tz (, ) Tj 0.424009 0 Td 42.400881 Tz (targeted ) Tj 2.272687 0 Td 44.285365 Tz (fungal ) Tj 1.848678 0 Td 48.407673 Tz (pathogen ) Tj 2.577974 0 Td 31.093979 Tz (is ) Tj 0.661454 0 Td 42.400881 Tz (a ) Tj 0.525771 0 Td 42.400881 Tz (species ) Tj 2.052203 0 Td 48.054332 Tz (of ) Tj 0.729295 0 Td 46.99431 Tz (Fusarium ) Tj 2.493172 0 Td 25.440529 Tz (, ) Tj 61.6 0 0 61.6 0 790.275552 Tm 5.86039 0 Td 53.210678 Tz (FIG ) Tj 1.006494 0 Td 10.822511 Tz (. ) Tj 0.38961 0 Td 32.467532 Tz (6. ) Tj 0.714286 0 Td 39.231602 Tz (Effect ) Tj 1.704545 0 Td 45.995671 Tz (of ) Tj 0.746753 0 Td 41.486291 Tz (the ) Tj 1.022727 0 Td 39.231602 Tz (isolated ) Tj 2.142857 0 Td 40.970934 Tz (protein ) Tj 1.996753 0 Td 50.054113 Tz (on ) Tj 0.86039 0 Td 40.584416 Tz (the ) Tj 1.038961 0 Td 43.290043 Tz (spread ) Tj 1.834416 0 Td 45.995671 Tz (of ) Tj 1.737013 0 Td 34.496753 Tz (e.g. ) Tj 0.892857 0 Td 13.528139 Tz (, ) Tj 0.308442 0 Td 40.584416 Tz (a ) Tj 0.470779 0 Td 40.584416 Tz (species ) Tj 1.931818 0 Td 40.246212 Tz (selected ) Tj 2.126623 0 Td 48.701299 Tz (from ) Tj 1.331169 0 Td 37.878788 Tz (F. ) Tj 0.714286 0 Td 46.296296 Tz (avenaceum ) Tj 2.711039 0 Td 35.17316 Tz (, ) Tj 0.25974 0 Td 35.17316 Tz (F. ) Tj 0.665584 0 Td 45.995671 Tz (bubigeum ) Tj 2.288961 0 Td 27.056277 Tz (, ) Tj 0.405844 0 Td 35.17316 Tz (F. ) Tj 60 0 0 60 0 752.585253 Tm 5.4 0 Td 42.592593 Tz (fungal ) Tj 1.766667 0 Td 45.634921 Tz (mycelia ) Tj 1.95 0 Td 27.777778 Tz (. ) Tj 59.642857 0 0 59.642857 0 753.814446 Tm 21.746108 0 Td 52.045908 Tz (culmorum ) Tj 2.531737 0 Td 13.972056 Tz (, ) Tj 0.268263 0 Td 36.327345 Tz (F. ) Tj 0.603593 0 Td 48.775177 Tz (graminearum ) Tj 3.37006 0 Td 25.149701 Tz (, ) Tj 0.352096 0 Td 36.327345 Tz (F. ) Tj 0.637126 0 Td 43.186355 Tz (langsethiae ) Tj 2.783234 0 Td 27.944112 Tz (, ) Tj 0.368862 0 Td 36.327345 Tz (F. ) Tj 0.637126 0 Td 48.12597 Tz (oxysporum ) Tj 2.749701 0 Td 19.560878 Tz (, ) Tj 0.268263 0 Td 39.121756 Tz (F. ) Tj 62.207792 0 0 62.207792 0 709.731613 Tm 20.753027 0 Td 50.904662 Tz (poae ) Tj 1.237787 0 Td 13.395964 Tz (, ) Tj 0.401879 0 Td 34.829506 Tz (F. ) Tj 0.739457 0 Td 40.355341 Tz (sporotrichioides ) Tj 3.841962 0 Td 24.112735 Tz (, ) Tj 0.482255 0 Td 36.169102 Tz (F. ) Tj 0.739457 0 Td 38.580376 Tz (tricinctum ) Tj 2.443424 0 Td 24.112735 Tz (, ) Tj 0.434029 0 Td 34.829506 Tz (F. ) Tj 0.739457 0 Td 36.258409 Tz (verticillioides ) Tj 3.263257 0 Td 24.112735 Tz (, ) Tj 52.380952 0 0 52.380952 0 672.673096 Tm 7.846364 0 Td 71.590909 Tz (DETAILED ) Tj 3.703636 0 Td 70.289256 Tz (DESCRIPTION ) Tj 4.887273 0 Td 71.590909 Tz (OF ) Tj 1.145455 0 Td 74.242424 Tz (PREFERRED ) Tj 6.147273 0 Td 42.954545 Tz (55 ) Tj 1.011818 0 Td 57.272727 Tz (and ) Tj 1.221818 0 Td 42.954545 Tz (F. ) Tj 0.820909 0 Td 49.848485 Tz (virguliforme ) Tj 3.417273 0 Td 35 Tz (. ) Tj 47.142857 0 0 47.142857 0 631 Tm 13.469697 0 Td 87.419651 Tz (EMBODIMENTS ) Tj 56.785714 0 0 56.785714 0 627.887742 Tm 23.491824 0 Td 45.492662 Tz (In ) Tj 0.810063 0 Td 55.765199 Tz (some ) Tj 1.602516 0 Td 53.097008 Tz (embodiments ) Tj 3.486792 0 Td 26.415094 Tz (, ) Tj 0.440252 0 Td 44.025157 Tz (the ) Tj 1.038994 0 Td 45.981831 Tz (invention ) Tj 2.72956 0 Td 51.496093 Tz (encompasses ) Tj 3.645283 0 Td 59.433962 Tz (poly ) Tj 57.142857 0 0 57.142857 0 584.774398 Tm 22.68 0 Td 44.84375 Tz (peptides ) Tj 2.345 0 Td 52.5 Tz (and ) Tj 1.085 0 Td 44.583333 Tz (nucleic ) Tj 2.065 0 Td 43.166667 Tz (acids ) Tj 1.4875 0 Td 40.104167 Tz (that ) Tj 1.1375 0 Td 42.777778 Tz (are ) Tj 0.945 0 Td 45.694444 Tz (not ) Tj 0.9975 0 Td 41.157407 Tz (identical ) Tj 2.3975 0 Td 39.375 Tz (to ) Tj 0.6825 0 Td 50.555556 Tz (any ) Tj 1.1025 0 Td 48.125 Tz (of ) Tj 0.665 0 Td 44.722222 Tz (the ) Tj 62.142857 0 0 62.142857 0 542.019645 Tm 5.809195 0 Td 40.229885 Tz (In ) Tj 0.756322 0 Td 51.628352 Tz (some ) Tj 1.512644 0 Td 49.251132 Tz (embodiments ) Tj 3.218391 0 Td 24.137931 Tz (, ) Tj 0.418391 0 Td 40.229885 Tz (the ) Tj 0.997701 0 Td 42.01788 Tz (invention ) Tj 2.510345 0 Td 42.576628 Tz (provides ) Tj 2.317241 0 Td 39.894636 Tz (proteins ) Tj 1.97931 0 Td 13.409962 Tz (, ) Tj 1.351724 0 Td 37.547893 Tz (explicitly ) Tj 2.429885 0 Td 41.123883 Tz (disclosed ) Tj 2.365517 0 Td 41.83908 Tz (nucleotide ) Tj 2.687356 0 Td 40.229885 Tz (or ) Tj 0.643678 0 Td 48.812261 Tz (amino ) Tj 1.657471 0 Td 41.570881 Tz (acid ) Tj 1.174713 0 Td 44.997871 Tz (sequences ) Tj 2.413793 0 Td 18.773946 Tz (, ) Tj 0.289655 0 Td 42.911877 Tz (but ) Tj 58.231293 0 0 58.231293 0 503.235984 Tm 5.529673 0 Td 43.75 Tz (nucleic ) Tj 2.198131 0 Td 42.359813 Tz (acids ) Tj 1.339486 0 Td 14.310748 Tz (, ) Tj 0.463668 0 Td 50.564642 Tz (and ) Tj 1.236449 0 Td 43.341121 Tz (nucleic ) Tj 2.198131 0 Td 43.64778 Tz (acid ) Tj 1.391005 0 Td 42.359813 Tz (constructs ) Tj 2.575935 0 Td 22.897196 Tz (, ) Tj 0.480841 0 Td 47.225467 Tz (plasmids ) Tj 2.627453 0 Td 51.518692 Tz (and ) Tj 2.232477 0 Td 42.932243 Tz (instead ) Tj 1.992056 0 Td 61.05919 Tz (may ) Tj 1.30514 0 Td 50.087617 Tz (be ) Tj 0.807126 0 Td 46.50993 Tz (only ) Tj 1.339486 0 Td 28.621495 Tz ( ) Tj 0.360631 0 Td 40.290259 Tz (substantially ) Tj 3.365888 0 Td 42.29621 Tz (identical ) Tj 2.301168 0 Td 28.621495 Tz ( ) Tj 0.377804 0 Td 38.639019 Tz (to ) Tj 0.704089 0 Td 42.932243 Tz (a ) Tj 0.463668 0 Td 44.204309 Tz (reference ) Tj 61.428571 0 0 61.428571 0 460.309198 Tm 5.24186 0 Td 41.472868 Tz (vectors ) Tj 2.067442 0 Td 43.410853 Tz (capable ) Tj 2.132558 0 Td 46.124031 Tz (of ) Tj 0.797674 0 Td 46.425495 Tz (improving ) Tj 2.8 0 Td 40.697674 Tz (the ) Tj 1.05814 0 Td 41.085271 Tz (disease ) Tj 2.018605 0 Td 39.883721 Tz (resistance ) Tj 2.702326 0 Td 46.124031 Tz (of ) Tj 0.797674 0 Td 40.697674 Tz (a ) Tj 0.651163 0 Td 35.271318 Tz (60 ) Tj 0.862791 0 Td 44.089147 Tz (sequence ) Tj 2.213953 0 Td 18.992248 Tz (, ) Tj 0.439535 0 Td 33.914729 Tz (e.g. ) Tj 0.895349 0 Td 13.565891 Tz (, ) Tj 0.406977 0 Td 47.932817 Tz (one ) Tj 1.172093 0 Td 44.767442 Tz (of ) Tj 0.765116 0 Td 40.697674 Tz (the ) Tj 1.05814 0 Td 44.61671 Tz (sequences ) Tj 2.734884 0 Td 37.984496 Tz (explicitly ) Tj 2.588372 0 Td 42.807924 Tz (described ) Tj 62.597403 0 0 62.597403 0 416.962017 Tm 5.143983 0 Td 41.53527 Tz (plant ) Tj 1.198133 0 Td 26.625173 Tz (. ) Tj 0.335477 0 Td 53.250346 Tz (As ) Tj 0.894606 0 Td 45.262794 Tz (used ) Tj 1.309959 0 Td 39.050254 Tz (herein ) Tj 1.46971 0 Td 23.962656 Tz (, ) Tj 0.399378 0 Td 39.937759 Tz (the ) Tj 0.942531 0 Td 45.928423 Tz (term ) Tj 1.341909 0 Td 29.28769 Tz ( ) Tj 0.303527 0 Td 41.839557 Tz (capable ) Tj 2.012863 0 Td 43.931535 Tz (of ) Tj 0.71888 0 Td 45.558629 Tz (improving ) Tj 2.699793 0 Td 39.937759 Tz (the ) Tj 1.932988 0 Td 39.937759 Tz (herein ) Tj 1.53361 0 Td 18.637621 Tz (. ) Tj 0.383402 0 Td 53.250346 Tz (As ) Tj 0.990456 0 Td 42.896112 Tz (explained ) Tj 2.619917 0 Td 44.73029 Tz (below ) Tj 1.437759 0 Td 23.962656 Tz (, ) Tj 0.447303 0 Td 41.002766 Tz (these ) Tj 1.581535 0 Td 38.094478 Tz (substantially ) Tj 3.306846 0 Td 38.162748 Tz (identical ) Tj 59.387755 0 0 59.387755 0 376.294118 Tm 5.438832 0 Td 42.898053 Tz (disease ) Tj 2.087973 0 Td 41.254296 Tz (resistance ) Tj 2.778351 0 Td 47.709049 Tz (of ) Tj 0.808247 0 Td 42.09622 Tz (a ) Tj 0.606186 0 Td 44.902635 Tz (plant ) Tj 1.22921 0 Td 33.676976 Tz ( ) Tj 0.538832 0 Td 44.902635 Tz (denotes ) Tj 2.189003 0 Td 39.289805 Tz (that ) Tj 1.22921 0 Td 42.09622 Tz (the ) Tj 1.043986 0 Td 42.898053 Tz (protein ) Tj 2.087973 0 Td 43.499427 Tz (or ) Tj 1.78488 0 Td 41.043814 Tz (variants ) Tj 2.172165 0 Td 41.160748 Tz (are ) Tj 0.942955 0 Td 39.289805 Tz (specifically ) Tj 3.030928 0 Td 46.907216 Tz (covered ) Tj 2.138488 0 Td 50.515464 Tz (by ) Tj 0.791409 0 Td 42.09622 Tz (the ) Tj 0.926117 0 Td 46.0252 Tz (terms ) Tj 1.582818 0 Td 16.838488 Tz ( ) Tj 0.151546 0 Td 55.42669 Tz (Fhbl ) Tj 1.565979 0 Td 42.898053 Tz (nucleic ) Tj 56.581633 0 0 56.581633 0 336.628401 Tm 5.690893 0 Td 45.025549 Tz (nucleic ) Tj 2.138503 0 Td 45.656748 Tz (acid ) Tj 1.307845 0 Td 41.974752 Tz (will ) Tj 1.060415 0 Td 14.727983 Tz (, ) Tj 0.371145 0 Td 38.292756 Tz (at ) Tj 0.68927 0 Td 39.470995 Tz (least ) Tj 1.413886 0 Td 59.648332 Tz (when ) Tj 1.643643 0 Td 45.446348 Tz (present ) Tj 2.156177 0 Td 41.238353 Tz (in ) Tj 0.724617 0 Td 42.500751 Tz (certain ) Tj 2.014788 0 Td 44.920349 Tz (contexts ) Tj 2.17385 0 Td 23.564773 Tz (, ) Tj 1.590622 0 Td 42.711151 Tz (acid ) Tj 1.042741 0 Td 35.34716 Tz ( ) Tj 0.565555 0 Td 29.455966 Tz (\( ) Tj 0.212083 0 Td 45.656748 Tz (or ) Tj 0.812985 0 Td 17.67358 Tz ( ) Tj 0.159062 0 Td 58.175534 Tz (Fhb1 ) Tj 1.732011 0 Td 46.287947 Tz (polynucleotide ) Tj 3.994229 0 Td 29.455966 Tz ( ) Tj 0.24743 0 Td 29.455966 Tz (\) ) Tj 0.477187 0 Td 52.038874 Tz (and ) Tj 1.219477 0 Td 23.564773 Tz ( ) Tj 0.300451 0 Td 62.593928 Tz (FHB1 ) Tj 1.838052 0 Td 42.921551 Tz (protein ) Tj 1.979441 0 Td 29.455966 Tz ( ) Tj 0.477187 0 Td 29.455966 Tz (\( ) Tj 0.212083 0 Td 45.656748 Tz (or ) Tj 60.761905 0 0 60.761905 0 296.641144 Tm 5.299373 0 Td 44.670846 Tz (provide ) Tj 2.139498 0 Td 52.801724 Tz (some ) Tj 1.514107 0 Td 49.373041 Tz (improvement ) Tj 3.489028 0 Td 45.944357 Tz (with ) Tj 1.333072 0 Td 41.144201 Tz (respect ) Tj 1.974922 0 Td 37.029781 Tz (to ) Tj 0.691223 0 Td 40.321317 Tz (resistance ) Tj 2.666144 0 Td 37.029781 Tz (to ) Tj 0.724138 0 Td 41.144201 Tz (a ) Tj 1.481191 0 Td 30.172414 Tz ( ) Tj 0.378527 0 Td 55.544671 Tz (FHB1 ) Tj 1.596395 0 Td 45.3833 Tz (polypeptide ) Tj 2.97884 0 Td 30.172414 Tz (" ) Tj 0.296238 0 Td 30.172414 Tz (\) ) Tj 0.131661 0 Td 30.172414 Tz (. ) Tj 62.571429 0 0 62.571429 0 253.017845 Tm 5.130137 0 Td 40.334855 Tz (disease ) Tj 1.710046 0 Td 26.636225 Tz (. ) Tj 0.383562 0 Td 48.70624 Tz (Whether ) Tj 2.237443 0 Td 39.421613 Tz (there ) Tj 1.438356 0 Td 27.968037 Tz (is ) Tj 0.559361 0 Td 38.17859 Tz (actual ) Tj 1.6621 0 Td 47.46091 Tz (improvement ) Tj 3.356164 0 Td 37.290715 Tz (in ) Tj 0.655251 0 Td 45.281583 Tz (any ) Tj 1.054795 0 Td 44.216134 Tz (given ) Tj 1.710046 0 Td 33.295282 Tz (65 ) Tj 1.422374 0 Td 43.378995 Tz (Nucleic ) Tj 2.237443 0 Td 40.487062 Tz (acids ) Tj 1.598174 0 Td 42.61796 Tz (or ) Tj 0.894977 0 Td 39.288432 Tz (proteins ) Tj 2.317352 0 Td 34.627093 Tz (" ) Tj 0.303653 0 Td 44.482496 Tz (comprising ) Tj 2.636986 0 Td 34.627093 Tz ( ) Tj 0.623288 0 Td 42.61796 Tz (a ) Tj 0.639269 0 Td 41.552511 Tz (nucleotide ) Tj 59.571429 0 0 59.571429 0 212.381748 Tm 5.422062 0 Td 45.163869 Tz (context ) Tj 1.81295 0 Td 22.382094 Tz (, ) Tj 0.352518 0 Td 49.427125 Tz (and ) Tj 1.040767 0 Td 41.966427 Tz (the ) Tj 0.940048 0 Td 41.966427 Tz (extent ) Tj 1.678657 0 Td 47.56195 Tz (of ) Tj 0.688249 0 Td 51.122738 Tz (improvement ) Tj 3.306954 0 Td 27.977618 Tz (, ) Tj 0.352518 0 Td 47.56195 Tz (can ) Tj 1.007194 0 Td 46.16307 Tz (vary ) Tj 1.275779 0 Td 48.183675 Tz (depending ) Tj 3.894484 0 Td 46.86251 Tz (sequence ) Tj 2.601918 0 Td 43.365308 Tz (or ) Tj 0.856115 0 Td 50.919265 Tz (amino ) Tj 1.896882 0 Td 42.665867 Tz (acid ) Tj 1.376499 0 Td 47.21223 Tz (sequence ) Tj 2.601918 0 Td 52.597922 Tz (means ) Tj 1.930456 0 Td 38.469225 Tz (that ) Tj 1.258993 0 Td 41.966427 Tz (the ) Tj 1.107914 0 Td 39.168665 Tz (entire ) Tj 58.116883 0 0 58.116883 0 171.540717 Tm 5.523352 0 Td 53.77095 Tz (upon ) Tj 1.634637 0 Td 43.01676 Tz (the ) Tj 1.135642 0 Td 41.296089 Tz (particular ) Tj 2.804693 0 Td 45.884544 Tz (plant ) Tj 1.273296 0 Td 28.67784 Tz (, ) Tj 0.550615 0 Td 39.193048 Tz (strain ) Tj 1.755084 0 Td 44.450652 Tz (or ) Tj 0.877542 0 Td 41.224395 Tz (cultivar ) Tj 1.927151 0 Td 25.810056 Tz (, ) Tj 0.516201 0 Td 43.01676 Tz (the ) Tj 1.135642 0 Td 43.426443 Tz (genetic ) Tj 3.18324 0 Td 48.035382 Tz (sequence ) Tj 2.494972 0 Td 32.979516 Tz (is ) Tj 0.585028 0 Td 43.01676 Tz (present ) Tj 1.892737 0 Td 14.33892 Tz (, ) Tj 0.292514 0 Td 44.928616 Tz (but ) Tj 0.980782 0 Td 61.179392 Tz (may ) Tj 1.290503 0 Td 44.24581 Tz (include ) Tj 2.047598 0 Td 50.664184 Tz (one ) Tj 1.101229 0 Td 43.01676 Tz (or ) Tj 0.671061 0 Td 54.487896 Tz (more ) Tj 1.496983 0 Td 42.443203 Tz (additional ) Tj ET Q endstream endobj 177 0 obj << /Length 1 >> stream q endstream endobj 178 0 obj << /Length 58555 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 58.571429 0 0 58.571429 0 2967 Tm 12.992683 0 Td 59.756098 Tz (9 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 33.502778 0 Td 71.296296 Tz (10 ) Tj 53.690476 0 0 53.690476 0 2916.677786 Tm 5.997339 0 Td 47.691998 Tz (nucleotides ) Tj 3.576053 0 Td 48.115299 Tz (or ) Tj 0.98714 0 Td 55.875831 Tz (amino ) Tj 2.123282 0 Td 45.94235 Tz (acids ) Tj 1.825277 0 Td 55.875831 Tz (on ) Tj 1.061641 0 Td 46.563193 Tz (the ) Tj 1.266519 0 Td 46.563193 Tz (3 ) Tj 0.335255 0 Td 12.416851 Tz (' ) Tj 0.521508 0 Td 48.115299 Tz (or ) Tj 0.98714 0 Td 43.45898 Tz (5 ) Tj 0.335255 0 Td 12.416851 Tz (' ) Tj 0.502882 0 Td 55.875831 Tz (end ) Tj 1.396896 0 Td 52.771619 Tz (of ) Tj 0.949889 0 Td 47.597931 Tz (the ) Tj 2.961419 0 Td 83.813747 Tz (A ) Tj 0.67051 0 Td 49.223947 Tz (polynucleotide ) Tj 4.37694 0 Td 52.383592 Tz (sequence ) Tj 2.737916 0 Td 34.146341 Tz (is ) Tj 0.67051 0 Td 18.625277 Tz ( ) Tj 0.167627 0 Td 51.219512 Tz (heterologous ) Tj 3.911308 0 Td 38.802661 Tz (to ) Tj 0.67051 0 Td 31.042129 Tz ( ) Tj 0.409756 0 Td 46.563193 Tz (a ) Tj 0.521508 0 Td 52.771619 Tz (second ) Tj 60.47619 0 0 60.47619 0 2875.497305 Tm 5.340945 0 Td 43.818898 Tz (designated ) Tj 2.943307 0 Td 46.161417 Tz (sequence ) Tj 2.232283 0 Td 19.291339 Tz (, ) Tj 0.446457 0 Td 39.96063 Tz (as ) Tj 0.793701 0 Td 44.783465 Tz (long ) Tj 1.388976 0 Td 38.582677 Tz (as ) Tj 0.777165 0 Td 41.338583 Tz (the ) Tj 1.058268 0 Td 46.505906 Tz (sequence ) Tj 2.513386 0 Td 38.582677 Tz (retains ) Tj 1.934646 0 Td 41.338583 Tz (the ) Tj 1.984252 0 Td 43.700787 Tz (polynucleotide ) Tj 4.067717 0 Td 46.161417 Tz (sequence ) Tj 2.596063 0 Td 35.826772 Tz (if ) Tj 0.744094 0 Td 26.181102 Tz (it ) Tj 0.694488 0 Td 39.96063 Tz (originates ) Tj 2.794488 0 Td 49.606299 Tz (from ) Tj 1.554331 0 Td 41.338583 Tz (a ) Tj 0.628346 0 Td 41.732283 Tz (foreign ) Tj 60.621118 0 0 60.621118 0 2827.956209 Tm 5.328176 0 Td 40.964822 Tz (functional ) Tj 2.787807 0 Td 38.857013 Tz (characteristics ) Tj 3.827049 0 Td 45.36373 Tz (of ) Tj 0.775307 0 Td 41.239754 Tz (the ) Tj 1.072234 0 Td 47.425717 Tz (gene ) Tj 1.451639 0 Td 41.239754 Tz (or ) Tj 0.775307 0 Td 38.883197 Tz (protein ) Tj 1.699078 0 Td 27.493169 Tz (. ) Tj 0.494877 0 Td 45.16735 Tz (Nucleic ) Tj 3.183709 0 Td 40.846995 Tz (species ) Tj 1.781557 0 Td 13.746585 Tz (, ) Tj 0.313422 0 Td 43.989071 Tz (or ) Tj 0.527869 0 Td 16.495902 Tz (, ) Tj 0.296926 0 Td 35.74112 Tz (if ) Tj 0.560861 0 Td 49.487705 Tz (from ) Tj 1.36916 0 Td 41.239754 Tz (the ) Tj 0.956762 0 Td 50.862363 Tz (same ) Tj 1.451639 0 Td 40.846995 Tz (species ) Tj 1.781557 0 Td 13.746585 Tz (, ) Tj 0.313422 0 Td 31.617145 Tz (is ) Tj 0.577357 0 Td 45.707394 Tz (modified ) Tj 2.37541 0 Td 50.862363 Tz (by ) Tj 0.791803 0 Td 56.086066 Tz (human ) Tj 64.480519 0 0 64.480519 0 2785.178129 Tm 5.009265 0 Td 38.254448 Tz (acids ) Tj 1.411279 0 Td 40.06378 Tz (or ) Tj 0.682377 0 Td 38.448305 Tz (proteins ) Tj 2.109164 0 Td 25.8476 Tz ( ) Tj 0.372205 0 Td 36.962068 Tz (consisting ) Tj 2.450352 0 Td 49.11044 Tz (of ) Tj 0.635851 0 Td 15.50856 Tz ( ) Tj 0.32568 0 Td 38.7714 Tz (a ) Tj 0.465257 0 Td 40.06378 Tz (nucleotide ) Tj 2.667472 0 Td 43.29473 Tz (sequence ) Tj 2.326284 0 Td 40.06378 Tz (or ) Tj 1.659416 0 Td 38.340606 Tz (action ) Tj 1.736959 0 Td 45.87949 Tz (from ) Tj 1.442296 0 Td 27.570773 Tz (its ) Tj 0.837462 0 Td 37.155925 Tz (original ) Tj 2.15569 0 Td 34.89426 Tz (form ) Tj 1.070091 0 Td 18.09332 Tz (. ) Tj 0.465257 0 Td 43.94092 Tz (For ) Tj 1.116616 0 Td 46.156428 Tz (example ) Tj 1.969587 0 Td 12.9238 Tz (, ) Tj 0.449748 0 Td 33.60188 Tz (a ) Tj 0.573817 0 Td 43.94092 Tz (promoter ) Tj 63.082707 0 0 63.082707 0 2743.856491 Tm 5.120262 0 Td 48.085022 Tz (amino ) Tj 1.807151 0 Td 40.291021 Tz (acid ) Tj 1.315733 0 Td 44.584327 Tz (sequence ) Tj 2.472944 0 Td 49.141836 Tz (means ) Tj 1.823004 0 Td 36.988478 Tz (that ) Tj 1.204768 0 Td 39.630513 Tz (the ) Tj 1.062098 0 Td 36.548139 Tz (entire ) Tj 1.680334 0 Td 44.584327 Tz (sequence ) Tj 2.472944 0 Td 30.383393 Tz (is ) Tj 0.887723 0 Td 26.420342 Tz (5 ) Tj 0.713349 0 Td 42.602801 Tz (operably ) Tj 2.235161 0 Td 40.95153 Tz (linked ) Tj 1.632777 0 Td 35.667461 Tz (to ) Tj 0.634088 0 Td 39.630513 Tz (a ) Tj 0.412157 0 Td 42.272547 Tz (heterologous ) Tj 3.23385 0 Td 44.033903 Tz (coding ) Tj 1.791299 0 Td 44.584327 Tz (sequence ) Tj 2.314422 0 Td 36.548139 Tz (refers ) Tj 1.505959 0 Td 35.667461 Tz (to ) Tj 57.714286 0 0 57.714286 0 2705.461859 Tm 5.561881 0 Td 46.617162 Tz (present ) Tj 1.85396 0 Td 23.10231 Tz (, ) Tj 0.571782 0 Td 51.017602 Tz (and ) Tj 1.282178 0 Td 51.980198 Tz (no ) Tj 1.039604 0 Td 41.666667 Tz (further ) Tj 2.113861 0 Td 44.366937 Tz (nucleotides ) Tj 3.326733 0 Td 44.760726 Tz (or ) Tj 0.918317 0 Td 52.557756 Tz (amino ) Tj 1.975248 0 Td 43.316832 Tz (acids ) Tj 1.715347 0 Td 42.354235 Tz (are ) Tj 60.142857 0 0 60.142857 0 2698.653997 Tm 21.548694 0 Td 41.567696 Tz (a ) Tj 0.498812 0 Td 46.186329 Tz (coding ) Tj 1.912114 0 Td 46.763658 Tz (sequence ) Tj 2.494062 0 Td 49.18844 Tz (from ) Tj 1.413302 0 Td 38.796516 Tz (a ) Tj 0.515439 0 Td 41.567696 Tz (species ) Tj 1.995249 0 Td 38.488607 Tz (different ) Tj 2.327791 0 Td 48.495645 Tz (from ) Tj 1.396675 0 Td 38.796516 Tz (that ) Tj 1.163895 0 Td 49.881235 Tz (from ) Tj 61.428571 0 0 61.428571 0 2664.898477 Tm 5.24186 0 Td 49.083862 Tz (encompassed ) Tj 3.434884 0 Td 48.837209 Tz (by ) Tj 0.813953 0 Td 40.697674 Tz (the ) Tj 0.944186 0 Td 41.472868 Tz (nucleic ) Tj 1.986047 0 Td 41.375969 Tz (acid ) Tj 1.204651 0 Td 42.054264 Tz (or ) Tj 0.7 0 Td 39.534884 Tz (protein ) Tj 1.676744 0 Td 27.131783 Tz (. ) Tj 58.571429 0 0 58.571429 0 2650.75142 Tm 22.126829 0 Td 52.357724 Tz (which ) Tj 1.912195 0 Td 42.682927 Tz (the ) Tj 1.143902 0 Td 48.729675 Tz (promoter ) Tj 2.697561 0 Td 53.116531 Tz (was ) Tj 1.365854 0 Td 44.308943 Tz (derived ) Tj 1.878049 0 Td 25.609756 Tz (, ) Tj 0.546341 0 Td 46.95122 Tz (or ) Tj 0.563415 0 Td 17.073171 Tz (, ) Tj 0.460976 0 Td 35.569106 Tz (if ) Tj 0.734146 0 Td 51.219512 Tz (from ) Tj 1.587805 0 Td 42.682927 Tz (the ) Tj 1.160976 0 Td 53.353659 Tz (same ) Tj 57.142857 0 0 57.142857 0 2622.005333 Tm 6.3 0 Td 78.75 Tz (A ) Tj 0.63 0 Td 26.25 Tz (" ) Tj 0.35 0 Td 43.333333 Tz (control ) Tj 1.9075 0 Td 26.25 Tz ( ) Tj 0.35 0 Td 46.666667 Tz (plant ) Tj 1.2425 0 Td 29.166667 Tz (, ) Tj 0.42 0 Td 42.291667 Tz (as ) Tj 0.7175 0 Td 50.3125 Tz (used ) Tj 1.4 0 Td 40.833333 Tz (in ) Tj 0.665 0 Td 43.75 Tz (the ) Tj 0.98 0 Td 45 Tz (present ) Tj 2.1 0 Td 45.046296 Tz (invention ) Tj 2.415 0 Td 26.25 Tz (, ) Tj 0.385 0 Td 40.833333 Tz (refers ) Tj 59.428571 0 0 59.428571 0 2612.5325 Tm 21.824519 0 Td 41.666667 Tz (species ) Tj 1.817308 0 Td 14.022436 Tz (, ) Tj 0.302885 0 Td 42.067308 Tz (a ) Tj 0.4375 0 Td 46.741453 Tz (coding ) Tj 1.901442 0 Td 46.97516 Tz (sequence ) Tj 2.423077 0 Td 51.041667 Tz (which ) Tj 1.716346 0 Td 32.251603 Tz (is ) Tj 0.588942 0 Td 38.951211 Tz (different ) Tj 2.288462 0 Td 49.779647 Tz (from ) Tj 1.362981 0 Td 41.132479 Tz (naturally ) Tj 60 0 0 60 0 2584.09875 Tm 5.366667 0 Td 37.5 Tz (to ) Tj 0.65 0 Td 41.666667 Tz (a ) Tj 0.416667 0 Td 41.666667 Tz (plant ) Tj 1.416667 0 Td 47.222222 Tz (used ) Tj 1.283333 0 Td 38.888889 Tz (to ) Tj 0.666667 0 Td 50.396825 Tz (compare ) Tj 2.3 0 Td 41.269841 Tz (against ) Tj 1.9 0 Td 42.222222 Tz (transgenic ) Tj 2.733333 0 Td 43.055556 Tz (or ) Tj 0.716667 0 Td 43.686869 Tz (genetically ) Tj 60.714286 0 0 60.714286 0 2566.511111 Tm 21.345882 0 Td 43.616558 Tz (occurring ) Tj 2.569412 0 Td 35.294118 Tz (allelic ) Tj 1.696471 0 Td 40.490196 Tz (variants ) Tj 1.927059 0 Td 24.705882 Tz (. ) Tj 62.857143 0 0 62.857143 0 2537.738462 Tm 5.122727 0 Td 44.081439 Tz (modified ) Tj 2.243182 0 Td 38.888889 Tz (plants ) Tj 1.575 0 Td 43.013468 Tz (according ) Tj 2.45 0 Td 37.121212 Tz (to ) Tj 0.604545 0 Td 39.772727 Tz (the ) Tj 0.859091 0 Td 41.540404 Tz (invention ) Tj 2.386364 0 Td 38.005051 Tz (for ) Tj 0.811364 0 Td 39.772727 Tz (the ) Tj 0.859091 0 Td 44.318182 Tz (purpose ) Tj 2.020455 0 Td 45.075758 Tz (of ) Tj 0.890909 0 Td 33.143939 Tz (10 ) Tj 61.428571 0 0 61.428571 0 2521.018813 Tm 21.7 0 Td 62.403101 Tz (An ) Tj 1.04186 0 Td 27.131783 Tz ( ) Tj 0.34186 0 Td 42.054264 Tz (expression ) Tj 2.816279 0 Td 38.323643 Tz (cassette ) Tj 2.018605 0 Td 21.705426 Tz ( ) Tj 0.406977 0 Td 37.984496 Tz (refers ) Tj 1.676744 0 Td 36.627907 Tz (to ) Tj 0.765116 0 Td 40.697674 Tz (a ) Tj 0.537209 0 Td 41.085271 Tz (nucleic ) Tj 2.051163 0 Td 42.054264 Tz (acid ) Tj 1.351163 0 Td 58.78553 Tz (con ) Tj 58.571429 0 0 58.571429 0 2501.6399 Tm 5.514634 0 Td 42.165558 Tz (identifying ) Tj 3.056098 0 Td 47.96748 Tz (changes ) Tj 2.304878 0 Td 39.837398 Tz (in ) Tj 0.734146 0 Td 42.682927 Tz (the ) Tj 1.02439 0 Td 43.252033 Tz (transgenic ) Tj 2.902439 0 Td 42.682927 Tz (or ) Tj 0.853659 0 Td 40.096083 Tz (genetically ) Tj 2.74878 0 Td 34.146341 Tz (- ) Tj 0.068293 0 Td 66.869919 Tz (modi ) Tj 55.714286 0 0 55.714286 0 2476 Tm 23.297436 0 Td 42.877493 Tz (struct ) Tj 1.435897 0 Td 23.931624 Tz (, ) Tj 0.484615 0 Td 54.444444 Tz (which ) Tj 1.920513 0 Td 61.324786 Tz (when ) Tj 1.776923 0 Td 47.564103 Tz (introduced ) Tj 3.158974 0 Td 41.132479 Tz (into ) Tj 1.328205 0 Td 44.871795 Tz (a ) Tj 0.574359 0 Td 46.367521 Tz (host ) Tj 1.435897 0 Td 38.141026 Tz (cell ) Tj 0.987179 0 Td 14.957265 Tz (, ) Tj 0.412821 0 Td 41.025641 Tz (results ) Tj 2.064103 0 Td 41.880342 Tz (in ) Tj 60 0 0 60 0 2457.151847 Tm 5.383333 0 Td 38.888889 Tz (fied ) Tj 1.15 0 Td 43.333333 Tz (plant ) Tj 1.2 0 Td 27.777778 Tz (. ) Tj 0.45 0 Td 52.777778 Tz (The ) Tj 1.2 0 Td 41.269841 Tz (control ) Tj 2 0 Td 41.111111 Tz (plant ) Tj 1.5 0 Td 30.555556 Tz (is ) Tj 0.65 0 Td 45.833333 Tz (of ) Tj 0.733333 0 Td 41.666667 Tz (the ) Tj 1.033333 0 Td 51.388889 Tz (same ) Tj 1.516667 0 Td 41.269841 Tz (species ) Tj 2.016667 0 Td 40.277778 Tz (as ) Tj 0.75 0 Td 41.666667 Tz (the ) Tj 60 0 0 60 0 2414.140236 Tm 5.366667 0 Td 49.074074 Tz (non ) Tj 0.983333 0 Td 27.777778 Tz (- ) Tj 0.15 0 Td 41.049383 Tz (naturally ) Tj 2.533333 0 Td 43.518519 Tz (occurring ) Tj 2.65 0 Td 42.777778 Tz (plant ) Tj 1.216667 0 Td 27.777778 Tz (. ) Tj 0.483333 0 Td 43.055556 Tz (In ) Tj 0.816667 0 Td 53.472222 Tz (some ) Tj 1.583333 0 Td 42.777778 Tz (cases ) Tj 1.333333 0 Td 13.888889 Tz (, ) Tj 0.416667 0 Td 41.666667 Tz (the ) Tj 1.05 0 Td 41.269841 Tz (control ) Tj 60 0 0 60 0 2434.23871 Tm 21.6 0 Td 40.384615 Tz (transcription ) Tj 3.433333 0 Td 50 Tz (and ) Tj 0.983333 0 Td 19.444444 Tz (/ ) Tj 0.2 0 Td 33.333333 Tz (or ) Tj 0.666667 0 Td 39.89899 Tz (translation ) Tj 2.916667 0 Td 47.222222 Tz (of ) Tj 0.8 0 Td 41.666667 Tz (a ) Tj 0.55 0 Td 72.222222 Tz (RNA ) Tj 1.55 0 Td 41.666667 Tz (or ) Tj 0.766667 0 Td 44.444444 Tz (polypeptide ) Tj 2.933333 0 Td 27.777778 Tz (, ) Tj 60.714286 0 0 60.714286 0 2375.48067 Tm 5.287059 0 Td 40.627451 Tz (plant ) Tj 1.449412 0 Td 58.562092 Tz (may ) Tj 1.268235 0 Td 48.039216 Tz (be ) Tj 0.807059 0 Td 41.176471 Tz (a ) Tj 0.477647 0 Td 44.607843 Tz (wild ) Tj 1.185882 0 Td 27.45098 Tz (- ) Tj 0.214118 0 Td 39.803922 Tz (type ) Tj 1.202353 0 Td 27.45098 Tz (\( ) Tj 0.181176 0 Td 41.633987 Tz (native ) Tj 1.515294 0 Td 27.45098 Tz (\) ) Tj 0.395294 0 Td 42.823529 Tz (plant ) Tj 1.185882 0 Td 27.45098 Tz (, ) Tj 0.444706 0 Td 44.264706 Tz (although ) Tj 2.355294 0 Td 38.736383 Tz (cultivars ) Tj 57.142857 0 0 57.142857 0 2389.768844 Tm 22.68 0 Td 42.777778 Tz (respectively ) Tj 3.0975 0 Td 29.166667 Tz (. ) Tj 0.42 0 Td 47.638889 Tz (Antisense ) Tj 2.87 0 Td 43.458333 Tz (constructs ) Tj 2.94 0 Td 43.75 Tz (or ) Tj 0.8225 0 Td 46.083333 Tz (sense ) Tj 1.68 0 Td 43.458333 Tz (constructs ) Tj 2.905 0 Td 40.833333 Tz (that ) Tj 60 0 0 60 0 2333.808989 Tm 5.383333 0 Td 49.074074 Tz (and ) Tj 1.166667 0 Td 40.909091 Tz (genetically ) Tj 3 0 Td 40.079365 Tz (altered ) Tj 1.933333 0 Td 40.740741 Tz (plants ) Tj 1.766667 0 Td 38.194444 Tz (that ) Tj 1.216667 0 Td 44.135802 Tz (otherwise ) Tj 2.666667 0 Td 48.611111 Tz (have ) Tj 1.433333 0 Td 48.611111 Tz (normal ) Tj 2.2 0 Td 33.333333 Tz (15 ) Tj 61.428571 0 0 61.428571 0 2343.977528 Tm 21.113953 0 Td 39.793282 Tz (are ) Tj 0.862791 0 Td 43.410853 Tz (not ) Tj 0.944186 0 Td 40.697674 Tz (or ) Tj 0.634884 0 Td 44.767442 Tz (cannot ) Tj 1.75814 0 Td 46.124031 Tz (be ) Tj 0.716279 0 Td 39.341085 Tz (translated ) Tj 2.523256 0 Td 39.793282 Tz (are ) Tj 0.87907 0 Td 41.903531 Tz (expressly ) Tj 2.44186 0 Td 43.410853 Tz (included ) Tj 2.213953 0 Td 50.193798 Tz (by ) Tj 0.748837 0 Td 35.949612 Tz (this ) Tj 52.857143 0 0 52.857143 0 2292 Tm 6.110811 0 Td 48.198198 Tz (disease ) Tj 2.308108 0 Td 46.351351 Tz (resistance ) Tj 3.102703 0 Td 53.603604 Tz (can ) Tj 1.267568 0 Td 44.932432 Tz (also ) Tj 1.4 0 Td 55.18018 Tz (be ) Tj 0.964865 0 Td 53.603604 Tz (used ) Tj 1.589189 0 Td 47.297297 Tz (a ) Tj 0.586486 0 Td 47.927928 Tz (references ) Tj 3.216216 0 Td 45.195195 Tz (for ) Tj 1.154054 0 Td 74.624625 Tz (com ) Tj 48.571429 0 0 48.571429 0 2307.055172 Tm 26.682353 0 Td 47.009804 Tz (definition ) Tj 2.902941 0 Td 27.45098 Tz (. ) Tj 64.285714 0 0 64.285714 0 2249.078125 Tm 5.008889 0 Td 39.62963 Tz (parison ) Tj 1.68 0 Td 25.925926 Tz (. ) Tj 0.404444 0 Td 70 Tz (A ) Tj 0.653333 0 Td 25.925926 Tz (" ) Tj 0.311111 0 Td 36.944444 Tz (wild ) Tj 1.042222 0 Td 25.925926 Tz (- ) Tj 0.186667 0 Td 40.833333 Tz (type ) Tj 1.026667 0 Td 25.925926 Tz ( ) Tj 0.42 0 Td 38.888889 Tz (plant ) Tj 1.431111 0 Td 29.814815 Tz (is ) Tj 0.653333 0 Td 38.888889 Tz (a ) Tj 0.497778 0 Td 38.37037 Tz (plant ) Tj 1.415556 0 Td 36.296296 Tz (that ) Tj 1.12 0 Td 42.345679 Tz (has ) Tj 1.042222 0 Td 40.617284 Tz (not ) Tj 0.995556 0 Td 46.018519 Tz (been ) Tj 48.571429 0 0 48.571429 0 2262 Tm 27.464706 0 Td 65.196078 Tz (The ) Tj 1.502941 0 Td 58.333333 Tz (term ) Tj 1.791176 0 Td 34.313725 Tz ( ) Tj 0.35 0 Td 47.181373 Tz (isolated ) Tj 2.367647 0 Td 34.313725 Tz ( ) Tj 0.617647 0 Td 69.485294 Tz (when ) Tj 1.976471 0 Td 59.191176 Tz (used ) Tj 1.75 0 Td 48.039216 Tz (in ) Tj 0.885294 0 Td 49.32598 Tz (relation ) Tj 2.676471 0 Td 46.323529 Tz (to ) Tj 0.926471 0 Td 51.470588 Tz (a ) Tj 0.638235 0 Td 52.45098 Tz (nucleic ) Tj 64.285714 0 0 64.285714 0 2204.035264 Tm 5.024444 0 Td 38.417508 Tz (genetically ) Tj 2.722222 0 Td 43.101852 Tz (modified ) Tj 2.271111 0 Td 38.888889 Tz (or ) Tj 0.637778 0 Td 37.777778 Tz (treated ) Tj 1.788889 0 Td 36.296296 Tz (in ) Tj 0.622222 0 Td 45.37037 Tz (an ) Tj 0.731111 0 Td 41.697531 Tz (experimental ) Tj 3.235556 0 Td 40.962963 Tz (sense ) Tj 1.275556 0 Td 10.37037 Tz (. ) Tj 0.248889 0 Td 70 Tz (A ) Tj 61.428571 0 0 61.428571 0 2215.07289 Tm 21.113953 0 Td 40.155039 Tz (acids ) Tj 1.432558 0 Td 40.697674 Tz (or ) Tj 0.667442 0 Td 40.358527 Tz (proteins ) Tj 1.986047 0 Td 13.565891 Tz (, ) Tj 0.293023 0 Td 37.984496 Tz (refers ) Tj 1.562791 0 Td 37.984496 Tz (to ) Tj 0.683721 0 Td 44.61671 Tz (sequences ) Tj 2.62093 0 Td 37.306202 Tz (that ) Tj 1.090698 0 Td 40.697674 Tz (are ) Tj 0.927907 0 Td 38.255814 Tz (identified ) Tj 2.474419 0 Td 47.932817 Tz (and ) Tj 64.642857 0 0 64.642857 0 2166.265911 Tm 4.981215 0 Td 25.782689 Tz ( ) Tj 0.293923 0 Td 37.384899 Tz (wild ) Tj 1.036464 0 Td 25.782689 Tz (- ) Tj 0.201105 0 Td 39.3186 Tz (type ) Tj 1.020994 0 Td 25.782689 Tz ( ) Tj 0.324862 0 Td 44.475138 Tz (gene ) Tj 1.222099 0 Td 28.360958 Tz (is ) Tj 0.525967 0 Td 44.689994 Tz (one ) Tj 0.943646 0 Td 36.095764 Tz (that ) Tj 1.005525 0 Td 42.111725 Tz (has ) Tj 0.912707 0 Td 38.674033 Tz (the ) Tj 0.866298 0 Td 36.267649 Tz (characteristics ) Tj 3.434254 0 Td 43.830571 Tz (of ) Tj 0.618785 0 Td 38.674033 Tz (a ) Tj 0.40221 0 Td 44.475138 Tz (gene ) Tj 2.289503 0 Td 40.106405 Tz (separated ) Tj 2.304972 0 Td 45.764273 Tz (from ) Tj 1.253039 0 Td 33.517495 Tz (at ) Tj 0.556906 0 Td 34.548803 Tz (least ) Tj 1.19116 0 Td 44.689994 Tz (one ) Tj 0.974586 0 Td 42.893019 Tz (contaminant ) Tj 2.970166 0 Td 40.220994 Tz (nucleotide ) Tj 2.567956 0 Td 39.963168 Tz (or ) Tj 0.618785 0 Td 46.40884 Tz (amino ) Tj 69.107143 0 0 69.107143 0 2120.124754 Tm 4.659432 0 Td 34.668389 Tz (isolated ) Tj 1.910078 0 Td 43.410853 Tz (from ) Tj 1.229974 0 Td 45.822567 Tz (a ) Tj 0.50646 0 Td 35.371806 Tz (naturally ) Tj 2.069251 0 Td 39.659298 Tz (occurring ) Tj 2.416537 0 Td 37.381568 Tz (source ) Tj 1.331266 0 Td 24.11714 Tz (. ) Tj 0.376227 0 Td 65.116279 Tz (A ) Tj 0.607752 0 Td 28.940568 Tz ( ) Tj 0.260465 0 Td 34.366925 Tz (wild ) Tj 0.969509 0 Td 28.940568 Tz (- ) Tj 0.231525 0 Td 34.969854 Tz (type ) Tj 0.897158 0 Td 28.940568 Tz ( ) Tj 0.52093 0 Td 32.55814 Tz (20 ) Tj 0.766925 0 Td 37.381568 Tz (acid ) Tj 1.143152 0 Td 40.39621 Tz (with ) Tj 1.229974 0 Td 44.375538 Tz (which ) Tj 1.591731 0 Td 27.734711 Tz (it ) Tj 0.564341 0 Td 27.734711 Tz (is ) Tj 0.622222 0 Td 35.211025 Tz (ordinarily ) Tj 2.402067 0 Td 36.658053 Tz (associated ) Tj 2.488889 0 Td 33.763997 Tz (in ) Tj 0.680103 0 Td 26.528854 Tz (its ) Tj 0.752455 0 Td 35.486649 Tz (natural ) Tj 60.68323 0 0 60.68323 0 2082.183741 Tm 5.322723 0 Td 47.377175 Tz (gene ) Tj 1.400716 0 Td 44.728762 Tz (product ) Tj 2.142272 0 Td 30.211532 Tz (is ) Tj 0.659161 0 Td 47.60605 Tz (one ) Tj 1.120573 0 Td 38.451041 Tz (that ) Tj 1.17001 0 Td 44.859547 Tz (has ) Tj 1.071136 0 Td 41.197544 Tz (the ) Tj 1.021699 0 Td 38.634141 Tz (characteristics ) Tj 3.773695 0 Td 46.690549 Tz (of ) Tj 0.758035 0 Td 41.197544 Tz (a ) Tj 0.527329 0 Td 47.377175 Tz (gene ) Tj 2.405937 0 Td 48.688006 Tz (environment ) Tj 3.098055 0 Td 19.22552 Tz (. ) Tj 0.362538 0 Td 46.690549 Tz (That ) Tj 1.351279 0 Td 30.211532 Tz (is ) Tj 0.411975 0 Td 13.732515 Tz (, ) Tj 0.346059 0 Td 48.063801 Tz (an ) Tj 0.790993 0 Td 39.824292 Tz (isolated ) Tj 2.109314 0 Td 41.982259 Tz (nucleic ) Tj 2.01044 0 Td 42.570795 Tz (acid ) Tj 1.235926 0 Td 42.570795 Tz (or ) Tj 0.708598 0 Td 41.589901 Tz (protein ) Tj 1.961003 0 Td 31.584783 Tz (is ) Tj 60 0 0 60 0 2040.511196 Tm 5.366667 0 Td 45.238095 Tz (product ) Tj 2.1 0 Td 39.930556 Tz (isolated ) Tj 2.1 0 Td 50 Tz (from ) Tj 1.383333 0 Td 41.666667 Tz (a ) Tj 0.433333 0 Td 41.049383 Tz (naturally ) Tj 2.416667 0 Td 43.518519 Tz (occurring ) Tj 2.566667 0 Td 42.592593 Tz (source ) Tj 1.633333 0 Td 16.666667 Tz (, ) Tj 0.3 0 Td 48.015873 Tz (whereas ) Tj 3.3 0 Td 48.148148 Tz (one ) Tj 1.05 0 Td 38.888889 Tz (that ) Tj 1.133333 0 Td 30.555556 Tz (is ) Tj 0.566667 0 Td 42.857143 Tz (present ) Tj 2 0 Td 38.888889 Tz (in ) Tj 0.65 0 Td 41.666667 Tz (a ) Tj 0.466667 0 Td 49.305556 Tz (form ) Tj 1.383333 0 Td 41.666667 Tz (or ) Tj 0.7 0 Td 38.492063 Tz (setting ) Tj 1.816667 0 Td 38.194444 Tz (that ) Tj 1.116667 0 Td 31.944444 Tz (is ) Tj 0.6 0 Td 38.580247 Tz (different ) Tj 2.266667 0 Td 50 Tz (from ) Tj 55.428571 0 0 55.428571 0 2001.31742 Tm 5.791237 0 Td 36.082474 Tz ( ) Tj 0.270619 0 Td 50.36512 Tz (modified ) Tj 2.471649 0 Td 36.082474 Tz ( ) Tj 0.523196 0 Td 49.914089 Tz (genes ) Tj 1.768041 0 Td 45.103093 Tz (or ) Tj 0.775773 0 Td 51.868557 Tz (gene ) Tj 1.479381 0 Td 48.109966 Tz (products ) Tj 2.579897 0 Td 44.100802 Tz (are ) Tj 1.028351 0 Td 46.907216 Tz (those ) Tj 1.641753 0 Td 51.116838 Tz (having ) Tj 1.966495 0 Td 56.52921 Tz (modi- ) Tj 3.085052 0 Td 42.09622 Tz (that ) Tj 1.353093 0 Td 21.04811 Tz (in ) Tj 0.649485 0 Td 54.725086 Tz (which ) Tj 1.876289 0 Td 28.565292 Tz (it ) Tj 0.595361 0 Td 34.579038 Tz (is ) Tj 0.685567 0 Td 50.515464 Tz (found ) Tj 1.822165 0 Td 39.089347 Tz (in ) Tj 0.721649 0 Td 44.601947 Tz (nature ) Tj 1.677835 0 Td 18.041237 Tz (. ) Tj 61.428571 0 0 61.428571 0 1958.006186 Tm 5.25814 0 Td 37.381568 Tz (fications ) Tj 2.44186 0 Td 39.341085 Tz (in ) Tj 0.87907 0 Td 45.445736 Tz (sequence ) Tj 2.588372 0 Td 47.028424 Tz (and ) Tj 0.960465 0 Td 18.992248 Tz (/ ) Tj 0.146512 0 Td 37.984496 Tz (or ) Tj 0.846512 0 Td 40.426357 Tz (functional ) Tj 2.832558 0 Td 40.155039 Tz (properties ) Tj 2.848837 0 Td 27.131783 Tz (\( ) Tj 0.17907 0 Td 29.166667 Tz (i.e. ) Tj 0.765116 0 Td 13.565891 Tz (, ) Tj 1.969767 0 Td 51.550388 Tz (The ) Tj 1.172093 0 Td 43.953488 Tz (terms ) Tj 1.595349 0 Td 16.27907 Tz ( ) Tj 0.146512 0 Td 48.498062 Tz (sequence ) Tj 2.588372 0 Td 37.984496 Tz (identity ) Tj 1.953488 0 Td 27.131783 Tz ( ) Tj 0.423256 0 Td 40.697674 Tz (or ) Tj 0.732558 0 Td 16.27907 Tz ( ) Tj 0.146512 0 Td 53.72093 Tz (amino ) Tj 1.888372 0 Td 41.375969 Tz (acid ) Tj 1.237209 0 Td 37.645349 Tz (identity ) Tj 1.953488 0 Td 27.131783 Tz ( ) Tj 62.857143 0 0 62.857143 0 1914.427757 Tm 5.138636 0 Td 38.257576 Tz (altered ) Tj 1.734091 0 Td 37.29798 Tz (characteristics ) Tj 3.404545 0 Td 26.515152 Tz (\) ) Tj 0.302273 0 Td 54.356061 Tz (when ) Tj 1.431818 0 Td 48.721591 Tz (compared ) Tj 2.45 0 Td 35.795455 Tz (to ) Tj 0.588636 0 Td 39.772727 Tz (the ) Tj 0.843182 0 Td 41.761364 Tz (wild ) Tj 1.113636 0 Td 26.515152 Tz (- ) Tj 0.190909 0 Td 40.435606 Tz (type ) Tj 1.113636 0 Td 45.738636 Tz (gene ) Tj 1.479545 0 Td 34.469697 Tz (25 ) Tj 0.843182 0 Td 38.888889 Tz (are ) Tj 1.081818 0 Td 45.738636 Tz (used ) Tj 1.463636 0 Td 41.098485 Tz (herein ) Tj 1.845455 0 Td 37.121212 Tz (to ) Tj 0.859091 0 Td 40.767045 Tz (describe ) Tj 2.338636 0 Td 39.772727 Tz (the ) Tj 1.129545 0 Td 44.412879 Tz (sequence ) Tj 2.513636 0 Td 38.752914 Tz (relationships ) Tj 58.63354 0 0 58.63354 0 1875.541176 Tm 5.491737 0 Td 44.058969 Tz (or ) Tj 0.801589 0 Td 49.033369 Tz (gene ) Tj 1.466737 0 Td 48.32274 Tz (product ) Tj 1.893114 0 Td 28.425141 Tz (. ) Tj 0.494597 0 Td 53.060264 Tz (The ) Tj 1.245021 0 Td 48.32274 Tz (term ) Tj 1.432627 0 Td 34.110169 Tz ( ) Tj 0.375212 0 Td 42.921963 Tz (transgenic ) Tj 2.575318 0 Td 34.110169 Tz ( ) Tj 0.528708 0 Td 32.688912 Tz (is ) Tj 0.682203 0 Td 49.033369 Tz (used ) Tj 1.449682 0 Td 44.532721 Tz (herein ) Tj 1.859004 0 Td 39.795198 Tz (to ) Tj 1.807839 0 Td 50.759181 Tz (between ) Tj 2.319492 0 Td 51.165254 Tz (two ) Tj 1.159746 0 Td 44.058969 Tz (or ) Tj 0.699258 0 Td 54.718397 Tz (more ) Tj 1.500847 0 Td 43.449859 Tz (nucleic ) Tj 2.063665 0 Td 43.34834 Tz (acid ) Tj 1.245021 0 Td 44.058969 Tz (or ) Tj 0.716314 0 Td 51.733757 Tz (amino ) Tj 1.790784 0 Td 44.058969 Tz (acid ) Tj 1.262076 0 Td 47.059401 Tz (sequences ) Tj 59.428571 0 0 59.428571 0 1833.715457 Tm 5.418269 0 Td 39.823718 Tz (refer ) Tj 1.362981 0 Td 39.262821 Tz (to ) Tj 0.689904 0 Td 42.067308 Tz (a ) Tj 0.4375 0 Td 45.432692 Tz (plant ) Tj 1.211538 0 Td 28.044872 Tz (, ) Tj 0.387019 0 Td 42.067308 Tz (a ) Tj 0.4375 0 Td 42.067308 Tz (plant ) Tj 1.480769 0 Td 39.88604 Tz (structure ) Tj 2.1875 0 Td 22.435897 Tz (, ) Tj 0.319712 0 Td 42.067308 Tz (a ) Tj 0.4375 0 Td 42.067308 Tz (plant ) Tj 1.463942 0 Td 35.757212 Tz (cell ) Tj 0.925481 0 Td 14.022436 Tz (, ) Tj 0.302885 0 Td 42.067308 Tz (a ) Tj 0.454327 0 Td 41.50641 Tz (plant ) Tj 1.430288 0 Td 39.262821 Tz (tissue ) Tj 1.463942 0 Td 14.022436 Tz (, ) Tj 1.396635 0 Td 56.790865 Tz (when ) Tj 1.53125 0 Td 43.669872 Tz (aligned ) Tj 1.985577 0 Td 41.132479 Tz (for ) Tj 0.875 0 Td 60.496795 Tz (maximum ) Tj 2.709135 0 Td 46.674679 Tz (correspondence ) Tj 4.105769 0 Td 46.274038 Tz (over ) Tj 1.262019 0 Td 42.067308 Tz (a ) Tj 0.4375 0 Td 40.820869 Tz (specified ) Tj 61.753247 0 0 61.753247 0 1791.250482 Tm 5.230494 0 Td 41.833158 Tz (or ) Tj 0.69632 0 Td 40.483701 Tz (a ) Tj 0.453417 0 Td 39.404136 Tz (plant ) Tj 1.408833 0 Td 43.857343 Tz (seed ) Tj 1.230705 0 Td 37.784788 Tz (that ) Tj 1.11735 0 Td 41.15843 Tz (contains ) Tj 2.202313 0 Td 33.736418 Tz (at ) Tj 0.615352 0 Td 36.705223 Tz (least ) Tj 1.295478 0 Td 47.680804 Tz (one ) Tj 1.052576 0 Td 43.182615 Tz (heterologous ) Tj 3.335857 0 Td 46.556257 Tz (gene ) Tj 2.364248 0 Td 46.961094 Tz (comparison ) Tj 3.011987 0 Td 53.52845 Tz (window ) Tj 1.959411 0 Td 10.795654 Tz (. ) Tj 0.307676 0 Td 51.279355 Tz (The ) Tj 1.133544 0 Td 43.452506 Tz (percentage ) Tj 2.833859 0 Td 45.881528 Tz (of ) Tj 0.680126 0 Td 35.085875 Tz ( ) Tj 0.388644 0 Td 35.760603 Tz (identity ) Tj 1.748896 0 Td 35.085875 Tz ( ) Tj 0.469611 0 Td 31.037504 Tz (is ) Tj 0.663933 0 Td 45.341746 Tz (deter ) Tj 60.654762 0 0 60.654762 0 1749.689333 Tm 5.325221 0 Td 38.469087 Tz (in ) Tj 0.61001 0 Td 48.544325 Tz (one ) Tj 1.022179 0 Td 42.590775 Tz (or ) Tj 0.626497 0 Td 52.894995 Tz (more ) Tj 1.417861 0 Td 46.712463 Tz (of ) Tj 0.642983 0 Td 30.225711 Tz (its ) Tj 0.725417 0 Td 36.270854 Tz (cells ) Tj 1.154073 0 Td 10.991168 Tz (. ) Tj 0.263788 0 Td 45.682041 Tz (Likewise ) Tj 2.242198 0 Td 24.730128 Tz (, ) Tj 0.296762 0 Td 30.225711 Tz ( ) Tj 0.379195 0 Td 38.718887 Tz (genetically ) Tj 2.654367 0 Td 27.47792 Tz (- ) Tj 0.098921 0 Td 44.651619 Tz (modified ) Tj 2.258685 0 Td 27.47792 Tz ( ) Tj 0.197841 0 Td 27.47792 Tz (, ) Tj 1.450834 0 Td 51.658489 Tz (mined ) Tj 1.731109 0 Td 50.834151 Tz (by ) Tj 0.824338 0 Td 48.239014 Tz (comparing ) Tj 2.802748 0 Td 49.460255 Tz (two ) Tj 1.121099 0 Td 43.354051 Tz (optimally ) Tj 2.555447 0 Td 43.179588 Tz (aligned ) Tj 2.02787 0 Td 45.185912 Tz (sequences ) Tj 2.670854 0 Td 45.338567 Tz (over ) Tj 62.857143 0 0 62.857143 0 1707.982955 Tm 5.138636 0 Td 15.909091 Tz ( ) Tj 0.143182 0 Td 48.721591 Tz (modified ) Tj 2.386364 0 Td 15.909091 Tz (, ) Tj 0.143182 0 Td 15.909091 Tz ( ) Tj 0.365909 0 Td 41.098485 Tz (or ) Tj 0.747727 0 Td 29.166667 Tz ( ) Tj 0.35 0 Td 41.460055 Tz (transformed ) Tj 2.784091 0 Td 23.863636 Tz (, ) Tj 0.238636 0 Td 23.863636 Tz (" ) Tj 0.413636 0 Td 35 Tz (cells ) Tj 1.113636 0 Td 13.257576 Tz (, ) Tj 0.35 0 Td 37.5 Tz (tissues ) Tj 1.622727 0 Td 13.257576 Tz (, ) Tj 0.397727 0 Td 40.833333 Tz (seeds ) Tj 1.288636 0 Td 13.257576 Tz (, ) Tj 0.365909 0 Td 39.772727 Tz (plants ) Tj 1.384091 0 Td 26.515152 Tz (, ) Tj 0.556818 0 Td 35.795455 Tz (30 ) Tj 0.827273 0 Td 39.772727 Tz (the ) Tj 0.875 0 Td 46.136364 Tz (comparison ) Tj 2.895455 0 Td 49.05303 Tz (window ) Tj 1.893182 0 Td 18.560606 Tz (. ) Tj 0.286364 0 Td 45.959596 Tz (For ) Tj 0.970455 0 Td 26.515152 Tz (" ) Tj 0.302273 0 Td 41.287879 Tz (optimal ) Tj 1.909091 0 Td 44.781145 Tz (alignment ) Tj 2.465909 0 Td 26.515152 Tz ( ) Tj 0.318182 0 Td 45.075758 Tz (of ) Tj 0.620455 0 Td 39.772727 Tz (the ) Tj 0.859091 0 Td 47.727273 Tz (two ) Tj 57.857143 0 0 57.857143 0 1668.359678 Tm 5.582716 0 Td 36.00823 Tz (etc. ) Tj 1.123457 0 Td 42.249657 Tz (are ) Tj 1.002469 0 Td 44.938272 Tz (those ) Tj 1.555556 0 Td 40.329218 Tz (that ) Tj 1.192593 0 Td 50.411523 Tz (have ) Tj 1.434568 0 Td 51.131687 Tz (been ) Tj 1.434568 0 Td 41.975309 Tz (altered ) Tj 1.953086 0 Td 40.329218 Tz (to ) Tj 0.74321 0 Td 44.444444 Tz (include ) Tj 2.108642 0 Td 43.209877 Tz (a ) Tj 0.483951 0 Td 45.770462 Tz (transgene ) Tj 3.802469 0 Td 48.010974 Tz (sequences ) Tj 2.592593 0 Td 20.164609 Tz (, ) Tj 0.483951 0 Td 28.806584 Tz (it ) Tj 0.65679 0 Td 41.049383 Tz (will ) Tj 1.330864 0 Td 48.971193 Tz (be ) Tj 0.933333 0 Td 45.043023 Tz (appreciated ) Tj 3.283951 0 Td 39.609053 Tz (that ) Tj 1.279012 0 Td 43.209877 Tz (the ) Tj 1.106173 0 Td 44.444444 Tz (portion ) Tj 2.195062 0 Td 48.971193 Tz (of ) Tj 0.82963 0 Td 44.170096 Tz (the ) Tj 62.142857 0 0 62.142857 0 1625.642132 Tm 5.197701 0 Td 42.375479 Tz (expressing ) Tj 2.848276 0 Td 46.785866 Tz (exogenous ) Tj 2.832184 0 Td 46.264368 Tz (gene ) Tj 1.383908 0 Td 42.576628 Tz (products ) Tj 2.027586 0 Td 26.819923 Tz (, ) Tj 0.482759 0 Td 38.888889 Tz (as ) Tj 0.772414 0 Td 47.509579 Tz (opposed ) Tj 2.252874 0 Td 36.206897 Tz (to ) Tj 0.756322 0 Td 47.605364 Tz (non- ) Tj 2.333333 0 Td 44.923372 Tz (sequence ) Tj 2.333333 0 Td 37.547893 Tz (in ) Tj 0.595402 0 Td 40.229885 Tz (the ) Tj 0.901149 0 Td 46.666667 Tz (comparison ) Tj 2.944828 0 Td 53.192848 Tz (window ) Tj 2.075862 0 Td 57.215837 Tz (may ) Tj 1.190805 0 Td 41.762452 Tz (include ) Tj 1.931034 0 Td 44.252874 Tz (gaps ) Tj 1.255172 0 Td 26.819923 Tz (\( ) Tj 0.193103 0 Td 33.524904 Tz (e.g. ) Tj 0.885057 0 Td 13.409962 Tz (, ) Tj 58.441558 0 0 58.441558 0 1583.553642 Tm 5.509778 0 Td 47.412037 Tz (modified ) Tj 3.114222 0 Td 27.567901 Tz (lls ) Tj 0.547556 0 Td 14.259259 Tz (, ) Tj 0.308 0 Td 39.925926 Tz (tissues ) Tj 1.745333 0 Td 14.259259 Tz (, ) Tj 0.308 0 Td 35.648148 Tz (etc. ) Tj 1.078 0 Td 54.185185 Tz (The ) Tj 1.163556 0 Td 46.2 Tz (terms ) Tj 1.608444 0 Td 41.82716 Tz (are ) Tj 0.975333 0 Td 53.044444 Tz (synonymous ) Tj 3.388 0 Td 47.768519 Tz (with ) Tj 55.396825 0 0 55.396825 0 1584.610272 Tm 23.394842 0 Td 45.12894 Tz (deletions ) Tj 2.924355 0 Td 48.137536 Tz (or ) Tj 1.823209 0 Td 42.550143 Tz (ditions ) Tj 1.732951 0 Td 27.077364 Tz (\) ) Tj 0.68596 0 Td 43.624642 Tz (as ) Tj 1.046991 0 Td 55.282951 Tz (compared ) Tj 3.140974 0 Td 40.616046 Tz (to ) Tj 1.010888 0 Td 45.12894 Tz (the ) Tj 1.317765 0 Td 46.466094 Tz (reference ) Tj 58.571429 0 0 58.571429 0 1545.816438 Tm 5.480488 0 Td 34.146341 Tz ( ) Tj 0.409756 0 Td 40.096083 Tz (genetically ) Tj 2.74878 0 Td 34.146341 Tz (- ) Tj 0.187805 0 Td 46.097561 Tz (engineered ) Tj 2.817073 0 Td 34.146341 Tz (. ) Tj 0.136585 0 Td 34.146341 Tz ( ) Tj 58.428571 0 0 58.428571 0 1542.664482 Tm 22.198044 0 Td 47.066015 Tz (sequence ) Tj 2.310513 0 Td 19.9674 Tz (, ) Tj 0.462103 0 Td 51.91524 Tz (which ) Tj 1.865526 0 Td 47.066015 Tz (does ) Tj 1.454768 0 Td 45.639772 Tz (not ) Tj 1.129584 0 Td 44.824776 Tz (contain ) Tj 2.190709 0 Td 42.470343 Tz (additions ) Tj 2.635697 0 Td 44.213529 Tz (or ) Tj 0.838631 0 Td 43.104229 Tz (deletions ) Tj 2.276284 0 Td 22.819886 Tz (. ) Tj 60 0 0 60 0 1498.027981 Tm 6.016667 0 Td 51.851852 Tz (The ) Tj 1.133333 0 Td 47.222222 Tz (term ) Tj 1.333333 0 Td 47.916667 Tz (gene ) Tj 1.366667 0 Td 33.333333 Tz (" ) Tj 0.333333 0 Td 42.222222 Tz (expression ) Tj 2.6 0 Td 33.333333 Tz ( ) Tj 0.466667 0 Td 30.555556 Tz (is ) Tj 0.566667 0 Td 47.916667 Tz (used ) Tj 1.333333 0 Td 43.518519 Tz (herein ) Tj 1.733333 0 Td 38.888889 Tz (to ) Tj 0.666667 0 Td 39.444444 Tz (refer ) Tj 1.366667 0 Td 37.5 Tz (to ) Tj 0.666667 0 Td 41.666667 Tz (the ) Tj 1.15 0 Td 36.111111 Tz (35 ) Tj 0.866667 0 Td 43.888889 Tz (After ) Tj 1.666667 0 Td 46.604938 Tz (alignment ) Tj 2.45 0 Td 27.777778 Tz (, ) Tj 0.516667 0 Td 41.666667 Tz (the ) Tj 1.083333 0 Td 53.240741 Tz (number ) Tj 2.266667 0 Td 45.833333 Tz (of ) Tj 0.833333 0 Td 50.396825 Tz (matched ) Tj 2.45 0 Td 41.049383 Tz (positions ) Tj 2.616667 0 Td 27.777778 Tz (\( ) Tj 0.183333 0 Td 29.166667 Tz (i.e. ) Tj 0.783333 0 Td 13.888889 Tz (, ) Tj 61.503759 0 0 61.503759 0 1458.011023 Tm 5.235452 0 Td 42.97066 Tz (process ) Tj 1.983619 0 Td 46.067645 Tz (of ) Tj 0.650367 0 Td 42.815811 Tz (converting ) Tj 2.73154 0 Td 41.035045 Tz (genetic ) Tj 1.902323 0 Td 43.357783 Tz (information ) Tj 3.007946 0 Td 48.00326 Tz (encoded ) Tj 2.178729 0 Td 37.93806 Tz (in ) Tj 0.601589 0 Td 40.647922 Tz (a ) Tj 0.422738 0 Td 46.74511 Tz (gene ) Tj 2.34132 0 Td 40.346826 Tz (positions ) Tj 2.325061 0 Td 49.319478 Tz (where ) Tj 1.625917 0 Td 40.647922 Tz (the ) Tj 0.894254 0 Td 37.93806 Tz (identical ) Tj 2.211247 0 Td 41.035045 Tz (nucleic ) Tj 1.902323 0 Td 41.325387 Tz (acid ) Tj 1.121883 0 Td 44.712714 Tz (base ) Tj 1.235697 0 Td 42.002852 Tz (or ) Tj 0.634108 0 Td 49.319478 Tz (amino ) Tj 1.658435 0 Td 41.325387 Tz (acid ) Tj 60 0 0 60 0 1413.861057 Tm 5.383333 0 Td 38.888889 Tz (into ) Tj 1.183333 0 Td 72.222222 Tz (RNA ) Tj 1.5 0 Td 27.777778 Tz (\( ) Tj 0.183333 0 Td 35.416667 Tz (e.g. ) Tj 0.916667 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 71.527778 Tz (mRNA ) Tj 1.766667 0 Td 25 Tz (, ) Tj 0.383333 0 Td 60.416667 Tz (rRNA ) Tj 1.5 0 Td 25 Tz (, ) Tj 0.383333 0 Td 61.111111 Tz (TRNA ) Tj 1.483333 0 Td 25 Tz (, ) Tj 0.383333 0 Td 43.055556 Tz (or ) Tj 0.75 0 Td 59.444444 Tz (snRNA ) Tj 1.85 0 Td 27.777778 Tz (\) ) Tj 0.4 0 Td 46.031746 Tz (through ) Tj 3.2 0 Td 42.460317 Tz (residue ) Tj 2.066667 0 Td 43.981481 Tz (occurs ) Tj 1.883333 0 Td 38.888889 Tz (in ) Tj 0.716667 0 Td 46.527778 Tz (both ) Tj 1.4 0 Td 46.296296 Tz (sequences ) Tj 2.5 0 Td 27.777778 Tz (\) ) Tj 0.466667 0 Td 30.555556 Tz (is ) Tj 0.666667 0 Td 46.666667 Tz (determined ) Tj 3.066667 0 Td 49.074074 Tz (and ) Tj 1.133333 0 Td 44.444444 Tz (then ) Tj 59.937888 0 0 59.937888 0 1376.224193 Tm 5.355544 0 Td 40.640361 Tz (transcription ) Tj 3.320104 0 Td 47.271157 Tz (of ) Tj 0.667358 0 Td 41.709845 Tz (the ) Tj 0.917617 0 Td 47.966321 Tz (gene ) Tj 1.351399 0 Td 27.806563 Tz (\( ) Tj 0.200207 0 Td 29.196891 Tz (i.e. ) Tj 0.767461 0 Td 13.903282 Tz (, ) Tj 0.283627 0 Td 41.709845 Tz (via ) Tj 0.917617 0 Td 41.709845 Tz (the ) Tj 0.917617 0 Td 46.962195 Tz (enzymatic ) Tj 2.719482 0 Td 42.173287 Tz (action ) Tj 1.685078 0 Td 45.880829 Tz (of ) Tj 0.667358 0 Td 48.661485 Tz (an ) Tj 1.868601 0 Td 43.696028 Tz (divided ) Tj 2.068808 0 Td 50.051813 Tz (by ) Tj 0.800829 0 Td 41.709845 Tz (the ) Tj 0.967668 0 Td 36.148532 Tz (total ) Tj 1.301347 0 Td 53.295912 Tz (number ) Tj 2.11886 0 Td 47.271157 Tz (of ) Tj 0.700725 0 Td 41.400883 Tz (positions ) Tj 2.502591 0 Td 36.148532 Tz (in ) Tj 0.63399 0 Td 41.709845 Tz (the ) Tj 0.984352 0 Td 48.105354 Tz (comparison ) Tj 59.254658 0 0 59.254658 0 1333.266084 Tm 5.451048 0 Td 73.130678 Tz (RNA ) Tj 1.501992 0 Td 47.534941 Tz (polymerase ) Tj 3.037736 0 Td 28.127184 Tz (\) ) Tj 0.050629 0 Td 28.127184 Tz (, ) Tj 0.438784 0 Td 49.691358 Tz (and ) Tj 1.147589 0 Td 38.674878 Tz (into ) Tj 1.181342 0 Td 41.387142 Tz (protein ) Tj 1.772013 0 Td 28.127184 Tz (, ) Tj 0.405031 0 Td 47.012579 Tz (through ) Tj 2.19392 0 Td 40.400864 Tz (translation ) Tj 2.902725 0 Td 47.816212 Tz (of ) Tj 1.788889 0 Td 55.785581 Tz (window ) Tj 2.042034 0 Td 11.250874 Tz (. ) Tj 0.236268 0 Td 45.003494 Tz (This ) Tj 1.248847 0 Td 38.440485 Tz (result ) Tj 1.552621 0 Td 30.939902 Tz (is ) Tj 0.523166 0 Td 45.706674 Tz (then ) Tj 1.215094 0 Td 43.597135 Tz (multiplied ) Tj 2.733962 0 Td 52.03529 Tz (by ) Tj 0.826939 0 Td 48.753785 Tz (100 ) Tj 1.012579 0 Td 37.971698 Tz (to ) Tj 0.6413 0 Td 40.940679 Tz (calculate ) Tj 2.345807 0 Td 43.128348 Tz (the ) Tj 61.428571 0 0 61.428571 0 1291.996176 Tm 5.24186 0 Td 71.899225 Tz (mRNA ) Tj 1.790698 0 Td 18.992248 Tz (. ) Tj 0.293023 0 Td 52.228682 Tz (Gene ) Tj 1.432558 0 Td 43.410853 Tz (expression ) Tj 2.767442 0 Td 46.124031 Tz (can ) Tj 0.976744 0 Td 47.48062 Tz (be ) Tj 0.732558 0 Td 41.903531 Tz (regulated ) Tj 2.425581 0 Td 35.271318 Tz (at ) Tj 0.586047 0 Td 55.620155 Tz (many ) Tj 1.530233 0 Td 39.793282 Tz (stages ) Tj 1.627907 0 Td 39.341085 Tz (in ) Tj 0.830233 0 Td 37.984496 Tz (40 ) Tj 0.862791 0 Td 43.682171 Tz (percentage ) Tj 2.913953 0 Td 46.124031 Tz (of ) Tj 0.781395 0 Td 45.445736 Tz (sequence ) Tj 2.474419 0 Td 42.054264 Tz (or ) Tj 0.765116 0 Td 49.379845 Tz (amino ) Tj 1.790698 0 Td 41.375969 Tz (acid ) Tj 1.269767 0 Td 36.28876 Tz (identity ) Tj 1.790698 0 Td 27.131783 Tz (. ) Tj 0.439535 0 Td 28.488372 Tz (It ) Tj 0.618605 0 Td 37.984496 Tz (will ) Tj 1.204651 0 Td 47.48062 Tz (be ) Tj 63.061224 0 0 63.061224 0 1250.611147 Tm 5.106149 0 Td 39.644013 Tz (the ) Tj 0.967314 0 Td 42.286947 Tz (process ) Tj 1.791909 0 Td 18.500539 Tz (. ) Tj 0.380583 0 Td 50.21575 Tz (The ) Tj 1.157605 0 Td 44.929881 Tz (term ) Tj 1.347896 0 Td 34.358145 Tz ( ) Tj 0.237864 0 Td 41.909385 Tz (overexpression ) Tj 3.615534 0 Td 34.358145 Tz ( ) Tj 0.491586 0 Td 37.001079 Tz (refers ) Tj 1.585761 0 Td 37.001079 Tz (to ) Tj 0.713592 0 Td 39.644013 Tz (the ) Tj 1.06246 0 Td 38.322546 Tz (pro- ) Tj 2.109061 0 Td 41.32588 Tz (appreciated ) Tj 2.917799 0 Td 37.001079 Tz (that ) Tj 1.110032 0 Td 39.644013 Tz (a ) Tj 0.491586 0 Td 44.269148 Tz (sequence ) Tj 2.331068 0 Td 44.929881 Tz (having ) Tj 1.839482 0 Td 39.644013 Tz (a ) Tj 0.475728 0 Td 38.133765 Tz (certain ) Tj 1.791909 0 Td 42.815534 Tz (percentage ) Tj 2.790939 0 Td 44.929881 Tz (of ) Tj 61.353383 0 0 61.353383 0 1209.641437 Tm 5.264583 0 Td 43.464052 Tz (duction ) Tj 2.021078 0 Td 46.180556 Tz (of ) Tj 0.700858 0 Td 40.747549 Tz (a ) Tj 0.472672 0 Td 46.859681 Tz (gene ) Tj 1.320221 0 Td 44.240196 Tz (product ) Tj 2.069975 0 Td 39.389297 Tz (in ) Tj 0.651961 0 Td 41.29085 Tz (transgenic ) Tj 2.705637 0 Td 39.842048 Tz (plants ) Tj 1.646201 0 Td 38.031046 Tz (that ) Tj 1.124632 0 Td 45.01634 Tz (exceeds ) Tj 3.178309 0 Td 45.50143 Tz (sequence ) Tj 2.444853 0 Td 38.370609 Tz (identity ) Tj 2.086275 0 Td 36.672794 Tz (to ) Tj 0.717157 0 Td 40.747549 Tz (a ) Tj 0.488971 0 Td 41.65305 Tz (reference ) Tj 2.526348 0 Td 45.50143 Tz (sequence ) Tj 2.444853 0 Td 44.822304 Tz (does ) Tj 1.33652 0 Td 42.558551 Tz (not ) Tj 0.99424 0 Td 54.330065 Tz (neces ) Tj 62.981366 0 0 62.981366 0 1164.433781 Tm 5.128501 0 Td 37.489042 Tz (levels ) Tj 1.619527 0 Td 44.986851 Tz (of ) Tj 0.714497 0 Td 43.134451 Tz (production ) Tj 2.826233 0 Td 38.371137 Tz (in ) Tj 0.682742 0 Td 48.074184 Tz (normal ) Tj 1.651282 0 Td 23.816568 Tz (, ) Tj 0.444576 0 Td 40.072321 Tz (control ) Tj 1.683037 0 Td 23.816568 Tz (, ) Tj 0.381065 0 Td 41.017423 Tz (or ) Tj 0.714497 0 Td 45.868946 Tz (non ) Tj 0.952663 0 Td 26.462853 Tz (- ) Tj 0.238166 0 Td 38.635766 Tz (transgenic ) Tj 3.572485 0 Td 35.283805 Tz (sarily ) Tj 1.46075 0 Td 46.309993 Tz (have ) Tj 1.286095 0 Td 37.047995 Tz (to ) Tj 0.635108 0 Td 46.309993 Tz (have ) Tj 1.301972 0 Td 39.69428 Tz (the ) Tj 0.920907 0 Td 49.61785 Tz (same ) Tj 1.365483 0 Td 34.401709 Tz (total ) Tj 1.238462 0 Td 50.279421 Tz (number ) Tj 2.000592 0 Td 43.663708 Tz (of ) Tj 0.650986 0 Td 40.656566 Tz (nucleotides ) Tj 2.889744 0 Td 41.017423 Tz (or ) Tj 59.285714 0 0 59.285714 0 1124.656619 Tm 5.431325 0 Td 42.637216 Tz (plants ) Tj 1.501205 0 Td 28.11245 Tz (. ) Tj 0.337349 0 Td 46.104418 Tz (References ) Tj 2.951807 0 Td 39.35743 Tz (to ) Tj 0.674699 0 Td 40.562249 Tz (altered ) Tj 1.872289 0 Td 30.923695 Tz ( ) Tj 0.337349 0 Td 38.888889 Tz (levels ) Tj 1.518072 0 Td 25.301205 Tz ( ) Tj 0.337349 0 Td 47.791165 Tz (of ) Tj 0.691566 0 Td 44.698795 Tz (expression ) Tj 2.850602 0 Td 38.888889 Tz (refers ) Tj 1.585542 0 Td 39.35743 Tz (to ) Tj 1.787952 0 Td 51.164659 Tz (amino ) Tj 1.872289 0 Td 41.606426 Tz (acids ) Tj 1.33253 0 Td 11.24498 Tz (. ) Tj 0.404819 0 Td 53.413655 Tz (Thus ) Tj 1.214458 0 Td 25.301205 Tz (, ) Tj 0.506024 0 Td 42.168675 Tz (a ) Tj 0.590361 0 Td 47.088353 Tz (sequence ) Tj 2.563855 0 Td 47.322624 Tz (having ) Tj 2.024096 0 Td 42.168675 Tz (a ) Tj 0.573494 0 Td 40.963855 Tz (certain ) Tj 2.024096 0 Td 39.35743 Tz (level ) Tj 1.518072 0 Td 47.791165 Tz (of ) Tj 64.285714 0 0 64.285714 0 1084.286713 Tm 5.008889 0 Td 38.888889 Tz (the ) Tj 0.84 0 Td 42 Tz (production ) Tj 2.66 0 Td 44.074074 Tz (of ) Tj 0.622222 0 Td 44.722222 Tz (gene ) Tj 1.213333 0 Td 43.333333 Tz (product ) Tj 1.882222 0 Td 25.925926 Tz (\( ) Tj 0.14 0 Td 25.925926 Tz (s ) Tj 0.186667 0 Td 25.925926 Tz (\) ) Tj 0.326667 0 Td 36.296296 Tz (in ) Tj 0.56 0 Td 43.101852 Tz (modified ) Tj 2.193333 0 Td 37.592593 Tz (plants ) Tj 1.353333 0 Td 25.925926 Tz (, ) Tj 0.342222 0 Td 43.425926 Tz (such ) Tj 1.182222 0 Td 37.592593 Tz (as ) Tj 0.824444 0 Td 35 Tz (45 ) Tj 0.855556 0 Td 33.703704 Tz ( ) Tj 0.28 0 Td 35.972222 Tz (identity ) Tj 1.742222 0 Td 33.703704 Tz ( ) Tj 0.56 0 Td 39.861111 Tz (includes ) Tj 2.271111 0 Td 42.633745 Tz (sequences ) Tj 2.644444 0 Td 35.648148 Tz (that ) Tj 1.197778 0 Td 42.777778 Tz (correspond ) Tj 2.877778 0 Td 35 Tz (to ) Tj 0.777778 0 Td 42.12963 Tz (only ) Tj 1.337778 0 Td 38.888889 Tz (a ) Tj 61.887755 0 0 61.887755 0 1043.065491 Tm 5.18681 0 Td 40.934323 Tz (transgenic ) Tj 2.6338 0 Td 39.049189 Tz (plants ) Tj 1.405771 0 Td 26.930475 Tz (, ) Tj 0.371641 0 Td 37.702666 Tz (in ) Tj 0.614015 0 Td 48.090135 Tz (amounts ) Tj 2.213685 0 Td 41.742237 Tz (or ) Tj 0.646331 0 Td 41.864648 Tz (proportions ) Tj 2.940808 0 Td 37.029404 Tz (that ) Tj 1.066447 0 Td 36.356142 Tz (differ ) Tj 1.470404 0 Td 47.801594 Tz (from ) Tj 2.391426 0 Td 41.549876 Tz (portion ) Tj 1.987469 0 Td 26.930475 Tz (\( ) Tj 0.193899 0 Td 28.276999 Tz (i.e. ) Tj 0.743281 0 Td 13.465238 Tz (, ) Tj 0.371641 0 Td 37.702666 Tz (5 ) Tj 0.290849 0 Td 10.77219 Tz (' ) Tj 0.290849 0 Td 51.167903 Tz (non ) Tj 0.937181 0 Td 24.237428 Tz (- ) Tj 0.193899 0 Td 44.884126 Tz (coding ) Tj 1.842045 0 Td 42.319318 Tz (regions ) Tj 1.728937 0 Td 26.930475 Tz (, ) Tj 0.436274 0 Td 40.395713 Tz (3 ) Tj 0.290849 0 Td 10.77219 Tz (' ) Tj 0.307007 0 Td 50.270221 Tz (non ) Tj 0.937181 0 Td 24.237428 Tz (- ) Tj 0.193899 0 Td 44.884126 Tz (coding ) Tj 1.842045 0 Td 43.858203 Tz (regions ) Tj 1.745095 0 Td 26.930475 Tz (, ) Tj 60 0 0 60 0 998.222222 Tm 5.366667 0 Td 38.888889 Tz (that ) Tj 1.166667 0 Td 45.833333 Tz (of ) Tj 0.7 0 Td 51.851852 Tz (normal ) Tj 1.75 0 Td 25 Tz (, ) Tj 0.4 0 Td 43.253968 Tz (control ) Tj 1.716667 0 Td 25 Tz (, ) Tj 0.416667 0 Td 43.055556 Tz (or ) Tj 0.716667 0 Td 47.222222 Tz (non ) Tj 1.05 0 Td 19.444444 Tz (- ) Tj 0.083333 0 Td 46.180556 Tz (modified ) Tj 2.433333 0 Td 40.740741 Tz (plants ) Tj 1.433333 0 Td 27.777778 Tz (. ) Tj 57.714286 0 0 57.714286 0 1002.793049 Tm 22.472772 0 Td 48.129813 Tz (coding ) Tj 1.957921 0 Td 44.966997 Tz (regions ) Tj 1.940594 0 Td 14.438944 Tz (, ) Tj 0.363861 0 Td 36.09736 Tz (etc. ) Tj 0.918317 0 Td 28.877888 Tz (\) ) Tj 0.433168 0 Td 49.092409 Tz (of ) Tj 0.74505 0 Td 43.316832 Tz (the ) Tj 1.00495 0 Td 44.279428 Tz (reference ) Tj 2.65099 0 Td 48.731436 Tz (sequence ) Tj 2.391089 0 Td 20.214521 Tz (. ) Tj 60.344828 0 0 60.344828 0 957.209735 Tm 5.982286 0 Td 51.555556 Tz (The ) Tj 1.309143 0 Td 46.952381 Tz (term ) Tj 1.508 0 Td 16.571429 Tz (" ) Tj 0.149143 0 Td 47.297619 Tz (operably ) Tj 2.750857 0 Td 39.126984 Tz (linked ) Tj 1.458286 0 Td 33.142857 Tz ( ) Tj 0.613143 0 Td 38.666667 Tz (refers ) Tj 1.789714 0 Td 37.285714 Tz (to ) Tj 0.828571 0 Td 42.349206 Tz (the ) Tj 1.143429 0 Td 43.006803 Tz (linkage ) Tj 2.187429 0 Td 46.952381 Tz (of ) Tj 2.369714 0 Td 55.238095 Tz (As ) Tj 0.845143 0 Td 46.952381 Tz (used ) Tj 1.276 0 Td 40.968254 Tz (herein ) Tj 1.524571 0 Td 24.857143 Tz (, ) Tj 0.314857 0 Td 41.428571 Tz (the ) Tj 0.911429 0 Td 44.650794 Tz (phrase ) Tj 1.773143 0 Td 24.857143 Tz ( ) Tj 0.314857 0 Td 43.269841 Tz (and ) Tj 0.894857 0 Td 24.857143 Tz (/ ) Tj 0.182286 0 Td 40.047619 Tz (or ) Tj 0.464 0 Td 24.857143 Tz (, ) Tj 0.232 0 Td 24.857143 Tz ( ) Tj 0.298286 0 Td 56.619048 Tz (when ) Tj 1.491429 0 Td 47.642857 Tz (used ) Tj 1.292571 0 Td 40.047619 Tz (in ) Tj 0.629714 0 Td 41.428571 Tz (a ) Tj 0.430857 0 Td 30.380952 Tz (list ) Tj 0.894857 0 Td 46.952381 Tz (of ) Tj 59.371429 0 0 59.371429 0 916.644359 Tm 5.423484 0 Td 42.909849 Tz (nucleic ) Tj 2.021174 0 Td 42.809593 Tz (acid ) Tj 1.246391 0 Td 46.162621 Tz (sequences ) Tj 2.711742 0 Td 40.704203 Tz (in ) Tj 0.690568 0 Td 47.020372 Tz (such ) Tj 1.313763 0 Td 42.107796 Tz (a ) Tj 0.437921 0 Td 52.868677 Tz (manner ) Tj 2.071704 0 Td 39.30061 Tz (that ) Tj 1.145332 0 Td 42.107796 Tz (a ) Tj 0.437921 0 Td 42.909849 Tz (nucleic ) Tj 2.021174 0 Td 43.511389 Tz (acid ) Tj 2.307507 0 Td 50.529355 Tz (two ) Tj 1.094803 0 Td 43.511389 Tz (or ) Tj 0.640038 0 Td 53.336542 Tz (more ) Tj 1.431665 0 Td 44.353545 Tz (items ) Tj 1.381136 0 Td 14.035932 Tz (, ) Tj 0.26949 0 Td 52.775104 Tz (means ) Tj 1.734841 0 Td 39.30061 Tz (that ) Tj 1.094803 0 Td 48.657898 Tz (any ) Tj 1.02743 0 Td 49.593626 Tz (one ) Tj 1.044273 0 Td 47.722169 Tz (of ) Tj 0.640038 0 Td 42.107796 Tz (the ) Tj 0.926372 0 Td 37.429152 Tz (listed ) Tj 1.482194 0 Td 44.353545 Tz (items ) Tj 1.499038 0 Td 47.722169 Tz (can ) Tj 61.428571 0 0 61.428571 0 876.224719 Tm 5.24186 0 Td 46.463178 Tz (molecule ) Tj 2.490698 0 Td 43.79845 Tz (capable ) Tj 2.1 0 Td 44.767442 Tz (of ) Tj 0.748837 0 Td 39.491817 Tz (directing ) Tj 2.376744 0 Td 40.697674 Tz (the ) Tj 0.976744 0 Td 39.654144 Tz (transcription ) Tj 3.337209 0 Td 46.124031 Tz (of ) Tj 0.748837 0 Td 40.697674 Tz (a ) Tj 0.504651 0 Td 45.03876 Tz (given ) Tj 1.725581 0 Td 36.627907 Tz (50 ) Tj 0.846512 0 Td 47.48062 Tz (be ) Tj 0.748837 0 Td 49.854651 Tz (employed ) Tj 2.539535 0 Td 48.837209 Tz (by ) Tj 0.781395 0 Td 34.819121 Tz (itself ) Tj 1.367442 0 Td 42.054264 Tz (or ) Tj 0.667442 0 Td 47.028424 Tz (any ) Tj 1.025581 0 Td 46.124031 Tz (combination ) Tj 3.206977 0 Td 44.767442 Tz (of ) Tj 0.634884 0 Td 49.741602 Tz (two ) Tj 1.090698 0 Td 42.054264 Tz (or ) Tj 0.651163 0 Td 51.550388 Tz (more ) Tj 1.416279 0 Td 46.124031 Tz (of ) Tj 59.885714 0 0 59.885714 0 834.802798 Tm 5.376908 0 Td 48.008111 Tz (gene ) Tj 1.41937 0 Td 48.240034 Tz (and ) Tj 0.968511 0 Td 19.481552 Tz (/ ) Tj 0.150286 0 Td 38.963104 Tz (or ) Tj 0.684637 0 Td 41.746183 Tz (the ) Tj 1.035305 0 Td 41.127721 Tz (synthesis ) Tj 2.504771 0 Td 47.312341 Tz (of ) Tj 0.751431 0 Td 41.746183 Tz (a ) Tj 0.500954 0 Td 42.938931 Tz (desired ) Tj 2.020515 0 Td 42.541349 Tz (protein ) Tj 2.003817 0 Td 47.660226 Tz (molecule ) Tj 2.538168 0 Td 32.005407 Tz (is ) Tj 1.686546 0 Td 41.746183 Tz (the ) Tj 1.018607 0 Td 37.107718 Tz (listed ) Tj 1.586355 0 Td 43.972646 Tz (items ) Tj 1.586355 0 Td 48.240034 Tz (can ) Tj 1.085401 0 Td 48.70388 Tz (be ) Tj 0.851622 0 Td 50.09542 Tz (employed ) Tj 2.40458 0 Td 27.830789 Tz (. ) Tj 0.450859 0 Td 48.240034 Tz (For ) Tj 1.102099 0 Td 48.902672 Tz (example ) Tj 2.070611 0 Td 27.830789 Tz (, ) Tj 0.43416 0 Td 36.180025 Tz (if ) Tj 0.617844 0 Td 41.746183 Tz (a ) Tj 0.567748 0 Td 66.793893 Tz (com ) Tj 64.214286 0 0 64.214286 0 791.924658 Tm 5.014461 0 Td 43.798665 Tz (produced ) Tj 2.133482 0 Td 25.954765 Tz (. ) Tj 0.358176 0 Td 48.448894 Tz (The ) Tj 1.043382 0 Td 44.771969 Tz (term ) Tj 1.261402 0 Td 36.985539 Tz (also ) Tj 1.074527 0 Td 36.33667 Tz (refers ) Tj 1.494994 0 Td 36.33667 Tz (to ) Tj 0.622914 0 Td 38.932147 Tz (the ) Tj 0.887653 0 Td 40.415276 Tz (linkage ) Tj 1.884316 0 Td 44.1231 Tz (of ) Tj 0.65406 0 Td 47.237671 Tz (amino ) Tj 1.619577 0 Td 40.229885 Tz (acid ) Tj 2.133482 0 Td 39.256581 Tz (position ) Tj 2.024472 0 Td 29.847979 Tz (is ) Tj 0.529477 0 Td 40.950851 Tz (described ) Tj 2.367075 0 Td 36.33667 Tz (as ) Tj 0.622914 0 Td 40.489433 Tz (containing ) Tj 2.585095 0 Td 40.229885 Tz (or ) Tj 0.622914 0 Td 42.104396 Tz (excluding ) Tj 2.429366 0 Td 46.459029 Tz (components ) Tj 60.26455 0 0 60.26455 0 749.402423 Tm 5.359701 0 Td 45.47849 Tz (sequences ) Tj 2.721335 0 Td 37.335382 Tz (in ) Tj 0.713521 0 Td 46.323529 Tz (such ) Tj 1.344074 0 Td 38.718174 Tz (a ) Tj 0.481212 0 Td 51.624232 Tz (manner ) Tj 2.107375 0 Td 41.483758 Tz (so ) Tj 0.730114 0 Td 38.718174 Tz (that ) Tj 1.178139 0 Td 38.718174 Tz (a ) Tj 0.481212 0 Td 41.483758 Tz (functional ) Tj 2.721335 0 Td 42.273924 Tz (protein ) Tj 1.99122 0 Td 31.804214 Tz (is ) Tj 1.675944 0 Td 74.670764 Tz (A ) Tj 0.481212 0 Td 13.827919 Tz (, ) Tj 0.365057 0 Td 60.842845 Tz (B ) Tj 0.414838 0 Td 13.827919 Tz (, ) Tj 0.365057 0 Td 47.936787 Tz (and ) Tj 0.94583 0 Td 19.359087 Tz (/ ) Tj 0.149342 0 Td 40.100966 Tz (or ) Tj 0.713521 0 Td 63.608428 Tz (C ) Tj 0.431431 0 Td 13.827919 Tz (, ) Tj 0.33187 0 Td 42.405619 Tz (the ) Tj 0.99561 0 Td 46.512092 Tz (composition ) Tj 3.302107 0 Td 47.014925 Tz (can ) Tj 1.078578 0 Td 43.064091 Tz (contain ) Tj 2.041001 0 Td 42.86655 Tz (or ) Tj 0.746708 0 Td 45.039508 Tz (exclude ) Tj 2.090781 0 Td 74.670764 Tz (A ) Tj 58.571429 0 0 58.571429 0 716 Tm 5.497561 0 Td 49.796748 Tz (produced ) Tj 57.142857 0 0 57.142857 0 709 Tm 22.6975 0 Td 47.25 Tz (alone ) Tj 1.3825 0 Td 26.25 Tz (; ) Tj 0.42 0 Td 64.166667 Tz (B ) Tj 0.6475 0 Td 46.666667 Tz (alone ) Tj 1.4525 0 Td 14.583333 Tz (; ) Tj 0.3675 0 Td 67.083333 Tz (C ) Tj 0.6475 0 Td 46.083333 Tz (alone ) Tj 1.4525 0 Td 14.583333 Tz (; ) Tj 0.2975 0 Td 78.75 Tz (A ) Tj 0.665 0 Td 51.527778 Tz (and ) Tj 1.155 0 Td 64.166667 Tz (B ) Tj 0.6475 0 Td 40.833333 Tz (in ) Tj 0.7175 0 Td 47.992424 Tz (combination ) Tj 3.255 0 Td 26.25 Tz (; ) Tj 0.35 0 Td 78.75 Tz (A ) Tj 0.665 0 Td 51.527778 Tz (and ) Tj 1.155 0 Td 67.083333 Tz (C ) Tj 54.285714 0 0 54.285714 0 668 Tm 6.65 0 Td 57.309942 Tz (The ) Tj 1.307895 0 Td 52.960526 Tz (term ) Tj 1.547368 0 Td 21.491228 Tz ( ) Tj 0.368421 0 Td 45.540936 Tz (vector ) Tj 1.786842 0 Td 24.561404 Tz ( ) Tj 0.423684 0 Td 42.982456 Tz (refers ) Tj 1.842105 0 Td 41.447368 Tz (to ) Tj 0.792105 0 Td 46.491228 Tz (nucleic ) Tj 2.265789 0 Td 47.587719 Tz (acid ) Tj 1.4 0 Td 51.169591 Tz (molecules ) Tj 3.057895 0 Td 42.982456 Tz (that ) Tj 1.473684 0 Td 39.912281 Tz (55 ) Tj 0.976316 0 Td 42.982456 Tz (in ) Tj 0.736842 0 Td 50.518341 Tz (combination ) Tj 3.407895 0 Td 27.631579 Tz (; ) Tj 0.442105 0 Td 67.54386 Tz (B ) Tj 0.663158 0 Td 54.239766 Tz (and ) Tj 1.197368 0 Td 70.614035 Tz (C ) Tj 0.663158 0 Td 42.982456 Tz (in ) Tj 0.736842 0 Td 51.076555 Tz (combination ) Tj 3.426316 0 Td 27.631579 Tz (; ) Tj 0.423684 0 Td 46.052632 Tz (or ) Tj 0.718421 0 Td 82.894737 Tz (A ) Tj 0.534211 0 Td 15.350877 Tz (, ) Tj 0.35 0 Td 67.54386 Tz (B ) Tj 0.478947 0 Td 15.350877 Tz (, ) Tj 0.368421 0 Td 54.239766 Tz (and ) Tj 1.197368 0 Td 70.614035 Tz (C ) Tj 0.663158 0 Td 42.982456 Tz (in ) Tj 58.214286 0 0 58.214286 0 625.880446 Tm 5.531288 0 Td 41.155419 Tz (transfer ) Tj 2.147239 0 Td 76.346285 Tz (DNA ) Tj 1.528834 0 Td 51.124744 Tz (segment ) Tj 2.198773 0 Td 28.629857 Tz (\( ) Tj 0.206135 0 Td 28.629857 Tz (s ) Tj 0.188957 0 Td 28.629857 Tz (\) ) Tj 0.377914 0 Td 51.533742 Tz (from ) Tj 1.408589 0 Td 50.579414 Tz (one ) Tj 1.099387 0 Td 36.503067 Tz (cell ) Tj 1.065031 0 Td 40.0818 Tz (to ) Tj 0.687117 0 Td 45.398773 Tz (another ) Tj 1.906748 0 Td 20.0409 Tz (. ) Tj 0.292025 0 Td 54.396728 Tz (The ) Tj 1.15092 0 Td 48.670757 Tz (term ) Tj 2.47362 0 Td 48.410485 Tz (combination ) Tj 3.246626 0 Td 11.451943 Tz (. ) Tj 61.904762 0 0 61.904762 0 583.575502 Tm 5.217692 0 Td 41.057692 Tz (includes ) Tj 2.196923 0 Td 45.769231 Tz (recombinant ) Tj 3.230769 0 Td 71.794872 Tz (DNA ) Tj 1.453846 0 Td 45.17094 Tz (molecules ) Tj 2.665385 0 Td 42.269231 Tz (containing ) Tj 2.746154 0 Td 40.384615 Tz (a ) Tj 0.468462 0 Td 41.538462 Tz (desired ) Tj 3.57 0 Td 51.153846 Tz (The ) Tj 1.227692 0 Td 41.153846 Tz (present ) Tj 2.051538 0 Td 40.629371 Tz (description ) Tj 2.972308 0 Td 39.038462 Tz (also ) Tj 1.26 0 Td 42.403846 Tz (uses ) Tj 1.324615 0 Td 44.57265 Tz (numerical ) Tj 2.713846 0 Td 43.076923 Tz (ranges ) Tj 1.873846 0 Td 36.346154 Tz (to ) Tj 61.428571 0 0 61.428571 0 543.675229 Tm 5.25814 0 Td 45.219638 Tz (coding ) Tj 1.872093 0 Td 45.106589 Tz (sequence ) Tj 2.27907 0 Td 27.131783 Tz (\( ) Tj 0.195349 0 Td 27.131783 Tz (s ) Tj 0.17907 0 Td 27.131783 Tz (\) ) Tj 0.406977 0 Td 47.932817 Tz (and ) Tj 1.074419 0 Td 41.684285 Tz (appropriate ) Tj 2.962791 0 Td 41.085271 Tz (nucleic ) Tj 1.969767 0 Td 42.054264 Tz (acid ) Tj 1.237209 0 Td 44.61671 Tz (sequences ) Tj 3.662791 0 Td 41.715116 Tz (quantify ) Tj 2.165116 0 Td 39.147287 Tz (certain ) Tj 1.790698 0 Td 44.224806 Tz (parameters ) Tj 2.816279 0 Td 38.323643 Tz (relating ) Tj 2.002326 0 Td 36.627907 Tz (to ) Tj 0.618605 0 Td 41.860465 Tz (various ) Tj 1.953488 0 Td 49.083862 Tz (embodiments ) Tj 58.198758 0 0 58.198758 0 504.781726 Tm 5.567129 0 Td 28.637496 Tz (\( ) Tj 0.20619 0 Td 35.796869 Tz (e.g. ) Tj 0.945037 0 Td 14.318748 Tz (, ) Tj 0.34365 0 Td 48.365548 Tz (promoters ) Tj 2.628922 0 Td 28.637496 Tz (\) ) Tj 0.429562 0 Td 46.138187 Tz (necessary ) Tj 2.7492 0 Td 41.047077 Tz (for ) Tj 0.96222 0 Td 42.956243 Tz (the ) Tj 1.048132 0 Td 45.533618 Tz (expression ) Tj 2.972572 0 Td 48.683742 Tz (of ) Tj 0.75603 0 Td 42.956243 Tz (the ) Tj 1.048132 0 Td 45.819993 Tz (oper- ) Tj 2.628922 0 Td 48.683742 Tz (of ) Tj 0.6873 0 Td 42.956243 Tz (the ) Tj 0.979402 0 Td 43.592632 Tz (invention ) Tj 2.422732 0 Td 20.046247 Tz (. ) Tj 0.34365 0 Td 30.06937 Tz (It ) Tj 0.584205 0 Td 46.774576 Tz (should ) Tj 1.85571 0 Td 48.683742 Tz (be ) Tj 0.773212 0 Td 47.824618 Tz (understood ) Tj 3.02412 0 Td 40.092494 Tz (that ) Tj 1.151227 0 Td 57.990928 Tz (when ) Tj 1.58079 0 Td 56.320408 Tz (numeri ) Tj 62.857143 0 0 62.857143 0 461.030246 Tm 5.138636 0 Td 41.761364 Tz (ably ) Tj 1.161364 0 Td 41.098485 Tz (linked ) Tj 1.638636 0 Td 44.191919 Tz (coding ) Tj 1.765909 0 Td 44.744318 Tz (sequence ) Tj 2.306818 0 Td 38.44697 Tz (in ) Tj 0.604545 0 Td 39.772727 Tz (a ) Tj 0.381818 0 Td 38.181818 Tz (particular ) Tj 2.434091 0 Td 41.098485 Tz (host ) Tj 1.145455 0 Td 40.435606 Tz (organism ) Tj 2.131818 0 Td 26.515152 Tz (. ) Tj 0.35 0 Td 29.166667 Tz (It ) Tj 0.747727 0 Td 34.469697 Tz (60 ) Tj 0.827273 0 Td 36.237374 Tz (cal ) Tj 0.859091 0 Td 42.424242 Tz (ranges ) Tj 1.75 0 Td 38.888889 Tz (are ) Tj 0.906818 0 Td 43.418561 Tz (provided ) Tj 2.1 0 Td 26.515152 Tz (, ) Tj 0.381818 0 Td 44.412879 Tz (such ) Tj 1.240909 0 Td 42.424242 Tz (ranges ) Tj 1.75 0 Td 38.888889 Tz (are ) Tj 0.890909 0 Td 37.121212 Tz (to ) Tj 0.652273 0 Td 46.401515 Tz (be ) Tj 0.763636 0 Td 42.718855 Tz (construed ) Tj 2.497727 0 Td 38.44697 Tz (as ) Tj 60.37594 0 0 60.37594 0 419.301344 Tm 5.366376 0 Td 30.365297 Tz (is ) Tj 0.695641 0 Td 46.928186 Tz (used ) Tj 1.457534 0 Td 43.431576 Tz (interchangeably ) Tj 4.2401 0 Td 43.247544 Tz (herein ) Tj 1.888169 0 Td 44.167704 Tz (with ) Tj 1.391283 0 Td 42.327383 Tz (the ) Tj 1.060025 0 Td 46.928186 Tz (term ) Tj 1.457534 0 Td 33.125778 Tz (" ) Tj 0.298132 0 Td 45.350768 Tz (plasmid ) Tj 1.954421 0 Td 33.125778 Tz (. ) Tj 1.639726 0 Td 44.474425 Tz (providing ) Tj 2.550685 0 Td 33.520133 Tz (literal ) Tj 1.590037 0 Td 43.378995 Tz (support ) Tj 1.970984 0 Td 39.566902 Tz (for ) Tj 0.844707 0 Td 45.271897 Tz (claim ) Tj 1.507223 0 Td 39.3996 Tz (limitations ) Tj 2.74944 0 Td 38.646741 Tz (that ) Tj 1.076588 0 Td 44.857825 Tz (only ) Tj 1.209091 0 Td 38.186661 Tz (recite ) Tj 57.142857 0 0 57.142857 0 376.623926 Tm 5.635 0 Td 52.864583 Tz (Examples ) Tj 2.94 0 Td 49.583333 Tz (of ) Tj 0.9275 0 Td 41.5625 Tz (suitable ) Tj 2.38 0 Td 44.166667 Tz (vectors ) Tj 2.275 0 Td 41.805556 Tz (for ) Tj 1.1025 0 Td 50.3125 Tz (used ) Tj 1.575 0 Td 42.291667 Tz (in ) Tj 0.8575 0 Td 43.75 Tz (the ) Tj 1.19 0 Td 45.37037 Tz (invention ) Tj 3.7975 0 Td 43.75 Tz (the ) Tj 0.98 0 Td 49.583333 Tz (lower ) Tj 1.6275 0 Td 47.25 Tz (value ) Tj 1.5925 0 Td 49.583333 Tz (of ) Tj 0.7 0 Td 43.75 Tz (the ) Tj 0.945 0 Td 48.416667 Tz (range ) Tj 1.645 0 Td 40.833333 Tz (as ) Tj 0.6825 0 Td 45.9375 Tz (well ) Tj 1.295 0 Td 42.291667 Tz (as ) Tj 0.7175 0 Td 47.833333 Tz (claim ) Tj 1.61 0 Td 41.628788 Tz (limitations ) Tj 2.94 0 Td 40.833333 Tz (that ) Tj 63.544974 0 0 63.544974 0 335.724609 Tm 5.098751 0 Td 40.466278 Tz (include ) Tj 1.856953 0 Td 55.516236 Tz (PACH20 ) Tj 2.077269 0 Td 26.228143 Tz (, ) Tj 0.314738 0 Td 47.210658 Tz (pJL ) Tj 0.944213 0 Td 47.210658 Tz (10P5 ) Tj 1.133056 0 Td 23.605329 Tz (, ) Tj 0.314738 0 Td 54.204829 Tz (pGmubi ) Tj 1.904163 0 Td 26.228143 Tz (, ) Tj 0.299001 0 Td 57.701915 Tz (PACH17 ) Tj 2.140216 0 Td 15.736886 Tz (, ) Tj 0.25179 0 Td 45.462115 Tz (and ) Tj 1.007161 0 Td 38.467943 Tz (the ) Tj 0.849792 0 Td 34.75229 Tz (like ) Tj 0.881266 0 Td 18.3597 Tz (. ) Tj 1.337635 0 Td 42.620733 Tz (only ) Tj 1.290425 0 Td 35.845129 Tz (recite ) Tj 1.557952 0 Td 39.342215 Tz (the ) Tj 0.975687 0 Td 45.112406 Tz (upper ) Tj 1.605162 0 Td 41.965029 Tz (value ) Tj 1.542215 0 Td 44.587843 Tz (of ) Tj 0.723897 0 Td 39.342215 Tz (the ) Tj 0.975687 0 Td 43.538718 Tz (range ) Tj 1.306162 0 Td 18.3597 Tz (. ) Tj 0.424896 0 Td 44.587843 Tz (For ) Tj 1.070108 0 Td 46.83597 Tz (example ) Tj 1.935637 0 Td 26.228143 Tz (, ) Tj 0.472107 0 Td 39.342215 Tz (a ) Tj 58.831169 0 0 58.831169 0 293.951321 Tm 6.136203 0 Td 52.882021 Tz (The ) Tj 1.325828 0 Td 48.868653 Tz (term ) Tj 1.529801 0 Td 31.16262 Tz ( ) Tj 0.339956 0 Td 40.605838 Tz (transform ) Tj 2.447682 0 Td 31.16262 Tz ( ) Tj 0.645916 0 Td 31.16262 Tz (is ) Tj 0.764901 0 Td 48.868653 Tz (used ) Tj 1.529801 0 Td 44.383125 Tz (herein ) Tj 1.954746 0 Td 39.661516 Tz (to ) Tj 0.866887 0 Td 40.228109 Tz (refer ) Tj 1.563797 0 Td 38.245033 Tz (to ) Tj 0.866887 0 Td 42.494481 Tz (the ) Tj 2.073731 0 Td 43.753577 Tz (disclosed ) Tj 2.498675 0 Td 46.586542 Tz (numerical ) Tj 2.685651 0 Td 46.460633 Tz (range ) Tj 1.580795 0 Td 46.743929 Tz (of ) Tj 0.662914 0 Td 46.460633 Tz (about ) Tj 1.61479 0 Td 46.743929 Tz (10 ) Tj 0.713907 0 Td 39.661516 Tz (to ) Tj 0.662914 0 Td 46.460633 Tz (about ) Tj 1.61479 0 Td 48.160412 Tz (100 ) Tj 1.019868 0 Td 45.327447 Tz (provides ) Tj 60 0 0 60 0 250.77533 Tm 5.383333 0 Td 42.12963 Tz (introduction ) Tj 3.2 0 Td 47.222222 Tz (of ) Tj 0.683333 0 Td 42.460317 Tz (foreign ) Tj 1.95 0 Td 74.074074 Tz (DNA ) Tj 1.483333 0 Td 38.194444 Tz (into ) Tj 1.116667 0 Td 36.666667 Tz (cells ) Tj 1.183333 0 Td 11.111111 Tz (. ) Tj 0.266667 0 Td 45.833333 Tz (Transformation ) Tj 4 0 Td 59.259259 Tz (may ) Tj 1.483333 0 Td 34.722222 Tz (65 ) Tj 0.866667 0 Td 33.730159 Tz (literal ) Tj 1.683333 0 Td 43.650794 Tz (support ) Tj 2.083333 0 Td 39.814815 Tz (for ) Tj 0.95 0 Td 41.666667 Tz (a ) Tj 0.5 0 Td 45.555556 Tz (claim ) Tj 1.583333 0 Td 39.583333 Tz (reciting ) Tj 2.133333 0 Td 25 Tz (" ) Tj 0.433333 0 Td 37.698413 Tz (greater ) Tj 1.783333 0 Td 45.138889 Tz (than ) Tj 1.316667 0 Td 45.555556 Tz (about ) Tj 1.65 0 Td 44.444444 Tz (10 ) Tj 0.683333 0 Td 25 Tz (" ) Tj 61.868132 0 0 61.868132 0 211.704908 Tm 5.204618 0 Td 47.14328 Tz (be ) Tj 0.743517 0 Td 46.020821 Tz (accomplished ) Tj 3.45897 0 Td 48.490231 Tz (by ) Tj 0.75968 0 Td 40.408526 Tz (a ) Tj 0.404085 0 Td 40.023683 Tz (variety ) Tj 1.858792 0 Td 44.449378 Tz (of ) Tj 0.630373 0 Td 50.645352 Tz (means ) Tj 1.697158 0 Td 54.955595 Tz (known ) Tj 1.794139 0 Td 36.367673 Tz (to ) Tj 0.630373 0 Td 40.408526 Tz (the ) Tj 0.905151 0 Td 34.122755 Tz (art ) Tj 0.775844 0 Td 48.490231 Tz (and ) Tj 2.101243 0 Td 26.939017 Tz (\( ) Tj 0.242451 0 Td 41.755477 Tz (with ) Tj 1.147602 0 Td 47.14328 Tz (no ) Tj 0.743517 0 Td 46.33511 Tz (upper ) Tj 1.519361 0 Td 47.592264 Tz (bounds ) Tj 1.761812 0 Td 26.939017 Tz (\) ) Tj 0.339432 0 Td 47.592264 Tz (and ) Tj 1.018295 0 Td 40.408526 Tz (a ) Tj 0.404085 0 Td 44.179988 Tz (claim ) Tj 1.47087 0 Td 38.388099 Tz (reciting ) Tj 2.004263 0 Td 24.245115 Tz ( ) Tj 0.290941 0 Td 35.020722 Tz (less ) Tj 1.018295 0 Td 43.775903 Tz (than ) Tj 1.196092 0 Td 44.179988 Tz (about ) Tj 48.571429 0 0 48.571429 0 174 Tm 6.65 0 Td 54.520697 Tz (described ) Tj 3.191176 0 Td 50.326797 Tz (herein ) Tj 1.914706 0 Td 24.019608 Tz (. ) Tj 55.873016 0 0 55.873016 0 167.435696 Tm 23.267045 0 Td 46.732955 Tz (100 ) Tj 1.055966 0 Td 26.846591 Tz ( ) Tj 0.429545 0 Td 29.829545 Tz (\( ) Tj 0.214773 0 Td 48.473011 Tz (with ) Tj 1.396023 0 Td 52.201705 Tz (no ) Tj 0.894886 0 Td 50.710227 Tz (lower ) Tj 1.73608 0 Td 54.6875 Tz (bounds ) Tj 2.040341 0 Td 29.829545 Tz (\) ) Tj 0.107386 0 Td 29.829545 Tz (. ) Tj ET Q endstream endobj 179 0 obj << /Length 1 >> stream q endstream endobj 180 0 obj << /Length 63523 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 60.47619 0 0 60.47619 0 3027.186747 Tm 17.659843 0 Td 85.433071 Tz (US ) Tj 1.455118 0 Td 59.527559 Tz (11,072,799 ) Tj 3.902362 0 Td 74.409449 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.563889 0 Td 61.574074 Tz (11 ) Tj 55.714286 0 0 55.714286 0 2968 Tm 30.907692 0 Td 65.811966 Tz (12 ) Tj 62.773109 0 0 62.773109 0 2914.163399 Tm 5.75087 0 Td 37.170906 Tz (In ) Tj 0.764659 0 Td 40.120978 Tz (preferred ) Tj 2.517001 0 Td 48.273904 Tz (embodiments ) Tj 3.504685 0 Td 47.791165 Tz (of ) Tj 0.82838 0 Td 38.940949 Tz (the ) Tj 1.051406 0 Td 38.940949 Tz (invention ) Tj 2.182463 0 Td 23.895582 Tz (, ) Tj 0.493842 0 Td 45.1361 Tz (an ) Tj 0.923963 0 Td 54.428826 Tz (FHB1 ) Tj 2.612584 0 Td 42.746542 Tz (percentage ) Tj 2.740027 0 Td 43.808568 Tz (of ) Tj 0.653146 0 Td 44.472334 Tz (sequence ) Tj 2.293976 0 Td 37.502789 Tz (identity ) Tj 1.959438 0 Td 44.605087 Tz (determined ) Tj 2.803748 0 Td 49.118697 Tz (by ) Tj 0.764659 0 Td 40.963855 Tz (scoring ) Tj 1.911647 0 Td 49.782463 Tz (iden ) Tj 58.901099 0 0 58.901099 0 2872.961957 Tm 5.449813 0 Td 42.848259 Tz (protein ) Tj 2.071269 0 Td 45.273632 Tz (has ) Tj 1.1375 0 Td 28.29602 Tz ( ) Tj 0.339552 0 Td 58.006841 Tz (FHB1 ) Tj 1.833582 0 Td 37.845927 Tz (activity ) Tj 1.85056 0 Td 33.955224 Tz (, ) Tj 0.135821 0 Td 33.955224 Tz ( ) Tj 0.526306 0 Td 49.989635 Tz (and ) Tj 1.188433 0 Td 49.518035 Tz (an ) Tj 0.882836 0 Td 16.977612 Tz ( ) Tj 0.152799 0 Td 55.177239 Tz (Fhbl ) Tj 1.680784 0 Td 43.252488 Tz (nucleic ) Tj 2.139179 0 Td 41.029229 Tz (acid ) Tj 1.06959 0 Td 33.955224 Tz ( ) Tj 1.527985 0 Td 36.218905 Tz (tical ) Tj 1.324254 0 Td 51.498756 Tz (amino ) Tj 1.782649 0 Td 42.44403 Tz (acids ) Tj 1.511007 0 Td 41.029229 Tz (as ) Tj 0.78097 0 Td 28.29602 Tz (1 ) Tj 0.475373 0 Td 49.989635 Tz (and ) Tj 1.103545 0 Td 49.989635 Tz (any ) Tj 1.1375 0 Td 40.793429 Tz (substitution ) Tj 3.157836 0 Td 39.614428 Tz (as ) Tj 0.730037 0 Td 41.029229 Tz (zero ) Tj 1.06959 0 Td 19.807214 Tz (, ) Tj 0.458396 0 Td 49.518035 Tz (regard ) Tj 58.628571 0 0 58.628571 0 2830.508783 Tm 5.509259 0 Td 47.920728 Tz (encodes ) Tj 2.217349 0 Td 42.641326 Tz (a ) Tj 0.426413 0 Td 43.047433 Tz (protein ) Tj 1.961501 0 Td 48.326836 Tz (having ) Tj 1.927388 0 Td 28.42755 Tz ( ) Tj 0.272904 0 Td 61.119233 Tz (FHB1 ) Tj 1.756823 0 Td 38.377193 Tz (activity ) Tj 1.876218 0 Td 34.11306 Tz (. ) Tj 0.136452 0 Td 34.11306 Tz ( ) Tj 0.426413 0 Td 53.064761 Tz (The ) Tj 1.125731 0 Td 49.037524 Tz (term ) Tj 1.347466 0 Td 31.270305 Tz ( ) Tj 0.341131 0 Td 59.697856 Tz (FHB1 ) Tj 2.797271 0 Td 38.377193 Tz (less ) Tj 1.091618 0 Td 48.326836 Tz (of ) Tj 0.648148 0 Td 42.641326 Tz (the ) Tj 0.955166 0 Td 40.082846 Tz (similarity ) Tj 2.575536 0 Td 46.905458 Tz (of ) Tj 0.648148 0 Td 51.453866 Tz (mismatched ) Tj 3.240741 0 Td 51.169591 Tz (amino ) Tj 1.72271 0 Td 42.641326 Tz (acids ) Tj 1.347466 0 Td 11.37102 Tz (. ) Tj 0.255848 0 Td 44.062703 Tz (In ) Tj 0.682261 0 Td 42.641326 Tz (a ) Tj 0.3923 0 Td 41.423002 Tz (typical ) Tj 65.779221 0 0 65.779221 0 2788.82529 Tm 4.910365 0 Td 33.571899 Tz (activity ) Tj 1.778677 0 Td 25.337282 Tz ( ) Tj 0.304047 0 Td 35.049907 Tz (refers ) Tj 1.429023 0 Td 34.205331 Tz (to ) Tj 0.562488 0 Td 38.850499 Tz (the ) Tj 0.851333 0 Td 56.586596 Tz (FHB ) Tj 1.170582 0 Td 17.736097 Tz (- ) Tj 0.167226 0 Td 36.232313 Tz (resistance ) Tj 2.325962 0 Td 37.031412 Tz (functionality ) Tj 3.025271 0 Td 42.439947 Tz (provided ) Tj 3.192498 0 Td 42.439947 Tz (sequence ) Tj 2.189141 0 Td 43.073379 Tz (alignment ) Tj 2.234748 0 Td 30.404738 Tz (, ) Tj 0.31925 0 Td 31.671603 Tz (e.g. ) Tj 0.83613 0 Td 12.668641 Tz (, ) Tj 0.243238 0 Td 38.005923 Tz (a ) Tj 0.380059 0 Td 59.28924 Tz (BLAST ) Tj 1.915499 0 Td 43.354905 Tz (alignment ) Tj 2.219546 0 Td 25.337282 Tz (, ) Tj 0.31925 0 Td 38.005923 Tz (the ) Tj 0.83613 0 Td 25.337282 Tz ( ) Tj 0.31925 0 Td 37.689207 Tz (absolute ) Tj 67.142857 0 0 67.142857 0 2747.149904 Tm 4.795745 0 Td 45.921986 Tz (by ) Tj 0.670213 0 Td 37.234043 Tz (the ) Tj 0.804255 0 Td 53.368794 Tz (FHB1 ) Tj 1.459574 0 Td 37.943262 Tz (protein ) Tj 1.697872 0 Td 41.78487 Tz (having ) Tj 1.623404 0 Td 37.234043 Tz (the ) Tj 0.804255 0 Td 45.177305 Tz (amino ) Tj 1.504255 0 Td 38.475177 Tz (acid ) Tj 1.057447 0 Td 41.888298 Tz (sequence ) Tj 2.144681 0 Td 42.198582 Tz (of ) Tj 0.595745 0 Td 55.437352 Tz (SEQ ) Tj 1.474468 0 Td 27.304965 Tz (5 ) Tj 0.670213 0 Td 39.007092 Tz (percent ) Tj 1.891489 0 Td 37.234043 Tz (identity ) Tj 1.831915 0 Td 14.893617 Tz ( ) Tj 0.357447 0 Td 40.957447 Tz (of ) Tj 0.685106 0 Td 44.680851 Tz (two ) Tj 1.102128 0 Td 40.819543 Tz (sequences ) Tj 2.47234 0 Td 28.546099 Tz (is ) Tj 0.595745 0 Td 39.716312 Tz (presented ) Tj 2.382979 0 Td 35.992908 Tz (as ) Tj 0.7 0 Td 37.234043 Tz (a ) Tj 0.53617 0 Td 47.990544 Tz (per ) Tj 61.020408 0 0 61.020408 0 2705.315016 Tm 5.293311 0 Td 51.895206 Tz (ID ) Tj 0.819398 0 Td 72.380156 Tz (NO ) Tj 0.934114 0 Td 10.925307 Tz (: ) Tj 0.131104 0 Td 40.9699 Tz (3 ) Tj 0.327759 0 Td 13.656633 Tz (, ) Tj 0.327759 0 Td 43.701226 Tz (and ) Tj 0.983278 0 Td 19.119287 Tz (/ ) Tj 0.147492 0 Td 35.507246 Tz (or ) Tj 0.606355 0 Td 40.9699 Tz (the ) Tj 0.950502 0 Td 61.910071 Tz (FHB ) Tj 1.245485 0 Td 19.119287 Tz (- ) Tj 0.147492 0 Td 39.877369 Tz (resistance ) Tj 2.605686 0 Td 39.709287 Tz (functionality ) Tj 3.29398 0 Td 45.749721 Tz (provided ) Tj 3.441472 0 Td 44.091416 Tz (centage ) Tj 2.048495 0 Td 46.432553 Tz (of ) Tj 0.688294 0 Td 49.710145 Tz (amino ) Tj 1.720736 0 Td 41.652731 Tz (acid ) Tj 1.196321 0 Td 16.38796 Tz ( ) Tj 0.147492 0 Td 41.243032 Tz (identities ) Tj 2.523746 0 Td 16.38796 Tz (. ) Tj 0.147492 0 Td 16.38796 Tz ( ) Tj 0.262207 0 Td 54.626533 Tz (As ) Tj 0.852174 0 Td 47.115385 Tz (used ) Tj 1.294649 0 Td 40.059457 Tz (herein ) Tj 1.507692 0 Td 24.58194 Tz (, ) Tj 0.360535 0 Td 49.710145 Tz (where ) Tj 1.704348 0 Td 40.9699 Tz (a ) Tj 59.220779 0 0 59.220779 0 2665.232289 Tm 5.437281 0 Td 52.065058 Tz (by ) Tj 0.776754 0 Td 42.214912 Tz (a ) Tj 0.388377 0 Td 43.019006 Tz (protein ) Tj 1.941886 0 Td 49.853801 Tz (encoded ) Tj 2.228947 0 Td 50.657895 Tz (by ) Tj 0.79364 0 Td 62.853314 Tz (SEQ ) Tj 1.300219 0 Td 52.065058 Tz (ID ) Tj 0.776754 0 Td 74.579678 Tz (NO ) Tj 0.9625 0 Td 11.25731 Tz (: ) Tj 0.202632 0 Td 28.143275 Tz (1 ) Tj 0.388377 0 Td 48.781676 Tz (and ) Tj 0.979386 0 Td 19.700292 Tz (/ ) Tj 0.151974 0 Td 39.400585 Tz (or ) Tj 0.624781 0 Td 63.791423 Tz (SEQ ) Tj 1.317105 0 Td 52.065058 Tz (ID ) Tj 0.776754 0 Td 74.579678 Tz (NO ) Tj 0.9625 0 Td 11.25731 Tz (: ) Tj 0.135088 0 Td 45.02924 Tz (2 ) Tj 0.354605 0 Td 11.25731 Tz (. ) Tj 1.401535 0 Td 47.139985 Tz (sequence ) Tj 2.532895 0 Td 30.957602 Tz (is ) Tj 0.641667 0 Td 44.225146 Tz (defined ) Tj 2.09386 0 Td 40.807749 Tz (as ) Tj 0.742982 0 Td 46.154971 Tz (being ) Tj 1.654825 0 Td 19.700292 Tz (" ) Tj 0.303947 0 Td 33.77193 Tz (at ) Tj 0.658553 0 Td 37.711988 Tz (least ) Tj 1.367763 0 Td 70.358187 Tz (X ) Tj 0.709211 0 Td 81.615497 Tz (% ) Tj 0.810526 0 Td 39.400585 Tz (identical ) Tj 2.144518 0 Td 33.77193 Tz ( ) Tj 0.472807 0 Td 37.993421 Tz (to ) Tj 0.742982 0 Td 42.214912 Tz (a ) Tj 62.608696 0 0 62.608696 0 2622.391137 Tm 5.159028 0 Td 50.578704 Tz (The ) Tj 1.086111 0 Td 43.923611 Tz (degree ) Tj 1.756944 0 Td 45.25463 Tz (of ) Tj 0.670833 0 Td 57.233796 Tz (FHB1 ) Tj 1.613194 0 Td 36.935764 Tz (activity ) Tj 1.964583 0 Td 42.296811 Tz (conferred ) Tj 2.427778 0 Td 49.247685 Tz (by ) Tj 0.782639 0 Td 46.585648 Tz (an ) Tj 0.734722 0 Td 56.568287 Tz (FHB1 ) Tj 1.597222 0 Td 40.691138 Tz (protein ) Tj 2.906944 0 Td 40.817901 Tz (reference ) Tj 2.44375 0 Td 44.921875 Tz (sequence ) Tj 2.172222 0 Td 18.634259 Tz (, ) Tj 0.351389 0 Td 33.940972 Tz (e.g. ) Tj 0.878472 0 Td 13.310185 Tz (, ) Tj 0.335417 0 Td 23.958333 Tz ( ) Tj 0.383333 0 Td 18.634259 Tz (a ) Tj 0.319444 0 Td 42.592593 Tz (polypeptide ) Tj 3.034722 0 Td 34.606481 Tz (at ) Tj 0.638889 0 Td 35.671296 Tz (least ) Tj 1.29375 0 Td 46.585648 Tz (90 ) Tj 0.590972 0 Td 77.199074 Tz (% ) Tj 0.71875 0 Td 51.909722 Tz (iden ) Tj 60 0 0 60 0 2579.348637 Tm 5.383333 0 Td 43.055556 Tz (or ) Tj 0.783333 0 Td 59.722222 Tz (FHB1 ) Tj 1.783333 0 Td 42.460317 Tz (nucleic ) Tj 2.083333 0 Td 43.055556 Tz (acid ) Tj 1.316667 0 Td 47.222222 Tz (of ) Tj 0.766667 0 Td 41.666667 Tz (the ) Tj 1.05 0 Td 43.518519 Tz (invention ) Tj 2.633333 0 Td 47.222222 Tz (can ) Tj 1.116667 0 Td 41.666667 Tz (vary ) Tj 1.083333 0 Td 19.444444 Tz (, ) Tj 0.416667 0 Td 50 Tz (and ) Tj 1.15 0 Td 42.592593 Tz (the ) Tj 2.033333 0 Td 35 Tz (tical ) Tj 1.316667 0 Td 38.888889 Tz (to ) Tj 0.766667 0 Td 62.962963 Tz (SEQ ) Tj 1.416667 0 Td 51.388889 Tz (ID ) Tj 0.883333 0 Td 65.277778 Tz (NO ) Tj 0.933333 0 Td 33.333333 Tz (: ) Tj 0.2 0 Td 33.333333 Tz (3 ) Tj 0.283333 0 Td 33.333333 Tz (, ) Tj 0.15 0 Td 33.333333 Tz (" ) Tj 0.516667 0 Td 26.388889 Tz (it ) Tj 0.6 0 Td 30.555556 Tz (is ) Tj 0.633333 0 Td 38.888889 Tz (to ) Tj 0.733333 0 Td 48.611111 Tz (be ) Tj 0.833333 0 Td 46.388889 Tz (understood ) Tj 3.033333 0 Td 38.194444 Tz (that ) Tj 1.2 0 Td 22.222222 Tz ( ) Tj 0.416667 0 Td 44.444444 Tz (X ) Tj 0.55 0 Td 80.555556 Tz (% ) Tj 57.142857 0 0 57.142857 0 2540.683544 Tm 5.6525 0 Td 45.694444 Tz (invention ) Tj 2.8 0 Td 47.152778 Tz (contemplates ) Tj 3.7625 0 Td 62.708333 Tz (FHB1 ) Tj 1.9075 0 Td 43.385417 Tz (proteins ) Tj 2.4325 0 Td 52.5 Tz (and ) Tj 1.2425 0 Td 44.583333 Tz (nucleic ) Tj 2.2225 0 Td 43.75 Tz (acids ) Tj 1.785 0 Td 36.458333 Tz (10 ) Tj 0.8925 0 Td 43.75 Tz (identical ) Tj 2.415 0 Td 17.5 Tz ( ) Tj 0.3675 0 Td 40.347222 Tz (refers ) Tj 1.7325 0 Td 40.833333 Tz (to ) Tj 0.7875 0 Td 44.84375 Tz (absolute ) Tj 2.415 0 Td 45.416667 Tz (percent ) Tj 2.1875 0 Td 39.375 Tz (identity ) Tj 1.9075 0 Td 29.166667 Tz (, ) Tj 0.455 0 Td 44.722222 Tz (unless ) Tj 1.925 0 Td 49.583333 Tz (other ) Tj 57.639752 0 0 57.639752 0 2499.744898 Tm 5.586422 0 Td 48.67397 Tz (having ) Tj 1.977802 0 Td 62.167744 Tz (FHB1 ) Tj 1.786961 0 Td 40.119881 Tz (activity ) Tj 2.151293 0 Td 42.546695 Tz (greater ) Tj 1.977802 0 Td 44.095726 Tz (than ) Tj 1.075647 0 Td 26.023707 Tz (, ) Tj 0.416379 0 Td 44.818606 Tz (or ) Tj 0.746013 0 Td 38.31268 Tz (less ) Tj 1.145043 0 Td 44.818606 Tz (than ) Tj 1.110345 0 Td 26.023707 Tz (, ) Tj 0.364332 0 Td 43.372845 Tz (the ) Tj 0.988901 0 Td 44.198994 Tz (protein ) Tj 3.157543 0 Td 49.155891 Tz (wise ) Tj 1.387931 0 Td 44.015405 Tz (indicated ) Tj 2.41153 0 Td 11.566092 Tz (. ) Tj 0.312284 0 Td 44.818606 Tz (In ) Tj 0.728664 0 Td 43.951149 Tz (cases ) Tj 1.526724 0 Td 52.625718 Tz (where ) Tj 1.786961 0 Td 50.601652 Tz (an ) Tj 0.79806 0 Td 46.264368 Tz (optimal ) Tj 2.168642 0 Td 47.549489 Tz (alignment ) Tj 2.775862 0 Td 49.155891 Tz (of ) Tj 0.711315 0 Td 52.047414 Tz (two ) Tj 57.44898 0 0 57.44898 0 2457.102669 Tm 5.62238 0 Td 51.391356 Tz (encoded ) Tj 2.419538 0 Td 53.670811 Tz (by ) Tj 0.957371 0 Td 65.758832 Tz (SEQ ) Tj 1.479574 0 Td 55.121374 Tz (ID ) Tj 0.939964 0 Td 76.879811 Tz (NO ) Tj 0.992185 0 Td 11.6045 Tz (: ) Tj 0.156661 0 Td 43.516874 Tz (3 ) Tj 0.348135 0 Td 14.505625 Tz (, ) Tj 0.417762 0 Td 43.516874 Tz (so ) Tj 0.835524 0 Td 47.14328 Tz (long ) Tj 1.427353 0 Td 42.066311 Tz (as ) Tj 0.80071 0 Td 43.516874 Tz (the ) Tj 1.061812 0 Td 43.93132 Tz (protein ) Tj 2.14103 0 Td 50.286165 Tz (and ) Tj 0.992185 0 Td 20.307874 Tz (/ ) Tj 0.156661 0 Td 42.066311 Tz (or ) Tj 1.827709 0 Td 47.707388 Tz (sequences ) Tj 2.819893 0 Td 43.154233 Tz (requires ) Tj 2.315098 0 Td 43.516874 Tz (the ) Tj 1.026998 0 Td 41.905138 Tz (insertion ) Tj 2.489165 0 Td 49.319124 Tz (of ) Tj 0.765897 0 Td 43.516874 Tz (a ) Tj 0.504796 0 Td 49.319124 Tz (gap ) Tj 1.148845 0 Td 40.615749 Tz (in ) Tj 0.713677 0 Td 51.253207 Tz (one ) Tj 1.166252 0 Td 43.516874 Tz (or ) Tj 0.731083 0 Td 48.593843 Tz (both ) Tj 1.39254 0 Td 49.319124 Tz (of ) Tj 61.578947 0 0 61.578947 0 2412.818804 Tm 5.22906 0 Td 41.371591 Tz (nucleic ) Tj 1.9 0 Td 41.951567 Tz (acid ) Tj 1.120513 0 Td 42.966524 Tz (provides ) Tj 2.257265 0 Td 51.424501 Tz (some ) Tj 1.364103 0 Td 43.304843 Tz (not ) Tj 0.925641 0 Td 38.93272 Tz (insubstantial ) Tj 3.199145 0 Td 48.225848 Tz (enhancement ) Tj 3.32906 0 Td 46.011396 Tz (of ) Tj 1.721368 0 Td 40.598291 Tz (the ) Tj 0.990598 0 Td 44.808484 Tz (sequences ) Tj 2.419658 0 Td 18.945869 Tz (, ) Tj 0.373504 0 Td 47.364672 Tz (an ) Tj 0.795726 0 Td 48.717949 Tz (amino ) Tj 1.721368 0 Td 41.951567 Tz (acid ) Tj 1.201709 0 Td 41.758242 Tz (residue ) Tj 1.981197 0 Td 39.245014 Tz (in ) Tj 0.682051 0 Td 47.815764 Tz (one ) Tj 1.104274 0 Td 45.673077 Tz (sequence ) Tj 2.403419 0 Td 37.891738 Tz (that ) Tj 60 0 0 60 0 2373.145777 Tm 5.383333 0 Td 42.460317 Tz (disease ) Tj 2 0 Td 40.833333 Tz (resistance ) Tj 2.666667 0 Td 38.888889 Tz (relative ) Tj 2.083333 0 Td 37.5 Tz (to ) Tj 0.716667 0 Td 41.666667 Tz (a ) Tj 0.483333 0 Td 41.269841 Tz (control ) Tj 1.966667 0 Td 42.777778 Tz (plant ) Tj 1.233333 0 Td 27.777778 Tz (. ) Tj 0.383333 0 Td 52.777778 Tz (The ) Tj 1.183333 0 Td 41.666667 Tz (extent ) Tj 1.733333 0 Td 47.222222 Tz (of ) Tj 1.783333 0 Td 40.277778 Tz (aligns ) Tj 1.766667 0 Td 46.527778 Tz (with ) Tj 1.416667 0 Td 41.666667 Tz (a ) Tj 0.566667 0 Td 47.222222 Tz (gap ) Tj 1.183333 0 Td 40.277778 Tz (in ) Tj 0.766667 0 Td 41.666667 Tz (the ) Tj 1.066667 0 Td 42.222222 Tz (other ) Tj 1.583333 0 Td 46.875 Tz (sequence ) Tj 2.566667 0 Td 30.555556 Tz (is ) Tj 0.7 0 Td 46.825397 Tz (counted ) Tj 2.266667 0 Td 38.888889 Tz (as ) Tj 0.8 0 Td 41.666667 Tz (a ) Tj 71.428571 0 0 71.428571 0 2327.164216 Tm 4.508 0 Td 34.3 Tz (resistance ) Tj 2.31 0 Td 42 Tz (can ) Tj 0.938 0 Td 38.5 Tz (vary ) Tj 1.176 0 Td 39.925926 Tz (depending ) Tj 2.352 0 Td 45.5 Tz (upon ) Tj 1.33 0 Td 35 Tz (a ) Tj 0.434 0 Td 34.666667 Tz (variety ) Tj 1.694 0 Td 39.666667 Tz (of ) Tj 0.672 0 Td 34.416667 Tz (external ) Tj 2.03 0 Td 28 Tz (15 ) Tj 0.7 0 Td 42.583333 Tz (mismatch ) Tj 2.156 0 Td 34.222222 Tz (for ) Tj 0.714 0 Td 38.208333 Tz (purposes ) Tj 1.988 0 Td 39.666667 Tz (of ) Tj 0.546 0 Td 37.969697 Tz (determining ) Tj 2.632 0 Td 36.666667 Tz (percent ) Tj 1.666 0 Td 31.791667 Tz (identity ) Tj 1.526 0 Td 23.333333 Tz (. ) Tj 0.28 0 Td 43.75 Tz (Gaps ) Tj 58.435374 0 0 58.435374 0 2290.697674 Tm 5.527474 0 Td 40.745052 Tz (factors ) Tj 1.694179 0 Td 25.669383 Tz (, ) Tj 0.342258 0 Td 44.049929 Tz (including ) Tj 2.532712 0 Td 42.782305 Tz (the ) Tj 0.906985 0 Td 46.347497 Tz (presence ) Tj 2.378696 0 Td 48.486612 Tz (of ) Tj 0.667404 0 Td 43.923166 Tz (other ) Tj 1.437485 0 Td 41.641444 Tz (resistance ) Tj 2.618277 0 Td 28.521537 Tz (- ) Tj 0.205355 0 Td 42.782305 Tz (conferring ) Tj 3.884633 0 Td 48.486612 Tz (can ) Tj 1.078114 0 Td 49.912689 Tz (be ) Tj 0.838533 0 Td 39.930151 Tz (internal ) Tj 2.173341 0 Td 44.208382 Tz (or ) Tj 0.735856 0 Td 44.208382 Tz (external ) Tj 2.019325 0 Td 25.669383 Tz (, ) Tj 0.427823 0 Td 29.947614 Tz (i.e. ) Tj 0.804307 0 Td 14.260768 Tz (, ) Tj 0.342258 0 Td 42.782305 Tz (a ) Tj 0.479162 0 Td 42.211874 Tz (truncation ) Tj 2.63539 0 Td 19.965076 Tz (. ) Tj 60.672269 0 0 60.672269 0 2250.185919 Tm 5.307202 0 Td 46.698984 Tz (genes ) Tj 1.384488 0 Td 19.228994 Tz (, ) Tj 0.41205 0 Td 41.204986 Tz (the ) Tj 1.005402 0 Td 40.027701 Tz (overall ) Tj 1.961357 0 Td 41.597415 Tz (genetic ) Tj 2.010803 0 Td 48.072484 Tz (background ) Tj 2.867867 0 Td 27.469991 Tz (, ) Tj 0.461496 0 Td 48.530317 Tz (and ) Tj 1.137258 0 Td 45.219831 Tz (environmental ) Tj 5.439058 0 Td 52.192982 Tz (The ) Tj 1.516343 0 Td 47.385734 Tz (term ) Tj 1.714127 0 Td 21.975993 Tz (" ) Tj 0.362604 0 Td 38.457987 Tz (substantial ) Tj 3.115097 0 Td 38.457987 Tz (identity ) Tj 1.977839 0 Td 27.469991 Tz ( ) Tj 0.758172 0 Td 46.698984 Tz (of ) Tj 1.07133 0 Td 43.559557 Tz (polynucleotide ) Tj 57.142857 0 0 57.142857 0 2206.344702 Tm 5.6525 0 Td 41.25 Tz (factors ) Tj 1.7675 0 Td 20.416667 Tz (. ) Tj 0.315 0 Td 45.208333 Tz (In ) Tj 0.665 0 Td 44.722222 Tz (preferred ) Tj 2.555 0 Td 52.765152 Tz (embodiments ) Tj 3.64 0 Td 53.958333 Tz (of ) Tj 0.77 0 Td 43.75 Tz (the ) Tj 0.875 0 Td 44.074074 Tz (invention ) Tj 2.415 0 Td 26.25 Tz (, ) Tj 0.3675 0 Td 49.583333 Tz (an ) Tj 0.7525 0 Td 62.708333 Tz (FHB1 ) Tj 56.326531 0 0 56.326531 0 2210.487909 Tm 23.008696 0 Td 49.31562 Tz (sequences ) Tj 3.213406 0 Td 56.811594 Tz (means ) Tj 2.272464 0 Td 41.425121 Tz (that ) Tj 1.580072 0 Td 44.384058 Tz (a ) Tj 0.83442 0 Td 46.92029 Tz (polynucleotide ) Tj 4.527174 0 Td 48.986849 Tz (comprises ) Tj 3.248913 0 Td 44.384058 Tz (a ) Tj 58.857143 0 0 58.857143 0 2169.422165 Tm 5.453883 0 Td 42.071197 Tz (protein ) Tj 2.004854 0 Td 43.419633 Tz (has ) Tj 1.019417 0 Td 42.475728 Tz (antifungal ) Tj 2.786408 0 Td 37.520227 Tz (activity ) Tj 1.76699 0 Td 28.317152 Tz (. ) Tj 0.441748 0 Td 42.475728 Tz (In ) Tj 0.713592 0 Td 40.453074 Tz (certain ) Tj 1.970874 0 Td 39.958648 Tz (preferred ) Tj 2.497573 0 Td 49.352751 Tz (embodi- ) Tj 3.381068 0 Td 47.43123 Tz (sequence ) Tj 2.531553 0 Td 39.644013 Tz (that ) Tj 1.18932 0 Td 45.307443 Tz (has ) Tj 1.087379 0 Td 36.812298 Tz (at ) Tj 0.696602 0 Td 37.944984 Tz (least ) Tj 1.393204 0 Td 48.139159 Tz (25 ) Tj 0.645631 0 Td 82.119741 Tz (% ) Tj 0.781553 0 Td 47.43123 Tz (sequence ) Tj 2.548544 0 Td 38.58212 Tz (identity ) Tj 1.817961 0 Td 28.317152 Tz (. ) Tj 0.509709 0 Td 48.139159 Tz (Alterna ) Tj 61.428571 0 0 61.428571 0 2123.619963 Tm 5.24186 0 Td 47.751938 Tz (ments ) Tj 1.611628 0 Td 40.697674 Tz (the ) Tj 0.911628 0 Td 40.697674 Tz (antifungal ) Tj 2.62093 0 Td 37.645349 Tz (activity ) Tj 1.986047 0 Td 37.306202 Tz (inhibits ) Tj 1.986047 0 Td 40.697674 Tz (a ) Tj 0.439535 0 Td 40.697674 Tz (species ) Tj 1.904651 0 Td 44.767442 Tz (of ) Tj 0.618605 0 Td 47.141473 Tz (Fusarium ) Tj 2.393023 0 Td 24.418605 Tz (, ) Tj 0.537209 0 Td 36.627907 Tz (20 ) Tj 0.846512 0 Td 37.984496 Tz (tively ) Tj 1.383721 0 Td 13.565891 Tz (, ) Tj 0.276744 0 Td 42.635659 Tz (percent ) Tj 1.969767 0 Td 38.323643 Tz (identity ) Tj 2.018605 0 Td 47.028424 Tz (can ) Tj 0.993023 0 Td 47.48062 Tz (be ) Tj 0.765116 0 Td 47.028424 Tz (any ) Tj 1.04186 0 Td 39.922481 Tz (integer ) Tj 1.839535 0 Td 48.837209 Tz (from ) Tj 1.351163 0 Td 35.271318 Tz (at ) Tj 0.602326 0 Td 36.356589 Tz (least ) Tj 1.286047 0 Td 44.767442 Tz (25 ) Tj 0.602326 0 Td 78.682171 Tz (% ) Tj 59.557823 0 0 59.557823 0 2081.570451 Tm 5.423301 0 Td 35.679612 Tz (e.g. ) Tj 0.923472 0 Td 13.992005 Tz (, ) Tj 0.335808 0 Td 41.976014 Tz (a ) Tj 0.470131 0 Td 41.976014 Tz (species ) Tj 1.998058 0 Td 41.626214 Tz (selected ) Tj 2.199543 0 Td 50.371216 Tz (from ) Tj 1.376813 0 Td 36.379212 Tz (F. ) Tj 0.671616 0 Td 51.61495 Tz (avenaceum ) Tj 2.820788 0 Td 13.992005 Tz (, ) Tj 0.319018 0 Td 36.379212 Tz (F. ) Tj 0.688407 0 Td 46.873215 Tz (bubigeum ) Tj 2.384238 0 Td 27.984009 Tz (, ) Tj 0.40297 0 Td 37.778412 Tz (F. ) Tj 1.746202 0 Td 37.778412 Tz (to ) Tj 0.688407 0 Td 47.572816 Tz (100 ) Tj 0.889891 0 Td 81.153626 Tz (% ) Tj 0.654826 0 Td 27.984009 Tz (\( ) Tj 0.201485 0 Td 40.110413 Tz (e.g ) Tj 0.789149 0 Td 11.193604 Tz (. ) Tj 0.134323 0 Td 13.992005 Tz (, ) Tj 0.319018 0 Td 33.580811 Tz (at ) Tj 0.587664 0 Td 38.617933 Tz (least ) Tj 1.292861 0 Td 43.375214 Tz (25 ) Tj 0.654826 0 Td 33.580811 Tz (% ) Tj 0.41976 0 Td 33.580811 Tz (, ) Tj 0.285437 0 Td 48.972016 Tz (26 ) Tj 0.621245 0 Td 81.153626 Tz (% ) Tj 0.537293 0 Td 13.992005 Tz (, ) Tj 0.268646 0 Td 48.972016 Tz (27 ) Tj 0.638035 0 Td 81.153626 Tz (% ) Tj 0.537293 0 Td 13.992005 Tz (, ) Tj 0.268646 0 Td 47.572816 Tz (28 ) Tj 0.621245 0 Td 81.153626 Tz (% ) Tj 0.537293 0 Td 13.992005 Tz (, ) Tj 0.302227 0 Td 35.446412 Tz (... ) Tj 0.83952 0 Td 13.992005 Tz (, ) Tj 0.268646 0 Td 48.972016 Tz (70 ) Tj 0.621245 0 Td 81.153626 Tz (% ) Tj 0.537293 0 Td 13.992005 Tz (, ) Tj 0.268646 0 Td 44.774415 Tz (71 ) Tj 0.621245 0 Td 81.153626 Tz (% ) Tj 0.554083 0 Td 13.992005 Tz (, ) Tj 58.639456 0 0 58.639456 0 2040.271072 Tm 5.508237 0 Td 49.383701 Tz (culmorum ) Tj 2.540951 0 Td 25.580046 Tz (, ) Tj 0.324014 0 Td 36.948956 Tz (F. ) Tj 0.596868 0 Td 52.452014 Tz (graminearum ) Tj 3.49594 0 Td 14.211137 Tz (, ) Tj 0.289907 0 Td 36.948956 Tz (F. ) Tj 0.648028 0 Td 43.925332 Tz (langsethiae ) Tj 2.830858 0 Td 28.422274 Tz (, ) Tj 0.375174 0 Td 38.37007 Tz (F. ) Tj 0.648028 0 Td 47.686259 Tz (oxysporum ) Tj 2.779698 0 Td 19.895592 Tz (, ) Tj 0.289907 0 Td 39.791183 Tz (F. ) Tj 1.790603 0 Td 49.738979 Tz (72 ) Tj 0.630974 0 Td 82.424594 Tz (% ) Tj 0.562761 0 Td 14.211137 Tz (, ) Tj 0.358121 0 Td 48.317865 Tz (73 ) Tj 0.630974 0 Td 82.424594 Tz (% ) Tj 0.562761 0 Td 14.211137 Tz (, ) Tj 0.358121 0 Td 49.738979 Tz (74 ) Tj 0.648028 0 Td 82.424594 Tz (% ) Tj 0.545708 0 Td 14.211137 Tz (, ) Tj 0.358121 0 Td 48.317865 Tz (75 ) Tj 0.648028 0 Td 82.424594 Tz (% ) Tj 0.545708 0 Td 14.211137 Tz (, ) Tj 0.358121 0 Td 49.738979 Tz (76 ) Tj 0.648028 0 Td 82.424594 Tz (% ) Tj 0.545708 0 Td 14.211137 Tz (, ) Tj 0.375174 0 Td 48.317865 Tz (77 ) Tj 0.630974 0 Td 82.424594 Tz (% ) Tj 0.545708 0 Td 14.211137 Tz (, ) Tj 0.375174 0 Td 48.317865 Tz (78 ) Tj 0.630974 0 Td 82.424594 Tz (% ) Tj 0.545708 0 Td 14.211137 Tz (, ) Tj 0.375174 0 Td 49.738979 Tz (79 ) Tj 0.630974 0 Td 82.424594 Tz (% ) Tj 0.545708 0 Td 14.211137 Tz (, ) Tj 0.392227 0 Td 49.738979 Tz (80 ) Tj 0.613921 0 Td 82.424594 Tz (% ) Tj 0.562761 0 Td 14.211137 Tz (, ) Tj 0.375174 0 Td 44.054524 Tz (81 ) Tj 0.613921 0 Td 82.424594 Tz (% ) Tj 0.562761 0 Td 14.211137 Tz (, ) Tj 56.027875 0 0 56.027875 0 1999.346365 Tm 5.657898 0 Td 56.519486 Tz (poae ) Tj 1.374316 0 Td 14.873549 Tz (, ) Tj 0.446206 0 Td 38.671227 Tz (F. ) Tj 0.82102 0 Td 45.550244 Tz (sporotrichioides ) Tj 4.30143 0 Td 29.747098 Tz (, ) Tj 0.499751 0 Td 38.671227 Tz (F. ) Tj 0.82102 0 Td 44.918118 Tz (tricinctum ) Tj 2.730784 0 Td 14.873549 Tz (, ) Tj 0.464055 0 Td 38.671227 Tz (F. ) Tj 0.82102 0 Td 40.654367 Tz (verticillioides ) Tj 3.623197 0 Td 26.772388 Tz (, ) Tj 1.606343 0 Td 50.570066 Tz (82 ) Tj 0.642537 0 Td 86.266584 Tz (% ) Tj 0.588993 0 Td 14.873549 Tz (, ) Tj 0.392662 0 Td 49.082711 Tz (83 ) Tj 0.642537 0 Td 86.266584 Tz (% ) Tj 0.588993 0 Td 14.873549 Tz (, ) Tj 0.392662 0 Td 50.570066 Tz (84 ) Tj 0.660386 0 Td 86.266584 Tz (% ) Tj 0.571144 0 Td 14.873549 Tz (, ) Tj 0.392662 0 Td 49.082711 Tz (85 ) Tj 0.660386 0 Td 86.266584 Tz (% ) Tj 0.571144 0 Td 14.873549 Tz (, ) Tj 0.392662 0 Td 50.570066 Tz (86 ) Tj 0.660386 0 Td 86.266584 Tz (% ) Tj 0.571144 0 Td 14.873549 Tz (, ) Tj 0.41051 0 Td 49.082711 Tz (87 ) Tj 0.642537 0 Td 86.266584 Tz (% ) Tj 0.571144 0 Td 14.873549 Tz (, ) Tj 0.41051 0 Td 49.082711 Tz (88 ) Tj 0.642537 0 Td 86.266584 Tz (% ) Tj 0.571144 0 Td 14.873549 Tz (, ) Tj 0.41051 0 Td 50.570066 Tz (89 ) Tj 0.642537 0 Td 86.266584 Tz (% ) Tj 0.571144 0 Td 14.873549 Tz (, ) Tj 0.41051 0 Td 52.057421 Tz (90 ) Tj 0.642537 0 Td 86.266584 Tz (% ) Tj 0.588993 0 Td 14.873549 Tz (, ) Tj 0.392662 0 Td 46.108002 Tz (91 ) Tj 0.642537 0 Td 86.266584 Tz (% ) Tj 0.588993 0 Td 14.873549 Tz (, ) Tj 58.928571 0 0 58.928571 0 1961.71223 Tm 5.481212 0 Td 49.023569 Tz (and ) Tj 1.10303 0 Td 36.767677 Tz (F. ) Tj 0.695758 0 Td 44.781145 Tz (virguliforme ) Tj 3.088485 0 Td 28.282828 Tz (. ) Tj 60 0 0 60 0 1954 Tm 21.633333 0 Td 47.222222 Tz (92 ) Tj 0.6 0 Td 80.555556 Tz (% ) Tj 0.55 0 Td 13.888889 Tz (, ) Tj 0.3 0 Td 45.833333 Tz (93 ) Tj 0.6 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.316667 0 Td 45.833333 Tz (94 ) Tj 0.6 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.316667 0 Td 44.444444 Tz (95 ) Tj 0.6 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.3 0 Td 47.222222 Tz (96 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.3 0 Td 47.222222 Tz (97 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.3 0 Td 47.222222 Tz (98 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.3 0 Td 47.222222 Tz (99 ) Tj 0.6 0 Td 80.555556 Tz (% ) Tj 0.55 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 47.222222 Tz (100 ) Tj 0.883333 0 Td 80.555556 Tz (% ) Tj 0.516667 0 Td 27.777778 Tz (\) ) Tj 0.25 0 Td 11.111111 Tz (. ) Tj 0.283333 0 Td 56.944444 Tz (Some ) Tj 60 0 0 60 0 1915.06045 Tm 6.016667 0 Td 41.666667 Tz (In ) Tj 0.65 0 Td 42.222222 Tz (cases ) Tj 1.433333 0 Td 50.555556 Tz (where ) Tj 1.666667 0 Td 41.666667 Tz (a ) Tj 0.4 0 Td 44.047619 Tz (polynucleotide ) Tj 3.883333 0 Td 46.527778 Tz (sequence ) Tj 2.4 0 Td 47.222222 Tz (of ) Tj 0.633333 0 Td 41.666667 Tz (the ) Tj 0.916667 0 Td 43.518519 Tz (invention ) Tj 2.733333 0 Td 36.111111 Tz (25 ) Tj 0.883333 0 Td 50.252525 Tz (embodiments ) Tj 3.55 0 Td 42.857143 Tz (include ) Tj 2.016667 0 Td 36.111111 Tz (at ) Tj 0.65 0 Td 37.222222 Tz (least ) Tj 1.166667 0 Td 11.111111 Tz (: ) Tj 0.333333 0 Td 47.222222 Tz (25 ) Tj 0.633333 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.316667 0 Td 50 Tz (30 ) Tj 0.633333 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 45.833333 Tz (35 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 50 Tz (40 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.55 0 Td 13.888889 Tz (, ) Tj 0.3 0 Td 54.166667 Tz (45 ) Tj 0.75 0 Td 33.333333 Tz (% ) Tj 0.5 0 Td 30.555556 Tz (, ) Tj 57.785714 0 0 57.785714 0 1873.667116 Tm 5.589617 0 Td 31.726411 Tz (is ) Tj 0.657602 0 Td 43.52549 Tz (transcribed ) Tj 3.132262 0 Td 50.954539 Tz (and ) Tj 1.159456 0 Td 42.1096 Tz (translated ) Tj 2.751545 0 Td 38.936959 Tz (to ) Tj 0.744129 0 Td 49.443758 Tz (produce ) Tj 2.336218 0 Td 43.263288 Tz (a ) Tj 0.536465 0 Td 42.974866 Tz (functional ) Tj 2.889988 0 Td 43.840132 Tz (poly- ) Tj 2.665019 0 Td 50.473836 Tz (50 ) Tj 0.622991 0 Td 83.642357 Tz (% ) Tj 0.571075 0 Td 14.421096 Tz (, ) Tj 0.311496 0 Td 46.147507 Tz (55 ) Tj 0.622991 0 Td 83.642357 Tz (% ) Tj 0.55377 0 Td 14.421096 Tz (, ) Tj 0.311496 0 Td 50.473836 Tz (60 ) Tj 0.640297 0 Td 83.642357 Tz (% ) Tj 0.55377 0 Td 14.421096 Tz (, ) Tj 0.311496 0 Td 47.589617 Tz (65 ) Tj 0.622991 0 Td 83.642357 Tz (% ) Tj 0.571075 0 Td 14.421096 Tz (, ) Tj 0.29419 0 Td 50.473836 Tz (70 ) Tj 0.640297 0 Td 83.642357 Tz (% ) Tj 0.55377 0 Td 14.421096 Tz (, ) Tj 0.29419 0 Td 49.031726 Tz (75 ) Tj 0.657602 0 Td 83.642357 Tz (% ) Tj 0.55377 0 Td 14.421096 Tz (, ) Tj 0.311496 0 Td 50.473836 Tz (80 ) Tj 0.640297 0 Td 83.642357 Tz (% ) Tj 0.55377 0 Td 14.421096 Tz (, ) Tj 0.311496 0 Td 46.147507 Tz (85 ) Tj 0.622991 0 Td 83.642357 Tz (% ) Tj 0.55377 0 Td 14.421096 Tz (, ) Tj 0.311496 0 Td 50.473836 Tz (90 ) Tj 0.640297 0 Td 83.642357 Tz (% ) Tj 0.55377 0 Td 14.421096 Tz (, ) Tj 0.311496 0 Td 47.589617 Tz (95 ) Tj 0.640297 0 Td 83.642357 Tz (% ) Tj 0.55377 0 Td 14.421096 Tz (, ) Tj 0.29419 0 Td 44.705398 Tz (or ) Tj 60.816327 0 0 60.816327 0 1833.419228 Tm 5.278188 0 Td 42.281879 Tz (peptide ) Tj 1.775839 0 Td 27.404922 Tz (, ) Tj 0.44396 0 Td 47.501864 Tz (one ) Tj 1.118121 0 Td 46.588367 Tz (of ) Tj 0.772819 0 Td 33.434004 Tz (skill ) Tj 1.249664 0 Td 39.052013 Tz (will ) Tj 1.200336 0 Td 44.152374 Tz (recognize ) Tj 2.61443 0 Td 38.36689 Tz (that ) Tj 1.16745 0 Td 46.196868 Tz (because ) Tj 2.186913 0 Td 46.588367 Tz (of ) Tj 0.756376 0 Td 49.876957 Tz (codon ) Tj 2.778859 0 Td 46.588367 Tz (99 ) Tj 0.591946 0 Td 79.474273 Tz (% ) Tj 0.756376 0 Td 38.709452 Tz (identity ) Tj 2.137584 0 Td 50.013982 Tz (compared ) Tj 2.647315 0 Td 36.996644 Tz (to ) Tj 0.739933 0 Td 41.107383 Tz (a ) Tj 0.493289 0 Td 42.325379 Tz (reference ) Tj 2.581544 0 Td 45.903244 Tz (sequence ) Tj 2.466443 0 Td 43.847875 Tz (using ) Tj 1.562081 0 Td 42.02088 Tz (the ) Tj 60.571429 0 0 60.571429 0 1793.272844 Tm 5.332547 0 Td 46.501572 Tz (degeneracy ) Tj 3.186321 0 Td 41.273585 Tz (a ) Tj 0.627358 0 Td 52.279874 Tz (number ) Tj 2.261792 0 Td 46.77673 Tz (of ) Tj 0.875 0 Td 43.435535 Tz (polynucleotide ) Tj 4.061321 0 Td 45.248078 Tz (sequences ) Tj 2.839623 0 Td 39.209906 Tz (will ) Tj 2.195755 0 Td 48.152516 Tz (programs ) Tj 2.575472 0 Td 43.413697 Tz (described ) Tj 2.591981 0 Td 39.897799 Tz (herein ) Tj 1.535377 0 Td 24.764151 Tz (; ) Tj 0.412736 0 Td 42.099057 Tz (preferably ) Tj 2.773585 0 Td 64.386792 Tz (BLAST ) Tj 2.162736 0 Td 44.575472 Tz (using ) Tj 1.683962 0 Td 46.088836 Tz (stan ) Tj 62.180451 0 0 62.180451 0 1748.891743 Tm 5.194559 0 Td 46.459761 Tz (encode ) Tj 1.833374 0 Td 40.205562 Tz (the ) Tj 0.900605 0 Td 49.58686 Tz (same ) Tj 1.350907 0 Td 43.129603 Tz (polypeptide ) Tj 2.782225 0 Td 26.803708 Tz (. ) Tj 0.353809 0 Td 46.638452 Tz (These ) Tj 1.559976 0 Td 38.865377 Tz (variants ) Tj 2.058525 0 Td 39.312105 Tz (are ) Tj 0.884522 0 Td 37.525191 Tz (specifically ) Tj 3.940145 0 Td 44.226119 Tz (dard ) Tj 1.238331 0 Td 44.226119 Tz (parameters ) Tj 2.637485 0 Td 24.123337 Tz (, ) Tj 0.337727 0 Td 38.865377 Tz (as ) Tj 0.691536 0 Td 42.290295 Tz (described ) Tj 2.46058 0 Td 48.782749 Tz (below ) Tj 1.479565 0 Td 10.721483 Tz (. ) Tj 0.28948 0 Td 50.927046 Tz (The ) Tj 1.109674 0 Td 40.971383 Tz (present ) Tj 1.929867 0 Td 41.694657 Tz (invention ) Tj 62.857143 0 0 62.857143 0 1707.16677 Tm 5.138636 0 Td 44.69697 Tz (covered ) Tj 2.004545 0 Td 49.05303 Tz (by ) Tj 0.731818 0 Td 40.656566 Tz (the ) Tj 0.875 0 Td 43.484848 Tz (terms ) Tj 1.479545 0 Td 15.909091 Tz ( ) Tj 0.143182 0 Td 52.367424 Tz (Fhbl ) Tj 1.463636 0 Td 40.530303 Tz (nucleic ) Tj 1.877273 0 Td 38.44697 Tz (acid ) Tj 0.986364 0 Td 23.863636 Tz (, ) Tj 0.254545 0 Td 23.863636 Tz ( ) Tj 0.302273 0 Td 15.909091 Tz ( ) Tj 0.143182 0 Td 52.367424 Tz (Fhb1 ) Tj 1.463636 0 Td 42.159091 Tz (polynucle- ) Tj 2.927273 0 Td 35.795455 Tz (30 ) Tj 0.827273 0 Td 42.092803 Tz (provides ) Tj 2.290909 0 Td 38.888889 Tz (for ) Tj 0.922727 0 Td 41.540404 Tz (polynucleotides ) Tj 3.993182 0 Td 37.121212 Tz (that ) Tj 1.145455 0 Td 38.888889 Tz (are ) Tj 0.954545 0 Td 34.469697 Tz (at ) Tj 0.668182 0 Td 35.530303 Tz (least ) Tj 1.336364 0 Td 37.937063 Tz (substantially ) Tj 58.801843 0 0 58.801843 0 1666.092308 Tm 5.493025 0 Td 42.515674 Tz (otide ) Tj 1.258464 0 Td 34.012539 Tz ( ) Tj 0.510188 0 Td 51.018809 Tz (and ) Tj 1.122414 0 Td 39.11442 Tz (their ) Tj 1.394514 0 Td 43.031015 Tz (equivalents ) Tj 2.840047 0 Td 28.343783 Tz (. ) Tj 0.442163 0 Td 42.515674 Tz (In ) Tj 0.748276 0 Td 41.807079 Tz (addition ) Tj 2.040752 0 Td 25.509404 Tz (, ) Tj 0.40815 0 Td 42.515674 Tz (the ) Tj 0.986364 0 Td 46.483804 Tz (terms ) Tj 1.734639 0 Td 37.909809 Tz (specifi- ) Tj 3.078135 0 Td 39.681296 Tz (identical ) Tj 2.41489 0 Td 39.681296 Tz (to ) Tj 0.782288 0 Td 63.301115 Tz (SEQ ) Tj 1.428527 0 Td 52.435998 Tz (ID ) Tj 0.901332 0 Td 75.111024 Tz (NO ) Tj 0.969357 0 Td 11.337513 Tz (: ) Tj 0.187069 0 Td 28.343783 Tz (1 ) Tj 0.289107 0 Td 14.171891 Tz (, ) Tj 0.391144 0 Td 45.350052 Tz (2 ) Tj 0.323119 0 Td 14.171891 Tz (, ) Tj 0.391144 0 Td 45.350052 Tz (4 ) Tj 0.340125 0 Td 14.171891 Tz (, ) Tj 0.40815 0 Td 39.681296 Tz (5 ) Tj 0.544201 0 Td 42.515674 Tz (or ) Tj 0.782288 0 Td 34.012539 Tz (6. ) Tj 0.714263 0 Td 56.687565 Tz (One ) Tj 1.292476 0 Td 48.184431 Tz (of ) Tj 0.799295 0 Td 34.579415 Tz (skill ) Tj 1.309483 0 Td 40.38989 Tz (will ) Tj 67.142857 0 0 67.142857 0 1621.900123 Tm 4.810638 0 Td 35.248227 Tz (cally ) Tj 1.23617 0 Td 38.652482 Tz (include ) Tj 1.787234 0 Td 38.723404 Tz (those ) Tj 1.340426 0 Td 32.890071 Tz (full ) Tj 1.02766 0 Td 35.165485 Tz (length ) Tj 1.474468 0 Td 40.819543 Tz (sequences ) Tj 2.412766 0 Td 35.515548 Tz (substantially ) Tj 2.948936 0 Td 39.219858 Tz (iden- ) Tj 2.26383 0 Td 39.99212 Tz (recognize ) Tj 2.323404 0 Td 34.751773 Tz (that ) Tj 0.982979 0 Td 38.22695 Tz (these ) Tj 1.310638 0 Td 39.3026 Tz (values ) Tj 1.593617 0 Td 42.198582 Tz (can ) Tj 0.908511 0 Td 43.439716 Tz (be ) Tj 0.7 0 Td 37.806874 Tz (appropriately ) Tj 3.12766 0 Td 38.475177 Tz (adjusted ) Tj 1.93617 0 Td 39.716312 Tz (to ) Tj 57.983193 0 0 57.983193 0 1583.507292 Tm 5.553333 0 Td 36.217391 Tz (tical ) Tj 1.37971 0 Td 48.864734 Tz (and ) Tj 0.983043 0 Td 20.120773 Tz (/ ) Tj 0.120725 0 Td 45.990338 Tz (or ) Tj 0.827826 0 Td 41.347083 Tz (substantially ) Tj 3.518261 0 Td 42.294686 Tz (similar ) Tj 2.052319 0 Td 37.36715 Tz (\( ) Tj 0.275942 0 Td 46.852657 Tz (determined ) Tj 3.087101 0 Td 40.241546 Tz (as ) Tj 0.793333 0 Td 45.670961 Tz (described ) Tj 3.776957 0 Td 47.267848 Tz (determine ) Tj 2.880145 0 Td 47.095875 Tz (corresponding ) Tj 4.001159 0 Td 40.600845 Tz (identity ) Tj 2.276522 0 Td 48.864734 Tz (of ) Tj 0.827826 0 Td 42.756643 Tz (proteins ) Tj 2.397246 0 Td 50.917874 Tz (encoded ) Tj 2.448986 0 Td 51.73913 Tz (by ) Tj 59.84127 0 0 59.84127 0 1541.673114 Tm 5.380902 0 Td 50.689655 Tz (below ) Tj 1.554111 0 Td 27.851459 Tz (\) ) Tj 0.350928 0 Td 37.599469 Tz (to ) Tj 0.651724 0 Td 48.740053 Tz (an ) Tj 0.751989 0 Td 50.132626 Tz (Fhb1 ) Tj 1.437135 0 Td 44.164456 Tz (polynucleotide ) Tj 3.910345 0 Td 46.999337 Tz (sequence ) Tj 2.439788 0 Td 49.204244 Tz (and ) Tj 1.036074 0 Td 38.992042 Tz (that ) Tj 1.119629 0 Td 48.740053 Tz (encode ) Tj 3.024668 0 Td 50.132626 Tz (two ) Tj 1.270027 0 Td 43.169761 Tz (nucleotide ) Tj 2.957825 0 Td 45.800177 Tz (sequences ) Tj 2.840849 0 Td 50.132626 Tz (by ) Tj 0.95252 0 Td 42.70557 Tz (taking ) Tj 1.90504 0 Td 38.295756 Tz (into ) Tj 1.303448 0 Td 45.755968 Tz (account ) Tj 2.272679 0 Td 50.132626 Tz (codon ) Tj 62.857143 0 0 62.857143 0 1500.304454 Tm 5.122727 0 Td 39.441288 Tz (proteins ) Tj 2.195455 0 Td 37.121212 Tz (that ) Tj 1.161364 0 Td 38.005051 Tz (retain ) Tj 1.638636 0 Td 39.772727 Tz (the ) Tj 1.018182 0 Td 41.098485 Tz (function ) Tj 2.259091 0 Td 43.75 Tz (of ) Tj 0.747727 0 Td 39.772727 Tz (the ) Tj 1.018182 0 Td 47.19697 Tz (FHB1polypeptide ) Tj 4.629545 0 Td 34.469697 Tz (35 ) Tj 0.843182 0 Td 44.015152 Tz (degeneracy ) Tj 2.656818 0 Td 26.515152 Tz (, ) Tj 0.286364 0 Td 48.257576 Tz (amino ) Tj 1.606818 0 Td 41.098485 Tz (acid ) Tj 1.145455 0 Td 35.795455 Tz (similarity ) Tj 2.163636 0 Td 26.515152 Tz (, ) Tj 0.318182 0 Td 42.045455 Tz (reading ) Tj 1.925 0 Td 45.075758 Tz (frame ) Tj 1.495455 0 Td 40.495868 Tz (positioning ) Tj 54.945055 0 0 54.945055 0 1459.340285 Tm 5.8786 0 Td 30.333333 Tz (\( ) Tj 0.2184 0 Td 37.916667 Tz (e.g. ) Tj 1.001 0 Td 15.166667 Tz (, ) Tj 0.4914 0 Td 43.477778 Tz (resulting ) Tj 2.8028 0 Td 46.258333 Tz (from ) Tj 1.6016 0 Td 47.522222 Tz (conservative ) Tj 3.822 0 Td 43.4 Tz (substitutions ) Tj 3.7674 0 Td 51.566667 Tz (of ) Tj 0.9282 0 Td 55.206667 Tz (amino ) Tj 3.094 0 Td 53.588889 Tz (and ) Tj 1.183 0 Td 46.511111 Tz (the ) Tj 1.092 0 Td 40.95 Tz (like ) Tj 1.0556 0 Td 12.133333 Tz (. ) Tj 58.571429 0 0 58.571429 0 1418.541371 Tm 5.514634 0 Td 42.113821 Tz (acids ) Tj 1.519512 0 Td 41.260163 Tz (in ) Tj 0.717073 0 Td 41.734417 Tz (the ) Tj 0.990244 0 Td 61.178862 Tz (FHB1 ) Tj 1.758537 0 Td 45.528455 Tz (polypeptide ) Tj 3.039024 0 Td 28.455285 Tz (\) ) Tj 0.239024 0 Td 11.382114 Tz (. ) Tj 60 0 0 60 0 1416.032476 Tm 22.233333 0 Td 19.444444 Tz ( ) Tj 0.283333 0 Td 41.414141 Tz (Substantial ) Tj 3.083333 0 Td 35.069444 Tz (identity ) Tj 1.783333 0 Td 33.333333 Tz ( ) Tj 0.5 0 Td 47.222222 Tz (of ) Tj 0.733333 0 Td 50.555556 Tz (amino ) Tj 1.766667 0 Td 43.055556 Tz (acid ) Tj 1.266667 0 Td 45.679012 Tz (sequences ) Tj 2.716667 0 Td 39.814815 Tz (for ) Tj 0.916667 0 Td 42.777778 Tz (these ) Tj 61.292517 0 0 61.292517 0 1375.727679 Tm 5.889789 0 Td 57.103219 Tz (Two ) Tj 1.19101 0 Td 41.564928 Tz (nucleic ) Tj 1.925194 0 Td 42.147614 Tz (acid ) Tj 1.19101 0 Td 44.715748 Tz (sequences ) Tj 2.594118 0 Td 42.147614 Tz (or ) Tj 0.636293 0 Td 43.054014 Tz (polypeptides ) Tj 3.279356 0 Td 39.881613 Tz (are ) Tj 0.913651 0 Td 39.428413 Tz (said ) Tj 1.093119 0 Td 36.709212 Tz (to ) Tj 0.619978 0 Td 47.586016 Tz (be ) Tj 1.794673 0 Td 44.526915 Tz (purposes ) Tj 2.333074 0 Td 45.546615 Tz (normally ) Tj 2.365705 0 Td 51.120977 Tz (means ) Tj 1.745727 0 Td 45.886515 Tz (sequence ) Tj 2.38202 0 Td 38.408713 Tz (identity ) Tj 2.023085 0 Td 46.226415 Tz (of ) Tj 0.668923 0 Td 35.349612 Tz (at ) Tj 0.603663 0 Td 36.437292 Tz (least ) Tj 1.272586 0 Td 48.945616 Tz (40 ) Tj 0.619978 0 Td 78.856826 Tz (% ) Tj 0.538402 0 Td 10.876804 Tz (. ) Tj 60 0 0 60 0 1334.047985 Tm 5.383333 0 Td 16.666667 Tz ( ) Tj 0.15 0 Td 44.135802 Tz (identical ) Tj 2.433333 0 Td 16.666667 Tz ( ) Tj 0.416667 0 Td 34.722222 Tz (if ) Tj 0.65 0 Td 42.592593 Tz (the ) Tj 1.1 0 Td 46.527778 Tz (sequence ) Tj 2.566667 0 Td 45.833333 Tz (of ) Tj 0.8 0 Td 42.676768 Tz (nucleotides ) Tj 3.15 0 Td 43.055556 Tz (or ) Tj 0.816667 0 Td 50.555556 Tz (amino ) Tj 1.85 0 Td 43.055556 Tz (acid ) Tj 2.3 0 Td 52.777778 Tz (The ) Tj 1.083333 0 Td 43.650794 Tz (percent ) Tj 2 0 Td 39.236111 Tz (identity ) Tj 2.05 0 Td 45.833333 Tz (of ) Tj 0.633333 0 Td 43.981481 Tz (polypeptides ) Tj 3.35 0 Td 47.222222 Tz (can ) Tj 0.983333 0 Td 48.611111 Tz (be ) Tj 0.75 0 Td 48.148148 Tz (any ) Tj 1.033333 0 Td 41.269841 Tz (integer ) Tj 1.866667 0 Td 50 Tz (from ) Tj 68.571429 0 0 68.571429 0 1286.562712 Tm 4.695833 0 Td 37.065972 Tz (residues ) Tj 1.764583 0 Td 21.875 Tz (, ) Tj 0.277083 0 Td 36.255787 Tz (respectively ) Tj 2.58125 0 Td 24.305556 Tz (, ) Tj 0.277083 0 Td 34.027778 Tz (in ) Tj 0.510417 0 Td 36.458333 Tz (the ) Tj 0.7875 0 Td 43.75 Tz (two ) Tj 0.947917 0 Td 39.969136 Tz (sequences ) Tj 2.304167 0 Td 27.951389 Tz (is ) Tj 0.466667 0 Td 36.458333 Tz (the ) Tj 0.802083 0 Td 44.965278 Tz (same ) Tj 1.195833 0 Td 49.826389 Tz (when ) Tj 1.516667 0 Td 34.027778 Tz (40 ) Tj 0.7875 0 Td 31.597222 Tz (at ) Tj 0.7 0 Td 32.569444 Tz (least ) Tj 1.3125 0 Td 43.75 Tz (40 ) Tj 0.539583 0 Td 70.486111 Tz (% ) Tj 0.758333 0 Td 32.8125 Tz (to ) Tj 0.7875 0 Td 42.12963 Tz (100 ) Tj 0.772917 0 Td 70.486111 Tz (% ) Tj 0.7875 0 Td 24.305556 Tz (\( ) Tj 0.160417 0 Td 30.989583 Tz (e.g. ) Tj 0.802083 0 Td 12.152778 Tz (, ) Tj 0.4375 0 Td 30.381944 Tz (at ) Tj 0.7 0 Td 32.569444 Tz (least ) Tj 1.3125 0 Td 42.534722 Tz (40 ) Tj 0.539583 0 Td 70.486111 Tz (% ) Tj 0.466667 0 Td 12.152778 Tz (, ) Tj 0.4375 0 Td 38.888889 Tz (41 ) Tj 0.539583 0 Td 70.486111 Tz (% ) Tj 0.48125 0 Td 12.152778 Tz (, ) Tj 0.422917 0 Td 42.534722 Tz (42 ) Tj 0.554167 0 Td 70.486111 Tz (% ) Tj 0.466667 0 Td 12.152778 Tz (, ) Tj 60 0 0 60 0 1248.185342 Tm 5.383333 0 Td 43.650794 Tz (aligned ) Tj 2.066667 0 Td 40.740741 Tz (for ) Tj 0.95 0 Td 60.31746 Tz (maximum ) Tj 2.783333 0 Td 46.230159 Tz (correspondence ) Tj 4.15 0 Td 40.277778 Tz (as ) Tj 0.75 0 Td 44.135802 Tz (described ) Tj 2.616667 0 Td 50 Tz (below ) Tj 1.533333 0 Td 11.111111 Tz (. ) Tj 1.383333 0 Td 47.222222 Tz (43 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.55 0 Td 13.888889 Tz (, ) Tj 1.866667 0 Td 48.611111 Tz (70 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.366667 0 Td 44.444444 Tz (71 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.366667 0 Td 48.611111 Tz (72 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.55 0 Td 13.888889 Tz (, ) Tj 0.35 0 Td 47.222222 Tz (73 ) Tj 0.633333 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.35 0 Td 48.611111 Tz (74 ) Tj 0.633333 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.366667 0 Td 45.833333 Tz (75 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.366667 0 Td 48.611111 Tz (76 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.533333 0 Td 13.888889 Tz (, ) Tj 0.366667 0 Td 48.611111 Tz (77 ) Tj 0.616667 0 Td 80.555556 Tz (% ) Tj 0.55 0 Td 13.888889 Tz (, ) Tj 56.666667 0 0 56.666667 0 1208.220548 Tm 5.7 0 Td 55.882353 Tz (The ) Tj 1.164706 0 Td 48.235294 Tz (terms ) Tj 1.694118 0 Td 35.294118 Tz ( ) Tj 0.317647 0 Td 42.810458 Tz (identical ) Tj 2.223529 0 Td 35.294118 Tz ( ) Tj 0.441176 0 Td 45.588235 Tz (or ) Tj 0.723529 0 Td 26.470588 Tz ( ) Tj 0.3 0 Td 45.378151 Tz (percent ) Tj 2.170588 0 Td 37.5 Tz (identity ) Tj 1.923529 0 Td 35.294118 Tz (, ) Tj 0.158824 0 Td 35.294118 Tz ( ) Tj 0.441176 0 Td 41.176471 Tz (in ) Tj 0.652941 0 Td 44.117647 Tz (the ) Tj 0.988235 0 Td 45.798319 Tz (context ) Tj 2.1 0 Td 50 Tz (of ) Tj 1.888235 0 Td 51.470588 Tz (78 ) Tj 0.652941 0 Td 85.294118 Tz (% ) Tj 0.582353 0 Td 14.705882 Tz (, ) Tj 0.370588 0 Td 51.470588 Tz (79 ) Tj 0.652941 0 Td 85.294118 Tz (% ) Tj 0.582353 0 Td 14.705882 Tz (, ) Tj 0.388235 0 Td 51.470588 Tz (80 ) Tj 0.652941 0 Td 85.294118 Tz (% ) Tj 0.564706 0 Td 14.705882 Tz (, ) Tj 0.388235 0 Td 45.588235 Tz (81 ) Tj 0.652941 0 Td 85.294118 Tz (% ) Tj 0.564706 0 Td 14.705882 Tz (, ) Tj 0.388235 0 Td 50 Tz (82 ) Tj 0.652941 0 Td 85.294118 Tz (% ) Tj 0.564706 0 Td 14.705882 Tz (, ) Tj 0.405882 0 Td 47.058824 Tz (83 ) Tj 0.635294 0 Td 85.294118 Tz (% ) Tj 0.564706 0 Td 14.705882 Tz (, ) Tj 0.405882 0 Td 48.529412 Tz (84 ) Tj 0.635294 0 Td 85.294118 Tz (% ) Tj 0.564706 0 Td 14.705882 Tz (, ) Tj 0.405882 0 Td 48.529412 Tz (85 ) Tj 0.635294 0 Td 85.294118 Tz (% ) Tj 0.564706 0 Td 14.705882 Tz (, ) Tj 0.405882 0 Td 50 Tz (86 ) Tj 0.635294 0 Td 85.294118 Tz (% ) Tj 0.582353 0 Td 14.705882 Tz (, ) Tj 0.388235 0 Td 50 Tz (87 ) Tj 0.635294 0 Td 85.294118 Tz (% ) Tj 0.582353 0 Td 14.705882 Tz (, ) Tj 56.968641 0 0 56.968641 0 1165.266173 Tm 5.652232 0 Td 53.635746 Tz (two ) Tj 1.158532 0 Td 45.346585 Tz (or ) Tj 0.684587 0 Td 56.317533 Tz (more ) Tj 1.509602 0 Td 44.719674 Tz (nucleic ) Tj 2.071315 0 Td 43.298675 Tz (acids ) Tj 1.509602 0 Td 45.346585 Tz (or ) Tj 0.684587 0 Td 46.809378 Tz (polypeptide ) Tj 3.300061 0 Td 49.734964 Tz (sequences ) Tj 2.668135 0 Td 20.479103 Tz (, ) Tj 0.280856 0 Td 41.543323 Tz (refer ) Tj 1.386728 0 Td 40.958206 Tz (to ) Tj 1.878226 0 Td 49.734964 Tz (88 ) Tj 0.631927 0 Td 84.841998 Tz (% ) Tj 0.579266 0 Td 14.627931 Tz (, ) Tj 0.386177 0 Td 49.734964 Tz (89 ) Tj 0.631927 0 Td 84.841998 Tz (% ) Tj 0.579266 0 Td 14.627931 Tz (, ) Tj 0.386177 0 Td 51.197757 Tz (90 ) Tj 0.64948 0 Td 84.841998 Tz (% ) Tj 0.561713 0 Td 14.627931 Tz (, ) Tj 0.386177 0 Td 45.346585 Tz (91 ) Tj 0.64948 0 Td 84.841998 Tz (% ) Tj 0.561713 0 Td 14.627931 Tz (, ) Tj 0.386177 0 Td 49.734964 Tz (92 ) Tj 0.64948 0 Td 84.841998 Tz (% ) Tj 0.561713 0 Td 14.627931 Tz (, ) Tj 0.403731 0 Td 46.809378 Tz (93 ) Tj 0.631927 0 Td 84.841998 Tz (% ) Tj 0.561713 0 Td 14.627931 Tz (, ) Tj 0.403731 0 Td 48.272171 Tz (94 ) Tj 0.631927 0 Td 84.841998 Tz (% ) Tj 0.561713 0 Td 14.627931 Tz (, ) Tj 0.403731 0 Td 48.272171 Tz (95 ) Tj 0.631927 0 Td 84.841998 Tz (% ) Tj 0.561713 0 Td 14.627931 Tz (, ) Tj 0.403731 0 Td 49.734964 Tz (96 ) Tj 0.631927 0 Td 84.841998 Tz (% ) Tj 0.579266 0 Td 14.627931 Tz (, ) Tj 0.386177 0 Td 49.734964 Tz (97 ) Tj 0.631927 0 Td 84.841998 Tz (% ) Tj 0.579266 0 Td 14.627931 Tz (, ) Tj 59.458128 0 0 59.458128 0 1124.491741 Tm 5.415576 0 Td 51.39004 Tz (two ) Tj 1.110025 0 Td 43.447943 Tz (or ) Tj 0.672742 0 Td 53.258768 Tz (more ) Tj 1.480033 0 Td 46.095308 Tz (sequences ) Tj 2.690969 0 Td 42.046396 Tz (or ) Tj 0.689561 0 Td 46.718218 Tz (subsequences ) Tj 3.548716 0 Td 39.243303 Tz (that ) Tj 1.110025 0 Td 41.112032 Tz (are ) Tj 0.908202 0 Td 42.046396 Tz (the ) Tj 0.958658 0 Td 51.857222 Tz (same ) Tj 1.429577 0 Td 43.447943 Tz (or ) Tj 1.816404 0 Td 47.652582 Tz (98 ) Tj 0.605468 0 Td 81.289699 Tz (% ) Tj 0.555012 0 Td 14.015465 Tz (, ) Tj 0.285915 0 Td 46.251036 Tz (99 ) Tj 0.605468 0 Td 81.289699 Tz (% ) Tj 0.538194 0 Td 14.015465 Tz (, ) Tj 0.319553 0 Td 48.586947 Tz (100 ) Tj 0.908202 0 Td 81.289699 Tz (% ) Tj 0.521375 0 Td 28.030931 Tz (\) ) Tj 0.23546 0 Td 11.212372 Tz (. ) Tj 0.269097 0 Td 58.164181 Tz (Some ) Tj 1.547307 0 Td 50.965329 Tz (embodiments ) Tj 3.531897 0 Td 43.648163 Tz (include ) Tj 1.98459 0 Td 36.44021 Tz (at ) Tj 0.58865 0 Td 37.561447 Tz (least ) Tj 1.295029 0 Td 49.054129 Tz (60 ) Tj 0.622287 0 Td 81.289699 Tz (% ) Tj 0.538194 0 Td 14.015465 Tz (, ) Tj 61.428571 0 0 61.428571 0 1082.532821 Tm 5.24186 0 Td 47.48062 Tz (have ) Tj 1.530233 0 Td 40.697674 Tz (a ) Tj 0.634884 0 Td 39.491817 Tz (specified ) Tj 2.490698 0 Td 43.682171 Tz (percentage ) Tj 3.011628 0 Td 46.124031 Tz (of ) Tj 0.862791 0 Td 49.379845 Tz (amino ) Tj 1.872093 0 Td 42.054264 Tz (acid ) Tj 1.367442 0 Td 41.036822 Tz (residues ) Tj 2.360465 0 Td 42.054264 Tz (or ) Tj 0.862791 0 Td 36.627907 Tz (45 ) Tj 0.895349 0 Td 44.767442 Tz (65 ) Tj 0.586047 0 Td 78.682171 Tz (% ) Tj 0.537209 0 Td 13.565891 Tz (, ) Tj 0.35814 0 Td 48.837209 Tz (70 ) Tj 0.618605 0 Td 78.682171 Tz (% ) Tj 0.52093 0 Td 13.565891 Tz (, ) Tj 0.374419 0 Td 46.124031 Tz (75 ) Tj 0.602326 0 Td 78.682171 Tz (% ) Tj 0.537209 0 Td 13.565891 Tz (, ) Tj 0.390698 0 Td 46.124031 Tz (80 ) Tj 0.586047 0 Td 78.682171 Tz (% ) Tj 0.52093 0 Td 13.565891 Tz (, ) Tj 0.390698 0 Td 44.767442 Tz (85 ) Tj 0.602326 0 Td 78.682171 Tz (% ) Tj 0.52093 0 Td 13.565891 Tz (, ) Tj 0.390698 0 Td 46.124031 Tz (90 ) Tj 0.586047 0 Td 78.682171 Tz (% ) Tj 0.52093 0 Td 13.565891 Tz (, ) Tj 0.390698 0 Td 44.767442 Tz (95 ) Tj 0.602326 0 Td 78.682171 Tz (% ) Tj 0.52093 0 Td 13.565891 Tz (, ) Tj 0.374419 0 Td 42.054264 Tz (or ) Tj 0.765116 0 Td 44.767442 Tz (99 ) Tj 0.586047 0 Td 78.682171 Tz (% ) Tj 0.748837 0 Td 37.645349 Tz (identity ) Tj 1.75814 0 Td 27.131783 Tz (. ) Tj 59.699248 0 0 59.699248 0 1043.006971 Tm 5.393703 0 Td 42.891764 Tz (nucleotides ) Tj 3.065365 0 Td 39.084803 Tz (that ) Tj 1.172544 0 Td 40.945984 Tz (are ) Tj 0.954786 0 Td 41.876574 Tz (the ) Tj 1.021788 0 Td 51.647775 Tz (same ) Tj 1.289798 0 Td 13.958858 Tz (, ) Tj 0.335013 0 Td 56.533375 Tz (when ) Tj 1.574559 0 Td 51.298804 Tz (compared ) Tj 2.680101 0 Td 50.251889 Tz (and ) Tj 1.122292 0 Td 43.870697 Tz (aligned ) Tj 3.115617 0 Td 53.043661 Tz (The ) Tj 1.155793 0 Td 43.073048 Tz (present ) Tj 2.043577 0 Td 43.427559 Tz (invention ) Tj 2.546096 0 Td 44.668346 Tz (provides ) Tj 2.378589 0 Td 40.945984 Tz (for ) Tj 0.921285 0 Td 44.203051 Tz (polypeptides ) Tj 3.417128 0 Td 39.084803 Tz (that ) Tj 1.155793 0 Td 40.945984 Tz (are ) Tj 0.971537 0 Td 36.293031 Tz (at ) Tj 65.324675 0 0 65.324675 0 998.221777 Tm 4.944533 0 Td 36.569472 Tz (for ) Tj 0.872565 0 Td 55.036448 Tz (maximum ) Tj 2.541153 0 Td 42.461895 Tz (correspondence ) Tj 3.81173 0 Td 42.097416 Tz (over ) Tj 1.224652 0 Td 38.270378 Tz (a ) Tj 0.459245 0 Td 44.393638 Tz (comparison ) Tj 2.877932 0 Td 50.601944 Tz (window ) Tj 1.836978 0 Td 12.756793 Tz (, ) Tj 1.285885 0 Td 34.188204 Tz (least ) Tj 1.255268 0 Td 36.504053 Tz (substantially ) Tj 3.076938 0 Td 35.719019 Tz (identical ) Tj 2.143141 0 Td 34.44334 Tz (to ) Tj 0.65825 0 Td 57.830793 Tz (SEQ ) Tj 1.270577 0 Td 47.200133 Tz (ID ) Tj 0.780716 0 Td 57.405567 Tz (NOS3 ) Tj 1.454274 0 Td 12.756793 Tz (, ) Tj 0.321471 0 Td 40.821736 Tz (7 ) Tj 0.306163 0 Td 12.756793 Tz (, ) Tj 0.321471 0 Td 38.270378 Tz (8 ) Tj 0.474553 0 Td 38.270378 Tz (or ) Tj 0.673559 0 Td 38.270378 Tz (9 ) Tj 0.306163 0 Td 10.205434 Tz (. ) Tj 65.714286 0 0 65.714286 0 958.686003 Tm 4.915217 0 Td 36.775362 Tz (as ) Tj 0.63913 0 Td 45.652174 Tz (measured ) Tj 2.358696 0 Td 41.086957 Tz (using ) Tj 1.430435 0 Td 43.961353 Tz (one ) Tj 1.004348 0 Td 41.847826 Tz (of ) Tj 0.63913 0 Td 38.043478 Tz (the ) Tj 0.882609 0 Td 40.57971 Tz (following ) Tj 2.404348 0 Td 42.798913 Tz (sequence ) Tj 2.358696 0 Td 47.101449 Tz (compari ) Tj 55.873016 0 0 55.873016 0 960.271505 Tm 23.85767 0 Td 61.448864 Tz (Amino ) Tj 2.12983 0 Td 45.490057 Tz (acid ) Tj 1.360227 0 Td 43.004261 Tz (substitution ) Tj 3.328977 0 Td 46.608665 Tz (matrices ) Tj 2.52358 0 Td 53.693182 Tz (and ) Tj 1.199148 0 Td 41.164773 Tz (their ) Tj 1.449716 0 Td 49.715909 Tz (use ) Tj 1.163352 0 Td 41.761364 Tz (in ) Tj 0.823295 0 Td 60.40483 Tz (quan ) Tj 60.827068 0 0 60.827068 0 918.638178 Tm 5.326576 0 Td 45.666804 Tz (son ) Tj 1.052163 0 Td 43.29213 Tz (algorithms ) Tj 2.860569 0 Td 41.100124 Tz (or ) Tj 0.706922 0 Td 50.690152 Tz (by ) Tj 0.838443 0 Td 49.776816 Tz (manual ) Tj 2.038566 0 Td 45.362359 Tz (alignment ) Tj 2.679728 0 Td 49.320148 Tz (and ) Tj 1.101483 0 Td 40.186788 Tz (visual ) Tj 1.808405 0 Td 39.142975 Tz (inspec- ) Tj 2.893449 0 Td 38.751545 Tz (tifying ) Tj 1.759085 0 Td 41.100124 Tz (the ) Tj 0.904203 0 Td 38.634116 Tz (similarity ) Tj 2.449567 0 Td 48.928719 Tz (between ) Tj 2.170087 0 Td 50.233484 Tz (two ) Tj 1.085043 0 Td 45.057913 Tz (sequences ) Tj 2.597528 0 Td 40.186788 Tz (are ) Tj 0.854883 0 Td 44.525134 Tz (well ) Tj 1.167244 0 Td 19.180058 Tz (- ) Tj 0.14796 0 Td 54.252163 Tz (known ) Tj 64.285714 0 0 64.285714 0 876.383571 Tm 5.008889 0 Td 38.240741 Tz (tion ) Tj 0.948889 0 Td 10.37037 Tz (. ) Tj 0.451111 0 Td 57.037037 Tz (When ) Tj 1.711111 0 Td 41.740741 Tz (percentage ) Tj 2.877778 0 Td 44.074074 Tz (of ) Tj 0.84 0 Td 43.425926 Tz (sequence ) Tj 2.457778 0 Td 36.296296 Tz (identity ) Tj 2.115556 0 Td 28.518519 Tz (is ) Tj 0.715556 0 Td 44.722222 Tz (used ) Tj 1.415556 0 Td 37.592593 Tz (in ) Tj 0.808889 0 Td 35 Tz (50 ) Tj 0.824444 0 Td 36.296296 Tz (in ) Tj 0.575556 0 Td 38.888889 Tz (the ) Tj 0.871111 0 Td 35.432099 Tz (art ) Tj 0.668889 0 Td 15.555556 Tz (. ) Tj 0.186667 0 Td 70 Tz (A ) Tj 0.528889 0 Td 43.425926 Tz (high ) Tj 1.213333 0 Td 36.555556 Tz (similarity ) Tj 2.348889 0 Td 39.753086 Tz (generally ) Tj 2.317778 0 Td 37.074074 Tz (correlates ) Tj 2.38 0 Td 43.425926 Tz (with ) Tj 1.244444 0 Td 53.925926 Tz (homol ) Tj 60.064935 0 0 60.064935 0 835.023676 Tm 5.360865 0 Td 42.854855 Tz (reference ) Tj 2.447351 0 Td 37.459459 Tz (to ) Tj 0.616 0 Td 41.274775 Tz (proteins ) Tj 2.147676 0 Td 43.009009 Tz (or ) Tj 0.632649 0 Td 42.662162 Tz (peptides ) Tj 2.114378 0 Td 13.873874 Tz (, ) Tj 0.266378 0 Td 27.747748 Tz (it ) Tj 0.482811 0 Td 30.522523 Tz (is ) Tj 0.516108 0 Td 45.783784 Tz (recognized ) Tj 2.863568 0 Td 38.846847 Tz (that ) Tj 1.065514 0 Td 42.810811 Tz (residue ) Tj 3.063351 0 Td 49.021021 Tz (ogy ) Tj 1.098811 0 Td 45.783784 Tz (of ) Tj 0.649297 0 Td 41.621622 Tz (the ) Tj 0.948973 0 Td 45.62963 Tz (sequences ) Tj 2.547243 0 Td 11.099099 Tz (. ) Tj 0.266378 0 Td 52.720721 Tz (The ) Tj 1.132108 0 Td 65.900901 Tz (BLOSUM62 ) Tj 3.363027 0 Td 44.858859 Tz (matrix ) Tj 1.798054 0 Td 30.522523 Tz (is ) Tj 0.566054 0 Td 41.621622 Tz (often ) Tj 1.431784 0 Td 45.783784 Tz (used ) Tj 63.492063 0 0 63.492063 0 790.548077 Tm 5.0715 0 Td 39.083333 Tz (positions ) Tj 2.331 0 Td 36.75 Tz (that ) Tj 1.1025 0 Td 38.5 Tz (are ) Tj 0.89775 0 Td 41.125 Tz (not ) Tj 0.96075 0 Td 37.625 Tz (identical ) Tj 2.2365 0 Td 39.9 Tz (often ) Tj 1.40175 0 Td 35 Tz (differ ) Tj 1.449 0 Td 48.5625 Tz (by ) Tj 0.80325 0 Td 41.125 Tz (conservative ) Tj 4.17375 0 Td 38.0625 Tz (as ) Tj 0.70875 0 Td 39.375 Tz (a ) Tj 0.4725 0 Td 38.625 Tz (default ) Tj 1.87425 0 Td 40.5 Tz (scoring ) Tj 1.953 0 Td 37.84375 Tz (substitution ) Tj 2.961 0 Td 41.5625 Tz (matrix ) Tj 1.74825 0 Td 36.75 Tz (in ) Tj 0.693 0 Td 43.96875 Tz (sequence ) Tj 2.4255 0 Td 44.1 Tz (align ) Tj 57.428571 0 0 57.428571 0 750.791395 Tm 5.624378 0 Td 52.819237 Tz (amino ) Tj 1.915423 0 Td 44.257877 Tz (acid ) Tj 1.375622 0 Td 41.969639 Tz (substitutions ) Tj 3.256219 0 Td 26.119403 Tz (, ) Tj 0.452736 0 Td 52.819237 Tz (where ) Tj 1.89801 0 Td 52.819237 Tz (amino ) Tj 1.915423 0 Td 42.951907 Tz (acids ) Tj 1.60199 0 Td 43.895108 Tz (residues ) Tj 2.437811 0 Td 42.564953 Tz (are ) Tj 2.089552 0 Td 53.689884 Tz (ment ) Tj 1.514925 0 Td 44.499724 Tz (protocols ) Tj 2.664179 0 Td 48.611111 Tz (such ) Tj 1.393035 0 Td 42.08126 Tz (as ) Tj 0.766169 0 Td 55.624655 Tz (Gapped ) Tj 2.228856 0 Td 67.910448 Tz (BLAST ) Tj 2.263682 0 Td 43.532338 Tz (2.0 ) Tj 0.853234 0 Td 11.608624 Tz (. ) Tj 0.330846 0 Td 54.173577 Tz (The ) Tj 1.218905 0 Td 49.33665 Tz (gap ) Tj 1.218905 0 Td 49.33665 Tz (exis ) Tj 55.5 0 0 55.5 0 712.135241 Tm 5.837838 0 Td 43.953044 Tz (substituted ) Tj 3.045045 0 Td 43.043043 Tz (for ) Tj 0.936937 0 Td 45.645646 Tz (other ) Tj 1.513514 0 Td 54.654655 Tz (amino ) Tj 1.837838 0 Td 45.795796 Tz (acid ) Tj 1.243243 0 Td 45.42042 Tz (residues ) Tj 2.342342 0 Td 50.3003 Tz (with ) Tj 1.387387 0 Td 43.758044 Tz (similar ) Tj 2 0 Td 52.052052 Tz (chemi- ) Tj 3.207207 0 Td 46.846847 Tz (tence ) Tj 1.747748 0 Td 46.761047 Tz (penalty ) Tj 2.324324 0 Td 33.033033 Tz (is ) Tj 0.774775 0 Td 54.054054 Tz (imposed ) Tj 2.594595 0 Td 44.044044 Tz (for ) Tj 1.117117 0 Td 51.051051 Tz (opening ) Tj 2.486486 0 Td 52.052052 Tz (gap ) Tj 1.297297 0 Td 43.543544 Tz (in ) Tj 0.846847 0 Td 53.053053 Tz (one ) Tj 1.297297 0 Td 51.051051 Tz (of ) Tj 0.864865 0 Td 46.046046 Tz (the ) Tj 60 0 0 60 0 669.828987 Tm 5.383333 0 Td 37.962963 Tz (cal ) Tj 0.883333 0 Td 41.111111 Tz (properties ) Tj 2.683333 0 Td 27.777778 Tz (\( ) Tj 0.183333 0 Td 35.416667 Tz (e.g. ) Tj 0.916667 0 Td 13.888889 Tz (, ) Tj 0.316667 0 Td 44.907407 Tz (charge ) Tj 1.816667 0 Td 41.666667 Tz (or ) Tj 0.65 0 Td 44.642857 Tz (hydrophobicity ) Tj 3.833333 0 Td 27.777778 Tz (\) ) Tj 0.366667 0 Td 50 Tz (and ) Tj 1.05 0 Td 41.666667 Tz (therefore ) Tj 2.65 0 Td 36.111111 Tz (55 ) Tj 0.883333 0 Td 43.253968 Tz (aligned ) Tj 2 0 Td 46.604938 Tz (sequences ) Tj 2.5 0 Td 19.444444 Tz (, ) Tj 0.3 0 Td 49.074074 Tz (and ) Tj 1.033333 0 Td 41.666667 Tz (the ) Tj 0.916667 0 Td 47.222222 Tz (gap ) Tj 1.033333 0 Td 44.135802 Tz (extension ) Tj 2.516667 0 Td 43.650794 Tz (penalty ) Tj 2 0 Td 30.555556 Tz (is ) Tj 0.55 0 Td 50 Tz (imposed ) Tj 60.595238 0 0 60.595238 0 625.54491 Tm 5.330452 0 Td 48.133595 Tz (do ) Tj 0.891159 0 Td 43.091028 Tz (not ) Tj 1.072692 0 Td 48.133595 Tz (change ) Tj 2.01336 0 Td 42.174198 Tz (the ) Tj 1.056189 0 Td 41.257367 Tz (functional ) Tj 2.772495 0 Td 40.707269 Tz (properties ) Tj 2.772495 0 Td 45.383104 Tz (of ) Tj 0.775639 0 Td 41.257367 Tz (the ) Tj 1.039686 0 Td 46.75835 Tz (molecule ) Tj 2.310413 0 Td 11.001965 Tz (. ) Tj 1.369745 0 Td 39.423707 Tz (for ) Tj 0.907662 0 Td 46.070727 Tz (each ) Tj 1.303733 0 Td 50.058939 Tz (amino ) Tj 1.732809 0 Td 41.94499 Tz (acid ) Tj 1.188212 0 Td 41.601179 Tz (position ) Tj 2.194892 0 Td 38.506876 Tz (in ) Tj 0.643615 0 Td 41.257367 Tz (the ) Tj 0.957171 0 Td 46.75835 Tz (gap ) Tj 0.924165 0 Td 11.001965 Tz (. ) Tj 0.28055 0 Td 50.884086 Tz (Thus ) Tj 1.188212 0 Td 24.75442 Tz (, ) Tj 0.396071 0 Td 41.257367 Tz (a ) Tj 0.429077 0 Td 50.425671 Tz (two ) Tj 1.138703 0 Td 49.508841 Tz (amino ) Tj 61.632653 0 0 61.632653 0 581.835302 Tm 5.240728 0 Td 53.002208 Tz (Where ) Tj 1.91457 0 Td 44.468972 Tz (sequences ) Tj 2.725828 0 Td 36.055923 Tz (differ ) Tj 1.590066 0 Td 37.85872 Tz (in ) Tj 0.746358 0 Td 42.36571 Tz (conservative ) Tj 3.374834 0 Td 39.314824 Tz (substitutions ) Tj 3.034106 0 Td 24.337748 Tz (, ) Tj 0.438079 0 Td 40.562914 Tz (the ) Tj 1.97947 0 Td 41.915011 Tz (acid ) Tj 1.314238 0 Td 41.721854 Tz (residue ) Tj 2.093046 0 Td 45.971302 Tz (gap ) Tj 1.184437 0 Td 38.534768 Tz (will ) Tj 1.265563 0 Td 37.408021 Tz (result ) Tj 1.687417 0 Td 39.210817 Tz (in ) Tj 0.795033 0 Td 40.562914 Tz (a ) Tj 0.584106 0 Td 42.108168 Tz (penalty ) Tj 2.125497 0 Td 45.971302 Tz (of ) Tj 0.876159 0 Td 41.915011 Tz (13 ) Tj 0.567881 0 Td 13.520971 Tz (, ) Tj 0.519205 0 Td 36.506623 Tz (11 ) Tj 0.859934 0 Td 38.760118 Tz (for ) Tj 61.571429 0 0 61.571429 0 544.771181 Tm 5.213457 0 Td 42.536736 Tz (percent ) Tj 2.192575 0 Td 45.340294 Tz (sequence ) Tj 2.566125 0 Td 38.234725 Tz (identity ) Tj 2.208817 0 Td 56.844548 Tz (may ) Tj 1.396752 0 Td 47.370456 Tz (be ) Tj 0.958237 0 Td 41.95669 Tz (adjusted ) Tj 2.37123 0 Td 48.3372 Tz (upwards ) Tj 2.419954 0 Td 37.896365 Tz (to ) Tj 1.737819 0 Td 41.505543 Tz (existence ) Tj 2.436195 0 Td 44.663573 Tz (of ) Tj 0.649652 0 Td 40.603248 Tz (the ) Tj 0.925754 0 Td 46.919309 Tz (gap ) Tj 1.055684 0 Td 47.821604 Tz (and ) Tj 1.039443 0 Td 43.310131 Tz (2 ) Tj 0.470998 0 Td 39.700954 Tz (for ) Tj 0.87703 0 Td 43.911661 Tz (extending ) Tj 2.549884 0 Td 40.603248 Tz (the ) Tj 0.941995 0 Td 46.017015 Tz (gap ) Tj 1.023202 0 Td 48.723898 Tz (two ) Tj 1.104408 0 Td 48.723898 Tz (amino ) Tj 56.666667 0 0 56.666667 0 503.36924 Tm 5.7 0 Td 43.277311 Tz (correct ) Tj 1.976471 0 Td 42.156863 Tz (for ) Tj 0.882353 0 Td 44.117647 Tz (the ) Tj 0.952941 0 Td 46.078431 Tz (conservative ) Tj 3.458824 0 Td 45.588235 Tz (nature ) Tj 1.817647 0 Td 48.529412 Tz (of ) Tj 0.652941 0 Td 45.098039 Tz (the ) Tj 0.988235 0 Td 41.176471 Tz (substitution ) Tj 3.052941 0 Td 20.588235 Tz (. ) Tj 0.317647 0 Td 57.058824 Tz (Means ) Tj 3.088235 0 Td 43.529412 Tz (acids ) Tj 1.394118 0 Td 11.764706 Tz (. ) Tj 0.3 0 Td 55.882353 Tz (The ) Tj 1.217647 0 Td 48.366013 Tz (alignment ) Tj 2.823529 0 Td 33.823529 Tz (is ) Tj 0.635294 0 Td 45.798319 Tz (defined ) Tj 2.117647 0 Td 52.941176 Tz (by ) Tj 0.847059 0 Td 44.117647 Tz (the ) Tj 1.005882 0 Td 53.529412 Tz (amino ) Tj 1.835294 0 Td 45.588235 Tz (acid ) Tj 1.270588 0 Td 43.79085 Tz (positions ) Tj 57.142857 0 0 57.142857 0 461.304569 Tm 5.6525 0 Td 41.805556 Tz (for ) Tj 0.945 0 Td 53.958333 Tz (making ) Tj 2.1525 0 Td 37.916667 Tz (this ) Tj 1.155 0 Td 47.25 Tz (adjustment ) Tj 3.0625 0 Td 42.777778 Tz (are ) Tj 0.9625 0 Td 45.9375 Tz (well ) Tj 1.3125 0 Td 60.083333 Tz (known ) Tj 1.9775 0 Td 39.375 Tz (to ) Tj 0.7 0 Td 45.5 Tz (those ) Tj 1.5925 0 Td 49.583333 Tz (of ) Tj 0.7525 0 Td 35.583333 Tz (skill ) Tj 1.5225 0 Td 37.916667 Tz (60 ) Tj 0.91 0 Td 49.583333 Tz (of ) Tj 0.77 0 Td 49.583333 Tz (each ) Tj 1.4525 0 Td 48.854167 Tz (sequence ) Tj 2.6075 0 Td 37.916667 Tz (at ) Tj 0.6825 0 Td 53.666667 Tz (which ) Tj 1.8375 0 Td 43.75 Tz (the ) Tj 1.05 0 Td 47.962963 Tz (alignment ) Tj 2.8175 0 Td 46.666667 Tz (begins ) Tj 1.96 0 Td 51.527778 Tz (and ) Tj 1.1725 0 Td 48.854167 Tz (ends ) Tj 1.19 0 Td 26.25 Tz (, ) Tj 64.285714 0 0 64.285714 0 417.009265 Tm 5.024444 0 Td 36.296296 Tz (in ) Tj 0.7 0 Td 39.753086 Tz (the ) Tj 0.995556 0 Td 36.296296 Tz (art ) Tj 0.622222 0 Td 15.555556 Tz (. ) Tj 0.404444 0 Td 40.041152 Tz (Typically ) Tj 2.442222 0 Td 33.703704 Tz (this ) Tj 1.12 0 Td 40.185185 Tz (involves ) Tj 2.255556 0 Td 39.62963 Tz (scoring ) Tj 1.96 0 Td 38.888889 Tz (a ) Tj 0.528889 0 Td 40.617284 Tz (conservative ) Tj 4.122222 0 Td 45.802469 Tz (and ) Tj 1.011111 0 Td 38.888889 Tz (optionally ) Tj 2.52 0 Td 47.962963 Tz (by ) Tj 0.762222 0 Td 38.888889 Tz (the ) Tj 0.902222 0 Td 37.44856 Tz (insertion ) Tj 2.208889 0 Td 42.777778 Tz (of ) Tj 0.653333 0 Td 38.888889 Tz (a ) Tj 0.435556 0 Td 44.074074 Tz (gap ) Tj 1.011111 0 Td 40.185185 Tz (or ) Tj 0.637778 0 Td 40.509259 Tz (multiple ) Tj 2.131111 0 Td 42.777778 Tz (gaps ) Tj 1.244444 0 Td 36.296296 Tz (in ) Tj 61.547619 0 0 61.547619 0 375.853223 Tm 5.264217 0 Td 39.039329 Tz (substitution ) Tj 2.989555 0 Td 39.26499 Tz (as ) Tj 0.682398 0 Td 40.618956 Tz (a ) Tj 0.422437 0 Td 36.363636 Tz (partial ) Tj 1.705996 0 Td 39.716312 Tz (rather ) Tj 1.592263 0 Td 44.003868 Tz (than ) Tj 1.234816 0 Td 40.618956 Tz (a ) Tj 0.438685 0 Td 33.172147 Tz (full ) Tj 0.991103 0 Td 49.419729 Tz (mismatch ) Tj 2.404642 0 Td 13.539652 Tz (, ) Tj 0.276209 0 Td 43.326886 Tz (thereby ) Tj 3.070793 0 Td 46.93746 Tz (one ) Tj 1.023598 0 Td 41.972921 Tz (or ) Tj 0.649903 0 Td 44.680851 Tz (both ) Tj 1.251064 0 Td 44.229529 Tz (sequences ) Tj 2.48588 0 Td 18.955513 Tz (, ) Tj 0.276209 0 Td 40.618956 Tz (so ) Tj 0.682398 0 Td 39.26499 Tz (as ) Tj 0.633656 0 Td 37.911025 Tz (to ) Tj 0.649903 0 Td 38.362347 Tz (arrive ) Tj 1.559768 0 Td 35.203095 Tz (at ) Tj 0.568665 0 Td 40.618956 Tz (the ) Tj 0.893617 0 Td 41.779497 Tz (highest ) Tj 1.900967 0 Td 41.295938 Tz (possible ) Tj 61.954887 0 0 61.954887 0 335.875412 Tm 5.213471 0 Td 40.889968 Tz (increasing ) Tj 2.873058 0 Td 40.351942 Tz (the ) Tj 1.145995 0 Td 43.311084 Tz (percentage ) Tj 3.050607 0 Td 45.395934 Tz (sequence ) Tj 2.614806 0 Td 36.316748 Tz (identity ) Tj 1.727063 0 Td 26.901294 Tz (. ) Tj 0.61335 0 Td 50.439927 Tz (Thus ) Tj 1.178277 0 Td 24.211165 Tz (, ) Tj 0.597209 0 Td 38.558522 Tz (for ) Tj 1.936893 0 Td 39.27589 Tz (score ) Tj 1.275121 0 Td 13.450647 Tz (. ) Tj 0.306675 0 Td 48.42233 Tz (While ) Tj 1.6625 0 Td 43.042071 Tz (optimal ) Tj 2.033738 0 Td 44.536588 Tz (alignment ) Tj 2.614806 0 Td 47.52562 Tz (and ) Tj 1.081432 0 Td 41.12055 Tz (scoring ) Tj 1.936893 0 Td 46.62891 Tz (can ) Tj 1.016869 0 Td 47.077265 Tz (be ) Tj 0.855461 0 Td 55.416667 Tz (accom ) Tj 60.714286 0 0 60.714286 0 293.398046 Tm 5.32 0 Td 49.803922 Tz (example ) Tj 2.025882 0 Td 27.45098 Tz (, ) Tj 0.395294 0 Td 49.960784 Tz (where ) Tj 1.712941 0 Td 46.666667 Tz (an ) Tj 0.774118 0 Td 38.431373 Tz (identical ) Tj 2.305882 0 Td 49.960784 Tz (amino ) Tj 1.729412 0 Td 42.54902 Tz (acid ) Tj 1.218824 0 Td 31.568627 Tz (is ) Tj 0.609412 0 Td 45.019608 Tz (given ) Tj 1.548235 0 Td 41.176471 Tz (a ) Tj 0.494118 0 Td 41.72549 Tz (score ) Tj 1.465882 0 Td 46.666667 Tz (of ) Tj 1.745882 0 Td 42.352941 Tz (plished ) Tj 1.992941 0 Td 47.009804 Tz (manually ) Tj 2.207059 0 Td 27.45098 Tz (, ) Tj 0.411765 0 Td 41.176471 Tz (the ) Tj 0.971765 0 Td 43.529412 Tz (process ) Tj 2.075294 0 Td 31.568627 Tz (is ) Tj 0.625882 0 Td 37.183601 Tz (facilitated ) Tj 2.668235 0 Td 50.784314 Tz (by ) Tj 0.84 0 Td 41.176471 Tz (the ) Tj 0.955294 0 Td 45.751634 Tz (use ) Tj 1.054118 0 Td 46.666667 Tz (of ) Tj 0.741176 0 Td 41.176471 Tz (a ) Tj 67.142857 0 0 67.142857 0 252.510996 Tm 4.855319 0 Td 24.822695 Tz (1 ) Tj 0.476596 0 Td 43.853428 Tz (and ) Tj 1.02766 0 Td 37.234043 Tz (a ) Tj 0.476596 0 Td 44.680851 Tz (non ) Tj 0.923404 0 Td 17.375887 Tz (- ) Tj 0.178723 0 Td 37.85461 Tz (conservative ) Tj 2.993617 0 Td 35.786052 Tz (substitution ) Tj 2.814894 0 Td 28.546099 Tz (is ) Tj 0.610638 0 Td 41.205674 Tz (given ) Tj 1.474468 0 Td 37.234043 Tz (a ) Tj 0.491489 0 Td 38.22695 Tz (score ) Tj 1.4 0 Td 42.198582 Tz (of ) Tj 0.819149 0 Td 31.028369 Tz (65 ) Tj 0.774468 0 Td 43.75 Tz (computer ) Tj 2.144681 0 Td 24.822695 Tz (- ) Tj 0.223404 0 Td 42.649903 Tz (implemented ) Tj 3.097872 0 Td 40.819543 Tz (alignment ) Tj 2.502128 0 Td 36.682427 Tz (algorithm ) Tj 2.129787 0 Td 24.822695 Tz (, ) Tj 0.446809 0 Td 31.648936 Tz (e.g. ) Tj 0.819149 0 Td 12.411348 Tz (, ) Tj 0.402128 0 Td 44.267139 Tz (gapped ) Tj 59.022556 0 0 59.022556 0 211.02947 Tm 5.472484 0 Td 43.768577 Tz (zero ) Tj 1.118217 0 Td 16.942675 Tz (, ) Tj 0.372739 0 Td 42.356688 Tz (a ) Tj 0.525223 0 Td 44.239207 Tz (conservative ) Tj 3.473248 0 Td 40.709483 Tz (substitution ) Tj 3.185223 0 Td 32.473461 Tz (is ) Tj 0.677707 0 Td 46.309979 Tz (given ) Tj 1.643439 0 Td 42.356688 Tz (a ) Tj 0.542166 0 Td 43.4862 Tz (score ) Tj 1.558726 0 Td 50.424628 Tz (between ) Tj 3.405478 0 Td 66.076433 Tz (BLAST ) Tj 2.270318 0 Td 42.356688 Tz (2.0 ) Tj 0.830191 0 Td 11.295117 Tz (. ) Tj 0.406624 0 Td 50.828025 Tz (To ) Tj 0.931847 0 Td 44.12155 Tz (generate ) Tj 2.439745 0 Td 43.415605 Tz (accurate ) Tj 2.40586 0 Td 39.815287 Tz (similarity ) Tj 2.710828 0 Td 42.356688 Tz (scores ) Tj 1.829809 0 Td 45.180467 Tz (using ) Tj 59.73545 0 0 59.73545 0 168.982895 Tm 5.407174 0 Td 43.246236 Tz (zero ) Tj 1.272276 0 Td 49.291408 Tz (and ) Tj 1.138353 0 Td 30.690877 Tz (1. ) Tj 0.602657 0 Td 52.081488 Tz (The ) Tj 1.138353 0 Td 47.431355 Tz (term ) Tj 1.355979 0 Td 27.900797 Tz ( ) Tj 0.284588 0 Td 42.897476 Tz (absolute ) Tj 2.243224 0 Td 43.84411 Tz (percent ) Tj 2.059079 0 Td 38.712356 Tz (identity ) Tj 1.975376 0 Td 30.690877 Tz ( ) Tj 0.385031 0 Td 39.061116 Tz (refers ) Tj 1.607086 0 Td 39.061116 Tz (to ) Tj 0.7031 0 Td 41.851196 Tz (a ) Tj 1.523384 0 Td 61.381754 Tz (NCBI ) Tj 1.707529 0 Td 65.845881 Tz (BLAST ) Tj 1.908415 0 Td 25.110717 Tz (, ) Tj 0.385031 0 Td 26.505757 Tz (it ) Tj 0.535695 0 Td 32.085917 Tz (is ) Tj 0.619398 0 Td 44.641275 Tz (important ) Tj 2.611515 0 Td 37.666076 Tz (to ) Tj 0.68636 0 Td 41.851196 Tz (turn ) Tj 1.222055 0 Td 39.991143 Tz (off ) Tj 0.887245 0 Td 48.361382 Tz (any ) Tj 1.088131 0 Td 36.891054 Tz (filtering ) Tj 1.925155 0 Td 27.900797 Tz (, ) Tj 0.418512 0 Td 34.875996 Tz (e.g. ) Tj 0.920726 0 Td 13.950399 Tz (, ) Tj ET Q endstream endobj 181 0 obj << /Length 1 >> stream q endstream endobj 182 0 obj << /Length 56140 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.563889 0 Td 71.296296 Tz (13 ) Tj 54.285714 0 0 54.285714 0 2971 Tm 31.739474 0 Td 67.54386 Tz (14 ) Tj 60 0 0 60 0 2914.58328 Tm 5.383333 0 Td 50 Tz (low ) Tj 1.15 0 Td 46.388889 Tz (complexity ) Tj 3.016667 0 Td 36.419753 Tz (filtering ) Tj 1.95 0 Td 27.777778 Tz (, ) Tj 0.4 0 Td 49.074074 Tz (and ) Tj 1.1 0 Td 37.5 Tz (to ) Tj 0.716667 0 Td 41.269841 Tz (disable ) Tj 1.966667 0 Td 41.666667 Tz (the ) Tj 0.966667 0 Td 46.296296 Tz (use ) Tj 1.066667 0 Td 47.222222 Tz (of ) Tj 0.816667 0 Td 49.537037 Tz (compo- ) Tj 3.083333 0 Td 50.347222 Tz (Examples ) Tj 2.65 0 Td 47.222222 Tz (of ) Tj 0.716667 0 Td 41.666667 Tz (a ) Tj 0.45 0 Td 41.666667 Tz (useful ) Tj 1.75 0 Td 43.611111 Tz (algorithms ) Tj 2.85 0 Td 40.277778 Tz (in ) Tj 0.666667 0 Td 36.805556 Tz (this ) Tj 1.1 0 Td 44.444444 Tz (regard ) Tj 1.8 0 Td 43.650794 Tz (include ) Tj 1.783333 0 Td 25 Tz (, ) Tj 0.383333 0 Td 44.444444 Tz (but ) Tj 55.789474 0 0 55.789474 0 2871 Tm 5.807547 0 Td 40.828092 Tz (sition ) Tj 1.792453 0 Td 51.383648 Tz (based ) Tj 1.9 0 Td 37.641509 Tz (statistics ) Tj 2.330189 0 Td 11.949686 Tz (. ) Tj 0.466038 0 Td 60.744235 Tz (One ) Tj 1.487736 0 Td 48.794549 Tz (should ) Tj 2.09717 0 Td 43.31761 Tz (also ) Tj 1.416038 0 Td 49.50584 Tz (confirm ) Tj 2.419811 0 Td 41.077044 Tz (that ) Tj 1.34434 0 Td 44.811321 Tz (the ) Tj 2.186792 0 Td 43.815514 Tz (are ) Tj 1.021698 0 Td 46.802935 Tz (not ) Tj 1.093396 0 Td 45.238095 Tz (limited ) Tj 2.115094 0 Td 40.330189 Tz (to ) Tj 0.55566 0 Td 14.937107 Tz (, ) Tj 0.376415 0 Td 69.308176 Tz (BLAST ) Tj 2.330189 0 Td 52.777778 Tz (and ) Tj 1.200943 0 Td 61.242138 Tz (PILEUP ) Tj 2.186792 0 Td 20.91195 Tz (. ) Tj 64.87395 0 0 64.87395 0 2827.775229 Tm 4.978886 0 Td 37.802245 Tz (correct ) Tj 1.772668 0 Td 37.037637 Tz (substitution ) Tj 2.80544 0 Td 41.533535 Tz (matrix ) Tj 1.680181 0 Td 45.387162 Tz (and ) Tj 0.986528 0 Td 43.674439 Tz (gap ) Tj 0.955699 0 Td 37.679908 Tz (penalties ) Tj 2.219689 0 Td 37.679908 Tz (are ) Tj 0.847798 0 Td 44.31671 Tz (used ) Tj 1.09443 0 Td 10.276339 Tz (. ) Tj 0.339119 0 Td 38.022453 Tz (Opti- ) Tj 2.882513 0 Td 43.032168 Tz (Software ) Tj 2.404663 0 Td 35.967185 Tz (for ) Tj 0.986528 0 Td 42.646805 Tz (performing ) Tj 2.897927 0 Td 60.630397 Tz (BLAST ) Tj 2.127202 0 Td 39.820812 Tz (analyses ) Tj 2.281347 0 Td 28.259931 Tz (is ) Tj 0.678238 0 Td 38.536269 Tz (publicly ) Tj 61.932773 0 0 61.932773 0 2787.80566 Tm 5.199186 0 Td 48.43962 Tz (mal ) Tj 1.097965 0 Td 43.595658 Tz (alignments ) Tj 2.615739 0 Td 26.9109 Tz (, ) Tj 0.41981 0 Td 41.26338 Tz (including ) Tj 2.454274 0 Td 41.039123 Tz (multiple ) Tj 2.163636 0 Td 43.864767 Tz (alignments ) Tj 2.615739 0 Td 26.9109 Tz (, ) Tj 0.387517 0 Td 44.8515 Tz (can ) Tj 1.033379 0 Td 45.74853 Tz (be ) Tj 0.726594 0 Td 42.384668 Tz (pre- ) Tj 2.228223 0 Td 39.76833 Tz (available ) Tj 2.454274 0 Td 44.979647 Tz (through ) Tj 2.179783 0 Td 40.36635 Tz (the ) Tj 1.017232 0 Td 43.05744 Tz (National ) Tj 2.389688 0 Td 44.8515 Tz (Center ) Tj 1.905292 0 Td 38.57229 Tz (for ) Tj 1.001085 0 Td 45.127509 Tz (Biotechnology ) Tj 55.079365 0 0 55.079365 0 2754.021951 Tm 5.827954 0 Td 49.62536 Tz (pared ) Tj 1.779251 0 Td 45.994236 Tz (using ) Tj 1.379827 0 Td 30.259366 Tz (, ) Tj 0.472046 0 Td 37.824207 Tz (e.g. ) Tj 1.016715 0 Td 12.103746 Tz (, ) Tj 0.363112 0 Td 53.458213 Tz (PSI ) Tj 1.016715 0 Td 24.207493 Tz (- ) Tj 0.217867 0 Td 72.017291 Tz (BLAST ) Tj 2.033429 0 Td 24.207493 Tz (. ) Tj 61.269841 0 0 61.269841 0 2741.502469 Tm 20.417876 0 Td 29.92228 Tz (5 ) Tj 0.750777 0 Td 43.276024 Tz (Information ) Tj 2.88886 0 Td 21.761658 Tz (. ) Tj 0.39171 0 Td 43.523316 Tz (This ) Tj 1.322021 0 Td 43.523316 Tz (algorithm ) Tj 2.595078 0 Td 42.163212 Tz (involves ) Tj 2.301295 0 Td 30.466321 Tz (first ) Tj 1.17513 0 Td 40.061234 Tz (identifying ) Tj 2.88886 0 Td 44.88342 Tz (high ) Tj 59.350649 0 0 59.350649 0 2707.73107 Tm 6.082495 0 Td 56.163384 Tz (One ) Tj 1.179431 0 Td 47.738877 Tz (of ) Tj 0.673961 0 Td 34.259664 Tz (skill ) Tj 1.213129 0 Td 39.314369 Tz (in ) Tj 0.606565 0 Td 42.122538 Tz (the ) Tj 0.926696 0 Td 35.570143 Tz (art ) Tj 0.791904 0 Td 39.314369 Tz (will ) Tj 1.112035 0 Td 45.242726 Tz (recognize ) Tj 2.594748 0 Td 38.612327 Tz (that ) Tj 1.078337 0 Td 50.547046 Tz (two ) Tj 1.078337 0 Td 44.462679 Tz (polypeptides ) Tj 61.558442 0 0 61.558442 0 2698.818408 Tm 21.069409 0 Td 41.385373 Tz (scoring ) Tj 1.933122 0 Td 45.349859 Tz (sequence ) Tj 2.339241 0 Td 38.445851 Tz (pairs ) Tj 1.364557 0 Td 21.659634 Tz (\( ) Tj 0.178692 0 Td 54.825949 Tz (HSPs ) Tj 1.348312 0 Td 27.074543 Tz (\) ) Tj 0.341139 0 Td 47.38045 Tz (by ) Tj 0.763502 0 Td 39.873418 Tz (identifying ) Tj 2.826582 0 Td 38.987342 Tz (short ) Tj 1.332068 0 Td 48.734177 Tz (words ) Tj 1.640717 0 Td 46.026723 Tz (of ) Tj 68.571429 0 0 68.571429 0 2660.669988 Tm 4.710417 0 Td 41.319444 Tz (can ) Tj 0.860417 0 Td 37.065972 Tz (also ) Tj 1.064583 0 Td 42.534722 Tz (be ) Tj 0.685417 0 Td 29.166667 Tz ( ) Tj 0.277083 0 Td 34.588675 Tz (substantially ) Tj 2.975 0 Td 34.027778 Tz (identical ) Tj 1.779167 0 Td 34.027778 Tz ( ) Tj 0.39375 0 Td 30.381944 Tz (if ) Tj 0.466667 0 Td 36.458333 Tz (the ) Tj 0.758333 0 Td 47.800926 Tz (two ) Tj 1.035417 0 Td 38.483796 Tz (polypeptides ) Tj 60.38961 0 0 60.38961 0 2653.510373 Tm 21.460645 0 Td 42.777778 Tz (length ) Tj 1.838065 0 Td 93.835125 Tz (W ) Tj 0.877634 0 Td 40.017921 Tz (in ) Tj 0.77828 0 Td 41.397849 Tz (the ) Tj 1.076344 0 Td 45.81362 Tz (query ) Tj 1.722151 0 Td 45.882616 Tz (sequence ) Tj 2.252043 0 Td 19.318996 Tz (, ) Tj 0.447097 0 Td 50.781362 Tz (which ) Tj 1.838065 0 Td 38.637993 Tz (either ) Tj 1.689032 0 Td 50.781362 Tz (match ) Tj 1.838065 0 Td 42.777778 Tz (or ) Tj 60 0 0 60 0 2622.923913 Tm 5.383333 0 Td 40.740741 Tz (are ) Tj 0.933333 0 Td 47.037037 Tz (immunologically ) Tj 4.45 0 Td 41.269841 Tz (similar ) Tj 1.666667 0 Td 19.444444 Tz (. ) Tj 0.333333 0 Td 50 Tz (Thus ) Tj 1.216667 0 Td 25 Tz (, ) Tj 0.35 0 Td 40.47619 Tz (overall ) Tj 1.883333 0 Td 42.460317 Tz (protein ) Tj 1.966667 0 Td 39.814815 Tz (structure ) Tj 60 0 0 60 0 2608.504232 Tm 21.633333 0 Td 37.698413 Tz (satisfy ) Tj 1.766667 0 Td 53.472222 Tz (some ) Tj 1.433333 0 Td 40.972222 Tz (positive ) Tj 2 0 Td 25 Tz (- ) Tj 0.183333 0 Td 46.296296 Tz (valued ) Tj 1.8 0 Td 43.209877 Tz (threshold ) Tj 2.5 0 Td 42.222222 Tz (score ) Tj 1.433333 0 Td 58.333333 Tz (T ) Tj 0.483333 0 Td 56.944444 Tz (when ) Tj 1.516667 0 Td 43.253968 Tz (aligned ) Tj 58.571429 0 0 58.571429 0 2581.313559 Tm 5.497561 0 Td 60.704607 Tz (may ) Tj 1.45122 0 Td 49.796748 Tz (be ) Tj 0.990244 0 Td 41.463415 Tz (similar ) Tj 2.082927 0 Td 46.666667 Tz (while ) Tj 1.758537 0 Td 42.682927 Tz (the ) Tj 1.126829 0 Td 47.96748 Tz (primary ) Tj 2.407317 0 Td 40.785908 Tz (structure ) Tj 2.578049 0 Td 46.95122 Tz (of ) Tj 0.853659 0 Td 42.682927 Tz (the ) Tj 1.126829 0 Td 52.168022 Tz (two ) Tj 57.653061 0 0 57.653061 0 2565.281374 Tm 22.479292 0 Td 48.421829 Tz (with ) Tj 1.35292 0 Td 43.362832 Tz (a ) Tj 0.450973 0 Td 55.648968 Tz (word ) Tj 1.526372 0 Td 49.144543 Tz (of ) Tj 0.693805 0 Td 43.362832 Tz (the ) Tj 1.006018 0 Td 54.20354 Tz (same ) Tj 1.491681 0 Td 44.80826 Tz (length ) Tj 1.803894 0 Td 41.917404 Tz (in ) Tj 0.693805 0 Td 43.362832 Tz (a ) Tj 0.468319 0 Td 45.89233 Tz (database ) Tj 2.428319 0 Td 46.615044 Tz (sequence ) Tj 2.341593 0 Td 20.235988 Tz (. ) Tj 0.346903 0 Td 60.707965 Tz (T ) Tj 0.555044 0 Td 33.244838 Tz (is ) Tj 60 0 0 60 0 2543.093628 Tm 5.35 0 Td 43.981481 Tz (polypeptides ) Tj 3.666667 0 Td 42.063492 Tz (display ) Tj 2.266667 0 Td 38.636364 Tz (significant ) Tj 3.033333 0 Td 39.506173 Tz (variation ) Tj 2.216667 0 Td 19.444444 Tz (. ) Tj 0.616667 0 Td 45.061728 Tz (Therefore ) Tj 2.916667 0 Td 38.888889 Tz (a ) Tj 0.683333 0 Td 34.722222 Tz (10 ) Tj 57.142857 0 0 57.142857 0 2521.119138 Tm 22.68 0 Td 43.385417 Tz (referred ) Tj 2.2925 0 Td 39.375 Tz (to ) Tj 0.735 0 Td 42.291667 Tz (as ) Tj 0.735 0 Td 44.722222 Tz (the ) Tj 1.015 0 Td 50.798611 Tz (neighborhood ) Tj 3.8675 0 Td 56.145833 Tz (word ) Tj 1.5925 0 Td 44.333333 Tz (score ) Tj 1.5575 0 Td 45.046296 Tz (threshold ) Tj 2.73 0 Td 35 Tz (\( ) Tj 0.2275 0 Td 53.472222 Tz (Alt ) Tj 57.142857 0 0 57.142857 0 2496.91195 Tm 5.635 0 Td 54.930556 Tz (method ) Tj 2.205 0 Td 39.375 Tz (to ) Tj 0.735 0 Td 51.666667 Tz (measure ) Tj 2.415 0 Td 50.416667 Tz (whether ) Tj 2.345 0 Td 53.472222 Tz (two ) Tj 1.225 0 Td 46.180556 Tz (polypeptides ) Tj 3.605 0 Td 42.777778 Tz (are ) Tj 1.0675 0 Td 50.416667 Tz (substan ) Tj 61.428571 0 0 61.428571 0 2456.763636 Tm 5.24186 0 Td 34.366925 Tz (tially ) Tj 1.448837 0 Td 38.28596 Tz (identical ) Tj 2.262791 0 Td 42.393411 Tz (involves ) Tj 2.230233 0 Td 46.72696 Tz (measuring ) Tj 2.702326 0 Td 41.602067 Tz (the ) Tj 0.927907 0 Td 44.186047 Tz (binding ) Tj 2.051163 0 Td 46.124031 Tz (of ) Tj 0.586047 0 Td 57.364341 Tz (monoclo ) Tj 62.857143 0 0 62.857143 0 2476.276923 Tm 20.65 0 Td 40.833333 Tz (schul ) Tj 1.4 0 Td 34.469697 Tz (et ) Tj 0.604545 0 Td 33.143939 Tz (al ) Tj 0.445455 0 Td 13.257576 Tz (, ) Tj 0.318182 0 Td 40.30303 Tz (supra ) Tj 1.336364 0 Td 26.515152 Tz (\) ) Tj 0.111364 0 Td 26.515152 Tz (. ) Tj 0.334091 0 Td 46.136364 Tz (These ) Tj 1.575 0 Td 32.19697 Tz (initial ) Tj 1.543182 0 Td 45.959596 Tz (neighborhood ) Tj 3.484091 0 Td 51.041667 Tz (word ) Tj 1.384091 0 Td 34.469697 Tz (hits ) Tj 1.05 0 Td 37.121212 Tz (act ) Tj 61.428571 0 0 61.428571 0 2414.589552 Tm 5.24186 0 Td 39.793282 Tz (nal ) Tj 0.927907 0 Td 42.054264 Tz (or ) Tj 0.651163 0 Td 42.596899 Tz (polyclonal ) Tj 2.767442 0 Td 40.968992 Tz (antibodies ) Tj 2.653488 0 Td 36.627907 Tz (to ) Tj 0.651163 0 Td 46.124031 Tz (each ) Tj 1.269767 0 Td 43.1642 Tz (polypeptide ) Tj 2.865116 0 Td 27.131783 Tz (. ) Tj 0.325581 0 Td 56.976744 Tz (Two ) Tj 1.286047 0 Td 52.906977 Tz (poly ) Tj 60 0 0 60 0 2433.632184 Tm 21.616667 0 Td 40.277778 Tz (as ) Tj 0.7 0 Td 43.333333 Tz (seeds ) Tj 1.516667 0 Td 39.814815 Tz (for ) Tj 0.883333 0 Td 37.222222 Tz (initiating ) Tj 2.45 0 Td 42.708333 Tz (searches ) Tj 2.25 0 Td 37.5 Tz (to ) Tj 0.666667 0 Td 39.583333 Tz (find ) Tj 1.133333 0 Td 43.981481 Tz (longer ) Tj 1.766667 0 Td 56.25 Tz (HSPs ) Tj 1.666667 0 Td 46.031746 Tz (contain ) Tj 64.821429 0 0 64.821429 0 2374.195092 Tm 4.952066 0 Td 39.53168 Tz (peptides ) Tj 2.098072 0 Td 37.710438 Tz (are ) Tj 0.879339 0 Td 36.985237 Tz (substantially ) Tj 3.069972 0 Td 36.282012 Tz (identical ) Tj 2.144353 0 Td 33.425161 Tz (if ) Tj 0.509091 0 Td 38.567493 Tz (the ) Tj 0.879339 0 Td 38.82461 Tz (antibodies ) Tj 2.545455 0 Td 35.996327 Tz (specific ) Tj 55.714286 0 0 55.714286 0 2389.512535 Tm 23.279487 0 Td 45.868946 Tz (ing ) Tj 1.148718 0 Td 45.619658 Tz (them ) Tj 1.346154 0 Td 20.940171 Tz (. ) Tj 0.466667 0 Td 56.837607 Tz (The ) Tj 1.346154 0 Td 57.58547 Tz (word ) Tj 1.687179 0 Td 38.888889 Tz (hits ) Tj 1.292308 0 Td 43.874644 Tz (are ) Tj 1.130769 0 Td 50.106838 Tz (extended ) Tj 2.728205 0 Td 41.880342 Tz (in ) Tj 0.807692 0 Td 50.106838 Tz (both ) Tj 1.525641 0 Td 43.376068 Tz (directions ) Tj 76.168831 0 0 76.168831 0 2337.509114 Tm 4.24058 0 Td 31.363077 Tz (for ) Tj 0.708951 0 Td 37.198068 Tz (a ) Tj 0.367604 0 Td 24.944587 Tz (first ) Tj 0.892754 0 Td 35.208866 Tz (polypeptide ) Tj 2.468201 0 Td 35.009946 Tz (bind ) Tj 1.024041 0 Td 29.539642 Tz (to ) Tj 0.498892 0 Td 32.821824 Tz (a ) Tj 0.367604 0 Td 37.562755 Tz (second ) Tj 1.522933 0 Td 35.009946 Tz (polypeptide ) Tj 2.441944 0 Td 35.009946 Tz (with ) Tj 1.076556 0 Td 31.727764 Tz (an ) Tj 0.761466 0 Td 25.163399 Tz (15 ) Tj 0.630179 0 Td 36.322819 Tz (along ) Tj 1.234101 0 Td 37.745098 Tz (each ) Tj 1.076556 0 Td 36.924552 Tz (sequence ) Tj 1.943052 0 Td 31.363077 Tz (for ) Tj 0.708951 0 Td 33.915885 Tz (as ) Tj 0.551407 0 Td 29.904329 Tz (far ) Tj 0.682694 0 Td 33.915885 Tz (as ) Tj 0.551407 0 Td 34.280572 Tz (the ) Tj 0.761466 0 Td 36.541631 Tz (cumulative ) Tj 2.336914 0 Td 36.225569 Tz (alignment ) Tj 67.142857 0 0 67.142857 0 2288.035191 Tm 4.810638 0 Td 32.269504 Tz (affinity ) Tj 1.861702 0 Td 40.957447 Tz (of ) Tj 0.744681 0 Td 32.269504 Tz (at ) Tj 0.685106 0 Td 33.758865 Tz (least ) Tj 1.310638 0 Td 43.853428 Tz (one ) Tj 1.07234 0 Td 35.248227 Tz (third ) Tj 1.355319 0 Td 42.198582 Tz (of ) Tj 0.744681 0 Td 37.234043 Tz (the ) Tj 0.982979 0 Td 31.95922 Tz (affinity ) Tj 1.846809 0 Td 35.579196 Tz (for ) Tj 0.923404 0 Td 37.234043 Tz (the ) Tj 0.982979 0 Td 28.297872 Tz (first ) Tj 54.285714 0 0 54.285714 0 2304 Tm 23.910526 0 Td 46.666667 Tz (score ) Tj 1.676316 0 Td 52.192982 Tz (can ) Tj 1.160526 0 Td 53.72807 Tz (be ) Tj 0.902632 0 Td 46.393762 Tz (increased ) Tj 2.615789 0 Td 21.491228 Tz (. ) Tj 0.386842 0 Td 50.82846 Tz (Extension ) Tj 3.002632 0 Td 50.657895 Tz (of ) Tj 0.773684 0 Td 46.052632 Tz (the ) Tj 1.086842 0 Td 59.100877 Tz (word ) Tj 1.639474 0 Td 40.679825 Tz (hits ) Tj 1.252632 0 Td 42.982456 Tz (in ) Tj 0.773684 0 Td 51.425439 Tz (each ) Tj 61.428571 0 0 61.428571 0 2253.844444 Tm 5.225581 0 Td 43.410853 Tz (polypeptide ) Tj 2.930233 0 Td 10.852713 Tz (. ) Tj 60.952381 0 0 60.952381 0 2257.411392 Tm 21.278906 0 Td 40.104167 Tz (direction ) Tj 2.411719 0 Td 40.104167 Tz (are ) Tj 0.951562 0 Td 41.927083 Tz (halted ) Tj 1.722656 0 Td 56.054688 Tz (when ) Tj 1.378125 0 Td 10.9375 Tz (: ) Tj 0.344531 0 Td 41.927083 Tz (the ) Tj 1.000781 0 Td 45.117188 Tz (cumulative ) Tj 2.953125 0 Td 44.965278 Tz (alignment ) Tj 2.690625 0 Td 42.109375 Tz (score ) Tj 60 0 0 60 0 2208.670588 Tm 6.016667 0 Td 47.222222 Tz (For ) Tj 1.05 0 Td 46.875 Tz (sequence ) Tj 2.45 0 Td 46.388889 Tz (comparison ) Tj 2.866667 0 Td 27.777778 Tz (, ) Tj 0.366667 0 Td 40.123457 Tz (typically ) Tj 2.383333 0 Td 48.148148 Tz (one ) Tj 1.1 0 Td 46.875 Tz (sequence ) Tj 2.45 0 Td 38.888889 Tz (acts ) Tj 1.15 0 Td 40.277778 Tz (as ) Tj 58.571429 0 0 58.571429 0 2215.750929 Tm 22.143902 0 Td 35.284553 Tz (falls ) Tj 1.229268 0 Td 41.734417 Tz (off ) Tj 0.819512 0 Td 51.219512 Tz (by ) Tj 0.768293 0 Td 42.682927 Tz (the ) Tj 0.921951 0 Td 43.038618 Tz (quantity ) Tj 2.202439 0 Td 73.98374 Tz (X ) Tj 0.614634 0 Td 50.50813 Tz (from ) Tj 1.365854 0 Td 31.300813 Tz (its ) Tj 0.717073 0 Td 61.788618 Tz (maximum ) Tj 2.731707 0 Td 46.95122 Tz (achieved ) Tj 2.390244 0 Td 45.528455 Tz (value ) Tj 1.434146 0 Td 14.227642 Tz (; ) Tj 58.322981 0 0 58.322981 0 2169.024568 Tm 5.538126 0 Td 42.86475 Tz (a ) Tj 0.411502 0 Td 44.134816 Tz (reference ) Tj 2.571885 0 Td 48.58005 Tz (sequence ) Tj 2.314696 0 Td 20.00355 Tz (, ) Tj 0.308626 0 Td 40.0071 Tz (to ) Tj 0.66869 0 Td 52.00923 Tz (which ) Tj 1.697444 0 Td 37.14945 Tz (test ) Tj 1.080192 0 Td 46.992466 Tz (sequences ) Tj 2.726198 0 Td 41.9122 Tz (are ) Tj 0.925879 0 Td 50.723287 Tz (compared ) Tj 2.520447 0 Td 28.5765 Tz (. ) Tj 1.457401 0 Td 42.86475 Tz (the ) Tj 1.114483 0 Td 47.151225 Tz (cumulative ) Tj 3.189137 0 Td 44.00781 Tz (score ) Tj 1.663152 0 Td 47.151225 Tz (goes ) Tj 1.474547 0 Td 40.0071 Tz (to ) Tj 0.840149 0 Td 44.293575 Tz (zero ) Tj 1.42311 0 Td 44.293575 Tz (or ) Tj 0.840149 0 Td 51.4377 Tz (below ) Tj 1.560277 0 Td 14.28825 Tz (, ) Tj 0.462939 0 Td 49.5326 Tz (due ) Tj 1.234505 0 Td 38.578275 Tz (to ) Tj 0.805857 0 Td 43.8173 Tz (the ) Tj 60.714286 0 0 60.714286 0 2127.594476 Tm 5.303529 0 Td 61.078431 Tz (When ) Tj 1.778824 0 Td 44.470588 Tz (using ) Tj 1.68 0 Td 41.176471 Tz (a ) Tj 0.625882 0 Td 45.980392 Tz (sequence ) Tj 2.552941 0 Td 47.764706 Tz (comparison ) Tj 3.211765 0 Td 40.566449 Tz (algorithm ) Tj 2.322353 0 Td 27.45098 Tz (, ) Tj 0.543529 0 Td 35 Tz (test ) Tj 1.185882 0 Td 49.411765 Tz (and ) Tj 1.268235 0 Td 37.058824 Tz (20 ) Tj 0.872941 0 Td 45.980392 Tz (accumulation ) Tj 3.458824 0 Td 46.666667 Tz (of ) Tj 0.642353 0 Td 48.496732 Tz (one ) Tj 1.037647 0 Td 42.54902 Tz (or ) Tj 0.625882 0 Td 52.843137 Tz (more ) Tj 1.416471 0 Td 42.892157 Tz (negative ) Tj 2.174118 0 Td 27.45098 Tz (- ) Tj 0.214118 0 Td 40.392157 Tz (scoring ) Tj 1.844706 0 Td 42.352941 Tz (residue ) Tj 2.042353 0 Td 45.568627 Tz (align ) Tj 57.337662 0 0 57.337662 0 2083.479691 Tm 5.615855 0 Td 44.893251 Tz (reference ) Tj 2.790487 0 Td 47.800008 Tz (sequences ) Tj 2.964892 0 Td 42.63244 Tz (are ) Tj 1.116195 0 Td 45.677614 Tz (entered ) Tj 2.24983 0 Td 40.694602 Tz (into ) Tj 1.342922 0 Td 43.601359 Tz (a ) Tj 0.62786 0 Td 51.594941 Tz (computer ) Tj 2.424236 0 Td 26.160815 Tz (, ) Tj 0.540657 0 Td 45.054738 Tz (subse- ) Tj 2.912571 0 Td 51.158928 Tz (ments ) Tj 1.587089 0 Td 23.254058 Tz (; ) Tj 0.31393 0 Td 45.054738 Tz (or ) Tj 0.680181 0 Td 43.601359 Tz (the ) Tj 0.97667 0 Td 51.352712 Tz (end ) Tj 1.098754 0 Td 47.961495 Tz (of ) Tj 0.680181 0 Td 41.179061 Tz (either ) Tj 1.656852 0 Td 49.051529 Tz (sequence ) Tj 2.528879 0 Td 33.427709 Tz (is ) Tj 0.575538 0 Td 47.338618 Tz (reached ) Tj 2.023103 0 Td 23.254058 Tz (. ) Tj 0.33137 0 Td 54.259469 Tz (The ) Tj 1.168516 0 Td 67.436769 Tz (BLAST ) Tj 61.571429 0 0 61.571429 0 2042.703828 Tm 5.24594 0 Td 46.919309 Tz (quence ) Tj 2.192575 0 Td 41.83365 Tz (coordinates ) Tj 3.280742 0 Td 39.700954 Tz (are ) Tj 1.218097 0 Td 41.95669 Tz (designated ) Tj 2.533643 0 Td 27.068832 Tz (, ) Tj 0.698376 0 Td 33.83604 Tz (if ) Tj 0.828306 0 Td 42.107072 Tz (necessary ) Tj 2.338747 0 Td 18.948183 Tz (, ) Tj 0.617169 0 Td 48.723898 Tz (and ) Tj 2.095128 0 Td 43.310131 Tz (algorithm ) Tj 2.566125 0 Td 43.851508 Tz (parameters ) Tj 2.825986 0 Td 43.310131 Tz (W ) Tj 0.50348 0 Td 21.655066 Tz (, ) Tj 0.341067 0 Td 48.723898 Tz (T ) Tj 0.308585 0 Td 21.655066 Tz (, ) Tj 0.341067 0 Td 48.723898 Tz (and ) Tj 1.071926 0 Td 64.965197 Tz (X ) Tj 0.617169 0 Td 44.513191 Tz (determine ) Tj 2.598608 0 Td 41.505543 Tz (the ) Tj 0.941995 0 Td 37.404204 Tz (sensitivity ) Tj 61.260504 0 0 61.260504 0 2001.254269 Tm 5.272565 0 Td 45.910494 Tz (sequence ) Tj 2.57915 0 Td 43.52995 Tz (algorithm ) Tj 2.726063 0 Td 48.971193 Tz (program ) Tj 2.415912 0 Td 44.346136 Tz (parameters ) Tj 3.052538 0 Td 39.902454 Tz (are ) Tj 1.110014 0 Td 41.897577 Tz (designated ) Tj 2.546502 0 Td 27.206219 Tz (. ) Tj 1.469136 0 Td 48.064319 Tz (and ) Tj 1.077366 0 Td 45.706447 Tz (speed ) Tj 1.567078 0 Td 44.890261 Tz (of ) Tj 0.669273 0 Td 40.809328 Tz (the ) Tj 0.946776 0 Td 45.343698 Tz (alignment ) Tj 2.383265 0 Td 27.206219 Tz (. ) Tj 0.39177 0 Td 50.784941 Tz (The ) Tj 1.126337 0 Td 63.662551 Tz (BLAST ) Tj 2.089438 0 Td 49.359854 Tz (program ) Tj 2.252675 0 Td 39.297871 Tz (typically ) Tj 59.875776 0 0 59.875776 0 1955.730795 Tm 5.377801 0 Td 44.139004 Tz (Default ) Tj 2.187863 0 Td 50.501383 Tz (program ) Tj 2.455083 0 Td 45.371715 Tz (parameters ) Tj 3.106432 0 Td 47.320194 Tz (can ) Tj 1.185788 0 Td 47.320194 Tz (be ) Tj 0.918568 0 Td 48.016079 Tz (used ) Tj 1.185788 0 Td 13.917704 Tz (, ) Tj 0.467635 0 Td 43.144882 Tz (or ) Tj 0.851763 0 Td 39.728719 Tz (alternative ) Tj 3.908091 0 Td 43.840768 Tz (uses ) Tj 1.285996 0 Td 40.361342 Tz (as ) Tj 0.734855 0 Td 40.361342 Tz (defaults ) Tj 2.171162 0 Td 41.753112 Tz (a ) Tj 0.467635 0 Td 53.58316 Tz (word ) Tj 1.503112 0 Td 43.144882 Tz (length ) Tj 1.787033 0 Td 27.835408 Tz (\( ) Tj 0.183714 0 Td 94.640387 Tz (W ) Tj 0.601245 0 Td 27.835408 Tz (\) ) Tj 0.40083 0 Td 47.320194 Tz (of ) Tj 0.768257 0 Td 38.969571 Tz (11 ) Tj 0.567842 0 Td 13.917704 Tz (, ) Tj 0.334025 0 Td 41.753112 Tz (the ) Tj 0.985373 0 Td 66.109094 Tz (BLOSUM62 ) Tj 63.461538 0 0 63.461538 0 1915.044501 Tm 5.073939 0 Td 42.808081 Tz (parameters ) Tj 2.883636 0 Td 45.521886 Tz (can ) Tj 1.087273 0 Td 45.959596 Tz (be ) Tj 0.866667 0 Td 39.919192 Tz (designated ) Tj 2.505455 0 Td 26.262626 Tz (. ) Tj 0.425455 0 Td 49.89899 Tz (The ) Tj 1.229091 0 Td 43.989899 Tz (sequence ) Tj 2.426667 0 Td 45.69697 Tz (comparison ) Tj 3.104242 0 Td 34.141414 Tz (25 ) Tj 0.850909 0 Td 40.1443 Tz (scoring ) Tj 1.859394 0 Td 42.457912 Tz (matrix ) Tj 1.575758 0 Td 13.131313 Tz (, ) Tj 0.283636 0 Td 42.545455 Tz (alignments ) Tj 2.773333 0 Td 26.262626 Tz (\( ) Tj 0.173333 0 Td 57.777778 Tz (B ) Tj 0.393939 0 Td 26.262626 Tz (\) ) Tj 0.362424 0 Td 43.333333 Tz (of ) Tj 0.661818 0 Td 45.959596 Tz (50 ) Tj 0.58303 0 Td 13.131313 Tz (, ) Tj 0.299394 0 Td 40.826446 Tz (expectation ) Tj 2.883636 0 Td 26.262626 Tz (\( ) Tj 0.189091 0 Td 55.151515 Tz (E ) Tj 0.362424 0 Td 26.262626 Tz (\) ) Tj 0.346667 0 Td 44.646465 Tz (of ) Tj 0.693333 0 Td 43.333333 Tz (10 ) Tj 0.567273 0 Td 13.131313 Tz (, ) Tj 60.434783 0 0 60.434783 0 1871.539106 Tm 5.344604 0 Td 44.1247 Tz (algorithm ) Tj 2.548201 0 Td 44.814149 Tz (then ) Tj 1.241007 0 Td 39.98801 Tz (calculates ) Tj 2.581295 0 Td 41.366906 Tz (the ) Tj 0.926619 0 Td 42.942789 Tz (percent ) Tj 2.002158 0 Td 46.53777 Tz (sequence ) Tj 2.415827 0 Td 37.230216 Tz (identities ) Tj 2.432374 0 Td 39.528377 Tz (for ) Tj 1.969065 0 Td 88.2494 Tz (M ) Tj 0.546043 0 Td 55.155875 Tz (= ) Tj 0.364029 0 Td 38.609113 Tz (5 ) Tj 0.314388 0 Td 13.788969 Tz (, ) Tj 0.330935 0 Td 74.460432 Tz (N ) Tj 0.463309 0 Td 55.155875 Tz (= ) Tj 0.364029 0 Td 48.261391 Tz (-4 ) Tj 0.645324 0 Td 13.788969 Tz (, ) Tj 0.347482 0 Td 48.721023 Tz (and ) Tj 1.092086 0 Td 41.366906 Tz (a ) Tj 0.496403 0 Td 47.709832 Tz (comparison ) Tj 3.094245 0 Td 45.503597 Tz (of ) Tj 0.694964 0 Td 46.193046 Tz (both ) Tj 1.340288 0 Td 41.366906 Tz (strands ) Tj 1.73741 0 Td 19.304556 Tz (. ) Tj 57.142857 0 0 57.142857 0 1832.834805 Tm 5.635 0 Td 43.75 Tz (the ) Tj 0.9975 0 Td 37.916667 Tz (test ) Tj 1.155 0 Td 47.962963 Tz (sequences ) Tj 2.8175 0 Td 40.46875 Tz (relative ) Tj 2.1525 0 Td 40.833333 Tz (to ) Tj 0.7175 0 Td 43.75 Tz (the ) Tj 0.9975 0 Td 44.722222 Tz (reference ) Tj 2.66 0 Td 48.489583 Tz (sequence ) Tj 2.38 0 Td 20.416667 Tz (, ) Tj 0.35 0 Td 50.166667 Tz (based ) Tj 62.857143 0 0 62.857143 0 1821.563543 Tm 21.222727 0 Td 50.378788 Tz (The ) Tj 1.081818 0 Td 62.045455 Tz (BLAST ) Tj 2.020455 0 Td 42.424242 Tz (algorithm ) Tj 2.465909 0 Td 37.784091 Tz (also ) Tj 1.097727 0 Td 44.081439 Tz (performs ) Tj 2.306818 0 Td 39.772727 Tz (a ) Tj 0.429545 0 Td 33.264463 Tz (statistical ) Tj 2.386364 0 Td 39.109848 Tz (analysis ) Tj 57.714286 0 0 57.714286 0 1794.637795 Tm 5.596535 0 Td 53.424092 Tz (on ) Tj 0.84901 0 Td 43.316832 Tz (the ) Tj 1.00495 0 Td 52.392739 Tz (program ) Tj 2.408416 0 Td 47.070957 Tz (parameters ) Tj 2.858911 0 Td 25.990099 Tz (. ) Tj 59.571429 0 0 59.571429 0 1778.028387 Tm 21.772182 0 Td 47.56195 Tz (of ) Tj 0.755396 0 Td 41.966427 Tz (the ) Tj 1.040767 0 Td 39.448441 Tz (similarity ) Tj 2.618705 0 Td 49.960032 Tz (between ) Tj 2.35012 0 Td 50.359712 Tz (two ) Tj 1.22542 0 Td 46.940226 Tz (sequences ) Tj 2.534772 0 Td 19.584333 Tz (. ) Tj 0.402878 0 Td 55.955236 Tz (One ) Tj 1.275779 0 Td 49.560352 Tz (measure ) Tj 2.35012 0 Td 47.56195 Tz (of ) Tj 56.785714 0 0 56.785714 0 1751.747638 Tm 6.322013 0 Td 79.245283 Tz (A ) Tj 0.669182 0 Td 17.610063 Tz ( ) Tj 0.158491 0 Td 53.12369 Tz (comparison ) Tj 3.433962 0 Td 53.319357 Tz (window ) Tj 2.130818 0 Td 26.415094 Tz ( ) Tj 0.264151 0 Td 26.415094 Tz (, ) Tj 0.405031 0 Td 42.557652 Tz (as ) Tj 0.757233 0 Td 50.628931 Tz (used ) Tj 1.426415 0 Td 43.535989 Tz (herein ) Tj 1.620126 0 Td 26.415094 Tz (, ) Tj 0.440252 0 Td 44.75891 Tz (includes ) Tj 2.447799 0 Td 48.134172 Tz (refer ) Tj 62.222222 0 0 62.222222 0 1737.143213 Tm 20.844643 0 Td 37.767857 Tz (similarity ) Tj 2.442857 0 Td 44.53125 Tz (provided ) Tj 2.298214 0 Td 49.553571 Tz (by ) Tj 0.771429 0 Td 40.178571 Tz (the ) Tj 0.916071 0 Td 62.142857 Tz (BLAST ) Tj 2.057143 0 Td 42.857143 Tz (algorithm ) Tj 2.491071 0 Td 30.803571 Tz (is ) Tj 0.5625 0 Td 40.178571 Tz (the ) Tj 0.932143 0 Td 39.84375 Tz (smallest ) Tj 57.362637 0 0 57.362637 0 1709.8 Tm 5.61341 0 Td 48.666986 Tz (ence ) Tj 1.394636 0 Td 39.224138 Tz (to ) Tj 0.732184 0 Td 43.582375 Tz (a ) Tj 0.522989 0 Td 50.63857 Tz (segment ) Tj 2.370881 0 Td 47.940613 Tz (of ) Tj 0.749617 0 Td 50.361856 Tz (any ) Tj 1.150575 0 Td 50.361856 Tz (one ) Tj 1.150575 0 Td 49.393359 Tz (of ) Tj 0.732184 0 Td 44.550873 Tz (the ) Tj 1.011111 0 Td 55.688591 Tz (number ) Tj 2.231418 0 Td 47.940613 Tz (of ) Tj 0.749617 0 Td 47.068966 Tz (contiguous ) Tj 3.259962 0 Td 39.224138 Tz (30 ) Tj 59.047619 0 0 59.047619 0 1692.924812 Tm 21.965323 0 Td 56.451613 Tz (sum ) Tj 1.202419 0 Td 41.825513 Tz (probability ) Tj 2.980645 0 Td 28.225806 Tz (\( ) Tj 0.203226 0 Td 53.629032 Tz (P ) Tj 0.355645 0 Td 28.225806 Tz (\( ) Tj 0.18629 0 Td 76.209677 Tz (N ) Tj 0.474194 0 Td 28.225806 Tz (\) ) Tj 0.203226 0 Td 28.225806 Tz (\) ) Tj 0.237097 0 Td 14.112903 Tz (, ) Tj 0.287903 0 Td 51.935484 Tz (which ) Tj 1.727419 0 Td 45.16129 Tz (provides ) Tj 2.370968 0 Td 49.395161 Tz (an ) Tj 0.779032 0 Td 42.056452 Tz (indication ) Tj 2.709677 0 Td 47.983871 Tz (of ) Tj 0.677419 0 Td 43.27957 Tz (the ) Tj 58.571429 0 0 58.571429 0 1668.296248 Tm 5.497561 0 Td 42.366757 Tz (positions ) Tj 2.560976 0 Td 42.327236 Tz (selected ) Tj 2.253659 0 Td 51.219512 Tz (from ) Tj 1.45122 0 Td 42.682927 Tz (the ) Tj 1.007317 0 Td 48.373984 Tz (group ) Tj 1.707317 0 Td 42.682927 Tz (consisting ) Tj 2.817073 0 Td 46.95122 Tz (of ) Tj 0.75122 0 Td 50.50813 Tz (from ) Tj 1.45122 0 Td 51.219512 Tz (20 ) Tj 0.836585 0 Td 39.837398 Tz (to ) Tj 61.269841 0 0 61.269841 0 1646.346859 Tm 21.13601 0 Td 40.308526 Tz (probability ) Tj 2.937824 0 Td 50.323834 Tz (by ) Tj 0.881347 0 Td 50.051813 Tz (which ) Tj 1.762694 0 Td 40.803109 Tz (a ) Tj 0.52228 0 Td 50.051813 Tz (match ) Tj 1.762694 0 Td 48.57513 Tz (between ) Tj 2.301295 0 Td 48.963731 Tz (two ) Tj 1.17513 0 Td 42.163212 Tz (nucleotide ) Tj 2.823575 0 Td 42.163212 Tz (or ) Tj 58.571429 0 0 58.571429 0 1624.519531 Tm 5.531707 0 Td 51.219512 Tz (600 ) Tj 0.956098 0 Td 14.227642 Tz (, ) Tj 0.307317 0 Td 43.495935 Tz (usually ) Tj 2.031707 0 Td 46.666667 Tz (about ) Tj 1.604878 0 Td 49.796748 Tz (50 ) Tj 0.785366 0 Td 38.414634 Tz (to ) Tj 0.682927 0 Td 46.666667 Tz (about ) Tj 1.604878 0 Td 51.219512 Tz (200 ) Tj 0.973171 0 Td 14.227642 Tz (, ) Tj 0.290244 0 Td 54.776423 Tz (more ) Tj 1.485366 0 Td 43.902439 Tz (usually ) Tj 2.04878 0 Td 46.097561 Tz (about ) Tj 1.639024 0 Td 48.373984 Tz (100 ) Tj 61.285714 0 0 61.285714 0 1584.273684 Tm 5.254079 0 Td 36.713287 Tz (to ) Tj 0.734266 0 Td 44.599845 Tz (about ) Tj 1.648019 0 Td 46.231546 Tz (150 ) Tj 1.142191 0 Td 35.353535 Tz (in ) Tj 0.668998 0 Td 48.407148 Tz (which ) Tj 1.745921 0 Td 27.195027 Tz (a ) Tj 0.522145 0 Td 45.891608 Tz (sequence ) Tj 2.447552 0 Td 58.016058 Tz (may ) Tj 1.289044 0 Td 47.591298 Tz (be ) Tj 0.832168 0 Td 49.630925 Tz (compared ) Tj 55.714286 0 0 55.714286 0 1605.083024 Tm 23.279487 0 Td 54.444444 Tz (amino ) Tj 1.848718 0 Td 46.367521 Tz (acid ) Tj 1.310256 0 Td 49.192783 Tz (sequences ) Tj 2.853846 0 Td 56.239316 Tz (would ) Tj 1.866667 0 Td 49.059829 Tz (occur ) Tj 1.633333 0 Td 55.34188 Tz (by ) Tj 0.861538 0 Td 49.358974 Tz (chance ) Tj 1.848718 0 Td 20.940171 Tz (. ) Tj 0.358974 0 Td 50.854701 Tz (For ) Tj 1.094872 0 Td 53.846154 Tz (example ) Tj 2.207692 0 Td 29.91453 Tz (, ) Tj 55.857143 0 0 55.857143 0 1559.918575 Tm 23.219949 0 Td 44.757033 Tz (a ) Tj 0.465473 0 Td 45.609548 Tz (nucleic ) Tj 2.148338 0 Td 46.248934 Tz (acid ) Tj 1.324808 0 Td 32.821824 Tz (is ) Tj 0.644501 0 Td 48.039216 Tz (considered ) Tj 3.11509 0 Td 43.478261 Tz (similar ) Tj 2.005115 0 Td 41.773231 Tz (to ) Tj 0.734015 0 Td 44.757033 Tz (a ) Tj 0.483376 0 Td 46.083168 Tz (reference ) Tj 2.721228 0 Td 50.351662 Tz (sequence ) Tj 54.761905 0 0 54.761905 0 1544.621921 Tm 5.88 0 Td 47.004831 Tz (reference ) Tj 2.775652 0 Td 50.978261 Tz (sequence ) Tj 2.666087 0 Td 51.73913 Tz (of ) Tj 0.748696 0 Td 45.652174 Tz (the ) Tj 1.05913 0 Td 56.304348 Tz (same ) Tj 1.552174 0 Td 58.333333 Tz (number ) Tj 2.30087 0 Td 51.73913 Tz (of ) Tj 0.766957 0 Td 49 Tz (contiguous ) Tj 3.177391 0 Td 57.826087 Tz (posi ) Tj 60 0 0 60 0 1499.362637 Tm 5.366667 0 Td 39.444444 Tz (tions ) Tj 1.4 0 Td 37.777778 Tz (after ) Tj 1.283333 0 Td 41.666667 Tz (the ) Tj 0.933333 0 Td 50 Tz (two ) Tj 1.133333 0 Td 45.679012 Tz (sequences ) Tj 2.683333 0 Td 40.740741 Tz (are ) Tj 0.916667 0 Td 43.82716 Tz (optimally ) Tj 2.566667 0 Td 42.460317 Tz (aligned ) Tj 1.783333 0 Td 27.777778 Tz (. ) Tj 0.35 0 Td 61.805556 Tz (When ) Tj 1.666667 0 Td 41.666667 Tz (a ) Tj 0.65 0 Td 36.111111 Tz (35 ) Tj 62.857143 0 0 62.857143 0 1513.986894 Tm 20.634091 0 Td 33.143939 Tz (if ) Tj 0.556818 0 Td 39.772727 Tz (the ) Tj 0.970455 0 Td 39.772727 Tz (smallest ) Tj 2.163636 0 Td 53.030303 Tz (sum ) Tj 1.161364 0 Td 39.53168 Tz (probability ) Tj 2.831818 0 Td 38.44697 Tz (in ) Tj 0.684091 0 Td 39.772727 Tz (a ) Tj 0.461364 0 Td 46.136364 Tz (comparison ) Tj 2.990909 0 Td 45.075758 Tz (of ) Tj 0.684091 0 Td 39.772727 Tz (the ) Tj 0.938636 0 Td 34.469697 Tz (test ) Tj 47.142857 0 0 47.142857 0 1477 Tm 27.490909 0 Td 53.535354 Tz (nucleic ) Tj 2.545455 0 Td 54.79798 Tz (acid ) Tj 1.548485 0 Td 49.494949 Tz (to ) Tj 0.869697 0 Td 53.030303 Tz (the ) Tj 1.209091 0 Td 54.601571 Tz (reference ) Tj 3.20303 0 Td 53.535354 Tz (nucleic ) Tj 2.545455 0 Td 54.79798 Tz (acid ) Tj 1.569697 0 Td 38.888889 Tz (is ) Tj 0.784848 0 Td 46.843434 Tz (less ) Tj 1.4 0 Td 57.449495 Tz (than ) Tj 1.633333 0 Td 57.979798 Tz (about ) Tj 61.428571 0 0 61.428571 0 1456.425648 Tm 5.25814 0 Td 27.131783 Tz (" ) Tj 0.35814 0 Td 45.852713 Tz (comparison ) Tj 3.076744 0 Td 57.428941 Tz (window ) Tj 2.116279 0 Td 16.27907 Tz ( ) Tj 0.455814 0 Td 29.844961 Tz (is ) Tj 0.716279 0 Td 46.802326 Tz (used ) Tj 1.448837 0 Td 36.627907 Tz (to ) Tj 0.813953 0 Td 44.61671 Tz (determine ) Tj 2.751163 0 Td 40.697674 Tz (the ) Tj 1.074419 0 Td 42.635659 Tz (percent ) Tj 60 0 0 60 0 1416.021519 Tm 5.383333 0 Td 39.236111 Tz (identity ) Tj 2.066667 0 Td 49.603175 Tz (between ) Tj 2.25 0 Td 50 Tz (two ) Tj 1.133333 0 Td 45.37037 Tz (sequences ) Tj 2.533333 0 Td 19.444444 Tz (, ) Tj 0.316667 0 Td 41.666667 Tz (a ) Tj 0.433333 0 Td 47.222222 Tz (lower ) Tj 1.6 0 Td 38.333333 Tz (limit ) Tj 1.35 0 Td 51.388889 Tz (on ) Tj 0.783333 0 Td 41.666667 Tz (the ) Tj 0.95 0 Td 43.055556 Tz (length ) Tj 57.142857 0 0 57.142857 0 1428.621232 Tm 22.6975 0 Td 42.777778 Tz (0.2 ) Tj 0.84 0 Td 14.583333 Tz (, ) Tj 0.3325 0 Td 55.416667 Tz (more ) Tj 1.54 0 Td 44.625 Tz (preferably ) Tj 2.9225 0 Td 38.645833 Tz (less ) Tj 1.1725 0 Td 46.666667 Tz (than ) Tj 1.3475 0 Td 47.25 Tz (about ) Tj 1.645 0 Td 43.75 Tz (0.01 ) Tj 1.1725 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 51.527778 Tz (and ) Tj 1.1375 0 Td 52.5 Tz (most ) Tj 1.54 0 Td 47.152778 Tz (prefer ) Tj 60 0 0 60 0 1375.877778 Tm 5.383333 0 Td 47.222222 Tz (of ) Tj 0.65 0 Td 41.666667 Tz (the ) Tj 0.916667 0 Td 48.333333 Tz (comparison ) Tj 3.033333 0 Td 55.555556 Tz (window ) Tj 2.166667 0 Td 48.148148 Tz (can ) Tj 1 0 Td 48.611111 Tz (be ) Tj 0.75 0 Td 49.603175 Tz (imposed ) Tj 2.083333 0 Td 27.777778 Tz (, ) Tj 0.333333 0 Td 34.722222 Tz (e.g. ) Tj 0.916667 0 Td 13.888889 Tz (, ) Tj 0.283333 0 Td 41.666667 Tz (a ) Tj 0.4 0 Td 57.539683 Tz (minimum ) Tj 56.190476 0 0 56.190476 0 1384.947826 Tm 23.064407 0 Td 46.716102 Tz (ably ) Tj 1.370339 0 Td 39.300847 Tz (less ) Tj 1.192373 0 Td 48.199153 Tz (than ) Tj 1.388136 0 Td 48.644068 Tz (about ) Tj 1.708475 0 Td 46.271186 Tz (0.001 ) Tj 1.530508 0 Td 11.864407 Tz (. ) Tj 57.142857 0 0 57.142857 0 1331.105498 Tm 5.6525 0 Td 45.208333 Tz (length ) Tj 1.82 0 Td 49.583333 Tz (of ) Tj 0.735 0 Td 52.5 Tz (20 ) Tj 0.6825 0 Td 14.583333 Tz (, ) Tj 0.3325 0 Td 51.041667 Tz (30 ) Tj 0.665 0 Td 14.583333 Tz (, ) Tj 0.3325 0 Td 52.5 Tz (40 ) Tj 0.665 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 51.041667 Tz (50 ) Tj 0.665 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 51.041667 Tz (60 ) Tj 0.6475 0 Td 14.583333 Tz (, ) Tj 0.3325 0 Td 52.5 Tz (70 ) Tj 0.6825 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 49.583333 Tz (80 ) Tj 0.6475 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 51.041667 Tz (90 ) Tj 0.665 0 Td 14.583333 Tz (, ) Tj 0.385 0 Td 49.583333 Tz (100 ) Tj 0.945 0 Td 14.583333 Tz (, ) Tj 0.385 0 Td 48.611111 Tz (110 ) Tj 0.91 0 Td 14.583333 Tz (, ) Tj 0.385 0 Td 50.555556 Tz (120 ) Tj 0.9625 0 Td 14.583333 Tz (, ) Tj 0.385 0 Td 49.583333 Tz (130 ) Tj 0.945 0 Td 14.583333 Tz (, ) Tj 60 0 0 60 0 1342.776786 Tm 22.233333 0 Td 27.777778 Tz ( ) Tj 0.266667 0 Td 44.84127 Tz (Conservatively ) Tj 3.933333 0 Td 46.180556 Tz (modified ) Tj 2.366667 0 Td 41.666667 Tz (variants ) Tj 2.1 0 Td 22.222222 Tz (" ) Tj 0.316667 0 Td 40.873016 Tz (applies ) Tj 1.9 0 Td 37.5 Tz (to ) Tj 0.633333 0 Td 46.527778 Tz (both ) Tj 1.283333 0 Td 50 Tz (amino ) Tj 60.210084 0 0 60.210084 0 1295.565643 Tm 5.397767 0 Td 47.98015 Tz (140 ) Tj 0.89686 0 Td 13.840428 Tz (, ) Tj 0.33217 0 Td 47.057455 Tz (150 ) Tj 0.89686 0 Td 13.840428 Tz (, ) Tj 0.33217 0 Td 47.057455 Tz (160 ) Tj 0.89686 0 Td 13.840428 Tz (, ) Tj 0.315562 0 Td 47.98015 Tz (170 ) Tj 0.913468 0 Td 13.840428 Tz (, ) Tj 0.315562 0 Td 47.98015 Tz (180 ) Tj 0.89686 0 Td 13.840428 Tz (, ) Tj 0.33217 0 Td 47.057455 Tz (190 ) Tj 0.89686 0 Td 13.840428 Tz (, ) Tj 0.282345 0 Td 49.825541 Tz (200 ) Tj 0.946685 0 Td 13.840428 Tz (, ) Tj 0.282345 0 Td 49.825541 Tz (210 ) Tj 0.946685 0 Td 13.840428 Tz (, ) Tj 0.265736 0 Td 50.748236 Tz (220 ) Tj 0.963294 0 Td 13.840428 Tz (, ) Tj 0.265736 0 Td 50.748236 Tz (230 ) Tj 0.946685 0 Td 13.840428 Tz (, ) Tj 0.282345 0 Td 49.825541 Tz (240 ) Tj 1.062945 0 Td 42.905327 Tz (or ) Tj 0.664341 0 Td 49.825541 Tz (250 ) Tj 1.295464 0 Td 38.753198 Tz (40 ) Tj 0.89686 0 Td 42.905327 Tz (acid ) Tj 1.245639 0 Td 48.902846 Tz (and ) Tj 1.079553 0 Td 42.312166 Tz (nucleic ) Tj 2.026239 0 Td 42.213305 Tz (acid ) Tj 1.245639 0 Td 45.212065 Tz (sequences ) Tj 2.507886 0 Td 19.376599 Tz (. ) Tj 0.348779 0 Td 50.517562 Tz (With ) Tj 1.411724 0 Td 41.521284 Tz (respect ) Tj 1.959805 0 Td 38.753198 Tz (to ) Tj 0.697558 0 Td 39.860433 Tz (particular ) Tj 63.193277 0 0 63.193277 0 1251.679697 Tm 5.111303 0 Td 48.000887 Tz (amino ) Tj 1.693218 0 Td 39.033688 Tz (acids ) Tj 1.250133 0 Td 10.549645 Tz (. ) Tj 0.28484 0 Td 40.169804 Tz (Alternatively ) Tj 3.069947 0 Td 26.374113 Tz (, ) Tj 0.379787 0 Td 41.068262 Tz (percent ) Tj 1.962234 0 Td 37.253435 Tz (identity ) Tj 2.025532 0 Td 44.835993 Tz (can ) Tj 1.012766 0 Td 46.154699 Tz (be ) Tj 0.791223 0 Td 41.445035 Tz (defined ) Tj 2.927527 0 Td 39.937943 Tz (nucleic ) Tj 2.025532 0 Td 40.879876 Tz (acid ) Tj 1.313431 0 Td 43.66381 Tz (sequences ) Tj 2.37367 0 Td 18.461879 Tz (, ) Tj 0.474734 0 Td 40.691489 Tz (conservatively ) Tj 3.734574 0 Td 44.17664 Tz (modified ) Tj 2.421144 0 Td 38.572141 Tz (variants ) Tj 58.571429 0 0 58.571429 0 1209.235732 Tm 5.531707 0 Td 47.662602 Tz (such ) Tj 1.314634 0 Td 39.126016 Tz (that ) Tj 1.109756 0 Td 42.682927 Tz (the ) Tj 0.956098 0 Td 56.436314 Tz (window ) Tj 2.236585 0 Td 48.373984 Tz (of ) Tj 0.7 0 Td 49.512195 Tz (comparison ) Tj 3.141463 0 Td 46.95122 Tz (over ) Tj 1.297561 0 Td 51.788618 Tz (which ) Tj 1.72439 0 Td 42.682927 Tz (the ) Tj 0.939024 0 Td 44.715447 Tz (percent ) Tj 50 0 0 50 0 1214 Tm 25.92 0 Td 46.666667 Tz (refers ) Tj 2.1 0 Td 46.666667 Tz (to ) Tj 1 0 Td 52 Tz (those ) Tj 1.98 0 Td 50.952381 Tz (nucleic ) Tj 2.6 0 Td 49.333333 Tz (acids ) Tj 1.92 0 Td 60.666667 Tz (which ) Tj 2.24 0 Td 58.333333 Tz (encode ) Tj 2.54 0 Td 46.666667 Tz (identical ) Tj 2.98 0 Td 51.666667 Tz (or ) Tj 60.714286 0 0 60.714286 0 1165.3765 Tm 5.32 0 Td 38.77451 Tz (identity ) Tj 2.009412 0 Td 38.431373 Tz (criterion ) Tj 2.207059 0 Td 31.568627 Tz (is ) Tj 0.56 0 Td 36.906318 Tz (satisfied ) Tj 2.108235 0 Td 50.098039 Tz (must ) Tj 1.350588 0 Td 42.352941 Tz (include ) Tj 1.943529 0 Td 41.176471 Tz (a ) Tj 0.411765 0 Td 36.784314 Tz (sufficient ) Tj 2.355294 0 Td 50.784314 Tz (amount ) Tj 3.096471 0 Td 38.930481 Tz (essentially ) Tj 2.898824 0 Td 38.431373 Tz (identical ) Tj 2.421176 0 Td 49.960784 Tz (amino ) Tj 1.828235 0 Td 42.54902 Tz (acid ) Tj 1.350588 0 Td 45.446623 Tz (sequences ) Tj 2.454118 0 Td 19.215686 Tz (, ) Tj 0.477647 0 Td 42.54902 Tz (or ) Tj 0.790588 0 Td 49.960784 Tz (where ) Tj 1.795294 0 Td 42.091503 Tz (the ) Tj 57.006803 0 0 57.006803 0 1126.030504 Tm 5.66599 0 Td 49.701671 Tz (of ) Tj 0.789379 0 Td 43.854415 Tz (the ) Tj 1.034964 0 Td 45.153805 Tz (reference ) Tj 2.736516 0 Td 48.970764 Tz (sequence ) Tj 2.613723 0 Td 40.930788 Tz (to ) Tj 0.771838 0 Td 45.942721 Tz (possess ) Tj 2.245346 0 Td 56.279833 Tz (some ) Tj 1.613842 0 Td 62.857995 Tz (FHB1 ) Tj 1.859427 0 Td 40.565334 Tz (activity ) Tj 1.964678 0 Td 11.694511 Tz (. ) Tj 1.438425 0 Td 44.272076 Tz (nucleic ) Tj 2.175179 0 Td 45.316229 Tz (acid ) Tj 1.368258 0 Td 48.239857 Tz (does ) Tj 1.455967 0 Td 46.778043 Tz (not ) Tj 1.122673 0 Td 51.163484 Tz (encode ) Tj 2.140095 0 Td 49.701671 Tz (an ) Tj 0.877088 0 Td 53.210024 Tz (amino ) Tj 1.912053 0 Td 45.316229 Tz (acid ) Tj 1.3858 0 Td 48.239857 Tz (sequence ) Tj 2.368138 0 Td 20.465394 Tz (, ) Tj 0.438544 0 Td 39.468974 Tz (to ) Tj 60 0 0 60 0 1085.211692 Tm 5.383333 0 Td 50.694444 Tz (Thus ) Tj 1.2 0 Td 25 Tz (, ) Tj 0.416667 0 Td 34.722222 Tz (if ) Tj 0.566667 0 Td 50 Tz (two ) Tj 1.166667 0 Td 45.987654 Tz (sequences ) Tj 2.733333 0 Td 37.698413 Tz (satisfy ) Tj 1.833333 0 Td 41.666667 Tz (a ) Tj 0.466667 0 Td 57.539683 Tz (minimum ) Tj 2.616667 0 Td 43.650794 Tz (percent ) Tj 2.066667 0 Td 39.236111 Tz (identity ) Tj 2.266667 0 Td 37.5 Tz (45 ) Tj 0.9 0 Td 39.393939 Tz (essentially ) Tj 2.85 0 Td 39.197531 Tz (identical ) Tj 2.383333 0 Td 46.296296 Tz (sequences ) Tj 2.5 0 Td 19.444444 Tz (. ) Tj 0.383333 0 Td 48.809524 Tz (Because ) Tj 2.3 0 Td 47.222222 Tz (of ) Tj 0.716667 0 Td 41.666667 Tz (the ) Tj 1 0 Td 46.666667 Tz (degeneracy ) Tj 61.885714 0 0 61.885714 0 1042.576031 Tm 5.219298 0 Td 37.703909 Tz (criterion ) Tj 2.278393 0 Td 26.931363 Tz (\( ) Tj 0.177747 0 Td 34.337488 Tz (e.g. ) Tj 0.888735 0 Td 13.465682 Tz (, ) Tj 0.355494 0 Td 35.010773 Tz (at ) Tj 0.646353 0 Td 36.088027 Tz (least ) Tj 1.341182 0 Td 45.783318 Tz (90 ) Tj 0.581717 0 Td 78.100954 Tz (% ) Tj 0.727147 0 Td 45.446676 Tz (sequence ) Tj 2.423823 0 Td 37.367267 Tz (identity ) Tj 1.842105 0 Td 26.931363 Tz (\) ) Tj 0.420129 0 Td 43.090182 Tz (only ) Tj 1.276547 0 Td 44.43675 Tz (over ) Tj 1.292705 0 Td 40.397045 Tz (a ) Tj 1.486611 0 Td 45.783318 Tz (of ) Tj 0.646353 0 Td 40.397045 Tz (the ) Tj 0.904894 0 Td 40.781779 Tz (genetic ) Tj 1.906741 0 Td 46.456602 Tz (code ) Tj 1.163435 0 Td 13.465682 Tz (, ) Tj 0.290859 0 Td 40.397045 Tz (a ) Tj 0.420129 0 Td 39.319791 Tz (large ) Tj 1.341182 0 Td 51.618447 Tz (number ) Tj 2.019852 0 Td 45.783318 Tz (of ) Tj 0.662512 0 Td 40.172617 Tz (functionally ) Tj 3.070175 0 Td 38.302384 Tz (identical ) Tj 58.571429 0 0 58.571429 0 1000.285065 Tm 5.497561 0 Td 56.910569 Tz (window ) Tj 2.270732 0 Td 48.373984 Tz (of ) Tj 0.734146 0 Td 49.512195 Tz (comparison ) Tj 3.158537 0 Td 39.837398 Tz (that ) Tj 1.160976 0 Td 32.723577 Tz (is ) Tj 0.631707 0 Td 37.703252 Tz (less ) Tj 1.126829 0 Td 46.239837 Tz (than ) Tj 1.297561 0 Td 42.682927 Tz (the ) Tj 0.990244 0 Td 39.837398 Tz (entire ) Tj 1.656098 0 Td 44.105691 Tz (length ) Tj 1.792683 0 Td 48.373984 Tz (of ) Tj 1.809756 0 Td 43.089431 Tz (nucleic ) Tj 2.134146 0 Td 42.113821 Tz (acids ) Tj 1.570732 0 Td 49.796748 Tz (encode ) Tj 2.082927 0 Td 49.322493 Tz (any ) Tj 1.178049 0 Td 47.235772 Tz (given ) Tj 1.673171 0 Td 41.869919 Tz (protein ) Tj 1.792683 0 Td 28.455285 Tz (. ) Tj 0.460976 0 Td 49.322493 Tz (For ) Tj 1.160976 0 Td 42.327236 Tz (instance ) Tj 2.04878 0 Td 25.609756 Tz (, ) Tj 0.443902 0 Td 43.631436 Tz (the ) Tj 57.2 0 0 57.2 0 958.108306 Tm 5.629371 0 Td 43.706294 Tz (the ) Tj 1.031469 0 Td 52.447552 Tz (amino ) Tj 1.835664 0 Td 45.16317 Tz (acid ) Tj 1.311189 0 Td 49.16958 Tz (sequence ) Tj 2.56993 0 Td 50.262238 Tz (used ) Tj 1.416084 0 Td 42.249417 Tz (as ) Tj 0.751748 0 Td 43.706294 Tz (a ) Tj 0.48951 0 Td 44.677545 Tz (reference ) Tj 2.674825 0 Td 29.137529 Tz (\( ) Tj 0.192308 0 Td 37.15035 Tz (e.g. ) Tj 0.961538 0 Td 14.568765 Tz (, ) Tj 0.367133 0 Td 66.045066 Tz (SEQ ) Tj 1.433566 0 Td 53.904429 Tz (ID ) Tj 2.01049 0 Td 50.019425 Tz (codons ) Tj 2.097902 0 Td 75.757576 Tz (GCA ) Tj 1.398601 0 Td 14.568765 Tz (, ) Tj 0.384615 0 Td 72.843823 Tz (GCC ) Tj 1.363636 0 Td 14.568765 Tz (, ) Tj 0.367133 0 Td 75.757576 Tz (GCG ) Tj 1.625874 0 Td 51.476301 Tz (and ) Tj 1.188811 0 Td 75.757576 Tz (GCU ) Tj 1.608392 0 Td 33.993784 Tz (all ) Tj 0.891608 0 Td 50.990676 Tz (encode ) Tj 2.08042 0 Td 43.706294 Tz (the ) Tj 1.048951 0 Td 53.030303 Tz (amino ) Tj 62.142857 0 0 62.142857 0 916.695387 Tm 5.181609 0 Td 71.072797 Tz (NO ) Tj 0.917241 0 Td 10.727969 Tz (: ) Tj 0.144828 0 Td 40.229885 Tz (3 ) Tj 0.289655 0 Td 26.819923 Tz (\) ) Tj 0.225287 0 Td 13.409962 Tz (, ) Tj 0.434483 0 Td 43.582375 Tz (then ) Tj 1.367816 0 Td 40.229885 Tz (the ) Tj 1.094253 0 Td 45.350052 Tz (subsequence ) Tj 3.347126 0 Td 44.252874 Tz (of ) Tj 0.804598 0 Td 40.229885 Tz (the ) Tj 1.062069 0 Td 41.123883 Tz (reference ) Tj 2.590805 0 Td 45.258621 Tz (sequence ) Tj 3.411494 0 Td 41.570881 Tz (acid ) Tj 1.255172 0 Td 40.996169 Tz (alanine ) Tj 1.770115 0 Td 10.727969 Tz (. ) Tj 0.370115 0 Td 50.287356 Tz (Thus ) Tj 1.158621 0 Td 24.137931 Tz (, ) Tj 0.450575 0 Td 34.8659 Tz (at ) Tj 0.691954 0 Td 43.984674 Tz (every ) Tj 1.593103 0 Td 40.229885 Tz (position ) Tj 2.188506 0 Td 48.812261 Tz (where ) Tj 1.754023 0 Td 45.59387 Tz (an ) Tj 0.82069 0 Td 40.996169 Tz (alanine ) Tj 1.995402 0 Td 30.842912 Tz (is ) Tj 62.857143 0 0 62.857143 0 875.370142 Tm 5.138636 0 Td 43.240093 Tz (corresponding ) Tj 3.515909 0 Td 37.121212 Tz (to ) Tj 0.588636 0 Td 40.656566 Tz (the ) Tj 0.859091 0 Td 53.030303 Tz (window ) Tj 2.068182 0 Td 45.075758 Tz (of ) Tj 0.620455 0 Td 46.136364 Tz (comparison ) Tj 2.895455 0 Td 47.727273 Tz (must ) Tj 1.304545 0 Td 34.027778 Tz (itself ) Tj 1.304545 0 Td 46.401515 Tz (have ) Tj 1.495455 0 Td 35.795455 Tz (50 ) Tj 0.859091 0 Td 38.594276 Tz (specified ) Tj 2.243182 0 Td 49.05303 Tz (by ) Tj 0.779545 0 Td 39.772727 Tz (a ) Tj 0.429545 0 Td 48.257576 Tz (codon ) Tj 1.463636 0 Td 13.257576 Tz (, ) Tj 0.286364 0 Td 39.772727 Tz (the ) Tj 0.906818 0 Td 48.257576 Tz (codon ) Tj 1.622727 0 Td 45.075758 Tz (can ) Tj 0.970455 0 Td 46.401515 Tz (be ) Tj 0.747727 0 Td 38.257576 Tz (altered ) Tj 1.765909 0 Td 35.795455 Tz (to ) Tj 0.636364 0 Td 46.843434 Tz (any ) Tj 1.034091 0 Td 45.075758 Tz (of ) Tj 0.636364 0 Td 39.772727 Tz (the ) Tj 61.25 0 0 61.25 0 833.993324 Tm 5.273469 0 Td 58.503401 Tz (FHB1 ) Tj 1.697959 0 Td 37.755102 Tz (activity ) Tj 2.040816 0 Td 38.095238 Tz (in ) Tj 0.669388 0 Td 42.993197 Tz (order ) Tj 1.485714 0 Td 36.734694 Tz (to ) Tj 0.702041 0 Td 45.238095 Tz (conclude ) Tj 2.383673 0 Td 38.095238 Tz (that ) Tj 1.126531 0 Td 40.816327 Tz (the ) Tj 0.946939 0 Td 48.979592 Tz (two ) Tj 1.159184 0 Td 44.746788 Tz (sequences ) Tj 3.673469 0 Td 44.374673 Tz (corresponding ) Tj 4.016327 0 Td 47.165533 Tz (codons ) Tj 2.253061 0 Td 43.235072 Tz (described ) Tj 2.857143 0 Td 44.314869 Tz (without ) Tj 2.4 0 Td 38.435374 Tz (altering ) Tj 2.367347 0 Td 40.816327 Tz (the ) Tj 61.052632 0 0 61.052632 0 792.695682 Tm 5.274138 0 Td 49.137931 Tz (meet ) Tj 1.506897 0 Td 40.948276 Tz (the ) Tj 1.064655 0 Td 42.50821 Tz (percent ) Tj 2.12931 0 Td 38.218391 Tz (identity ) Tj 2.178448 0 Td 37.91507 Tz (criterion ) Tj 2.096552 0 Td 19.109195 Tz (. ) Tj 0.442241 0 Td 47.318008 Tz (For ) Tj 1.162931 0 Td 49.137931 Tz (example ) Tj 2.031034 0 Td 27.298851 Tz (, ) Tj 0.507759 0 Td 35.488506 Tz (if ) Tj 0.671552 0 Td 50.047893 Tz (two ) Tj 2.178448 0 Td 48.357964 Tz (encoded ) Tj 2.424138 0 Td 44.422675 Tz (polypeptide ) Tj 2.85 0 Td 27.298851 Tz (. ) Tj 0.638793 0 Td 49.820402 Tz (Such ) Tj 1.605172 0 Td 41.338259 Tz (nucleic ) Tj 2.194828 0 Td 41.630747 Tz (acid ) Tj 1.408621 0 Td 39.856322 Tz (variations ) Tj 2.833621 0 Td 40.038314 Tz (are ) Tj 61.020408 0 0 61.020408 0 752.510876 Tm 5.293311 0 Td 44.915149 Tz (sequences ) Tj 2.605686 0 Td 43.701226 Tz (only ) Tj 1.229097 0 Td 41.516165 Tz (share ) Tj 1.392977 0 Td 71.014493 Tz (X ) Tj 0.573579 0 Td 42.920847 Tz (percent ) Tj 1.950167 0 Td 38.238573 Tz (identity ) Tj 1.999331 0 Td 45.06689 Tz (over ) Tj 1.212709 0 Td 40.9699 Tz (a ) Tj 0.426087 0 Td 39.331104 Tz (short ) Tj 1.327425 0 Td 54.171312 Tz (window ) Tj 3.244816 0 Td 16.38796 Tz (" ) Tj 0.147492 0 Td 39.604236 Tz (silent ) Tj 1.622408 0 Td 42.06243 Tz (variations ) Tj 2.589298 0 Td 16.38796 Tz (, ) Tj 0.147492 0 Td 16.38796 Tz ( ) Tj 0.294983 0 Td 49.710145 Tz (which ) Tj 1.68796 0 Td 40.059457 Tz (are ) Tj 0.934114 0 Td 48.253437 Tz (one ) Tj 1.081605 0 Td 40.9699 Tz (species ) Tj 1.950167 0 Td 45.06689 Tz (of ) Tj 0.688294 0 Td 42.140468 Tz (conservatively ) Tj 60.584416 0 0 60.584416 0 710.629936 Tm 5.314898 0 Td 46.766702 Tz (of ) Tj 0.660236 0 Td 47.591997 Tz (comparison ) Tj 3.037085 0 Td 27.509825 Tz (\( ) Tj 0.181565 0 Td 35.075027 Tz (e.g. ) Tj 0.907824 0 Td 13.754912 Tz (, ) Tj 0.2806 0 Td 48.142194 Tz (20 ) Tj 0.742765 0 Td 44.565916 Tz (contiguous ) Tj 2.85552 0 Td 50.067881 Tz (amino ) Tj 1.683601 0 Td 40.714541 Tz (acids ) Tj 1.270954 0 Td 27.509825 Tz (\) ) Tj 0.214577 0 Td 13.754912 Tz (, ) Tj 0.2806 0 Td 48.600691 Tz (and ) Tj 1.00686 0 Td 38.513755 Tz (that ) Tj 1.089389 0 Td 49.517685 Tz (20 ) Tj 1.865166 0 Td 45.735084 Tz (modified ) Tj 2.525402 0 Td 41.814934 Tz (variations ) Tj 2.459378 0 Td 19.256877 Tz (. ) Tj 0.462165 0 Td 48.417292 Tz (Every ) Tj 1.799143 0 Td 41.657735 Tz (nucleic ) Tj 2.112755 0 Td 42.640229 Tz (acid ) Tj 1.369989 0 Td 46.078957 Tz (sequence ) Tj 2.558414 0 Td 42.640229 Tz (herein ) Tj 64.285714 0 0 64.285714 0 665.587912 Tm 5.024444 0 Td 42 Tz (contiguous ) Tj 2.675556 0 Td 47.185185 Tz (amino ) Tj 1.586667 0 Td 38.37037 Tz (acids ) Tj 1.322222 0 Td 28.518519 Tz (is ) Tj 0.482222 0 Td 41.481481 Tz (not ) Tj 0.902222 0 Td 34.740741 Tz (sufficient ) Tj 2.224444 0 Td 42.12963 Tz (unto ) Tj 1.166667 0 Td 33.703704 Tz (itself ) Tj 1.275556 0 Td 35 Tz (to ) Tj 0.575556 0 Td 41.111111 Tz (possess ) Tj 2.115556 0 Td 33.703704 Tz (55 ) Tj 0.808889 0 Td 47.703704 Tz (which ) Tj 1.633333 0 Td 43.703704 Tz (encodes ) Tj 2.068889 0 Td 38.888889 Tz (a ) Tj 0.435556 0 Td 41.481481 Tz (polypeptide ) Tj 2.955556 0 Td 37.592593 Tz (also ) Tj 1.135556 0 Td 39.465021 Tz (describes ) Tj 2.364444 0 Td 42 Tz (every ) Tj 1.462222 0 Td 39.861111 Tz (possible ) Tj 56.971429 0 0 56.971429 0 626.91624 Tm 5.669509 0 Td 62.897024 Tz (FHB1 ) Tj 1.772818 0 Td 40.590522 Tz (activity ) Tj 2.158977 0 Td 32.179873 Tz (\( ) Tj 0.175527 0 Td 53.828151 Tz (which ) Tj 1.772818 0 Td 54.998328 Tz (would ) Tj 1.807924 0 Td 49.00117 Tz (normally ) Tj 2.527583 0 Td 51.195252 Tz (be ) Tj 0.78987 0 Td 43.881645 Tz (the ) Tj 0.982949 0 Td 46.075727 Tz (case ) Tj 1.140923 0 Td 29.25443 Tz (\) ) Tj 0.228185 0 Td 14.627215 Tz (, ) Tj 0.298395 0 Td 46.807088 Tz (then ) Tj 1.298897 0 Td 43.881645 Tz (the ) Tj 2.158977 0 Td 38.518333 Tz (silent ) Tj 1.597292 0 Td 43.231546 Tz (variation ) Tj 2.545135 0 Td 49.732531 Tz (of ) Tj 0.737212 0 Td 43.881645 Tz (the ) Tj 1.000502 0 Td 44.717486 Tz (nucleic ) Tj 2.123872 0 Td 45.344366 Tz (acid ) Tj 1.12337 0 Td 11.701772 Tz (. ) Tj 0.333501 0 Td 59.484008 Tz (One ) Tj 1.298897 0 Td 49.732531 Tz (of ) Tj 0.772317 0 Td 35.690405 Tz (skill ) Tj 1.298897 0 Td 41.687563 Tz (will ) Tj 1.263791 0 Td 53.828151 Tz (recog ) Tj 63.291925 0 0 63.291925 0 583.677293 Tm 5.087537 0 Td 48.277178 Tz (two ) Tj 1.121786 0 Td 43.303166 Tz (sequences ) Tj 2.591168 0 Td 46.082761 Tz (do ) Tj 0.77419 0 Td 42.13281 Tz (not ) Tj 0.995388 0 Td 35.737651 Tz (satisfy ) Tj 1.722179 0 Td 39.499509 Tz (the ) Tj 0.932188 0 Td 36.866209 Tz (criterion ) Tj 2.211973 0 Td 44.766111 Tz (of ) Tj 0.679392 0 Td 42.13281 Tz (possessing ) Tj 2.749166 0 Td 34.232908 Tz (at ) Tj 1.61158 0 Td 40.81616 Tz (nize ) Tj 1.169185 0 Td 36.207884 Tz (that ) Tj 1.074387 0 Td 44.766111 Tz (each ) Tj 1.263984 0 Td 47.926071 Tz (codon ) Tj 1.62738 0 Td 36.866209 Tz (in ) Tj 0.631992 0 Td 39.499509 Tz (a ) Tj 0.426595 0 Td 40.251881 Tz (nucleic ) Tj 1.911776 0 Td 40.157834 Tz (acid ) Tj 1.184985 0 Td 26.333006 Tz (\( ) Tj 0.173798 0 Td 42.13281 Tz (except ) Tj 1.674779 0 Td 63.199215 Tz (AUG ) Tj 1.263984 0 Td 23.699706 Tz (, ) Tj 0.347596 0 Td 47.926071 Tz (which ) Tj 61.428571 0 0 61.428571 0 543.109974 Tm 5.25814 0 Td 36.356589 Tz (least ) Tj 1.4 0 Td 70.542636 Tz (X ) Tj 0.748837 0 Td 42.635659 Tz (percent ) Tj 2.116279 0 Td 36.28876 Tz (identity ) Tj 1.74186 0 Td 27.131783 Tz (. ) Tj 0.472093 0 Td 41.115086 Tz (Alternatively ) Tj 3.174419 0 Td 27.131783 Tz (, ) Tj 0.472093 0 Td 35.271318 Tz (if ) Tj 0.667442 0 Td 40.697674 Tz (the ) Tj 1.04186 0 Td 54.263566 Tz (window ) Tj 2.27907 0 Td 46.124031 Tz (of ) Tj 1.74186 0 Td 29.844961 Tz (is ) Tj 0.537209 0 Td 39.612403 Tz (ordinarily ) Tj 2.523256 0 Td 40.697674 Tz (the ) Tj 0.895349 0 Td 43.410853 Tz (only ) Tj 1.204651 0 Td 49.379845 Tz (codon ) Tj 1.627907 0 Td 38.888889 Tz (for ) Tj 0.830233 0 Td 46.937984 Tz (Methionine ) Tj 2.816279 0 Td 27.131783 Tz (\) ) Tj 0.34186 0 Td 46.124031 Tz (can ) Tj 0.960465 0 Td 46.124031 Tz (be ) Tj 0.7 0 Td 45.106589 Tz (modified ) Tj 60.252101 0 0 60.252101 0 505.424666 Tm 5.327615 0 Td 48.131102 Tz (comparison ) Tj 3.319386 0 Td 44.258484 Tz (spans ) Tj 1.759275 0 Td 44.258484 Tz (a ) Tj 0.697071 0 Td 43.336433 Tz (longer ) Tj 1.991632 0 Td 46.773171 Tz (subsequence ) Tj 3.51855 0 Td 47.02464 Tz (of ) Tj 0.896234 0 Td 45.364947 Tz (contiguous ) Tj 3.999861 0 Td 37.343096 Tz (to ) Tj 0.630683 0 Td 41.492329 Tz (yield ) Tj 1.394142 0 Td 41.492329 Tz (a ) Tj 0.43152 0 Td 41.261816 Tz (functionally ) Tj 3.13682 0 Td 39.340875 Tz (identical ) Tj 2.27378 0 Td 47.02464 Tz (molecule ) Tj 2.32357 0 Td 11.064621 Tz (. ) Tj 0.21576 0 Td 46.018765 Tz (Accordingly ) Tj 3.020642 0 Td 27.661553 Tz (, ) Tj 0.365132 0 Td 47.02464 Tz (each ) Tj 61.428571 0 0 61.428571 0 457.151439 Tm 5.25814 0 Td 49.379845 Tz (amino ) Tj 1.709302 0 Td 40.697674 Tz (acids ) Tj 1.432558 0 Td 37.984496 Tz (that ) Tj 1.106977 0 Td 42.807924 Tz (possesses ) Tj 2.539535 0 Td 58.333333 Tz (FHB1 ) Tj 1.676744 0 Td 37.645349 Tz (activity ) Tj 2.018605 0 Td 47.48062 Tz (even ) Tj 1.318605 0 Td 44.186047 Tz (without ) Tj 2.067442 0 Td 40.697674 Tz (the ) Tj 1.139535 0 Td 35.271318 Tz (60 ) Tj 0.862791 0 Td 35.723514 Tz (silent ) Tj 1.481395 0 Td 40.094746 Tz (variation ) Tj 2.360465 0 Td 46.124031 Tz (of ) Tj 0.7 0 Td 40.697674 Tz (a ) Tj 0.439535 0 Td 41.472868 Tz (nucleic ) Tj 1.969767 0 Td 41.375969 Tz (acid ) Tj 1.188372 0 Td 49.379845 Tz (which ) Tj 1.693023 0 Td 45.736434 Tz (encodes ) Tj 2.148837 0 Td 40.697674 Tz (a ) Tj 0.52093 0 Td 50 Tz (polypep ) Tj 58.29932 0 0 58.29932 0 418.745974 Tm 5.506068 0 Td 38.593932 Tz (rest ) Tj 1.097783 0 Td 48.599767 Tz (of ) Tj 0.668961 0 Td 42.882147 Tz (the ) Tj 0.96056 0 Td 48.242415 Tz (sequence ) Tj 2.349942 0 Td 20.011669 Tz (, ) Tj 0.291599 0 Td 42.882147 Tz (the ) Tj 0.943407 0 Td 40.023337 Tz (criterion ) Tj 2.315636 0 Td 40.73804 Tz (will ) Tj 1.149242 0 Td 50.029172 Tz (be ) Tj 0.771879 0 Td 49.743291 Tz (found ) Tj 1.629522 0 Td 40.023337 Tz (to ) Tj 0.651809 0 Td 50.029172 Tz (have ) Tj 1.372229 0 Td 50.743874 Tz (been ) Tj 2.52147 0 Td 39.308635 Tz (tide ) Tj 1.2007 0 Td 31.446908 Tz (is ) Tj 0.634656 0 Td 41.095391 Tz (implicit ) Tj 2.212719 0 Td 40.023337 Tz (in ) Tj 0.703267 0 Td 48.599767 Tz (each ) Tj 1.389382 0 Td 45.423311 Tz (described ) Tj 2.692999 0 Td 47.885064 Tz (sequence ) Tj 2.367095 0 Td 20.011669 Tz (. ) Tj 42.857143 0 0 42.857143 0 380.16129 Tm 7.49 0 Td 73.888889 Tz (met ) Tj 1.376667 0 Td 19.444444 Tz (. ) Tj 60 0 0 60 0 377.634855 Tm 22.216667 0 Td 55.555556 Tz (As ) Tj 0.916667 0 Td 38.888889 Tz (to ) Tj 0.733333 0 Td 50.555556 Tz (amino ) Tj 1.783333 0 Td 42.361111 Tz (acid ) Tj 1.266667 0 Td 45.679012 Tz (sequences ) Tj 2.5 0 Td 19.444444 Tz (, ) Tj 0.4 0 Td 48.148148 Tz (one ) Tj 1.116667 0 Td 47.222222 Tz (of ) Tj 0.75 0 Td 33.888889 Tz (skill ) Tj 1.266667 0 Td 39.583333 Tz (will ) Tj 1.2 0 Td 44.444444 Tz (recognize ) Tj 57.293233 0 0 57.293233 0 337.801213 Tm 6.300919 0 Td 53.193351 Tz (Methods ) Tj 2.53084 0 Td 49.453193 Tz (of ) Tj 0.802887 0 Td 47.837076 Tz (alignment ) Tj 2.862467 0 Td 49.453193 Tz (of ) Tj 0.820341 0 Td 47.837076 Tz (sequences ) Tj 2.879921 0 Td 41.69583 Tz (for ) Tj 1.012336 0 Td 50.616798 Tz (comparison ) Tj 3.316273 0 Td 42.6655 Tz (are ) Tj 2.094488 0 Td 40.726159 Tz (that ) Tj 1.361417 0 Td 43.344269 Tz (individual ) Tj 3.037008 0 Td 41.62124 Tz (substitutions ) Tj 3.246457 0 Td 26.181102 Tz (, ) Tj 0.55853 0 Td 42.180665 Tz (in ) Tj 0.872703 0 Td 43.635171 Tz (a ) Tj 0.645801 0 Td 44.050744 Tz (nucleic ) Tj 2.269029 0 Td 45.089676 Tz (acid ) Tj 1.099606 0 Td 14.545057 Tz (, ) Tj 0.506168 0 Td 45.297463 Tz (peptide ) Tj 1.954856 0 Td 14.545057 Tz (, ) Tj 63.831169 0 0 63.831169 0 295.029777 Tm 5.044557 0 Td 43.082401 Tz (well ) Tj 1.127976 0 Td 20.888437 Tz (- ) Tj 0.046999 0 Td 54.309936 Tz (known ) Tj 1.83296 0 Td 36.554764 Tz (in ) Tj 0.626653 0 Td 39.165819 Tz (the ) Tj 0.924313 0 Td 37.425116 Tz (art ) Tj 0.626653 0 Td 15.666328 Tz (. ) Tj 0.328993 0 Td 44.760936 Tz (Optimal ) Tj 2.114954 0 Td 42.937342 Tz (alignment ) Tj 2.537945 0 Td 43.082401 Tz (of ) Tj 0.689318 0 Td 42.937342 Tz (sequences ) Tj 2.553611 0 Td 37.425116 Tz (for ) Tj 1.848627 0 Td 42.014242 Tz (polypeptide ) Tj 2.725941 0 Td 26.110546 Tz (, ) Tj 0.328993 0 Td 40.471346 Tz (or ) Tj 0.610987 0 Td 39.538827 Tz (protein ) Tj 1.817294 0 Td 43.735164 Tz (sequence ) Tj 2.240285 0 Td 48.043405 Tz (which ) Tj 1.582299 0 Td 33.94371 Tz (alters ) Tj 1.394303 0 Td 39.165819 Tz (a ) Tj 0.407325 0 Td 37.860292 Tz (single ) Tj 1.519634 0 Td 46.998983 Tz (amino ) Tj 62.857143 0 0 62.857143 0 251.907203 Tm 5.138636 0 Td 46.136364 Tz (comparison ) Tj 3.022727 0 Td 45.075758 Tz (can ) Tj 1.065909 0 Td 45.075758 Tz (be ) Tj 0.811364 0 Td 44.781145 Tz (conducted ) Tj 2.45 0 Td 23.863636 Tz (, ) Tj 0.397727 0 Td 33.806818 Tz (e.g. ) Tj 0.875 0 Td 13.257576 Tz (, ) Tj 0.365909 0 Td 42.424242 Tz (using ) Tj 1.559091 0 Td 39.772727 Tz (a ) Tj 0.509091 0 Td 44.854798 Tz (computerized ) Tj 3.611364 0 Td 33.143939 Tz (65 ) Tj 0.827273 0 Td 41.098485 Tz (acid ) Tj 1.225 0 Td 39.772727 Tz (or ) Tj 0.715909 0 Td 39.772727 Tz (a ) Tj 0.509091 0 Td 41.363636 Tz (small ) Tj 1.495455 0 Td 42.689394 Tz (percentage ) Tj 2.815909 0 Td 45.075758 Tz (of ) Tj 0.731818 0 Td 48.257576 Tz (amino ) Tj 1.718182 0 Td 39.242424 Tz (acids ) Tj 1.447727 0 Td 37.121212 Tz (in ) Tj 0.668182 0 Td 39.772727 Tz (the ) Tj 0.970455 0 Td 46.969697 Tz (encoded ) Tj 60 0 0 60 0 215.088035 Tm 5.4 0 Td 46.031746 Tz (implementation ) Tj 4.033333 0 Td 50 Tz (of ) Tj 0.666667 0 Td 44.444444 Tz (a ) Tj 0.433333 0 Td 52.083333 Tz (homology ) Tj 2.666667 0 Td 44.444444 Tz (or ) Tj 0.7 0 Td 38.888889 Tz (similarity ) Tj 2.533333 0 Td 45.679012 Tz (alignment ) Tj 2.633333 0 Td 42.222222 Tz (algo- ) Tj 2.55 0 Td 46.527778 Tz (sequence ) Tj 2.5 0 Td 30.555556 Tz (is ) Tj 0.633333 0 Td 41.666667 Tz (a ) Tj 0.5 0 Td 16.666667 Tz ( ) Tj 0.15 0 Td 44.444444 Tz (conservatively ) Tj 3.966667 0 Td 46.527778 Tz (modified ) Tj 2.566667 0 Td 39.68254 Tz (variant ) Tj 1.65 0 Td 33.333333 Tz ( ) Tj 0.466667 0 Td 50 Tz (where ) Tj 1.733333 0 Td 42.592593 Tz (the ) Tj 54.081633 0 0 54.081633 0 172.226721 Tm 5.953962 0 Td 40.062893 Tz (rithm ) Tj 1.460755 0 Td 27.735849 Tz (, ) Tj 0.684151 0 Td 47.767296 Tz (or ) Tj 1.016981 0 Td 57.012579 Tz (by ) Tj 1.146415 0 Td 55.985325 Tz (manual ) Tj 2.514717 0 Td 50.677848 Tz (alignment ) Tj 3.217358 0 Td 55.471698 Tz (and ) Tj 1.442264 0 Td 45.199161 Tz (visual ) Tj 2.126415 0 Td 47.150943 Tz (inspection ) Tj 2.884528 0 Td 12.327044 Tz (. ) Tj 1.534717 0 Td 43.45283 Tz (alteration ) Tj 2.792075 0 Td 42.264151 Tz (results ) Tj 2.015472 0 Td 43.144654 Tz (in ) Tj 0.702642 0 Td 46.226415 Tz (the ) Tj 1.072453 0 Td 44.428721 Tz (substitution ) Tj 3.420755 0 Td 50.849057 Tz (of ) Tj 0.758113 0 Td 53.930818 Tz (an ) Tj 0.850566 0 Td 56.08805 Tz (amino ) Tj 1.923019 0 Td 46.996855 Tz (acid ) Tj 1.331321 0 Td 50.849057 Tz (with ) Tj 1.442264 0 Td 46.226415 Tz (a ) Tj 25.714286 0 0 25.714286 0 1591 Tm 46.861111 0 Td 97.222222 Tz (a ) Tj ET Q endstream endobj 183 0 obj << /Length 1 >> stream q endstream endobj 184 0 obj << /Length 55301 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 60.952381 0 0 60.952381 0 3027.187879 Tm 17.521875 0 Td 84.765625 Tz (US ) Tj 1.44375 0 Td 59.0625 Tz (11,072,799 ) Tj 3.904687 0 Td 71.09375 Tz (B2 ) Tj 50 0 0 50 0 2973 Tm 14.98 0 Td 75 Tz (15 ) Tj 54.285714 0 0 54.285714 0 2971 Tm 31.739474 0 Td 67.54386 Tz (16 ) Tj 62.959184 0 0 62.959184 0 2913.824005 Tm 5.114425 0 Td 43.149649 Tz (chemically ) Tj 2.922528 0 Td 38.573744 Tz (similar ) Tj 1.92188 0 Td 48.179363 Tz (amino ) Tj 1.77893 0 Td 41.031875 Tz (acid ) Tj 1.032415 0 Td 10.588871 Tz (. ) Tj 0.412966 0 Td 43.237889 Tz (Conservative ) Tj 3.446677 0 Td 37.943454 Tz (substitution ) Tj 3.954943 0 Td 42.884927 Tz (Agglutinin ) Tj 2.795462 0 Td 42.355484 Tz (superfamily ) Tj 3.001945 0 Td 46.893571 Tz (domains ) Tj 2.191896 0 Td 38.82586 Tz (are ) Tj 0.889465 0 Td 44.340897 Tz (provided ) Tj 2.334846 0 Td 39.443544 Tz (separately ) Tj 2.573096 0 Td 38.384657 Tz (as ) Tj 60.37594 0 0 60.37594 0 2872.274572 Tm 5.33325 0 Td 39.566902 Tz (tables ) Tj 1.689415 0 Td 44.167704 Tz (providing ) Tj 2.666625 0 Td 41.177183 Tz (functionally ) Tj 3.246326 0 Td 40.224159 Tz (similar ) Tj 1.937858 0 Td 50.240764 Tz (amino ) Tj 1.788792 0 Td 40.855127 Tz (acids ) Tj 1.507223 0 Td 40.487062 Tz (are ) Tj 0.97721 0 Td 43.477584 Tz (well ) Tj 2.35193 0 Td 62.570915 Tz (SEQ ) Tj 1.325031 0 Td 51.068908 Tz (ID ) Tj 0.795019 0 Td 67.171717 Tz (NOS ) Tj 1.291905 0 Td 11.041926 Tz (: ) Tj 0.149066 0 Td 44.167704 Tz (7 ) Tj 0.463761 0 Td 49.688667 Tz (and ) Tj 1.093151 0 Td 31.745538 Tz (8. ) Tj 0.596264 0 Td 52.449149 Tz (The ) Tj 1.076588 0 Td 44.995849 Tz (Agglutinin ) Tj 2.898506 0 Td 44.167704 Tz (superfamily ) Tj 3.09726 0 Td 42.442403 Tz (includes ) Tj 46.285714 0 0 46.285714 0 2835.13242 Tm 6.95679 0 Td 73.45679 Tz (known ) Tj 2.484568 0 Td 52.211934 Tz (in ) Tj 0.885802 0 Td 54.012346 Tz (the ) Tj 1.274691 0 Td 44.410151 Tz (art ) Tj 0.885802 0 Td 21.604938 Tz (. ) Tj 61.428571 0 0 61.428571 0 2825.084724 Tm 21.097674 0 Td 40.358527 Tz (proteins ) Tj 2.230233 0 Td 37.306202 Tz (like ) Tj 1.123256 0 Td 49.922481 Tz (Amaranthus ) Tj 3.272093 0 Td 45.445736 Tz (caudatus ) Tj 2.45814 0 Td 40.155039 Tz (agglutinin ) Tj 2.44186 0 Td 27.131783 Tz (, ) Tj 0.423256 0 Td 49.922481 Tz (which ) Tj 1.75814 0 Td 29.844961 Tz (is ) Tj 0.651163 0 Td 40.697674 Tz (a ) Tj 60.952381 0 0 60.952381 0 2790.411924 Tm 5.90625 0 Td 51.041667 Tz (The ) Tj 1.164844 0 Td 43.75 Tz (following ) Tj 2.625 0 Td 37.369792 Tz (six ) Tj 0.91875 0 Td 45.117188 Tz (groups ) Tj 1.886719 0 Td 46.484375 Tz (each ) Tj 1.345312 0 Td 42.578125 Tz (contain ) Tj 2.017969 0 Td 49.765625 Tz (amino ) Tj 1.755469 0 Td 40.46875 Tz (acids ) Tj 1.460156 0 Td 38.28125 Tz (that ) Tj 62.857143 0 0 62.857143 0 2783.41623 Tm 20.65 0 Td 35.353535 Tz (lectin ) Tj 1.336364 0 Td 10.606061 Tz (. ) Tj 0.413636 0 Td 47.064394 Tz (Although ) Tj 2.609091 0 Td 40.656566 Tz (the ) Tj 1.081818 0 Td 39.242424 Tz (biological ) Tj 2.736364 0 Td 41.098485 Tz (function ) Tj 2.322727 0 Td 47.727273 Tz (of ) Tj 0.827273 0 Td 48.787879 Tz (Amaranthus ) Tj 54.285714 0 0 54.285714 0 2749 Tm 5.95 0 Td 45.02924 Tz (are ) Tj 1.068421 0 Td 48.099415 Tz (conservative ) Tj 3.739474 0 Td 43.690958 Tz (substitutions ) Tj 3.684211 0 Td 45.02924 Tz (for ) Tj 1.05 0 Td 53.216374 Tz (one ) Tj 1.215789 0 Td 49.561404 Tz (another ) Tj 2.063158 0 Td 21.491228 Tz (: ) Tj 65.714286 0 0 65.714286 0 2738.341398 Tm 19.036957 0 Td 27.898551 Tz (5 ) Tj 0.7 0 Td 42.481884 Tz (caudatus ) Tj 2.343478 0 Td 38.297101 Tz (agglutinin ) Tj 2.602174 0 Td 27.898551 Tz (is ) Tj 0.654348 0 Td 49.637681 Tz (unknown ) Tj 2.084783 0 Td 22.826087 Tz (, ) Tj 0.471739 0 Td 38.043478 Tz (the ) Tj 0.98913 0 Td 38.405797 Tz (protein ) Tj 1.902174 0 Td 40.57971 Tz (has ) Tj 1.065217 0 Td 38.043478 Tz (a ) Tj 0.532609 0 Td 41.847826 Tz (high ) Tj 58.571429 0 0 58.571429 0 2703 Tm 6.214634 0 Td 28.455285 Tz (1 ) Tj 0.256098 0 Td 28.455285 Tz (\) ) Tj 0.37561 0 Td 47.96748 Tz (Alanine ) Tj 2.270732 0 Td 31.300813 Tz (\( ) Tj 0.341463 0 Td 28.455285 Tz (A ) Tj 0.358537 0 Td 28.455285 Tz (\) ) Tj 0.102439 0 Td 28.455285 Tz (, ) Tj 0.460976 0 Td 44.105691 Tz (Serine ) Tj 1.843902 0 Td 28.455285 Tz (\( ) Tj 0.204878 0 Td 48.373984 Tz (S ) Tj 0.341463 0 Td 28.455285 Tz (\) ) Tj 0.221951 0 Td 14.227642 Tz (, ) Tj 0.358537 0 Td 48.057814 Tz (Threonine ) Tj 2.85122 0 Td 28.455285 Tz (\( ) Tj 0.187805 0 Td 59.756098 Tz (T ) Tj 0.392683 0 Td 28.455285 Tz (\) ) Tj 0.256098 0 Td 14.227642 Tz (; ) Tj 60 0 0 60 0 2700.646489 Tm 21.6 0 Td 45.238095 Tz (binding ) Tj 2.066667 0 Td 37.878788 Tz (specificity ) Tj 2.666667 0 Td 40.740741 Tz (for ) Tj 0.866667 0 Td 40.740741 Tz (the ) Tj 0.866667 0 Td 50.462963 Tz (methyl ) Tj 1.783333 0 Td 27.777778 Tz (- ) Tj 0.216667 0 Td 43.209877 Tz (glycoside ) Tj 2.466667 0 Td 47.222222 Tz (of ) Tj 0.633333 0 Td 42.592593 Tz (the ) Tj 0.9 0 Td 50 Tz (T ) Tj 0.416667 0 Td 27.777778 Tz (- ) Tj 0.2 0 Td 38.492063 Tz (antigen ) Tj 1.7 0 Td 27.777778 Tz (, ) Tj 57.653061 0 0 57.653061 0 2664.796443 Tm 6.244248 0 Td 46.253687 Tz (2 ) Tj 0.312212 0 Td 28.908555 Tz (\) ) Tj 0.381593 0 Td 45.169617 Tz (Aspartic ) Tj 2.428319 0 Td 44.80826 Tz (acid ) Tj 1.31823 0 Td 28.908555 Tz (\( ) Tj 0.208142 0 Td 72.271386 Tz (D ) Tj 0.468319 0 Td 28.908555 Tz (\) ) Tj 0.225487 0 Td 14.454277 Tz (, ) Tj 0.364248 0 Td 49.144543 Tz (Glutamic ) Tj 2.63646 0 Td 44.085546 Tz (acid ) Tj 1.300885 0 Td 28.908555 Tz (\( ) Tj 0.208142 0 Td 60.707965 Tz (E ) Tj 0.398938 0 Td 28.908555 Tz (\) ) Tj 0.242832 0 Td 14.454277 Tz (; ) Tj 52.857143 0 0 52.857143 0 2652 Tm 24.518919 0 Td 58.018018 Tz (which ) Tj 1.910811 0 Td 34.684685 Tz (is ) Tj 0.624324 0 Td 48.348348 Tz (linked ) Tj 1.891892 0 Td 44.144144 Tz (to ) Tj 0.756757 0 Td 45.195195 Tz (serine ) Tj 1.816216 0 Td 48.873874 Tz (or ) Tj 0.718919 0 Td 49.399399 Tz (threonine ) Tj 2.837838 0 Td 47.691441 Tz (residues ) Tj 2.497297 0 Td 52.027027 Tz (of ) Tj 0.737838 0 Td 40.990991 Tz (cell ) Tj 1.191892 0 Td 47.747748 Tz (surface ) Tj 60.47619 0 0 60.47619 0 2621.85553 Tm 5.952756 0 Td 41.338583 Tz (3 ) Tj 0.297638 0 Td 27.559055 Tz (\) ) Tj 0.36378 0 Td 46.850394 Tz (Asparagine ) Tj 3.059055 0 Td 33.070866 Tz (\( ) Tj 0.281102 0 Td 27.559055 Tz (N ) Tj 0.413386 0 Td 27.559055 Tz (\) ) Tj 0.115748 0 Td 27.559055 Tz (, ) Tj 0.39685 0 Td 47.769029 Tz (Glutamine ) Tj 2.827559 0 Td 27.559055 Tz (\( ) Tj 0.198425 0 Td 68.897638 Tz (O ) Tj 0.446457 0 Td 27.559055 Tz (\) ) Tj 0.231496 0 Td 13.779528 Tz (; ) Tj 61.428571 0 0 61.428571 0 2610.100386 Tm 21.113953 0 Td 42.367323 Tz (glycoproteins ) Tj 3.255814 0 Td 27.131783 Tz (. ) Tj 0.537209 0 Td 49.922481 Tz (Amaranthus ) Tj 3.386047 0 Td 45.445736 Tz (caudatus ) Tj 2.572093 0 Td 40.968992 Tz (agglutinin ) Tj 2.848837 0 Td 29.844961 Tz (is ) Tj 0.797674 0 Td 66.020672 Tz (com ) Tj 54.285714 0 0 54.285714 0 2587.19774 Tm 6.631579 0 Td 55.263158 Tz (4 ) Tj 0.405263 0 Td 24.561404 Tz (\) ) Tj 0.368421 0 Td 50.657895 Tz (Arginine ) Tj 2.689474 0 Td 30.701754 Tz (\( ) Tj 0.221053 0 Td 67.54386 Tz (R ) Tj 0.442105 0 Td 30.701754 Tz (\) ) Tj 0.257895 0 Td 18.421053 Tz (, ) Tj 0.405263 0 Td 50.146199 Tz (Lysine ) Tj 2.063158 0 Td 30.701754 Tz (\( ) Tj 0.221053 0 Td 73.684211 Tz (K ) Tj 0.478947 0 Td 30.701754 Tz (\) ) Tj 0.257895 0 Td 18.421053 Tz (; ) Tj 61.428571 0 0 61.428571 0 2563.678967 Tm 21.097674 0 Td 41.602067 Tz (prised ) Tj 1.676744 0 Td 46.124031 Tz (of ) Tj 0.7 0 Td 40.697674 Tz (a ) Tj 0.423256 0 Td 51.851852 Tz (homodimer ) Tj 2.783721 0 Td 24.418605 Tz (, ) Tj 0.34186 0 Td 44.767442 Tz (with ) Tj 1.269767 0 Td 46.124031 Tz (each ) Tj 1.286047 0 Td 52.153316 Tz (homodimer ) Tj 2.995349 0 Td 40.697674 Tz (consisting ) Tj 2.653488 0 Td 46.124031 Tz (of ) Tj 57.142857 0 0 57.142857 0 2538 Tm 6.335 0 Td 40.833333 Tz (5 ) Tj 0.2975 0 Td 29.166667 Tz (\) ) Tj 0.5075 0 Td 44.333333 Tz (Isoleucine ) Tj 3.01 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 29.166667 Tz (I ) Tj 0.2275 0 Td 29.166667 Tz (\) ) Tj 0.2275 0 Td 14.583333 Tz (, ) Tj 0.4375 0 Td 49.583333 Tz (Leucine ) Tj 2.415 0 Td 29.166667 Tz (\( ) Tj 0.21 0 Td 61.25 Tz (L ) Tj 0.4025 0 Td 29.166667 Tz (\) ) Tj 0.2275 0 Td 14.583333 Tz (, ) Tj 0.4375 0 Td 49.875 Tz (Methionine ) Tj 3.325 0 Td 29.166667 Tz (\( ) Tj 0.21 0 Td 93.333333 Tz (M ) Tj 0.5775 0 Td 29.166667 Tz (\) ) Tj 0.2275 0 Td 14.583333 Tz (, ) Tj 0.42 0 Td 46.180556 Tz (Valine ) Tj 2.1175 0 Td 36.458333 Tz (10 ) Tj 46.666667 0 0 46.666667 0 2526.42042 Tm 27.75 0 Td 64.285714 Tz (two ) Tj 1.478571 0 Td 51.785714 Tz (beta ) Tj 1.414286 0 Td 28.571429 Tz (- ) Tj 0.278571 0 Td 43.367347 Tz (trefoil ) Tj 2.142857 0 Td 63.265306 Tz (domains ) Tj 2.764286 0 Td 14.285714 Tz (. ) Tj 56.285714 0 0 56.285714 0 2498.766355 Tm 5.720812 0 Td 44.416244 Tz (\( ) Tj 0.373096 0 Td 35.532995 Tz (V ) Tj 0.337563 0 Td 35.532995 Tz (\) ) Tj 0.159898 0 Td 35.532995 Tz (; ) Tj 0.426396 0 Td 55.273548 Tz (and ) Tj 57.142857 0 0 57.142857 0 2459.939219 Tm 6.335 0 Td 43.75 Tz (6 ) Tj 0.2975 0 Td 29.166667 Tz (\) ) Tj 0.4375 0 Td 47.339744 Tz (Phenylalanine ) Tj 3.955 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 52.5 Tz (F ) Tj 0.3675 0 Td 29.166667 Tz (\) ) Tj 0.2275 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 47.03125 Tz (Tyrosine ) Tj 2.52 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 78.75 Tz (Y ) Tj 0.49 0 Td 29.166667 Tz (\) ) Tj 0.2275 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 50.458333 Tz (Tryptophan ) Tj 3.2725 0 Td 29.166667 Tz (\( ) Tj 0.21 0 Td 99.166667 Tz (W ) Tj 0.6125 0 Td 29.166667 Tz (\) ) Tj 0.245 0 Td 11.666667 Tz (. ) Tj 58.571429 0 0 58.571429 0 2474 Tm 22.758537 0 Td 50.406504 Tz (Another ) Tj 2.492683 0 Td 47.425474 Tz (conserved ) Tj 2.953659 0 Td 42.398374 Tz (functional ) Tj 2.953659 0 Td 53.116531 Tz (domain ) Tj 1.929268 0 Td 14.227642 Tz (, ) Tj 0.512195 0 Td 29.878049 Tz (i.e. ) Tj 0.802439 0 Td 14.227642 Tz (, ) Tj 0.495122 0 Td 42.682927 Tz (the ) Tj 1.160976 0 Td 67.344173 Tz (ETX ) Tj 1.229268 0 Td 28.455285 Tz (/ ) Tj 60 0 0 60 0 2416.090041 Tm 5.983333 0 Td 63.888889 Tz (An ) Tj 1.05 0 Td 41.111111 Tz (indication ) Tj 2.716667 0 Td 38.888889 Tz (that ) Tj 1.183333 0 Td 50.925926 Tz (two ) Tj 1.2 0 Td 42.063492 Tz (nucleic ) Tj 2.066667 0 Td 42.361111 Tz (acid ) Tj 1.3 0 Td 45.679012 Tz (sequences ) Tj 2.766667 0 Td 43.055556 Tz (or ) Tj 0.716667 0 Td 56.944444 Tz (poly ) Tj 57.619048 0 0 57.619048 0 2434.309201 Tm 22.492562 0 Td 71.590909 Tz (MTX2 ) Tj 2.082645 0 Td 46.280992 Tz (superfamily ) Tj 3.401653 0 Td 49.655647 Tz (domain ) Tj 1.909091 0 Td 26.033058 Tz (, ) Tj 0.503306 0 Td 35.867769 Tz (falls ) Tj 1.405785 0 Td 46.280992 Tz (within ) Tj 1.961157 0 Td 43.38843 Tz (the ) Tj 1.110744 0 Td 62.672176 Tz (ETX ) Tj 1.301653 0 Td 23.140496 Tz (/ ) Tj 57.142857 0 0 57.142857 0 2434 Tm 36.4525 0 Td 78.75 Tz (MTX2 ) Tj 62.857143 0 0 62.857143 0 2375.600512 Tm 5.122727 0 Td 41.098485 Tz (peptides ) Tj 2.227273 0 Td 40.656566 Tz (are ) Tj 0.986364 0 Td 37.937063 Tz (substantially ) Tj 3.245455 0 Td 37.415825 Tz (identical ) Tj 2.290909 0 Td 31.818182 Tz (is ) Tj 0.636364 0 Td 35.795455 Tz (that ) Tj 1.145455 0 Td 38.888889 Tz (the ) Tj 0.954545 0 Td 42.424242 Tz (polypeptide ) Tj 60.714286 0 0 60.714286 0 2391.635324 Tm 21.362353 0 Td 43.921569 Tz (superfamily ) Tj 2.832941 0 Td 27.45098 Tz (, ) Tj 0.411765 0 Td 48.496732 Tz (and ) Tj 1.103529 0 Td 30.196078 Tz (is ) Tj 0.592941 0 Td 42.352941 Tz (present ) Tj 1.992941 0 Td 35.686275 Tz (at ) Tj 0.658824 0 Td 49.960784 Tz (amino ) Tj 1.745882 0 Td 41.176471 Tz (acid ) Tj 1.218824 0 Td 41.960784 Tz (residue ) Tj 1.976471 0 Td 40.87146 Tz (positions ) Tj 73.154762 0 0 73.154762 0 2334.673405 Tm 4.401627 0 Td 40.358015 Tz (encoded ) Tj 1.872742 0 Td 43.287225 Tz (by ) Tj 0.615134 0 Td 38.730675 Tz (the ) Tj 0.888527 0 Td 26.42799 Tz (first ) Tj 0.970545 0 Td 35.150529 Tz (nucleic ) Tj 1.654028 0 Td 35.313263 Tz (acid ) Tj 1.038893 0 Td 26.200163 Tz (is ) Tj 0.519447 0 Td 38.88256 Tz (immunologically ) Tj 3.677136 0 Td 34.62978 Tz (cross ) Tj 1.366965 0 Td 29.617575 Tz (15 ) Tj 0.820179 0 Td 39.381611 Tz (351-428 ) Tj 1.790724 0 Td 22.78275 Tz (in ) Tj 0.423759 0 Td 57.716301 Tz (SEQ ) Tj 1.216599 0 Td 43.287225 Tz (ID ) Tj 0.683483 0 Td 61.513426 Tz (NO ) Tj 0.77917 0 Td 11.391375 Tz (: ) Tj 0.109357 0 Td 36.4524 Tz (3 ) Tj 0.287063 0 Td 11.391375 Tz (. ) Tj 0.246054 0 Td 43.287225 Tz (The ) Tj 0.943206 0 Td 41.92026 Tz (amino ) Tj 1.435313 0 Td 35.313263 Tz (acid ) Tj 1.038893 0 Td 38.445891 Tz (sequence ) Tj 2.009439 0 Td 38.730675 Tz (of ) Tj 0.560456 0 Td 34.93355 Tz (the ) Tj 61.785714 0 0 61.785714 0 2290.779172 Tm 5.211561 0 Td 39.788054 Tz (reactive ) Tj 2.136416 0 Td 45.183044 Tz (with ) Tj 1.294798 0 Td 41.361593 Tz (the ) Tj 0.987283 0 Td 40.732177 Tz (antibodies ) Tj 2.686705 0 Td 40.462428 Tz (raised ) Tj 1.699422 0 Td 40.077071 Tz (against ) Tj 1.909827 0 Td 40.462428 Tz (the ) Tj 0.971098 0 Td 43.159923 Tz (polypeptide ) Tj 60.952381 0 0 60.952381 0 2307.039092 Tm 21.295312 0 Td 55.598958 Tz (ETX ) Tj 1.246875 0 Td 21.875 Tz (/ ) Tj 0 0 Td 72.460938 Tz (MTX2 ) Tj 2.001562 0 Td 43.75 Tz (superfamily ) Tj 3.15 0 Td 50.130208 Tz (domain ) Tj 2.067187 0 Td 30.078125 Tz (is ) Tj 0.623437 0 Td 45.117188 Tz (provided ) Tj 2.428125 0 Td 40.46875 Tz (separately ) Tj 2.690625 0 Td 41.015625 Tz (as ) Tj 58.809524 0 0 58.809524 0 2249.084724 Tm 5.492308 0 Td 49.797571 Tz (encoded ) Tj 2.295547 0 Td 52.42915 Tz (by ) Tj 0.850202 0 Td 42.510121 Tz (the ) Tj 1.003239 0 Td 48.178138 Tz (second ) Tj 1.938462 0 Td 42.91498 Tz (nucleic ) Tj 2.040486 0 Td 43.927126 Tz (acid ) Tj 1.105263 0 Td 11.336032 Tz (. ) Tj 0.306073 0 Td 55.263158 Tz (Thus ) Tj 1.241296 0 Td 25.506073 Tz (, ) Tj 0.391093 0 Td 42.510121 Tz (a ) Tj 0.459109 0 Td 45.34413 Tz (polypeptide ) Tj 3.230769 0 Td 31.174089 Tz (is ) Tj 64.285714 0 0 64.285714 0 2255.836709 Tm 20.191111 0 Td 58.765432 Tz (SEQ ) Tj 1.244444 0 Td 47.962963 Tz (ID ) Tj 0.746667 0 Td 68.703704 Tz (NO ) Tj 0.886667 0 Td 10.37037 Tz (: ) Tj 0.155556 0 Td 38.888889 Tz (9 ) Tj 0.295556 0 Td 10.37037 Tz (. ) Tj 0.264444 0 Td 49.259259 Tz (The ) Tj 1.057778 0 Td 61.358025 Tz (ETX ) Tj 1.12 0 Td 25.925926 Tz (/ ) Tj 0.186667 0 Td 64.166667 Tz (MTX2 ) Tj 1.757778 0 Td 41.481481 Tz (superfamily ) Tj 2.908889 0 Td 39.861111 Tz (includes ) Tj 2.193333 0 Td 47.314815 Tz (Epsi ) Tj 60 0 0 60 0 2209.435424 Tm 5.366667 0 Td 40.123457 Tz (typically ) Tj 2.366667 0 Td 40.17094 Tz (substantially ) Tj 3.333333 0 Td 38.888889 Tz (identical ) Tj 2.3 0 Td 36.111111 Tz (to ) Tj 0.633333 0 Td 44.444444 Tz (a ) Tj 0.466667 0 Td 47.222222 Tz (second ) Tj 1.9 0 Td 43.686869 Tz (polypeptide ) Tj 2.866667 0 Td 27.777778 Tz (, ) Tj 0.4 0 Td 38.888889 Tz (for ) Tj 61.428571 0 0 61.428571 0 2215.24 Tm 21.113953 0 Td 42.50646 Tz (lon ) Tj 0.927907 0 Td 41.782946 Tz (toxin ) Tj 1.432558 0 Td 32.55814 Tz (\( ) Tj 0.17907 0 Td 59.689922 Tz (ETX ) Tj 1.22093 0 Td 27.131783 Tz (\) ) Tj 0.113953 0 Td 27.131783 Tz (, ) Tj 0.35814 0 Td 49.922481 Tz (which ) Tj 1.660465 0 Td 31.20155 Tz (is ) Tj 0.553488 0 Td 47.141473 Tz (produced ) Tj 2.425581 0 Td 50.193798 Tz (by ) Tj 0.797674 0 Td 43.1642 Tz (Clostridium ) Tj 3.093023 0 Td 43.410853 Tz (perfrin ) Tj 57.763975 0 0 57.763975 0 2170.232342 Tm 5.59172 0 Td 49.462366 Tz (example ) Tj 2.146667 0 Td 28.853047 Tz (, ) Tj 0.346237 0 Td 52.512545 Tz (where ) Tj 1.731183 0 Td 43.27957 Tz (the ) Tj 0.952151 0 Td 51.935484 Tz (two ) Tj 1.125269 0 Td 44.361559 Tz (peptides ) Tj 2.319785 0 Td 38.470729 Tz (differ ) Tj 1.558065 0 Td 46.164875 Tz (only ) Tj 1.281075 0 Td 53.378136 Tz (by ) Tj 0.813656 0 Td 45.203106 Tz (conservative ) Tj 4.535699 0 Td 49.771505 Tz (gens ) Tj 1.350323 0 Td 46.164875 Tz (type ) Tj 1.281075 0 Td 63.476703 Tz (B ) Tj 0.588602 0 Td 50.973716 Tz (and ) Tj 1.090645 0 Td 72.132616 Tz (D ) Tj 0.623226 0 Td 39.982079 Tz (strains ) Tj 1.661935 0 Td 25.967742 Tz (, ) Tj 0.328925 0 Td 50.973716 Tz (and ) Tj 1.090645 0 Td 47.496554 Tz (Mosquitocidal ) Tj 3.877849 0 Td 44.433692 Tz (toxin ) Tj 1.506129 0 Td 28.853047 Tz (\( ) Tj 0.207742 0 Td 71.41129 Tz (MTX2 ) Tj 1.765806 0 Td 28.853047 Tz (\) ) Tj 62.857143 0 0 62.857143 0 2124.908407 Tm 5.154545 0 Td 38.956876 Tz (substitutions ) Tj 2.959091 0 Td 26.515152 Tz (. ) Tj 0.525 0 Td 46.590909 Tz (Another ) Tj 2.290909 0 Td 40.568182 Tz (indication ) Tj 2.815909 0 Td 37.121212 Tz (that ) Tj 1.304545 0 Td 50.378788 Tz (two ) Tj 1.256818 0 Td 40.530303 Tz (nucleic ) Tj 2.131818 0 Td 41.098485 Tz (acid ) Tj 1.352273 0 Td 35.795455 Tz (20 ) Tj 0.827273 0 Td 48.787879 Tz (which ) Tj 1.638636 0 Td 29.166667 Tz (is ) Tj 0.540909 0 Td 46.070076 Tz (produced ) Tj 2.370455 0 Td 49.05303 Tz (by ) Tj 0.747727 0 Td 40.767045 Tz (Bacillus ) Tj 2.131818 0 Td 42.954545 Tz (sphaericus ) Tj 2.529545 0 Td 26.515152 Tz (. ) Tj 0.381818 0 Td 62.752525 Tz (ETX ) Tj 1.320455 0 Td 46.843434 Tz (and ) Tj 1.018182 0 Td 65.625 Tz (MTX2 ) Tj 62.030075 0 0 62.030075 0 2083.533037 Tm 5.207152 0 Td 44.184063 Tz (sequences ) Tj 2.692242 0 Td 39.407407 Tz (are ) Tj 1.015636 0 Td 38.44289 Tz (substantially ) Tj 3.288727 0 Td 37.914703 Tz (identical ) Tj 2.337576 0 Td 30.89899 Tz (is ) Tj 0.644848 0 Td 37.616162 Tz (that ) Tj 1.160727 0 Td 41.198653 Tz (the ) Tj 0.999515 0 Td 49.259259 Tz (two ) Tj 1.128485 0 Td 51.722222 Tz (mol- ) Tj 2.418182 0 Td 39.407407 Tz (are ) Tj 0.854424 0 Td 44.333333 Tz (pore ) Tj 1.225212 0 Td 45.676768 Tz (forming ) Tj 2.063515 0 Td 40.30303 Tz (toxins ) Tj 1.612121 0 Td 36.944444 Tz (that ) Tj 1.047879 0 Td 39.855219 Tz (attach ) Tj 1.563758 0 Td 36.272727 Tz (to ) Tj 0.596485 0 Td 40.30303 Tz (the ) Tj 0.870545 0 Td 47.468013 Tz (plasma ) Tj 1.853939 0 Td 51.050505 Tz (membranes ) Tj 63.642857 0 0 63.642857 0 2040.137476 Tm 5.075196 0 Td 39.718169 Tz (ecules ) Tj 1.681257 0 Td 39.281706 Tz (or ) Tj 0.675645 0 Td 36.139169 Tz (their ) Tj 1.28844 0 Td 46.899976 Tz (complements ) Tj 3.331089 0 Td 41.02756 Tz (hybridize ) Tj 2.419753 0 Td 36.662926 Tz (to ) Tj 0.691358 0 Td 43.864572 Tz (each ) Tj 1.272727 0 Td 40.329218 Tz (other ) Tj 1.398429 0 Td 45.043023 Tz (under ) Tj 2.545455 0 Td 44.519267 Tz (of ) Tj 0.612795 0 Td 39.281706 Tz (a ) Tj 0.377104 0 Td 40.591096 Tz (host ) Tj 1.131313 0 Td 46.26512 Tz (and ) Tj 0.974186 0 Td 44.519267 Tz (produce ) Tj 2.011223 0 Td 39.281706 Tz (toxins ) Tj 1.571268 0 Td 36.662926 Tz (that ) Tj 1.037037 0 Td 39.936401 Tz (lead ) Tj 1.084175 0 Td 36.662926 Tz (to ) Tj 0.612795 0 Td 37.78526 Tz (altered ) Tj 1.712682 0 Td 41.02756 Tz (permeability ) Tj 57.346939 0 0 57.346939 0 2001.025362 Tm 5.632384 0 Td 41.656781 Tz (stringent ) Tj 2.493594 0 Td 44.466192 Tz (conditions ) Tj 2.720285 0 Td 14.531435 Tz (, ) Tj 0.366192 0 Td 42.141163 Tz (as ) Tj 0.76726 0 Td 45.854752 Tz (described ) Tj 2.702847 0 Td 52.313167 Tz (below ) Tj 1.60427 0 Td 11.625148 Tz (. ) Tj 58.571429 0 0 58.571429 0 1999.387755 Tm 22.143902 0 Td 50.271003 Tz (and ) Tj 1.126829 0 Td 44.579946 Tz (ion ) Tj 0.870732 0 Td 25.609756 Tz (- ) Tj 0.256098 0 Td 37.466125 Tz (efflux ) Tj 1.34878 0 Td 25.609756 Tz (, ) Tj 0.37561 0 Td 41.102078 Tz (resulting ) Tj 2.458537 0 Td 41.260163 Tz (in ) Tj 0.717073 0 Td 36.280488 Tz (cell ) Tj 1.126829 0 Td 43.252033 Tz (death ) Tj 1.365854 0 Td 19.918699 Tz (. ) Tj 62.857143 0 0 62.857143 0 1959.481177 Tm 5.727273 0 Td 51.262626 Tz (The ) Tj 1.177273 0 Td 43.308081 Tz (phrase ) Tj 1.845455 0 Td 26.515152 Tz (" ) Tj 0.302273 0 Td 37.362259 Tz (selectively ) Tj 2.784091 0 Td 26.515152 Tz (\( ) Tj 0.190909 0 Td 39.772727 Tz (or ) Tj 0.763636 0 Td 36.900253 Tz (specifically ) Tj 2.704545 0 Td 26.515152 Tz (\) ) Tj 0.445455 0 Td 40.833333 Tz (hybridizes ) Tj 2.768182 0 Td 31.818182 Tz (to ) Tj 0.572727 0 Td 21.212121 Tz (" ) Tj 1.940909 0 Td 48.257576 Tz (Based ) Tj 1.654545 0 Td 49.05303 Tz (on ) Tj 0.795455 0 Td 39.109848 Tz (analysis ) Tj 2.1 0 Td 45.075758 Tz (of ) Tj 0.684091 0 Td 39.772727 Tz (the ) Tj 0.922727 0 Td 48.257576 Tz (amino ) Tj 1.686364 0 Td 41.098485 Tz (acid ) Tj 1.209091 0 Td 44.412879 Tz (sequence ) Tj 2.354545 0 Td 45.075758 Tz (of ) Tj 0.684091 0 Td 57.007576 Tz (FHB1 ) Tj 1.479545 0 Td 13.257576 Tz (, ) Tj 62.857143 0 0 62.857143 0 1915.976353 Tm 5.122727 0 Td 37.121212 Tz (refers ) Tj 1.590909 0 Td 35.795455 Tz (to ) Tj 0.7 0 Td 39.772727 Tz (the ) Tj 0.970455 0 Td 41.666667 Tz (binding ) Tj 1.765909 0 Td 26.515152 Tz (, ) Tj 0.445455 0 Td 43.897306 Tz (duplexing ) Tj 2.354545 0 Td 26.515152 Tz (, ) Tj 0.413636 0 Td 41.098485 Tz (or ) Tj 0.715909 0 Td 41.460055 Tz (hybridizing ) Tj 2.990909 0 Td 45.075758 Tz (of ) Tj 0.731818 0 Td 39.772727 Tz (a ) Tj 0.493182 0 Td 45.738636 Tz (mol- ) Tj 1.495455 0 Td 34.469697 Tz (25 ) Tj 0.827273 0 Td 39.772727 Tz (the ) Tj 0.843182 0 Td 50.378788 Tz (mechanism ) Tj 2.847727 0 Td 47.727273 Tz (by ) Tj 0.715909 0 Td 48.787879 Tz (which ) Tj 1.575 0 Td 39.772727 Tz (the ) Tj 0.875 0 Td 57.007576 Tz (FHB1 ) Tj 1.559091 0 Td 40.151515 Tz (protein ) Tj 1.829545 0 Td 45.407197 Tz (improves ) Tj 2.338636 0 Td 40.530303 Tz (disease ) Tj 60 0 0 60 0 1876.309272 Tm 5.383333 0 Td 42.777778 Tz (ecule ) Tj 1.533333 0 Td 45.138889 Tz (only ) Tj 1.316667 0 Td 38.888889 Tz (to ) Tj 0.733333 0 Td 41.666667 Tz (a ) Tj 0.483333 0 Td 39.722222 Tz (particular ) Tj 2.6 0 Td 43.333333 Tz (nucleotide ) Tj 2.85 0 Td 46.875 Tz (sequence ) Tj 2.483333 0 Td 47.777778 Tz (under ) Tj 1.683333 0 Td 36.111111 Tz (strin- ) Tj 2.533333 0 Td 41.111111 Tz (resistance ) Tj 2.666667 0 Td 27.777778 Tz (is ) Tj 0.533333 0 Td 41.975309 Tz (predicted ) Tj 2.433333 0 Td 38.888889 Tz (to ) Tj 0.633333 0 Td 44.444444 Tz (involve ) Tj 2.033333 0 Td 40.740741 Tz (the ) Tj 0.9 0 Td 43.888889 Tz (Agglutinin ) Tj 2.8 0 Td 44.949495 Tz (superfamily ) Tj 59.327731 0 0 59.327731 0 1834.192112 Tm 5.444334 0 Td 44.245751 Tz (gent ) Tj 1.247309 0 Td 43.219293 Tz (hybridization ) Tj 3.53966 0 Td 43.262512 Tz (conditions ) Tj 2.781161 0 Td 57.589707 Tz (when ) Tj 1.550708 0 Td 38.627243 Tz (that ) Tj 1.146176 0 Td 47.055005 Tz (sequence ) Tj 2.460907 0 Td 32.306421 Tz (is ) Tj 0.573088 0 Td 43.342776 Tz (present ) Tj 3.118272 0 Td 51.971199 Tz (domain ) Tj 2.157507 0 Td 44.948064 Tz (recognizing ) Tj 3.286827 0 Td 49.630154 Tz (and ) Tj 1.196742 0 Td 41.37265 Tz (identifying ) Tj 3.033994 0 Td 42.13881 Tz (the ) Tj 1.078754 0 Td 35.817989 Tz (cell ) Tj 1.196742 0 Td 42.540132 Tz (surface ) Tj 2.090085 0 Td 47.757318 Tz (of ) Tj 0.825921 0 Td 42.13881 Tz (a ) Tj 62.678571 0 0 62.678571 0 1791.610828 Tm 5.153276 0 Td 37.226971 Tz (in ) Tj 0.638177 0 Td 39.88604 Tz (a ) Tj 0.446724 0 Td 48.243115 Tz (complex ) Tj 2.217664 0 Td 44.064577 Tz (mixture ) Tj 2.074074 0 Td 26.590693 Tz (\( ) Tj 0.175499 0 Td 33.903134 Tz (e.g. ) Tj 0.877493 0 Td 13.295347 Tz (, ) Tj 0.303134 0 Td 34.567901 Tz (total ) Tj 1.244444 0 Td 37.226971 Tz (cellular ) Tj 1.978348 0 Td 41.215575 Tz (or ) Tj 0.670085 0 Td 37.226971 Tz (library ) Tj 1.77094 0 Td 70.908515 Tz (DNA ) Tj 1.435897 0 Td 41.215575 Tz (or ) Tj 1.675214 0 Td 44.539411 Tz (pathogen ) Tj 2.153846 0 Td 26.590693 Tz (, ) Tj 0.39886 0 Td 39.354226 Tz (especially ) Tj 2.584615 0 Td 41.215575 Tz (fungal ) Tj 1.707123 0 Td 43.54226 Tz (pathogen ) Tj 2.137892 0 Td 26.590693 Tz (, ) Tj 0.414815 0 Td 47.863248 Tz (and ) Tj 1.052991 0 Td 39.88604 Tz (the ) Tj 0.941311 0 Td 54.954099 Tz (ETX ) Tj 1.196581 0 Td 18.613485 Tz (/ ) Tj 0 0 Td 71.130104 Tz (MTX2 ) Tj 65.037594 0 0 65.037594 0 1749.412459 Tm 4.966358 0 Td 64.919717 Tz (RNA ) Tj 1.291561 0 Td 25.626204 Tz (\) ) Tj 0.061503 0 Td 25.626204 Tz (. ) Tj 0.568902 0 Td 47.835581 Tz (The ) Tj 1.245434 0 Td 41.42903 Tz (phrase ) Tj 1.90659 0 Td 25.626204 Tz (" ) Tj 0.292139 0 Td 36.161422 Tz (stringent ) Tj 2.33711 0 Td 39.42493 Tz (hybridization ) Tj 3.459538 0 Td 39.720617 Tz (conditions ) Tj 2.475491 0 Td 25.626204 Tz ( ) Tj 1.353064 0 Td 41.001927 Tz (superfamily ) Tj 2.952139 0 Td 47.835581 Tz (domain ) Tj 1.952717 0 Td 43.198459 Tz (forming ) Tj 2.075723 0 Td 38.439306 Tz (a ) Tj 0.445896 0 Td 42.283237 Tz (pore ) Tj 1.260809 0 Td 37.157996 Tz (in ) Tj 0.661156 0 Td 38.439306 Tz (the ) Tj 0.922543 0 Td 50.291426 Tz (membrane ) Tj 2.644624 0 Td 35.876686 Tz (that ) Tj 61.428571 0 0 61.428571 0 1707.542875 Tm 5.24186 0 Td 37.984496 Tz (refers ) Tj 1.530233 0 Td 36.627907 Tz (to ) Tj 0.618605 0 Td 41.782946 Tz (conditions ) Tj 2.669767 0 Td 46.666667 Tz (under ) Tj 1.530233 0 Td 49.379845 Tz (which ) Tj 1.644186 0 Td 40.697674 Tz (a ) Tj 0.390698 0 Td 45.581395 Tz (probe ) Tj 1.530233 0 Td 37.984496 Tz (will ) Tj 1.074419 0 Td 42.50646 Tz (hybridize ) Tj 2.44186 0 Td 37.984496 Tz (to ) Tj 0.634884 0 Td 29.844961 Tz (its ) Tj 0.944186 0 Td 36.627907 Tz (30 ) Tj 0.846512 0 Td 34.186047 Tz (kills ) Tj 1.286047 0 Td 40.697674 Tz (the ) Tj 0.993023 0 Td 44.089147 Tz (pathogen ) Tj 2.181395 0 Td 27.131783 Tz (. ) Tj 0.455814 0 Td 41.472868 Tz (Protein ) Tj 2.018605 0 Td 40.204369 Tz (subcellular ) Tj 2.897674 0 Td 39.341085 Tz (localization ) Tj 3.14186 0 Td 46.576227 Tz (predic ) Tj 58.888889 0 0 58.888889 0 1667.813686 Tm 5.450943 0 Td 39.622642 Tz (target ) Tj 1.867925 0 Td 46.569468 Tz (subsequence ) Tj 3.124528 0 Td 28.301887 Tz (, ) Tj 0.611321 0 Td 40.880503 Tz (typically ) Tj 2.649057 0 Td 36.792453 Tz (in ) Tj 0.849057 0 Td 45.283019 Tz (a ) Tj 0.679245 0 Td 51.752022 Tz (complex ) Tj 2.615094 0 Td 46.091644 Tz (mixture ) Tj 2.343396 0 Td 48.113208 Tz (of ) Tj 1.816981 0 Td 41.037736 Tz (tion ) Tj 1.290566 0 Td 44.575472 Tz (software ) Tj 2.445283 0 Td 67.115903 Tz (LOCTREE ) Tj 3.124528 0 Td 42.45283 Tz (3 ) Tj 0.577358 0 Td 41.037736 Tz (predicts ) Tj 2.275472 0 Td 39.622642 Tz (that ) Tj 1.239623 0 Td 60.849057 Tz (FHB1 ) Tj 1.8 0 Td 43.261456 Tz (protein ) Tj 2.088679 0 Td 32.54717 Tz (is ) Tj 59.214286 0 0 59.214286 0 1623.481203 Tm 5.437877 0 Td 43.023723 Tz (nucleic ) Tj 1.992762 0 Td 43.62686 Tz (acid ) Tj 1.08082 0 Td 14.073181 Tz (, ) Tj 0.270205 0 Td 45.034178 Tz (but ) Tj 0.962606 0 Td 37.997587 Tz (to ) Tj 0.641737 0 Td 50.66345 Tz (no ) Tj 0.810615 0 Td 42.782469 Tz (other ) Tj 1.46924 0 Td 46.285127 Tz (sequences ) Tj 2.55006 0 Td 19.702453 Tz (. ) Tj 0.320869 0 Td 42.219542 Tz (Stringent ) Tj 2.448733 0 Td 43.345396 Tz (conditions ) Tj 3.934861 0 Td 42.571371 Tz (secreted ) Tj 2.279855 0 Td 42.621632 Tz (outside ) Tj 2.043426 0 Td 37.153197 Tz (cells ) Tj 1.384801 0 Td 38.279051 Tz (after ) Tj 1.367913 0 Td 44.189787 Tz (production ) Tj 2.718938 0 Td 28.146361 Tz (, ) Tj 0.405308 0 Td 51.226377 Tz (which ) Tj 1.773221 0 Td 32.368315 Tz (is ) Tj 0.641737 0 Td 41.938078 Tz (consistent ) Tj 57.983193 0 0 57.983193 0 1583.611928 Tm 5.553333 0 Td 42.15781 Tz (are ) Tj 1.103768 0 Td 48.146135 Tz (sequence ) Tj 2.414493 0 Td 28.743961 Tz (- ) Tj 0.137971 0 Td 48.864734 Tz (dependent ) Tj 2.94913 0 Td 51.73913 Tz (and ) Tj 1.207246 0 Td 40.960145 Tz (will ) Tj 1.310725 0 Td 48.864734 Tz (be ) Tj 0.914058 0 Td 39.922169 Tz (different ) Tj 2.483478 0 Td 38.804348 Tz (in ) Tj 0.793333 0 Td 39.922169 Tz (different ) Tj 3.483768 0 Td 48.146135 Tz (with ) Tj 1.362464 0 Td 43.115942 Tz (the ) Tj 1.00029 0 Td 49.583333 Tz (proposed ) Tj 2.586957 0 Td 58.925121 Tz (mode ) Tj 1.655652 0 Td 48.864734 Tz (of ) Tj 0.758841 0 Td 43.595008 Tz (action ) Tj 1.603913 0 Td 11.497585 Tz (. ) Tj 60.571429 0 0 60.571429 0 1541.388368 Tm 5.316038 0 Td 44.660135 Tz (circumstances ) Tj 3.516509 0 Td 19.261006 Tz (. ) Tj 0.412736 0 Td 49.528302 Tz (Longer ) Tj 2.04717 0 Td 45.859539 Tz (sequences ) Tj 2.740566 0 Td 43.413697 Tz (hybridize ) Tj 2.608491 0 Td 38.522013 Tz (specifically ) Tj 3.070755 0 Td 35.77044 Tz (at ) Tj 2.311321 0 Td 52.279874 Tz (The ) Tj 1.106132 0 Td 43.107966 Tz (invention ) Tj 2.492925 0 Td 39.209906 Tz (also ) Tj 1.122642 0 Td 43.681211 Tz (provides ) Tj 2.294811 0 Td 38.522013 Tz (in ) Tj 0.627358 0 Td 39.701258 Tz (certain ) Tj 1.832547 0 Td 49.778445 Tz (embodiments ) Tj 3.466981 0 Td 42.374214 Tz (other ) Tj 56.666667 0 0 56.666667 0 1505.080268 Tm 5.682353 0 Td 47.058824 Tz (higher ) Tj 1.905882 0 Td 47.54902 Tz (temperatures ) Tj 3.370588 0 Td 26.470588 Tz (. ) Tj 60 0 0 60 0 1499.129032 Tm 20.733333 0 Td 36.111111 Tz (35 ) Tj 0.866667 0 Td 41.319444 Tz (proteins ) Tj 2.133333 0 Td 38.888889 Tz (that ) Tj 1.083333 0 Td 40.740741 Tz (are ) Tj 0.866667 0 Td 44.444444 Tz (not ) Tj 0.95 0 Td 38.888889 Tz (identical ) Tj 2.266667 0 Td 37.5 Tz (to ) Tj 0.616667 0 Td 49.074074 Tz (any ) Tj 1.033333 0 Td 47.222222 Tz (of ) Tj 0.633333 0 Td 41.666667 Tz (the ) Tj 0.9 0 Td 41.319444 Tz (proteins ) Tj 2.15 0 Td 38.888889 Tz (identified ) Tj 59.565217 0 0 59.565217 0 1456.267653 Tm 6.043796 0 Td 45.5683 Tz (Nucleic ) Tj 2.19927 0 Td 41.411192 Tz (acids ) Tj 1.510949 0 Td 38.473236 Tz (that ) Tj 1.191971 0 Td 47.56691 Tz (do ) Tj 0.839416 0 Td 43.836172 Tz (not ) Tj 1.040876 0 Td 43.525277 Tz (hybridize ) Tj 2.60219 0 Td 37.773723 Tz (to ) Tj 0.738686 0 Td 47.56691 Tz (each ) Tj 1.376642 0 Td 43.090024 Tz (other ) Tj 1.510949 0 Td 48.126521 Tz (under ) Tj 2.719708 0 Td 49.245742 Tz (above ) Tj 1.510949 0 Td 13.990268 Tz (, ) Tj 0.352555 0 Td 34.975669 Tz (e.g. ) Tj 0.923358 0 Td 13.990268 Tz (, ) Tj 0.318978 0 Td 42.770247 Tz (protein ) Tj 1.99781 0 Td 40.222019 Tz (variants ) Tj 1.99781 0 Td 25.182482 Tz (, ) Tj 0.352555 0 Td 43.836172 Tz (but ) Tj 1.007299 0 Td 38.473236 Tz (that ) Tj 1.175182 0 Td 42.530414 Tz (share ) Tj 1.527737 0 Td 53.163017 Tz (some ) Tj 1.510949 0 Td 45.701541 Tz (degree ) Tj 1.880292 0 Td 47.56691 Tz (of ) Tj 62.255639 0 0 62.255639 0 1416.357097 Tm 5.204348 0 Td 38.372249 Tz (stringent ) Tj 2.377295 0 Td 40.960145 Tz (conditions ) Tj 2.778865 0 Td 39.264627 Tz (are ) Tj 1.028019 0 Td 28.377617 Tz (still ) Tj 1.188647 0 Td 38.509538 Tz (substantially ) Tj 3.308937 0 Td 37.479871 Tz (identical ) Tj 2.345169 0 Td 34.802738 Tz (if ) Tj 0.642512 0 Td 40.157005 Tz (the ) Tj 1.943599 0 Td 50.530898 Tz (homology ) Tj 2.586111 0 Td 44.172705 Tz (with ) Tj 1.220773 0 Td 46.40365 Tz (one ) Tj 1.011957 0 Td 41.495572 Tz (or ) Tj 0.626449 0 Td 50.865539 Tz (more ) Tj 1.397464 0 Td 45.511272 Tz (of ) Tj 0.626449 0 Td 40.157005 Tz (the ) Tj 0.883454 0 Td 39.822363 Tz (proteins ) Tj 2.088164 0 Td 37.747585 Tz (identified ) Tj 2.40942 0 Td 47.117552 Tz (above ) Tj 1.461715 0 Td 13.385668 Tz (, ) Tj 62.063492 0 0 62.063492 0 1377.604077 Tm 5.188235 0 Td 42.519182 Tz (polypeptides ) Tj 3.367519 0 Td 37.595908 Tz (that ) Tj 1.192327 0 Td 42.966752 Tz (they ) Tj 1.353453 0 Td 46.547315 Tz (encode ) Tj 1.981841 0 Td 40.28133 Tz (are ) Tj 1.047315 0 Td 38.422192 Tz (substantially ) Tj 3.319182 0 Td 38.789429 Tz (identical ) Tj 2.094629 0 Td 18.797954 Tz (. ) Tj 1.33734 0 Td 41.086957 Tz (preferably ) Tj 2.61023 0 Td 40.28133 Tz (a ) Tj 0.386701 0 Td 37.595908 Tz (relatively ) Tj 2.400767 0 Td 44.980818 Tz (high ) Tj 1.20844 0 Td 43.861893 Tz (degree ) Tj 1.740153 0 Td 44.309463 Tz (of ) Tj 0.612276 0 Td 51.358696 Tz (homology ) Tj 2.368542 0 Td 26.85422 Tz (. ) Tj 0.322251 0 Td 41.624041 Tz (In ) Tj 0.612276 0 Td 40.87809 Tz (preferred ) Tj 60.186335 0 0 60.186335 0 1333.356008 Tm 5.350052 0 Td 44.306846 Tz (This ) Tj 1.31259 0 Td 43.383786 Tz (occurs ) Tj 1.644892 0 Td 16.615067 Tz (, ) Tj 0.332301 0 Td 39.691549 Tz (for ) Tj 0.913829 0 Td 49.449604 Tz (example ) Tj 2.126729 0 Td 13.845889 Tz (, ) Tj 0.315686 0 Td 55.383557 Tz (when ) Tj 1.561816 0 Td 35.999312 Tz (a ) Tj 0.481837 0 Td 49.152907 Tz (copy ) Tj 1.395666 0 Td 47.076023 Tz (of ) Tj 0.714448 0 Td 41.537668 Tz (a ) Tj 0.465222 0 Td 41.933265 Tz (nucleic ) Tj 2.010423 0 Td 42.922257 Tz (acid ) Tj 1.229515 0 Td 31.845545 Tz (is ) Tj 1.678122 0 Td 50.348688 Tz (embodiments ) Tj 3.306398 0 Td 24.922601 Tz (, ) Tj 0.348916 0 Td 41.537668 Tz (a ) Tj 0.398762 0 Td 50.952872 Tz (homologous ) Tj 3.223323 0 Td 41.933265 Tz (protein ) Tj 1.927348 0 Td 45.691434 Tz (of ) Tj 0.647988 0 Td 41.537668 Tz (the ) Tj 0.913829 0 Td 43.383786 Tz (invention ) Tj 2.475645 0 Td 39.164087 Tz (retains ) Tj 65.714286 0 0 65.714286 0 1288.614458 Tm 4.915217 0 Td 38.768116 Tz (created ) Tj 1.780435 0 Td 40.57971 Tz (using ) Tj 1.384783 0 Td 38.043478 Tz (the ) Tj 0.836957 0 Td 55.072464 Tz (maximum ) Tj 2.480435 0 Td 46.15942 Tz (codon ) Tj 1.536957 0 Td 42.862319 Tz (degeneracy ) Tj 2.73913 0 Td 40.297907 Tz (permitted ) Tj 2.328261 0 Td 46.92029 Tz (by ) Tj 0.913043 0 Td 35.507246 Tz (40 ) Tj 0.836957 0 Td 48.188406 Tz (some ) Tj 1.202174 0 Td 12.681159 Tz (, ) Tj 0.273913 0 Td 41.847826 Tz (or ) Tj 0.456522 0 Td 15.217391 Tz (, ) Tj 0.273913 0 Td 48.188406 Tz (more ) Tj 1.308696 0 Td 38.297101 Tz (preferably ) Tj 2.267391 0 Td 25.362319 Tz (, ) Tj 0.365217 0 Td 36.287625 Tz (substantially ) Tj 3.013043 0 Td 29.589372 Tz (all ) Tj 0.715217 0 Td 43.115942 Tz (of ) Tj 0.608696 0 Td 38.043478 Tz (the ) Tj 0.852174 0 Td 38.297101 Tz (functional ) Tj 60 0 0 60 0 1248.325049 Tm 5.366667 0 Td 41.666667 Tz (the ) Tj 1 0 Td 41.666667 Tz (genetic ) Tj 2 0 Td 47.916667 Tz (code ) Tj 1.166667 0 Td 19.444444 Tz (. ) Tj 0.383333 0 Td 43.055556 Tz (In ) Tj 0.75 0 Td 46.527778 Tz (such ) Tj 1.333333 0 Td 42.777778 Tz (cases ) Tj 1.333333 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 42.592593 Tz (the ) Tj 0.983333 0 Td 42.063492 Tz (nucleic ) Tj 2.033333 0 Td 41.111111 Tz (acids ) Tj 1.466667 0 Td 40.432099 Tz (typically ) Tj 3.466667 0 Td 39.074074 Tz (characteristics ) Tj 3.816667 0 Td 45.833333 Tz (of ) Tj 0.75 0 Td 42.361111 Tz (wild ) Tj 1.15 0 Td 27.777778 Tz (- ) Tj 0.216667 0 Td 41.666667 Tz (type ) Tj 1.283333 0 Td 59.722222 Tz (FHB1 ) Tj 1.75 0 Td 39.285714 Tz (protein ) Tj 1.716667 0 Td 27.777778 Tz (, ) Tj 0.466667 0 Td 43.055556 Tz (or ) Tj 0.766667 0 Td 41.666667 Tz (a ) Tj 0.516667 0 Td 41.666667 Tz (functional ) Tj 60 0 0 60 0 1213.207054 Tm 5.366667 0 Td 43.518519 Tz (hybridize ) Tj 2.616667 0 Td 47.777778 Tz (under ) Tj 1.683333 0 Td 46.388889 Tz (moderately ) Tj 3.083333 0 Td 39.814815 Tz (stringent ) Tj 2.416667 0 Td 42.735043 Tz (hybridization ) Tj 3.7 0 Td 40.740741 Tz (condi- ) Tj 2.766667 0 Td 45.833333 Tz (fragment ) Tj 2.566667 0 Td 47.222222 Tz (of ) Tj 0.866667 0 Td 40.972222 Tz (wild ) Tj 1.15 0 Td 27.777778 Tz (- ) Tj 0.2 0 Td 42.361111 Tz (type ) Tj 1.416667 0 Td 58.333333 Tz (FHB1 ) Tj 1.833333 0 Td 38.888889 Tz (protein ) Tj 1.733333 0 Td 27.777778 Tz (, ) Tj 0.566667 0 Td 42.592593 Tz (including ) Tj 2.666667 0 Td 42.592593 Tz (but ) Tj 1.133333 0 Td 44.444444 Tz (not ) Tj 44.285714 0 0 44.285714 0 1173 Tm 7.270968 0 Td 53.44086 Tz (tions ) Tj 61.428571 0 0 61.428571 0 1165.934492 Tm 21.113953 0 Td 40.697674 Tz (limited ) Tj 2.018605 0 Td 36.627907 Tz (to ) Tj 0.781395 0 Td 40.697674 Tz (the ) Tj 1.074419 0 Td 40.968992 Tz (agglutinin ) Tj 2.8 0 Td 43.410853 Tz (superfamily ) Tj 3.206977 0 Td 50.193798 Tz (domain ) Tj 2.132558 0 Td 47.028424 Tz (and ) Tj 0.944186 0 Td 18.992248 Tz (/ ) Tj 0.146512 0 Td 37.984496 Tz (or ) Tj 0.748837 0 Td 41.602067 Tz (the ) Tj 61.764706 0 0 61.764706 0 1124.552532 Tm 5.844762 0 Td 40.47619 Tz (In ) Tj 0.66381 0 Td 38.93424 Tz (certain ) Tj 1.813333 0 Td 41.075838 Tz (preferred ) Tj 2.39619 0 Td 49.062049 Tz (embodiments ) Tj 3.221905 0 Td 24.285714 Tz (, ) Tj 0.35619 0 Td 40.47619 Tz (the ) Tj 0.922857 0 Td 42.275132 Tz (invention ) Tj 2.444762 0 Td 43.174603 Tz (provides ) Tj 3.335238 0 Td 63.862434 Tz (ETX ) Tj 1.165714 0 Td 26.984127 Tz (/ ) Tj 0.178095 0 Td 66.785714 Tz (MTX2 ) Tj 1.959048 0 Td 43.174603 Tz (superfamily ) Tj 3.173333 0 Td 49.920635 Tz (domain ) Tj 1.845714 0 Td 10.793651 Tz (. ) Tj 0.437143 0 Td 49.246032 Tz (Such ) Tj 1.473333 0 Td 49.380952 Tz (homologous ) Tj 3.270476 0 Td 55.767196 Tz (pro ) Tj 60 0 0 60 0 1084.02836 Tm 5.383333 0 Td 48.611111 Tz (an ) Tj 0.733333 0 Td 59.722222 Tz (FHB1 ) Tj 1.65 0 Td 42.063492 Tz (protein ) Tj 1.9 0 Td 46.759259 Tz (having ) Tj 1.833333 0 Td 41.666667 Tz (the ) Tj 0.916667 0 Td 50.555556 Tz (amino ) Tj 1.7 0 Td 43.055556 Tz (acid ) Tj 1.2 0 Td 46.527778 Tz (sequence ) Tj 2.4 0 Td 47.222222 Tz (of ) Tj 0.683333 0 Td 62.037037 Tz (SEQ ) Tj 1.3 0 Td 51.388889 Tz (ID ) Tj 1.016667 0 Td 37.5 Tz (45 ) Tj 0.883333 0 Td 38.333333 Tz (teins ) Tj 1.35 0 Td 42.283951 Tz (generally ) Tj 2.483333 0 Td 42.222222 Tz (share ) Tj 1.45 0 Td 36.111111 Tz (at ) Tj 0.6 0 Td 37.222222 Tz (least ) Tj 1.316667 0 Td 44.444444 Tz (65 ) Tj 0.6 0 Td 80.555556 Tz (% ) Tj 0.683333 0 Td 46.875 Tz (sequence ) Tj 2.416667 0 Td 39.236111 Tz (identity ) Tj 2.05 0 Td 46.527778 Tz (with ) Tj 1.25 0 Td 42.592593 Tz (the ) Tj 60.230415 0 0 60.230415 0 1040.855541 Tm 5.346136 0 Td 73.329508 Tz (NO ) Tj 0.946366 0 Td 11.068605 Tz (: ) Tj 0.149426 0 Td 41.507269 Tz (3 ) Tj 0.464881 0 Td 27.671512 Tz (\( ) Tj 0.182632 0 Td 16.602907 Tz (" ) Tj 0.149426 0 Td 36.664754 Tz (wild ) Tj 0.91316 0 Td 49.808722 Tz (- ) Tj 0.332058 0 Td 51.192298 Tz (type ) Tj 1.394644 0 Td 59.493752 Tz (FHB1 ) Tj 1.643688 0 Td 40.716654 Tz (protein ) Tj 1.82632 0 Td 27.671512 Tz ( ) Tj 0.265647 0 Td 27.671512 Tz (\) ) Tj 0.11622 0 Td 27.671512 Tz (. ) Tj 0.298852 0 Td 55.343025 Tz (As ) Tj 0.830145 0 Td 47.733359 Tz (used ) Tj 1.278424 0 Td 39.662501 Tz (herein ) Tj 1.560673 0 Td 24.904361 Tz (, ) Tj 0.282249 0 Td 41.507269 Tz (the ) Tj 0.896557 0 Td 45.38128 Tz (terms ) Tj 2.656465 0 Td 42.737114 Tz (disclosed ) Tj 2.623259 0 Td 46.426649 Tz (sequences ) Tj 2.507039 0 Td 19.370059 Tz (, ) Tj 0.431676 0 Td 42.337414 Tz (preferably ) Tj 2.872303 0 Td 35.972966 Tz (at ) Tj 0.747131 0 Td 37.079827 Tz (least ) Tj 1.444453 0 Td 45.657995 Tz (75 ) Tj 0.614308 0 Td 80.247386 Tz (% ) Tj 0.531293 0 Td 13.835756 Tz (, ) Tj 0.431676 0 Td 42.890844 Tz (or ) Tj 0.830145 0 Td 34.58939 Tz (at ) Tj 0.747131 0 Td 37.079827 Tz (least ) Tj 58.768473 0 0 58.768473 0 1002.402806 Tm 5.496144 0 Td 28.359877 Tz (" ) Tj 0.340319 0 Td 39.703828 Tz (protein ) Tj 1.83772 0 Td 28.359877 Tz ( ) Tj 0.646605 0 Td 51.047779 Tz (and ) Tj 1.37829 0 Td 31.195865 Tz ( ) Tj 0.306287 0 Td 45.891437 Tz (polypeptide ) Tj 3.079883 0 Td 28.359877 Tz ( ) Tj 0.646605 0 Td 41.594486 Tz (are ) Tj 1.225147 0 Td 48.920788 Tz (used ) Tj 1.633529 0 Td 44.430474 Tz (interchangeably ) Tj 3.964711 0 Td 28.359877 Tz (, ) Tj 1.531433 0 Td 46.793797 Tz (85 ) Tj 0.612573 0 Td 82.243643 Tz (% ) Tj 0.561526 0 Td 14.179939 Tz (, ) Tj 0.272255 0 Td 42.539816 Tz (or ) Tj 0.663621 0 Td 35.449846 Tz (at ) Tj 0.595557 0 Td 38.002235 Tz (least ) Tj 1.310226 0 Td 46.793797 Tz (95 ) Tj 0.629589 0 Td 82.243643 Tz (% ) Tj 0.54451 0 Td 14.179939 Tz (, ) Tj 0.272255 0 Td 50.102449 Tz (and ) Tj 1.054987 0 Td 49.629785 Tz (even ) Tj 1.310226 0 Td 54.592763 Tz (more ) Tj 1.446354 0 Td 43.390612 Tz (preferably ) Tj 2.773596 0 Td 35.449846 Tz (at ) Tj 0.595557 0 Td 38.002235 Tz (least ) Tj 1.310226 0 Td 48.211791 Tz (99 ) Tj 0.629589 0 Td 82.243643 Tz (% ) Tj 0.561526 0 Td 11.343951 Tz (. ) Tj 62.040816 0 0 62.040816 0 955.019733 Tm 5.190132 0 Td 41.19152 Tz (unless ) Tj 1.821382 0 Td 42.982456 Tz (otherwise ) Tj 2.643421 0 Td 40.893031 Tz (indicated ) Tj 2.498355 0 Td 49.698465 Tz (by ) Tj 0.91875 0 Td 42.214912 Tz (context ) Tj 1.805263 0 Td 16.118421 Tz (. ) Tj 0.419079 0 Td 41.639254 Tz (In ) Tj 0.822039 0 Td 51.041667 Tz (some ) Tj 1.579605 0 Td 47.971491 Tz (embodi- ) Tj 3.207566 0 Td 40.296053 Tz (In ) Tj 0.644737 0 Td 37.878289 Tz (particular ) Tj 2.240461 0 Td 26.864035 Tz (, ) Tj 0.338487 0 Td 48.355263 Tz (minor ) Tj 1.627961 0 Td 38.642881 Tz (substitutions ) Tj 2.981908 0 Td 24.177632 Tz (, ) Tj 0.354605 0 Td 39.997563 Tz (deletions ) Tj 2.127632 0 Td 24.177632 Tz (, ) Tj 0.354605 0 Td 47.459795 Tz (and ) Tj 1.015461 0 Td 40.296053 Tz (the ) Tj 0.902632 0 Td 36.266447 Tz (like ) Tj 1.047697 0 Td 45.66886 Tz (can ) Tj 62.173913 0 0 62.173913 0 915.783086 Tm 5.179021 0 Td 48.251748 Tz (ments ) Tj 1.447552 0 Td 21.445221 Tz (, ) Tj 0.305594 0 Td 41.103341 Tz (the ) Tj 0.916783 0 Td 40.592741 Tz (protein ) Tj 1.881818 0 Td 44.677545 Tz (comprises ) Tj 2.38042 0 Td 26.806527 Tz (, ) Tj 0.386014 0 Td 38.869464 Tz (consists ) Tj 2.074825 0 Td 48.251748 Tz (of ) Tj 0.45035 0 Td 24.125874 Tz (, ) Tj 0.36993 0 Td 41.550117 Tz (or ) Tj 0.675524 0 Td 38.869464 Tz (consists ) Tj 2.139161 0 Td 41.103341 Tz (essen- ) Tj 2.637762 0 Td 46.911422 Tz (be ) Tj 0.82028 0 Td 42.622378 Tz (introduced ) Tj 2.814685 0 Td 33.508159 Tz (at ) Tj 0.675524 0 Td 46.464646 Tz (one ) Tj 1.093706 0 Td 41.550117 Tz (or ) Tj 0.723776 0 Td 51.602564 Tz (more ) Tj 1.495804 0 Td 48.787879 Tz (amino ) Tj 1.737063 0 Td 41.550117 Tz (acid ) Tj 1.238462 0 Td 39.61409 Tz (positions ) Tj 2.428671 0 Td 37.529138 Tz (in ) Tj 0.675524 0 Td 41.103341 Tz (the ) Tj 60 0 0 60 0 875.186472 Tm 5.366667 0 Td 35.185185 Tz (tially ) Tj 1.416667 0 Td 54.166667 Tz (of ) Tj 0.7 0 Td 37.962963 Tz (the ) Tj 0.833333 0 Td 34.722222 Tz (full ) Tj 1 0 Td 50.555556 Tz (amino ) Tj 1.683333 0 Td 43.055556 Tz (acid ) Tj 1.183333 0 Td 46.527778 Tz (sequence ) Tj 2.383333 0 Td 47.222222 Tz (of ) Tj 0.666667 0 Td 62.962963 Tz (SEQ ) Tj 1.283333 0 Td 52.777778 Tz (ID ) Tj 0.766667 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.15 0 Td 41.666667 Tz (3 ) Tj 0.316667 0 Td 13.888889 Tz (, ) Tj 0.25 0 Td 46.111111 Tz (while ) Tj 1.783333 0 Td 37.5 Tz (50 ) Tj 0.883333 0 Td 42.901235 Tz (disclosed ) Tj 2.483333 0 Td 45.679012 Tz (sequences ) Tj 2.65 0 Td 45.238095 Tz (without ) Tj 2.066667 0 Td 43.209877 Tz (departing ) Tj 2.5 0 Td 50 Tz (from ) Tj 1.35 0 Td 41.666667 Tz (the ) Tj 0.933333 0 Td 46.111111 Tz (scope ) Tj 1.55 0 Td 47.222222 Tz (of ) Tj 0.65 0 Td 42.592593 Tz (the ) Tj 62.539683 0 0 62.539683 0 833.789574 Tm 5.164721 0 Td 37.309645 Tz (in ) Tj 0.655584 0 Td 41.040609 Tz (other ) Tj 1.423096 0 Td 48.211814 Tz (embodiments ) Tj 3.389848 0 Td 40.862944 Tz (the ) Tj 0.927411 0 Td 40.35533 Tz (protein ) Tj 1.902792 0 Td 44.120135 Tz (comprises ) Tj 2.638325 0 Td 50.634518 Tz (some ) Tj 1.471066 0 Td 40.973985 Tz (contigu- ) Tj 3.16599 0 Td 40.566836 Tz (invention ) Tj 2.222589 0 Td 23.984772 Tz (, ) Tj 0.415736 0 Td 39.974619 Tz (so ) Tj 0.735533 0 Td 43.305838 Tz (long ) Tj 1.279188 0 Td 37.309645 Tz (as ) Tj 0.687563 0 Td 39.974619 Tz (the ) Tj 0.959391 0 Td 38.832487 Tz (altered ) Tj 1.870812 0 Td 44.638325 Tz (sequence ) Tj 2.366497 0 Td 42.639594 Tz (maintains ) Tj 2.654315 0 Td 49.968274 Tz (func ) Tj 59.52381 0 0 59.52381 0 793.414386 Tm 5.4264 0 Td 46.666667 Tz (ous ) Tj 1.1088 0 Td 46.9 Tz (fragment ) Tj 2.52 0 Td 43.4 Tz (or ) Tj 0.756 0 Td 45.733333 Tz (fragments ) Tj 2.7552 0 Td 47.6 Tz (of ) Tj 0.756 0 Td 42 Tz (the ) Tj 1.0248 0 Td 50.96 Tz (amino ) Tj 1.8144 0 Td 43.4 Tz (acid ) Tj 1.3104 0 Td 46.9 Tz (sequence ) Tj 2.52 0 Td 47.6 Tz (of ) Tj 1.764 0 Td 36.711111 Tz (tionality ) Tj 2.016 0 Td 28 Tz (, ) Tj 0.3696 0 Td 35 Tz (e.g. ) Tj 0.924 0 Td 14 Tz (, ) Tj 0.2688 0 Td 42.933333 Tz (the ) Tj 0.9408 0 Td 42.8 Tz (disease ) Tj 1.9656 0 Td 40.88 Tz (resistance ) Tj 2.6376 0 Td 38.85 Tz (activity ) Tj 2.0496 0 Td 46.2 Tz (of ) Tj 0.6552 0 Td 42 Tz (the ) Tj 0.924 0 Td 42.933333 Tz (unaltered ) Tj 58.285714 0 0 58.285714 0 750.567506 Tm 5.558824 0 Td 64.814815 Tz (SEQ ) Tj 1.492647 0 Td 54.330065 Tz (ID ) Tj 0.960784 0 Td 75.776144 Tz (NO ) Tj 0.977941 0 Td 11.437908 Tz (: ) Tj 0.154412 0 Td 42.892157 Tz (3 ) Tj 0.343137 0 Td 11.437908 Tz (. ) Tj 0.428922 0 Td 44.321895 Tz (In ) Tj 0.823529 0 Td 43.527596 Tz (preferred ) Tj 2.659314 0 Td 52.250446 Tz (embodiments ) Tj 3.414216 0 Td 25.735294 Tz (, ) Tj 0.497549 0 Td 42.892157 Tz (the ) Tj 1.080882 0 Td 43.300654 Tz (protein ) Tj 2.127451 0 Td 32.883987 Tz (is ) Tj 1.75 0 Td 47.538807 Tz (sequence ) Tj 2.316176 0 Td 20.01634 Tz (. ) Tj 60.285714 0 0 60.285714 0 711.443306 Tm 5.341232 0 Td 44.628752 Tz (capable ) Tj 2.13981 0 Td 46.99842 Tz (of ) Tj 0.763033 0 Td 47.305599 Tz (improving ) Tj 2.819905 0 Td 41.469194 Tz (the ) Tj 1.011848 0 Td 41.864139 Tz (disease ) Tj 2.023697 0 Td 40.63981 Tz (resistance ) Tj 2.703791 0 Td 46.99842 Tz (of ) Tj 0.763033 0 Td 41.469194 Tz (a ) Tj 0.49763 0 Td 43.680885 Tz (plant ) Tj 1.194313 0 Td 27.64613 Tz (. ) Tj 0.464455 0 Td 42.851501 Tz (In ) Tj 2.405213 0 Td 42.851501 Tz (In ) Tj 0.696682 0 Td 52.527646 Tz (some ) Tj 1.42654 0 Td 42.083553 Tz (preferred ) Tj 2.438389 0 Td 50.768347 Tz (embodiments ) Tj 3.317536 0 Td 24.881517 Tz (, ) Tj 0.331754 0 Td 41.469194 Tz (a ) Tj 0.414692 0 Td 50.592417 Tz (homologous ) Tj 3.218009 0 Td 41.864139 Tz (protein ) Tj 1.924171 0 Td 46.99842 Tz (of ) Tj 70 0 0 70 0 664.465371 Tm 4.628571 0 Td 45.238095 Tz (some ) Tj 1.3 0 Td 34.126984 Tz (particularly ) Tj 2.657143 0 Td 36.243386 Tz (preferred ) Tj 2.042857 0 Td 45.021645 Tz (embodiments ) Tj 2.942857 0 Td 28.571429 Tz (, ) Tj 0.342857 0 Td 38.095238 Tz (the ) Tj 0.885714 0 Td 36.054422 Tz (protein ) Tj 1.742857 0 Td 36.309524 Tz (sub- ) Tj 1.228571 0 Td 30.952381 Tz (55 ) Tj 0.828571 0 Td 32.539683 Tz (the ) Tj 0.714286 0 Td 37.301587 Tz (invention ) Tj 2.142857 0 Td 33.673469 Tz (retains ) Tj 1.5 0 Td 47.619048 Tz (a ) Tj 0.442857 0 Td 33.571429 Tz (relatively ) Tj 2.157143 0 Td 39.880952 Tz (high ) Tj 1.114286 0 Td 33.333333 Tz (identity ) Tj 1.771429 0 Td 33.333333 Tz (in ) Tj 0.557143 0 Td 42.857143 Tz (amino ) Tj 1.471429 0 Td 36.309524 Tz (acid ) Tj 60 0 0 60 0 628.253521 Tm 5.4 0 Td 37.222222 Tz (stantially ) Tj 2.6 0 Td 38.888889 Tz (retains ) Tj 1.966667 0 Td 42.592593 Tz (the ) Tj 1.133333 0 Td 33.333333 Tz (full ) Tj 1.166667 0 Td 40.598291 Tz (functionality ) Tj 3.5 0 Td 50 Tz (of ) Tj 0.866667 0 Td 40.740741 Tz (the ) Tj 1.1 0 Td 34.722222 Tz (full ) Tj 0.916667 0 Td 27.777778 Tz (- ) Tj 0.25 0 Td 39.814815 Tz (length ) Tj 2.7 0 Td 42.013889 Tz (residues ) Tj 2.35 0 Td 45.512821 Tz (corresponding ) Tj 3.85 0 Td 37.5 Tz (to ) Tj 0.8 0 Td 48.148148 Tz (one ) Tj 1.2 0 Td 41.666667 Tz (or ) Tj 0.8 0 Td 52.777778 Tz (more ) Tj 1.583333 0 Td 47.222222 Tz (of ) Tj 0.8 0 Td 41.666667 Tz (the ) Tj 1.066667 0 Td 46.604938 Tz (conserved ) Tj 59.485714 0 0 59.485714 0 585.000652 Tm 5.396254 0 Td 42.427153 Tz (protein ) Tj 2.017291 0 Td 49.631764 Tz (encoded ) Tj 2.286263 0 Td 51.833173 Tz (by ) Tj 0.874159 0 Td 63.507311 Tz (SEQ ) Tj 1.378482 0 Td 53.23407 Tz (ID ) Tj 0.857349 0 Td 74.247518 Tz (NO ) Tj 0.958213 0 Td 11.207173 Tz (: ) Tj 0.151297 0 Td 42.026897 Tz (3 ) Tj 0.336215 0 Td 14.008966 Tz (, ) Tj 0.336215 0 Td 45.949408 Tz (while ) Tj 1.613833 0 Td 40.626001 Tz (in ) Tj 0.706052 0 Td 42.587256 Tz (other ) Tj 1.563401 0 Td 48.430996 Tz (embodi- ) Tj 3.32853 0 Td 41.746718 Tz (functional ) Tj 2.756964 0 Td 50.03202 Tz (domains ) Tj 2.353506 0 Td 48.751201 Tz (found ) Tj 1.681076 0 Td 40.626001 Tz (in ) Tj 0.689241 0 Td 44.82869 Tz (wild ) Tj 1.193564 0 Td 28.017931 Tz (- ) Tj 0.21854 0 Td 41.326449 Tz (type ) Tj 1.227185 0 Td 60.238553 Tz (FHB1 ) Tj 1.748319 0 Td 42.427153 Tz (protein ) Tj 1.815562 0 Td 14.008966 Tz (, ) Tj 0.353026 0 Td 35.022414 Tz (e.g. ) Tj 0.924592 0 Td 14.008966 Tz (, ) Tj 59.699248 0 0 59.699248 0 545.184459 Tm 5.393703 0 Td 49.135181 Tz (ments ) Tj 1.708564 0 Td 41.876574 Tz (the ) Tj 0.971537 0 Td 42.275399 Tz (protein ) Tj 1.993325 0 Td 45.366289 Tz (only ) Tj 1.306549 0 Td 38.464409 Tz (partially ) Tj 2.294836 0 Td 39.084803 Tz (retains ) Tj 1.876071 0 Td 41.876574 Tz (the ) Tj 0.988287 0 Td 40.588064 Tz (functionality ) Tj 3.400378 0 Td 47.460118 Tz (of ) Tj 1.758816 0 Td 41.876574 Tz (the ) Tj 1.021788 0 Td 42.155751 Tz (agglutinin ) Tj 2.780605 0 Td 44.668346 Tz (superfamily ) Tj 3.216121 0 Td 51.647775 Tz (domain ) Tj 2.110579 0 Td 48.390708 Tz (and ) Tj 0.954786 0 Td 22.334173 Tz (/ ) Tj 0.150756 0 Td 40.480688 Tz (or ) Tj 0.720277 0 Td 41.876574 Tz (the ) Tj 1.005038 0 Td 56.766023 Tz (ETX ) Tj 1.289798 0 Td 22.334173 Tz (/ ) Tj 58.571429 0 0 58.571429 0 543 Tm 35.597561 0 Td 75.406504 Tz (MTX2 ) Tj 59.931973 0 0 59.931973 0 503.497452 Tm 5.356073 0 Td 41.713961 Tz (the ) Tj 0.951078 0 Td 38.237798 Tz (full ) Tj 0.917707 0 Td 27.809308 Tz (- ) Tj 0.200227 0 Td 41.713961 Tz (length ) Tj 1.668558 0 Td 40.124858 Tz (protein ) Tj 1.718615 0 Td 27.809308 Tz (. ) Tj 0.400454 0 Td 40.323496 Tz (In ) Tj 0.700795 0 Td 52.837684 Tz (some ) Tj 1.468331 0 Td 50.309566 Tz (embodiments ) Tj 3.320431 0 Td 25.028377 Tz (, ) Tj 0.350397 0 Td 41.713961 Tz (the ) Tj 0.951078 0 Td 43.258923 Tz (invention ) Tj 3.654143 0 Td 44.494892 Tz (superfamily ) Tj 3.270375 0 Td 48.666288 Tz (domain ) Tj 1.835414 0 Td 27.809308 Tz (. ) Tj 0.56731 0 Td 46.348846 Tz (For ) Tj 1.167991 0 Td 50.056754 Tz (example ) Tj 2.069012 0 Td 27.809308 Tz (, ) Tj 0.56731 0 Td 36.1521 Tz (in ) Tj 0.800908 0 Td 41.404969 Tz (preferred ) Tj 2.636322 0 Td 57.472569 Tz (embodi ) Tj 64.285714 0 0 64.285714 0 457.72 Tm 5.008889 0 Td 41.157407 Tz (provides ) Tj 2.146667 0 Td 38.888889 Tz (a ) Tj 0.373333 0 Td 39.259259 Tz (protein ) Tj 1.773333 0 Td 43.425926 Tz (with ) Tj 1.182222 0 Td 44.074074 Tz (an ) Tj 0.668889 0 Td 46.342593 Tz (improved ) Tj 2.364444 0 Td 34.814815 Tz (ability ) Tj 1.586667 0 Td 36.296296 Tz (to ) Tj 0.606667 0 Td 41.049383 Tz (confer ) Tj 1.602222 0 Td 39.62963 Tz (disease ) Tj 2.053333 0 Td 33.703704 Tz (60 ) Tj 0.793333 0 Td 45.62963 Tz (ments ) Tj 1.524444 0 Td 38.888889 Tz (the ) Tj 0.871111 0 Td 47.185185 Tz (amino ) Tj 1.586667 0 Td 40.185185 Tz (acid ) Tj 1.088889 0 Td 39.212963 Tz (residues ) Tj 2.068889 0 Td 42.279202 Tz (corresponding ) Tj 3.437778 0 Td 36.296296 Tz (to ) Tj 0.606667 0 Td 45.802469 Tz (one ) Tj 0.98 0 Td 40.185185 Tz (or ) Tj 0.606667 0 Td 49.907407 Tz (more ) Tj 65.714286 0 0 65.714286 0 416.838213 Tm 4.9 0 Td 37.536232 Tz (resistance ) Tj 2.434783 0 Td 46.92029 Tz (compared ) Tj 2.434783 0 Td 35.507246 Tz (to ) Tj 0.63913 0 Td 37.40942 Tz (wild ) Tj 1.05 0 Td 25.362319 Tz (- ) Tj 0.197826 0 Td 38.043478 Tz (type ) Tj 1.126087 0 Td 54.528986 Tz (FHB1 ) Tj 1.582609 0 Td 38.405797 Tz (protein ) Tj 1.643478 0 Td 10.144928 Tz (. ) Tj 57.301587 0 0 57.301587 0 420.575871 Tm 22.634626 0 Td 49.445983 Tz (of ) Tj 0.715512 0 Td 44.210526 Tz (these ) Tj 1.535734 0 Td 43.628809 Tz (functional ) Tj 2.827147 0 Td 51.523546 Tz (domains ) Tj 2.390859 0 Td 42.65928 Tz (are ) Tj 0.977285 0 Td 41.043398 Tz (identical ) Tj 2.425762 0 Td 39.265928 Tz (to ) Tj 0.680609 0 Td 43.628809 Tz (the ) Tj 1.02964 0 Td 51.481994 Tz (correspond ) Tj 60.952381 0 0 60.952381 0 376.03316 Tm 5.922656 0 Td 41.015625 Tz (In ) Tj 0.721875 0 Td 51.953125 Tz (some ) Tj 1.476562 0 Td 50.213068 Tz (embodiments ) Tj 3.297656 0 Td 24.609375 Tz (, ) Tj 0.344531 0 Td 41.015625 Tz (the ) Tj 0.951562 0 Td 42.838542 Tz (invention ) Tj 2.510156 0 Td 43.408203 Tz (provides ) Tj 2.329687 0 Td 45.876736 Tz (conserved ) Tj 3.707812 0 Td 41.927083 Tz (ing ) Tj 0.984375 0 Td 45.269097 Tz (sequences ) Tj 2.674219 0 Td 47.03125 Tz (found ) Tj 1.624219 0 Td 38.28125 Tz (in ) Tj 0.65625 0 Td 43.066406 Tz (wild ) Tj 1.148438 0 Td 27.34375 Tz (- ) Tj 0.213281 0 Td 40.332031 Tz (type ) Tj 1.197656 0 Td 58.789062 Tz (FHB1 ) Tj 1.673437 0 Td 37.890625 Tz (protein ) Tj 1.70625 0 Td 27.34375 Tz (, ) Tj 0.39375 0 Td 42.382812 Tz (or ) Tj 0.705469 0 Td 34.179688 Tz (at ) Tj 0.639844 0 Td 36.640625 Tz (least ) Tj 58.831169 0 0 58.831169 0 338.337931 Tm 5.490287 0 Td 42.211185 Tz (functional ) Tj 2.753642 0 Td 50.183959 Tz (domains ) Tj 2.3117 0 Td 43.708609 Tz (present ) Tj 2.039735 0 Td 39.661516 Tz (in ) Tj 0.645916 0 Td 42.494481 Tz (the ) Tj 0.968874 0 Td 38.953274 Tz (full ) Tj 0.934879 0 Td 28.329654 Tz (- ) Tj 0.203974 0 Td 42.494481 Tz (length ) Tj 1.716777 0 Td 60.908756 Tz (FHB1 ) Tj 1.716777 0 Td 39.661516 Tz (protein ) Tj 1.76777 0 Td 28.329654 Tz (. ) Tj 1.512804 0 Td 43.061074 Tz (share ) Tj 1.495806 0 Td 39.661516 Tz (a ) Tj 0.441943 0 Td 39.661516 Tz (relatively ) Tj 2.583664 0 Td 46.743929 Tz (high ) Tj 1.325828 0 Td 46.271768 Tz (degree ) Tj 1.869757 0 Td 48.160412 Tz (of ) Tj 0.713907 0 Td 38.953274 Tz (identity ) Tj 1.835762 0 Td 28.329654 Tz (, ) Tj 0.373951 0 Td 43.061074 Tz (preferably ) Tj 2.787638 0 Td 36.82855 Tz (at ) Tj 0.679912 0 Td 37.395143 Tz (least ) Tj 59.162562 0 0 59.162562 0 292.233218 Tm 5.459534 0 Td 59.159034 Tz (Two ) Tj 1.284596 0 Td 47.890647 Tz (of ) Tj 0.693006 0 Td 42.819872 Tz (these ) Tj 1.487427 0 Td 47.264625 Tz (conserved ) Tj 2.738218 0 Td 49.902859 Tz (domains ) Tj 2.16353 0 Td 14.085484 Tz (, ) Tj 0.321149 0 Td 29.579517 Tz (i.e. ) Tj 0.777519 0 Td 14.085484 Tz (, ) Tj 0.304246 0 Td 42.256453 Tz (the ) Tj 0.912739 0 Td 45.636969 Tz (Agglutinin ) Tj 2.941049 0 Td 42.725969 Tz (super- ) Tj 2.839634 0 Td 47.890647 Tz (75 ) Tj 0.625396 0 Td 81.695809 Tz (% ) Tj 0.557785 0 Td 14.085484 Tz (, ) Tj 0.45637 0 Td 43.665001 Tz (or ) Tj 0.845129 0 Td 36.622259 Tz (at ) Tj 0.777519 0 Td 37.749098 Tz (least ) Tj 1.50433 0 Td 45.07355 Tz (85 ) Tj 0.608493 0 Td 81.695809 Tz (% ) Tj 0.540883 0 Td 14.085484 Tz (, ) Tj 0.473272 0 Td 42.256453 Tz (or ) Tj 0.845129 0 Td 35.213711 Tz (at ) Tj 0.777519 0 Td 37.749098 Tz (least ) Tj 1.487427 0 Td 46.482098 Tz (95 ) Tj 0.625396 0 Td 81.695809 Tz (% ) Tj 0.540883 0 Td 14.085484 Tz (, ) Tj 0.45637 0 Td 50.707744 Tz (and ) Tj 1.233888 0 Td 49.299195 Tz (even ) Tj 1.50433 0 Td 53.52484 Tz (more ) Tj 64.285714 0 0 64.285714 0 253.7201 Tm 5.024444 0 Td 41.481481 Tz (family ) Tj 1.68 0 Td 46.296296 Tz (domains ) Tj 1.991111 0 Td 12.962963 Tz (, ) Tj 0.295556 0 Td 30.462963 Tz (fall ) Tj 0.917778 0 Td 41.481481 Tz (within ) Tj 1.648889 0 Td 38.888889 Tz (the ) Tj 0.855556 0 Td 42 Tz (Agglutinin ) Tj 2.706667 0 Td 41.481481 Tz (superfamily ) Tj 2.691111 0 Td 25.925926 Tz (, ) Tj 0.342222 0 Td 46.666667 Tz (and ) Tj 1.213333 0 Td 32.407407 Tz (65 ) Tj 0.793333 0 Td 39.666667 Tz (preferably ) Tj 2.644444 0 Td 33.703704 Tz (at ) Tj 0.668889 0 Td 34.740741 Tz (least ) Tj 1.322222 0 Td 44.074074 Tz (99 ) Tj 0.56 0 Td 75.185185 Tz (% ) Tj 0.513333 0 Td 10.37037 Tz (. ) Tj 0.357778 0 Td 54.444444 Tz (By ) Tj 0.902222 0 Td 42.188552 Tz (maintaining ) Tj 3.048889 0 Td 38.888889 Tz (a ) Tj 0.482222 0 Td 36.296296 Tz (relatively ) Tj 2.442222 0 Td 43.425926 Tz (high ) Tj 60.204082 0 0 60.204082 0 211.167427 Tm 5.365085 0 Td 40.602637 Tz (are ) Tj 1.096271 0 Td 42.316384 Tz (present ) Tj 2.159322 0 Td 34.60452 Tz (at ) Tj 0.797288 0 Td 50.384181 Tz (amino ) Tj 1.893559 0 Td 42.909605 Tz (acid ) Tj 1.378644 0 Td 42.316384 Tz (residue ) Tj 2.142712 0 Td 40.910232 Tz (positions ) Tj 2.607797 0 Td 46.508475 Tz (7-166 ) Tj 1.461695 0 Td 13.841808 Tz (, ) Tj 0.481695 0 Td 49.830508 Tz (and ) Tj 2.142712 0 Td 45.216573 Tz (degree ) Tj 1.793898 0 Td 45.677966 Tz (of ) Tj 0.631186 0 Td 52.252825 Tz (homology ) Tj 2.674237 0 Td 38.757062 Tz (in ) Tj 0.597966 0 Td 42.079096 Tz (these ) Tj 1.411864 0 Td 42.711864 Tz (regions ) Tj 1.793898 0 Td 27.683616 Tz (, ) Tj 0.315593 0 Td 41.525424 Tz (the ) Tj 0.896949 0 Td 40.910232 Tz (retention ) Tj 2.358644 0 Td 47.062147 Tz (of ) Tj 0.647797 0 Td 42.316384 Tz (desired ) Tj 60.124224 0 0 60.124224 0 169.053254 Tm 5.422107 0 Td 46.72865 Tz (171-305 ) Tj 2.195455 0 Td 38.80854 Tz (in ) Tj 0.665289 0 Td 62.832874 Tz (SEQ ) Tj 1.330579 0 Td 51.282713 Tz (ID ) Tj 0.798347 0 Td 73.459022 Tz (NO ) Tj 0.948037 0 Td 11.088154 Tz (: ) Tj 0.133058 0 Td 41.580579 Tz (3 ) Tj 0.349277 0 Td 11.088154 Tz (. ) Tj 0.282748 0 Td 51.74472 Tz (The ) Tj 1.130992 0 Td 50.451102 Tz (amino ) Tj 1.71312 0 Td 42.966598 Tz (acid ) Tj 1.230785 0 Td 45.584634 Tz (sequences ) Tj 2.661157 0 Td 47.124656 Tz (of ) Tj 0.681921 0 Td 41.580579 Tz (the ) Tj 2.029132 0 Td 40.301176 Tz (functionality ) Tj 3.526033 0 Td 47.124656 Tz (can ) Tj 1.197521 0 Td 42.134986 Tz (often ) Tj 1.613326 0 Td 47.124656 Tz (be ) Tj 0.948037 0 Td 46.778151 Tz (enhanced ) Tj 2.328512 0 Td 19.40427 Tz (. ) Tj 0.515599 0 Td 46.01584 Tz (Conversely ) Tj 2.727686 0 Td 27.720386 Tz (, ) Tj 0.548864 0 Td 49.896694 Tz (undue ) Tj ET Q endstream endobj 185 0 obj << /Length 1 >> stream q endstream endobj 186 0 obj << /Length 57234 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 55.714286 0 0 55.714286 0 2967 Tm 13.44359 0 Td 68.803419 Tz (17 ) Tj 54.285714 0 0 54.285714 0 2969 Tm 31.739474 0 Td 67.54386 Tz (18 ) Tj 59.52381 0 0 59.52381 0 2913.825949 Tm 5.4264 0 Td 43.555556 Tz (departure ) Tj 2.5368 0 Td 50.4 Tz (from ) Tj 1.3608 0 Td 45.5 Tz (wild ) Tj 1.2096 0 Td 28 Tz (- ) Tj 0.2016 0 Td 41.3 Tz (type ) Tj 1.176 0 Td 50.96 Tz (amino ) Tj 1.7304 0 Td 43.4 Tz (acid ) Tj 1.2264 0 Td 47.25 Tz (sequence ) Tj 2.4528 0 Td 39.2 Tz (in ) Tj 0.6552 0 Td 46.977778 Tz (conserved ) Tj 3.8304 0 Td 37.8 Tz (struct ) Tj 1.5456 0 Td 46.355556 Tz (comprises ) Tj 2.7216 0 Td 42 Tz (a ) Tj 0.4368 0 Td 43.4 Tz (nucleotide ) Tj 2.8224 0 Td 47.25 Tz (sequence ) Tj 2.4528 0 Td 47.6 Tz (of ) Tj 0.7224 0 Td 63.466667 Tz (SEQ ) Tj 1.344 0 Td 51.8 Tz (ID ) Tj 0.8064 0 Td 74.2 Tz (NO ) Tj 0.9576 0 Td 11.2 Tz (: ) Tj 0.2016 0 Td 28 Tz (1 ) Tj 0.2856 0 Td 14 Tz (, ) Tj 0.3024 0 Td 44.8 Tz (2 ) Tj 0.336 0 Td 14 Tz (, ) Tj 58.457143 0 0 58.457143 0 2872.179195 Tm 5.525415 0 Td 42.481264 Tz (functional ) Tj 2.8739 0 Td 50.505051 Tz (domains ) Tj 2.42913 0 Td 49.41892 Tz (can ) Tj 1.163245 0 Td 43.12276 Tz (increase ) Tj 2.360704 0 Td 42.766373 Tz (the ) Tj 1.060606 0 Td 43.051483 Tz (likelihood ) Tj 2.8739 0 Td 48.468557 Tz (of ) Tj 0.804008 0 Td 39.915282 Tz (loss ) Tj 1.265885 0 Td 48.468557 Tz (of ) Tj 1.830401 0 Td 45.617465 Tz (4 ) Tj 0.342131 0 Td 14.255458 Tz (, ) Tj 0.393451 0 Td 39.915282 Tz (5 ) Tj 0.530303 0 Td 46.567829 Tz (and ) Tj 0.975073 0 Td 19.957641 Tz (/ ) Tj 0.153959 0 Td 41.340828 Tz (or ) Tj 0.752688 0 Td 42.766373 Tz (6 ) Tj 0.325024 0 Td 14.255458 Tz (, ) Tj 0.376344 0 Td 44.191919 Tz (or ) Tj 0.769795 0 Td 42.766373 Tz (a ) Tj 0.513196 0 Td 47.755784 Tz (fragment ) Tj 2.531769 0 Td 43.98827 Tz (thereof ) Tj 1.830401 0 Td 19.957641 Tz (. ) Tj 0.393451 0 Td 42.766373 Tz (In ) Tj 0.752688 0 Td 43.399949 Tz (preferred ) Tj 2.617302 0 Td 57.972195 Tz (embodi ) Tj 61.428571 0 0 61.428571 0 2836 Tm 5.25814 0 Td 38.610614 Tz (functionality ) Tj 58.571429 0 0 58.571429 0 2829.755236 Tm 22.126829 0 Td 49.512195 Tz (ments ) Tj 1.553659 0 Td 22.764228 Tz (, ) Tj 0.426829 0 Td 42.682927 Tz (the ) Tj 1.07561 0 Td 43.495935 Tz (nucleic ) Tj 2.168293 0 Td 43.394309 Tz (acid ) Tj 1.34878 0 Td 42.999097 Tz (construct ) Tj 2.646341 0 Td 47.109304 Tz (comprises ) Tj 2.885366 0 Td 42.682927 Tz (a ) Tj 0.563415 0 Td 44.390244 Tz (nucleotide ) Tj 58.739496 0 0 58.739496 0 2791.278357 Tm 6.14578 0 Td 44.546972 Tz (Functional ) Tj 2.928183 0 Td 42.966142 Tz (protein ) Tj 2.042918 0 Td 41.496781 Tz (variants ) Tj 2.264235 0 Td 46.816881 Tz (of ) Tj 0.732046 0 Td 43.506597 Tz (the ) Tj 1.038484 0 Td 44.137127 Tz (invention ) Tj 2.63877 0 Td 48.235575 Tz (can ) Tj 1.089557 0 Td 49.654268 Tz (be ) Tj 0.902289 0 Td 40.432761 Tz (pro- ) Tj 2.298283 0 Td 47.526228 Tz (sequence ) Tj 2.519599 0 Td 48.944921 Tz (encoding ) Tj 2.553648 0 Td 39.723414 Tz (a ) Tj 0.51073 0 Td 42.15546 Tz (protein ) Tj 2.042918 0 Td 45.398188 Tz (capable ) Tj 2.24721 0 Td 42.560801 Tz (of ) Tj 0.715021 0 Td 47.920309 Tz (improving ) Tj 2.826037 0 Td 43.776824 Tz (disease ) Tj 61.428571 0 0 61.428571 0 2747.108822 Tm 5.25814 0 Td 48.294574 Tz (duced ) Tj 1.660465 0 Td 50.193798 Tz (by ) Tj 0.846512 0 Td 47.028424 Tz (any ) Tj 1.106977 0 Td 44.767442 Tz (of ) Tj 0.716279 0 Td 40.697674 Tz (a ) Tj 0.472093 0 Td 40.310078 Tz (variety ) Tj 1.937209 0 Td 46.124031 Tz (of ) Tj 0.716279 0 Td 42.868217 Tz (techniques ) Tj 2.816279 0 Td 55.348837 Tz (known ) Tj 1.888372 0 Td 39.341085 Tz (in ) Tj 0.683721 0 Td 40.697674 Tz (the ) Tj 0.976744 0 Td 37.080103 Tz (art ) Tj 0.651163 0 Td 21.705426 Tz (, ) Tj 0.634884 0 Td 29.844961 Tz (5 ) Tj 0.732558 0 Td 39.883721 Tz (resistance ) Tj 2.604651 0 Td 46.124031 Tz (of ) Tj 0.683721 0 Td 40.697674 Tz (a ) Tj 0.439535 0 Td 44.496124 Tz (plant ) Tj 1.172093 0 Td 27.131783 Tz (, ) Tj 0.423256 0 Td 45.445736 Tz (such ) Tj 1.286047 0 Td 37.984496 Tz (as ) Tj 0.683721 0 Td 40.697674 Tz (a ) Tj 0.439535 0 Td 41.472868 Tz (protein ) Tj 1.937209 0 Td 45.852713 Tz (comprising ) Tj 2.669767 0 Td 27.131783 Tz (, ) Tj 0.488372 0 Td 43.023256 Tz (consist ) Tj 62 0 0 62 0 2707.763364 Tm 5.209677 0 Td 41.81601 Tz (including ) Tj 2.5 0 Td 31.586022 Tz (site ) Tj 0.887097 0 Td 18.817204 Tz (- ) Tj 0.16129 0 Td 39.650538 Tz (directed ) Tj 2.112903 0 Td 44.477028 Tz (mutagenesis ) Tj 2.935484 0 Td 26.88172 Tz (, ) Tj 0.403226 0 Td 71.684588 Tz (DNA ) Tj 1.5 0 Td 38.23178 Tz (shuffling ) Tj 2.032258 0 Td 26.88172 Tz (, ) Tj 0.419355 0 Td 46.594982 Tz (and ) Tj 0.951613 0 Td 18.817204 Tz (/ ) Tj 0.16129 0 Td 34.946237 Tz (or ) Tj 1.645161 0 Td 41.218638 Tz (ing ) Tj 0.790323 0 Td 13.44086 Tz (, ) Tj 0.306452 0 Td 41.666667 Tz (or ) Tj 0.677419 0 Td 40.322581 Tz (consisting ) Tj 2.612903 0 Td 38.367546 Tz (essentially ) Tj 2.725806 0 Td 45.698925 Tz (of ) Tj 0.693548 0 Td 60.9319 Tz (SEQ ) Tj 1.290323 0 Td 51.075269 Tz (ID ) Tj 0.806452 0 Td 71.236559 Tz (NO ) Tj 0.919355 0 Td 10.752688 Tz (: ) Tj 0.129032 0 Td 40.322581 Tz (3 ) Tj 0.322581 0 Td 13.44086 Tz (, ) Tj 0.306452 0 Td 43.010753 Tz (7 ) Tj 0.322581 0 Td 13.44086 Tz (, ) Tj 0.322581 0 Td 40.322581 Tz (8 ) Tj 0.451613 0 Td 41.666667 Tz (or ) Tj 0.693548 0 Td 32.258065 Tz (9. ) Tj 0.612903 0 Td 40.322581 Tz (In ) Tj 54.428571 0 0 54.428571 0 2667.018821 Tm 5.934383 0 Td 45.931759 Tz (directed ) Tj 2.461942 0 Td 46.271994 Tz (evolution ) Tj 2.572178 0 Td 21.434821 Tz (. ) Tj 0.422572 0 Td 42.869641 Tz (If ) Tj 0.67979 0 Td 45.591523 Tz (retention ) Tj 2.700787 0 Td 52.055993 Tz (of ) Tj 0.826772 0 Td 47.462817 Tz (function ) Tj 2.51706 0 Td 35.214348 Tz (is ) Tj 0.698163 0 Td 45.056868 Tz (desired ) Tj 1.929134 0 Td 27.559055 Tz (, ) Tj 0.532808 0 Td 48.993876 Tz (con- ) Tj 2.572178 0 Td 58.180227 Tz (some ) Tj 1.598425 0 Td 55.396485 Tz (embodiments ) Tj 3.87664 0 Td 45.931759 Tz (a ) Tj 0.459318 0 Td 46.806649 Tz (nucleic ) Tj 2.186352 0 Td 46.697288 Tz (acid ) Tj 1.322835 0 Td 45.931759 Tz (construct ) Tj 2.682415 0 Td 52.055993 Tz (of ) Tj 0.734908 0 Td 45.931759 Tz (the ) Tj 1.028871 0 Td 47.632935 Tz (invention ) Tj 65.037594 0 0 65.037594 0 2623.055419 Tm 4.981734 0 Td 37.869835 Tz (servative ) Tj 2.183353 0 Td 46.639692 Tz (amino ) Tj 1.568324 0 Td 39.079961 Tz (acid ) Tj 1.091676 0 Td 36.665185 Tz (substitutions ) Tj 3.013642 0 Td 37.5851 Tz (are ) Tj 0.830289 0 Td 39.008778 Tz (generally ) Tj 2.244855 0 Td 38.439306 Tz (preferred ) Tj 2.091098 0 Td 25.626204 Tz (. ) Tj 0.292139 0 Td 39.720617 Tz (In ) Tj 1.645202 0 Td 42.425605 Tz (comprises ) Tj 2.536994 0 Td 38.439306 Tz (a ) Tj 0.43052 0 Td 44.205202 Tz (promoter ) Tj 2.352486 0 Td 42.923892 Tz (sequence ) Tj 2.290983 0 Td 42.71034 Tz (and ) Tj 0.891792 0 Td 17.938343 Tz (/ ) Tj 0.184509 0 Td 32.032755 Tz (or ) Tj 0.584277 0 Td 39.208092 Tz (regulatory ) Tj 2.567746 0 Td 43.198459 Tz (element ) Tj 1.829711 0 Td 17.938343 Tz (. ) Tj 64.887218 0 0 64.887218 0 2578.767518 Tm 4.977868 0 Td 39.555813 Tz (other ) Tj 1.47949 0 Td 46.467573 Tz (embodiments ) Tj 3.082271 0 Td 23.117034 Tz (, ) Tj 0.462341 0 Td 36.216686 Tz (alteration ) Tj 2.481228 0 Td 43.665508 Tz (of ) Tj 0.770568 0 Td 39.812669 Tz (function ) Tj 2.219235 0 Td 29.538432 Tz (is ) Tj 0.662688 0 Td 38.528389 Tz (the ) Tj 1.017149 0 Td 39.6292 Tz (desired ) Tj 2.835689 0 Td 39.555813 Tz (Preferably ) Tj 2.342526 0 Td 25.685593 Tz (, ) Tj 0.385284 0 Td 38.528389 Tz (the ) Tj 0.940093 0 Td 43.986578 Tz (promoter ) Tj 2.373349 0 Td 43.023368 Tz (sequence ) Tj 2.327115 0 Td 28.254152 Tz (is ) Tj 0.616454 0 Td 41.418019 Tz (operably ) Tj 2.250058 0 Td 39.812669 Tz (linked ) Tj 1.649015 0 Td 35.95983 Tz (to ) Tj 0.708922 0 Td 38.528389 Tz (a ) Tj 62.857143 0 0 62.857143 0 2539.032609 Tm 5.138636 0 Td 40.06734 Tz (objective ) Tj 2.115909 0 Td 26.515152 Tz (, ) Tj 0.397727 0 Td 37.121212 Tz (in ) Tj 0.620455 0 Td 48.787879 Tz (which ) Tj 1.654545 0 Td 41.761364 Tz (case ) Tj 1.193182 0 Td 45.075758 Tz (non ) Tj 1.018182 0 Td 18.560606 Tz (- ) Tj 0.159091 0 Td 40.435606 Tz (conservative ) Tj 3.134091 0 Td 37.937063 Tz (substitutions ) Tj 3.165909 0 Td 45.959596 Tz (can ) Tj 1.225 0 Td 33.143939 Tz (10 ) Tj 0.795455 0 Td 40.151515 Tz (nucleic ) Tj 1.861364 0 Td 41.098485 Tz (acid ) Tj 1.145455 0 Td 44.412879 Tz (sequence ) Tj 2.290909 0 Td 44.744318 Tz (encoding ) Tj 2.306818 0 Td 39.772727 Tz (a ) Tj 0.381818 0 Td 40.151515 Tz (protein ) Tj 1.829545 0 Td 42.80303 Tz (capable ) Tj 1.940909 0 Td 45.075758 Tz (of ) Tj 0.652273 0 Td 52.146465 Tz (improv ) Tj 60.952381 0 0 60.952381 0 2500.472222 Tm 5.266406 0 Td 50.585938 Tz (be ) Tj 0.803906 0 Td 41.512784 Tz (appropriate ) Tj 2.739844 0 Td 32.8125 Tz (. ) Tj 64.047619 0 0 64.047619 0 2497.920817 Tm 20.250558 0 Td 39.900867 Tz (ing ) Tj 0.92119 0 Td 39.405204 Tz (disease ) Tj 1.826766 0 Td 38.252788 Tz (resistance ) Tj 2.498141 0 Td 42.936803 Tz (of ) Tj 0.655762 0 Td 39.033457 Tz (a ) Tj 0.405948 0 Td 39.033457 Tz (plant ) Tj 1.139777 0 Td 26.022305 Tz (, ) Tj 0.374721 0 Td 43.587361 Tz (such ) Tj 1.217844 0 Td 37.732342 Tz (as ) Tj 0.655762 0 Td 39.033457 Tz (a ) Tj 0.405948 0 Td 39.776952 Tz (protein ) Tj 1.873606 0 Td 49.442379 Tz (compris ) Tj 60 0 0 60 0 2457.143894 Tm 6.016667 0 Td 41.666667 Tz (In ) Tj 0.85 0 Td 52.777778 Tz (some ) Tj 1.616667 0 Td 50.252525 Tz (embodiments ) Tj 3.316667 0 Td 25 Tz (, ) Tj 0.5 0 Td 42.592593 Tz (the ) Tj 1.1 0 Td 43.518519 Tz (invention ) Tj 2.666667 0 Td 44.097222 Tz (provides ) Tj 2.466667 0 Td 42.460317 Tz (nucleic ) Tj 3.083333 0 Td 42.592593 Tz (ing ) Tj 0.816667 0 Td 13.888889 Tz (, ) Tj 0.283333 0 Td 41.666667 Tz (consisting ) Tj 2.533333 0 Td 13.888889 Tz (, ) Tj 0.283333 0 Td 43.055556 Tz (or ) Tj 0.666667 0 Td 41.666667 Tz (consisting ) Tj 2.666667 0 Td 39.646465 Tz (essentially ) Tj 2.783333 0 Td 47.222222 Tz (of ) Tj 0.683333 0 Td 62.037037 Tz (SEQ ) Tj 1.3 0 Td 51.388889 Tz (ID ) Tj 0.783333 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.133333 0 Td 41.666667 Tz (3 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 0.283333 0 Td 44.444444 Tz (7 ) Tj 0.333333 0 Td 13.888889 Tz (, ) Tj 56.666667 0 0 56.666667 0 2414.38293 Tm 5.7 0 Td 43.529412 Tz (acids ) Tj 1.552941 0 Td 47.058824 Tz (capable ) Tj 2.188235 0 Td 50 Tz (of ) Tj 0.741176 0 Td 50.326797 Tz (improving ) Tj 2.947059 0 Td 44.537815 Tz (disease ) Tj 2.064706 0 Td 43.235294 Tz (resistance ) Tj 2.805882 0 Td 42.647059 Tz (in ) Tj 0.705882 0 Td 44.117647 Tz (a ) Tj 0.458824 0 Td 44.705882 Tz (plant ) Tj 1.288235 0 Td 29.411765 Tz (. ) Tj 0.352941 0 Td 58.823529 Tz (As ) Tj 2.082353 0 Td 47.058824 Tz (8 ) Tj 0.529412 0 Td 47.058824 Tz (or ) Tj 0.794118 0 Td 47.058824 Tz (9 ) Tj 0.317647 0 Td 17.647059 Tz (. ) Tj 61.22449 0 0 61.22449 0 2373.657792 Tm 5.259333 0 Td 46.958333 Tz (used ) Tj 1.274 0 Td 40.833333 Tz (herein ) Tj 1.519 0 Td 24.5 Tz (, ) Tj 0.310333 0 Td 40.833333 Tz (the ) Tj 0.914667 0 Td 44.1 Tz (terms ) Tj 1.519 0 Td 16.333333 Tz ( ) Tj 0.147 0 Td 43.944444 Tz (nucleic ) Tj 2.041667 0 Td 38.111111 Tz (acid ) Tj 1.029 0 Td 24.5 Tz (, ) Tj 0.245 0 Td 24.5 Tz ( ) Tj 0.326667 0 Td 16.333333 Tz ( ) Tj 0.147 0 Td 45.888889 Tz (polynucleotide ) Tj 3.903667 0 Td 16.333333 Tz (, ) Tj 0.147 0 Td 16.333333 Tz ( ) Tj 0.277667 0 Td 49 Tz (and ) Tj 2.727667 0 Td 51.722222 Tz (The ) Tj 1.143333 0 Td 46.277778 Tz (term ) Tj 1.323 0 Td 35.388889 Tz ( ) Tj 0.310333 0 Td 46.618056 Tz (promoter ) Tj 2.188667 0 Td 35.388889 Tz ( ) Tj 0.49 0 Td 40.833333 Tz (or ) Tj 0.702333 0 Td 16.333333 Tz ( ) Tj 0.147 0 Td 43.283333 Tz (regulatory ) Tj 2.842 0 Td 47.833333 Tz (element ) Tj 1.927333 0 Td 35.388889 Tz ( ) Tj 0.441 0 Td 38.111111 Tz (refers ) Tj 1.600667 0 Td 36.75 Tz (to ) Tj 0.686 0 Td 40.833333 Tz (a ) Tj 60 0 0 60 0 2332.245813 Tm 5.416667 0 Td 33.333333 Tz ( ) Tj 0.266667 0 Td 72.222222 Tz (DNA ) Tj 1.333333 0 Td 33.333333 Tz ( ) Tj 0.4 0 Td 40.740741 Tz (are ) Tj 0.883333 0 Td 47.916667 Tz (used ) Tj 1.283333 0 Td 43.518519 Tz (interchangeably ) Tj 3.883333 0 Td 27.777778 Tz (, ) Tj 0.333333 0 Td 42.592593 Tz (unless ) Tj 1.716667 0 Td 41.975309 Tz (indicated ) Tj 2.416667 0 Td 44.444444 Tz (otherwise ) Tj 2.833333 0 Td 33.333333 Tz (15 ) Tj 0.833333 0 Td 44.444444 Tz (region ) Tj 1.766667 0 Td 43.055556 Tz (or ) Tj 0.7 0 Td 46.875 Tz (sequence ) Tj 2.433333 0 Td 44.212963 Tz (determinants ) Tj 3.4 0 Td 42.460317 Tz (located ) Tj 1.95 0 Td 47.569444 Tz (upstream ) Tj 2.466667 0 Td 41.666667 Tz (or ) Tj 0.766667 0 Td 61.805556 Tz (down ) Tj 57.792208 0 0 57.792208 0 2289.775434 Tm 5.571685 0 Td 53.35206 Tz (by ) Tj 0.847865 0 Td 46.142322 Tz (context ) Tj 1.937978 0 Td 17.303371 Tz (. ) Tj 0.311461 0 Td 44.700375 Tz (In ) Tj 0.744045 0 Td 55.514981 Tz (some ) Tj 1.54 0 Td 52.434457 Tz (embodiments ) Tj 3.443371 0 Td 25.955056 Tz (, ) Tj 0.380674 0 Td 43.258427 Tz (a ) Tj 0.467191 0 Td 43.670412 Tz (nucleic ) Tj 2.059101 0 Td 44.700375 Tz (acid ) Tj 1.263146 0 Td 44.700375 Tz (or ) Tj 0.709438 0 Td 44.082397 Tz (protein ) Tj 3.18382 0 Td 47.10362 Tz (stream ) Tj 1.851461 0 Td 51.189139 Tz (from ) Tj 1.38427 0 Td 43.258427 Tz (the ) Tj 0.968989 0 Td 35.7603 Tz (start ) Tj 1.228539 0 Td 49.026217 Tz (of ) Tj 0.657528 0 Td 42.149237 Tz (transcription ) Tj 3.443371 0 Td 50.948814 Tz (and ) Tj 1.055506 0 Td 53.06367 Tz (which ) Tj 1.730337 0 Td 42.297129 Tz (are ) Tj 0.934382 0 Td 46.863296 Tz (involved ) Tj 60.248447 0 0 60.248447 0 2248.725981 Tm 5.361134 0 Td 47.027491 Tz (of ) Tj 0.813299 0 Td 41.494845 Tz (the ) Tj 1.095464 0 Td 43.339061 Tz (invention ) Tj 2.65567 0 Td 31.812715 Tz (is ) Tj 0.730309 0 Td 27.66323 Tz ( ) Tj 0.331959 0 Td 37.345361 Tz (isolated ) Tj 1.908763 0 Td 19.364261 Tz (. ) Tj 0.248969 0 Td 22.130584 Tz ( ) Tj 0.414948 0 Td 55.32646 Tz (As ) Tj 1.012474 0 Td 47.027491 Tz (used ) Tj 1.444021 0 Td 41.955899 Tz (herein ) Tj 1.543608 0 Td 24.896907 Tz (, ) Tj 0.48134 0 Td 41.494845 Tz (the ) Tj 1.078866 0 Td 47.027491 Tz (term ) Tj 2.406701 0 Td 38.728522 Tz (in ) Tj 0.713711 0 Td 43.003749 Tz (recognition ) Tj 3.087216 0 Td 48.871707 Tz (and ) Tj 1.12866 0 Td 45.051546 Tz (binding ) Tj 2.157732 0 Td 47.027491 Tz (of ) Tj 0.763505 0 Td 71.924399 Tz (RNA ) Tj 1.510412 0 Td 47.580756 Tz (polymerase ) Tj 3.120412 0 Td 49.793814 Tz (and ) Tj 1.145258 0 Td 42.601375 Tz (other ) Tj 61.547619 0 0 61.547619 0 2206.488961 Tm 5.247969 0 Td 24.371373 Tz ( ) Tj 0.389942 0 Td 34.526112 Tz (isolated ) Tj 1.900967 0 Td 18.955513 Tz ( ) Tj 0.341199 0 Td 37.459703 Tz (refers ) Tj 1.592263 0 Td 36.55706 Tz (to ) Tj 0.698646 0 Td 40.618956 Tz (a ) Tj 0.487427 0 Td 42.588359 Tz (synthesized ) Tj 2.794584 0 Td 27.079304 Tz (, ) Tj 0.389942 0 Td 44.680851 Tz (cloned ) Tj 1.641006 0 Td 13.539652 Tz (, ) Tj 0.341199 0 Td 46.034816 Tz (and ) Tj 0.94236 0 Td 18.955513 Tz (/ ) Tj 0.146228 0 Td 37.911025 Tz (or ) Tj 0.649903 0 Td 42.123361 Tz (truncated ) Tj 3.49323 0 Td 40.280464 Tz (proteins ) Tj 2.177176 0 Td 36.55706 Tz (to ) Tj 0.698646 0 Td 34.864603 Tz (initiate ) Tj 1.900967 0 Td 38.952537 Tz (transcription ) Tj 3.038298 0 Td 27.079304 Tz (. ) Tj 0.422437 0 Td 45.433054 Tz (Promoters ) Tj 2.697099 0 Td 48.065764 Tz (need ) Tj 1.364797 0 Td 42.424242 Tz (not ) Tj 0.991103 0 Td 47.388781 Tz (be ) Tj 0.812379 0 Td 46.034816 Tz (of ) Tj 62.857143 0 0 62.857143 0 2167.34033 Tm 5.154545 0 Td 44.744318 Tz (sequence ) Tj 2.370455 0 Td 47.064394 Tz (from ) Tj 1.336364 0 Td 39.772727 Tz (the ) Tj 0.922727 0 Td 38.888889 Tz (naturally ) Tj 2.338636 0 Td 41.540404 Tz (occurring ) Tj 2.481818 0 Td 45.075758 Tz (sequence ) Tj 2.163636 0 Td 18.560606 Tz (. ) Tj 65.714286 0 0 65.714286 0 2167.754617 Tm 19.721739 0 Td 37.536232 Tz (plant ) Tj 1.445652 0 Td 36.352657 Tz (origin ) Tj 1.293478 0 Td 25.362319 Tz (, ) Tj 0.502174 0 Td 36.352657 Tz (for ) Tj 0.943478 0 Td 45.652174 Tz (example ) Tj 1.902174 0 Td 25.362319 Tz (, ) Tj 0.441304 0 Td 42.552335 Tz (promoters ) Tj 2.617391 0 Td 40.57971 Tz (derived ) Tj 2.008696 0 Td 45.018116 Tz (from ) Tj 1.369565 0 Td 38.043478 Tz (plant ) Tj 61.428571 0 0 61.428571 0 2121.437381 Tm 5.876744 0 Td 40.697674 Tz (In ) Tj 0.732558 0 Td 40.697674 Tz (a ) Tj 0.504651 0 Td 41.300603 Tz (preferred ) Tj 2.474419 0 Td 51.550388 Tz (embodiment ) Tj 2.995349 0 Td 24.418605 Tz (, ) Tj 0.423256 0 Td 40.697674 Tz (the ) Tj 0.993023 0 Td 41.085271 Tz (nucleic ) Tj 2.002326 0 Td 42.054264 Tz (acid ) Tj 1.253488 0 Td 46.124031 Tz (comprises ) Tj 2.44186 0 Td 27.131783 Tz (, ) Tj 0.553488 0 Td 36.627907 Tz (20 ) Tj 0.846512 0 Td 41.085271 Tz (viruses ) Tj 1.693023 0 Td 24.418605 Tz (, ) Tj 0.374419 0 Td 45.445736 Tz (such ) Tj 1.269767 0 Td 39.341085 Tz (as ) Tj 0.667442 0 Td 40.697674 Tz (the ) Tj 0.911628 0 Td 61.24031 Tz (CaMV35S ) Tj 2.767442 0 Td 46.124031 Tz (promoter ) Tj 2.197674 0 Td 24.418605 Tz (, ) Tj 0.34186 0 Td 46.124031 Tz (can ) Tj 0.993023 0 Td 47.48062 Tz (be ) Tj 0.732558 0 Td 46.802326 Tz (used ) Tj 1.302326 0 Td 39.341085 Tz (in ) Tj 0.618605 0 Td 41.602067 Tz (the ) Tj 60.873016 0 0 60.873016 0 2081.950158 Tm 5.306128 0 Td 39.70013 Tz (consists ) Tj 2.152021 0 Td 46.54498 Tz (of ) Tj 0.459974 0 Td 24.64146 Tz (, ) Tj 0.410691 0 Td 42.43807 Tz (or ) Tj 0.706389 0 Td 39.70013 Tz (consists ) Tj 2.152021 0 Td 39.077871 Tz (essentially ) Tj 2.809126 0 Td 45.17601 Tz (of ) Tj 0.706389 0 Td 41.0691 Tz (a ) Tj 0.459974 0 Td 41.851369 Tz (nucleic ) Tj 2.004172 0 Td 41.753585 Tz (acid ) Tj 1.199218 0 Td 46.54498 Tz (having ) Tj 2.92412 0 Td 42.242503 Tz (present ) Tj 2.053455 0 Td 41.677532 Tz (invention ) Tj 2.29987 0 Td 19.16558 Tz (. ) Tj 0.459974 0 Td 41.0691 Tz (Suitable ) Tj 2.250587 0 Td 45.632334 Tz (promoters ) Tj 2.759844 0 Td 42.633638 Tz (include ) Tj 2.08631 0 Td 39.471969 Tz (constitutive ) Tj 59.220779 0 0 59.220779 0 2042.321113 Tm 5.437281 0 Td 42.214912 Tz (the ) Tj 0.945614 0 Td 43.622076 Tz (nucleotide ) Tj 2.836842 0 Td 47.139985 Tz (sequence ) Tj 2.465351 0 Td 46.436404 Tz (of ) Tj 0.709211 0 Td 62.853314 Tz (SEQ ) Tj 1.333991 0 Td 53.472222 Tz (ID ) Tj 0.827412 0 Td 74.579678 Tz (NO ) Tj 0.9625 0 Td 11.25731 Tz (: ) Tj 0.185746 0 Td 28.143275 Tz (1 ) Tj 0.455921 0 Td 30.957602 Tz (\( ) Tj 0.236404 0 Td 45.462213 Tz (corresponding ) Tj 3.714912 0 Td 39.400585 Tz (to ) Tj 1.773026 0 Td 47.530864 Tz (promoters ) Tj 2.532895 0 Td 25.328947 Tz (, ) Tj 0.405263 0 Td 39.400585 Tz (as ) Tj 0.692325 0 Td 44.325658 Tz (well ) Tj 1.300219 0 Td 40.807749 Tz (as ) Tj 0.709211 0 Td 46.905458 Tz (promoters ) Tj 2.769298 0 Td 44.747807 Tz (responsive ) Tj 2.8875 0 Td 39.400585 Tz (to ) Tj 0.692325 0 Td 42.214912 Tz (the ) Tj 0.9625 0 Td 46.084613 Tz (presence ) Tj 60 0 0 60 0 1999.879799 Tm 5.383333 0 Td 50 Tz (genomic ) Tj 2.366667 0 Td 49.305556 Tz (Fhbl ) Tj 1.516667 0 Td 47.222222 Tz (sequence ) Tj 2.383333 0 Td 27.777778 Tz (\) ) Tj 0.033333 0 Td 27.777778 Tz (, ) Tj 0.433333 0 Td 41.666667 Tz (the ) Tj 0.983333 0 Td 43.055556 Tz (nucleotide ) Tj 2.85 0 Td 46.527778 Tz (sequence ) Tj 2.483333 0 Td 47.222222 Tz (of ) Tj 0.766667 0 Td 62.037037 Tz (SEQ ) Tj 2.416667 0 Td 47.222222 Tz (of ) Tj 0.716667 0 Td 42.063492 Tz (disease ) Tj 2 0 Td 49.074074 Tz (and ) Tj 0.966667 0 Td 19.444444 Tz (/ ) Tj 0.166667 0 Td 37.5 Tz (or ) Tj 0.65 0 Td 39.506173 Tz (infection ) Tj 2.166667 0 Td 25 Tz (, ) Tj 0.383333 0 Td 39.814815 Tz (particularly ) Tj 3.1 0 Td 64.814815 Tz (FHB ) Tj 1.25 0 Td 11.111111 Tz (. ) Tj 0.3 0 Td 60.185185 Tz (Non ) Tj 1.1 0 Td 25 Tz (- ) Tj 0.2 0 Td 40.625 Tz (limiting ) Tj 61.818182 0 0 61.818182 0 1958.718967 Tm 5.225 0 Td 51.22549 Tz (ID ) Tj 0.825 0 Td 71.446078 Tz (NO ) Tj 0.922059 0 Td 10.784314 Tz (: ) Tj 0.129412 0 Td 43.137255 Tz (2 ) Tj 0.517647 0 Td 35.04902 Tz (\( ) Tj 0.275 0 Td 42.929864 Tz (corresponding ) Tj 3.558824 0 Td 36.397059 Tz (to ) Tj 0.663235 0 Td 40.441176 Tz (the ) Tj 0.954412 0 Td 47.855392 Tz (Fhb1 ) Tj 1.439706 0 Td 64.705882 Tz (cDNA ) Tj 1.747059 0 Td 46.170343 Tz (sequence ) Tj 2.264706 0 Td 26.960784 Tz (\) ) Tj 0.113235 0 Td 26.960784 Tz (, ) Tj 0.355882 0 Td 41.339869 Tz (the ) Tj 1.989706 0 Td 46.844363 Tz (examples ) Tj 2.491176 0 Td 45.833333 Tz (of ) Tj 0.711765 0 Td 44.934641 Tz (promoters ) Tj 2.669118 0 Td 41.981793 Tz (include ) Tj 1.989706 0 Td 47.45098 Tz (maize ) Tj 1.65 0 Td 40.441176 Tz (ubiquitin ) Tj 2.394118 0 Td 44.934641 Tz (promoters ) Tj 2.458824 0 Td 24.264706 Tz (, ) Tj 61.428571 0 0 61.428571 0 1916.289149 Tm 5.24186 0 Td 42.054264 Tz (nucleotide ) Tj 2.734884 0 Td 45.445736 Tz (sequence ) Tj 2.376744 0 Td 46.124031 Tz (of ) Tj 0.683721 0 Td 61.498708 Tz (SEQ ) Tj 1.302326 0 Td 50.193798 Tz (ID ) Tj 0.781395 0 Td 71.899225 Tz (NO ) Tj 0.927907 0 Td 10.852713 Tz (: ) Tj 0.130233 0 Td 43.410853 Tz (4 ) Tj 0.488372 0 Td 27.131783 Tz (\( ) Tj 0.211628 0 Td 44.036971 Tz (corresponding ) Tj 3.613953 0 Td 36.627907 Tz (to ) Tj 0.634884 0 Td 40.697674 Tz (the ) Tj 1.123256 0 Td 35.271318 Tz (25 ) Tj 0.846512 0 Td 45.445736 Tz (high ) Tj 1.318605 0 Td 45.521102 Tz (molecular ) Tj 2.686047 0 Td 45.671835 Tz (weight ) Tj 1.937209 0 Td 27.131783 Tz (\( ) Tj 0.17907 0 Td 85.917313 Tz (HMW ) Tj 1.562791 0 Td 27.131783 Tz (\) ) Tj 0.439535 0 Td 41.375969 Tz (glutenin ) Tj 2.230233 0 Td 46.802326 Tz (promoter ) Tj 2.506977 0 Td 41.860465 Tz (subunit ) Tj 61.746032 0 0 61.746032 0 1877.127092 Tm 5.231105 0 Td 45.212082 Tz (sequence ) Tj 2.461697 0 Td 45.886889 Tz (encoding ) Tj 2.526478 0 Td 30.231362 Tz (first ) Tj 1.198458 0 Td 40.488432 Tz (agglutinin ) Tj 2.720823 0 Td 43.187661 Tz (superfamily ) Tj 3.174293 0 Td 44.987147 Tz (conserved ) Tj 3.70874 0 Td 26.992288 Tz (\( ) Tj 0.178149 0 Td 55.33419 Tz (Dy10 ) Tj 1.360411 0 Td 26.992288 Tz (\) ) Tj 0.21054 0 Td 13.496144 Tz (, ) Tj 0.291517 0 Td 40.488432 Tz (the ) Tj 0.923136 0 Td 60.539846 Tz (CaMV35S ) Tj 2.737018 0 Td 47.911311 Tz (promoter ) Tj 2.17018 0 Td 24.293059 Tz (, ) Tj 0.356298 0 Td 40.488432 Tz (the ) Tj 0.939332 0 Td 46.658098 Tz (soybean ) Tj 2.137789 0 Td 55.33419 Tz (GMubi3 ) Tj 2.251157 0 Td 55.784062 Tz (pro ) Tj 58.469388 0 0 58.469388 0 1831.012089 Tm 5.524258 0 Td 53.20923 Tz (domain ) Tj 1.932635 0 Td 14.252472 Tz (, ) Tj 0.495986 0 Td 30.642816 Tz (i.e. ) Tj 0.803839 0 Td 14.252472 Tz (, ) Tj 0.478883 0 Td 45.037813 Tz (bases ) Tj 1.761606 0 Td 48.933488 Tz (69-377 ) Tj 2.154974 0 Td 47.033159 Tz (of ) Tj 0.889354 0 Td 64.611208 Tz (SEQ ) Tj 1.539267 0 Td 54.159395 Tz (ID ) Tj 1.009075 0 Td 75.538104 Tz (NO ) Tj 0.974869 0 Td 11.401978 Tz (: ) Tj 0.205236 0 Td 28.504945 Tz (1 ) Tj 0.29075 0 Td 14.252472 Tz (, ) Tj 0.46178 0 Td 52.449098 Tz (which ) Tj 1.932635 0 Td 32.780686 Tz (is ) Tj 1.710297 0 Td 51.308901 Tz (moter ) Tj 1.505061 0 Td 22.803956 Tz (, ) Tj 0.273647 0 Td 46.558076 Tz (and ) Tj 0.957766 0 Td 19.953461 Tz (/ ) Tj 0.17103 0 Td 41.33217 Tz (or ) Tj 0.615707 0 Td 39.906923 Tz (rice ) Tj 1.111693 0 Td 41.04712 Tz (actin ) Tj 1.368237 0 Td 48.814718 Tz (promoter ) Tj 2.308901 0 Td 25.65445 Tz (. ) Tj 0.307853 0 Td 42.757417 Tz (In ) Tj 0.684119 0 Td 54.159395 Tz (some ) Tj 1.453752 0 Td 43.39086 Tz (preferred ) Tj 2.599651 0 Td 55.10956 Tz (embodi ) Tj 64.904762 0 0 64.904762 0 1787.000627 Tm 4.976522 0 Td 39.801908 Tz (equivalent ) Tj 2.526779 0 Td 34.666178 Tz (to ) Tj 0.570066 0 Td 41.08584 Tz (bases ) Tj 1.448276 0 Td 42.79775 Tz (19-498 ) Tj 1.725605 0 Td 42.369773 Tz (of ) Tj 0.631695 0 Td 57.348985 Tz (SEQ ) Tj 1.201761 0 Td 47.505503 Tz (ID ) Tj 0.724138 0 Td 68.048423 Tz (NO ) Tj 0.87821 0 Td 10.27146 Tz (: ) Tj 0.123258 0 Td 41.08584 Tz (2 ) Tj 0.292737 0 Td 25.67865 Tz (\) ) Tj 0.215701 0 Td 12.839325 Tz (, ) Tj 0.277329 0 Td 57.348985 Tz (SEQ ) Tj 1.201761 0 Td 47.505503 Tz (ID ) Tj 0.724138 0 Td 68.048423 Tz (NO ) Tj 0.87821 0 Td 10.27146 Tz (: ) Tj 0.154072 0 Td 35.95011 Tz (5 ) Tj 1.417461 0 Td 46.22157 Tz (ments ) Tj 1.340426 0 Td 28.246515 Tz (, ) Tj 0.323551 0 Td 38.517975 Tz (a ) Tj 0.369773 0 Td 42.369773 Tz (pathogen ) Tj 2.157007 0 Td 30.81438 Tz (- ) Tj 0.246515 0 Td 41.452678 Tz (induced ) Tj 1.879677 0 Td 42.79775 Tz (and ) Tj 0.847395 0 Td 30.81438 Tz (/ ) Tj 0.215701 0 Td 33.382245 Tz (or ) Tj 0.539252 0 Td 38.517975 Tz (disease ) Tj 1.725605 0 Td 30.81438 Tz (- ) Tj 0.154072 0 Td 42.920029 Tz (induced ) Tj 1.925899 0 Td 44.295671 Tz (promoter ) Tj 59.548872 0 0 59.548872 0 1753.05203 Tm 5.424116 0 Td 27.988215 Tz (\( ) Tj 0.201515 0 Td 45.642321 Tz (corresponding ) Tj 3.795202 0 Td 36.38468 Tz (to ) Tj 0.671717 0 Td 39.183502 Tz (the ) Tj 0.940404 0 Td 47.579966 Tz (sequence ) Tj 2.485354 0 Td 47.579966 Tz (encoding ) Tj 2.485354 0 Td 41.049383 Tz (the ) Tj 0.97399 0 Td 46.647026 Tz (second ) Tj 1.931187 0 Td 44.781145 Tz (agglu- ) Tj 2.871591 0 Td 47.579966 Tz (can ) Tj 1.074747 0 Td 47.579966 Tz (be ) Tj 0.806061 0 Td 48.279672 Tz (used ) Tj 1.360227 0 Td 37.784091 Tz (to ) Tj 0.705303 0 Td 49.579125 Tz (promote ) Tj 2.317424 0 Td 43.381734 Tz (elevated ) Tj 2.317424 0 Td 44.501263 Tz (expression ) Tj 2.905177 0 Td 39.183502 Tz (in ) Tj 0.671717 0 Td 45.830703 Tz (response ) Tj 2.418182 0 Td 37.784091 Tz (to ) Tj 62.857143 0 0 62.857143 0 1708.143481 Tm 5.122727 0 Td 36.590909 Tz (tinin ) Tj 1.336364 0 Td 42.424242 Tz (superfamily ) Tj 3.038636 0 Td 44.486532 Tz (conserved ) Tj 2.625 0 Td 49.05303 Tz (domain ) Tj 1.797727 0 Td 13.257576 Tz (, ) Tj 0.35 0 Td 27.840909 Tz (i.e. ) Tj 0.731818 0 Td 13.257576 Tz (, ) Tj 0.334091 0 Td 41.893939 Tz (bases ) Tj 1.511364 0 Td 47.138047 Tz (2330-2734 ) Tj 2.943182 0 Td 35.795455 Tz (30 ) Tj 0.843182 0 Td 44.081439 Tz (exposure ) Tj 2.338636 0 Td 35.795455 Tz (to ) Tj 0.684091 0 Td 39.772727 Tz (a ) Tj 0.445455 0 Td 45.738636 Tz (pathogen ) Tj 2.418182 0 Td 39.772727 Tz (or ) Tj 0.7 0 Td 39.015152 Tz (disease ) Tj 1.734091 0 Td 18.560606 Tz (. ) Tj 0.334091 0 Td 48.058712 Tz (Examples ) Tj 2.545455 0 Td 45.075758 Tz (of ) Tj 0.763636 0 Td 48.390152 Tz (pathogen ) Tj 59.689441 0 0 59.689441 0 1666.377636 Tm 5.411342 0 Td 47.467915 Tz (of ) Tj 0.753902 0 Td 63.290554 Tz (SEQ ) Tj 1.373777 0 Td 53.052376 Tz (ID ) Tj 0.871176 0 Td 73.994103 Tz (NO ) Tj 0.954943 0 Td 11.168921 Tz (: ) Tj 0.184287 0 Td 27.922303 Tz (1 ) Tj 0.284807 0 Td 13.961152 Tz (, ) Tj 0.335068 0 Td 51.377038 Tz (which ) Tj 1.759105 0 Td 30.714533 Tz (is ) Tj 0.636629 0 Td 43.000347 Tz (equivalent ) Tj 2.797815 0 Td 39.091224 Tz (to ) Tj 0.703642 0 Td 44.675685 Tz (bases ) Tj 1.608325 0 Td 47.467915 Tz (511-915 ) Tj 2.261707 0 Td 47.467915 Tz (of ) Tj 1.792612 0 Td 47.069025 Tz (induced ) Tj 2.094173 0 Td 46.84742 Tz (promoters ) Tj 2.697294 0 Td 43.479015 Tz (include ) Tj 1.960146 0 Td 41.883455 Tz (the ) Tj 0.904683 0 Td 45.722771 Tz (pathogen ) Tj 2.395734 0 Td 27.922303 Tz (- ) Tj 0.234547 0 Td 44.276795 Tz (induced ) Tj 2.010406 0 Td 55.844606 Tz (PRP1 ) Tj 1.574818 0 Td 48.165973 Tz (gene ) Tj 59.89418 0 0 59.89418 0 1623.594203 Tm 5.409541 0 Td 63.074205 Tz (SEQ ) Tj 1.352385 0 Td 52.871025 Tz (ID ) Tj 0.851502 0 Td 73.741166 Tz (NO ) Tj 0.951678 0 Td 11.130742 Tz (: ) Tj 0.133569 0 Td 44.522968 Tz (2 ) Tj 0.317226 0 Td 27.826855 Tz (\) ) Tj 0.217049 0 Td 13.913428 Tz (, ) Tj 0.333922 0 Td 48.233216 Tz (and ) Tj 0.951678 0 Td 22.261484 Tz (/ ) Tj 0.166961 0 Td 38.957597 Tz (or ) Tj 0.701237 0 Td 62.146643 Tz (SEQ ) Tj 1.352385 0 Td 51.479682 Tz (ID ) Tj 0.834806 0 Td 73.741166 Tz (NO ) Tj 0.951678 0 Td 11.130742 Tz (: ) Tj 0.166961 0 Td 41.740283 Tz (6 ) Tj 0.484187 0 Td 45.379179 Tz (corresponding ) Tj 3.756625 0 Td 37.566254 Tz (to ) Tj 0.684541 0 Td 41.740283 Tz (the ) Tj 2.003534 0 Td 48.001325 Tz (promoter ) Tj 2.554505 0 Td 49.160777 Tz (and ) Tj 1.11864 0 Td 41.740283 Tz (the ) Tj 1.035159 0 Td 42.358657 Tz (inducible ) Tj 2.537809 0 Td 48.001325 Tz (promoter ) Tj 2.554505 0 Td 39.885159 Tz (for ) Tj 0.951678 0 Td 42.667845 Tz (the ) Tj 1.018463 0 Td 49.531802 Tz (maize ) Tj 1.753092 0 Td 60.52341 Tz (PRms ) Tj 62.016807 0 0 62.016807 0 1584.08461 Tm 5.208266 0 Td 45.35061 Tz (sequence ) Tj 2.402575 0 Td 45.35061 Tz (encoding ) Tj 2.402575 0 Td 40.311653 Tz (the ) Tj 0.951355 0 Td 58.227943 Tz (ETX ) Tj 1.225474 0 Td 21.499548 Tz (/ ) Tj 0.016125 0 Td 70.545393 Tz (MTX2 ) Tj 1.951084 0 Td 42.754784 Tz (superfamily ) Tj 3.07981 0 Td 45.089331 Tz (conserved ) Tj 3.660298 0 Td 47.030262 Tz (gene ) Tj 1.144851 0 Td 18.812105 Tz (, ) Tj 0.596612 0 Td 50.523939 Tz (whose ) Tj 1.999458 0 Td 42.461608 Tz (expression ) Tj 3.047561 0 Td 29.561879 Tz (is ) Tj 0.854607 0 Td 44.918699 Tz (induced ) Tj 2.38645 0 Td 45.68654 Tz (by ) Tj 1.031978 0 Td 40.311653 Tz (the ) Tj 1.193225 0 Td 45.35061 Tz (pathogen ) Tj 56.190476 0 0 56.190476 0 1539.952292 Tm 5.748305 0 Td 55.367232 Tz (domain ) Tj 2.011017 0 Td 14.830508 Tz (, ) Tj 0.409322 0 Td 31.144068 Tz (i.e. ) Tj 0.836441 0 Td 14.830508 Tz (, ) Tj 0.373729 0 Td 47.457627 Tz (bases ) Tj 1.726271 0 Td 52.071563 Tz (2816-3103 ) Tj 3.132203 0 Td 50.423729 Tz (of ) Tj 0.818644 0 Td 67.231638 Tz (SEQ ) Tj 1.494915 0 Td 56.355932 Tz (ID ) Tj 0.94322 0 Td 78.601695 Tz (NO ) Tj 1.014407 0 Td 11.864407 Tz (: ) Tj 0.195763 0 Td 29.661017 Tz (1 ) Tj 0.302542 0 Td 14.830508 Tz (, ) Tj 0.391525 0 Td 53.983051 Tz (which ) Tj 1.886441 0 Td 34.110169 Tz (is ) Tj 1.744068 0 Td 53.760593 Tz (Fusarium ) Tj 2.847458 0 Td 50.154083 Tz (moniliforme ) Tj 3.167797 0 Td 29.661017 Tz (. ) Tj 60 0 0 60 0 1497.217806 Tm 5.383333 0 Td 43.055556 Tz (equivalent ) Tj 2.783333 0 Td 38.888889 Tz (to ) Tj 0.7 0 Td 43.888889 Tz (bases ) Tj 1.583333 0 Td 48.611111 Tz (997-1284 ) Tj 2.583333 0 Td 47.222222 Tz (of ) Tj 0.75 0 Td 62.962963 Tz (SEQ ) Tj 1.366667 0 Td 52.777778 Tz (ID ) Tj 0.85 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.133333 0 Td 44.444444 Tz (2 ) Tj 0.316667 0 Td 27.777778 Tz (\) ) Tj 0.25 0 Td 11.111111 Tz (. ) Tj 55.714286 0 0 55.714286 0 1500.402235 Tm 23.94359 0 Td 46.367521 Tz (In ) Tj 0.987179 0 Td 56.837607 Tz (some ) Tj 1.794872 0 Td 54.390054 Tz (embodiments ) Tj 3.571795 0 Td 26.923077 Tz (, ) Tj 0.610256 0 Td 44.871795 Tz (the ) Tj 1.238462 0 Td 46.533713 Tz (invention ) Tj 2.925641 0 Td 47.489316 Tz (provides ) Tj 2.710256 0 Td 43.874644 Tz (plants ) Tj 62.857143 0 0 62.857143 0 1456.47335 Tm 5.743182 0 Td 39.772727 Tz (In ) Tj 0.811364 0 Td 50.378788 Tz (some ) Tj 1.543182 0 Td 48.450413 Tz (embodiments ) Tj 3.181818 0 Td 23.863636 Tz (, ) Tj 0.461364 0 Td 40.656566 Tz (the ) Tj 1.05 0 Td 41.540404 Tz (invention ) Tj 2.545455 0 Td 42.092803 Tz (provides ) Tj 2.354545 0 Td 40.530303 Tz (nucleic ) Tj 2.927273 0 Td 44.633838 Tz (having ) Tj 1.781818 0 Td 47.064394 Tz (improved ) Tj 2.418182 0 Td 40.151515 Tz (disease ) Tj 1.845455 0 Td 39.507576 Tz (resistance ) Tj 2.370455 0 Td 18.560606 Tz (. ) Tj 0.286364 0 Td 48.058712 Tz (Improved ) Tj 2.45 0 Td 40.530303 Tz (disease ) Tj 1.845455 0 Td 43.484848 Tz (resis ) Tj 57.142857 0 0 57.142857 0 1416.268326 Tm 5.6525 0 Td 43.166667 Tz (acids ) Tj 1.715 0 Td 40.833333 Tz (that ) Tj 1.4 0 Td 50.555556 Tz (encode ) Tj 2.24 0 Td 50.555556 Tz (one ) Tj 1.33 0 Td 45.208333 Tz (or ) Tj 0.9275 0 Td 55.416667 Tz (more ) Tj 1.75 0 Td 49.583333 Tz (of ) Tj 0.91 0 Td 43.75 Tz (the ) Tj 1.19 0 Td 43.385417 Tz (proteins ) Tj 2.52 0 Td 49.583333 Tz (of ) Tj 0.9275 0 Td 43.75 Tz (the ) Tj 2.1175 0 Td 45.5 Tz (tance ) Tj 1.6275 0 Td 49.583333 Tz (can ) Tj 1.12 0 Td 51.041667 Tz (be ) Tj 0.875 0 Td 45.9375 Tz (assessed ) Tj 2.4325 0 Td 53.958333 Tz (by ) Tj 0.91 0 Td 50.75 Tz (comparison ) Tj 3.2725 0 Td 48.854167 Tz (with ) Tj 1.4175 0 Td 43.75 Tz (a ) Tj 0.525 0 Td 42.916667 Tz (control ) Tj 2.065 0 Td 46.666667 Tz (plant ) Tj 1.3125 0 Td 29.166667 Tz (, ) Tj 58.571429 0 0 58.571429 0 1373.216061 Tm 5.514634 0 Td 42.999097 Tz (invention ) Tj 2.356098 0 Td 25.609756 Tz (, ) Tj 0.409756 0 Td 41.260163 Tz (as ) Tj 0.734146 0 Td 44.896116 Tz (described ) Tj 2.629268 0 Td 50.081301 Tz (above ) Tj 1.570732 0 Td 11.382114 Tz (. ) Tj 0.307317 0 Td 44.105691 Tz (In ) Tj 0.734146 0 Td 41.056911 Tz (certain ) Tj 1.912195 0 Td 43.631436 Tz (preferred ) Tj 2.595122 0 Td 48.780488 Tz (embodi- ) Tj 3.363415 0 Td 49.186992 Tz (wherein ) Tj 2.287805 0 Td 42.682927 Tz (the ) Tj 1.02439 0 Td 43.495935 Tz (disease ) Tj 2.065854 0 Td 41.544715 Tz (resistance ) Tj 2.765854 0 Td 46.95122 Tz (of ) Tj 0.734146 0 Td 42.682927 Tz (the ) Tj 1.02439 0 Td 42.276423 Tz (control ) Tj 2.031707 0 Td 42.113821 Tz (plant ) Tj 1.502439 0 Td 45.528455 Tz (has ) Tj 1.07561 0 Td 45.528455 Tz (not ) Tj 61.680672 0 0 61.680672 0 1333.55023 Tm 5.220436 0 Td 48.637602 Tz (ments ) Tj 1.442916 0 Td 21.616712 Tz (, ) Tj 0.697139 0 Td 40.531335 Tz (the ) Tj 1.28079 0 Td 42.332728 Tz (invention ) Tj 2.804768 0 Td 43.233424 Tz (provides ) Tj 2.642643 0 Td 39.180291 Tz (isolated ) Tj 2.399455 0 Td 41.303361 Tz (nucleic ) Tj 2.30218 0 Td 41.88238 Tz (acid ) Tj 2.221117 0 Td 47.96208 Tz (been ) Tj 1.28079 0 Td 44.92223 Tz (modified ) Tj 2.30218 0 Td 41.88238 Tz (or ) Tj 0.648501 0 Td 48.299841 Tz (improved ) Tj 2.448093 0 Td 48.637602 Tz (by ) Tj 0.729564 0 Td 48.637602 Tz (methods ) Tj 2.221117 0 Td 40.531335 Tz (or ) Tj 0.616076 0 Td 41.544619 Tz (reagents ) Tj 2.156267 0 Td 44.92223 Tz (provided ) Tj 67.142857 0 0 67.142857 0 1291.925697 Tm 4.825532 0 Td 40.819543 Tz (sequences ) Tj 2.531915 0 Td 42.198582 Tz (encoding ) Tj 2.338298 0 Td 37.234043 Tz (a ) Tj 0.521277 0 Td 37.588652 Tz (protein ) Tj 1.876596 0 Td 41.702128 Tz (comprising ) Tj 2.457447 0 Td 24.822695 Tz (, ) Tj 0.491489 0 Td 37.234043 Tz (consisting ) Tj 2.26383 0 Td 12.411348 Tz (, ) Tj 0.417021 0 Td 38.475177 Tz (or ) Tj 0.789362 0 Td 34.751773 Tz (40 ) Tj 0.789362 0 Td 45.921986 Tz (by ) Tj 0.670213 0 Td 38.652482 Tz (various ) Tj 1.787234 0 Td 37.234043 Tz (aspects ) Tj 1.72766 0 Td 40.957447 Tz (of ) Tj 0.565957 0 Td 37.234043 Tz (the ) Tj 0.804255 0 Td 37.943262 Tz (present ) Tj 1.742553 0 Td 38.061466 Tz (invention ) Tj 2.114894 0 Td 17.375887 Tz (. ) Tj 0.238298 0 Td 38.475177 Tz (In ) Tj 0.595745 0 Td 47.783688 Tz (some ) Tj 1.265957 0 Td 53.368794 Tz (embodi ) Tj 60.879121 0 0 60.879121 0 1250.781489 Tm 5.272744 0 Td 41.612515 Tz (consisting ) Tj 2.825271 0 Td 38.825074 Tz (essentially ) Tj 2.890975 0 Td 49.277978 Tz (of ) Tj 0.854152 0 Td 62.053751 Tz (SEQ ) Tj 1.478339 0 Td 52.015644 Tz (ID ) Tj 0.969134 0 Td 58.859807 Tz (NO ) Tj 0.936282 0 Td 27.376655 Tz (: ) Tj 0.197112 0 Td 27.376655 Tz (3 ) Tj 0.16426 0 Td 27.376655 Tz (, ) Tj 0.525632 0 Td 38.327316 Tz (7 ) Tj 0.32852 0 Td 10.950662 Tz (, ) Tj 0.427076 0 Td 43.802647 Tz (8 ) Tj 0.624188 0 Td 43.802647 Tz (or ) Tj 0.936282 0 Td 35.589651 Tz (9. ) Tj 0.640614 0 Td 52.928199 Tz (The ) Tj 2.217509 0 Td 48.182912 Tz (ments ) Tj 1.708303 0 Td 46.540313 Tz (of ) Tj 0.722744 0 Td 41.064982 Tz (the ) Tj 0.98556 0 Td 41.064982 Tz (invention ) Tj 2.316065 0 Td 24.638989 Tz (, ) Tj 0.361372 0 Td 41.064982 Tz (the ) Tj 0.969134 0 Td 41.064982 Tz (plant ) Tj 1.478339 0 Td 30.11432 Tz (is ) Tj 0.624188 0 Td 41.064982 Tz (a ) Tj 0.49278 0 Td 40.567225 Tz (genetically ) Tj 2.907401 0 Td 45.513688 Tz (modified ) Tj 60.952381 0 0 60.952381 0 1208.660659 Tm 5.299219 0 Td 42.838542 Tz (invention ) Tj 2.526562 0 Td 39.648438 Tz (also ) Tj 1.18125 0 Td 43.408203 Tz (provides ) Tj 2.329687 0 Td 44.661458 Tz (fragments ) Tj 2.657812 0 Td 49.21875 Tz (and ) Tj 1.099219 0 Td 48.97017 Tz (complements ) Tj 3.478125 0 Td 46.484375 Tz (of ) Tj 0.705469 0 Td 41.015625 Tz (the ) Tj 1.985156 0 Td 40.46875 Tz (plant ) Tj 1.394531 0 Td 37.597656 Tz (that ) Tj 1.066406 0 Td 44.661458 Tz (has ) Tj 0.984375 0 Td 48.535156 Tz (been ) Tj 1.328906 0 Td 39.453125 Tz (altered ) Tj 1.821094 0 Td 50.585938 Tz (by ) Tj 0.771094 0 Td 41.015625 Tz (the ) Tj 0.935156 0 Td 41.471354 Tz (introduction ) Tj 3.15 0 Td 46.484375 Tz (of ) Tj 0.672656 0 Td 48.003472 Tz (exogenous ) Tj 58.345865 0 0 58.345865 0 1167.129243 Tm 5.518814 0 Td 43.664089 Tz (nucleic ) Tj 2.125258 0 Td 42.847938 Tz (acids ) Tj 1.593943 0 Td 45.069683 Tz (described ) Tj 2.70799 0 Td 46.974036 Tz (elsewhere ) Tj 2.810825 0 Td 41.419674 Tz (herein ) Tj 1.576804 0 Td 25.708763 Tz (, ) Tj 0.462758 0 Td 41.419674 Tz (as ) Tj 0.788402 0 Td 44.990335 Tz (well ) Tj 1.371134 0 Td 41.419674 Tz (as ) Tj 0.874098 0 Td 44.990335 Tz (non- ) Tj 2.382345 0 Td 43.256014 Tz (nucleic ) Tj 2.108119 0 Td 43.56207 Tz (acid ) Tj 1.302577 0 Td 48.20393 Tz (encoding ) Tj 2.588015 0 Td 42.847938 Tz (a ) Tj 0.497036 0 Td 43.664089 Tz (protein ) Tj 2.07384 0 Td 46.112543 Tz (capable ) Tj 2.193814 0 Td 48.560997 Tz (of ) Tj 0.771263 0 Td 44.276203 Tz (conferring ) Tj 2.982216 0 Td 51.417526 Tz (dis ) Tj 63.428571 0 0 63.428571 0 1122.998135 Tm 5.092342 0 Td 37.078745 Tz (identical ) Tj 2.191441 0 Td 41.166166 Tz (but ) Tj 0.93018 0 Td 48.085586 Tz (homologous ) Tj 3.09009 0 Td 39.78979 Tz (nucleic ) Tj 1.891892 0 Td 40.728228 Tz (acid ) Tj 1.166667 0 Td 43.793794 Tz (sequences ) Tj 2.380631 0 Td 18.393393 Tz (, ) Tj 0.315315 0 Td 33.502252 Tz (e.g. ) Tj 0.867117 0 Td 13.138138 Tz (, ) Tj 0.394144 0 Td 38.100601 Tz (sub- ) Tj 2.128378 0 Td 41.385135 Tz (ease ) Tj 1.182432 0 Td 38.626126 Tz (resistance ) Tj 2.317568 0 Td 18.393393 Tz (. ) Tj 0.346847 0 Td 39.414414 Tz (In ) Tj 0.646396 0 Td 40.29029 Tz (preferred ) Tj 2.364865 0 Td 47.536173 Tz (embodiments ) Tj 3.358108 0 Td 44.66967 Tz (of ) Tj 0.646396 0 Td 40.29029 Tz (the ) Tj 0.914414 0 Td 40.874208 Tz (invention ) Tj 2.207207 0 Td 23.648649 Tz (, ) Tj 61.428571 0 0 61.428571 0 1084.28633 Tm 5.274419 0 Td 36.627907 Tz (stantially ) Tj 2.474419 0 Td 37.984496 Tz (identical ) Tj 2.360465 0 Td 44.918174 Tz (sequences ) Tj 2.44186 0 Td 18.992248 Tz (. ) Tj 0.406977 0 Td 45.219638 Tz (Unless ) Tj 1.92093 0 Td 43.410853 Tz (otherwise ) Tj 2.62093 0 Td 38.888889 Tz (indicated ) Tj 2.213953 0 Td 24.418605 Tz (, ) Tj 0.52093 0 Td 36.627907 Tz (45 ) Tj 0.862791 0 Td 40.697674 Tz (the ) Tj 0.960465 0 Td 47.329888 Tz (exogenous ) Tj 2.783721 0 Td 41.085271 Tz (nucleic ) Tj 1.969767 0 Td 41.375969 Tz (acid ) Tj 1.204651 0 Td 45.822567 Tz (comprises ) Tj 2.393023 0 Td 27.131783 Tz (, ) Tj 0.423256 0 Td 39.341085 Tz (consists ) Tj 1.937209 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 40.697674 Tz (or ) Tj 0.7 0 Td 39.341085 Tz (consists ) Tj 61.428571 0 0 61.428571 0 1042.416722 Tm 5.225581 0 Td 41.903531 Tz (reference ) Tj 2.539535 0 Td 35.271318 Tz (to ) Tj 0.7 0 Td 40.697674 Tz (a ) Tj 0.504651 0 Td 40.697674 Tz (nucleic ) Tj 1.986047 0 Td 42.054264 Tz (acid ) Tj 1.269767 0 Td 45.784884 Tz (sequence ) Tj 2.45814 0 Td 38.662791 Tz (also ) Tj 1.204651 0 Td 47.603946 Tz (encompasses ) Tj 3.434884 0 Td 28.940568 Tz (its ) Tj 1.790698 0 Td 38.477801 Tz (essentially ) Tj 2.897674 0 Td 44.767442 Tz (of ) Tj 0.813953 0 Td 47.932817 Tz (one ) Tj 1.204651 0 Td 46.124031 Tz (of ) Tj 0.813953 0 Td 40.697674 Tz (the ) Tj 1.05814 0 Td 41.472868 Tz (nucleic ) Tj 2.1 0 Td 40.155039 Tz (acids ) Tj 1.562791 0 Td 45.106589 Tz (provided ) Tj 2.474419 0 Td 39.341085 Tz (herein ) Tj 1.530233 0 Td 24.418605 Tz (, ) Tj 59.863946 0 0 59.863946 0 1001.978157 Tm 5.378864 0 Td 52.897727 Tz (complement ) Tj 3.023523 0 Td 27.840909 Tz (. ) Tj 0.484432 0 Td 50.809659 Tz (Such ) Tj 1.503409 0 Td 45.782828 Tz (sequences ) Tj 2.739545 0 Td 40.214646 Tz (typically ) Tj 2.472273 0 Td 42.318182 Tz (share ) Tj 1.553523 0 Td 34.801136 Tz (at ) Tj 0.684886 0 Td 37.863636 Tz (least ) Tj 1.419886 0 Td 44.545455 Tz (65 ) Tj 0.601364 0 Td 80.738636 Tz (% ) Tj 1.804091 0 Td 44.545455 Tz (and ) Tj 0.935455 0 Td 19.488636 Tz (/ ) Tj 0.167045 0 Td 40.369318 Tz (or ) Tj 0.701591 0 Td 46.931818 Tz (encodes ) Tj 2.221705 0 Td 48.257576 Tz (one ) Tj 1.1025 0 Td 47.329545 Tz (of ) Tj 0.718295 0 Td 41.761364 Tz (the ) Tj 0.968864 0 Td 41.413352 Tz (proteins ) Tj 2.221705 0 Td 46.633523 Tz (provided ) Tj 2.438864 0 Td 42.225379 Tz (herein ) Tj 1.603636 0 Td 19.488636 Tz (. ) Tj 62.517007 0 0 62.517007 0 958.422348 Tm 5.18259 0 Td 44.987758 Tz (sequence ) Tj 2.303373 0 Td 37.323177 Tz (identity ) Tj 1.935473 0 Td 43.98803 Tz (with ) Tj 1.215669 0 Td 43.839923 Tz (sequences ) Tj 2.527312 0 Td 40.877766 Tz (disclosed ) Tj 2.335365 0 Td 40.877766 Tz (herein ) Tj 1.455604 0 Td 23.993471 Tz (, ) Tj 0.319913 0 Td 41.470197 Tz (including ) Tj 4.046899 0 Td 50.652884 Tz (The ) Tj 1.087704 0 Td 45.321001 Tz (term ) Tj 1.263656 0 Td 15.995647 Tz ( ) Tj 0.143961 0 Td 51.541531 Tz (exogenous ) Tj 2.83123 0 Td 15.995647 Tz ( ) Tj 0.271926 0 Td 30.658324 Tz (is ) Tj 0.543852 0 Td 45.987486 Tz (used ) Tj 1.263656 0 Td 41.766413 Tz (herein ) Tj 1.663547 0 Td 35.990207 Tz (to ) Tj 0.62383 0 Td 37.856366 Tz (refer ) Tj 1.279652 0 Td 37.323177 Tz (to ) Tj 0.639826 0 Td 39.989119 Tz (a ) Tj 0.415887 0 Td 40.369967 Tz (nucleic ) Tj 63.526786 0 0 63.526786 0 916.581119 Tm 5.100211 0 Td 59.467479 Tz (SEQ ) Tj 1.275053 0 Td 48.535957 Tz (ID ) Tj 0.771328 0 Td 69.524479 Tz (NO ) Tj 0.897259 0 Td 10.494261 Tz (: ) Tj 0.362052 0 Td 26.235652 Tz (1 ) Tj 0.251862 0 Td 13.117826 Tz (, ) Tj 0.314828 0 Td 41.977044 Tz (2 ) Tj 0.299086 0 Td 13.117826 Tz (, ) Tj 0.314828 0 Td 41.977044 Tz (4 ) Tj 0.299086 0 Td 13.117826 Tz (, ) Tj 0.314828 0 Td 39.353479 Tz (or ) Tj 0.67688 0 Td 36.729913 Tz (5 ) Tj 0.299086 0 Td 13.117826 Tz (, ) Tj 0.283345 0 Td 39.728274 Tz (nucleic ) Tj 1.888967 0 Td 40.665261 Tz (acid ) Tj 1.164863 0 Td 43.143073 Tz (sequences ) Tj 2.550105 0 Td 44.272663 Tz (encoding ) Tj 3.352916 0 Td 40.665261 Tz (acid ) Tj 1.306535 0 Td 44.272663 Tz (sequence ) Tj 2.471398 0 Td 26.235652 Tz (\( ) Tj 0.173155 0 Td 33.450457 Tz (e.g. ) Tj 0.865777 0 Td 13.117826 Tz (, ) Tj 0.4565 0 Td 64.714609 Tz (DNA ) Tj 1.227829 0 Td 23.612087 Tz (, ) Tj 0.503725 0 Td 62.965566 Tz (RNA ) Tj 1.275053 0 Td 26.235652 Tz (\) ) Tj 0.125931 0 Td 26.235652 Tz (, ) Tj 0.487983 0 Td 47.880066 Tz (gene ) Tj 1.117639 0 Td 18.364957 Tz (, ) Tj 0.4565 0 Td 40.665261 Tz (or ) Tj 0.78707 0 Td 39.728274 Tz (protein ) Tj 1.983415 0 Td 36.729913 Tz (that ) Tj 67.142857 0 0 67.142857 0 876.035648 Tm 4.810638 0 Td 37.234043 Tz (a ) Tj 0.37234 0 Td 37.588652 Tz (protein ) Tj 1.72766 0 Td 41.702128 Tz (comprising ) Tj 2.457447 0 Td 24.822695 Tz (, ) Tj 0.32766 0 Td 37.234043 Tz (consisting ) Tj 2.278723 0 Td 12.411348 Tz (, ) Tj 0.268085 0 Td 37.234043 Tz (or ) Tj 0.595745 0 Td 37.234043 Tz (consisting ) Tj 2.397872 0 Td 35.203095 Tz (essentially ) Tj 2.487234 0 Td 42.198582 Tz (of ) Tj 0.804255 0 Td 33.510638 Tz (50 ) Tj 0.789362 0 Td 35.992908 Tz (originates ) Tj 2.338298 0 Td 44.680851 Tz (from ) Tj 1.23617 0 Td 37.234043 Tz (a ) Tj 0.417021 0 Td 39.3026 Tz (source ) Tj 1.578723 0 Td 37.943262 Tz (outside ) Tj 1.757447 0 Td 42.198582 Tz (of ) Tj 0.625532 0 Td 24.822695 Tz (\( ) Tj 0.178723 0 Td 26.06383 Tz (i.e. ) Tj 0.685106 0 Td 12.411348 Tz (, ) Tj 0.282979 0 Td 37.943262 Tz (foreign ) Tj 1.742553 0 Td 33.510638 Tz (to ) Tj 0.446809 0 Td 24.822695 Tz (\) ) Tj 0.312766 0 Td 37.234043 Tz (the ) Tj 0.834043 0 Td 38.475177 Tz (host ) Tj 61.216931 0 0 61.216931 0 832.606207 Tm 5.292653 0 Td 61.711322 Tz (SEQ ) Tj 1.339499 0 Td 51.728608 Tz (ID ) Tj 0.833103 0 Td 72.147796 Tz (NO ) Tj 0.931115 0 Td 10.890233 Tz (: ) Tj 0.343042 0 Td 40.838375 Tz (3 ) Tj 0.310372 0 Td 13.612792 Tz (, ) Tj 0.359378 0 Td 40.838375 Tz (6 ) Tj 0.310372 0 Td 13.612792 Tz (, ) Tj 0.343042 0 Td 40.838375 Tz (or ) Tj 0.70242 0 Td 34.031979 Tz (7. ) Tj 0.669749 0 Td 53.770527 Tz (More ) Tj 1.502852 0 Td 41.110631 Tz (preferably ) Tj 2.417632 0 Td 27.225583 Tz (, ) Tj 0.424719 0 Td 40.838375 Tz (a ) Tj 0.45739 0 Td 41.227312 Tz (nucleic ) Tj 1.976577 0 Td 42.199654 Tz (acid ) Tj 1.225151 0 Td 46.283492 Tz (of ) Tj 1.731547 0 Td 40.293863 Tz (plant ) Tj 1.519188 0 Td 37.435177 Tz (into ) Tj 1.192481 0 Td 50.095073 Tz (which ) Tj 1.780553 0 Td 27.225583 Tz (it ) Tj 0.620743 0 Td 29.948142 Tz (is ) Tj 0.686085 0 Td 43.016422 Tz (introduced ) Tj 2.858686 0 Td 38.115817 Tz (to ) Tj 0.767761 0 Td 39.930856 Tz (create ) Tj 1.715212 0 Td 40.838375 Tz (the ) Tj 1.012792 0 Td 41.655143 Tz (transgenic ) Tj 56.483516 0 0 56.483516 0 793.326389 Tm 5.700778 0 Td 44.2607 Tz (the ) Tj 1.133074 0 Td 46.227843 Tz (invention ) Tj 2.832685 0 Td 44.2607 Tz (shares ) Tj 1.947471 0 Td 36.883917 Tz (at ) Tj 0.778988 0 Td 39.539559 Tz (least ) Tj 1.522568 0 Td 48.68677 Tz (75 ) Tj 0.655058 0 Td 85.570687 Tz (% ) Tj 0.86751 0 Td 40.20347 Tz (identity ) Tj 1.894358 0 Td 29.507134 Tz (, ) Tj 0.566537 0 Td 31.277562 Tz (still ) Tj 1.274708 0 Td 56.063554 Tz (more ) Tj 1.681907 0 Td 42.293558 Tz (for ) Tj 2.071401 0 Td 45.440986 Tz (plant ) Tj 1.274708 0 Td 29.507134 Tz (. ) Tj 0.49572 0 Td 51.145698 Tz (For ) Tj 1.203891 0 Td 51.848249 Tz (example ) Tj 2.213035 0 Td 29.507134 Tz (, ) Tj 0.442607 0 Td 44.2607 Tz (the ) Tj 1.079961 0 Td 50.899805 Tz (term ) Tj 1.504864 0 Td 42.785344 Tz (as ) Tj 0.832101 0 Td 28.031777 Tz (it ) Tj 0.637354 0 Td 32.457847 Tz (is ) Tj 0.690467 0 Td 50.899805 Tz (used ) Tj 1.504864 0 Td 42.785344 Tz (in ) Tj 0.778988 0 Td 45.244272 Tz (reference ) Tj 2.726459 0 Td 39.83463 Tz (to ) Tj 58.423645 0 0 58.423645 0 751.136334 Tm 5.511467 0 Td 43.646712 Tz (preferably ) Tj 2.824199 0 Td 37.085441 Tz (at ) Tj 0.650422 0 Td 38.226532 Tz (least ) Tj 1.369309 0 Td 48.496346 Tz (80 ) Tj 0.616189 0 Td 82.729061 Tz (% ) Tj 0.547723 0 Td 14.263631 Tz (, ) Tj 0.342327 0 Td 47.069983 Tz (85 ) Tj 0.633305 0 Td 82.729061 Tz (% ) Tj 0.547723 0 Td 14.263631 Tz (, ) Tj 0.325211 0 Td 49.922709 Tz (90 ) Tj 0.633305 0 Td 82.729061 Tz (% ) Tj 0.547723 0 Td 14.263631 Tz (, ) Tj 0.325211 0 Td 44.217257 Tz (or ) Tj 0.718887 0 Td 47.069983 Tz (95 ) Tj 0.633305 0 Td 82.729061 Tz (% ) Tj 0.547723 0 Td 14.263631 Tz (, ) Tj 0.325211 0 Td 50.398164 Tz (and ) Tj 1.095447 0 Td 49.922709 Tz (even ) Tj 1.369309 0 Td 54.91498 Tz (more ) Tj 2.618803 0 Td 45.358347 Tz (expression ) Tj 2.96113 0 Td 48.496346 Tz (of ) Tj 0.75312 0 Td 49.922709 Tz (an ) Tj 0.821585 0 Td 48.496346 Tz (encoding ) Tj 2.550337 0 Td 43.605958 Tz (nucleic ) Tj 2.088196 0 Td 44.217257 Tz (acid ) Tj 1.095447 0 Td 14.263631 Tz (, ) Tj 0.342327 0 Td 39.938168 Tz (refers ) Tj 1.677403 0 Td 38.511804 Tz (to ) Tj 0.770236 0 Td 48.496346 Tz (introduc ) Tj 60.519481 0 0 60.519481 0 710.64466 Tm 5.320601 0 Td 42.135193 Tz (preferably ) Tj 2.825536 0 Td 34.424177 Tz (at ) Tj 0.710515 0 Td 36.902718 Tz (least ) Tj 1.42103 0 Td 45.439914 Tz (99 ) Tj 0.59485 0 Td 79.864092 Tz (% ) Tj 0.776609 0 Td 38.89932 Tz (identity ) Tj 2.148069 0 Td 45.439914 Tz (with ) Tj 1.371459 0 Td 48.652837 Tz (one ) Tj 1.156652 0 Td 42.68598 Tz (or ) Tj 0.760086 0 Td 53.013233 Tz (more ) Tj 1.553219 0 Td 46.816881 Tz (of ) Tj 0.776609 0 Td 41.309013 Tz (the ) Tj 1.999356 0 Td 39.932046 Tz (tion ) Tj 1.107082 0 Td 46.816881 Tz (of ) Tj 0.660944 0 Td 46.816881 Tz (an ) Tj 0.710515 0 Td 48.346845 Tz (exogenous ) Tj 2.775966 0 Td 46.816881 Tz (encoding ) Tj 2.379399 0 Td 42.095851 Tz (nucleic ) Tj 1.949785 0 Td 41.997496 Tz (acid ) Tj 1.156652 0 Td 39.932046 Tz (in ) Tj 0.611373 0 Td 48.193848 Tz (an ) Tj 0.727039 0 Td 41.809728 Tz (expressible ) Tj 64.285714 0 0 64.285714 0 663.079044 Tm 5.024444 0 Td 43.333333 Tz (aforementioned ) Tj 3.795556 0 Td 39.259259 Tz (nucleic ) Tj 1.851111 0 Td 40.185185 Tz (acid ) Tj 1.135556 0 Td 42.921811 Tz (sequences ) Tj 2.333333 0 Td 18.148148 Tz (. ) Tj 0.311111 0 Td 40.185185 Tz (In ) Tj 0.637778 0 Td 38.111111 Tz (particular ) Tj 2.162222 0 Td 25.925926 Tz (, ) Tj 0.342222 0 Td 46.666667 Tz (minor ) Tj 1.757778 0 Td 33.703704 Tz (55 ) Tj 0.824444 0 Td 46.666667 Tz (form ) Tj 1.306667 0 Td 36.296296 Tz (into ) Tj 1.073333 0 Td 38.888889 Tz (the ) Tj 0.886667 0 Td 40.185185 Tz (host ) Tj 1.135556 0 Td 42 Tz (plant ) Tj 1.135556 0 Td 25.925926 Tz (. ) Tj 0.373333 0 Td 38.888889 Tz (In ) Tj 0.668889 0 Td 39.407407 Tz (other ) Tj 1.353333 0 Td 48.222222 Tz (words ) Tj 1.4 0 Td 23.333333 Tz (, ) Tj 0.342222 0 Td 38.888889 Tz (the ) Tj 0.886667 0 Td 39.259259 Tz (nucleic ) Tj 1.866667 0 Td 40.185185 Tz (acid ) Tj 1.151111 0 Td 29.814815 Tz (is ) Tj 59.371429 0 0 59.371429 0 624.323839 Tm 5.45717 0 Td 40.596234 Tz (substitutions ) Tj 3.115977 0 Td 25.264678 Tz (, ) Tj 0.353705 0 Td 41.795886 Tz (deletions ) Tj 2.223292 0 Td 25.264678 Tz (, ) Tj 0.336862 0 Td 49.593626 Tz (and ) Tj 1.02743 0 Td 42.107796 Tz (the ) Tj 0.909528 0 Td 38.598813 Tz (like ) Tj 1.07796 0 Td 48.657898 Tz (can ) Tj 0.993744 0 Td 49.125762 Tz (be ) Tj 0.741097 0 Td 44.914982 Tz (introduced ) Tj 2.829644 0 Td 36.493423 Tz (at ) Tj 0.589509 0 Td 49.593626 Tz (one ) Tj 2.172762 0 Td 43.979254 Tz (not ) Tj 0.943215 0 Td 42.57566 Tz (native ) Tj 1.684312 0 Td 37.897016 Tz (to ) Tj 0.640038 0 Td 44.914982 Tz (and ) Tj 0.960058 0 Td 19.650305 Tz (/ ) Tj 0.151588 0 Td 40.704203 Tz (or ) Tj 0.623195 0 Td 44.914982 Tz (has ) Tj 0.976901 0 Td 43.979254 Tz (not ) Tj 0.943215 0 Td 49.125762 Tz (been ) Tj 1.330606 0 Td 44.914982 Tz (derived ) Tj 2.038017 0 Td 49.827559 Tz (from ) Tj 1.347449 0 Td 38.598813 Tz (that ) Tj 1.07796 0 Td 40.423484 Tz (particular ) Tj 60 0 0 60 0 585.664958 Tm 5.383333 0 Td 43.055556 Tz (or ) Tj 0.65 0 Td 52.777778 Tz (more ) Tj 1.416667 0 Td 41.358025 Tz (positions ) Tj 2.416667 0 Td 40.277778 Tz (in ) Tj 0.616667 0 Td 41.666667 Tz (the ) Tj 0.916667 0 Td 42.901235 Tz (disclosed ) Tj 2.483333 0 Td 45.679012 Tz (sequences ) Tj 2.633333 0 Td 45.238095 Tz (without ) Tj 2.116667 0 Td 41.269841 Tz (depart- ) Tj 2.95 0 Td 45 Tz (plant ) Tj 1.2 0 Td 27.777778 Tz (. ) Tj 0.516667 0 Td 41.666667 Tz (In ) Tj 0.816667 0 Td 41.319444 Tz (contrast ) Tj 1.966667 0 Td 22.222222 Tz (, ) Tj 0.433333 0 Td 41.666667 Tz (the ) Tj 1.066667 0 Td 47.222222 Tz (term ) Tj 1.5 0 Td 33.333333 Tz (" ) Tj 0.366667 0 Td 47.777778 Tz (endogenous ) Tj 2.85 0 Td 33.333333 Tz ( ) Tj 0.566667 0 Td 30.555556 Tz (is ) Tj 0.683333 0 Td 47.916667 Tz (used ) Tj 1.45 0 Td 43.055556 Tz (herein ) Tj 59.813665 0 0 59.813665 0 543.014735 Tm 5.400104 0 Td 42.72528 Tz (ing ) Tj 1.019834 0 Td 49.459155 Tz (from ) Tj 1.404361 0 Td 41.796469 Tz (the ) Tj 1.019834 0 Td 45.697473 Tz (scope ) Tj 1.621703 0 Td 45.976116 Tz (of ) Tj 0.718899 0 Td 41.796469 Tz (the ) Tj 0.986397 0 Td 43.344487 Tz (invention ) Tj 2.340602 0 Td 25.077882 Tz (, ) Tj 0.417965 0 Td 40.403254 Tz (so ) Tj 0.752336 0 Td 45.279508 Tz (long ) Tj 1.320768 0 Td 40.403254 Tz (as ) Tj 0.718899 0 Td 41.796469 Tz (the ) Tj 0.986397 0 Td 40.602285 Tz (altered ) Tj 2.95919 0 Td 44.025614 Tz (interchangeably ) Tj 4.279958 0 Td 46.672724 Tz (with ) Tj 1.437799 0 Td 27.864313 Tz ( ) Tj 0.250779 0 Td 44.582901 Tz (native ) Tj 1.65514 0 Td 25.077882 Tz ( ) Tj 0.501558 0 Td 49.226953 Tz (and ) Tj 1.18702 0 Td 39.010038 Tz (refers ) Tj 1.738733 0 Td 37.616822 Tz (to ) Tj 0.785774 0 Td 42.592593 Tz (nucleic ) Tj 2.139979 0 Td 43.189685 Tz (acid ) Tj 59.115646 0 0 59.115646 0 504.671494 Tm 5.480783 0 Td 47.576237 Tz (sequence ) Tj 2.554315 0 Td 45.109321 Tz (maintains ) Tj 2.740391 0 Td 40.338143 Tz (functionality ) Tj 3.129459 0 Td 28.193326 Tz (, ) Tj 0.490564 0 Td 35.94649 Tz (e.g. ) Tj 0.93038 0 Td 14.096663 Tz (, ) Tj 0.405984 0 Td 47.928654 Tz (encoding ) Tj 2.588147 0 Td 42.289988 Tz (a ) Tj 0.524396 0 Td 43.095512 Tz (protein ) Tj 3.095627 0 Td 47.928654 Tz (sequences ) Tj 2.537399 0 Td 19.735328 Tz (, ) Tj 0.524396 0 Td 48.49252 Tz (genes ) Tj 1.43786 0 Td 19.735328 Tz (, ) Tj 0.524396 0 Td 48.633487 Tz (gene ) Tj 1.539356 0 Td 44.052071 Tz (products ) Tj 2.148331 0 Td 28.193326 Tz (, ) Tj 0.558228 0 Td 41.937572 Tz (proteins ) Tj 2.063751 0 Td 14.096663 Tz (, ) Tj 0.50748 0 Td 34.536824 Tz (etc. ) Tj 1.234868 0 Td 39.470656 Tz (that ) Tj 1.319448 0 Td 41.350211 Tz (are ) Tj 62.857143 0 0 62.857143 0 457.368421 Tm 5.122727 0 Td 44.633838 Tz (having ) Tj 2.004545 0 Td 39.772727 Tz (the ) Tj 1.113636 0 Td 40.530303 Tz (disease ) Tj 2.084091 0 Td 38.977273 Tz (resistance ) Tj 2.752273 0 Td 36.458333 Tz (activity ) Tj 2.163636 0 Td 43.75 Tz (of ) Tj 0.859091 0 Td 39.772727 Tz (the ) Tj 1.097727 0 Td 41.245791 Tz (unaltered ) Tj 2.609091 0 Td 34.469697 Tz (60 ) Tj 0.811364 0 Td 38.888889 Tz (naturally ) Tj 2.306818 0 Td 40.568182 Tz (associated ) Tj 2.609091 0 Td 44.412879 Tz (with ) Tj 1.256818 0 Td 39.772727 Tz (or ) Tj 0.668182 0 Td 46.136364 Tz (found ) Tj 1.559091 0 Td 38.44697 Tz (in ) Tj 0.652273 0 Td 39.772727 Tz (a ) Tj 0.429545 0 Td 39.393939 Tz (control ) Tj 1.861364 0 Td 41.098485 Tz (or ) Tj 0.668182 0 Td 43.087121 Tz (wild ) Tj 1.161364 0 Td 26.515152 Tz (- ) Tj 0.127273 0 Td 41.098485 Tz (type ) Tj 44.285714 0 0 44.285714 0 422.695652 Tm 7.293548 0 Td 61.626344 Tz (sequence ) Tj 3.048387 0 Td 26.344086 Tz (. ) Tj 52.857143 0 0 52.857143 0 427.186047 Tm 24.5 0 Td 47.927928 Tz (plant ) Tj 1.362162 0 Td 31.531532 Tz (. ) Tj 59.126984 0 0 59.126984 0 376.097433 Tm 6.105503 0 Td 52.61745 Tz (The ) Tj 1.251544 0 Td 44.161074 Tz (invention ) Tj 2.672215 0 Td 40.671141 Tz (further ) Tj 1.978792 0 Td 45.100671 Tz (provides ) Tj 2.469262 0 Td 42.684564 Tz (nucleic ) Tj 2.114094 0 Td 43.691275 Tz (acid ) Tj 1.336107 0 Td 41.718121 Tz (constructs ) Tj 2.570738 0 Td 22.550336 Tz (, ) Tj 2.063356 0 Td 43.691275 Tz (In ) Tj 0.710336 0 Td 48.85906 Tz (one ) Tj 1.082416 0 Td 42.281879 Tz (or ) Tj 0.67651 0 Td 53.557047 Tz (more ) Tj 1.488322 0 Td 51.76327 Tz (embodiments ) Tj 3.38255 0 Td 25.369128 Tz (, ) Tj 0.338255 0 Td 42.281879 Tz (the ) Tj 0.964027 0 Td 49.17226 Tz (exogenous ) Tj 2.858255 0 Td 42.684564 Tz (nucleic ) Tj 2.012617 0 Td 42.986577 Tz (acid ) Tj 62.184874 0 0 62.184874 0 334.022124 Tm 5.194189 0 Td 41.691692 Tz (including ) Tj 2.460405 0 Td 40.585586 Tz (vectors ) Tj 1.768919 0 Td 13.400901 Tz (, ) Tj 0.321622 0 Td 43.88795 Tz (plasmids ) Tj 2.363919 0 Td 47.34985 Tz (and ) Tj 1.061351 0 Td 42.614865 Tz (expression ) Tj 2.782027 0 Td 39.309309 Tz (cassettes ) Tj 2.090541 0 Td 21.441441 Tz (, ) Tj 0.385946 0 Td 50.923423 Tz (com- ) Tj 2.428243 0 Td 45.228041 Tz (encoding ) Tj 2.444324 0 Td 40.202703 Tz (the ) Tj 0.997027 0 Td 43.106231 Tz (thermostable ) Tj 3.393108 0 Td 39.309309 Tz (starch ) Tj 1.704595 0 Td 42.212838 Tz (synthase ) Tj 2.299595 0 Td 40.585586 Tz (protein ) Tj 1.977973 0 Td 29.481982 Tz (is ) Tj 0.659324 0 Td 38.192568 Tz (also ) Tj 61.360544 0 0 61.360544 0 293.815503 Tm 5.247672 0 Td 39.966741 Tz (prising ) Tj 1.857871 0 Td 33.952328 Tz (at ) Tj 0.586696 0 Td 36.396896 Tz (least ) Tj 1.254878 0 Td 47.080562 Tz (one ) Tj 1.010421 0 Td 41.13082 Tz (nucleic ) Tj 1.92306 0 Td 41.42184 Tz (acid ) Tj 1.173392 0 Td 45.49612 Tz (sequence ) Tj 2.363082 0 Td 44.817073 Tz (of ) Tj 0.61929 0 Td 41.648189 Tz (the ) Tj 0.912639 0 Td 42.553585 Tz (invention ) Tj 2.444568 0 Td 39.384701 Tz (as ) Tj 1.727494 0 Td 43.685329 Tz (heterologous ) Tj 3.096452 0 Td 27.161863 Tz (. ) Tj 0.537805 0 Td 51.607539 Tz (The ) Tj 1.254878 0 Td 46.854213 Tz (term ) Tj 1.466741 0 Td 16.297118 Tz (" ) Tj 0.146674 0 Td 46.854213 Tz (heterologous ) Tj 3.422395 0 Td 16.297118 Tz ( ) Tj 0.440022 0 Td 37.57391 Tz (refers ) Tj 1.711197 0 Td 36.668514 Tz (to ) Tj 0.814856 0 Td 41.13082 Tz (genetic ) Tj 60 0 0 60 0 249.779886 Tm 5.383333 0 Td 44.135802 Tz (described ) Tj 2.6 0 Td 48.888889 Tz (above ) Tj 1.533333 0 Td 11.111111 Tz (. ) Tj 0.333333 0 Td 41.666667 Tz (In ) Tj 0.716667 0 Td 42.283951 Tz (preferred ) Tj 2.516667 0 Td 50.757576 Tz (embodiments ) Tj 3.316667 0 Td 25 Tz (, ) Tj 0.416667 0 Td 41.666667 Tz (a ) Tj 0.466667 0 Td 42.460317 Tz (nucleic ) Tj 2.033333 0 Td 43.055556 Tz (acid ) Tj 1.433333 0 Td 34.722222 Tz (65 ) Tj 0.85 0 Td 42.361111 Tz (material ) Tj 2.333333 0 Td 44.444444 Tz (derived ) Tj 2.15 0 Td 49.305556 Tz (from ) Tj 1.483333 0 Td 41.666667 Tz (a ) Tj 0.566667 0 Td 43.981481 Tz (source ) Tj 1.883333 0 Td 42.222222 Tz (other ) Tj 1.533333 0 Td 45.138889 Tz (than ) Tj 1.35 0 Td 41.666667 Tz (the ) Tj 1.033333 0 Td 44.166667 Tz (referenced ) Tj 55.714286 0 0 55.714286 0 212.135772 Tm 5.797436 0 Td 45.204179 Tz (construct ) Tj 2.638462 0 Td 50.854701 Tz (of ) Tj 0.717949 0 Td 44.871795 Tz (the ) Tj 1.005128 0 Td 46.866097 Tz (invention ) Tj 2.728205 0 Td 32.905983 Tz (is ) Tj 0.592308 0 Td 50.854701 Tz (recombinant ) Tj 3.553846 0 Td 52.849003 Tz (and ) Tj 1.041026 0 Td 20.940171 Tz (/ ) Tj 0.125641 0 Td 44.871795 Tz (or ) Tj 0.735897 0 Td 41.880342 Tz (isolated ) Tj 2.064103 0 Td 20.940171 Tz (. ) Tj 0.358974 0 Td 46.367521 Tz (In ) Tj 1.938462 0 Td 44.444444 Tz (species ) Tj 1.938462 0 Td 14.957265 Tz (, ) Tj 0.341026 0 Td 53.846154 Tz (and ) Tj 1.166667 0 Td 34.401709 Tz (is ) Tj 0.646154 0 Td 46.068376 Tz (contrasted ) Tj 2.94359 0 Td 50.106838 Tz (with ) Tj 1.453846 0 Td 35.897436 Tz ( ) Tj 0.233333 0 Td 56.837607 Tz (homologous ) Tj 3.374359 0 Td 35.897436 Tz (, ) Tj 0.14359 0 Td 35.897436 Tz (" ) Tj 0.484615 0 Td 54.444444 Tz (which ) Tj 1.830769 0 Td 41.880342 Tz (refers ) Tj 55.18797 0 0 55.18797 0 171.326296 Tm 5.870845 0 Td 57.379655 Tz (some ) Tj 1.68515 0 Td 54.634217 Tz (embodiments ) Tj 3.913896 0 Td 51.339691 Tz (of ) Tj 0.815395 0 Td 45.299728 Tz (the ) Tj 1.105313 0 Td 47.313049 Tz (invention ) Tj 2.808583 0 Td 45.299728 Tz (the ) Tj 1.087193 0 Td 46.162579 Tz (nucleic ) Tj 2.246866 0 Td 46.054723 Tz (acid ) Tj 1.467711 0 Td 46.809718 Tz (con- ) Tj 2.482425 0 Td 40.769755 Tz (to ) Tj 0.761035 0 Td 45.299728 Tz (genetic ) Tj 2.138147 0 Td 46.054723 Tz (material ) Tj 2.464305 0 Td 47.888283 Tz (derived ) Tj 2.246866 0 Td 46.054723 Tz (from ) Tj 1.250272 0 Td 27.179837 Tz (, ) Tj 0.416757 0 Td 44.62862 Tz (naturally ) Tj 2.645504 0 Td 46.205722 Tz (associated ) Tj 2.971662 0 Td 47.564714 Tz (with ) Tj 1.232153 0 Td 27.179837 Tz (, ) Tj 32.857143 0 0 32.857143 0 1507 Tm 37.8 0 Td 71.014493 Tz (35 ) Tj ET Q endstream endobj 187 0 obj << /Length 1 >> stream q endstream endobj 188 0 obj << /Length 54588 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 60.952381 0 0 60.952381 0 3027.187879 Tm 17.521875 0 Td 84.765625 Tz (US ) Tj 1.44375 0 Td 59.0625 Tz (11,072,799 ) Tj 3.904687 0 Td 71.09375 Tz (B2 ) Tj 52.857143 0 0 52.857143 0 2971 Tm 14.17027 0 Td 69.369369 Tz (19 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 33.463889 0 Td 74.537037 Tz (20 ) Tj 60.119048 0 0 60.119048 0 2913.415446 Tm 5.372673 0 Td 42.970297 Tz (or ) Tj 0.798416 0 Td 42.046205 Tz (native ) Tj 1.813069 0 Td 38.811881 Tz (to ) Tj 0.515644 0 Td 13.861386 Tz (, ) Tj 0.432475 0 Td 41.584158 Tz (the ) Tj 1.081188 0 Td 41.584158 Tz (species ) Tj 2.079208 0 Td 47.128713 Tz (of ) Tj 0.798416 0 Td 41.584158 Tz (the ) Tj 1.047921 0 Td 42.970297 Tz (host ) Tj 1.347327 0 Td 41.029703 Tz (plant ) Tj 1.563564 0 Td 30.49505 Tz (\( ) Tj 0.249505 0 Td 44.009901 Tz (although ) Tj 2.395248 0 Td 44.356436 Tz (not ) Tj 2.079208 0 Td 47.128713 Tz (of ) Tj 0.698614 0 Td 51.980198 Tz (Fhb1 ) Tj 1.230891 0 Td 24.950495 Tz (, ) Tj 0.382574 0 Td 40.660066 Tz (for ) Tj 0.914851 0 Td 49.554455 Tz (improved ) Tj 2.578218 0 Td 41.237624 Tz (function ) Tj 2.045941 0 Td 19.405941 Tz (. ) Tj 0.349307 0 Td 52.673267 Tz (The ) Tj 1.164356 0 Td 38.465347 Tz (specific ) Tj 2.062574 0 Td 44.972497 Tz (mutations ) Tj 2.644752 0 Td 47.128713 Tz (can ) Tj 61.428571 0 0 61.428571 0 2872.231452 Tm 5.24186 0 Td 40.944327 Tz (necessarily ) Tj 2.930233 0 Td 37.984496 Tz (to ) Tj 0.716279 0 Td 40.697674 Tz (the ) Tj 0.976744 0 Td 42.054264 Tz (host ) Tj 1.237209 0 Td 40.155039 Tz (plant ) Tj 1.465116 0 Td 33.914729 Tz (itself ) Tj 1.286047 0 Td 27.131783 Tz (\) ) Tj 0.113953 0 Td 27.131783 Tz (. ) Tj 0.406977 0 Td 46.124031 Tz (For ) Tj 1.074419 0 Td 48.837209 Tz (example ) Tj 2.018605 0 Td 27.131783 Tz (, ) Tj 0.423256 0 Td 39.341085 Tz (in ) Tj 0.716279 0 Td 52.228682 Tz (some ) Tj 2.490698 0 Td 47.48062 Tz (be ) Tj 0.732558 0 Td 46.124031 Tz (based ) Tj 1.562791 0 Td 48.837209 Tz (on ) Tj 0.765116 0 Td 43.410853 Tz (information ) Tj 3.027907 0 Td 44.96124 Tz (gleaned ) Tj 2.051163 0 Td 48.837209 Tz (from ) Tj 1.334884 0 Td 48.449612 Tz (methods ) Tj 2.213953 0 Td 45.106589 Tz (provided ) Tj 2.327907 0 Td 48.837209 Tz (by ) Tj 59.785714 0 0 59.785714 0 2830.098976 Tm 5.402628 0 Td 50.432642 Tz (embodiments ) Tj 3.696535 0 Td 47.391477 Tz (of ) Tj 0.819594 0 Td 41.81601 Tz (the ) Tj 1.103943 0 Td 42.435506 Tz (invention ) Tj 2.32497 0 Td 25.089606 Tz (, ) Tj 0.501792 0 Td 41.81601 Tz (the ) Tj 1.087216 0 Td 42.373556 Tz (transgenic ) Tj 2.893668 0 Td 40.886765 Tz (plants ) Tj 1.839904 0 Td 40.886765 Tz (are ) Tj 2.007168 0 Td 36.240542 Tz (this ) Tj 1.25448 0 Td 43.055002 Tz (invention ) Tj 2.32497 0 Td 25.089606 Tz (, ) Tj 0.535245 0 Td 46.694544 Tz (such ) Tj 1.455197 0 Td 40.422143 Tz (as ) Tj 0.83632 0 Td 41.81601 Tz (the ) Tj 1.087216 0 Td 45.532988 Tz (use ) Tj 1.170848 0 Td 47.391477 Tz (of ) Tj 0.83632 0 Td 56.869773 Tz (known ) Tj 2.023895 0 Td 44.32497 Tz (techniques ) Tj 3.010753 0 Td 37.634409 Tz (to ) Tj 60 0 0 60 0 2790.97057 Tm 5.366667 0 Td 42.857143 Tz (created ) Tj 2.033333 0 Td 50 Tz (by ) Tj 0.833333 0 Td 43.434343 Tz (introducing ) Tj 3.1 0 Td 42.063492 Tz (genetic ) Tj 2 0 Td 41.666667 Tz (material ) Tj 2.266667 0 Td 47.222222 Tz (encoding ) Tj 2.5 0 Td 38.888889 Tz (a ) Tj 0.466667 0 Td 42.063492 Tz (protein ) Tj 3.05 0 Td 39.930556 Tz (identify ) Tj 2.116667 0 Td 40.555556 Tz (variations ) Tj 2.666667 0 Td 38.888889 Tz (in ) Tj 0.65 0 Td 42.592593 Tz (the ) Tj 0.983333 0 Td 47.916667 Tz (gene ) Tj 1.35 0 Td 38.888889 Tz (that ) Tj 1.133333 0 Td 40.123457 Tz (correlate ) Tj 2.366667 0 Td 46.527778 Tz (with ) Tj 1.316667 0 Td 49.305556 Tz (improved ) Tj 58.571429 0 0 58.571429 0 2748.996778 Tm 5.514634 0 Td 43.821138 Tz (conferring ) Tj 2.85122 0 Td 43.495935 Tz (disease ) Tj 2.014634 0 Td 41.829268 Tz (resistance ) Tj 2.560976 0 Td 14.227642 Tz (, ) Tj 0.32439 0 Td 36.280488 Tz (e.g. ) Tj 0.956098 0 Td 14.227642 Tz (, ) Tj 0.32439 0 Td 61.178862 Tz (FHB1 ) Tj 1.587805 0 Td 14.227642 Tz (, ) Tj 0.32439 0 Td 51.219512 Tz (from ) Tj 1.434146 0 Td 49.322493 Tz (one ) Tj 1.126829 0 Td 42.682927 Tz (species ) Tj 2.339024 0 Td 31.300813 Tz (5 ) Tj 0.785366 0 Td 44.105691 Tz (function ) Tj 2.134146 0 Td 19.918699 Tz (. ) Tj 58.136646 0 0 58.136646 0 2705.432328 Tm 5.555876 0 Td 40.135328 Tz (into ) Tj 1.152457 0 Td 43.002137 Tz (a ) Tj 0.39562 0 Td 44.435541 Tz (host ) Tj 1.221261 0 Td 43.002137 Tz (plant ) Tj 1.444872 0 Td 48.735755 Tz (of ) Tj 0.688034 0 Td 43.002137 Tz (a ) Tj 0.430021 0 Td 39.816793 Tz (different ) Tj 2.322115 0 Td 43.002137 Tz (species ) Tj 1.857692 0 Td 14.334046 Tz (, ) Tj 0.275214 0 Td 49.554843 Tz (wherein ) Tj 2.21891 0 Td 43.002137 Tz (the ) Tj 0.928846 0 Td 44.435541 Tz (host ) Tj 1.20406 0 Td 43.002137 Tz (plant ) Tj 3.250962 0 Td 44.435541 Tz (In ) Tj 0.739637 0 Td 55.186075 Tz (some ) Tj 1.530876 0 Td 51.863183 Tz (embodiments ) Tj 3.663782 0 Td 47.30235 Tz (of ) Tj 0.705235 0 Td 43.002137 Tz (the ) Tj 0.980449 0 Td 44.276274 Tz (invention ) Tj 2.390919 0 Td 25.801282 Tz (, ) Tj 0.378419 0 Td 43.002137 Tz (the ) Tj 0.980449 0 Td 43.821225 Tz (disease ) Tj 2.098504 0 Td 45.295584 Tz (resis ) Tj 64.081633 0 0 64.081633 0 2665.344805 Tm 5.024841 0 Td 40.746638 Tz (expresses ) Tj 2.48121 0 Td 36.41189 Tz (that ) Tj 1.139172 0 Td 41.396851 Tz (heterologous ) Tj 3.27707 0 Td 44.86465 Tz (gene ) Tj 1.342038 0 Td 43.471338 Tz (product ) Tj 1.794586 0 Td 26.008493 Tz (. ) Tj 0.405732 0 Td 50.716561 Tz (Thus ) Tj 1.154777 0 Td 23.407643 Tz (, ) Tj 0.436943 0 Td 38.492569 Tz (since ) Tj 1.435669 0 Td 44.214437 Tz (an ) Tj 1.732166 0 Td 40.573248 Tz (tance ) Tj 1.451274 0 Td 44.214437 Tz (of ) Tj 0.686624 0 Td 39.012739 Tz (a ) Tj 0.452548 0 Td 39.012739 Tz (plant ) Tj 1.388854 0 Td 28.609342 Tz (is ) Tj 0.592994 0 Td 45.839968 Tz (enhanced ) Tj 2.403185 0 Td 46.815287 Tz (by ) Tj 0.79586 0 Td 39.532909 Tz (increasing ) Tj 2.606051 0 Td 41.353503 Tz (expression ) Tj 2.699682 0 Td 44.214437 Tz (of ) Tj 0.702229 0 Td 39.012739 Tz (a ) Tj 62.352941 0 0 62.352941 0 2619.591231 Tm 5.180189 0 Td 46.925227 Tz (exogenous ) Tj 2.886792 0 Td 42.003594 Tz (nucleic ) Tj 2.19717 0 Td 40.762579 Tz (acid ) Tj 1.299057 0 Td 47.444969 Tz (molecule ) Tj 2.678302 0 Td 29.402516 Tz (is ) Tj 0.769811 0 Td 42.767296 Tz (heterologous ) Tj 3.496226 0 Td 44.772013 Tz (with ) Tj 2.293396 0 Td 40.47619 Tz (disease ) Tj 1.876415 0 Td 39.292453 Tz (resistance ) Tj 2.55 0 Td 45.440252 Tz (encoding ) Tj 2.357547 0 Td 40.47619 Tz (nucleic ) Tj 1.908491 0 Td 41.430818 Tz (acid ) Tj 1.186792 0 Td 44.772013 Tz (such ) Tj 1.250943 0 Td 38.757862 Tz (as ) Tj 0.673585 0 Td 50.117925 Tz (Fhb1 ) Tj 1.250943 0 Td 18.710692 Tz (. ) Tj 0.288679 0 Td 42.767296 Tz (This ) Tj 61.623377 0 0 61.623377 0 2583.160407 Tm 5.209062 0 Td 40.955392 Tz (respect ) Tj 1.979768 0 Td 36.512118 Tz (to ) Tj 0.730242 0 Td 40.56902 Tz (the ) Tj 0.989884 0 Td 41.921321 Tz (host ) Tj 1.281981 0 Td 41.650861 Tz (plant ) Tj 1.200843 0 Td 27.046013 Tz (, ) Tj 0.421918 0 Td 40.56902 Tz (the ) Tj 0.989884 0 Td 44.502986 Tz (transformed ) Tj 3.196839 0 Td 40.0281 Tz (plant ) Tj 1.49294 0 Td 35.700738 Tz (cells ) Tj 1.346891 0 Td 38.540569 Tz (will ) Tj 2.190727 0 Td 46.879756 Tz (can ) Tj 0.973656 0 Td 45.978223 Tz (be ) Tj 0.68156 0 Td 45.076689 Tz (accomplished ) Tj 3.310432 0 Td 27.046013 Tz (, ) Tj 0.324552 0 Td 39.667486 Tz (for ) Tj 0.81138 0 Td 47.523709 Tz (example ) Tj 2.060906 0 Td 27.046013 Tz (, ) Tj 0.275869 0 Td 48.682824 Tz (by ) Tj 0.74647 0 Td 42.29013 Tz (introducing ) Tj 2.920969 0 Td 45.978223 Tz (an ) Tj 0.74647 0 Td 47.78129 Tz (expres ) Tj 58.571429 0 0 58.571429 0 2537.617231 Tm 5.514634 0 Td 44.715447 Tz (contain ) Tj 2.04878 0 Td 39.837398 Tz (transcripts ) Tj 2.85122 0 Td 48.373984 Tz (of ) Tj 0.7 0 Td 42.682927 Tz (the ) Tj 0.956098 0 Td 43.089431 Tz (nucleic ) Tj 2.031707 0 Td 44.105691 Tz (acid ) Tj 1.229268 0 Td 47.425474 Tz (molecules ) Tj 2.782927 0 Td 45.528455 Tz (introduced ) Tj 3.158537 0 Td 35.569106 Tz (10 ) Tj 0.887805 0 Td 43.394309 Tz (sion ) Tj 1.246341 0 Td 40.904472 Tz (cassette ) Tj 2.202439 0 Td 46.95122 Tz (of ) Tj 0.717073 0 Td 42.682927 Tz (the ) Tj 1.007317 0 Td 44.263776 Tz (invention ) Tj 2.595122 0 Td 47.662602 Tz (with ) Tj 1.365854 0 Td 42.682927 Tz (a ) Tj 0.460976 0 Td 49.085366 Tz (promoter ) Tj 2.578049 0 Td 51.219512 Tz (and ) Tj 1.007317 0 Td 19.918699 Tz (/ ) Tj 0.153659 0 Td 38.414634 Tz (or ) Tj 0.665854 0 Td 43.821138 Tz (other ) Tj 58.655462 0 0 58.655462 0 2500.549464 Tm 5.489685 0 Td 39.780325 Tz (that ) Tj 1.125215 0 Td 53.419293 Tz (would ) Tj 1.756017 0 Td 44.516078 Tz (not ) Tj 0.971777 0 Td 49.725406 Tz (be ) Tj 0.784241 0 Td 44.042502 Tz (detected ) Tj 2.301576 0 Td 39.780325 Tz (in ) Tj 0.647851 0 Td 42.621777 Tz (a ) Tj 0.443266 0 Td 42.215855 Tz (control ) Tj 1.960602 0 Td 42.053486 Tz (plant ) Tj 1.44914 0 Td 40.654618 Tz (qualitatively ) Tj 3.358596 0 Td 44.042502 Tz (or ) Tj 1.807163 0 Td 41.310337 Tz (transcription ) Tj 3.563181 0 Td 43.474212 Tz (regulatory ) Tj 2.983524 0 Td 46.173591 Tz (elements ) Tj 2.591404 0 Td 39.780325 Tz (that ) Tj 1.295702 0 Td 50.334288 Tz (promote ) Tj 2.472063 0 Td 40.06447 Tz (relatively ) Tj 60.204082 0 0 60.204082 0 2457.637042 Tm 5.365085 0 Td 40.338983 Tz (quantitatively ) Tj 3.753898 0 Td 27.683616 Tz (\( ) Tj 0.199322 0 Td 34.60452 Tz (e.g. ) Tj 0.913559 0 Td 13.841808 Tz (, ) Tj 0.448475 0 Td 49.830508 Tz (by ) Tj 0.94678 0 Td 64.595104 Tz (PCR ) Tj 1.179322 0 Td 27.683616 Tz (\) ) Tj 0.249153 0 Td 11.073446 Tz (. ) Tj 0.431864 0 Td 38.757062 Tz (If ) Tj 0.365424 0 Td 24.915254 Tz (, ) Tj 0.531525 0 Td 51.214689 Tz (on ) Tj 0.930169 0 Td 41.525424 Tz (the ) Tj 1.096271 0 Td 42.632768 Tz (other ) Tj 1.577966 0 Td 51.214689 Tz (hand ) Tj 1.212542 0 Td 24.915254 Tz (, ) Tj 0.498305 0 Td 48.446328 Tz (an ) Tj 1.827119 0 Td 46.370056 Tz (high ) Tj 1.328814 0 Td 39.218456 Tz (levels ) Tj 1.677627 0 Td 45.677966 Tz (of ) Tj 0.730847 0 Td 42.355932 Tz (expression ) Tj 2.624407 0 Td 27.683616 Tz (. ) Tj 0.398644 0 Td 42.909605 Tz (In ) Tj 0.730847 0 Td 42.632768 Tz (other ) Tj 1.494915 0 Td 50.333847 Tz (embodiments ) Tj 3.305424 0 Td 24.915254 Tz (, ) Tj 0.415254 0 Td 27.683616 Tz (it ) Tj 0.564746 0 Td 47.062147 Tz (can ) Tj 1.063051 0 Td 48.446328 Tz (be ) Tj 64.107143 0 0 64.107143 0 2416.248544 Tm 5.03844 0 Td 45.641184 Tz (exogenous ) Tj 2.885794 0 Td 39.368617 Tz (nucleic ) Tj 2.10585 0 Td 39.647168 Tz (acid ) Tj 1.357103 0 Td 44.196843 Tz (molecule ) Tj 2.542618 0 Td 29.897864 Tz (is ) Tj 0.779944 0 Td 47.836583 Tz (homologous ) Tj 3.291365 0 Td 43.54689 Tz (with ) Tj 2.215042 0 Td 44.630145 Tz (accomplished ) Tj 3.431755 0 Td 44.196843 Tz (by ) Tj 0.779944 0 Td 44.485711 Tz (modifying ) Tj 2.620613 0 Td 39.863819 Tz (the ) Tj 0.904735 0 Td 44.846797 Tz (promoter ) Tj 2.339833 0 Td 45.063448 Tz (and ) Tj 0.935933 0 Td 20.798514 Tz (/ ) Tj 0.124791 0 Td 36.3974 Tz (or ) Tj 0.655153 0 Td 41.597029 Tz (transcrip ) Tj 60.974026 0 0 60.974026 0 2374.519737 Tm 5.264537 0 Td 41.391551 Tz (respect ) Tj 2.050053 0 Td 36.900958 Tz (to ) Tj 0.77082 0 Td 41.9122 Tz (the ) Tj 1.066028 0 Td 42.367767 Tz (host ) Tj 1.328435 0 Td 44.28115 Tz (plant ) Tj 1.180831 0 Td 27.334043 Tz (, ) Tj 0.508413 0 Td 41.001065 Tz (the ) Tj 1.049627 0 Td 44.976926 Tz (transformed ) Tj 3.263685 0 Td 40.08993 Tz (plants ) Tj 1.787646 0 Td 47.379008 Tz (can ) Tj 1.14803 0 Td 47.834576 Tz (be ) Tj 1.836848 0 Td 39.634363 Tz (tion ) Tj 1.14803 0 Td 41.821086 Tz (regulatory ) Tj 2.738871 0 Td 44.41782 Tz (elements ) Tj 2.378062 0 Td 42.172524 Tz (already ) Tj 1.984452 0 Td 41.782038 Tz (present ) Tj 1.984452 0 Td 38.267661 Tz (in ) Tj 0.656017 0 Td 41.001065 Tz (the ) Tj 0.934824 0 Td 44.827831 Tz (plant ) Tj 1.197231 0 Td 27.334043 Tz (, ) Tj 0.410011 0 Td 41.001065 Tz (or ) Tj 0.688818 0 Td 49.201278 Tz (by ) Tj 65.714286 0 0 65.714286 0 2332.364209 Tm 4.9 0 Td 38.628763 Tz (distinguished ) Tj 3.378261 0 Td 44.384058 Tz (from ) Tj 1.4 0 Td 36.956522 Tz (control ) Tj 1.917391 0 Td 37.198068 Tz (plants ) Tj 1.643478 0 Td 42.608696 Tz (based ) Tj 1.613043 0 Td 46.92029 Tz (upon ) Tj 1.46087 0 Td 37.282609 Tz (additional ) Tj 2.647826 0 Td 30.434783 Tz (15 ) Tj 0.791304 0 Td 39.196311 Tz (introducing ) Tj 2.86087 0 Td 50.724638 Tz (new ) Tj 1.217391 0 Td 43.75 Tz (promoter ) Tj 2.373913 0 Td 44.806763 Tz (and ) Tj 0.852174 0 Td 17.753623 Tz (/ ) Tj 0.152174 0 Td 38.043478 Tz (or ) Tj 0.7 0 Td 36.677815 Tz (transcription ) Tj 3.134783 0 Td 39.057971 Tz (regulatory ) Tj 63.533835 0 0 63.533835 0 2289.754491 Tm 5.083905 0 Td 41.710059 Tz (expression ) Tj 2.880355 0 Td 43.284024 Tz (of ) Tj 0.818462 0 Td 37.679756 Tz (transcripts ) Tj 2.455385 0 Td 26.232742 Tz (, ) Tj 0.503669 0 Td 48.268245 Tz (which ) Tj 1.810059 0 Td 44.595661 Tz (can ) Tj 1.148994 0 Td 45.907298 Tz (be ) Tj 0.928639 0 Td 40.66075 Tz (detected ) Tj 2.297988 0 Td 42.497041 Tz (using ) Tj 2.486864 0 Td 42.628205 Tz (elements ) Tj 2.329467 0 Td 36.725838 Tz (into ) Tj 1.148994 0 Td 39.349112 Tz (the ) Tj 0.960118 0 Td 39.349112 Tz (plant ) Tj 1.448047 0 Td 37.600263 Tz (for ) Tj 0.928639 0 Td 40.806487 Tz (increased ) Tj 2.471124 0 Td 40.398422 Tz (expression ) Tj 2.502604 0 Td 26.232742 Tz (. ) Tj 0.409231 0 Td 39.349112 Tz (In ) Tj 0.724024 0 Td 40.398422 Tz (other ) Tj 61.428571 0 0 61.428571 0 2251.897196 Tm 5.25814 0 Td 27.131783 Tz (" ) Tj 0.406977 0 Td 37.758398 Tz (quantitative ) Tj 2.816279 0 Td 27.131783 Tz ( ) Tj 0.390698 0 Td 63.307494 Tz (PCR ) Tj 1.351163 0 Td 43.682171 Tz (techniques ) Tj 2.572093 0 Td 27.131783 Tz (. ) Tj 62.857143 0 0 62.857143 0 2247.291123 Tm 20.634091 0 Td 48.69146 Tz (embodiments ) Tj 3.197727 0 Td 23.863636 Tz (, ) Tj 0.493182 0 Td 41.540404 Tz (increased ) Tj 2.593182 0 Td 42.159091 Tz (expression ) Tj 2.879545 0 Td 45.959596 Tz (can ) Tj 1.161364 0 Td 45.075758 Tz (be ) Tj 0.906818 0 Td 44.081439 Tz (achieved ) Tj 2.45 0 Td 47.727273 Tz (by ) Tj 60.324675 0 0 60.324675 0 2207.244695 Tm 5.984284 0 Td 41.442411 Tz (In ) Tj 0.663079 0 Td 41.442411 Tz (the ) Tj 0.911733 0 Td 42.62648 Tz (present ) Tj 1.972659 0 Td 42.977315 Tz (invention ) Tj 2.304198 0 Td 24.865447 Tz (, ) Tj 0.364693 0 Td 26.24686 Tz (it ) Tj 0.497309 0 Td 31.772515 Tz (is ) Tj 0.580194 0 Td 38.679584 Tz (in ) Tj 0.663079 0 Td 52.493721 Tz (some ) Tj 1.458773 0 Td 41.994977 Tz (cases ) Tj 1.47535 0 Td 46.277359 Tz (advantageous ) Tj 4.608396 0 Td 42.949408 Tz (introducing ) Tj 3.066738 0 Td 52.493721 Tz (more ) Tj 1.491927 0 Td 44.895945 Tz (than ) Tj 1.30958 0 Td 48.809951 Tz (one ) Tj 1.127234 0 Td 49.040187 Tz (copy ) Tj 1.425619 0 Td 46.968066 Tz (of ) Tj 0.729386 0 Td 41.442411 Tz (the ) Tj 0.978041 0 Td 42.23179 Tz (nucleic ) Tj 2.038967 0 Td 42.823825 Tz (acid ) Tj 1.259849 0 Td 37.988877 Tz (into ) Tj 1.193541 0 Td 38.679584 Tz (a ) Tj 60.451128 0 0 60.451128 0 2168.336375 Tm 5.326617 0 Td 37.220149 Tz (to ) Tj 0.628607 0 Td 42.887415 Tz (introduce ) Tj 2.464801 0 Td 48.248342 Tz (an ) Tj 0.711318 0 Td 48.524046 Tz (endogenous ) Tj 3.093408 0 Td 46.869818 Tz (and ) Tj 0.94291 0 Td 19.299337 Tz (/ ) Tj 0.148881 0 Td 39.977197 Tz (or ) Tj 0.595522 0 Td 44.112769 Tz (heterologous ) Tj 3.325 0 Td 42.143449 Tz (nucleic ) Tj 1.935448 0 Td 42.734245 Tz (acid ) Tj 2.266294 0 Td 43.56136 Tz (plant ) Tj 1.191045 0 Td 27.570481 Tz (. ) Tj 0.380473 0 Td 48.524046 Tz (These ) Tj 1.670771 0 Td 48.70785 Tz (and ) Tj 1.075249 0 Td 41.907131 Tz (other ) Tj 1.439179 0 Td 43.56136 Tz (techniques ) Tj 2.845274 0 Td 39.517689 Tz (for ) Tj 0.893284 0 Td 41.907131 Tz (increasing ) Tj 2.729478 0 Td 43.837065 Tz (expression ) Tj 68.571429 0 0 68.571429 0 2120.383728 Tm 4.710417 0 Td 41.319444 Tz (encoding ) Tj 2.129167 0 Td 36.458333 Tz (a ) Tj 0.364583 0 Td 36.805556 Tz (protein ) Tj 1.691667 0 Td 37.430556 Tz (conferring ) Tj 2.40625 0 Td 37.152778 Tz (disease ) Tj 1.691667 0 Td 35 Tz (resistance ) Tj 2.070833 0 Td 29.166667 Tz (, ) Tj 0.35 0 Td 30.989583 Tz (e.g. ) Tj 0.802083 0 Td 12.152778 Tz (, ) Tj 0.2625 0 Td 52.256944 Tz (FHB1 ) Tj 1.6625 0 Td 32.8125 Tz (20 ) Tj 0.772917 0 Td 41.319444 Tz (can ) Tj 0.860417 0 Td 42.534722 Tz (be ) Tj 0.641667 0 Td 41.927083 Tz (used ) Tj 1.1375 0 Td 36.255787 Tz (individually ) Tj 2.75625 0 Td 37.673611 Tz (or ) Tj 0.670833 0 Td 21.875 Tz (in ) Tj 0.525 0 Td 40.214646 Tz (combination ) Tj 2.8 0 Td 31.597222 Tz (to ) Tj 0.525 0 Td 40.625 Tz (achieve ) Tj 1.779167 0 Td 38.888889 Tz (higher ) Tj 62.922078 0 0 62.922078 0 2082.110749 Tm 5.117441 0 Td 37.839697 Tz (protein ) Tj 1.652838 0 Td 26.487788 Tz (, ) Tj 0.47678 0 Td 42.002064 Tz (derived ) Tj 2.050155 0 Td 47.678019 Tz (from ) Tj 1.430341 0 Td 39.731682 Tz (a ) Tj 0.540351 0 Td 30.196078 Tz (first ) Tj 1.19195 0 Td 39.201926 Tz (plant ) Tj 1.462126 0 Td 44.587777 Tz (having ) Tj 1.891228 0 Td 37.347781 Tz (relatively ) Tj 2.526935 0 Td 44.367045 Tz (high ) Tj 2.272652 0 Td 37.524366 Tz (levels ) Tj 1.557482 0 Td 45.02924 Tz (of ) Tj 0.667492 0 Td 56.948744 Tz (FHB1 ) Tj 1.636945 0 Td 34.434125 Tz (activity ) Tj 1.700516 0 Td 26.487788 Tz (, ) Tj 0.349639 0 Td 47.678019 Tz (by ) Tj 0.778741 0 Td 41.056072 Tz (elevated ) Tj 2.161404 0 Td 42.115583 Tz (expression ) Tj 2.717647 0 Td 43.70485 Tz (of ) Tj 0.667492 0 Td 50.326797 Tz (Fhb1 ) Tj 1.176058 0 Td 23.839009 Tz (, ) Tj 0.365531 0 Td 41.056072 Tz (or ) Tj 58.071429 0 0 58.071429 0 2041.008866 Tm 5.562116 0 Td 43.870439 Tz (disease ) Tj 2.066421 0 Td 41.615416 Tz (resistance ) Tj 2.703567 0 Td 40.180402 Tz (into ) Tj 1.188192 0 Td 43.050431 Tz (a ) Tj 0.482165 0 Td 48.790488 Tz (second ) Tj 1.945879 0 Td 42.476425 Tz (plant ) Tj 1.463715 0 Td 47.355474 Tz (with ) Tj 1.343173 0 Td 43.050431 Tz (respect ) Tj 1.99754 0 Td 38.745387 Tz (to ) Tj 0.688807 0 Td 52.234522 Tz (which ) Tj 2.910209 0 Td 54.530545 Tz (some ) Tj 1.549815 0 Td 43.624436 Tz (other ) Tj 1.515375 0 Td 43.870439 Tz (disease ) Tj 2.0492 0 Td 42.189422 Tz (resistance ) Tj 2.755228 0 Td 44.198442 Tz (conferring ) Tj 2.875769 0 Td 50.225502 Tz (gene ) Tj 1.239852 0 Td 20.090201 Tz (, ) Tj 0.327183 0 Td 40.180402 Tz (relative ) Tj 2.135301 0 Td 38.745387 Tz (to ) Tj 0.723247 0 Td 43.050431 Tz (a ) Tj 54.285714 0 0 54.285714 0 2000.270811 Tm 5.95 0 Td 54.111842 Tz (enhanced ) Tj 2.928947 0 Td 46.929825 Tz (disease ) Tj 2.302632 0 Td 45.131579 Tz (resistance ) Tj 3.057895 0 Td 35.307018 Tz (is ) Tj 0.792105 0 Td 46.929825 Tz (desired ) Tj 2.026316 0 Td 12.280702 Tz (. ) Tj 0.460526 0 Td 46.052632 Tz (In ) Tj 0.921053 0 Td 58.333333 Tz (some ) Tj 1.805263 0 Td 52.192982 Tz (embodi- ) Tj 3.628947 0 Td 46.052632 Tz (control ) Tj 2.155263 0 Td 48.508772 Tz (plant ) Tj 1.363158 0 Td 33.77193 Tz (. ) Tj 59.931973 0 0 59.931973 0 1957.296845 Tm 5.372758 0 Td 48.944381 Tz (ments ) Tj 1.685244 0 Td 42.640938 Tz (the ) Tj 0.984449 0 Td 31.702611 Tz (first ) Tj 1.151305 0 Td 41.713961 Tz (plant ) Tj 1.468331 0 Td 49.129777 Tz (and ) Tj 1.117934 0 Td 47.275823 Tz (second ) Tj 1.902157 0 Td 41.157775 Tz (plant ) Tj 1.468331 0 Td 40.786984 Tz (are ) Tj 0.967764 0 Td 38.624038 Tz (different ) Tj 2.319296 0 Td 41.316686 Tz (species ) Tj 1.802043 0 Td 13.904654 Tz (, ) Tj 2.018956 0 Td 43.104427 Tz (In ) Tj 0.700795 0 Td 52.837684 Tz (some ) Tj 1.451646 0 Td 50.309566 Tz (embodiments ) Tj 3.303746 0 Td 25.028377 Tz (, ) Tj 0.350397 0 Td 41.713961 Tz (the ) Tj 0.917707 0 Td 43.567915 Tz (invention ) Tj 2.502838 0 Td 44.147276 Tz (provides ) Tj 2.302611 0 Td 41.713961 Tz (a ) Tj 0.41714 0 Td 40.91941 Tz (variety ) Tj 1.902157 0 Td 47.275823 Tz (of ) Tj 61.428571 0 0 61.428571 0 1914.33566 Tm 5.24186 0 Td 45.03876 Tz (while ) Tj 1.660465 0 Td 37.984496 Tz (in ) Tj 0.765116 0 Td 41.24031 Tz (other ) Tj 1.530233 0 Td 49.330514 Tz (embodiments ) Tj 3.565116 0 Td 43.410853 Tz (they ) Tj 1.351163 0 Td 39.793282 Tz (are ) Tj 1.04186 0 Td 37.683032 Tz (different ) Tj 2.360465 0 Td 36.434109 Tz (strains ) Tj 1.855814 0 Td 42.054264 Tz (or ) Tj 0.87907 0 Td 35.271318 Tz (25 ) Tj 0.846512 0 Td 48.449612 Tz (methods ) Tj 2.27907 0 Td 38.888889 Tz (for ) Tj 0.911628 0 Td 46.72696 Tz (improving ) Tj 2.751163 0 Td 41.085271 Tz (disease ) Tj 1.937209 0 Td 39.883721 Tz (resistance ) Tj 2.62093 0 Td 39.341085 Tz (in ) Tj 0.667442 0 Td 41.149871 Tz (plants ) Tj 1.432558 0 Td 27.131783 Tz (, ) Tj 0.423256 0 Td 44.767442 Tz (prefer ) Tj 59.404762 0 0 59.404762 0 1874.905422 Tm 5.437275 0 Td 39.278557 Tz (cultivars ) Tj 2.33988 0 Td 47.695391 Tz (of ) Tj 0.69018 0 Td 42.084168 Tz (the ) Tj 0.976353 0 Td 51.903808 Tz (same ) Tj 1.464529 0 Td 42.084168 Tz (species ) Tj 1.83487 0 Td 11.222445 Tz (. ) Tj 0.303006 0 Td 52.371409 Tz (The ) Tj 1.144689 0 Td 42.885772 Tz (disease ) Tj 1.986373 0 Td 40.961924 Tz (resistance ) Tj 2.777555 0 Td 45.357381 Tz (encod- ) Tj 2.878557 0 Td 40.681363 Tz (ably ) Tj 1.01002 0 Td 28.056112 Tz (, ) Tj 0.31984 0 Td 44.88978 Tz (but ) Tj 0.959519 0 Td 43.954576 Tz (not ) Tj 0.976353 0 Td 42.594279 Tz (exclusively ) Tj 2.760721 0 Td 28.056112 Tz (, ) Tj 0.370341 0 Td 41.616566 Tz (grains ) Tj 1.717034 0 Td 46.292585 Tz (such ) Tj 1.279359 0 Td 40.681363 Tz (as ) Tj 0.656513 0 Td 49.93988 Tz (wheat ) Tj 1.683367 0 Td 42.084168 Tz (or ) Tj 0.656513 0 Td 43.486974 Tz (barley ) Tj 1.582365 0 Td 11.222445 Tz (. ) Tj 0.269339 0 Td 48.630595 Tz (For ) Tj 59.571429 0 0 59.571429 0 1834.548201 Tm 5.405276 0 Td 42.899014 Tz (ing ) Tj 1.007194 0 Td 46.86251 Tz (sequence ) Tj 2.467626 0 Td 47.56195 Tz (can ) Tj 1.023981 0 Td 48.960831 Tz (be ) Tj 0.788969 0 Td 40.567546 Tz (isolated ) Tj 2.131894 0 Td 50.359712 Tz (from ) Tj 1.393285 0 Td 41.966427 Tz (the ) Tj 0.956835 0 Td 31.894484 Tz (first ) Tj 1.141487 0 Td 43.645084 Tz (plant ) Tj 1.242206 0 Td 27.977618 Tz (, ) Tj 0.369305 0 Td 43.365308 Tz (or ) Tj 0.755396 0 Td 42.765787 Tz (synthe- ) Tj 3.088729 0 Td 47.961631 Tz (example ) Tj 2.081535 0 Td 27.977618 Tz (, ) Tj 0.503597 0 Td 41.966427 Tz (the ) Tj 1.091127 0 Td 43.831601 Tz (invention ) Tj 2.669065 0 Td 44.414468 Tz (provides ) Tj 2.467626 0 Td 50.359712 Tz (methods ) Tj 2.467626 0 Td 40.101252 Tz (for ) Tj 1.040767 0 Td 41.203401 Tz (genetically ) Tj 60.840336 0 0 60.840336 0 1792.859615 Tm 5.325414 0 Td 41.09116 Tz (sized ) Tj 1.495718 0 Td 46.569982 Tz (based ) Tj 1.660083 0 Td 51.36395 Tz (upon ) Tj 1.512155 0 Td 40.482402 Tz (available ) Tj 2.46547 0 Td 41.482505 Tz (genetic ) Tj 2.038122 0 Td 42.585384 Tz (information ) Tj 2.925691 0 Td 19.175875 Tz (. ) Tj 0.460221 0 Td 45.885129 Tz (Advanta- ) Tj 3.418785 0 Td 47.483118 Tz (modifying ) Tj 2.794199 0 Td 43.830571 Tz (a ) Tj 0.525967 0 Td 40.543278 Tz (plant ) Tj 1.479282 0 Td 49.309392 Tz (by ) Tj 0.854696 0 Td 42.834422 Tz (introducing ) Tj 3.057182 0 Td 43.830571 Tz (a ) Tj 0.525967 0 Td 41.482505 Tz (nucleic ) Tj 2.005249 0 Td 42.460866 Tz (acid ) Tj 1.282044 0 Td 46.569982 Tz (encoding ) Tj 60.285714 0 0 60.285714 0 1751.204891 Tm 5.341232 0 Td 45.813586 Tz (geously ) Tj 1.874408 0 Td 27.64613 Tz (, ) Tj 0.514218 0 Td 44.233807 Tz (expression ) Tj 2.985782 0 Td 44.233807 Tz (or ) Tj 0.862559 0 Td 44.628752 Tz (overexpression ) Tj 4.080569 0 Td 46.99842 Tz (of ) Tj 0.829384 0 Td 42.390732 Tz (the ) Tj 1.094787 0 Td 49.148675 Tz (exogenous ) Tj 3.93128 0 Td 41.864139 Tz (disease ) Tj 2.040284 0 Td 40.63981 Tz (resistance ) Tj 2.488152 0 Td 13.823065 Tz (, ) Tj 0.398104 0 Td 35.248815 Tz (e.g. ) Tj 0.912322 0 Td 13.823065 Tz (, ) Tj 0.414692 0 Td 49.07188 Tz (Fhbl ) Tj 1.542654 0 Td 42.851501 Tz (or ) Tj 0.779621 0 Td 48.841496 Tz (one ) Tj 1.177725 0 Td 45.616114 Tz (of ) Tj 0.763033 0 Td 41.469194 Tz (the ) Tj 1.045024 0 Td 42.022117 Tz (other ) Tj 1.526066 0 Td 41.864139 Tz (nucleic ) Tj 60 0 0 60 0 1708.604089 Tm 5.383333 0 Td 44.444444 Tz (and ) Tj 1 0 Td 19.444444 Tz (/ ) Tj 0.166667 0 Td 34.722222 Tz (or ) Tj 0.566667 0 Td 44.444444 Tz (heterologous ) Tj 3.383333 0 Td 42.460317 Tz (nucleic ) Tj 1.983333 0 Td 42.361111 Tz (acid ) Tj 1.2 0 Td 41.358025 Tz (increases ) Tj 2.416667 0 Td 41.666667 Tz (the ) Tj 0.95 0 Td 42.063492 Tz (disease ) Tj 1.933333 0 Td 37.037037 Tz (resis- ) Tj 1.75 0 Td 37.5 Tz (30 ) Tj 0.883333 0 Td 41.111111 Tz (acids ) Tj 1.5 0 Td 46.180556 Tz (provided ) Tj 2.45 0 Td 51.388889 Tz (by ) Tj 0.866667 0 Td 41.666667 Tz (the ) Tj 1.016667 0 Td 41.666667 Tz (invention ) Tj 2.383333 0 Td 19.444444 Tz (. ) Tj 0.35 0 Td 52.777778 Tz (The ) Tj 1.216667 0 Td 41.666667 Tz (genetic ) Tj 2.016667 0 Td 43.75 Tz (modification ) Tj 58.571429 0 0 58.571429 0 1665.314991 Tm 5.497561 0 Td 44.390244 Tz (tance ) Tj 1.570732 0 Td 48.373984 Tz (of ) Tj 0.734146 0 Td 42.682927 Tz (the ) Tj 0.990244 0 Td 46.821877 Tz (transformed ) Tj 3.346341 0 Td 48.373984 Tz (second ) Tj 1.946341 0 Td 43.821138 Tz (plant ) Tj 1.246341 0 Td 28.455285 Tz (. ) Tj 61.428571 0 0 61.428571 0 1665.8 Tm 21.113953 0 Td 46.124031 Tz (can ) Tj 1.090698 0 Td 47.48062 Tz (be ) Tj 0.830233 0 Td 40.155039 Tz (transgenic ) Tj 2.474419 0 Td 27.131783 Tz (, ) Tj 0.455814 0 Td 29.166667 Tz (i.e. ) Tj 0.765116 0 Td 13.565891 Tz (, ) Tj 0.390698 0 Td 41.375969 Tz (introduction ) Tj 3.239535 0 Td 46.124031 Tz (of ) Tj 0.765116 0 Td 40.697674 Tz (a ) Tj 0.52093 0 Td 41.085271 Tz (nucleic ) Tj 2.034884 0 Td 42.054264 Tz (acid ) Tj 1.253488 0 Td 43.410853 Tz (not ) Tj 59.795918 0 0 59.795918 0 1624.41095 Tm 6.037201 0 Td 45.790671 Tz (Transformation ) Tj 4.080546 0 Td 44.03868 Tz (techniques ) Tj 2.909898 0 Td 39.950702 Tz (for ) Tj 0.936519 0 Td 40.879788 Tz (plants ) Tj 1.739249 0 Td 40.879788 Tz (are ) Tj 0.986689 0 Td 43.899317 Tz (well ) Tj 1.304437 0 Td 56.860068 Tz (known ) Tj 1.939932 0 Td 40.415245 Tz (in ) Tj 1.739249 0 Td 42.273417 Tz (native ) Tj 1.739249 0 Td 37.627986 Tz (to ) Tj 0.702389 0 Td 41.808874 Tz (the ) Tj 0.969966 0 Td 42.923777 Tz (plant ) Tj 1.237543 0 Td 27.872582 Tz (, ) Tj 0.384642 0 Td 35.537543 Tz (e.g. ) Tj 0.919795 0 Td 13.936291 Tz (, ) Tj 0.351195 0 Td 41.808874 Tz (a ) Tj 0.484983 0 Td 48.080205 Tz (gene ) Tj 1.404778 0 Td 44.197952 Tz (derived ) Tj 2.07372 0 Td 50.170648 Tz (from ) Tj 1.438225 0 Td 44.197952 Tz (another ) Tj 2.056997 0 Td 41.808874 Tz (plant ) Tj 59.480519 0 0 59.480519 0 1583.713178 Tm 5.413537 0 Td 42.030568 Tz (the ) Tj 1.025546 0 Td 35.492479 Tz (art ) Tj 0.90786 0 Td 49.502669 Tz (and ) Tj 1.143231 0 Td 43.631732 Tz (include ) Tj 2.101528 0 Td 48.568656 Tz (any ) Tj 1.126419 0 Td 45.143943 Tz (technique ) Tj 2.706769 0 Td 44.20993 Tz (involving ) Tj 2.63952 0 Td 42.030568 Tz (the ) Tj 1.008734 0 Td 46.233624 Tz (uptake ) Tj 1.933406 0 Td 47.634643 Tz (of ) Tj 1.782096 0 Td 39.22853 Tz (that ) Tj 1.126419 0 Td 46.233624 Tz (does ) Tj 1.294541 0 Td 44.832606 Tz (not ) Tj 0.991921 0 Td 42.310771 Tz (interbreed ) Tj 2.706769 0 Td 46.233624 Tz (with ) Tj 1.277729 0 Td 42.030568 Tz (the ) Tj 0.924672 0 Td 39.22853 Tz (target ) Tj 1.580349 0 Td 42.030568 Tz (plant ) Tj 1.294541 0 Td 14.010189 Tz (, ) Tj 0.30262 0 Td 40.162542 Tz (for ) Tj 0.90786 0 Td 42.030568 Tz (a ) Tj 0.45393 0 Td 41.096555 Tz (synthetic ) Tj 58.231293 0 0 58.231293 0 1542.017035 Tm 5.529673 0 Td 50.246625 Tz (exogenous ) Tj 3.02243 0 Td 43.341121 Tz (genetic ) Tj 2.112266 0 Td 43.290012 Tz (material ) Tj 2.387033 0 Td 52.949766 Tz (by ) Tj 0.910164 0 Td 42.932243 Tz (the ) Tj 1.06472 0 Td 46.366822 Tz (plant ) Tj 1.236449 0 Td 28.621495 Tz (, ) Tj 0.515187 0 Td 47.941005 Tz (such ) Tj 1.442523 0 Td 41.501168 Tz (as ) Tj 0.789953 0 Td 40.070093 Tz (particle ) Tj 3.245678 0 Td 50.087617 Tz (gene ) Tj 1.236449 0 Td 20.035047 Tz (. ) Tj 0.274766 0 Td 44.363318 Tz (In ) Tj 0.704089 0 Td 54.380841 Tz (some ) Tj 1.476869 0 Td 52.039082 Tz (embodiments ) Tj 3.417407 0 Td 25.759346 Tz (, ) Tj 0.326285 0 Td 43.886293 Tz (the ) Tj 0.961682 0 Td 42.932243 Tz (genetic ) Tj 1.974883 0 Td 45.078855 Tz (modification ) Tj 3.417407 0 Td 48.656542 Tz (can ) Tj 1.013201 0 Td 50.087617 Tz (be ) Tj 67.142857 0 0 67.142857 0 1494.810578 Tm 4.795745 0 Td 47.840103 Tz (bombardment ) Tj 3.217021 0 Td 17.375887 Tz (- ) Tj 0 0 Td 44.060284 Tz (mediated ) Tj 2.397872 0 Td 37.234043 Tz (delivery ) Tj 1.757447 0 Td 24.822695 Tz (, ) Tj 0.402128 0 Td 41.434806 Tz (Agrobacterium ) Tj 3.470213 0 Td 24.822695 Tz (- ) Tj 0.014894 0 Td 44.370567 Tz (mediated ) Tj 2.47234 0 Td 32.269504 Tz (35 ) Tj 0.789362 0 Td 37.234043 Tz (cisgenic ) Tj 1.846809 0 Td 12.411348 Tz (, ) Tj 0.32766 0 Td 34.751773 Tz (in ) Tj 0.625532 0 Td 45.177305 Tz (which ) Tj 1.578723 0 Td 39.095745 Tz (case ) Tj 1.146809 0 Td 37.234043 Tz (the ) Tj 0.893617 0 Td 37.588652 Tz (nucleic ) Tj 1.831915 0 Td 37.85461 Tz (acid ) Tj 1.131915 0 Td 27.304965 Tz (is ) Tj 0.580851 0 Td 39.361702 Tz (derived ) Tj 1.876596 0 Td 44.680851 Tz (from ) Tj 1.295745 0 Td 37.234043 Tz (a ) Tj 62.105263 0 0 62.105263 0 1458.367012 Tm 5.184746 0 Td 43.474576 Tz (techniques ) Tj 2.544068 0 Td 26.836158 Tz (, ) Tj 0.402542 0 Td 53.672316 Tz (PEG- ) Tj 1.529661 0 Td 41.596045 Tz (or ) Tj 0.692373 0 Td 40.254237 Tz (electroporation ) Tj 3.70339 0 Td 26.836158 Tz (- ) Tj 0.09661 0 Td 46.963277 Tz (mediated ) Tj 2.447458 0 Td 44.72693 Tz (uptake ) Tj 1.545763 0 Td 26.836158 Tz (, ) Tj 0.402542 0 Td 35.960452 Tz (viral ) Tj 2.334746 0 Td 39.870864 Tz (closely ) Tj 1.867797 0 Td 39.104116 Tz (related ) Tj 1.80339 0 Td 40.254237 Tz (plant ) Tj 1.384746 0 Td 36.899718 Tz (that ) Tj 1.078814 0 Td 44.548023 Tz (could ) Tj 1.497458 0 Td 46.963277 Tz (be ) Tj 0.75678 0 Td 42.362793 Tz (conventionally ) Tj 3.735593 0 Td 44.950565 Tz (bred ) Tj 1.255932 0 Td 44.279661 Tz (with ) Tj 55.102041 0 0 55.102041 0 1420.525114 Tm 5.88 0 Td 41.673525 Tz (infection ) Tj 2.377407 0 Td 24.197531 Tz (, ) Tj 0.417407 0 Td 48.395062 Tz (and ) Tj 1.052593 0 Td 24.197531 Tz (/ ) Tj 0.181481 0 Td 39.320988 Tz (or ) Tj 0.725926 0 Td 46.234568 Tz (microinjection ) Tj 3.938148 0 Td 30.246914 Tz (. ) Tj 60 0 0 60 0 1418.890244 Tm 21.6 0 Td 42.592593 Tz (the ) Tj 1.133333 0 Td 38.888889 Tz (target ) Tj 1.766667 0 Td 42.777778 Tz (plant ) Tj 1.216667 0 Td 27.777778 Tz (. ) Tj 0.583333 0 Td 38.888889 Tz (In ) Tj 0.866667 0 Td 41.358025 Tz (preferred ) Tj 2.633333 0 Td 50.505051 Tz (embodiments ) Tj 3.316667 0 Td 25 Tz (, ) Tj 0.583333 0 Td 40.740741 Tz (the ) Tj 1.1 0 Td 42.063492 Tz (protein ) Tj 60.672269 0 0 60.672269 0 1374.247423 Tm 5.95 0 Td 41.204986 Tz (In ) Tj 0.840582 0 Td 52.192982 Tz (some ) Tj 1.598753 0 Td 49.196256 Tz (embodiments ) Tj 3.329363 0 Td 24.722992 Tz (, ) Tj 0.445014 0 Td 42.120653 Tz (the ) Tj 1.087812 0 Td 43.036319 Tz (invention ) Tj 2.637119 0 Td 43.60861 Tz (provides ) Tj 2.439335 0 Td 41.989843 Tz (nucleic ) Tj 3.049169 0 Td 46.355609 Tz (encoding ) Tj 2.571191 0 Td 41.597415 Tz (nucleic ) Tj 2.126177 0 Td 41.891736 Tz (acid ) Tj 1.368006 0 Td 46.012235 Tz (sequence ) Tj 2.571191 0 Td 30.21699 Tz (is ) Tj 0.74169 0 Td 44.29536 Tz (operably ) Tj 2.472299 0 Td 42.578486 Tz (linked ) Tj 1.862465 0 Td 37.084488 Tz (to ) Tj 0.8241 0 Td 41.204986 Tz (a ) Tj 60.680272 0 0 60.680272 0 1333.177998 Tm 5.322982 0 Td 40.650224 Tz (acids ) Tj 1.417265 0 Td 48.523916 Tz (and ) Tj 1.021749 0 Td 42.298206 Tz (other ) Tj 1.400785 0 Td 42.22954 Tz (reagents ) Tj 2.191816 0 Td 41.199552 Tz (useful ) Tj 1.664462 0 Td 39.36846 Tz (for ) Tj 0.856951 0 Td 45.868834 Tz (genotyping ) Tj 2.916928 0 Td 49.439462 Tz (and ) Tj 0.988789 0 Td 19.226457 Tz (/ ) Tj 0.181278 0 Td 34.33296 Tz (or ) Tj 0.642713 0 Td 36.883408 Tz (select- ) Tj 2.73565 0 Td 47.379484 Tz (promoter ) Tj 2.471973 0 Td 47.608371 Tz (and ) Tj 0.95583 0 Td 19.226457 Tz (/ ) Tj 0.164798 0 Td 38.452915 Tz (or ) Tj 0.659193 0 Td 42.298206 Tz (other ) Tj 1.466704 0 Td 39.931873 Tz (transcription ) Tj 3.312444 0 Td 41.474215 Tz (regulating ) Tj 2.71917 0 Td 44.976177 Tz (elements ) Tj 2.175336 0 Td 19.226457 Tz (. ) Tj 0.379036 0 Td 42.57287 Tz (In ) Tj 62.857143 0 0 62.857143 0 1289.906077 Tm 5.138636 0 Td 40.656566 Tz (ing ) Tj 0.906818 0 Td 38.888889 Tz (plants ) Tj 1.575 0 Td 44.633838 Tz (having ) Tj 1.797727 0 Td 43.308081 Tz (and ) Tj 0.906818 0 Td 18.560606 Tz (/ ) Tj 0.143182 0 Td 38.44697 Tz (or ) Tj 0.620455 0 Td 42.159091 Tz (expressing ) Tj 2.704545 0 Td 39.772727 Tz (a ) Tj 0.413636 0 Td 40.151515 Tz (nucleic ) Tj 1.893182 0 Td 40.435606 Tz (acid ) Tj 1.145455 0 Td 45.075758 Tz (encoding ) Tj 2.529545 0 Td 37.121212 Tz (40 ) Tj 0.843182 0 Td 40.361953 Tz (preferred ) Tj 2.386364 0 Td 48.450413 Tz (embodiments ) Tj 3.181818 0 Td 23.863636 Tz (, ) Tj 0.35 0 Td 39.772727 Tz (the ) Tj 0.906818 0 Td 40.530303 Tz (nucleic ) Tj 1.925 0 Td 41.098485 Tz (acid ) Tj 1.193182 0 Td 44.744318 Tz (sequence ) Tj 2.354545 0 Td 29.166667 Tz (is ) Tj 0.604545 0 Td 38.005051 Tz (stably ) Tj 62.016807 0 0 62.016807 0 1247.902872 Tm 5.208266 0 Td 41.079494 Tz (disease ) Tj 1.983333 0 Td 39.50542 Tz (resistance ) Tj 2.418699 0 Td 13.437218 Tz (, ) Tj 0.386992 0 Td 34.264905 Tz (e.g. ) Tj 0.886856 0 Td 13.437218 Tz (, ) Tj 0.403117 0 Td 47.702123 Tz (Fhbl ) Tj 1.499593 0 Td 41.655375 Tz (or ) Tj 0.773984 0 Td 46.582355 Tz (one ) Tj 1.128726 0 Td 44.342818 Tz (of ) Tj 0.741734 0 Td 40.311653 Tz (the ) Tj 1.015854 0 Td 41.386631 Tz (other ) Tj 1.483469 0 Td 41.079494 Tz (nucleic ) Tj 2.983062 0 Td 40.042909 Tz (integrated ) Tj 2.612195 0 Td 37.62421 Tz (into ) Tj 1.128726 0 Td 40.311653 Tz (the ) Tj 1.048103 0 Td 51.86766 Tz (chromosome ) Tj 3.095935 0 Td 26.874435 Tz (. ) Tj 63.571429 0 0 63.571429 0 1206.808551 Tm 5.080899 0 Td 38.801498 Tz (acids ) Tj 1.38427 0 Td 43.586142 Tz (provided ) Tj 2.265169 0 Td 48.501873 Tz (by ) Tj 0.770787 0 Td 39.325843 Tz (the ) Tj 0.91236 0 Td 41.073658 Tz (invention ) Tj 2.391011 0 Td 44.569288 Tz (having ) Tj 1.793258 0 Td 39.325843 Tz (the ) Tj 0.92809 0 Td 48.501873 Tz (same ) Tj 1.38427 0 Td 39.325843 Tz (or ) Tj 0.676404 0 Td 38.576779 Tz (similar ) Tj 3.397753 0 Td 40.636704 Tz (In ) Tj 0.644944 0 Td 50.468165 Tz (some ) Tj 1.368539 0 Td 47.42935 Tz (embodiments ) Tj 3.303371 0 Td 44.569288 Tz (of ) Tj 0.613483 0 Td 39.325843 Tz (the ) Tj 0.880899 0 Td 39.908448 Tz (invention ) Tj 2.202247 0 Td 23.595506 Tz (, ) Tj 0.283146 0 Td 40.636704 Tz (multiple ) Tj 2.123596 0 Td 40.636704 Tz (copies ) Tj 1.635955 0 Td 44.569288 Tz (of ) Tj 57.857143 0 0 57.857143 0 1165.98619 Tm 5.582716 0 Td 42.921811 Tz (functional ) Tj 2.8 0 Td 40.90535 Tz (characteristics ) Tj 3.698765 0 Td 20.164609 Tz (. ) Tj 0.328395 0 Td 50.699588 Tz (These ) Tj 1.693827 0 Td 44.032922 Tz (nucleic ) Tj 2.05679 0 Td 43.209877 Tz (acids ) Tj 1.503704 0 Td 49.931413 Tz (can ) Tj 1.071605 0 Td 48.971193 Tz (be ) Tj 0.777778 0 Td 43.209877 Tz (useful ) Tj 2.903704 0 Td 43.209877 Tz (a ) Tj 0.518519 0 Td 43.621399 Tz (disease ) Tj 2.074074 0 Td 42.345679 Tz (resistance ) Tj 2.782716 0 Td 44.36214 Tz (conferring ) Tj 2.903704 0 Td 44.032922 Tz (nucleic ) Tj 2.108642 0 Td 44.650206 Tz (acid ) Tj 1.106173 0 Td 14.403292 Tz (, ) Tj 0.380247 0 Td 48.251029 Tz (such ) Tj 1.4 0 Td 40.329218 Tz (as ) Tj 0.760494 0 Td 56.17284 Tz (Fhb1 ) Tj 1.279012 0 Td 25.925926 Tz (, ) Tj 61.836735 0 0 61.836735 0 1124.377492 Tm 5.207261 0 Td 37.733773 Tz (in ) Tj 0.646865 0 Td 40.429043 Tz (a ) Tj 0.420462 0 Td 40.044004 Tz (variety ) Tj 1.875908 0 Td 45.819582 Tz (of ) Tj 0.679208 0 Td 40.429043 Tz (contexts ) Tj 2.021452 0 Td 21.562156 Tz (, ) Tj 0.323432 0 Td 41.926415 Tz (including ) Tj 2.458086 0 Td 39.081408 Tz (as ) Tj 0.663036 0 Td 44.921159 Tz (molecular ) Tj 2.587459 0 Td 45.819582 Tz (markers ) Tj 2.150825 0 Td 38.632197 Tz (for ) Tj 1.940594 0 Td 39.53062 Tz (are ) Tj 0.954125 0 Td 43.124312 Tz (introduced ) Tj 2.813861 0 Td 37.733773 Tz (into ) Tj 1.164356 0 Td 40.429043 Tz (a ) Tj 0.468977 0 Td 40.429043 Tz (plant ) Tj 1.455446 0 Td 37.733773 Tz (in ) Tj 0.69538 0 Td 42.046205 Tz (order ) Tj 1.471617 0 Td 37.733773 Tz (to ) Tj 0.711551 0 Td 40.765952 Tz (increase ) Tj 2.19934 0 Td 43.124312 Tz (expression ) Tj 58.571429 0 0 58.571429 0 1090 Tm 5.514634 0 Td 46.595528 Tz (breeding ) Tj 60 0 0 60 0 1083.618182 Tm 20.716667 0 Td 37.5 Tz (45 ) Tj 0.9 0 Td 39.351852 Tz (levels ) Tj 1.483333 0 Td 11.111111 Tz (. ) Tj 0.283333 0 Td 41.666667 Tz (In ) Tj 0.666667 0 Td 41.666667 Tz (a ) Tj 0.416667 0 Td 40.873016 Tz (variety ) Tj 1.9 0 Td 47.222222 Tz (of ) Tj 0.666667 0 Td 42.283951 Tz (preferred ) Tj 2.45 0 Td 50 Tz (embodiments ) Tj 3.316667 0 Td 25 Tz (, ) Tj 0.366667 0 Td 41.666667 Tz (a ) Tj 0.416667 0 Td 42.063492 Tz (nucleic ) Tj 1.966667 0 Td 43.055556 Tz (acid ) Tj 57.07483 0 0 57.07483 0 1042.621202 Tm 6.32503 0 Td 43.802145 Tz (In ) Tj 0.82348 0 Td 42.133492 Tz (certain ) Tj 2.067461 0 Td 52.828042 Tz (embodiments ) Tj 3.46913 0 Td 26.281287 Tz (, ) Tj 0.490584 0 Td 43.802145 Tz (the ) Tj 1.103814 0 Td 45.424447 Tz (invention ) Tj 2.733254 0 Td 46.722288 Tz (provides ) Tj 2.64565 0 Td 41.716329 Tz (geneti- ) Tj 3.06615 0 Td 49.642431 Tz (of ) Tj 0.770918 0 Td 43.802145 Tz (the ) Tj 1.068772 0 Td 43.802145 Tz (invention ) Tj 2.45292 0 Td 26.281287 Tz (, ) Tj 0.455542 0 Td 48.912396 Tz (such ) Tj 1.43671 0 Td 40.882002 Tz (as ) Tj 0.788439 0 Td 51.102503 Tz (an ) Tj 0.876043 0 Td 51.832539 Tz (Fhbl ) Tj 1.576877 0 Td 44.219309 Tz (nucleic ) Tj 2.155066 0 Td 45.262217 Tz (acid ) Tj 1.103814 0 Td 14.600715 Tz (, ) Tj 0.40298 0 Td 32.121573 Tz (is ) Tj 0.700834 0 Td 45.887962 Tz (stacked ) Tj 59.428571 0 0 59.428571 0 1002.574062 Tm 5.418269 0 Td 38.701923 Tz (cally ) Tj 1.278846 0 Td 28.044872 Tz (- ) Tj 0.084135 0 Td 48.026843 Tz (modified ) Tj 2.439904 0 Td 40.665064 Tz (plants ) Tj 1.632212 0 Td 47.208868 Tz (having ) Tj 1.867788 0 Td 50.130208 Tz (improved ) Tj 2.557692 0 Td 42.467949 Tz (disease ) Tj 1.935096 0 Td 40.665064 Tz (resistance ) Tj 2.490385 0 Td 19.63141 Tz (. ) Tj 0.302885 0 Td 43.469551 Tz (In ) Tj 1.817308 0 Td 44.871795 Tz (and ) Tj 1.009615 0 Td 19.63141 Tz (/ ) Tj 0.084135 0 Td 42.067308 Tz (or ) Tj 0.841346 0 Td 49.85755 Tz (pyramided ) Tj 3.045673 0 Td 46.274038 Tz (with ) Tj 1.480769 0 Td 42.628205 Tz (other ) Tj 1.632212 0 Td 43.269231 Tz (desired ) Tj 2.170673 0 Td 45.99359 Tz (genes ) Tj 1.766827 0 Td 50.480769 Tz (and ) Tj 1.262019 0 Td 42.467949 Tz (genetic ) Tj 60.928571 0 0 60.928571 0 957.98587 Tm 5.30129 0 Td 51.973427 Tz (some ) Tj 1.592028 0 Td 41.578742 Tz (cases ) Tj 1.313013 0 Td 13.677218 Tz (, ) Tj 0.426729 0 Td 42.12583 Tz (these ) Tj 1.592028 0 Td 39.290916 Tz (genetically ) Tj 2.724502 0 Td 27.354435 Tz (- ) Tj 0.180539 0 Td 45.134818 Tz (modified ) Tj 2.478312 0 Td 40.119838 Tz (plants ) Tj 1.772567 0 Td 47.870262 Tz (have ) Tj 1.47714 0 Td 48.554123 Tz (been ) Tj 2.396249 0 Td 34.648951 Tz (traits ) Tj 1.23095 0 Td 21.883548 Tz (, ) Tj 0.344666 0 Td 41.305197 Tz (optionally ) Tj 2.691676 0 Td 42.247406 Tz (including ) Tj 2.494725 0 Td 45.408363 Tz (genes ) Tj 1.608441 0 Td 36.928488 Tz (that ) Tj 1.083236 0 Td 43.311189 Tz (confer ) Tj 1.739742 0 Td 40.21102 Tz (resistance ) Tj 2.609613 0 Td 38.296209 Tz (to ) Tj 0.689332 0 Td 35.560766 Tz (a ) Tj 62.517007 0 0 62.517007 0 917.839133 Tm 5.150598 0 Td 43.721436 Tz (engineered ) Tj 2.863221 0 Td 37.323177 Tz (to ) Tj 0.751795 0 Td 40.716193 Tz (incorporate ) Tj 2.97519 0 Td 31.991295 Tz (a ) Tj 0.511861 0 Td 40.369967 Tz (nucleic ) Tj 1.999456 0 Td 41.322089 Tz (acid ) Tj 1.263656 0 Td 43.98803 Tz (of ) Tj 0.7358 0 Td 39.989119 Tz (the ) Tj 1.023721 0 Td 41.470197 Tz (invention ) Tj 3.471055 0 Td 40.369967 Tz (disease ) Tj 1.935473 0 Td 39.989119 Tz (or ) Tj 0.687813 0 Td 39.989119 Tz (diseases ) Tj 2.175408 0 Td 44.654516 Tz (such ) Tj 1.279652 0 Td 38.656148 Tz (as ) Tj 0.703808 0 Td 62.205296 Tz (FHB ) Tj 1.199674 0 Td 10.663765 Tz (. ) Tj 0.319913 0 Td 45.321001 Tz (For ) Tj 1.023721 0 Td 47.986942 Tz (example ) Tj 1.98346 0 Td 26.659412 Tz (, ) Tj 0.399891 0 Td 39.989119 Tz (a ) Tj 0.447878 0 Td 40.58155 Tz (preferred ) Tj 65.714286 0 0 65.714286 0 874.615715 Tm 4.915217 0 Td 43.115942 Tz (encoding ) Tj 2.252174 0 Td 38.043478 Tz (a ) Tj 0.395652 0 Td 38.405797 Tz (protein ) Tj 1.780435 0 Td 40.942029 Tz (capable ) Tj 1.886957 0 Td 43.115942 Tz (of ) Tj 0.63913 0 Td 39.057971 Tz (conferring ) Tj 2.526087 0 Td 38.768116 Tz (disease ) Tj 1.780435 0 Td 37.282609 Tz (resistance ) Tj 2.282609 0 Td 12.681159 Tz (, ) Tj 0.471739 0 Td 34.23913 Tz (50 ) Tj 0.806522 0 Td 32.246377 Tz (allelic ) Tj 1.552174 0 Td 37.318841 Tz (variant ) Tj 1.765217 0 Td 41.847826 Tz (of ) Tj 0.63913 0 Td 59.178744 Tz (FHB ) Tj 1.126087 0 Td 12.681159 Tz (, ) Tj 0.28913 0 Td 46.15942 Tz (which ) Tj 1.567391 0 Td 43.115942 Tz (can ) Tj 0.943478 0 Td 44.384058 Tz (be ) Tj 0.730435 0 Td 35.76087 Tz (identified ) Tj 2.313043 0 Td 40.57971 Tz (using ) Tj 1.4 0 Td 55.163043 Tz (meth ) Tj 60.357143 0 0 60.357143 0 832.442119 Tm 5.351479 0 Td 35.207101 Tz (e.g. ) Tj 0.911243 0 Td 13.806706 Tz (, ) Tj 0.314793 0 Td 51.775148 Tz (Fhb1 ) Tj 1.242604 0 Td 19.329389 Tz (. ) Tj 0.347929 0 Td 41.420118 Tz (In ) Tj 0.695858 0 Td 53.155819 Tz (some ) Tj 1.457988 0 Td 50.206204 Tz (embodiments ) Tj 3.297041 0 Td 24.852071 Tz (, ) Tj 0.347929 0 Td 41.420118 Tz (the ) Tj 0.927811 0 Td 42.209073 Tz (nucleic ) Tj 1.971598 0 Td 42.800789 Tz (acid ) Tj 1.209467 0 Td 30.374753 Tz (is ) Tj 0.67929 0 Td 40.499671 Tz (opera- ) Tj 2.733728 0 Td 45.101907 Tz (ods ) Tj 1.093491 0 Td 46.942801 Tz (of ) Tj 0.745562 0 Td 36.587771 Tz (this ) Tj 1.159763 0 Td 41.420118 Tz (invention ) Tj 2.286391 0 Td 24.852071 Tz (, ) Tj 0.447337 0 Td 30.374753 Tz (is ) Tj 0.629586 0 Td 49.090511 Tz (pyramided ) Tj 2.899408 0 Td 45.56213 Tz (with ) Tj 1.35858 0 Td 41.972387 Tz (other ) Tj 1.507692 0 Td 45.838264 Tz (genes ) Tj 1.673373 0 Td 58.908613 Tz (con ) Tj 60.075188 0 0 60.075188 0 793.807717 Tm 5.35995 0 Td 39.3026 Tz (tively ) Tj 1.697872 0 Td 46.766792 Tz (coupled ) Tj 2.230538 0 Td 46.469545 Tz (with ) Tj 1.398248 0 Td 41.614518 Tz (a ) Tj 0.51602 0 Td 47.856696 Tz (promoter ) Tj 2.5801 0 Td 49.012655 Tz (and ) Tj 0.998748 0 Td 19.420108 Tz (/ ) Tj 0.083229 0 Td 41.614518 Tz (or ) Tj 0.765707 0 Td 42.724239 Tz (other ) Tj 1.531414 0 Td 40.547479 Tz (transcription ) Tj 4.411139 0 Td 39.456728 Tz (tributing ) Tj 2.347059 0 Td 46.370463 Tz (towards ) Tj 2.197247 0 Td 42.407176 Tz (disease ) Tj 1.997497 0 Td 40.782228 Tz (resistance ) Tj 2.679975 0 Td 41.614518 Tz (or ) Tj 0.71577 0 Td 42.724239 Tz (other ) Tj 1.481477 0 Td 41.614518 Tz (useful ) Tj 1.731164 0 Td 33.291615 Tz (traits ) Tj 1.265081 0 Td 19.420108 Tz (. ) Tj 59.319728 0 0 59.319728 0 751.571338 Tm 5.428211 0 Td 42.425459 Tz (regulating ) Tj 2.781537 0 Td 46.007741 Tz (elements ) Tj 2.191514 0 Td 25.286697 Tz (, ) Tj 0.387729 0 Td 51.697248 Tz (which ) Tj 1.753211 0 Td 48.700306 Tz (can ) Tj 1.062041 0 Td 49.168578 Tz (be ) Tj 0.826032 0 Td 36.525229 Tz (cis ) Tj 0.893463 0 Td 43.549312 Tz (or ) Tj 0.708028 0 Td 39.896789 Tz (trans ) Tj 1.432913 0 Td 47.061353 Tz (with ) Tj 1.314908 0 Td 42.545872 Tz (respect ) Tj 3.708716 0 Td 43.549312 Tz (In ) Tj 0.674312 0 Td 54.085436 Tz (some ) Tj 1.432913 0 Td 50.172018 Tz (methods ) Tj 2.258945 0 Td 47.061353 Tz (provided ) Tj 2.37695 0 Td 51.978211 Tz (by ) Tj 0.758601 0 Td 42.144495 Tz (the ) Tj 0.927179 0 Td 42.144495 Tz (invention ) Tj 2.360092 0 Td 25.286697 Tz (, ) Tj 0.30344 0 Td 49.168578 Tz (an ) Tj 0.724885 0 Td 49.324669 Tz (exogenous ) Tj 59.857143 0 0 59.857143 0 712.335742 Tm 5.379475 0 Td 37.589499 Tz (to ) Tj 0.801909 0 Td 41.76611 Tz (the ) Tj 1.085919 0 Td 42.561655 Tz (protein ) Tj 2.105012 0 Td 47.334924 Tz (encoding ) Tj 2.606205 0 Td 42.163882 Tz (nucleic ) Tj 2.138425 0 Td 43.158313 Tz (acid ) Tj 1.069212 0 Td 11.137629 Tz (. ) Tj 0.451074 0 Td 41.76611 Tz (In ) Tj 0.852029 0 Td 52.903739 Tz (some ) Tj 1.603819 0 Td 42.694246 Tz (preferred ) Tj 3.575179 0 Td 44.550517 Tz (and ) Tj 1.002387 0 Td 19.490851 Tz (/ ) Tj 0.150358 0 Td 36.197295 Tz (or ) Tj 0.668258 0 Td 44.550517 Tz (heterologous ) Tj 3.47494 0 Td 48.031026 Tz (promoter ) Tj 2.25537 0 Td 25.059666 Tz (, ) Tj 0.434368 0 Td 43.158313 Tz (or ) Tj 0.768496 0 Td 42.322991 Tz (other ) Tj 1.50358 0 Td 40.695184 Tz (transcription ) Tj 3.491647 0 Td 51.511535 Tz (regu ) Tj 58.571429 0 0 58.571429 0 668.348437 Tm 5.514634 0 Td 51.736881 Tz (embodiments ) Tj 3.397561 0 Td 25.609756 Tz (, ) Tj 0.341463 0 Td 42.682927 Tz (the ) Tj 0.939024 0 Td 43.495935 Tz (nucleic ) Tj 2.031707 0 Td 43.394309 Tz (acid ) Tj 1.212195 0 Td 32.723577 Tz (is ) Tj 0.597561 0 Td 44.579946 Tz (incorporated ) Tj 3.380488 0 Td 39.126016 Tz (into ) Tj 1.143902 0 Td 42.682927 Tz (a ) Tj 0.443902 0 Td 43.089431 Tz (genetic ) Tj 2.236585 0 Td 36.99187 Tz (55 ) Tj 0.904878 0 Td 40.785908 Tz (latory ) Tj 1.77561 0 Td 48.373984 Tz (element ) Tj 1.997561 0 Td 25.609756 Tz (, ) Tj 0.495122 0 Td 31.300813 Tz (is ) Tj 0.717073 0 Td 45.243902 Tz (introduced ) Tj 3.021951 0 Td 39.837398 Tz (into ) Tj 1.280488 0 Td 42.682927 Tz (a ) Tj 0.563415 0 Td 42.682927 Tz (plant ) Tj 1.587805 0 Td 41.260163 Tz (in ) Tj 0.802439 0 Td 48.373984 Tz (an ) Tj 0.887805 0 Td 45.528455 Tz (operable ) Tj 61.156463 0 0 61.156463 0 626.372599 Tm 5.281535 0 Td 42.695588 Tz (construct ) Tj 2.207453 0 Td 21.802002 Tz (, ) Tj 0.490545 0 Td 45.647942 Tz (such ) Tj 1.389878 0 Td 38.153504 Tz (as ) Tj 0.784872 0 Td 40.878754 Tz (a ) Tj 0.555951 0 Td 39.175473 Tz (cassette ) Tj 2.191101 0 Td 48.146088 Tz (and ) Tj 0.948387 0 Td 19.076752 Tz (/ ) Tj 0.147164 0 Td 38.153504 Tz (or ) Tj 0.752169 0 Td 43.331479 Tz (expression ) Tj 2.877864 0 Td 42.695588 Tz (vector ) Tj 1.831368 0 Td 42.241379 Tz (or ) Tj 1.716908 0 Td 39.743233 Tz (relationship ) Tj 3.041379 0 Td 45.647942 Tz (with ) Tj 1.275417 0 Td 40.878754 Tz (a ) Tj 0.425139 0 Td 47.010567 Tz (gene ) Tj 1.30812 0 Td 43.993326 Tz (capable ) Tj 2.027586 0 Td 46.329255 Tz (of ) Tj 0.670412 0 Td 41.968854 Tz (conferring ) Tj 2.697998 0 Td 41.657397 Tz (disease ) Tj 1.978532 0 Td 44.694105 Tz (resis ) Tj 62.619048 0 0 62.619048 0 583.377393 Tm 5.126236 0 Td 45.247148 Tz (plasmid ) Tj 1.948289 0 Td 10.646388 Tz (. ) Tj 0.255513 0 Td 39.923954 Tz (In ) Tj 0.654753 0 Td 50.570342 Tz (some ) Tj 1.373384 0 Td 40.51542 Tz (preferred ) Tj 2.347529 0 Td 48.150709 Tz (embodiments ) Tj 3.161977 0 Td 23.954373 Tz (, ) Tj 0.335361 0 Td 39.923954 Tz (the ) Tj 0.862357 0 Td 40.684411 Tz (nucleic ) Tj 1.884411 0 Td 41.254753 Tz (acid ) Tj 1.13384 0 Td 30.608365 Tz (is ) Tj 1.612928 0 Td 41.520913 Tz (tance ) Tj 1.293536 0 Td 13.307985 Tz (, ) Tj 0.271483 0 Td 44.581749 Tz (such ) Tj 1.213688 0 Td 38.593156 Tz (as ) Tj 0.638783 0 Td 53.231939 Tz (Fhb1 ) Tj 1.181749 0 Td 23.954373 Tz (, ) Tj 0.319392 0 Td 41.254753 Tz (or ) Tj 0.638783 0 Td 42.205323 Tz (another ) Tj 1.90038 0 Td 40.684411 Tz (nucleic ) Tj 1.868441 0 Td 41.254753 Tz (acid ) Tj 1.117871 0 Td 44.249049 Tz (provided ) Tj 2.251711 0 Td 38.593156 Tz (herein ) Tj 1.469202 0 Td 23.954373 Tz (, ) Tj 56.530612 0 0 56.530612 0 545.667752 Tm 5.713718 0 Td 42.749699 Tz (stably ) Tj 1.786643 0 Td 43.929001 Tz (integrated ) Tj 2.865704 0 Td 41.275572 Tz (into ) Tj 1.238267 0 Td 44.223827 Tz (the ) Tj 1.025993 0 Td 43.634176 Tz (plant ) Tj 1.556679 0 Td 57.490975 Tz (chromosome ) Tj 3.39639 0 Td 23.586041 Tz (. ) Tj 58.571429 0 0 58.571429 0 541.980743 Tm 22.160976 0 Td 42.682927 Tz (so ) Tj 0.836585 0 Td 41.260163 Tz (as ) Tj 0.802439 0 Td 38.414634 Tz (to ) Tj 0.802439 0 Td 43.038618 Tz (increase ) Tj 2.373171 0 Td 45.528455 Tz (expression ) Tj 3.021951 0 Td 48.373984 Tz (of ) Tj 0.819512 0 Td 66.395664 Tz (FHB ) Tj 1.519512 0 Td 40.121951 Tz (resistance ) Tj 2.509756 0 Td 19.918699 Tz (. ) Tj 0.460976 0 Td 44.105691 Tz (In ) Tj 0.836585 0 Td 54.776423 Tz (some ) Tj 62.030075 0 0 62.030075 0 502.800635 Tm 5.819758 0 Td 40.30303 Tz (In ) Tj 0.693212 0 Td 51.050505 Tz (some ) Tj 1.434788 0 Td 48.363636 Tz (embodiments ) Tj 3.208121 0 Td 24.181818 Tz (, ) Tj 0.386909 0 Td 40.30303 Tz (a ) Tj 0.435273 0 Td 39.765657 Tz (plant ) Tj 1.386424 0 Td 44.669192 Tz (provided ) Tj 2.321455 0 Td 49.707071 Tz (by ) Tj 0.789939 0 Td 40.30303 Tz (the ) Tj 0.93503 0 Td 42.094276 Tz (invention ) Tj 3.482182 0 Td 48.363636 Tz (embodiments ) Tj 3.272606 0 Td 18.808081 Tz (, ) Tj 0.370788 0 Td 39.407407 Tz (the ) Tj 0.93503 0 Td 46.348485 Tz (promoter ) Tj 2.418182 0 Td 43.885522 Tz (and ) Tj 0.902788 0 Td 18.808081 Tz (/ ) Tj 0.12897 0 Td 42.989899 Tz (or ) Tj 0.741576 0 Td 38.856255 Tz (transcription ) Tj 3.224242 0 Td 41.377778 Tz (regulatory ) Tj 57.142857 0 0 57.142857 0 460.247029 Tm 5.6525 0 Td 44.236111 Tz (incorporates ) Tj 3.3775 0 Td 43.75 Tz (a ) Tj 0.42 0 Td 44.166667 Tz (nucleic ) Tj 2.0475 0 Td 45.208333 Tz (acid ) Tj 1.26 0 Td 48.854167 Tz (sequence ) Tj 2.5025 0 Td 45.694444 Tz (not ) Tj 0.98 0 Td 44.236111 Tz (native ) Tj 1.7325 0 Td 40.833333 Tz (to ) Tj 0.665 0 Td 46.666667 Tz (plant ) Tj 1.2425 0 Td 29.166667 Tz (, ) Tj 0.385 0 Td 37.1875 Tz (e.g. ) Tj 0.9625 0 Td 14.583333 Tz (, ) Tj 0.56 0 Td 37.916667 Tz (60 ) Tj 0.91 0 Td 47.395833 Tz (elements ) Tj 2.52 0 Td 42.777778 Tz (are ) Tj 0.9975 0 Td 49.166667 Tz (induced ) Tj 2.2575 0 Td 52.5 Tz (by ) Tj 0.8575 0 Td 43.75 Tz (a ) Tj 0.49 0 Td 44.583333 Tz (disease ) Tj 2.1 0 Td 38.5 Tz (state ) Tj 1.3825 0 Td 45.208333 Tz (or ) Tj 0.735 0 Td 52.5 Tz (by ) Tj 0.84 0 Td 47.395833 Tz (presence ) Tj 2.5025 0 Td 49.583333 Tz (of ) Tj 0.7525 0 Td 43.75 Tz (a ) Tj 60.31746 0 0 60.31746 0 418.677953 Tm 5.338421 0 Td 48.355263 Tz (an ) Tj 0.746053 0 Td 48.201754 Tz (exogenous ) Tj 2.801842 0 Td 49.046053 Tz (Fhbl ) Tj 1.409211 0 Td 42.236842 Tz (nucleic ) Tj 1.972895 0 Td 42.138158 Tz (acid ) Tj 1.177105 0 Td 44.210526 Tz (derived ) Tj 2.022632 0 Td 49.046053 Tz (from ) Tj 1.359474 0 Td 43.815789 Tz (another ) Tj 2.072368 0 Td 43.105263 Tz (plant ) Tj 1.276579 0 Td 24.868421 Tz (, ) Tj 1.309737 0 Td 45.9375 Tz (pathogen ) Tj 2.238158 0 Td 27.631579 Tz (, ) Tj 0.414474 0 Td 35.921053 Tz (e.g. ) Tj 0.895263 0 Td 16.578947 Tz (, ) Tj 0.364737 0 Td 40.526316 Tz (the ) Tj 0.961579 0 Td 64.473684 Tz (FHB ) Tj 1.392632 0 Td 45.9375 Tz (pathogen ) Tj 2.238158 0 Td 27.631579 Tz (. ) Tj 59.87013 0 0 59.87013 0 375.85724 Tm 5.411714 0 Td 38.045312 Tz (strain ) Tj 1.686985 0 Td 43.148952 Tz (or ) Tj 0.851844 0 Td 39.321222 Tz (cultivar ) Tj 1.887419 0 Td 19.486623 Tz (. ) Tj 0.467679 0 Td 41.75705 Tz (In ) Tj 0.851844 0 Td 52.892263 Tz (some ) Tj 1.620174 0 Td 50.867679 Tz (embodiments ) Tj 3.323861 0 Td 25.05423 Tz (, ) Tj 0.517787 0 Td 41.75705 Tz (a ) Tj 0.584599 0 Td 41.75705 Tz (plant ) Tj 1.586768 0 Td 47.324657 Tz (of ) Tj 0.835141 0 Td 41.75705 Tz (the ) Tj 2.655748 0 Td 43.148952 Tz (In ) Tj 0.734924 0 Td 53.588214 Tz (some ) Tj 1.503254 0 Td 51.120752 Tz (embodiments ) Tj 3.357267 0 Td 25.05423 Tz (, ) Tj 0.350759 0 Td 44.540853 Tz (expression ) Tj 2.872885 0 Td 47.324657 Tz (of ) Tj 0.718221 0 Td 41.75705 Tz (a ) Tj 0.450976 0 Td 42.221017 Tz (native ) Tj 1.737093 0 Td 49.412509 Tz (Fhbl ) Tj 1.469848 0 Td 48.716558 Tz (gene ) Tj 63.174603 0 0 63.174603 0 332.442904 Tm 5.112814 0 Td 41.331658 Tz (invention ) Tj 2.40603 0 Td 40.232412 Tz (incorporates ) Tj 3.086683 0 Td 41.196366 Tz (modifications ) Tj 3.403266 0 Td 36.934673 Tz (to ) Tj 0.648995 0 Td 29.020101 Tz (its ) Tj 0.74397 0 Td 55.40201 Tz (own ) Tj 1.171357 0 Td 40.012563 Tz (native ) Tj 1.646231 0 Td 45.508794 Tz (gene ) Tj 2.311055 0 Td 29.020101 Tz (is ) Tj 0.712312 0 Td 44.472362 Tz (induced ) Tj 2.200251 0 Td 40.89196 Tz (or ) Tj 0.823116 0 Td 46.168342 Tz (enhanced ) Tj 2.532663 0 Td 48.806533 Tz (by ) Tj 0.93392 0 Td 39.572864 Tz (a ) Tj 0.569849 0 Td 43.79397 Tz (technology ) Tj 2.96005 0 Td 38.913317 Tz (referred ) Tj 2.184422 0 Td 36.934673 Tz (to ) Tj 0.807286 0 Td 38.253769 Tz (as ) Tj 60 0 0 60 0 293.712406 Tm 5.383333 0 Td 47.222222 Tz (encoding ) Tj 2.416667 0 Td 42.063492 Tz (disease ) Tj 1.916667 0 Td 40.833333 Tz (resistance ) Tj 2.583333 0 Td 38.194444 Tz (that ) Tj 1.083333 0 Td 47.619048 Tz (enhance ) Tj 2.166667 0 Td 41.666667 Tz (or ) Tj 0.633333 0 Td 49.537037 Tz (modify ) Tj 1.933333 0 Td 41.319444 Tz (function ) Tj 2.116667 0 Td 19.444444 Tz (. ) Tj 1.383333 0 Td 27.777778 Tz (" ) Tj 0.4 0 Td 46.944444 Tz (endogenous ) Tj 3.05 0 Td 47.916667 Tz (gene ) Tj 1.4 0 Td 40 Tz (activation ) Tj 2.466667 0 Td 33.333333 Tz ( ) Tj 0.466667 0 Td 27.777778 Tz (\( ) Tj 0.283333 0 Td 62.962963 Tz (EGA ) Tj 1.283333 0 Td 27.777778 Tz (\) ) Tj 0.05 0 Td 27.777778 Tz (. ) Tj 0.433333 0 Td 70.37037 Tz (EGA ) Tj 1.45 0 Td 47.222222 Tz (can ) Tj 1.05 0 Td 47.222222 Tz (be ) Tj 0.833333 0 Td 58.888889 Tz (accom ) Tj 61.428571 0 0 61.428571 0 253.792208 Tm 5.25814 0 Td 47.028424 Tz (For ) Tj 1.155814 0 Td 48.837209 Tz (example ) Tj 2.018605 0 Td 27.131783 Tz (, ) Tj 0.488372 0 Td 42.868217 Tz (techniques ) Tj 2.913953 0 Td 39.793282 Tz (for ) Tj 1.025581 0 Td 72.351421 Tz (DNA ) Tj 1.595349 0 Td 39.534884 Tz (editing ) Tj 1.709302 0 Td 13.565891 Tz (, ) Tj 0.455814 0 Td 44.767442 Tz (such ) Tj 1.4 0 Td 39.341085 Tz (as ) Tj 0.830233 0 Td 33.100775 Tz (site- ) Tj 1.416279 0 Td 33.914729 Tz (65 ) Tj 0.830233 0 Td 41.860465 Tz (plished ) Tj 1.790698 0 Td 13.565891 Tz (, ) Tj 0.325581 0 Td 38.888889 Tz (for ) Tj 0.895349 0 Td 47.286822 Tz (example ) Tj 2.034884 0 Td 27.131783 Tz (, ) Tj 0.35814 0 Td 50.193798 Tz (by ) Tj 0.797674 0 Td 51.007752 Tz (means ) Tj 1.75814 0 Td 46.124031 Tz (of ) Tj 0.7 0 Td 40.697674 Tz (a ) Tj 0.439535 0 Td 42.50646 Tz (vector ) Tj 1.725581 0 Td 45.310078 Tz (comprising ) Tj 2.930233 0 Td 47.932817 Tz (one ) Tj 59.714286 0 0 59.714286 0 211.271669 Tm 5.409091 0 Td 41.866029 Tz (directed ) Tj 2.210526 0 Td 46.686965 Tz (mutagenesis ) Tj 3.332536 0 Td 43.261563 Tz (or ) Tj 0.736842 0 Td 59.542796 Tz (CRISPR ) Tj 2.177033 0 Td 13.955343 Tz (, ) Tj 0.351675 0 Td 47.448166 Tz (can ) Tj 1.055024 0 Td 48.8437 Tz (be ) Tj 0.803828 0 Td 48.145933 Tz (used ) Tj 1.356459 0 Td 39.07496 Tz (to ) Tj 0.703349 0 Td 49.774056 Tz (modify ) Tj 2.043062 0 Td 41.866029 Tz (a ) Tj 1.523923 0 Td 43.261563 Tz (or ) Tj 0.753589 0 Td 53.030303 Tz (more ) Tj 1.523923 0 Td 42.703349 Tz (regulatory ) Tj 2.863636 0 Td 45.897572 Tz (sequences ) Tj 2.763158 0 Td 41.866029 Tz (functional ) Tj 2.779904 0 Td 40.470494 Tz (in ) Tj 0.720096 0 Td 41.866029 Tz (the ) Tj 1.004785 0 Td 41.866029 Tz (plant ) Tj 1.507177 0 Td 46.052632 Tz (with ) Tj 60 0 0 60 0 169.963061 Tm 5.366667 0 Td 47.916667 Tz (gene ) Tj 1.35 0 Td 37.5 Tz (like ) Tj 1.1 0 Td 53.472222 Tz (Fhb1 ) Tj 1.266667 0 Td 25 Tz (, ) Tj 0.35 0 Td 43.055556 Tz (or ) Tj 0.683333 0 Td 47.222222 Tz (an ) Tj 0.766667 0 Td 49.305556 Tz (Fhbi ) Tj 1.433333 0 Td 52.777778 Tz (homologue ) Tj 2.766667 0 Td 27.777778 Tz (, ) Tj 0.383333 0 Td 43.055556 Tz (or ) Tj 0.683333 0 Td 47.222222 Tz (an ) Tj 0.766667 0 Td 35.31746 Tz (allelic ) Tj 1.666667 0 Td 40.873016 Tz (variant ) Tj 3 0 Td 42.063492 Tz (respect ) Tj 2.133333 0 Td 37.5 Tz (to ) Tj 0.85 0 Td 51.111111 Tz (which ) Tj 1.9 0 Td 43.518519 Tz (increased ) Tj 2.716667 0 Td 44.444444 Tz (expression ) Tj 3.033333 0 Td 31.944444 Tz (is ) Tj 0.783333 0 Td 42.460317 Tz (desired ) Tj 1.833333 0 Td 11.111111 Tz (. ) Tj 0.5 0 Td 50.694444 Tz (Such ) Tj ET Q endstream endobj 189 0 obj << /Length 1 >> stream q endstream endobj 190 0 obj << /Length 53687 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 54.285714 0 0 54.285714 0 2971 Tm 13.760526 0 Td 67.54386 Tz (21 ) Tj 54.285714 0 0 54.285714 0 2971 Tm 31.702632 0 Td 70.614035 Tz (22 ) Tj 57.894737 0 0 57.894737 0 2915.340132 Tm 5.561818 0 Td 44.045455 Tz (regulatory ) Tj 2.988182 0 Td 47.340067 Tz (sequences ) Tj 2.884545 0 Td 61.414141 Tz (may ) Tj 1.416364 0 Td 50.378788 Tz (be ) Tj 0.639091 0 Td 14.393939 Tz (, ) Tj 0.449091 0 Td 41.262626 Tz (for ) Tj 1.053636 0 Td 50.17316 Tz (example ) Tj 2.141818 0 Td 28.787879 Tz (, ) Tj 0.483636 0 Td 47.979798 Tz (promoters ) Tj 2.936364 0 Td 44.621212 Tz (or ) Tj 1.848182 0 Td 39.343434 Tz (ers ) Tj 1.019091 0 Td 52.969697 Tz (which ) Tj 1.9 0 Td 49.89899 Tz (sometimes ) Tj 3.005455 0 Td 50.538721 Tz (recombine ) Tj 3.04 0 Td 44.415584 Tz (leading ) Tj 2.159091 0 Td 40.30303 Tz (to ) Tj 0.811818 0 Td 39.480519 Tz (failure ) Tj 1.969091 0 Td 48.939394 Tz (of ) Tj 0.794545 0 Td 44.141414 Tz (the ) Tj 60.902256 0 0 60.902256 0 2873.577874 Tm 5.30358 0 Td 45.610425 Tz (enhancers ) Tj 2.446543 0 Td 19.156379 Tz (. ) Tj 0.311975 0 Td 51.083676 Tz (The ) Tj 1.100123 0 Td 41.87037 Tz (regulatory ) Tj 2.709259 0 Td 45.838477 Tz (sequence ) Tj 2.380864 0 Td 57.469136 Tz (may ) Tj 1.215062 0 Td 43.786008 Tz (then ) Tj 1.198642 0 Td 47.890947 Tz (be ) Tj 0.755309 0 Td 43.786008 Tz (introduced ) Tj 3.858642 0 Td 44.470165 Tz (breeding ) Tj 2.348025 0 Td 50.96965 Tz (programs ) Tj 2.364444 0 Td 19.156379 Tz (. ) Tj 0.311975 0 Td 51.995885 Tz (The ) Tj 1.165802 0 Td 48.575103 Tz (Fhbl ) Tj 1.461358 0 Td 47.20679 Tz (gene ) Tj 1.36284 0 Td 46.522634 Tz (can ) Tj 1.034444 0 Td 47.890947 Tz (be ) Tj 0.771728 0 Td 48.95519 Tz (pyramided ) Tj 2.840617 0 Td 45.154321 Tz (with ) Tj 59.357143 0 0 59.357143 0 2830.10133 Tm 5.441637 0 Td 39.310068 Tz (into ) Tj 1.128761 0 Td 42.11793 Tz (the ) Tj 0.943442 0 Td 42.920176 Tz (desired ) Tj 1.971119 0 Td 42.679503 Tz (locus ) Tj 1.482551 0 Td 47.733654 Tz (of ) Tj 0.673887 0 Td 42.11793 Tz (the ) Tj 0.943442 0 Td 54.285332 Tz (genome ) Tj 2.122744 0 Td 51.945447 Tz (by ) Tj 0.791817 0 Td 51.664661 Tz (homologous ) Tj 3.318893 0 Td 48.201631 Tz (recom- ) Tj 3.032491 0 Td 42.679503 Tz (other ) Tj 1.499398 0 Td 42.11793 Tz (native ) Tj 1.752106 0 Td 41.275572 Tz (resistance ) Tj 2.712395 0 Td 46.610509 Tz (genes ) Tj 1.634176 0 Td 37.906137 Tz (to ) Tj 0.724428 0 Td 48.535901 Tz (enhance ) Tj 2.257521 0 Td 42.11793 Tz (the ) Tj 1.01083 0 Td 39.310068 Tz (level ) Tj 1.43201 0 Td 47.733654 Tz (of ) Tj 0.724428 0 Td 46.610509 Tz (resis ) Tj 61.360544 0 0 61.360544 0 2789.2514 Tm 5.247672 0 Td 41.42184 Tz (bination ) Tj 2.03714 0 Td 13.580931 Tz (, ) Tj 0.260754 0 Td 41.42184 Tz (thus ) Tj 1.18969 0 Td 43.798503 Tz (operably ) Tj 2.281596 0 Td 40.354767 Tz (linking ) Tj 1.857871 0 Td 40.742794 Tz (the ) Tj 0.896341 0 Td 41.55765 Tz (regulatory ) Tj 2.689024 0 Td 45.49612 Tz (sequence ) Tj 2.346785 0 Td 45.49612 Tz (with ) Tj 2.314191 0 Td 42.372506 Tz (tance ) Tj 1.483038 0 Td 39.384701 Tz (in ) Tj 0.651885 0 Td 48.348115 Tz (wheat ) Tj 1.646009 0 Td 39.233801 Tz (cultivars ) Tj 2.118625 0 Td 19.013304 Tz (. ) Tj 0.325942 0 Td 40.742794 Tz (In ) Tj 0.684479 0 Td 41.42184 Tz (addition ) Tj 2.020843 0 Td 13.580931 Tz (, ) Tj 0.309645 0 Td 42.100887 Tz (multiple ) Tj 2.232705 0 Td 42.100887 Tz (copies ) Tj 1.743792 0 Td 46.175166 Tz (of ) Tj 0.668182 0 Td 41.648189 Tz (the ) Tj 57.142857 0 0 57.142857 0 2750.625919 Tm 5.6175 0 Td 43.75 Tz (the ) Tj 1.1725 0 Td 50.3125 Tz (gene ) Tj 1.2425 0 Td 20.416667 Tz (, ) Tj 0.5075 0 Td 43.75 Tz (the ) Tj 1.1725 0 Td 46.375 Tz (expression ) Tj 3.1675 0 Td 48.125 Tz (of ) Tj 0.875 0 Td 53.666667 Tz (which ) Tj 1.9775 0 Td 33.541667 Tz (is ) Tj 0.7875 0 Td 39.375 Tz (to ) Tj 0.8575 0 Td 51.041667 Tz (be ) Tj 0.9975 0 Td 49.166667 Tz (induced ) Tj 2.4325 0 Td 45.208333 Tz (or ) Tj 1.085 0 Td 32.083333 Tz (5 ) Tj 0.805 0 Td 48.416667 Tz (genes ) Tj 1.6975 0 Td 50.555556 Tz (can ) Tj 1.12 0 Td 49.583333 Tz (be ) Tj 0.84 0 Td 46.375 Tz (introduced ) Tj 2.9925 0 Td 53.958333 Tz (by ) Tj 0.8925 0 Td 44.810606 Tz (appropriate ) Tj 3.185 0 Td 47.395833 Tz (breeding ) Tj 2.5375 0 Td 40.25 Tz (strategies ) Tj 57.563025 0 0 57.563025 0 2705.532067 Tm 5.611241 0 Td 50.6691 Tz (enhanced ) Tj 2.466861 0 Td 20.26764 Tz (. ) Tj 0.364818 0 Td 44.878345 Tz (In ) Tj 0.781752 0 Td 55.012165 Tz (some ) Tj 1.563504 0 Td 44.074074 Tz (preferred ) Tj 2.605839 0 Td 51.590356 Tz (embodiments ) Tj 3.474453 0 Td 26.058394 Tz (, ) Tj 0.416934 0 Td 43.430657 Tz (a ) Tj 0.486423 0 Td 45.360908 Tz (vector ) Tj 1.84146 0 Td 43.91322 Tz (useful ) Tj 2.901168 0 Td 39.087591 Tz (to ) Tj 0.747007 0 Td 43.430657 Tz (increase ) Tj 2.327883 0 Td 43.430657 Tz (the ) Tj 1.007591 0 Td 42.562044 Tz (resistance ) Tj 2.796934 0 Td 40.53528 Tz (in ) Tj 0.694891 0 Td 43.430657 Tz (plants ) Tj 1.528759 0 Td 28.953771 Tz (. ) Tj 60.357143 0 0 60.357143 0 2665.737484 Tm 5.351479 0 Td 39.579224 Tz (for ) Tj 1.076923 0 Td 69.953978 Tz (EGA ) Tj 1.590533 0 Td 42.110454 Tz (includes ) Tj 2.402367 0 Td 40.499671 Tz (targeting ) Tj 2.584615 0 Td 45.408722 Tz (sequences ) Tj 2.849704 0 Td 45.031103 Tz (corresponding ) Tj 3.876923 0 Td 38.658777 Tz (to ) Tj 2.369231 0 Td 42.800789 Tz (In ) Tj 0.646154 0 Td 42.524655 Tz (other ) Tj 1.408284 0 Td 49.955173 Tz (embodiments ) Tj 3.330178 0 Td 24.852071 Tz (, ) Tj 0.281657 0 Td 41.420118 Tz (the ) Tj 0.911243 0 Td 42.954197 Tz (invention ) Tj 2.452071 0 Td 43.836292 Tz (provides ) Tj 2.269822 0 Td 49.309665 Tz (methods ) Tj 2.236686 0 Td 40.499671 Tz (for ) Tj 61.428571 0 0 61.428571 0 2622.700405 Tm 5.24186 0 Td 41.036822 Tz (portions ) Tj 2.246512 0 Td 44.767442 Tz (of ) Tj 0.716279 0 Td 40.697674 Tz (the ) Tj 0.976744 0 Td 47.751938 Tz (endogenous ) Tj 3.14186 0 Td 46.802326 Tz (gene ) Tj 1.383721 0 Td 45.445736 Tz (such ) Tj 1.318605 0 Td 37.984496 Tz (that ) Tj 0.895349 0 Td 24.418605 Tz (, ) Tj 0.406977 0 Td 36.899225 Tz (after ) Tj 1.334884 0 Td 40.697674 Tz (a ) Tj 0.52093 0 Td 38.662791 Tz (step ) Tj 1.188372 0 Td 46.124031 Tz (of ) Tj 1.725581 0 Td 43.410853 Tz (using ) Tj 1.709302 0 Td 40.697674 Tz (genetic ) Tj 2.1 0 Td 46.124031 Tz (markers ) Tj 2.344186 0 Td 46.124031 Tz (of ) Tj 0.862791 0 Td 40.697674 Tz (the ) Tj 1.139535 0 Td 42.204996 Tz (invention ) Tj 2.669767 0 Td 38.888889 Tz (for ) Tj 1.074419 0 Td 45.03876 Tz (genotyping ) Tj 61.804511 0 0 61.804511 0 2583.971464 Tm 5.209976 0 Td 49.618816 Tz (homologous ) Tj 3.155109 0 Td 43.976543 Tz (recombination ) Tj 3.46253 0 Td 24.270073 Tz (, ) Tj 0.339781 0 Td 40.450122 Tz (the ) Tj 0.889903 0 Td 41.259124 Tz (regulatory ) Tj 2.669708 0 Td 45.506387 Tz (sequence ) Tj 2.346107 0 Td 38.427616 Tz (will ) Tj 1.100243 0 Td 47.191809 Tz (be ) Tj 1.795985 0 Td 39.55123 Tz (plants ) Tj 1.391484 0 Td 26.966748 Tz (, ) Tj 0.388321 0 Td 40.450122 Tz (preferably ) Tj 2.653528 0 Td 40.450122 Tz (so ) Tj 0.679562 0 Td 40.450122 Tz (as ) Tj 0.679562 0 Td 37.753447 Tz (to ) Tj 0.647202 0 Td 37.753447 Tz (identify ) Tj 2.071046 0 Td 38.652338 Tz (plants ) Tj 1.585645 0 Td 44.94458 Tz (having ) Tj 1.779805 0 Td 32.360097 Tz (a ) Tj 0.453041 0 Td 45.843471 Tz (genotype ) Tj 68.571429 0 0 68.571429 0 2540.738397 Tm 4.710417 0 Td 37.019231 Tz (appropriately ) Tj 3.10625 0 Td 36.458333 Tz (targeted ) Tj 1.954167 0 Td 32.8125 Tz (to ) Tj 0.627083 0 Td 39.236111 Tz (provide ) Tj 1.866667 0 Td 43.75 Tz (endogenous ) Tj 2.829167 0 Td 41.927083 Tz (gene ) Tj 1.239583 0 Td 34.375 Tz (activa- ) Tj 1.8375 0 Td 30.381944 Tz (10 ) Tj 0.729167 0 Td 40.972222 Tz (capable ) Tj 1.808333 0 Td 41.319444 Tz (of ) Tj 0.583333 0 Td 37.430556 Tz (conferring ) Tj 2.40625 0 Td 41.015625 Tz (enhances ) Tj 2.129167 0 Td 37.152778 Tz (disease ) Tj 1.691667 0 Td 35.729167 Tz (resistance ) Tj 2.31875 0 Td 34.635417 Tz (relative ) Tj 1.8375 0 Td 23.090278 Tz (to ) Tj 48.571429 0 0 48.571429 0 2502 Tm 6.608824 0 Td 52.328431 Tz (tion ) Tj 1.255882 0 Td 20.588235 Tz (. ) Tj 61.428571 0 0 61.428571 0 2496.862069 Tm 21.113953 0 Td 40.697674 Tz (a ) Tj 0.488372 0 Td 40.310078 Tz (control ) Tj 1.937209 0 Td 44.496124 Tz (plant ) Tj 1.172093 0 Td 27.131783 Tz (. ) Tj 0.423256 0 Td 42.054264 Tz (In ) Tj 0.748837 0 Td 51.550388 Tz (some ) Tj 1.497674 0 Td 49.083862 Tz (embodiments ) Tj 3.223256 0 Td 24.418605 Tz (, ) Tj 0.439535 0 Td 45.445736 Tz (such ) Tj 1.318605 0 Td 45.310078 Tz (genotyping ) Tj 2.962791 0 Td 31.20155 Tz (is ) Tj 60 0 0 60 0 2456.630086 Tm 6.016667 0 Td 41.666667 Tz (In ) Tj 0.65 0 Td 53.472222 Tz (some ) Tj 1.433333 0 Td 50 Tz (embodiments ) Tj 3.316667 0 Td 25 Tz (, ) Tj 0.3 0 Td 42.592593 Tz (the ) Tj 0.916667 0 Td 43.209877 Tz (invention ) Tj 2.466667 0 Td 44.097222 Tz (provides ) Tj 2.266667 0 Td 50 Tz (methods ) Tj 2.266667 0 Td 39.814815 Tz (for ) Tj 1.966667 0 Td 47.916667 Tz (used ) Tj 1.283333 0 Td 40.740741 Tz (for ) Tj 0.85 0 Td 45.138889 Tz (breeding ) Tj 2.333333 0 Td 49.305556 Tz (improved ) Tj 2.516667 0 Td 42.063492 Tz (disease ) Tj 1.816667 0 Td 25 Tz (- ) Tj 0.166667 0 Td 40.833333 Tz (resistance ) Tj 2.616667 0 Td 38.194444 Tz (into ) Tj 1.1 0 Td 41.666667 Tz (a ) Tj 0.383333 0 Td 41.666667 Tz (plant ) Tj 1.4 0 Td 47.222222 Tz (of ) Tj 61.632653 0 0 61.632653 0 2415.006862 Tm 5.224503 0 Td 39.403974 Tz (editing ) Tj 1.849669 0 Td 40.562914 Tz (the ) Tj 0.924834 0 Td 52.731788 Tz (genome ) Tj 2.093046 0 Td 45.971302 Tz (of ) Tj 0.681457 0 Td 40.562914 Tz (a ) Tj 0.438079 0 Td 40.022075 Tz (plant ) Tj 1.379139 0 Td 36.506623 Tz (to ) Tj 0.665232 0 Td 47.516556 Tz (improve ) Tj 2.190397 0 Td 40.1766 Tz (disease ) Tj 1.833444 0 Td 21.633554 Tz (- ) Tj 0.194702 0 Td 38.399558 Tz (resistance ) Tj 3.553311 0 Td 37.85872 Tz (interest ) Tj 1.736093 0 Td 24.337748 Tz (, ) Tj 0.340728 0 Td 43.267108 Tz (using ) Tj 1.47649 0 Td 40.562914 Tz (a ) Tj 0.405629 0 Td 48.429661 Tz (methodology ) Tj 3.39106 0 Td 45.295254 Tz (such ) Tj 1.249338 0 Td 37.85872 Tz (as ) Tj 0.632781 0 Td 48.224798 Tz (marker ) Tj 1.882119 0 Td 39.210817 Tz (assisted ) Tj 2.141722 0 Td 43.807947 Tz (selec ) Tj 60 0 0 60 0 2374.930573 Tm 5.366667 0 Td 43.209877 Tz (including ) Tj 2.583333 0 Td 47.916667 Tz (gene ) Tj 1.4 0 Td 40.873016 Tz (editing ) Tj 1.95 0 Td 44.166667 Tz (techniques ) Tj 2.9 0 Td 47.222222 Tz (based ) Tj 1.666667 0 Td 50 Tz (on ) Tj 0.85 0 Td 59.259259 Tz (CRISPR ) Tj 2.433333 0 Td 39.444444 Tz (tech- ) Tj 2.45 0 Td 40.277778 Tz (tion ) Tj 1.2 0 Td 30.555556 Tz (\( ) Tj 0.116667 0 Td 76.851852 Tz (MAS ) Tj 1.45 0 Td 27.777778 Tz (\) ) Tj 0.116667 0 Td 27.777778 Tz (. ) Tj 0.416667 0 Td 48.888889 Tz (These ) Tj 1.683333 0 Td 49.603175 Tz (methods ) Tj 2.333333 0 Td 47.222222 Tz (can ) Tj 1.05 0 Td 48.611111 Tz (be ) Tj 0.8 0 Td 47.222222 Tz (used ) Tj 1.333333 0 Td 38.888889 Tz (to ) Tj 0.716667 0 Td 48.809524 Tz (improve ) Tj 2.283333 0 Td 61.805556 Tz (Fhb1 ) Tj 58.571429 0 0 58.571429 0 2330.917488 Tm 5.497561 0 Td 47.425474 Tz (nology ) Tj 1.707317 0 Td 28.455285 Tz (, ) Tj 0.392683 0 Td 39.837398 Tz (as ) Tj 0.7 0 Td 45.212285 Tz (described ) Tj 2.629268 0 Td 50.081301 Tz (above ) Tj 1.570732 0 Td 11.382114 Tz (. ) Tj 0.307317 0 Td 42.682927 Tz (In ) Tj 0.717073 0 Td 54.776423 Tz (some ) Tj 1.519512 0 Td 51.736881 Tz (embodiments ) Tj 3.397561 0 Td 25.609756 Tz (, ) Tj 0.392683 0 Td 42.682927 Tz (a ) Tj 0.443902 0 Td 43.157182 Tz (native ) Tj 1.997561 0 Td 34.146341 Tz (15 ) Tj 0.870732 0 Td 45.212285 Tz (conferred ) Tj 2.612195 0 Td 43.495935 Tz (disease ) Tj 1.997561 0 Td 41.829268 Tz (resistance ) Tj 2.560976 0 Td 14.227642 Tz (, ) Tj 0.307317 0 Td 40.785908 Tz (for ) Tj 0.921951 0 Td 50.406504 Tz (example ) Tj 2.082927 0 Td 28.455285 Tz (, ) Tj 0.409756 0 Td 42.682927 Tz (or ) Tj 0.7 0 Td 40.785908 Tz (for ) Tj 0.921951 0 Td 43.394309 Tz (stacking ) Tj 2.287805 0 Td 44.105691 Tz (or ) Tj 62.184874 0 0 62.184874 0 2290.527584 Tm 5.194189 0 Td 41.734234 Tz (disease ) Tj 1.817162 0 Td 21.441441 Tz (- ) Tj 0.192973 0 Td 38.058559 Tz (resistance ) Tj 2.540811 0 Td 46.233108 Tz (gene ) Tj 1.382973 0 Td 30.822072 Tz (is ) Tj 0.643243 0 Td 40.202703 Tz (edited ) Tj 1.704595 0 Td 36.182432 Tz (to ) Tj 0.723649 0 Td 47.094595 Tz (improve ) Tj 2.267432 0 Td 38.141026 Tz (functionality ) Tj 3.007162 0 Td 26.801802 Tz (. ) Tj 1.350811 0 Td 46.099099 Tz (pyramiding ) Tj 3.167973 0 Td 47.238176 Tz (enhanced ) Tj 2.669459 0 Td 50.923423 Tz (Fhb1 ) Tj 1.318649 0 Td 21.441441 Tz (- ) Tj 0.14473 0 Td 41.691692 Tz (conferred ) Tj 2.669459 0 Td 40.585586 Tz (disease ) Tj 2.106622 0 Td 39.666667 Tz (resistance ) Tj 62.049689 0 0 62.049689 0 2247.955906 Tm 5.205506 0 Td 46.557669 Tz (For ) Tj 0.983083 0 Td 47.964631 Tz (example ) Tj 1.982282 0 Td 26.860194 Tz (, ) Tj 0.370671 0 Td 40.29029 Tz (a ) Tj 0.402903 0 Td 40.73796 Tz (native ) Tj 1.627728 0 Td 46.333834 Tz (gene ) Tj 1.305405 0 Td 44.990824 Tz (such ) Tj 1.240941 0 Td 38.947281 Tz (as ) Tj 0.660761 0 Td 40.29029 Tz (a ) Tj 0.419019 0 Td 30.083417 Tz (first ) Tj 1.07978 0 Td 47.676844 Tz (Fhbl ) Tj 1.385986 0 Td 35.813591 Tz (allele ) Tj 1.466567 0 Td 45.662329 Tz (can ) Tj 0.966967 0 Td 47.005339 Tz (be ) Tj 1.788889 0 Td 44.990824 Tz (with ) Tj 1.289289 0 Td 40.827494 Tz (other ) Tj 1.434334 0 Td 41.441441 Tz (desired ) Tj 1.95005 0 Td 44.050717 Tz (genes ) Tj 1.563263 0 Td 48.348348 Tz (and ) Tj 0.950851 0 Td 18.802135 Tz (/ ) Tj 0.145045 0 Td 37.604271 Tz (or ) Tj 0.628529 0 Td 33.575242 Tz (traits ) Tj 1.208709 0 Td 18.802135 Tz (. ) Tj 56.616541 0 0 56.616541 0 2207.020471 Tm 5.705046 0 Td 44.647337 Tz (edited ) Tj 1.748606 0 Td 39.741036 Tz (to ) Tj 0.671182 0 Td 45.227172 Tz (incorporate ) Tj 3.143958 0 Td 52.006788 Tz (one ) Tj 1.112749 0 Td 44.156707 Tz (or ) Tj 0.671182 0 Td 55.931828 Tz (more ) Tj 1.518991 0 Td 44.156707 Tz (genetic ) Tj 2.031208 0 Td 42.979194 Tz (variations ) Tj 2.773041 0 Td 50.633023 Tz (found ) Tj 1.660292 0 Td 41.212926 Tz (to ) Tj 2.525764 0 Td 45.628597 Tz (In ) Tj 0.671182 0 Td 45.838867 Tz (various ) Tj 2.101859 0 Td 52.988048 Tz (embodiments ) Tj 3.532537 0 Td 26.494024 Tz (, ) Tj 0.317928 0 Td 52.567508 Tz (methods ) Tj 2.384462 0 Td 50.044267 Tz (of ) Tj 0.671182 0 Td 44.156707 Tz (the ) Tj 0.953785 0 Td 46.119227 Tz (invention ) Tj 2.63174 0 Td 45.838867 Tz (include ) Tj 60.659341 0 0 60.659341 0 2166.535739 Tm 5.308333 0 Td 48.082729 Tz (be ) Tj 0.80779 0 Td 41.998792 Tz (present ) Tj 2.011232 0 Td 38.466184 Tz (in ) Tj 0.692391 0 Td 41.213768 Tz (a ) Tj 0.511051 0 Td 47.166868 Tz (second ) Tj 1.928804 0 Td 48.769626 Tz (Fhb1 ) Tj 1.483696 0 Td 36.17653 Tz (allele ) Tj 1.351812 0 Td 13.737923 Tz (, ) Tj 0.346196 0 Td 39.839976 Tz (as ) Tj 0.741848 0 Td 38.466184 Tz (in ) Tj 0.692391 0 Td 41.213768 Tz (a ) Tj 0.494565 0 Td 43.274457 Tz (case ) Tj 1.269384 0 Td 50.006039 Tz (where ) Tj 1.730978 0 Td 41.213768 Tz (the ) Tj 2.011232 0 Td 40.603194 Tz (culturing ) Tj 2.505797 0 Td 40.664251 Tz (plant ) Tj 1.516667 0 Td 38.924114 Tz (tissue ) Tj 1.730978 0 Td 27.475845 Tz (\( ) Tj 0.197826 0 Td 34.344807 Tz (e.g. ) Tj 0.906703 0 Td 13.737923 Tz (, ) Tj 0.428623 0 Td 39.15308 Tz (leaf ) Tj 0.906703 0 Td 24.728261 Tz (, ) Tj 0.461594 0 Td 44.877214 Tz (cotyledon ) Tj 2.456341 0 Td 13.737923 Tz (, ) Tj 0.428623 0 Td 41.213768 Tz (or ) Tj 0.774819 0 Td 45.793076 Tz (hypocotyl ) Tj 67.142857 0 0 67.142857 0 2120.894803 Tm 4.825532 0 Td 42.198582 Tz (second ) Tj 1.653191 0 Td 32.683215 Tz (allele ) Tj 1.310638 0 Td 28.546099 Tz (is ) Tj 0.491489 0 Td 43.191489 Tz (found ) Tj 1.4 0 Td 33.510638 Tz (to ) Tj 0.565957 0 Td 39.3026 Tz (confer ) Tj 1.534043 0 Td 37.234043 Tz (a ) Tj 0.342553 0 Td 39.716312 Tz (higher ) Tj 1.548936 0 Td 40.543735 Tz (degree ) Tj 1.608511 0 Td 40.957447 Tz (of ) Tj 0.551064 0 Td 36.489362 Tz (resistance ) Tj 2.248936 0 Td 9.929078 Tz (. ) Tj 0.446809 0 Td 33.510638 Tz (20 ) Tj 0.789362 0 Td 39.095745 Tz (explants ) Tj 1.861702 0 Td 24.822695 Tz (\) ) Tj 0.387234 0 Td 45.921986 Tz (on ) Tj 0.774468 0 Td 37.234043 Tz (a ) Tj 0.476596 0 Td 35.37234 Tz (suitable ) Tj 1.906383 0 Td 45.177305 Tz (media ) Tj 1.608511 0 Td 24.822695 Tz (\( ) Tj 0.16383 0 Td 31.648936 Tz (e.g. ) Tj 0.819149 0 Td 12.411348 Tz (, ) Tj 0.342553 0 Td 43.57762 Tz (Murashige ) Tj 2.591489 0 Td 44.680851 Tz (and ) Tj 1.02766 0 Td 46.170213 Tz (Skoog ) Tj 61.088435 0 0 61.088435 0 2080.808228 Tm 5.909465 0 Td 40.924276 Tz (In ) Tj 0.638419 0 Td 52.519488 Tz (some ) Tj 1.407795 0 Td 48.861105 Tz (embodiments ) Tj 3.257572 0 Td 24.554566 Tz (, ) Tj 0.294655 0 Td 41.833705 Tz (the ) Tj 0.900334 0 Td 42.43999 Tz (invention ) Tj 2.422717 0 Td 43.311526 Tz (provides ) Tj 2.226281 0 Td 49.109131 Tz (methods ) Tj 2.226281 0 Td 39.105419 Tz (for ) Tj 1.947996 0 Td 27.282851 Tz (\( ) Tj 0.180067 0 Td 70.935412 Tz (MS ) Tj 0.883964 0 Td 27.282851 Tz (\) ) Tj 0.229176 0 Td 13.641425 Tz (, ) Tj 0.376503 0 Td 46.380846 Tz (supplemented ) Tj 3.601336 0 Td 49.109131 Tz (media ) Tj 1.522383 0 Td 13.641425 Tz (, ) Tj 0.360134 0 Td 34.103563 Tz (etc. ) Tj 0.867595 0 Td 27.282851 Tz (\) ) Tj 0.425612 0 Td 45.357739 Tz (followed ) Tj 2.389978 0 Td 49.109131 Tz (by ) Tj 0.867595 0 Td 40.924276 Tz (introduction ) Tj 61.804511 0 0 61.804511 0 2041.69568 Tm 5.209976 0 Td 43.820965 Tz (reducing ) Tj 2.394647 0 Td 39.55123 Tz (the ) Tj 1.003163 0 Td 43.146796 Tz (production ) Tj 2.880049 0 Td 45.843471 Tz (of ) Tj 0.744282 0 Td 44.832218 Tz (pathogen ) Tj 2.281387 0 Td 26.966748 Tz (- ) Tj 0.14562 0 Td 41.528792 Tz (associated ) Tj 2.750608 0 Td 40.450122 Tz (toxins ) Tj 1.747445 0 Td 48.540146 Tz (by ) Tj 1.812165 0 Td 45.843471 Tz (of ) Tj 0.679562 0 Td 40.450122 Tz (the ) Tj 0.938443 0 Td 47.041993 Tz (exogenous ) Tj 2.766788 0 Td 40.835361 Tz (nucleic ) Tj 1.941606 0 Td 41.798459 Tz (acid ) Tj 1.197324 0 Td 37.753447 Tz (into ) Tj 1.116423 0 Td 40.450122 Tz (the ) Tj 0.922263 0 Td 38.202893 Tz (tissue ) Tj 1.569465 0 Td 43.146796 Tz (using ) Tj 1.537105 0 Td 38.090531 Tz (suitable ) Tj 59.365079 0 0 59.365079 0 2001.232037 Tm 5.440909 0 Td 42.673797 Tz (increasing ) Tj 2.947861 0 Td 42.112299 Tz (the ) Tj 1.145455 0 Td 42.914439 Tz (disease ) Tj 2.172995 0 Td 42.736185 Tz (tolerance ) Tj 2.695187 0 Td 47.727273 Tz (of ) Tj 0.875936 0 Td 42.112299 Tz (the ) Tj 1.145455 0 Td 41.550802 Tz (plant ) Tj 1.633957 0 Td 44.919786 Tz (using ) Tj 1.735027 0 Td 42.112299 Tz (the ) Tj 2.02139 0 Td 45.200535 Tz (techniques ) Tj 2.644652 0 Td 28.074866 Tz (. ) Tj 0.437968 0 Td 53.342246 Tz (The ) Tj 1.212834 0 Td 48.975045 Tz (exogenous ) Tj 2.897326 0 Td 42.513369 Tz (nucleic ) Tj 2.05508 0 Td 43.516043 Tz (acid ) Tj 1.280214 0 Td 47.727273 Tz (can ) Tj 1.078075 0 Td 49.131016 Tz (be ) Tj 0.842246 0 Td 44.639037 Tz (introduced ) Tj 57.744361 0 0 57.744361 0 1957.167546 Tm 5.576302 0 Td 51.540799 Tz (methods ) Tj 2.580339 0 Td 45.859857 Tz (described ) Tj 2.840104 0 Td 41.851128 Tz (herein ) Tj 1.645182 0 Td 20.203993 Tz (. ) Tj 0.519531 0 Td 47.623698 Tz (Toxins ) Tj 2.130078 0 Td 47.14265 Tz (addressed ) Tj 2.909375 0 Td 53.396267 Tz (by ) Tj 1.021745 0 Td 44.943576 Tz (various ) Tj 3.203776 0 Td 46.180556 Tz (using ) Tj 1.714453 0 Td 43.294271 Tz (a ) Tj 0.571484 0 Td 44.897762 Tz (construct ) Tj 2.389844 0 Td 23.090278 Tz (, ) Tj 0.45026 0 Td 46.180556 Tz (vector ) Tj 1.610547 0 Td 23.090278 Tz (, ) Tj 0.415625 0 Td 49.06684 Tz (plasmid ) Tj 2.355208 0 Td 44.737413 Tz (or ) Tj 0.83125 0 Td 44.448785 Tz (other ) Tj 1.645182 0 Td 41.129557 Tz (suitable ) Tj 2.337891 0 Td 53.396267 Tz (tech ) Tj 64.285714 0 0 64.285714 0 1913.192455 Tm 5.024444 0 Td 46.902357 Tz (embodiments ) Tj 3.36 0 Td 44.074074 Tz (of ) Tj 0.7 0 Td 38.888889 Tz (the ) Tj 0.948889 0 Td 40.617284 Tz (invention ) Tj 2.426667 0 Td 40.37037 Tz (include ) Tj 1.944444 0 Td 42.518519 Tz (fumonisins ) Tj 2.815556 0 Td 45.802469 Tz (and ) Tj 1.057778 0 Td 28.518519 Tz (tri- ) Tj 1.073333 0 Td 33.703704 Tz (25 ) Tj 0.808889 0 Td 42 Tz (nique ) Tj 1.291111 0 Td 25.925926 Tz (. ) Tj 0.482222 0 Td 42.777778 Tz (Expression ) Tj 2.893333 0 Td 44.074074 Tz (of ) Tj 0.793333 0 Td 38.888889 Tz (the ) Tj 1.026667 0 Td 40.185185 Tz (nucleotide ) Tj 2.768889 0 Td 43.75 Tz (sequence ) Tj 2.426667 0 Td 35.555556 Tz (results ) Tj 1.851111 0 Td 36.296296 Tz (in ) Tj 60.142857 0 0 60.142857 0 1874.186691 Tm 5.370546 0 Td 45.346577 Tz (chothecenes ) Tj 3.059382 0 Td 19.398258 Tz (. ) Tj 0.365796 0 Td 41.567696 Tz (In ) Tj 0.714964 0 Td 39.904988 Tz (particular ) Tj 2.344418 0 Td 27.711797 Tz (, ) Tj 0.39905 0 Td 41.567696 Tz (the ) Tj 0.997625 0 Td 43.415149 Tz (invention ) Tj 2.56057 0 Td 44.338876 Tz (provides ) Tj 2.377672 0 Td 49.485352 Tz (methods ) Tj 3.35867 0 Td 45.598503 Tz (transformed ) Tj 3.159145 0 Td 42.953286 Tz (or ) Tj 0.648456 0 Td 46.070863 Tz (modified ) Tj 2.361045 0 Td 38.796516 Tz (tissue ) Tj 1.463183 0 Td 11.084719 Tz (. ) Tj 0.266033 0 Td 45.031671 Tz (Reporter ) Tj 2.311164 0 Td 46.001584 Tz (genes ) Tj 1.562945 0 Td 48.033782 Tz (and ) Tj 0.980998 0 Td 19.398258 Tz (/ ) Tj 0.149644 0 Td 37.410926 Tz (or ) Tj 0.665083 0 Td 44.893112 Tz (selec ) Tj 57.642857 0 0 57.642857 0 1833.262117 Tm 5.60347 0 Td 41.44293 Tz (for ) Tj 0.954151 0 Td 42.581953 Tz (genetically ) Tj 3.018587 0 Td 49.795769 Tz (modifying ) Tj 2.89715 0 Td 42.406719 Tz (plants ) Tj 1.73482 0 Td 39.033457 Tz (to ) Tj 0.693928 0 Td 46.261875 Tz (render ) Tj 1.856258 0 Td 53.490293 Tz (them ) Tj 1.474597 0 Td 55.658819 Tz (more ) Tj 1.561338 0 Td 38.551563 Tz (resis- ) Tj 2.688971 0 Td 41.924824 Tz (tion ) Tj 1.214374 0 Td 52.622883 Tz (media ) Tj 1.804213 0 Td 49.153242 Tz (can ) Tj 1.092937 0 Td 49.153242 Tz (be ) Tj 0.815366 0 Td 49.153242 Tz (used ) Tj 1.387856 0 Td 39.033457 Tz (to ) Tj 0.745973 0 Td 39.515352 Tz (select ) Tj 1.665428 0 Td 41.44293 Tz (for ) Tj 0.954151 0 Td 51.080821 Tz (and ) Tj 1.127633 0 Td 42.406719 Tz (verify ) Tj 1.821561 0 Td 49.442379 Tz (transforma ) Tj 55.306122 0 0 55.306122 0 1792.952781 Tm 5.82214 0 Td 42.189422 Tz (tant ) Tj 1.319926 0 Td 40.682657 Tz (to ) Tj 0.795572 0 Td 54.620234 Tz (Fusarium ) Tj 2.965314 0 Td 43.863605 Tz (infection ) Tj 2.350554 0 Td 27.121771 Tz (, ) Tj 0.506273 0 Td 48.216482 Tz (thereby ) Tj 2.332472 0 Td 48.969865 Tz (reducing ) Tj 2.676015 0 Td 45.202952 Tz (the ) Tj 1.139114 0 Td 42.189422 Tz (level ) Tj 1.609225 0 Td 51.230012 Tz (of ) Tj 1.916605 0 Td 43.696187 Tz (tion ) Tj 1.102952 0 Td 12.054121 Tz (. ) Tj 0.325461 0 Td 57.257073 Tz (The ) Tj 1.247601 0 Td 49.586269 Tz (transformed ) Tj 3.471587 0 Td 42.189422 Tz (tissue ) Tj 1.753875 0 Td 52.234522 Tz (can ) Tj 1.139114 0 Td 48.216482 Tz (then ) Tj 1.356089 0 Td 52.736777 Tz (be ) Tj 0.849815 0 Td 51.983395 Tz (used ) Tj 1.446494 0 Td 40.682657 Tz (to ) Tj 0.723247 0 Td 47.01107 Tz (regenerate ) Tj 61.729323 0 0 61.729323 0 1749.614383 Tm 5.216322 0 Td 56.699147 Tz (De ) Tj 0.761389 0 Td 26.999594 Tz (- ) Tj 0.178197 0 Td 42.974354 Tz (oxynivalenol ) Tj 3.418149 0 Td 26.999594 Tz (\( ) Tj 0.178197 0 Td 71.998917 Tz (DON ) Tj 1.31218 0 Td 26.999594 Tz (\) ) Tj 0.469793 0 Td 48.599269 Tz (and ) Tj 1.150183 0 Td 41.039383 Tz (other ) Tj 1.490378 0 Td 40.499391 Tz (toxins ) Tj 1.765773 0 Td 41.309379 Tz (associated ) Tj 2.737759 0 Td 45.22432 Tz (with ) Tj 2.300365 0 Td 41.039383 Tz (transgenic ) Tj 2.64056 0 Td 49.139261 Tz (whole ) Tj 1.636175 0 Td 39.599405 Tz (plants ) Tj 1.587576 0 Td 45.449317 Tz (having ) Tj 1.814373 0 Td 42.299364 Tz (increased ) Tj 2.446163 0 Td 40.885099 Tz (disease ) Tj 1.879172 0 Td 39.689403 Tz (resistance ) Tj 2.446163 0 Td 10.799838 Tz (. ) Tj 61.428571 0 0 61.428571 0 1707.541616 Tm 5.225581 0 Td 46.124031 Tz (Fusarium ) Tj 2.393023 0 Td 18.992248 Tz (. ) Tj 0.293023 0 Td 40.697674 Tz (In ) Tj 0.618605 0 Td 41.602067 Tz (preferred ) Tj 2.376744 0 Td 49.82382 Tz (embodiments ) Tj 3.272093 0 Td 24.418605 Tz (, ) Tj 0.276744 0 Td 41.782946 Tz (these ) Tj 1.383721 0 Td 48.449612 Tz (methods ) Tj 2.213953 0 Td 43.023256 Tz (involve ) Tj 2.197674 0 Td 36.627907 Tz (30 ) Tj 0.862791 0 Td 43.953488 Tz (Transgenic ) Tj 2.930233 0 Td 39.793282 Tz (plants ) Tj 1.74186 0 Td 47.028424 Tz (can ) Tj 1.106977 0 Td 47.48062 Tz (be ) Tj 0.846512 0 Td 43.1642 Tz (regenerated ) Tj 3.109302 0 Td 43.410853 Tz (using ) Tj 1.595349 0 Td 41.860465 Tz (various ) Tj 2.1 0 Td 48.837209 Tz (tech ) Tj 58.421053 0 0 58.421053 0 1670.24486 Tm 5.511712 0 Td 42.274092 Tz (genetically ) Tj 2.995495 0 Td 49.132466 Tz (modifying ) Tj 2.875676 0 Td 42.792793 Tz (the ) Tj 1.00991 0 Td 41.651652 Tz (plant ) Tj 1.489189 0 Td 40.890891 Tz (for ) Tj 0.941441 0 Td 44.694695 Tz (increased ) Tj 2.618919 0 Td 43.607894 Tz (disease ) Tj 2.054054 0 Td 38.513514 Tz (resis- ) Tj 2.67027 0 Td 45.645646 Tz (niques ) Tj 1.848649 0 Td 48.815482 Tz (depending ) Tj 2.807207 0 Td 53.490991 Tz (upon ) Tj 1.437838 0 Td 43.743744 Tz (the ) Tj 0.958559 0 Td 42.222222 Tz (plant ) Tj 1.472072 0 Td 42.385242 Tz (species ) Tj 1.985586 0 Td 44.932432 Tz (involved ) Tj 2.208108 0 Td 22.822823 Tz (. ) Tj 0.359459 0 Td 42.792793 Tz (In ) Tj 0.684685 0 Td 50.4004 Tz (one ) Tj 1.095495 0 Td 44.219219 Tz (or ) Tj 59.126984 0 0 59.126984 0 1625.215561 Tm 5.445906 0 Td 43.973154 Tz (tance ) Tj 1.623624 0 Td 47.214765 Tz (with ) Tj 1.403758 0 Td 42.684564 Tz (respect ) Tj 2.080268 0 Td 38.053691 Tz (to ) Tj 0.794899 0 Td 42.281879 Tz (a ) Tj 0.558121 0 Td 43.087248 Tz (disease ) Tj 2.097181 0 Td 39.463087 Tz (that ) Tj 1.251544 0 Td 40.671141 Tz (creates ) Tj 2.02953 0 Td 42.281879 Tz (toxins ) Tj 1.572886 0 Td 14.09396 Tz (, ) Tj 0.405906 0 Td 45.66443 Tz (using ) Tj 2.655302 0 Td 53.557047 Tz (more ) Tj 1.505235 0 Td 50.994509 Tz (embodiments ) Tj 3.348725 0 Td 25.369128 Tz (, ) Tj 0.372081 0 Td 43.926174 Tz (regeneration ) Tj 3.365638 0 Td 46.666667 Tz (comprises ) Tj 2.739866 0 Td 45.805369 Tz (inducing ) Tj 2.401611 0 Td 39.932886 Tz (callus ) Tj 57.321429 0 0 57.321429 0 1583.239211 Tm 5.617445 0 Td 51.92108 Tz (methods ) Tj 2.442368 0 Td 45.875159 Tz (described ) Tj 2.686604 0 Td 45.552094 Tz (herein ) Tj 1.674766 0 Td 11.630322 Tz (. ) Tj 0.331464 0 Td 54.274836 Tz (The ) Tj 1.221184 0 Td 45.22903 Tz (invention ) Tj 2.669159 0 Td 41.433022 Tz (also ) Tj 1.256075 0 Td 51.014821 Tz (encompasses ) Tj 51.904762 0 0 51.904762 0 1586.027451 Tm 24.988073 0 Td 52.446483 Tz (formation ) Tj 3.082569 0 Td 56.995413 Tz (from ) Tj 1.599083 0 Td 49.235474 Tz (the ) Tj 1.117431 0 Td 52.835696 Tz (transformed ) Tj 4.566055 0 Td 43.883792 Tz (sue ) Tj 0.82844 0 Td 16.055046 Tz (, ) Tj 0.404587 0 Td 56.727829 Tz (and ) Tj 1.252294 0 Td 50.038226 Tz (regeneration ) Tj 3.853211 0 Td 54.587156 Tz (of ) Tj 58.77551 0 0 58.77551 0 1543.469825 Tm 5.478472 0 Td 41.589506 Tz (plants ) Tj 1.735417 0 Td 45.37037 Tz (generated ) Tj 2.654167 0 Td 51.041667 Tz (by ) Tj 0.850694 0 Td 43.101852 Tz (these ) Tj 1.497222 0 Td 50.636574 Tz (methods ) Tj 2.126736 0 Td 25.520833 Tz (, ) Tj 0.391319 0 Td 44.110082 Tz (including ) Tj 2.586111 0 Td 41.589506 Tz (plants ) Tj 1.701389 0 Td 48.206019 Tz (having ) Tj 3.0625 0 Td 43.00733 Tz (shoots ) Tj 1.565278 0 Td 25.520833 Tz (, ) Tj 0.459375 0 Td 46.788194 Tz (followed ) Tj 2.501042 0 Td 52.459491 Tz (by ) Tj 0.901736 0 Td 43.344907 Tz (rooting ) Tj 2.109722 0 Td 48.206019 Tz (of ) Tj 0.765625 0 Td 42.534722 Tz (the ) Tj 1.071875 0 Td 43.479938 Tz (shoots ) Tj 1.871528 0 Td 39.699074 Tz (in ) Tj 0.765625 0 Td 35.445602 Tz (soil ) Tj 1.156944 0 Td 43.952546 Tz (or ) Tj 0.782639 0 Td 43.668981 Tz (other ) Tj 62.857143 0 0 62.857143 0 1498.502857 Tm 5.138636 0 Td 39.772727 Tz (a ) Tj 0.397727 0 Td 44.69697 Tz (reduced ) Tj 2.052273 0 Td 37.310606 Tz (susceptibility ) Tj 3.277273 0 Td 37.121212 Tz (to ) Tj 0.604545 0 Td 40.833333 Tz (toxin ) Tj 1.368182 0 Td 42.424242 Tz (buildup ) Tj 1.956818 0 Td 37.121212 Tz (relative ) Tj 1.925 0 Td 35.795455 Tz (to ) Tj 0.620455 0 Td 39.772727 Tz (a ) Tj 0.397727 0 Td 39.393939 Tz (control ) Tj 2.052273 0 Td 34.469697 Tz (35 ) Tj 0.843182 0 Td 40.736915 Tz (appropriate ) Tj 2.895455 0 Td 40.530303 Tz (rooting ) Tj 1.909091 0 Td 48.257576 Tz (media ) Tj 1.654545 0 Td 37.121212 Tz (to ) Tj 0.684091 0 Td 41.429924 Tz (generate ) Tj 2.195455 0 Td 39.772727 Tz (the ) Tj 0.922727 0 Td 48.257576 Tz (whole ) Tj 1.654545 0 Td 41.363636 Tz (plant ) Tj 1.177273 0 Td 26.515152 Tz (. ) Tj 63.533835 0 0 63.533835 0 1457.030401 Tm 5.068166 0 Td 43.546351 Tz (plant ) Tj 1.148994 0 Td 26.232742 Tz (. ) Tj 0.45645 0 Td 39.349112 Tz (In ) Tj 0.739763 0 Td 37.600263 Tz (particularly ) Tj 2.974793 0 Td 39.932062 Tz (preferred ) Tj 2.439645 0 Td 47.218935 Tz (embodiments ) Tj 3.11645 0 Td 23.609467 Tz (, ) Tj 0.44071 0 Td 40.223537 Tz (the ) Tj 0.991598 0 Td 38.824458 Tz (plant ) Tj 1.448047 0 Td 30.167653 Tz (is ) Tj 2.172071 0 Td 49.842209 Tz (The ) Tj 1.086036 0 Td 37.891738 Tz (resulting ) Tj 2.21929 0 Td 40.136095 Tz (transgenic ) Tj 2.597041 0 Td 38.474688 Tz (plants ) Tj 1.605444 0 Td 44.595661 Tz (can ) Tj 0.960118 0 Td 45.907298 Tz (be ) Tj 0.755503 0 Td 41.597633 Tz (crossed ) Tj 1.920237 0 Td 35.414201 Tz (to ) Tj 0.629586 0 Td 41.972387 Tz (prepare ) Tj 61.142857 0 0 61.142857 0 1416.513286 Tm 5.266355 0 Td 42.250779 Tz (barley ) Tj 1.733645 0 Td 40.88785 Tz (or ) Tj 0.670561 0 Td 48.520249 Tz (wheat ) Tj 1.504673 0 Td 10.903427 Tz (. ) Tj 0.294393 0 Td 43.613707 Tz (This ) Tj 1.275701 0 Td 41.796469 Tz (aspect ) Tj 1.700935 0 Td 46.339564 Tz (of ) Tj 0.686916 0 Td 40.88785 Tz (the ) Tj 0.932243 0 Td 42.705088 Tz (invention ) Tj 2.502336 0 Td 29.984424 Tz (is ) Tj 0.57243 0 Td 39.070613 Tz (particularly ) Tj 4.056075 0 Td 46.728972 Tz (progeny ) Tj 1.962617 0 Td 19.080997 Tz (, ) Tj 0.507009 0 Td 49.065421 Tz (and ) Tj 1.21028 0 Td 41.705607 Tz (preferably ) Tj 2.86215 0 Td 51.791277 Tz (homozygous ) Tj 3.46729 0 Td 47.507788 Tz (progeny ) Tj 2.371495 0 Td 40.88785 Tz (or ) Tj 0.866822 0 Td 41.978193 Tz (seeds ) Tj 1.341121 0 Td 10.903427 Tz (. ) Tj 60 0 0 60 0 1373.984839 Tm 5.366667 0 Td 41.666667 Tz (useful ) Tj 1.7 0 Td 39.814815 Tz (for ) Tj 0.866667 0 Td 45.138889 Tz (reducing ) Tj 2.35 0 Td 74.074074 Tz (DON ) Tj 1.5 0 Td 43.253968 Tz (content ) Tj 2 0 Td 38.888889 Tz (in ) Tj 0.616667 0 Td 43.055556 Tz (barley ) Tj 1.716667 0 Td 44.097222 Tz (products ) Tj 2.3 0 Td 47.916667 Tz (used ) Tj 1.3 0 Td 51.388889 Tz (by ) Tj 1.9 0 Td 50 Tz (Thus ) Tj 1.216667 0 Td 25 Tz (, ) Tj 0.383333 0 Td 41.666667 Tz (disease ) Tj 1.9 0 Td 19.444444 Tz (- ) Tj 0.166667 0 Td 37.037037 Tz (resistant ) Tj 2.216667 0 Td 40.740741 Tz (plants ) Tj 1.716667 0 Td 27.777778 Tz (\( ) Tj 0.2 0 Td 34.722222 Tz (e.g. ) Tj 0.916667 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 60.185185 Tz (FHB ) Tj 1.3 0 Td 19.444444 Tz (- ) Tj 0.2 0 Td 36.728395 Tz (resistant ) Tj 2.183333 0 Td 49.444444 Tz (wheat ) Tj 1.716667 0 Td 43.055556 Tz (or ) Tj 59.548872 0 0 59.548872 0 1336.005894 Tm 5.39053 0 Td 41.982323 Tz (the ) Tj 1.108333 0 Td 43.381734 Tz (barley ) Tj 1.931187 0 Td 45.180976 Tz (malting ) Tj 2.283838 0 Td 39.183502 Tz (in ) Tj 0.822854 0 Td 48.37963 Tz (brewing ) Tj 2.418182 0 Td 40.30303 Tz (industries ) Tj 2.401389 0 Td 22.390572 Tz (. ) Tj 0.520581 0 Td 45.98064 Tz (Nucleic ) Tj 2.317424 0 Td 41.982323 Tz (acids ) Tj 2.569318 0 Td 42.448793 Tz (barley ) Tj 1.578535 0 Td 27.988215 Tz (\) ) Tj 0.419823 0 Td 48.512907 Tz (can ) Tj 1.09154 0 Td 39.883207 Tz (also ) Tj 1.209091 0 Td 47.579966 Tz (be ) Tj 0.806061 0 Td 48.629524 Tz (produced ) Tj 2.552525 0 Td 39.743266 Tz (indirectly ) Tj 2.602904 0 Td 51.778199 Tz (by ) Tj 0.839646 0 Td 45.48085 Tz (breeding ) Tj 2.418182 0 Td 43.381734 Tz (parent ) Tj 64.285714 0 0 64.285714 0 1288.596043 Tm 5.008889 0 Td 43.101852 Tz (provided ) Tj 2.255556 0 Td 47.962963 Tz (by ) Tj 0.777778 0 Td 38.888889 Tz (the ) Tj 0.917778 0 Td 40.617284 Tz (invention ) Tj 2.395556 0 Td 44.074074 Tz (can ) Tj 0.98 0 Td 45.37037 Tz (be ) Tj 0.762222 0 Td 41.222222 Tz (introduced ) Tj 2.675556 0 Td 36.296296 Tz (in ) Tj 0.622222 0 Td 40.185185 Tz (barley ) Tj 1.664444 0 Td 37.592593 Tz (as ) Tj 0.684444 0 Td 38.888889 Tz (a ) Tj 0.591111 0 Td 36.296296 Tz (40 ) Tj 0.824444 0 Td 38.024691 Tz (plants ) Tj 1.648889 0 Td 43.641975 Tz (having ) Tj 1.851111 0 Td 40.329218 Tz (increased ) Tj 2.457778 0 Td 38.148148 Tz (disease ) Tj 1.757778 0 Td 18.148148 Tz (- ) Tj 0.171111 0 Td 36.814815 Tz (resistance ) Tj 2.473333 0 Td 43.425926 Tz (with ) Tj 1.306667 0 Td 39.407407 Tz (other ) Tj 1.54 0 Td 42.345679 Tz (dis ) Tj 59.251701 0 0 59.251701 0 1249.612428 Tm 5.434443 0 Td 52.881745 Tz (means ) Tj 1.822732 0 Td 40.317643 Tz (for ) Tj 0.911366 0 Td 45.708955 Tz (reducing ) Tj 2.413433 0 Td 75.009568 Tz (DON ) Tj 1.569575 0 Td 43.398393 Tz (content ) Tj 2.042135 0 Td 40.786452 Tz (in ) Tj 0.675086 0 Td 43.130501 Tz (barley ) Tj 1.772101 0 Td 45.357348 Tz (products ) Tj 2.126521 0 Td 28.128588 Tz (, ) Tj 0.405052 0 Td 39.848833 Tz (either ) Tj 2.717222 0 Td 44.302526 Tz (ease ) Tj 1.181401 0 Td 19.690011 Tz (- ) Tj 0.168772 0 Td 37.504784 Tz (resistant ) Tj 2.329047 0 Td 42.192882 Tz (plants ) Tj 1.468312 0 Td 28.128588 Tz (, ) Tj 0.506315 0 Td 43.599311 Tz (or ) Tj 0.82698 0 Td 49.225029 Tz (even ) Tj 1.468312 0 Td 47.115385 Tz (with ) Tj 1.434558 0 Td 42.755454 Tz (other ) Tj 1.586452 0 Td 39.380023 Tz (cultivars ) Tj 2.447187 0 Td 47.34979 Tz (having ) Tj 62.857143 0 0 62.857143 0 1212.320144 Tm 5.122727 0 Td 39.393939 Tz (transgenically ) Tj 3.531818 0 Td 42.424242 Tz (or ) Tj 0.7 0 Td 47.727273 Tz (by ) Tj 0.795455 0 Td 43.087121 Tz (breeding ) Tj 2.290909 0 Td 37.121212 Tz (strategies ) Tj 2.195455 0 Td 26.515152 Tz (. ) Tj 62.857143 0 0 62.857143 0 1205.30092 Tm 20.634091 0 Td 39.242424 Tz (additional ) Tj 2.704545 0 Td 40.530303 Tz (desired ) Tj 2.036364 0 Td 37.29798 Tz (characteristics ) Tj 3.738636 0 Td 26.515152 Tz (\( ) Tj 0.175 0 Td 33.806818 Tz (e.g. ) Tj 0.875 0 Td 13.257576 Tz (, ) Tj 0.445455 0 Td 39.109848 Tz (pest ) Tj 1.288636 0 Td 41.098485 Tz (or ) Tj 0.795455 0 Td 40.951178 Tz (herbicide ) Tj 60.676692 0 0 60.676692 0 1165.166348 Tm 5.949566 0 Td 41.201983 Tz (In ) Tj 0.642751 0 Td 52.875878 Tz (some ) Tj 1.417348 0 Td 49.19267 Tz (embodiments ) Tj 3.279678 0 Td 24.72119 Tz (, ) Tj 0.296654 0 Td 42.117582 Tz (the ) Tj 0.906444 0 Td 42.727982 Tz (invention ) Tj 2.439157 0 Td 43.605432 Tz (provides ) Tj 2.241388 0 Td 49.442379 Tz (methods ) Tj 2.241388 0 Td 39.370783 Tz (for ) Tj 1.944734 0 Td 39.279223 Tz (resistance ) Tj 2.406196 0 Td 24.72119 Tz (, ) Tj 0.444981 0 Td 45.047501 Tz (geographic ) Tj 2.999504 0 Td 41.201983 Tz (adaptation ) Tj 2.505081 0 Td 27.467988 Tz (, ) Tj 0.494424 0 Td 37.905824 Tz (stalk ) Tj 1.417348 0 Td 38.111834 Tz (strength ) Tj 1.944734 0 Td 27.467988 Tz (, ) Tj 0.428501 0 Td 48.06898 Tz (he ) Tj 0.939405 0 Td 40.103263 Tz (toler ) Tj 59.52381 0 0 59.52381 0 1127.570323 Tm 5.4432 0 Td 41.236364 Tz (identifying ) Tj 2.9568 0 Td 36 Tz (allelic ) Tj 1.7808 0 Td 41.3 Tz (variants ) Tj 2.2512 0 Td 44.8 Tz (with ) Tj 1.344 0 Td 49.7 Tz (improved ) Tj 2.6544 0 Td 39.415385 Tz (functionality ) Tj 3.1416 0 Td 28 Tz (. ) Tj 0.42 0 Td 42 Tz (In ) Tj 1.7808 0 Td 46.9 Tz (ance ) Tj 1.1424 0 Td 16.8 Tz (, ) Tj 0.3864 0 Td 35 Tz (etc. ) Tj 0.8904 0 Td 28 Tz (\) ) Tj 0.252 0 Td 11.2 Tz (. ) Tj 0.336 0 Td 53.2 Tz (The ) Tj 1.1928 0 Td 40.444444 Tz (resulting ) Tj 2.436 0 Td 48.4 Tz (progeny ) Tj 2.3016 0 Td 47.6 Tz (can ) Tj 1.0752 0 Td 44.8 Tz (then ) Tj 1.3272 0 Td 47.6 Tz (be ) Tj 0.84 0 Td 45.5 Tz (screened ) Tj 2.4024 0 Td 37.8 Tz (to ) Tj 58.571429 0 0 58.571429 0 1084.721066 Tm 5.514634 0 Td 43.821138 Tz (other ) Tj 1.673171 0 Td 51.736881 Tz (embodiments ) Tj 3.414634 0 Td 25.609756 Tz (, ) Tj 0.512195 0 Td 42.682927 Tz (the ) Tj 1.160976 0 Td 44.263776 Tz (invention ) Tj 2.74878 0 Td 45.172764 Tz (provides ) Tj 2.543902 0 Td 50.813008 Tz (methods ) Tj 2.543902 0 Td 40.785908 Tz (for ) Tj 1.109756 0 Td 38.414634 Tz (45 ) Tj 0.921951 0 Td 40.904472 Tz (identify ) Tj 2.185366 0 Td 49.593496 Tz (progeny ) Tj 2.304878 0 Td 47.899729 Tz (having ) Tj 1.963415 0 Td 44.579946 Tz (increased ) Tj 2.629268 0 Td 43.089431 Tz (disease ) Tj 1.860976 0 Td 25.609756 Tz (- ) Tj 0.170732 0 Td 41.829268 Tz (resistance ) Tj 2.578049 0 Td 11.382114 Tz (. ) Tj 59.214286 0 0 59.214286 0 1042.582908 Tm 5.454765 0 Td 41.70779 Tz (identifying ) Tj 2.904704 0 Td 42.219542 Tz (genetic ) Tj 1.942099 0 Td 47.848814 Tz (markers ) Tj 2.178528 0 Td 40.343118 Tz (for ) Tj 0.861279 0 Td 43.023723 Tz (disease ) Tj 1.942099 0 Td 41.375151 Tz (resistance ) Tj 2.448733 0 Td 25.331725 Tz (, ) Tj 0.320869 0 Td 51.789304 Tz (which ) Tj 1.688782 0 Td 48.787026 Tz (can ) Tj 2.78649 0 Td 41.750436 Tz (Plants ) Tj 1.756333 0 Td 46.441496 Tz (of ) Tj 0.709288 0 Td 42.219542 Tz (the ) Tj 0.962606 0 Td 43.425814 Tz (present ) Tj 2.043426 0 Td 44.095966 Tz (invention ) Tj 2.600724 0 Td 43.425814 Tz (include ) Tj 2.060314 0 Td 42.219542 Tz (a ) Tj 0.455971 0 Td 41.656614 Tz (plant ) Tj 1.46924 0 Td 38.701246 Tz (that ) Tj 1.148372 0 Td 45.034178 Tz (has ) Tj 1.047045 0 Td 42.219542 Tz (a ) Tj 58.198758 0 0 58.198758 0 1001.12998 Tm 5.532764 0 Td 50.115617 Tz (be ) Tj 0.876307 0 Td 42.956243 Tz (useful ) Tj 1.872892 0 Td 40.092494 Tz (in ) Tj 0.75603 0 Td 46.392743 Tz (procedures ) Tj 3.127215 0 Td 47.967805 Tz (such ) Tj 1.426147 0 Td 41.524369 Tz (as ) Tj 0.790395 0 Td 49.638326 Tz (marker ) Tj 1.958805 0 Td 20.046247 Tz (- ) Tj 0.154642 0 Td 40.092494 Tz (assisted ) Tj 2.216542 0 Td 42.00166 Tz (selection ) Tj 3.556777 0 Td 42.097118 Tz (resistance ) Tj 2.714835 0 Td 40.665244 Tz (level ) Tj 1.426147 0 Td 48.683742 Tz (of ) Tj 0.704482 0 Td 50.831555 Tz (from ) Tj 1.460512 0 Td 28.637496 Tz (1 ) Tj 0.429562 0 Td 38.660619 Tz (to ) Tj 0.704482 0 Td 40.092494 Tz (5 ) Tj 0.309285 0 Td 14.318748 Tz (, ) Tj 0.378015 0 Td 28.637496 Tz (1 ) Tj 0.41238 0 Td 47.538243 Tz (being ) Tj 1.615155 0 Td 47.251868 Tz (completely ) Tj 3.02412 0 Td 56.7977 Tz (immune ) Tj 2.0619 0 Td 25.773746 Tz (, ) Tj 63.043478 0 0 63.043478 0 956.271805 Tm 5.13931 0 Td 34.367816 Tz (\( ) Tj 0.142759 0 Td 70.498084 Tz (MAS ) Tj 1.364138 0 Td 26.436782 Tz (\) ) Tj 0.126897 0 Td 26.436782 Tz (. ) Tj 0.491724 0 Td 39.655172 Tz (In ) Tj 0.808966 0 Td 50.890805 Tz (some ) Tj 1.538621 0 Td 48.30721 Tz (embodiments ) Tj 3.172414 0 Td 23.793103 Tz (, ) Tj 0.491724 0 Td 39.655172 Tz (a ) Tj 0.571034 0 Td 39.655172 Tz (genetic ) Tj 1.998621 0 Td 46.704981 Tz (marker ) Tj 1.998621 0 Td 44.942529 Tz (of ) Tj 0.793103 0 Td 39.655172 Tz (the ) Tj 1.935172 0 Td 42.298851 Tz (2 ) Tj 0.571034 0 Td 43.356322 Tz (being ) Tj 1.602069 0 Td 36.717752 Tz (resistant ) Tj 2.284138 0 Td 35.689655 Tz (to ) Tj 0.777241 0 Td 37.824934 Tz (substantially ) Tj 3.267586 0 Td 37.011494 Tz (resistant ) Tj 1.951034 0 Td 23.793103 Tz (, ) Tj 0.475862 0 Td 39.655172 Tz (3 ) Tj 0.571034 0 Td 43.356322 Tz (being ) Tj 1.570345 0 Td 66.97318 Tz (mid ) Tj 62.142857 0 0 62.142857 0 917.724293 Tm 5.197701 0 Td 42.01788 Tz (invention ) Tj 2.510345 0 Td 45.59387 Tz (can ) Tj 1.045977 0 Td 45.59387 Tz (be ) Tj 0.788506 0 Td 40.229885 Tz (useful ) Tj 1.721839 0 Td 38.44189 Tz (for ) Tj 0.917241 0 Td 39.74225 Tz (identifying ) Tj 2.864368 0 Td 40.229885 Tz (the ) Tj 0.965517 0 Td 43.582375 Tz (presence ) Tj 2.349425 0 Td 44.252874 Tz (of ) Tj 0.724138 0 Td 46.934866 Tz (an ) Tj 1.770115 0 Td 36.951894 Tz (resistant ) Tj 2.22069 0 Td 34.8659 Tz (to ) Tj 0.643678 0 Td 36.951894 Tz (partially ) Tj 2.188506 0 Td 37.845892 Tz (resistant ) Tj 2.027586 0 Td 24.137931 Tz (, ) Tj 0.321839 0 Td 48.275862 Tz (4 ) Tj 0.514943 0 Td 43.984674 Tz (being ) Tj 1.512644 0 Td 44.699872 Tz (mid ) Tj 0.981609 0 Td 26.819923 Tz (- ) Tj 0.225287 0 Td 38.279345 Tz (susceptible ) Tj 2.574713 0 Td 26.819923 Tz (, ) Tj 0.370115 0 Td 48.275862 Tz (and ) Tj 61.428571 0 0 61.428571 0 876.681614 Tm 5.25814 0 Td 48.158915 Tz (Fhbl ) Tj 1.497674 0 Td 48.837209 Tz (gene ) Tj 1.139535 0 Td 18.992248 Tz (, ) Tj 0.406977 0 Td 42.054264 Tz (or ) Tj 0.732558 0 Td 51.550388 Tz (more ) Tj 1.513953 0 Td 41.300603 Tz (generally ) Tj 2.506977 0 Td 40.697674 Tz (a ) Tj 0.504651 0 Td 41.085271 Tz (nucleic ) Tj 2.018605 0 Td 41.375969 Tz (acid ) Tj 1.253488 0 Td 45.784884 Tz (encoding ) Tj 2.474419 0 Td 47.48062 Tz (an ) Tj 0.944186 0 Td 36.627907 Tz (50 ) Tj 0.87907 0 Td 37.984496 Tz (5 ) Tj 0.455814 0 Td 44.496124 Tz (being ) Tj 1.562791 0 Td 40.451022 Tz (susceptible ) Tj 2.702326 0 Td 13.565891 Tz (, ) Tj 0.309302 0 Td 54.94186 Tz (when ) Tj 1.513953 0 Td 44.573643 Tz (assayed ) Tj 2.067442 0 Td 38.888889 Tz (for ) Tj 0.87907 0 Td 39.883721 Tz (resistance ) Tj 2.604651 0 Td 40.697674 Tz (or ) Tj 0.732558 0 Td 48.385013 Tz (suscep ) Tj 58.198758 0 0 58.198758 0 834.189865 Tm 5.549947 0 Td 61.570615 Tz (FHB1 ) Tj 1.99317 0 Td 43.36535 Tz (protein ) Tj 1.85571 0 Td 14.318748 Tz (, ) Tj 0.567022 0 Td 48.683742 Tz (an ) Tj 1.03095 0 Td 56.559054 Tz (Fhb1 ) Tj 1.357417 0 Td 20.046247 Tz (/ ) Tj 0.085912 0 Td 63.718428 Tz (FHB1 ) Tj 2.044717 0 Td 43.36535 Tz (variant ) Tj 1.78698 0 Td 25.773746 Tz (, ) Tj 0.601387 0 Td 50.115617 Tz (an ) Tj 1.03095 0 Td 54.411242 Tz (Fhb1 ) Tj 1.357417 0 Td 20.046247 Tz (/ ) Tj 0.189007 0 Td 60.138741 Tz (FHB1 ) Tj 2.800747 0 Td 35.438901 Tz (tibility ) Tj 1.975987 0 Td 37.228744 Tz (to ) Tj 0.738847 0 Td 65.86624 Tz (FHB ) Tj 1.460512 0 Td 52.979367 Tz (by ) Tj 0.910672 0 Td 49.638326 Tz (any ) Tj 1.134045 0 Td 53.93395 Tz (method ) Tj 2.19936 0 Td 50.473586 Tz (amenable ) Tj 2.68047 0 Td 38.660619 Tz (to ) Tj 0.738847 0 Td 42.956243 Tz (the ) Tj 1.013767 0 Td 47.09277 Tz (numerical ) Tj 56.785714 0 0 56.785714 0 794.694023 Tm 5.67044 0 Td 55.345912 Tz (homolog ) Tj 2.377358 0 Td 14.675052 Tz (, ) Tj 0.299371 0 Td 44.025157 Tz (or ) Tj 0.686792 0 Td 51.362683 Tz (an ) Tj 0.757233 0 Td 37.316562 Tz (allelic ) Tj 1.743396 0 Td 43.60587 Tz (variant ) Tj 1.972327 0 Td 49.40601 Tz (having ) Tj 1.954717 0 Td 63.102725 Tz (FHB1 ) Tj 1.761006 0 Td 39.989518 Tz (activity ) Tj 1.866667 0 Td 29.350105 Tz (. ) Tj 0.369811 0 Td 45.492662 Tz (In ) Tj 0.686792 0 Td 45.199161 Tz (other ) Tj 2.71195 0 Td 42.264151 Tz (scale ) Tj 1.514465 0 Td 46.634055 Tz (described ) Tj 2.72956 0 Td 44.025157 Tz (herein ) Tj 1.655346 0 Td 20.545073 Tz (. ) Tj 58.428571 0 0 58.428571 0 751.776559 Tm 5.528117 0 Td 51.863377 Tz (embodiments ) Tj 3.405868 0 Td 25.672372 Tz (, ) Tj 0.530562 0 Td 42.787286 Tz (a ) Tj 0.599022 0 Td 43.194784 Tz (genetic ) Tj 2.156479 0 Td 50.869329 Tz (marker ) Tj 2.156479 0 Td 48.492258 Tz (of ) Tj 0.838631 0 Td 42.787286 Tz (the ) Tj 1.129584 0 Td 44.688943 Tz (invention ) Tj 2.738386 0 Td 48.492258 Tz (can ) Tj 1.198044 0 Td 49.9185 Tz (be ) Tj 2.533007 0 Td 44.213529 Tz (In ) Tj 0.821516 0 Td 42.787286 Tz (a ) Tj 0.547677 0 Td 43.738115 Tz (preferred ) Tj 2.652812 0 Td 43.738115 Tz (aspect ) Tj 1.608802 0 Td 14.262429 Tz (, ) Tj 0.410758 0 Td 42.787286 Tz (the ) Tj 1.07824 0 Td 43.602282 Tz (present ) Tj 2.139364 0 Td 44.688943 Tz (invention ) Tj 2.687042 0 Td 45.283211 Tz (provides ) Tj 2.515892 0 Td 42.787286 Tz (a ) Tj 60 0 0 60 0 710.514054 Tm 5.366667 0 Td 41.666667 Tz (useful ) Tj 1.7 0 Td 39.814815 Tz (for ) Tj 0.883333 0 Td 40.909091 Tz (identifying ) Tj 2.883333 0 Td 41.666667 Tz (the ) Tj 0.916667 0 Td 45.138889 Tz (presence ) Tj 2.35 0 Td 47.222222 Tz (of ) Tj 0.683333 0 Td 47.222222 Tz (an ) Tj 0.733333 0 Td 35.31746 Tz (allelic ) Tj 1.666667 0 Td 41.269841 Tz (variant ) Tj 1.9 0 Td 47.222222 Tz (of ) Tj 0.683333 0 Td 48.611111 Tz (an ) Tj 1.833333 0 Td 41.111111 Tz (plant ) Tj 1.383333 0 Td 37.5 Tz (to ) Tj 0.616667 0 Td 48.611111 Tz (be ) Tj 0.75 0 Td 45.634921 Tz (assayed ) Tj 2.066667 0 Td 39.814815 Tz (for ) Tj 0.85 0 Td 40.833333 Tz (resistance ) Tj 2.616667 0 Td 41.666667 Tz (or ) Tj 0.666667 0 Td 39.087302 Tz (susceptibility ) Tj 3.433333 0 Td 37.5 Tz (to ) Tj 0.633333 0 Td 64.814815 Tz (FHB ) Tj 1.333333 0 Td 50 Tz (by ) Tj 67.142857 0 0 67.142857 0 664.11486 Tm 4.810638 0 Td 44.060284 Tz (Fhbl ) Tj 1.385106 0 Td 42.819149 Tz (gene ) Tj 1.280851 0 Td 38.475177 Tz (or ) Tj 0.685106 0 Td 46.808511 Tz (homolog ) Tj 2.010638 0 Td 12.411348 Tz (, ) Tj 0.342553 0 Td 37.978723 Tz (preferably ) Tj 2.546809 0 Td 42.198582 Tz (an ) Tj 0.759574 0 Td 31.560284 Tz (allelic ) Tj 1.578723 0 Td 36.879433 Tz (variant ) Tj 1.787234 0 Td 41.578014 Tz (with ) Tj 1.340426 0 Td 32.269504 Tz (55 ) Tj 0.789362 0 Td 43.026005 Tz (any ) Tj 0.997872 0 Td 46.749409 Tz (method ) Tj 1.891489 0 Td 33.510638 Tz (to ) Tj 0.655319 0 Td 40.819543 Tz (determine ) Tj 2.42766 0 Td 42.907801 Tz (whether ) Tj 2.010638 0 Td 37.234043 Tz (a ) Tj 0.446809 0 Td 36.737589 Tz (plant ) Tj 1.325532 0 Td 39.716312 Tz (has ) Tj 0.968085 0 Td 37.234043 Tz (a ) Tj 0.446809 0 Td 36.489362 Tz (resistance ) Tj 62.727273 0 0 62.727273 0 625.080135 Tm 5.149275 0 Td 39.4755 Tz (greater ) Tj 1.928986 0 Td 40.614217 Tz (disease ) Tj 1.992754 0 Td 39.057971 Tz (resistance ) Tj 2.630435 0 Td 38.833148 Tz (functionality ) Tj 3.315942 0 Td 43.176329 Tz (than ) Tj 1.323188 0 Td 46.05475 Tz (one ) Tj 1.131884 0 Td 41.183575 Tz (or ) Tj 0.749275 0 Td 51.147343 Tz (more ) Tj 2.455072 0 Td 37.198068 Tz (level ) Tj 1.371014 0 Td 43.84058 Tz (of ) Tj 0.701449 0 Td 47.826087 Tz (from ) Tj 1.418841 0 Td 26.570048 Tz (1 ) Tj 0.446377 0 Td 35.869565 Tz (to ) Tj 0.701449 0 Td 37.198068 Tz (5 ) Tj 0.286957 0 Td 13.285024 Tz (, ) Tj 0.398551 0 Td 26.570048 Tz (1 ) Tj 0.446377 0 Td 43.574879 Tz (being ) Tj 1.546377 0 Td 43.574879 Tz (completely ) Tj 2.853623 0 Td 52.254428 Tz (immune ) Tj 1.913043 0 Td 23.913043 Tz (, ) Tj 0.398551 0 Td 42.512077 Tz (2 ) Tj 0.494203 0 Td 43.574879 Tz (being ) Tj 60.680272 0 0 60.680272 0 583.394175 Tm 5.322982 0 Td 42.298206 Tz (other ) Tj 1.532623 0 Td 40.856222 Tz (national ) Tj 2.274215 0 Td 43.335825 Tz (occurring ) Tj 2.636771 0 Td 36.491031 Tz (alleles ) Tj 1.615022 0 Td 10.986547 Tz (. ) Tj 0.395516 0 Td 41.199552 Tz (In ) Tj 0.774552 0 Td 42.298206 Tz (other ) Tj 1.549103 0 Td 50.188545 Tz (embodiments ) Tj 3.295964 0 Td 24.719731 Tz (, ) Tj 0.461435 0 Td 41.199552 Tz (a ) Tj 1.499664 0 Td 37.842551 Tz (resistant ) Tj 2.274215 0 Td 38.452915 Tz (to ) Tj 0.741592 0 Td 39.298034 Tz (substantially ) Tj 3.312444 0 Td 38.452915 Tz (resistant ) Tj 2.027018 0 Td 24.719731 Tz (, ) Tj 0.411996 0 Td 41.199552 Tz (3 ) Tj 0.510874 0 Td 45.59417 Tz (being ) Tj 1.598543 0 Td 48.523916 Tz (mid ) Tj 1.038229 0 Td 19.226457 Tz (- ) Tj 0.197758 0 Td 36.621824 Tz (resistant ) Tj 2.208296 0 Td 37.079596 Tz (to ) Tj 59.350649 0 0 59.350649 0 545.095635 Tm 5.442232 0 Td 42.523705 Tz (genetic ) Tj 1.954486 0 Td 49.61099 Tz (marker ) Tj 1.954486 0 Td 46.334792 Tz (of ) Tj 0.657112 0 Td 42.122538 Tz (the ) Tj 0.926696 0 Td 43.994651 Tz (invention ) Tj 2.527352 0 Td 48.674933 Tz (can ) Tj 1.010941 0 Td 49.142961 Tz (be ) Tj 0.741357 0 Td 42.590566 Tz (useful ) Tj 1.7186 0 Td 40.250425 Tz (for ) Tj 0.876149 0 Td 41.611962 Tz (identifying ) Tj 4.026915 0 Td 38.690331 Tz (partially ) Tj 2.426258 0 Td 40.562444 Tz (resistant ) Tj 2.072429 0 Td 25.273523 Tz (, ) Tj 0.522319 0 Td 44.930708 Tz (4 ) Tj 0.640263 0 Td 46.053975 Tz (being ) Tj 1.7186 0 Td 46.80282 Tz (mid ) Tj 1.061488 0 Td 28.081692 Tz (- ) Tj 0.202188 0 Td 40.846098 Tz (susceptible ) Tj 2.678993 0 Td 28.081692 Tz (, ) Tj 0.539168 0 Td 50.547046 Tz (and ) Tj 1.246827 0 Td 44.930708 Tz (5 ) Tj 0.640263 0 Td 46.053975 Tz (being ) Tj 59.473684 0 0 59.473684 0 504.148613 Tm 5.414159 0 Td 42.035398 Tz (the ) Tj 1.025664 0 Td 45.538348 Tz (presence ) Tj 2.471681 0 Td 47.640118 Tz (of ) Tj 0.790265 0 Td 42.035398 Tz (a ) Tj 0.521239 0 Td 40.742001 Tz (transcription ) Tj 3.446903 0 Td 42.876106 Tz (regulatory ) Tj 2.858407 0 Td 47.239781 Tz (element ) Tj 1.950442 0 Td 25.221239 Tz (, ) Tj 0.453982 0 Td 35.730088 Tz (e.g. ) Tj 0.924779 0 Td 14.011799 Tz (, ) Tj 0.40354 0 Td 42.035398 Tz (a ) Tj 1.546903 0 Td 41.780638 Tz (susceptible ) Tj 2.79115 0 Td 14.011799 Tz (, ) Tj 0.521239 0 Td 45.149131 Tz (according ) Tj 2.824779 0 Td 39.233038 Tz (to ) Tj 0.874336 0 Td 42.035398 Tz (the ) Tj 1.126549 0 Td 46.083251 Tz (numerical ) Tj 2.925664 0 Td 40.353982 Tz (scale ) Tj 1.614159 0 Td 44.526385 Tz (described ) Tj 67.142857 0 0 67.142857 0 459.229258 Tm 4.780851 0 Td 42.819149 Tz (promoter ) Tj 2.323404 0 Td 37.943262 Tz (capable ) Tj 1.846809 0 Td 42.198582 Tz (of ) Tj 0.670213 0 Td 40.026596 Tz (inducing ) Tj 2.159574 0 Td 43.439716 Tz (enhanced ) Tj 2.308511 0 Td 39.468085 Tz (expression ) Tj 2.576596 0 Td 42.198582 Tz (of ) Tj 0.670213 0 Td 33.510638 Tz (dis- ) Tj 1.191489 0 Td 32.269504 Tz (60 ) Tj 0.759574 0 Td 36.406619 Tz (herein ) Tj 1.429787 0 Td 17.375887 Tz (. ) Tj 58.571429 0 0 58.571429 0 418.929904 Tm 5.514634 0 Td 44.817073 Tz (ease ) Tj 1.263415 0 Td 40.97561 Tz (resistance ) Tj 2.526829 0 Td 19.918699 Tz (. ) Tj 0.32439 0 Td 54.065041 Tz (The ) Tj 1.143902 0 Td 41.588493 Tz (transcription ) Tj 3.414634 0 Td 43.536585 Tz (regulatory ) Tj 2.8 0 Td 47.560976 Tz (element ) Tj 2.202439 0 Td 48.373984 Tz (can ) Tj 1.041463 0 Td 49.796748 Tz (be ) Tj 2.543902 0 Td 44.105691 Tz (In ) Tj 0.717073 0 Td 38.699187 Tz (light ) Tj 1.365854 0 Td 48.373984 Tz (of ) Tj 0.7 0 Td 42.682927 Tz (the ) Tj 0.990244 0 Td 47.425474 Tz (impact ) Tj 1.912195 0 Td 48.373984 Tz (of ) Tj 0.717073 0 Td 66.395664 Tz (FHB ) Tj 1.434146 0 Td 52.642276 Tz (on ) Tj 0.802439 0 Td 43.252033 Tz (yield ) Tj 1.314634 0 Td 14.227642 Tz (, ) Tj 0.32439 0 Td 45.528455 Tz (another ) Tj 2.117073 0 Td 43.631436 Tz (aspect ) Tj 1.77561 0 Td 48.373984 Tz (of ) Tj 61 0 0 61 0 376.753676 Tm 5.295082 0 Td 35.519126 Tz (cis ) Tj 0.803279 0 Td 42.349727 Tz (or ) Tj 0.622951 0 Td 38.797814 Tz (trans ) Tj 1.327869 0 Td 39.617486 Tz (in ) Tj 0.590164 0 Td 39.275956 Tz (relation ) Tj 2 0 Td 36.885246 Tz (to ) Tj 0.622951 0 Td 40.983607 Tz (a ) Tj 0.393443 0 Td 47.131148 Tz (gene ) Tj 1.278689 0 Td 44.106167 Tz (capable ) Tj 2 0 Td 46.448087 Tz (of ) Tj 0.639344 0 Td 42.076503 Tz (conferring ) Tj 2.672131 0 Td 41.764247 Tz (disease ) Tj 2.983607 0 Td 40.983607 Tz (the ) Tj 0.901639 0 Td 41.764247 Tz (present ) Tj 1.918033 0 Td 42.197936 Tz (invention ) Tj 2.47541 0 Td 42.691257 Tz (provides ) Tj 2.229508 0 Td 39.617486 Tz (plants ) Tj 1.622951 0 Td 48.269581 Tz (and ) Tj 1.016393 0 Td 40.23845 Tz (derivatives ) Tj 2.819672 0 Td 42.935207 Tz (thereof ) Tj 54.285714 0 0 54.285714 0 336 Tm 5.931579 0 Td 44.824561 Tz (resistance ) Tj 2.689474 0 Td 27.631579 Tz (, ) Tj 0.460526 0 Td 51.425439 Tz (such ) Tj 1.473684 0 Td 44.517544 Tz (as ) Tj 0.810526 0 Td 59.100877 Tz (Fhb1 ) Tj 1.436842 0 Td 21.491228 Tz (. ) Tj 55.714286 0 0 55.714286 0 335.356784 Tm 23.279487 0 Td 50.854701 Tz (of ) Tj 0.735897 0 Td 49.358974 Tz (with ) Tj 1.4 0 Td 44.871795 Tz (a ) Tj 0.466667 0 Td 45.299145 Tz (nucleic ) Tj 2.135897 0 Td 46.367521 Tz (acid ) Tj 1.310256 0 Td 50.480769 Tz (encoding ) Tj 2.638462 0 Td 67.806268 Tz (FHB ) Tj 1.4 0 Td 20.940171 Tz (- ) Tj 0.161538 0 Td 43.376068 Tz (resistance ) Tj 2.8 0 Td 41.132479 Tz (that ) Tj 1.202564 0 Td 44.017094 Tz (exhibit ) Tj 63.308271 0 0 63.308271 0 292.947937 Tm 5.702257 0 Td 39.489311 Tz (In ) Tj 0.647625 0 Td 50.019794 Tz (some ) Tj 1.374228 0 Td 47.626503 Tz (embodiments ) Tj 3.301306 0 Td 39.489311 Tz (the ) Tj 0.884561 0 Td 40.951878 Tz (invention ) Tj 2.353563 0 Td 41.792854 Tz (provides ) Tj 2.17981 0 Td 47.011085 Tz (methods ) Tj 2.164014 0 Td 37.734231 Tz (for ) Tj 1.879691 0 Td 41.244392 Tz (increased ) Tj 2.385154 0 Td 40.542359 Tz (grain ) Tj 1.374228 0 Td 39.489311 Tz (yield ) Tj 1.358432 0 Td 36.85669 Tz (in ) Tj 0.600238 0 Td 39.489311 Tz (the ) Tj 0.884561 0 Td 42.780087 Tz (presence ) Tj 2.242993 0 Td 44.754553 Tz (of ) Tj 0.647625 0 Td 61.427817 Tz (FHB ) Tj 1.311045 0 Td 48.374406 Tz (compared ) Tj 2.479929 0 Td 36.85669 Tz (to ) Tj 0.647625 0 Td 39.489311 Tz (a ) Tj 61.428571 0 0 61.428571 0 250.413472 Tm 5.24186 0 Td 43.410853 Tz (using ) Tj 1.644186 0 Td 41.602067 Tz (the ) Tj 1.090698 0 Td 41.903531 Tz (disclosed ) Tj 2.604651 0 Td 48.158915 Tz (Fhbl ) Tj 1.57907 0 Td 46.802326 Tz (gene ) Tj 1.497674 0 Td 45.445736 Tz (sequence ) Tj 2.539535 0 Td 43.410853 Tz (information ) Tj 3.190698 0 Td 37.984496 Tz (to ) Tj 0.87907 0 Td 33.914729 Tz (65 ) Tj 0.846512 0 Td 40.310078 Tz (control ) Tj 1.904651 0 Td 45.03876 Tz (plant ) Tj 1.204651 0 Td 27.131783 Tz (. ) Tj 62.108844 0 0 62.108844 0 210.281008 Tm 5.200548 0 Td 38.574754 Tz (identify ) Tj 1.980394 0 Td 39.35743 Tz (plants ) Tj 1.577875 0 Td 36.89759 Tz (that ) Tj 1.04655 0 Td 41.785323 Tz (contain ) Tj 1.88379 0 Td 40.251917 Tz (the ) Tj 0.885542 0 Td 47.631435 Tz (Fhbl ) Tj 1.352464 0 Td 46.289704 Tz (gene ) Tj 1.271961 0 Td 38.462943 Tz (for ) Tj 0.821139 0 Td 43.829865 Tz (use ) Tj 0.933844 0 Td 38.910186 Tz (in ) Tj 0.579628 0 Td 43.941676 Tz (breeding ) Tj 3.928587 0 Td 72.45345 Tz (A ) Tj 0.660131 0 Td 41.01862 Tz (nucleic ) Tj 2.012596 0 Td 41.593647 Tz (acid ) Tj 1.25586 0 Td 45.618839 Tz (encoding ) Tj 2.463417 0 Td 62.614093 Tz (FHB ) Tj 1.191457 0 Td 24.15115 Tz (- ) Tj 0.161008 0 Td 39.446878 Tz (resistance ) Tj 2.656627 0 Td 44.277108 Tz (of ) Tj 0.740635 0 Td 40.251917 Tz (the ) Tj 0.982147 0 Td 41.401972 Tz (present ) Tj 59.387755 0 0 59.387755 0 169.557152 Tm 5.405155 0 Td 50.866266 Tz (programs ) Tj 2.374227 0 Td 19.644903 Tz (. ) Tj 0.353608 0 Td 42.719868 Tz (Currently ) Tj 2.34055 0 Td 28.064147 Tz (, ) Tj 0.353608 0 Td 43.850229 Tz (breeders ) Tj 2.290034 0 Td 40.693013 Tz (rely ) Tj 1.178694 0 Td 51.918671 Tz (on ) Tj 0.791409 0 Td 42.09622 Tz (closely ) Tj 1.970103 0 Td 42.898053 Tz (located ) Tj 1.986942 0 Td 51.076747 Tz (mark- ) Tj 2.795189 0 Td 43.967163 Tz (invention ) Tj 2.55945 0 Td 58.934708 Tz (may ) Tj 1.279725 0 Td 47.709049 Tz (be ) Tj 0.791409 0 Td 44.902635 Tz (introduced ) Tj 2.89622 0 Td 38.588202 Tz (into ) Tj 1.178694 0 Td 47.709049 Tz (an ) Tj 0.77457 0 Td 35.360825 Tz (elite ) Tj 1.279725 0 Td 44.434899 Tz (inbred ) Tj 1.78488 0 Td 42.09622 Tz (plant ) Tj 1.481787 0 Td 37.886598 Tz (line ) Tj 0.959794 0 Td 14.032073 Tz (, ) Tj ET Q endstream endobj 191 0 obj << /Length 1 >> stream q endstream endobj 192 0 obj << /Length 51950 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 30 0 0 30 0 2341 Tm 41.5 0 Td 66.666667 Tz (15 ) Tj 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.525 0 Td 74.537037 Tz (23 ) Tj 54.285714 0 0 54.285714 0 2971 Tm 31.702632 0 Td 70.614035 Tz (24 ) Tj 61.428571 0 0 61.428571 0 2913.73223 Tm 5.24186 0 Td 41.511628 Tz (preferably ) Tj 2.653488 0 Td 47.48062 Tz (an ) Tj 0.716279 0 Td 34.186047 Tz (elite ) Tj 1.188372 0 Td 42.958656 Tz (inbred ) Tj 1.676744 0 Td 48.294574 Tz (wheat ) Tj 1.595349 0 Td 37.306202 Tz (line ) Tj 1.05814 0 Td 42.054264 Tz (or ) Tj 0.634884 0 Td 47.48062 Tz (an ) Tj 0.716279 0 Td 34.186047 Tz (elite ) Tj 1.188372 0 Td 42.958656 Tz (inbred ) Tj 1.676744 0 Td 42.054264 Tz (barley ) Tj 2.767442 0 Td 42.732558 Tz (included ) Tj 2.1 0 Td 21.705426 Tz (. ) Tj 0.293023 0 Td 52.906977 Tz (Thus ) Tj 1.188372 0 Td 24.418605 Tz (, ) Tj 0.309302 0 Td 40.697674 Tz (the ) Tj 0.895349 0 Td 41.860465 Tz (present ) Tj 1.937209 0 Td 42.50646 Tz (invention ) Tj 2.45814 0 Td 47.357294 Tz (encompasses ) Tj 3.32093 0 Td 40.697674 Tz (a ) Tj 0.406977 0 Td 39.922481 Tz (variety ) Tj 57.97619 0 0 57.97619 0 2869.985656 Tm 5.571253 0 Td 39.527721 Tz (line ) Tj 1.000411 0 Td 11.498973 Tz (. ) Tj 0.431211 0 Td 66.119097 Tz (An ) Tj 1.155647 0 Td 25.87269 Tz (" ) Tj 0.396715 0 Td 32.197125 Tz (elite ) Tj 1.397125 0 Td 39.527721 Tz (line ) Tj 0.914168 0 Td 34.49692 Tz ( ) Tj 0.638193 0 Td 33.059548 Tz (is ) Tj 0.776181 0 Td 50.787132 Tz (any ) Tj 1.293634 0 Td 38.809035 Tz (line ) Tj 1.293634 0 Td 40.246407 Tz (that ) Tj 1.328131 0 Td 45.995893 Tz (has ) Tj 1.207392 0 Td 42.761807 Tz (resulted ) Tj 2.414784 0 Td 51.026694 Tz (from ) Tj 2.552772 0 Td 48.870637 Tz (of ) Tj 0.724435 0 Td 47.672827 Tz (combinations ) Tj 3.673922 0 Td 47.912389 Tz (and ) Tj 0.948665 0 Td 20.123203 Tz (/ ) Tj 0.22423 0 Td 38.809035 Tz (or ) Tj 0.655441 0 Td 41.92334 Tz (integrations ) Tj 3.24271 0 Td 48.870637 Tz (of ) Tj 0.707187 0 Td 43.12115 Tz (the ) Tj 1.017659 0 Td 39.887064 Tz (specific ) Tj 2.173306 0 Td 57.97399 Tz (embodi ) Tj 57.738095 0 0 57.738095 0 2829.253022 Tm 5.576907 0 Td 46.907216 Tz (breeding ) Tj 2.424742 0 Td 51.958763 Tz (and ) Tj 1.143093 0 Td 41.695304 Tz (selection ) Tj 2.459381 0 Td 40.412371 Tz (for ) Tj 0.900619 0 Td 44.020619 Tz (superior ) Tj 2.286186 0 Td 50.67583 Tz (agronomic ) Tj 2.909691 0 Td 49.597001 Tz (performance ) Tj 3.221443 0 Td 28.865979 Tz (. ) Tj 1.506804 0 Td 50.804124 Tz (ments ) Tj 1.783918 0 Td 45.544101 Tz (described ) Tj 2.684536 0 Td 40.893471 Tz (herein ) Tj 1.610722 0 Td 23.092784 Tz (. ) Tj 64.285714 0 0 64.285714 0 2782.250955 Tm 5.008889 0 Td 59.62963 Tz (An ) Tj 0.886667 0 Td 32.666667 Tz (elite ) Tj 1.151111 0 Td 38.37037 Tz (plant ) Tj 1.337778 0 Td 29.814815 Tz (is ) Tj 0.56 0 Td 38.888889 Tz (a ) Tj 0.404444 0 Td 38.703704 Tz (representative ) Tj 3.422222 0 Td 38.37037 Tz (plant ) Tj 1.337778 0 Td 46.666667 Tz (from ) Tj 1.291111 0 Td 45.37037 Tz (an ) Tj 0.715556 0 Td 32.666667 Tz (elite ) Tj 1.151111 0 Td 37.407407 Tz (variety ) Tj 1.54 0 Td 25.925926 Tz (. ) Tj 62.857143 0 0 62.857143 0 2736.735183 Tm 5.727273 0 Td 60.984848 Tz (An ) Tj 0.859091 0 Td 58.333333 Tz (FHB ) Tj 1.209091 0 Td 18.560606 Tz (- ) Tj 0.175 0 Td 38.181818 Tz (resistance ) Tj 2.434091 0 Td 45.738636 Tz (gene ) Tj 1.240909 0 Td 45.075758 Tz (of ) Tj 0.604545 0 Td 39.772727 Tz (the ) Tj 0.843182 0 Td 40.909091 Tz (present ) Tj 1.861364 0 Td 41.540404 Tz (invention ) Tj 2.354545 0 Td 56.565657 Tz (may ) Tj 1.161364 0 Td 38.44697 Tz (also ) Tj 1.431818 0 Td 29.166667 Tz (5 ) Tj 45.714286 0 0 45.714286 0 2752 Tm 36.028125 0 Td 88.867188 Tz (EXAMPLES ) Tj 60.857143 0 0 60.857143 0 2695.161549 Tm 5.29108 0 Td 47.926448 Tz (be ) Tj 0.85446 0 Td 43.544601 Tz (introduced ) Tj 2.875587 0 Td 38.341158 Tz (into ) Tj 1.215962 0 Td 47.926448 Tz (an ) Tj 0.838028 0 Td 34.507042 Tz (elite ) Tj 1.298122 0 Td 40.532081 Tz (plant ) Tj 1.495305 0 Td 45.735524 Tz (comprising ) Tj 3.023474 0 Td 48.38289 Tz (one ) Tj 1.150235 0 Td 41.079812 Tz (or ) Tj 0.739437 0 Td 52.719092 Tz (more ) Tj 63.035714 0 0 63.035714 0 2655.015803 Tm 5.092351 0 Td 41.246459 Tz (transgenes ) Tj 2.76034 0 Td 40.717658 Tz (conferring ) Tj 2.68102 0 Td 40.835169 Tz (herbicide ) Tj 2.443059 0 Td 40.247613 Tz (tolerance ) Tj 2.205099 0 Td 13.220019 Tz (, ) Tj 0.364873 0 Td 41.422726 Tz (increased ) Tj 2.458924 0 Td 39.660057 Tz (yield ) Tj 1.22153 0 Td 13.220019 Tz (, ) Tj 1.935411 0 Td 50.236072 Tz (The ) Tj 1.110482 0 Td 42.010282 Tz (following ) Tj 2.474788 0 Td 45.939566 Tz (examples ) Tj 2.443059 0 Td 34.372049 Tz (set ) Tj 0.809065 0 Td 38.073654 Tz (forth ) Tj 1.316714 0 Td 47.214353 Tz (methods ) Tj 2.205099 0 Td 37.016053 Tz (in ) Tj 0.634561 0 Td 44.154863 Tz (accordance ) Tj 54.880952 0 0 54.880952 0 2611.531646 Tm 5.885466 0 Td 43.528561 Tz (insect ) Tj 1.913232 0 Td 45.986985 Tz (control ) Tj 1.87679 0 Td 27.331887 Tz (, ) Tj 0.528416 0 Td 47.071584 Tz (fungal ) Tj 2.059002 0 Td 45.986985 Tz (disease ) Tj 2.259436 0 Td 44.642082 Tz (resistance ) Tj 2.733189 0 Td 15.184382 Tz (, ) Tj 0.43731 0 Td 44.94577 Tz (virus ) Tj 1.676356 0 Td 44.642082 Tz (resistance ) Tj 2.733189 0 Td 15.184382 Tz (, ) Tj 1.512364 0 Td 50.867679 Tz (with ) Tj 1.348373 0 Td 45.553145 Tz (the ) Tj 1.002169 0 Td 45.215715 Tz (invention ) Tj 2.550976 0 Td 21.258134 Tz (. ) Tj 0.327983 0 Td 33.40564 Tz (It ) Tj 0.564859 0 Td 33.40564 Tz (is ) Tj 0.58308 0 Td 40.997831 Tz (to ) Tj 0.655965 0 Td 53.145336 Tz (be ) Tj 0.783514 0 Td 50.10846 Tz (understood ) Tj 3.006508 0 Td 27.331887 Tz (, ) Tj 0.346204 0 Td 55.531453 Tz (however ) Tj 2.277657 0 Td 27.331887 Tz (, ) Tj 0.346204 0 Td 42.516269 Tz (that ) Tj 1.166161 0 Td 46.160521 Tz (these ) Tj 62.605042 0 0 62.605042 0 2566.902627 Tm 5.143356 0 Td 48.252237 Tz (nematode ) Tj 2.667517 0 Td 39.400447 Tz (resistance ) Tj 2.332081 0 Td 23.959732 Tz (, ) Tj 0.511141 0 Td 38.158091 Tz (bacterial ) Tj 2.411946 0 Td 40.693512 Tz (disease ) Tj 2.060537 0 Td 38.33557 Tz (resistance ) Tj 2.316107 0 Td 23.959732 Tz (, ) Tj 0.543087 0 Td 51.646532 Tz (myco- ) Tj 2.715436 0 Td 46.255593 Tz (examples ) Tj 2.491812 0 Td 39.045488 Tz (are ) Tj 0.942416 0 Td 44.258949 Tz (provided ) Tj 2.364027 0 Td 47.919463 Tz (by ) Tj 0.830604 0 Td 54.131245 Tz (way ) Tj 1.245906 0 Td 43.926174 Tz (of ) Tj 0.718792 0 Td 35.717748 Tz (illustration ) Tj 2.827248 0 Td 47.032066 Tz (and ) Tj 1.086174 0 Td 42.975391 Tz (nothing ) Tj 70.714286 0 0 70.714286 0 2523.297084 Tm 4.539394 0 Td 40.460157 Tz (plasma ) Tj 1.640404 0 Td 35.690236 Tz (disease ) Tj 1.640404 0 Td 34.646465 Tz (resistance ) Tj 2.121212 0 Td 11.784512 Tz (, ) Tj 0.254545 0 Td 38.594276 Tz (modified ) Tj 1.993939 0 Td 30.050505 Tz (oils ) Tj 0.933333 0 Td 37.239057 Tz (production ) Tj 2.234343 0 Td 32.996633 Tz (, ) Tj 0.254545 0 Td 39.478114 Tz (high ) Tj 1.088889 0 Td 29.854097 Tz (oil ) Tj 0.905051 0 Td 29.461279 Tz (10 ) Tj 0.707071 0 Td 35.016835 Tz (therein ) Tj 1.59798 0 Td 37.710438 Tz (should ) Tj 1.49899 0 Td 40.06734 Tz (be ) Tj 0.608081 0 Td 38.181818 Tz (taken ) Tj 1.258586 0 Td 34.175084 Tz (as ) Tj 0.551515 0 Td 30.639731 Tz (a ) Tj 0.367677 0 Td 33.703704 Tz (limitation ) Tj 2.121212 0 Td 43.602694 Tz (upon ) Tj 1.187879 0 Td 33.782267 Tz (the ) Tj 0.749495 0 Td 34.006734 Tz (overall ) Tj 1.583838 0 Td 39.124579 Tz (scope ) Tj 58.021978 0 0 58.021978 0 2483.931335 Tm 5.532386 0 Td 45.672348 Tz (production ) Tj 2.757576 0 Td 28.724747 Tz (, ) Tj 0.413636 0 Td 45.959596 Tz (high ) Tj 1.344318 0 Td 42.676768 Tz (protein ) Tj 2.033712 0 Td 45.097854 Tz (production ) Tj 2.723106 0 Td 28.724747 Tz (, ) Tj 0.413636 0 Td 47.004132 Tz (germination ) Tj 3.309091 0 Td 49.789562 Tz (and ) Tj 1.240909 0 Td 43.087121 Tz (seed- ) Tj 2.585227 0 Td 48.832071 Tz (of ) Tj 0.741098 0 Td 43.087121 Tz (the ) Tj 1.016856 0 Td 43.406285 Tz (invention ) Tj 2.395644 0 Td 22.979798 Tz (. ) Tj 58.571429 0 0 58.571429 0 2433.795567 Tm 5.514634 0 Td 40.54878 Tz (ling ) Tj 1.195122 0 Td 49.796748 Tz (growth ) Tj 2.014634 0 Td 45.121951 Tz (control ) Tj 1.758537 0 Td 25.609756 Tz (, ) Tj 0.409756 0 Td 49.796748 Tz (enhanced ) Tj 2.595122 0 Td 47.425474 Tz (animal ) Tj 1.946341 0 Td 50.271003 Tz (and ) Tj 1.109756 0 Td 58.04878 Tz (human ) Tj 1.929268 0 Td 39.837398 Tz (nutrition ) Tj 2.219512 0 Td 25.609756 Tz (, ) Tj 57.142857 0 0 57.142857 0 2389 Tm 5.6525 0 Td 52.5 Tz (low ) Tj 1.4175 0 Td 41.481481 Tz (raffinose ) Tj 2.205 0 Td 26.25 Tz (, ) Tj 0.6825 0 Td 48.012821 Tz (environmental ) Tj 4.2525 0 Td 38.888889 Tz (stress ) Tj 1.8725 0 Td 42.12963 Tz (resistant ) Tj 2.1525 0 Td 26.25 Tz (, ) Tj 0.665 0 Td 45.694444 Tz (increased ) Tj 47.142857 0 0 47.142857 0 2407 Tm 35.063636 0 Td 54.503367 Tz (Introduction ) Tj 61.428571 0 0 61.428571 0 2348.222086 Tm 5.25814 0 Td 36.73226 Tz (digestibility ) Tj 2.832558 0 Td 27.131783 Tz (, ) Tj 0.488372 0 Td 37.713178 Tz (industrial ) Tj 2.588372 0 Td 51.162791 Tz (enzymes ) Tj 2.148837 0 Td 18.992248 Tz (, ) Tj 0.423256 0 Td 43.992248 Tz (pharmaceutical ) Tj 4.004651 0 Td 40.358527 Tz (proteins ) Tj 2.002326 0 Td 13.565891 Tz (, ) Tj 60 0 0 60 0 2306.822642 Tm 5.366667 0 Td 43.055556 Tz (peptides ) Tj 2.333333 0 Td 50 Tz (and ) Tj 1.166667 0 Td 43.333333 Tz (small ) Tj 1.6 0 Td 45.679012 Tz (molecules ) Tj 2.5 0 Td 25 Tz (, ) Tj 0.433333 0 Td 49.305556 Tz (improved ) Tj 2.633333 0 Td 44.444444 Tz (processing ) Tj 2.9 0 Td 32.87037 Tz (traits ) Tj 1.266667 0 Td 25 Tz (, ) Tj 55.714286 0 0 55.714286 0 2313.973545 Tm 23.907692 0 Td 54.220085 Tz (Fusarium ) Tj 2.835897 0 Td 58.333333 Tz (Head ) Tj 1.579487 0 Td 45.868946 Tz (Blight ) Tj 1.866667 0 Td 29.91453 Tz (\( ) Tj 0.215385 0 Td 69.80057 Tz (FHB ) Tj 1.310256 0 Td 29.91453 Tz (\) ) Tj 0.233333 0 Td 14.957265 Tz (, ) Tj 0.323077 0 Td 43.376068 Tz (also ) Tj 1.238462 0 Td 61.025641 Tz (known ) Tj 2.010256 0 Td 43.376068 Tz (as ) Tj 0.717949 0 Td 53.247863 Tz (wheat ) Tj 1.812821 0 Td 47.115385 Tz (scab ) Tj 1.202564 0 Td 14.957265 Tz (, ) Tj 61.428571 0 0 61.428571 0 2258.803946 Tm 5.25814 0 Td 48.498062 Tz (improved ) Tj 2.539535 0 Td 38.888889 Tz (flavor ) Tj 1.367442 0 Td 24.418605 Tz (, ) Tj 0.374419 0 Td 42.393411 Tz (nitrogen ) Tj 2.246512 0 Td 36.967054 Tz (fixation ) Tj 1.823256 0 Td 24.418605 Tz (, ) Tj 0.374419 0 Td 44.315245 Tz (hybrid ) Tj 1.839535 0 Td 44.089147 Tz (seed ) Tj 1.253488 0 Td 42.596899 Tz (production ) Tj 2.588372 0 Td 27.131783 Tz (, ) Tj 55.714286 0 0 55.714286 0 2271.652658 Tm 23.279487 0 Td 32.905983 Tz (is ) Tj 0.592308 0 Td 44.871795 Tz (a ) Tj 0.430769 0 Td 49.358974 Tz (very ) Tj 1.364103 0 Td 44.327894 Tz (destructive ) Tj 3.105128 0 Td 45.299145 Tz (disease ) Tj 2.1 0 Td 49.358974 Tz (of ) Tj 0.682051 0 Td 55.641026 Tz (wheat ) Tj 1.597436 0 Td 26.923077 Tz (, ) Tj 0.341026 0 Td 53.846154 Tz (and ) Tj 1.130769 0 Td 44.871795 Tz (limited ) Tj 2.064103 0 Td 46.581197 Tz (sources ) Tj 2.153846 0 Td 50.854701 Tz (of ) Tj 64.285714 0 0 64.285714 0 2217.065868 Tm 5.008889 0 Td 44.074074 Tz (reduced ) Tj 1.991111 0 Td 36.894587 Tz (allergenicity ) Tj 2.831111 0 Td 25.925926 Tz (, ) Tj 0.311111 0 Td 43.602694 Tz (biopolymers ) Tj 2.94 0 Td 12.962963 Tz (, ) Tj 0.264444 0 Td 45.802469 Tz (and ) Tj 0.964444 0 Td 38.564815 Tz (biofuels ) Tj 2.022222 0 Td 51.851852 Tz (among ) Tj 1.742222 0 Td 50.987654 Tz (oth ) Tj 57.142857 0 0 57.142857 0 2227.116779 Tm 22.68 0 Td 42.875 Tz (resistance ) Tj 2.905 0 Td 42.777778 Tz (are ) Tj 1.1025 0 Td 59.5 Tz (known ) Tj 2.1175 0 Td 43.333333 Tz (against ) Tj 2.1525 0 Td 29.166667 Tz (it ) Tj 0.4025 0 Td 11.666667 Tz (. ) Tj 0.4375 0 Td 53.472222 Tz (Hot ) Tj 1.295 0 Td 52.5 Tz (and ) Tj 1.2425 0 Td 56 Tz (humid ) Tj 1.995 0 Td 49.583333 Tz (weather ) Tj 55.595238 0 0 55.595238 0 2172.223404 Tm 5.791863 0 Td 40.970735 Tz (ers ) Tj 0.827409 0 Td 11.991435 Tz (. ) Tj 0.395717 0 Td 43.468951 Tz (In ) Tj 0.75546 0 Td 52.96217 Tz (one ) Tj 1.205139 0 Td 45.967166 Tz (aspect ) Tj 1.708779 0 Td 14.989293 Tz (, ) Tj 0.359743 0 Td 44.96788 Tz (the ) Tj 1.079229 0 Td 45.634071 Tz (herbicide ) Tj 2.734047 0 Td 45.300975 Tz (tolerance ) Tj 2.71606 0 Td 32.976445 Tz (is ) Tj 0.683512 0 Td 43.843683 Tz (selected ) Tj 2.392291 0 Td 53.211991 Tz (from ) Tj 57.142857 0 0 57.142857 0 2185.001304 Tm 22.6975 0 Td 44.625 Tz (conditions ) Tj 2.9575 0 Td 37.916667 Tz (at ) Tj 0.7175 0 Td 43.020833 Tz (anthesis ) Tj 2.345 0 Td 42.777778 Tz (are ) Tj 1.0325 0 Td 47.25 Tz (conducible ) Tj 3.115 0 Td 41.805556 Tz (for ) Tj 0.98 0 Td 43.75 Tz (the ) Tj 1.0675 0 Td 46.666667 Tz (spread ) Tj 1.925 0 Td 49.583333 Tz (of ) Tj 0.7525 0 Td 44.722222 Tz (the ) Tj 64.285714 0 0 64.285714 0 2129.134872 Tm 5.008889 0 Td 38.888889 Tz (the ) Tj 0.98 0 Td 44.074074 Tz (group ) Tj 1.617778 0 Td 38.888889 Tz (consisting ) Tj 2.613333 0 Td 44.074074 Tz (of ) Tj 0.746667 0 Td 41.481481 Tz (glyphosate ) Tj 2.457778 0 Td 25.925926 Tz (, ) Tj 0.466667 0 Td 47.037037 Tz (dicamba ) Tj 1.928889 0 Td 23.333333 Tz (, ) Tj 0.451111 0 Td 39.124579 Tz (glufosinate ) Tj 2.551111 0 Td 25.925926 Tz (, ) Tj 0.528889 0 Td 35 Tz (20 ) Tj 60 0 0 60 0 2139.859606 Tm 21.616667 0 Td 42.063492 Tz (disease ) Tj 1.816667 0 Td 13.888889 Tz (, ) Tj 0.283333 0 Td 44.444444 Tz (during ) Tj 1.766667 0 Td 51.111111 Tz (which ) Tj 1.683333 0 Td 46.990741 Tz (macroconidia ) Tj 3.566667 0 Td 44.444444 Tz (spread ) Tj 1.766667 0 Td 36.111111 Tz (at ) Tj 0.583333 0 Td 45.833333 Tz (very ) Tj 1.266667 0 Td 36.805556 Tz (fast ) Tj 1.05 0 Td 38.333333 Tz (rates ) Tj 61.285714 0 0 61.285714 0 2091.827889 Tm 5.270396 0 Td 41.472416 Tz (sulfonylurea ) Tj 2.986014 0 Td 27.195027 Tz (, ) Tj 0.342657 0 Td 47.047397 Tz (bromoxynil ) Tj 3.034965 0 Td 48.044548 Tz (and ) Tj 1.011655 0 Td 42.770361 Tz (norflurazon ) Tj 2.986014 0 Td 41.336441 Tz (herbicides ) Tj 2.512821 0 Td 21.756022 Tz (. ) Tj 0.310023 0 Td 47.863248 Tz (These ) Tj 2.708625 0 Td 43.900544 Tz (causing ) Tj 2.088578 0 Td 41.880342 Tz (rapid ) Tj 1.517483 0 Td 45.022878 Tz (secondary ) Tj 2.692308 0 Td 39.97669 Tz (infections ) Tj 2.398601 0 Td 19.036519 Tz (. ) Tj 0.391608 0 Td 51.670552 Tz (The ) Tj 1.191142 0 Td 16.317016 Tz ( ) Tj 0.146853 0 Td 53.710179 Tz (Fhbl ) Tj 1.615385 0 Td 63.455063 Tz (QTL ) Tj 1.272727 0 Td 27.195027 Tz ( ) Tj 0.424242 0 Td 29.91453 Tz (is ) Tj 0.652681 0 Td 40.792541 Tz (a ) Tj 64.285714 0 0 64.285714 0 2040.118959 Tm 5.008889 0 Td 31.54321 Tz (traits ) Tj 1.337778 0 Td 44.074074 Tz (can ) Tj 0.933333 0 Td 45.37037 Tz (be ) Tj 0.7 0 Td 43.425926 Tz (provided ) Tj 2.224444 0 Td 47.962963 Tz (by ) Tj 0.731111 0 Td 46.666667 Tz (methods ) Tj 2.146667 0 Td 44.074074 Tz (of ) Tj 0.622222 0 Td 38.37037 Tz (plant ) Tj 1.306667 0 Td 42.678063 Tz (biotechnology ) Tj 3.5 0 Td 37.592593 Tz (as ) Tj 56.507937 0 0 56.507937 0 2054.893696 Tm 22.934831 0 Td 43.01264 Tz (quantitative ) Tj 3.291573 0 Td 35.393258 Tz (trait ) Tj 1.274157 0 Td 44.831461 Tz (locus ) Tj 1.575 0 Td 53.089888 Tz (from ) Tj 1.46882 0 Td 50.140449 Tz (Chinese ) Tj 2.318258 0 Td 50.877809 Tz (Landrace ) Tj 2.672191 0 Td 53.581461 Tz (Sumai3 ) Tj 1.999719 0 Td 11.797753 Tz (' ) Tj 0.283146 0 Td 41.292135 Tz (that ) Tj 48.571429 0 0 48.571429 0 2002.728916 Tm 6.608824 0 Td 53.872549 Tz (transgenes ) Tj 3.211765 0 Td 30.882353 Tz (. ) Tj 62.857143 0 0 62.857143 0 2008.652913 Tm 20.618182 0 Td 42.092803 Tz (provides ) Tj 2.211364 0 Td 38.977273 Tz (resistance ) Tj 2.497727 0 Td 35.795455 Tz (to ) Tj 0.620455 0 Td 39.772727 Tz (the ) Tj 0.922727 0 Td 42.424242 Tz (spread ) Tj 1.686364 0 Td 45.075758 Tz (of ) Tj 0.620455 0 Td 48.058712 Tz (Fusarium ) Tj 2.465909 0 Td 48.932507 Tz (graminearum ) Tj 50 0 0 50 0 1957 Tm 7.2 0 Td 76.666667 Tz (An ) Tj 1.28 0 Td 76.666667 Tz (FHB ) Tj 1.54 0 Td 23.333333 Tz (- ) Tj 0.24 0 Td 47.666667 Tz (resistance ) Tj 3.24 0 Td 44.444444 Tz (allele ) Tj 2 0 Td 50 Tz (or ) Tj 0.98 0 Td 44.285714 Tz (alleles ) Tj 2.28 0 Td 56.666667 Tz (can ) Tj 1.38 0 Td 58.333333 Tz (be ) Tj 1.08 0 Td 53.333333 Tz (introduced ) Tj 57.142857 0 0 57.142857 0 1963.733668 Tm 22.6975 0 Td 41.481481 Tz (infection ) Tj 2.31 0 Td 20.416667 Tz (. ) Tj 0.385 0 Td 59.305556 Tz (Due ) Tj 1.295 0 Td 39.375 Tz (to ) Tj 0.735 0 Td 42.583333 Tz (large ) Tj 1.5225 0 Td 51.527778 Tz (and ) Tj 1.155 0 Td 43.166667 Tz (consistent ) Tj 2.835 0 Td 44.236111 Tz (contribution ) Tj 3.395 0 Td 48.75 Tz (towards ) Tj 71.904762 0 0 71.904762 0 1911.31965 Tm 4.50596 0 Td 33.609272 Tz (from ) Tj 1.265563 0 Td 41.721854 Tz (any ) Tj 0.97351 0 Td 36.622517 Tz (plant ) Tj 1.376821 0 Td 32.450331 Tz (that ) Tj 1.070861 0 Td 35.637417 Tz (contains ) Tj 2.002649 0 Td 33.029801 Tz (that ) Tj 1.084768 0 Td 30.905077 Tz (allele ) Tj 1.418543 0 Td 32.450331 Tz (\( ) Tj 0.166887 0 Td 40.331126 Tz (donor ) Tj 1.209934 0 Td 25.496689 Tz (\) ) Tj 0.445033 0 Td 32.450331 Tz (to ) Tj 0.695364 0 Td 41.721854 Tz (any ) Tj 1.070861 0 Td 31.291391 Tz (25 ) Tj 0.723179 0 Td 34.304636 Tz (resistance ) Tj 2.266887 0 Td 34.768212 Tz (against ) Tj 1.682781 0 Td 37.086093 Tz (scab ) Tj 0.931788 0 Td 13.907285 Tz (, ) Tj 0.292053 0 Td 36.313466 Tz (the ) Tj 0.862252 0 Td 41.721854 Tz (Fhb1 ) Tj 1.265563 0 Td 55.629139 Tz (QTL ) Tj 1.196026 0 Td 26.655629 Tz (is ) Tj 0.528477 0 Td 35.540839 Tz (the ) Tj 0.834437 0 Td 42.301325 Tz (most ) Tj 1.209934 0 Td 39.403974 Tz (widely ) Tj 64.285714 0 0 64.285714 0 1868.634686 Tm 5.008889 0 Td 37.736626 Tz (recipient ) Tj 2.177778 0 Td 41.481481 Tz (plant ) Tj 1.135556 0 Td 25.925926 Tz (. ) Tj 0.326667 0 Td 40.185185 Tz (In ) Tj 0.637778 0 Td 44.938272 Tz (one ) Tj 0.98 0 Td 39.753086 Tz (aspect ) Tj 1.462222 0 Td 12.962963 Tz (, ) Tj 0.264444 0 Td 38.888889 Tz (the ) Tj 0.84 0 Td 37.736626 Tz (recipient ) Tj 2.177778 0 Td 38.888889 Tz (plant ) Tj 1.322222 0 Td 44.074074 Tz (can ) Tj 0.948889 0 Td 40.740741 Tz (contain ) Tj 64.285714 0 0 64.285714 0 1877.175127 Tm 20.16 0 Td 44.722222 Tz (used ) Tj 1.306667 0 Td 41.049383 Tz (source ) Tj 1.726667 0 Td 42.777778 Tz (of ) Tj 0.684444 0 Td 38.111111 Tz (resistance ) Tj 2.52 0 Td 36.296296 Tz (in ) Tj 0.653333 0 Td 42.12963 Tz (breeding ) Tj 2.255556 0 Td 47.962963 Tz (programs ) Tj 2.224444 0 Td 18.148148 Tz (. ) Tj 0.326667 0 Td 44.592593 Tz (There ) Tj 1.571111 0 Td 38.888889 Tz (are ) Tj 57.142857 0 0 57.142857 0 1820.982644 Tm 5.6525 0 Td 51.041667 Tz (an ) Tj 0.9275 0 Td 42.875 Tz (additional ) Tj 2.9225 0 Td 68.055556 Tz (FHB ) Tj 1.295 0 Td 26.25 Tz (- ) Tj 0.175 0 Td 42.875 Tz (resistance ) Tj 2.9225 0 Td 38.645833 Tz (loci ) Tj 1.015 0 Td 11.666667 Tz (. ) Tj 0.4375 0 Td 43.75 Tz (In ) Tj 0.84 0 Td 46.666667 Tz (another ) Tj 2.275 0 Td 44.722222 Tz (aspect ) Tj 1.6625 0 Td 14.583333 Tz (, ) Tj 0.4375 0 Td 43.75 Tz (the ) Tj 58.571429 0 0 58.571429 0 1832.476923 Tm 22.126829 0 Td 51.930894 Tz (numerous ) Tj 2.765854 0 Td 38.211382 Tz (strains ) Tj 1.843902 0 Td 48.373984 Tz (of ) Tj 0.7 0 Td 47.662602 Tz (Fusarium ) Tj 2.526829 0 Td 25.609756 Tz (, ) Tj 0.341463 0 Td 45.528455 Tz (but ) Tj 1.02439 0 Td 42.682927 Tz (the ) Tj 1.007317 0 Td 50.50813 Tz (Fhb1 ) Tj 1.519512 0 Td 67.344173 Tz (QTL ) Tj 1.4 0 Td 45.528455 Tz (provides ) Tj 57.142857 0 0 57.142857 0 1780.568475 Tm 5.635 0 Td 42.453704 Tz (recipient ) Tj 2.5375 0 Td 43.75 Tz (plant ) Tj 1.5925 0 Td 49.583333 Tz (can ) Tj 1.155 0 Td 45.416667 Tz (contain ) Tj 2.17 0 Td 43.75 Tz (a ) Tj 0.525 0 Td 46.342593 Tz (transgene ) Tj 2.485 0 Td 26.25 Tz (. ) Tj 0.455 0 Td 45.208333 Tz (In ) Tj 0.805 0 Td 46.666667 Tz (another ) Tj 2.205 0 Td 45.208333 Tz (aspect ) Tj 1.6625 0 Td 14.583333 Tz (, ) Tj 62.857143 0 0 62.857143 0 1787.233681 Tm 20.618182 0 Td 39.772727 Tz (horizontal ) Tj 2.672727 0 Td 38.977273 Tz (resistance ) Tj 2.609091 0 Td 39.772727 Tz (against ) Tj 1.940909 0 Td 30.934343 Tz (all ) Tj 0.827273 0 Td 39.772727 Tz (the ) Tj 1.002273 0 Td 36.458333 Tz (isolates ) Tj 2.036364 0 Td 45.075758 Tz (of ) Tj 0.795455 0 Td 43.087121 Tz (Fusarium ) Tj 2.338636 0 Td 26.515152 Tz (, ) Tj 65.714286 0 0 65.714286 0 1729.238994 Tm 4.9 0 Td 42.101449 Tz (while ) Tj 1.491304 0 Td 41.040843 Tz (maintaining ) Tj 2.936957 0 Td 38.043478 Tz (the ) Tj 0.928261 0 Td 40.326087 Tz (introduced ) Tj 2.647826 0 Td 58.333333 Tz (FHB ) Tj 1.217391 0 Td 17.753623 Tz (- ) Tj 0.106522 0 Td 36.521739 Tz (resistance ) Tj 2.434783 0 Td 33.39372 Tz (allele ) Tj 1.445652 0 Td 39.311594 Tz (or ) Tj 60 0 0 60 0 1749.433779 Tm 21.6 0 Td 41.358025 Tz (therefore ) Tj 2.416667 0 Td 42.777778 Tz (screenings ) Tj 2.733333 0 Td 39.814815 Tz (for ) Tj 0.85 0 Td 64.814815 Tz (FHB ) Tj 1.333333 0 Td 40.833333 Tz (resistance ) Tj 2.6 0 Td 40.740741 Tz (are ) Tj 0.883333 0 Td 49.305556 Tz (done ) Tj 1.316667 0 Td 45 Tz (using ) Tj 1.5 0 Td 36.574074 Tz (fairly ) Tj 79.495798 0 0 79.495798 0 1694.360239 Tm 4.050529 0 Td 28.153629 Tz (alleles ) Tj 1.207611 0 Td 14.675828 Tz (, ) Tj 0.276744 0 Td 34.942448 Tz (the ) Tj 0.754757 0 Td 32.346723 Tz (genetic ) Tj 1.547252 0 Td 31.97234 Tz (contribution ) Tj 2.478118 0 Td 36.68957 Tz (of ) Tj 0.566068 0 Td 32.147052 Tz (the ) Tj 0.754757 0 Td 31.028894 Tz (plant ) Tj 1.119556 0 Td 33.777699 Tz (providing ) Tj 2.012685 0 Td 32.147052 Tz (the ) Tj 0.86797 0 Td 29.351656 Tz (30 ) Tj 0.666702 0 Td 32.915786 Tz (aggressive ) Tj 2.151057 0 Td 28.453136 Tz (strains ) Tj 1.371142 0 Td 36.68957 Tz (of ) Tj 0.52833 0 Td 30.39993 Tz (F. ) Tj 0.540909 0 Td 37.166058 Tz (graminearum ) Tj 2.591332 0 Td 23.062016 Tz (. ) Tj 62.857143 0 0 62.857143 0 1644.782067 Tm 5.138636 0 Td 40.530303 Tz (disease ) Tj 1.877273 0 Td 38.977273 Tz (resistance ) Tj 2.529545 0 Td 45.075758 Tz (can ) Tj 0.970455 0 Td 46.401515 Tz (be ) Tj 0.731818 0 Td 44.69697 Tz (reduced ) Tj 2.052273 0 Td 47.727273 Tz (by ) Tj 0.763636 0 Td 46.401515 Tz (back ) Tj 1.145455 0 Td 23.863636 Tz (- ) Tj 0.190909 0 Td 40.767045 Tz (crossing ) Tj 2.147727 0 Td 39.772727 Tz (or ) Tj 0.652273 0 Td 40.833333 Tz (other ) Tj 58.571429 0 0 58.571429 0 1666.807377 Tm 22.792683 0 Td 46.476965 Tz (Screening ) Tj 2.782927 0 Td 41.734417 Tz (for ) Tj 0.973171 0 Td 41.829268 Tz (resistance ) Tj 2.765854 0 Td 39.837398 Tz (to ) Tj 0.768293 0 Td 65.447154 Tz (FHB ) Tj 1.485366 0 Td 31.300813 Tz (is ) Tj 0.665854 0 Td 42.682927 Tz (a ) Tj 0.512195 0 Td 44.817073 Tz (resource ) Tj 2.42439 0 Td 42.366757 Tz (intensive ) Tj 58.571429 0 0 58.571429 0 1604.5 Tm 5.531707 0 Td 40.54878 Tz (suitable ) Tj 2.339024 0 Td 48.089431 Tz (approaches ) Tj 2.817073 0 Td 28.455285 Tz (. ) Tj 0.597561 0 Td 42.682927 Tz (In ) Tj 0.904878 0 Td 49.322493 Tz (one ) Tj 1.280488 0 Td 43.631436 Tz (aspect ) Tj 1.621951 0 Td 14.227642 Tz (, ) Tj 0.495122 0 Td 42.682927 Tz (the ) Tj 1.143902 0 Td 45.121951 Tz (nuclear ) Tj 2.270732 0 Td 43.089431 Tz (genetic ) Tj 67.142857 0 0 67.142857 0 1617.844417 Tm 19.317021 0 Td 37.544326 Tz (exercise ) Tj 1.980851 0 Td 44.680851 Tz (and ) Tj 0.953191 0 Td 41.702128 Tz (needs ) Tj 1.429787 0 Td 34.751773 Tz (to ) Tj 0.595745 0 Td 43.439716 Tz (be ) Tj 0.7 0 Td 36.489362 Tz (replicated ) Tj 2.368085 0 Td 40.957447 Tz (over ) Tj 1.146809 0 Td 34.475965 Tz (different ) Tj 2.055319 0 Td 36.406619 Tz (locations ) Tj 2.025532 0 Td 12.411348 Tz (, ) Tj 57.142857 0 0 57.142857 0 1558.749367 Tm 5.635 0 Td 44.114583 Tz (material ) Tj 2.345 0 Td 46.25 Tz (derived ) Tj 2.135 0 Td 51.770833 Tz (from ) Tj 1.4175 0 Td 43.75 Tz (the ) Tj 0.9975 0 Td 50.166667 Tz (donor ) Tj 1.68 0 Td 44.114583 Tz (material ) Tj 2.3275 0 Td 42.291667 Tz (in ) Tj 0.665 0 Td 43.75 Tz (the ) Tj 0.98 0 Td 43.166667 Tz (plant ) Tj 1.4875 0 Td 50.555556 Tz (can ) Tj 1.0675 0 Td 51.041667 Tz (be ) Tj 65.714286 0 0 65.714286 0 1581 Tm 19.721739 0 Td 37.653289 Tz (necessitating ) Tj 3.286957 0 Td 44.806763 Tz (marker ) Tj 1.704348 0 Td 17.753623 Tz (- ) Tj 0.167391 0 Td 35.507246 Tz (assisted ) Tj 2.084783 0 Td 36.916264 Tz (selection ) Tj 2.358696 0 Td 35.507246 Tz (in ) Tj 0.776087 0 Td 41.213768 Tz (breeding ) Tj 2.38913 0 Td 51.570048 Tz (pro ) Tj 74.89011 0 0 74.89011 0 1500.84355 Tm 4.299633 0 Td 31.156762 Tz (less ) Tj 0.867938 0 Td 37.27684 Tz (than ) Tj 1.01482 0 Td 34.494987 Tz (or ) Tj 0.547469 0 Td 37.388114 Tz (about ) Tj 1.255172 0 Td 41.171436 Tz (50 ) Tj 0.494057 0 Td 68.989973 Tz (% ) Tj 0.41394 0 Td 15.578381 Tz (, ) Tj 0.253705 0 Td 31.156762 Tz (less ) Tj 0.867938 0 Td 36.72047 Tz (than ) Tj 1.01482 0 Td 35.607728 Tz (or ) Tj 0.534116 0 Td 39.168501 Tz (about ) Tj 1.308584 0 Td 41.171436 Tz (25 ) Tj 0.560822 0 Td 35.607728 Tz (% ) Tj 0.333822 0 Td 35.607728 Tz (, ) Tj 0.307117 0 Td 29.48765 Tz (less ) Tj 0.881291 0 Td 32.825874 Tz (than ) Tj 0.92135 0 Td 35.607728 Tz (or ) Tj 0.734409 0 Td 30.044021 Tz (35 ) Tj 0.694351 0 Td 32.746393 Tz (perfect ) Tj 1.615701 0 Td 37.833211 Tz (markers ) Tj 1.856053 0 Td 32.640417 Tz (for ) Tj 0.801174 0 Td 30.954445 Tz (utilization ) Tj 2.363463 0 Td 23.367572 Tz (in ) Tj 0.520763 0 Td 36.72047 Tz (breeding ) Tj 1.949523 0 Td 40.058694 Tz (programs ) Tj 2.163169 0 Td 40.800522 Tz (and ) Tj 65.714286 0 0 65.714286 0 1540.859085 Tm 19.736957 0 Td 47.681159 Tz (grams ) Tj 1.369565 0 Td 17.753623 Tz (. ) Tj 0.319565 0 Td 43.115942 Tz (Cloning ) Tj 1.993478 0 Td 43.115942 Tz (of ) Tj 0.623913 0 Td 45.652174 Tz (Fhbl ) Tj 1.33913 0 Td 43.75 Tz (gene ) Tj 1.232609 0 Td 32.971014 Tz (facilitates ) Tj 2.343478 0 Td 38.043478 Tz (the ) Tj 0.867391 0 Td 44.268775 Tz (development ) Tj 3.104348 0 Td 43.115942 Tz (of ) Tj 55.714286 0 0 55.714286 0 1471 Tm 5.797436 0 Td 49.059829 Tz (about ) Tj 1.758974 0 Td 46.367521 Tz (13 ) Tj 0.610256 0 Td 86.752137 Tz (% ) Tj 0.574359 0 Td 14.957265 Tz (, ) Tj 0.358974 0 Td 40.384615 Tz (less ) Tj 1.202564 0 Td 48.611111 Tz (than ) Tj 1.382051 0 Td 46.367521 Tz (or ) Tj 0.771795 0 Td 49.059829 Tz (about ) Tj 1.723077 0 Td 41.880342 Tz (5 ) Tj 0.305128 0 Td 86.752137 Tz (% ) Tj 0.592308 0 Td 14.957265 Tz (, ) Tj 0.358974 0 Td 44.871795 Tz (3 ) Tj 0.323077 0 Td 86.752137 Tz (% ) Tj 0.592308 0 Td 14.957265 Tz (, ) Tj 0.341026 0 Td 47.863248 Tz (2 ) Tj 0.341026 0 Td 86.752137 Tz (% ) Tj 0.771795 0 Td 46.367521 Tz (or ) Tj 0.825641 0 Td 29.91453 Tz (1 ) Tj 0.269231 0 Td 86.752137 Tz (% ) Tj 0.592308 0 Td 14.957265 Tz (, ) Tj 0.341026 0 Td 46.866097 Tz (but ) Tj 1.058974 0 Td 41.880342 Tz (that ) Tj 63.809524 0 0 63.809524 0 1459.367105 Tm 20.310448 0 Td 45.05597 Tz (gene ) Tj 1.347761 0 Td 44.925373 Tz (pyramiding ) Tj 2.977612 0 Td 37.437811 Tz (for ) Tj 0.940299 0 Td 39.701493 Tz (increasing ) Tj 2.648507 0 Td 39.179104 Tz (the ) Tj 0.987313 0 Td 37.089552 Tz (level ) Tj 1.410448 0 Td 43.097015 Tz (of ) Tj 0.736567 0 Td 38.395522 Tz (resistance ) Tj 2.570149 0 Td 36.567164 Tz (in ) Tj 60 0 0 60 0 1429.195489 Tm 5.383333 0 Td 42.063492 Tz (genetic ) Tj 1.966667 0 Td 42.013889 Tz (material ) Tj 2.233333 0 Td 42.361111 Tz (contains ) Tj 2.233333 0 Td 41.666667 Tz (the ) Tj 0.95 0 Td 64.814815 Tz (FHB ) Tj 1.3 0 Td 19.444444 Tz (- ) Tj 0.166667 0 Td 40 Tz (resistance ) Tj 2.6 0 Td 42.222222 Tz (locus ) Tj 1.483333 0 Td 47.222222 Tz (of ) Tj 0.783333 0 Td 40.555556 Tz (inter ) Tj 61.428571 0 0 61.428571 0 1415.849568 Tm 21.113953 0 Td 44.918174 Tz (germplasm ) Tj 2.669767 0 Td 27.131783 Tz (. ) Tj 0.309302 0 Td 45.706619 Tz (Understanding ) Tj 3.727907 0 Td 46.124031 Tz (of ) Tj 0.618605 0 Td 40.697674 Tz (the ) Tj 0.87907 0 Td 55.620155 Tz (mode ) Tj 1.497674 0 Td 46.124031 Tz (of ) Tj 0.634884 0 Td 41.149871 Tz (action ) Tj 1.627907 0 Td 44.767442 Tz (of ) Tj 0.618605 0 Td 40.697674 Tz (the ) Tj 0.895349 0 Td 46.802326 Tz (gene ) Tj 38.571429 0 0 38.571429 0 1390 Tm 8.374074 0 Td 56.17284 Tz (est ) Tj 1.140741 0 Td 17.283951 Tz (. ) Tj 58.571429 0 0 58.571429 0 1375.557089 Tm 22.126829 0 Td 40.54878 Tz (will ) Tj 1.160976 0 Td 49.796748 Tz (be ) Tj 0.768293 0 Td 46.95122 Tz (very ) Tj 1.297561 0 Td 42.682927 Tz (useful ) Tj 1.741463 0 Td 40.785908 Tz (for ) Tj 0.904878 0 Td 49.638663 Tz (combating ) Tj 2.885366 0 Td 44.817073 Tz (scab ) Tj 1.280488 0 Td 39.837398 Tz (in ) Tj 0.64878 0 Td 53.495935 Tz (wheat ) Tj 1.485366 0 Td 25.609756 Tz (, ) Tj 0.358537 0 Td 43.631436 Tz (barley ) Tj 1.502439 0 Td 28.455285 Tz (, ) Tj 0.392683 0 Td 50.271003 Tz (and ) Tj 56.923077 0 0 56.923077 0 1339.850049 Tm 6.341892 0 Td 43.918919 Tz (In ) Tj 0.878378 0 Td 56.362613 Tz (some ) Tj 1.704054 0 Td 53.767404 Tz (embodiments ) Tj 3.513514 0 Td 26.351351 Tz (, ) Tj 0.491892 0 Td 42.942943 Tz (plants ) Tj 1.914865 0 Td 45.968468 Tz (containing ) Tj 3.109459 0 Td 50.750751 Tz (one ) Tj 1.282432 0 Td 43.918919 Tz (or ) Tj 0.843243 0 Td 56.362613 Tz (more ) Tj 2.705405 0 Td 44.504505 Tz (other ) Tj 1.563514 0 Td 43.186937 Tz (affected ) Tj 2.301351 0 Td 43.500644 Tz (cereals ) Tj 1.844595 0 Td 20.495495 Tz (. ) Tj 57.142857 0 0 57.142857 0 1294.518782 Tm 5.6525 0 Td 68.055556 Tz (FHB ) Tj 1.295 0 Td 26.25 Tz (- ) Tj 0.175 0 Td 42.875 Tz (resistance ) Tj 2.7825 0 Td 39.375 Tz (loci ) Tj 1.1725 0 Td 49.583333 Tz (can ) Tj 1.085 0 Td 40.833333 Tz (act ) Tj 0.945 0 Td 40.833333 Tz (as ) Tj 0.7175 0 Td 50.75 Tz (donor ) Tj 1.6975 0 Td 43.263889 Tz (plants ) Tj 1.505 0 Td 29.166667 Tz (. ) Tj 0.42 0 Td 43.263889 Tz (Plants ) Tj 1.82 0 Td 44.114583 Tz (contain- ) Tj 4.0775 0 Td 44.074074 Tz (Resistant ) Tj 2.66 0 Td 51.527778 Tz (and ) Tj 1.225 0 Td 43.219697 Tz (susceptible ) Tj 3.1325 0 Td 47.395833 Tz (near ) Tj 1.4 0 Td 44.479167 Tz (isogenic ) Tj 2.4325 0 Td 39.666667 Tz (lines ) Tj 1.47 0 Td 52.5 Tz (were ) Tj 1.54 0 Td 49.583333 Tz (used ) Tj 59.166667 0 0 59.166667 0 1252.496565 Tm 5.459155 0 Td 43.192488 Tz (ing ) Tj 0.946479 0 Td 65.7277 Tz (FHB ) Tj 1.250704 0 Td 25.352113 Tz (- ) Tj 0.169014 0 Td 41.408451 Tz (resistance ) Tj 2.653521 0 Td 38.028169 Tz (loci ) Tj 1.08169 0 Td 47.887324 Tz (can ) Tj 0.997183 0 Td 49.295775 Tz (be ) Tj 0.642254 0 Td 14.084507 Tz (, ) Tj 0.270423 0 Td 40.375587 Tz (for ) Tj 0.878873 0 Td 50.301811 Tz (example ) Tj 2.078873 0 Td 28.169014 Tz (, ) Tj 0.371831 0 Td 45.422535 Tz (screened ) Tj 2.332394 0 Td 40.375587 Tz (for ) Tj 0.861972 0 Td 52.112676 Tz (by ) Tj 1.926761 0 Td 40.375587 Tz (for ) Tj 0.895775 0 Td 48.591549 Tz (gene ) Tj 1.352113 0 Td 45.070423 Tz (expression ) Tj 2.890141 0 Td 40.241449 Tz (studies ) Tj 1.892958 0 Td 49.765258 Tz (due ) Tj 1.064789 0 Td 38.028169 Tz (to ) Tj 0.642254 0 Td 42.253521 Tz (the ) Tj 0.980282 0 Td 39.43662 Tz (similarity ) Tj 2.569014 0 Td 46.478873 Tz (expected ) Tj 2.4 0 Td 39.43662 Tz (in ) Tj 60 0 0 60 0 1210.294737 Tm 5.366667 0 Td 44.444444 Tz (using ) Tj 1.533333 0 Td 41.666667 Tz (a ) Tj 0.416667 0 Td 42.460317 Tz (nucleic ) Tj 1.983333 0 Td 43.055556 Tz (acid ) Tj 1.183333 0 Td 47.569444 Tz (molecule ) Tj 2.466667 0 Td 44.84127 Tz (capable ) Tj 2.066667 0 Td 47.222222 Tz (of ) Tj 0.683333 0 Td 41.975309 Tz (detecting ) Tj 2.45 0 Td 41.666667 Tz (a ) Tj 0.416667 0 Td 49.537037 Tz (marker ) Tj 3.033333 0 Td 38.333333 Tz (their ) Tj 1.316667 0 Td 42.063492 Tz (genetic ) Tj 1.95 0 Td 47.777778 Tz (background ) Tj 2.883333 0 Td 27.777778 Tz (. ) Tj 0.383333 0 Td 51.851852 Tz (The ) Tj 1.133333 0 Td 41.414141 Tz (susceptible ) Tj 2.9 0 Td 57.407407 Tz (NIL ) Tj 1.183333 0 Td 51.851852 Tz (was ) Tj 1.133333 0 Td 48.333333 Tz (found ) Tj 1.6 0 Td 37.5 Tz (to ) Tj 58.571429 0 0 58.571429 0 1166.9952 Tm 5.497561 0 Td 48.373984 Tz (of ) Tj 0.734146 0 Td 51.693767 Tz (polymorphism ) Tj 3.943902 0 Td 43.821138 Tz (associated ) Tj 2.834146 0 Td 46.95122 Tz (with ) Tj 1.34878 0 Td 41.260163 Tz (resistance ) Tj 2.509756 0 Td 22.764228 Tz (. ) Tj 61.428571 0 0 61.428571 0 1166.853403 Tm 21.097674 0 Td 47.48062 Tz (be ) Tj 0.797674 0 Td 44.96124 Tz (missing ) Tj 2.116279 0 Td 35.949612 Tz (this ) Tj 1.123256 0 Td 45.445736 Tz (gene ) Tj 1.139535 0 Td 18.992248 Tz (, ) Tj 0.374419 0 Td 46.899225 Tz (whereas ) Tj 2.230233 0 Td 43.410853 Tz (expression ) Tj 2.832558 0 Td 46.124031 Tz (of ) Tj 0.716279 0 Td 40.697674 Tz (the ) Tj 0.993023 0 Td 46.802326 Tz (gene ) Tj 1.351163 0 Td 51.550388 Tz (was ) Tj 59.485714 0 0 59.485714 0 1121.73427 Tm 6.068684 0 Td 42.026897 Tz (In ) Tj 0.739673 0 Td 48.564415 Tz (one ) Tj 1.126321 0 Td 43.427794 Tz (or ) Tj 0.722863 0 Td 53.23407 Tz (more ) Tj 1.529779 0 Td 51.451111 Tz (embodiments ) Tj 3.378963 0 Td 25.216138 Tz (, ) Tj 0.369837 0 Td 42.026897 Tz (the ) Tj 1.008646 0 Td 43.894759 Tz (invention ) Tj 2.588857 0 Td 32.220621 Tz (is ) Tj 0.638809 0 Td 40.626001 Tz (also ) Tj 1.361671 0 Td 43.427794 Tz (con- ) Tj 2.269452 0 Td 48.751201 Tz (found ) Tj 1.613833 0 Td 39.225104 Tz (to ) Tj 0.689241 0 Td 42.377121 Tz (increase ) Tj 2.202209 0 Td 51.833173 Tz (by ) Tj 0.806916 0 Td 48.564415 Tz (two ) Tj 1.008646 0 Td 19.612552 Tz (- ) Tj 0.252161 0 Td 37.824207 Tz (fold ) Tj 1.092699 0 Td 39.225104 Tz (in ) Tj 0.638809 0 Td 42.026897 Tz (the ) Tj 0.941402 0 Td 38.602483 Tz (resistant ) Tj 2.269452 0 Td 56.969794 Tz (NIL ) Tj 1.075889 0 Td 14.008966 Tz (, ) Tj 0.319404 0 Td 47.630484 Tz (96 ) Tj 0.773295 0 Td 45.949408 Tz (hours ) Tj 60 0 0 60 0 1082.713654 Tm 5.383333 0 Td 45.833333 Tz (cerned ) Tj 1.85 0 Td 46.527778 Tz (with ) Tj 1.333333 0 Td 41.666667 Tz (a ) Tj 0.45 0 Td 44.047619 Tz (process ) Tj 2.1 0 Td 47.222222 Tz (of ) Tj 0.7 0 Td 46.604938 Tz (producing ) Tj 2.766667 0 Td 45.138889 Tz (seed ) Tj 1.133333 0 Td 11.111111 Tz (. ) Tj 0.316667 0 Td 43.055556 Tz (In ) Tj 0.733333 0 Td 53.472222 Tz (some ) Tj 1.516667 0 Td 48.412698 Tz (embodi- ) Tj 2.433333 0 Td 37.5 Tz (45 ) Tj 0.9 0 Td 37.777778 Tz (after ) Tj 1.5 0 Td 42.171717 Tz (inoculation ) Tj 2.833333 0 Td 11.111111 Tz (. ) Tj 0.45 0 Td 53.819444 Tz (Numerous ) Tj 2.95 0 Td 42.65873 Tz (transcriptomic ) Tj 4 0 Td 39.68254 Tz (studies ) Tj 2.05 0 Td 48.611111 Tz (have ) Tj 60.785714 0 0 60.785714 0 1042.493097 Tm 5.297297 0 Td 47.160204 Tz (ments ) Tj 1.447709 0 Td 21.934978 Tz (, ) Tj 0.427732 0 Td 42.042042 Tz (the ) Tj 1.019976 0 Td 51.181616 Tz (method ) Tj 2.122209 0 Td 45.393219 Tz (comprises ) Tj 2.763807 0 Td 36.329808 Tz (self ) Tj 0.93772 0 Td 27.418723 Tz (- ) Tj 0.180964 0 Td 39.632518 Tz (pollination ) Tj 2.878966 0 Td 46.611829 Tz (of ) Tj 0.773208 0 Td 41.128085 Tz (a ) Tj 0.592244 0 Td 38.777908 Tz (geneti- ) Tj 2.878966 0 Td 48.668233 Tz (been ) Tj 1.46416 0 Td 48.668233 Tz (done ) Tj 1.480611 0 Td 39.30017 Tz (for ) Tj 1.003525 0 Td 40.629562 Tz (identifying ) Tj 2.977673 0 Td 41.128085 Tz (the ) Tj 1.052879 0 Td 43.260652 Tz (candidate ) Tj 2.648649 0 Td 47.297297 Tz (gene ) Tj 1.431257 0 Td 50.724638 Tz (by ) Tj 0.904818 0 Td 42.694869 Tz (various ) Tj 55.396825 0 0 55.396825 0 1002.960549 Tm 5.830659 0 Td 42.120344 Tz (cally ) Tj 1.389971 0 Td 30.08596 Tz (- ) Tj 0.108309 0 Td 50.770057 Tz (modified ) Tj 3.086819 0 Td 44.527221 Tz (plant ) Tj 2.021777 0 Td 42.120344 Tz (as ) Tj 1.209456 0 Td 47.803247 Tz (described ) Tj 3.231232 0 Td 43.123209 Tz (herein ) Tj 1.678797 0 Td 21.060172 Tz (. ) Tj 0.848424 0 Td 45.12894 Tz (In ) Tj 62.857143 0 0 62.857143 0 1000.199243 Tm 20.634091 0 Td 43.75 Tz (groups ) Tj 1.75 0 Td 42.424242 Tz (using ) Tj 1.431818 0 Td 40.30303 Tz (these ) Tj 1.352273 0 Td 48.611111 Tz (two ) Tj 1.034091 0 Td 43.087121 Tz (near ) Tj 1.193182 0 Td 40.435606 Tz (isogenic ) Tj 2.115909 0 Td 36.060606 Tz (lines ) Tj 1.161364 0 Td 10.606061 Tz (. ) Tj 0.254545 0 Td 50.378788 Tz (Most ) Tj 1.368182 0 Td 45.075758 Tz (of ) Tj 0.620455 0 Td 39.772727 Tz (the ) Tj 0.875 0 Td 45.738636 Tz (gene ) Tj 58.646617 0 0 58.646617 0 959.505516 Tm 5.507564 0 Td 51.412199 Tz (embodiments ) Tj 3.46141 0 Td 14.209402 Tz (, ) Tj 0.375128 0 Td 42.628205 Tz (the ) Tj 1.023077 0 Td 53.048433 Tz (method ) Tj 2.182564 0 Td 47.048908 Tz (comprises ) Tj 2.847564 0 Td 43.69391 Tz (crossing ) Tj 2.370128 0 Td 42.628205 Tz (a ) Tj 0.52859 0 Td 32.397436 Tz (first ) Tj 1.227692 0 Td 41.491453 Tz (plant ) Tj 2.574744 0 Td 45.185897 Tz (expression ) Tj 2.966923 0 Td 41.004274 Tz (studies ) Tj 1.977949 0 Td 40.733618 Tz (for ) Tj 0.971923 0 Td 66.310541 Tz (FHB ) Tj 1.449359 0 Td 49.732906 Tz (have ) Tj 1.432308 0 Td 50.443376 Tz (been ) Tj 1.449359 0 Td 48.311966 Tz (conducted ) Tj 2.830513 0 Td 49.732906 Tz (up ) Tj 0.852564 0 Td 39.786325 Tz (to ) Tj 0.767308 0 Td 46.891026 Tz (96 ) Tj 60.571429 0 0 60.571429 0 916.489145 Tm 5.316038 0 Td 46.088836 Tz (with ) Tj 1.403302 0 Td 41.273585 Tz (a ) Tj 0.57783 0 Td 46.77673 Tz (second ) Tj 1.964623 0 Td 44.025157 Tz (plant ) Tj 1.188679 0 Td 27.515723 Tz (, ) Tj 0.495283 0 Td 47.169811 Tz (wherein ) Tj 2.278302 0 Td 35.77044 Tz (at ) Tj 0.742925 0 Td 36.871069 Tz (least ) Tj 1.419811 0 Td 47.69392 Tz (one ) Tj 1.17217 0 Td 46.77673 Tz (of ) Tj 0.775943 0 Td 42.190776 Tz (the ) Tj 1.073113 0 Td 30.81761 Tz (first ) Tj 1.238208 0 Td 42.649371 Tz (or ) Tj 1.75 0 Td 45.125786 Tz (hours ) Tj 1.601415 0 Td 45.400943 Tz (post ) Tj 1.089623 0 Td 27.515723 Tz (- ) Tj 0.198113 0 Td 39.772727 Tz (inoculation ) Tj 2.674528 0 Td 27.515723 Tz (, ) Tj 0.462264 0 Td 39.897799 Tz (as ) Tj 0.726415 0 Td 42.190776 Tz (the ) Tj 1.007075 0 Td 43.107966 Tz (fungal ) Tj 1.816038 0 Td 48.152516 Tz (growth ) Tj 1.981132 0 Td 31.643082 Tz (is ) Tj 0.643868 0 Td 40.585692 Tz (arrested ) Tj 2.195755 0 Td 35.77044 Tz (at ) Tj 62.857143 0 0 62.857143 0 875.199725 Tm 5.154545 0 Td 45.075758 Tz (second ) Tj 2.084091 0 Td 38.888889 Tz (plants ) Tj 1.909091 0 Td 30.492424 Tz (is ) Tj 0.875 0 Td 39.772727 Tz (a ) Tj 0.731818 0 Td 37.844353 Tz (genetically ) Tj 2.640909 0 Td 26.515152 Tz (- ) Tj 0.095455 0 Td 45.407197 Tz (modified ) Tj 2.640909 0 Td 39.772727 Tz (plant ) Tj 1.654545 0 Td 45.075758 Tz (having ) Tj 2.004545 0 Td 35.795455 Tz (50 ) Tj 0.843182 0 Td 43.484848 Tz (about ) Tj 1.511364 0 Td 39.772727 Tz (the ) Tj 0.954545 0 Td 49.05303 Tz (same ) Tj 1.384091 0 Td 42.424242 Tz (period ) Tj 1.734091 0 Td 36.060606 Tz (after ) Tj 1.288636 0 Td 38.888889 Tz (infection ) Tj 2.322727 0 Td 37.121212 Tz (in ) Tj 0.636364 0 Td 36.531987 Tz (resistant ) Tj 2.195455 0 Td 36.060606 Tz (lines ) Tj 1.161364 0 Td 10.606061 Tz (. ) Tj 58.968254 0 0 58.968254 0 835.67074 Tm 5.477524 0 Td 44.279946 Tz (increased ) Tj 2.730283 0 Td 42.799462 Tz (disease ) Tj 2.153701 0 Td 40.982503 Tz (resistance ) Tj 2.475908 0 Td 25.437416 Tz (, ) Tj 0.508748 0 Td 40.51144 Tz (particularly ) Tj 3.255989 0 Td 47.341857 Tz (with ) Tj 1.47537 0 Td 42.395693 Tz (respect ) Tj 2.119785 0 Td 39.569314 Tz (to ) Tj 2.425034 0 Td 59.35397 Tz (TILLING ) Tj 2.526783 0 Td 14.131898 Tz (, ) Tj 0.288291 0 Td 51.440108 Tz (which ) Tj 1.712786 0 Td 32.503365 Tz (is ) Tj 0.576581 0 Td 42.395693 Tz (a ) Tj 0.423957 0 Td 47.341857 Tz (powerful ) Tj 2.45895 0 Td 43.20323 Tz (reverse ) Tj 2.001077 0 Td 42.395693 Tz (genetic ) Tj 1.96716 0 Td 45.536115 Tz (technique ) Tj 2.441992 0 Td 28.263795 Tz (, ) Tj 55 0 0 55 0 791.877646 Tm 5.872727 0 Td 70.707071 Tz (FHB ) Tj 1.345455 0 Td 15.151515 Tz (, ) Tj 0.4 0 Td 43.939394 Tz (as ) Tj 0.836364 0 Td 47.811448 Tz (described ) Tj 2.836364 0 Td 43.939394 Tz (herein ) Tj 1.709091 0 Td 21.212121 Tz (. ) Tj 0.436364 0 Td 46.969697 Tz (In ) Tj 0.854545 0 Td 57.575758 Tz (some ) Tj 1.672727 0 Td 54.820937 Tz (embodiments ) Tj 3.618182 0 Td 27.272727 Tz (, ) Tj 0.454545 0 Td 45.454545 Tz (the ) Tj 1.109091 0 Td 34.545455 Tz (first ) Tj 2.418182 0 Td 57.575758 Tz (was ) Tj 1.309091 0 Td 52.272727 Tz (used ) Tj 1.509091 0 Td 42.424242 Tz (to ) Tj 0.8 0 Td 44.69697 Tz (validate ) Tj 2.4 0 Td 46.464646 Tz (the ) Tj 1.109091 0 Td 50 Tz (cloned ) Tj 2.072727 0 Td 53.787879 Tz (gene ) Tj 1.272727 0 Td 21.212121 Tz (, ) Tj 0.436364 0 Td 51.082251 Tz (because ) Tj 2.418182 0 Td 51.515152 Tz (of ) Tj 0.818182 0 Td 45.454545 Tz (the ) Tj 1.090909 0 Td 63.636364 Tz (uni ) Tj 58.809524 0 0 58.809524 0 752.83759 Tm 5.492308 0 Td 50.067476 Tz (and ) Tj 1.309312 0 Td 48.178138 Tz (second ) Tj 2.091498 0 Td 41.565452 Tz (plants ) Tj 1.921457 0 Td 41.565452 Tz (are ) Tj 1.122267 0 Td 47.469636 Tz (both ) Tj 1.51336 0 Td 41.994847 Tz (genetically ) Tj 3.145749 0 Td 47.115385 Tz (modified ) Tj 2.635628 0 Td 41.565452 Tz (plants ) Tj 2.805668 0 Td 44.534413 Tz (formity ) Tj 2.125506 0 Td 48.178138 Tz (of ) Tj 0.765182 0 Td 42.510121 Tz (genetic ) Tj 2.040486 0 Td 50.161943 Tz (background ) Tj 3.247773 0 Td 46.761134 Tz (of ) Tj 0.731174 0 Td 42.510121 Tz (the ) Tj 1.003239 0 Td 47.368421 Tz (mutants ) Tj 2.261538 0 Td 50.067476 Tz (and ) Tj 1.139271 0 Td 43.319838 Tz (control ) Tj 1.785425 0 Td 22.672065 Tz (. ) Tj 62.142857 0 0 62.142857 0 710.202618 Tm 5.181609 0 Td 45.146871 Tz (having ) Tj 1.834483 0 Td 42.01788 Tz (increased ) Tj 2.462069 0 Td 40.229885 Tz (disease ) Tj 1.818391 0 Td 24.137931 Tz (- ) Tj 0.177011 0 Td 38.084291 Tz (resistance ) Tj 2.301149 0 Td 24.137931 Tz (, ) Tj 0.354023 0 Td 38.888889 Tz (as ) Tj 0.691954 0 Td 42.613878 Tz (described ) Tj 2.478161 0 Td 39.782886 Tz (herein ) Tj 1.512644 0 Td 18.773946 Tz (. ) Tj 0.337931 0 Td 41.570881 Tz (In ) Tj 1.721839 0 Td 42.911877 Tz (Ethyl ) Tj 1.448276 0 Td 48.275862 Tz (methane ) Tj 2.236782 0 Td 42.911877 Tz (sulphonate ) Tj 2.767816 0 Td 26.819923 Tz (\( ) Tj 0.193103 0 Td 66.155811 Tz (EMS ) Tj 1.23908 0 Td 26.819923 Tz (\) ) Tj 0.354023 0 Td 30.842912 Tz (is ) Tj 0.57931 0 Td 45.59387 Tz (an ) Tj 0.724138 0 Td 39.693487 Tz (alkylating ) Tj 2.574713 0 Td 42.911877 Tz (agent ) Tj 1.464368 0 Td 47.381865 Tz (and ) Tj 58.571429 0 0 58.571429 0 666.866579 Tm 5.514634 0 Td 50.271003 Tz (one ) Tj 1.07561 0 Td 42.682927 Tz (or ) Tj 0.665854 0 Td 54.065041 Tz (more ) Tj 1.468293 0 Td 50.960828 Tz (embodiments ) Tj 3.431707 0 Td 25.609756 Tz (, ) Tj 0.307317 0 Td 42.682927 Tz (the ) Tj 0.939024 0 Td 32.439024 Tz (first ) Tj 1.143902 0 Td 50.271003 Tz (and ) Tj 1.092683 0 Td 48.373984 Tz (second ) Tj 1.878049 0 Td 41.734417 Tz (plants ) Tj 1.690244 0 Td 49.322493 Tz (can ) Tj 1.02439 0 Td 49.796748 Tz (be ) Tj 1.007317 0 Td 36.99187 Tz (55 ) Tj 0.887805 0 Td 45.528455 Tz (has ) Tj 1.058537 0 Td 50.50813 Tz (been ) Tj 1.417073 0 Td 44.461382 Tz (reported ) Tj 2.356098 0 Td 38.414634 Tz (to ) Tj 0.7 0 Td 47.899729 Tz (mostly ) Tj 1.980488 0 Td 46.097561 Tz (cause ) Tj 1.621951 0 Td 34.146341 Tz (G ) Tj 0.597561 0 Td 19.918699 Tz (> ) Tj 0.341463 0 Td 19.918699 Tz (A ) Tj 0.358537 0 Td 19.918699 Tz (/ ) Tj 0.273171 0 Td 19.918699 Tz (C ) Tj 0.426829 0 Td 19.918699 Tz (> ) Tj 0.460976 0 Td 25.609756 Tz (T ) Tj 0.37561 0 Td 39.837398 Tz (transitions ) Tj 2.885366 0 Td 39.837398 Tz (in ) Tj 61.964286 0 0 61.964286 0 624.889441 Tm 5.21268 0 Td 43.035543 Tz (crossed ) Tj 1.920461 0 Td 40.345821 Tz (via ) Tj 0.887608 0 Td 40.345821 Tz (cross ) Tj 1.339481 0 Td 26.897214 Tz (- ) Tj 0.112968 0 Td 39.367741 Tz (pollination ) Tj 2.711239 0 Td 43.573487 Tz (using ) Tj 1.45245 0 Td 38.424592 Tz (insects ) Tj 1.791354 0 Td 26.897214 Tz (\( ) Tj 0.19366 0 Td 33.621518 Tz (e.g. ) Tj 0.887608 0 Td 13.448607 Tz (, ) Tj 0.258213 0 Td 32.276657 Tz (flies ) Tj 1.129683 0 Td 39.000961 Tz (in ) Tj 0.613256 0 Td 39.807877 Tz (cloth ) Tj 2.404611 0 Td 47.877041 Tz (wheat ) Tj 1.484726 0 Td 10.758886 Tz (. ) Tj 0.29049 0 Td 51.104707 Tz (Our ) Tj 1.081268 0 Td 36.887608 Tz (results ) Tj 1.742939 0 Td 45.725264 Tz (of ) Tj 0.645533 0 Td 41.242395 Tz (the ) Tj 0.903746 0 Td 56.48415 Tz (TILLING ) Tj 2.549856 0 Td 44.918348 Tz (experiment ) Tj 2.856484 0 Td 48.414986 Tz (were ) Tj 1.35562 0 Td 38.32853 Tz (also ) Tj 1.129683 0 Td 39.000961 Tz (in ) Tj 58.986175 0 0 58.986175 0 585.571328 Tm 5.458906 0 Td 45.773438 Tz (cages ) Tj 1.407109 0 Td 28.255208 Tz (\) ) Tj 0.237344 0 Td 14.127604 Tz (, ) Tj 0.440781 0 Td 51.330295 Tz (manual ) Tj 2.220859 0 Td 33.90625 Tz (\( ) Tj 0.152578 0 Td 50.859375 Tz (hand ) Tj 1.271484 0 Td 28.255208 Tz (\) ) Tj 0.525547 0 Td 41.612216 Tz (pollination ) Tj 2.780312 0 Td 14.127604 Tz (, ) Tj 0.457734 0 Td 48.975694 Tz (and ) Tj 1.220625 0 Td 42.382812 Tz (the ) Tj 1.118906 0 Td 38.144531 Tz (like ) Tj 0.983281 0 Td 11.302083 Tz (. ) Tj 0.440781 0 Td 46.015625 Tz (Genetic ) Tj 3.255 0 Td 49.289641 Tz (agreement ) Tj 2.627734 0 Td 22.604167 Tz (, ) Tj 0.457734 0 Td 39.557292 Tz (as ) Tj 0.779844 0 Td 45.208333 Tz (not ) Tj 1.101953 0 Td 49.446615 Tz (even ) Tj 1.491875 0 Td 42.382813 Tz (a ) Tj 0.576406 0 Td 40.499132 Tz (single ) Tj 1.746172 0 Td 43.324653 Tz (transversion ) Tj 3.424531 0 Td 33.90625 Tz (\( ) Tj 0.220391 0 Td 28.255208 Tz (G ) Tj 0.559453 0 Td 28.255208 Tz (> ) Tj 0.423828 0 Td 28.255208 Tz (T ) Tj 0.27125 0 Td 28.255208 Tz (/ ) Tj 0.203437 0 Td 28.255208 Tz (C ) Tj 0.423828 0 Td 28.255208 Tz (> ) Tj 0.406875 0 Td 28.255208 Tz (A ) Tj 0.305156 0 Td 28.255208 Tz (\) ) Tj 59.571429 0 0 59.571429 0 543.498409 Tm 5.405276 0 Td 44.297895 Tz (modification ) Tj 3.340528 0 Td 48.494538 Tz (can ) Tj 1.023981 0 Td 47.56195 Tz (be ) Tj 0.755396 0 Td 41.966427 Tz (cisgenic ) Tj 2.215827 0 Td 43.365308 Tz (or ) Tj 0.654676 0 Td 41.127098 Tz (transgenic ) Tj 2.534772 0 Td 27.977618 Tz (, ) Tj 0.369305 0 Td 43.365308 Tz (or ) Tj 0.671463 0 Td 41.966427 Tz (the ) Tj 0.923261 0 Td 45.563549 Tz (product ) Tj 2.081535 0 Td 47.56195 Tz (of ) Tj 1.779376 0 Td 53.157474 Tz (was ) Tj 1.292566 0 Td 47.21223 Tz (observed ) Tj 2.568345 0 Td 40.567546 Tz (in ) Tj 0.772182 0 Td 41.966427 Tz (the ) Tj 1.107914 0 Td 47.872813 Tz (sequenced ) Tj 2.88729 0 Td 47.16227 Tz (mutants ) Tj 2.014388 0 Td 16.786571 Tz (. ) Tj 0.402878 0 Td 44.204636 Tz (After ) Tj 1.661871 0 Td 43.520739 Tz (screening ) Tj 57.857143 0 0 57.857143 0 508.19774 Tm 5.548148 0 Td 51.131687 Tz (gene ) Tj 1.469136 0 Td 43.621399 Tz (editing ) Tj 61.428571 0 0 61.428571 0 500.391361 Tm 21.162791 0 Td 46.802326 Tz (1932 ) Tj 1.383721 0 Td 40.245478 Tz (plants ) Tj 1.4 0 Td 27.131783 Tz (, ) Tj 0.455814 0 Td 47.48062 Tz (40 ) Tj 0.813953 0 Td 45.348837 Tz (mutants ) Tj 2.148837 0 Td 49.515504 Tz (were ) Tj 1.432558 0 Td 38.255814 Tz (identified ) Tj 2.506977 0 Td 45.445736 Tz (with ) Tj 1.334884 0 Td 40.697674 Tz (a ) Tj 0.488372 0 Td 44.186047 Tz (product ) Tj 2.1 0 Td 46.124031 Tz (of ) Tj 64.285714 0 0 64.285714 0 457.23301 Tm 5.6 0 Td 41.222222 Tz (Additional ) Tj 2.644444 0 Td 42.518519 Tz (advantages ) Tj 2.753333 0 Td 42.777778 Tz (of ) Tj 0.622222 0 Td 38.888889 Tz (the ) Tj 0.855556 0 Td 40.37037 Tz (various ) Tj 1.882222 0 Td 46.902357 Tz (embodiments ) Tj 3.297778 0 Td 42.777778 Tz (of ) Tj 0.622222 0 Td 38.888889 Tz (the ) Tj 1.088889 0 Td 33.703704 Tz (60 ) Tj 0.824444 0 Td 44.938272 Tz (926 ) Tj 1.12 0 Td 45.37037 Tz (bp ) Tj 0.606667 0 Td 12.962963 Tz (, ) Tj 0.404444 0 Td 40.617284 Tz (giving ) Tj 1.757778 0 Td 44.074074 Tz (an ) Tj 0.824444 0 Td 42.222222 Tz (average ) Tj 2.053333 0 Td 43.425926 Tz (mutation ) Tj 2.364444 0 Td 42.633745 Tz (frequency ) Tj 2.597778 0 Td 44.074074 Tz (of ) Tj 0.808889 0 Td 25.925926 Tz (1 ) Tj 0.217778 0 Td 25.925926 Tz (/ ) Tj 0.186667 0 Td 40.185185 Tz (39.9 ) Tj 57.888199 0 0 57.888199 0 417.565703 Tm 5.579721 0 Td 45.106104 Tz (invention ) Tj 2.6603 0 Td 41.027361 Tz (will ) Tj 1.243777 0 Td 50.384478 Tz (be ) Tj 0.863734 0 Td 46.065808 Tz (apparent ) Tj 2.453004 0 Td 38.868026 Tz (to ) Tj 0.742811 0 Td 44.914163 Tz (those ) Tj 1.62382 0 Td 40.307582 Tz (skilled ) Tj 1.952039 0 Td 40.307582 Tz (in ) Tj 0.725536 0 Td 43.186695 Tz (the ) Tj 1.036481 0 Td 36.468765 Tz (art ) Tj 0.898283 0 Td 54.703147 Tz (upon ) Tj 2.608476 0 Td 46.425697 Tz (mutation ) Tj 2.332082 0 Td 25.912017 Tz (/ ) Tj 0.138197 0 Td 50.384478 Tz (kb ) Tj 0.621888 0 Td 25.912017 Tz (, ) Tj 0.431867 0 Td 52.97568 Tz (which ) Tj 1.848391 0 Td 31.670243 Tz (is ) Tj 0.690987 0 Td 42.364092 Tz (similar ) Tj 2.003863 0 Td 40.307582 Tz (to ) Tj 0.777361 0 Td 43.762518 Tz (other ) Tj 1.554721 0 Td 41.95279 Tz (reports ) Tj 2.055687 0 Td 47.505365 Tz (of ) Tj 0.760086 0 Td 47.865254 Tz (mutation ) Tj 61.512605 0 0 61.512605 0 378.058318 Tm 5.234699 0 Td 45.609441 Tz (review ) Tj 1.885792 0 Td 46.06102 Tz (of ) Tj 0.715301 0 Td 40.642077 Tz (the ) Tj 0.97541 0 Td 40.913024 Tz (disclosure ) Tj 2.682377 0 Td 42.448391 Tz (herein ) Tj 1.755738 0 Td 47.867335 Tz (and ) Tj 1.072951 0 Td 41.545234 Tz (the ) Tj 0.97541 0 Td 47.996357 Tz (working ) Tj 2.259699 0 Td 47.077072 Tz (examples ) Tj 3.527732 0 Td 41.873655 Tz (frequencies ) Tj 2.92623 0 Td 37.932605 Tz (in ) Tj 0.585246 0 Td 44.555758 Tz (hexaploid ) Tj 2.519809 0 Td 44.977231 Tz (bread ) Tj 1.479372 0 Td 48.228597 Tz (wheat ) Tj 1.576913 0 Td 56.898907 Tz (TILLING ) Tj 2.503552 0 Td 42.612601 Tz (populations ) Tj 2.893716 0 Td 10.837887 Tz (. ) Tj 62.380952 0 0 62.380952 0 334.01043 Tm 5.161832 0 Td 48.625954 Tz (below ) Tj 1.474809 0 Td 10.687023 Tz (. ) Tj 0.320611 0 Td 28.053435 Tz (It ) Tj 0.545038 0 Td 37.40458 Tz (will ) Tj 1.122137 0 Td 46.755725 Tz (be ) Tj 0.785496 0 Td 41.533657 Tz (appreciated ) Tj 2.933588 0 Td 37.40458 Tz (that ) Tj 1.090076 0 Td 40.966921 Tz (the ) Tj 0.929771 0 Td 41.603053 Tz (various ) Tj 1.987786 0 Td 48.33449 Tz (embodiments ) Tj 4.440458 0 Td 56.10687 Tz (Two ) Tj 1.50687 0 Td 43.962526 Tz (independent ) Tj 3.350382 0 Td 49.872774 Tz (non ) Tj 0.929771 0 Td 24.045802 Tz (- ) Tj 0.208397 0 Td 41.679389 Tz (sense ) Tj 1.699237 0 Td 43.341815 Tz (mutations ) Tj 2.805344 0 Td 48.759542 Tz (were ) Tj 1.635115 0 Td 37.40458 Tz (identified ) Tj 61.428571 0 0 61.428571 0 293.251421 Tm 5.25814 0 Td 43.109388 Tz (described ) Tj 2.669767 0 Td 42.054264 Tz (herein ) Tj 1.872093 0 Td 39.793282 Tz (are ) Tj 1.074419 0 Td 43.410853 Tz (not ) Tj 1.123256 0 Td 40.944327 Tz (necessarily ) Tj 3.060465 0 Td 44.767442 Tz (mutually ) Tj 2.523256 0 Td 42.204996 Tz (exclusive ) Tj 3.532558 0 Td 54.263566 Tz (among ) Tj 1.806977 0 Td 40.697674 Tz (the ) Tj 0.927907 0 Td 40.358527 Tz (selected ) Tj 2.1 0 Td 47.028424 Tz (mutant ) Tj 1.855814 0 Td 38.888889 Tz (plants ) Tj 1.4 0 Td 27.131783 Tz (, ) Tj 0.374419 0 Td 48.837209 Tz (where ) Tj 1.644186 0 Td 46.937984 Tz (Tryptophan ) Tj 2.995349 0 Td 48.837209 Tz (amino ) Tj 67.142857 0 0 67.142857 0 249.98212 Tm 4.795745 0 Td 38.061466 Tz (unless ) Tj 1.638298 0 Td 39.716312 Tz (otherwise ) Tj 2.412766 0 Td 37.50985 Tz (indicated ) Tj 2.26383 0 Td 37.647754 Tz (herein ) Tj 1.385106 0 Td 17.375887 Tz (. ) Tj 0.387234 0 Td 43.026005 Tz (For ) Tj 1.012766 0 Td 43.971631 Tz (example ) Tj 1.831915 0 Td 24.822695 Tz (, ) Tj 0.431915 0 Td 37.234043 Tz (a ) Tj 0.476596 0 Td 36.524823 Tz (feature ) Tj 1.906383 0 Td 31.028369 Tz (65 ) Tj 0.774468 0 Td 36.737589 Tz (acids ) Tj 1.340426 0 Td 45.301418 Tz (were ) Tj 1.310638 0 Td 42.907801 Tz (mutated ) Tj 2.010638 0 Td 33.510638 Tz (to ) Tj 0.655319 0 Td 41.646966 Tz (premature ) Tj 2.502128 0 Td 35.992908 Tz (stop ) Tj 1.131915 0 Td 42.612293 Tz (codons ) Tj 1.787234 0 Td 32.269504 Tz (at ) Tj 0.610638 0 Td 36.958235 Tz (positions ) Tj 60 0 0 60 0 209.617139 Tm 5.383333 0 Td 44.135802 Tz (described ) Tj 2.733333 0 Td 43.055556 Tz (or ) Tj 0.866667 0 Td 43.75 Tz (depicted ) Tj 2.466667 0 Td 38.888889 Tz (in ) Tj 0.833333 0 Td 48.148148 Tz (one ) Tj 1.25 0 Td 51.388889 Tz (embodiment ) Tj 3.45 0 Td 58.333333 Tz (may ) Tj 1.433333 0 Td 39.583333 Tz (also ) Tj 1.333333 0 Td 48.611111 Tz (be ) Tj 1.866667 0 Td 48.148148 Tz (233 ) Tj 1.216667 0 Td 49.074074 Tz (and ) Tj 1.183333 0 Td 46.296296 Tz (361 ) Tj 1.216667 0 Td 38.888889 Tz (in ) Tj 0.75 0 Td 41.666667 Tz (the ) Tj 1.066667 0 Td 47.685185 Tz (second ) Tj 2 0 Td 41.944444 Tz (agglutinin ) Tj 2.816667 0 Td 51.388889 Tz (domain ) Tj 2.15 0 Td 49.074074 Tz (and ) Tj 1.183333 0 Td 65.740741 Tz (ETX ) Tj 1.2 0 Td 27.777778 Tz (/ ) Tj 58.907563 0 0 58.907563 0 170.192337 Tm 5.483167 0 Td 45.268664 Tz (included ) Tj 2.59729 0 Td 39.610081 Tz (in ) Tj 0.882739 0 Td 43.571089 Tz (other ) Tj 1.714551 0 Td 50.41283 Tz (embodiments ) Tj 3.39515 0 Td 25.463623 Tz (, ) Tj 0.577175 0 Td 44.325567 Tz (but ) Tj 1.222254 0 Td 31.122206 Tz (is ) Tj 0.814836 0 Td 44.325567 Tz (not ) Tj 1.205278 0 Td 42.696581 Tz (necessarily ) Tj 4.125107 0 Td 70.024964 Tz (MTX2 ) Tj 1.935235 0 Td 52.813441 Tz (domain ) Tj 2.104993 0 Td 41.496275 Tz (respectively ) Tj 2.970756 0 Td 28.292915 Tz (, ) Tj 0.441369 0 Td 48.097955 Tz (of ) Tj 0.729957 0 Td 42.439372 Tz (the ) Tj 0.984593 0 Td 40.014265 Tz (protein ) Tj 1.782454 0 Td 28.292915 Tz (. ) Tj 31.428571 0 0 31.428571 0 1300 Tm 39.518182 0 Td 74.242424 Tz (40 ) Tj 31.428571 0 0 31.428571 0 1007 Tm 36.368182 0 Td 102.083333 Tz (some ) Tj ET Q endstream endobj 193 0 obj << /Length 1 >> stream q endstream endobj 194 0 obj << /Length 52177 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 30 0 0 30 0 2757 Tm 41.666667 0 Td 61.111111 Tz (5 ) Tj 34.285714 0 0 34.285714 0 2545 Tm 36.283333 0 Td 65.625 Tz (10 ) Tj 31.428571 0 0 31.428571 0 1717 Tm 39.55 0 Td 71.590909 Tz (30 ) Tj 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 52.857143 0 0 52.857143 0 2973 Tm 14.132432 0 Td 72.522523 Tz (25 ) Tj 51.428571 0 0 51.428571 0 2973 Tm 33.463889 0 Td 74.537037 Tz (26 ) Tj 60.519481 0 0 60.519481 0 2914.055021 Tm 5.948498 0 Td 46.816881 Tz (Phenotyping ) Tj 3.370815 0 Td 46.816881 Tz (of ) Tj 0.743562 0 Td 41.309013 Tz (the ) Tj 1.00794 0 Td 50.488794 Tz (two ) Tj 1.1897 0 Td 46.030043 Tz (mutants ) Tj 2.230687 0 Td 44.613734 Tz (along ) Tj 1.60279 0 Td 46.128398 Tz (with ) Tj 1.387983 0 Td 46.816881 Tz (S ) Tj 0.346996 0 Td 24.785408 Tz (- ) Tj 0.165236 0 Td 55.996662 Tz (NIL ) Tj 1.272318 0 Td 49.570815 Tz (and ) Tj 57.142857 0 0 57.142857 0 2918.129252 Tm 29.12 0 Td 54.583333 Tz (Example ) Tj 2.5375 0 Td 46.666667 Tz (4 ) Tj 60 0 0 60 0 2872.5325 Tm 5.383333 0 Td 66.666667 Tz (R ) Tj 0.433333 0 Td 25 Tz (- ) Tj 0.183333 0 Td 56.481481 Tz (NIL ) Tj 1.166667 0 Td 40.972222 Tz (controls ) Tj 2.15 0 Td 52.777778 Tz (was ) Tj 1.133333 0 Td 49.305556 Tz (done ) Tj 1.366667 0 Td 38.888889 Tz (in ) Tj 0.616667 0 Td 41.666667 Tz (the ) Tj 0.933333 0 Td 46.666667 Tz (greenhouse ) Tj 2.983333 0 Td 45.061728 Tz (according ) Tj 2.583333 0 Td 38.888889 Tz (to ) Tj 0.65 0 Td 41.666667 Tz (the ) Tj 61.428571 0 0 61.428571 0 2831.968176 Tm 5.25814 0 Td 43.109388 Tz (described ) Tj 2.474419 0 Td 44.918174 Tz (procedure ) Tj 2.393023 0 Td 27.131783 Tz (. ) Tj 0.390698 0 Td 44.186047 Tz (Scoring ) Tj 2.034884 0 Td 47.932817 Tz (and ) Tj 1.025581 0 Td 46.370684 Tz (photography ) Tj 3.223256 0 Td 51.550388 Tz (was ) Tj 1.123256 0 Td 48.158915 Tz (done ) Tj 1.351163 0 Td 43.410853 Tz (21 ) Tj 47.142857 0 0 47.142857 0 2831 Tm 31.881818 0 Td 54.040404 Tz (Protein ) Tj 2.566667 0 Td 53.030303 Tz (Structure ) Tj 3.160606 0 Td 58.469308 Tz (Determination ) Tj 58.571429 0 0 58.571429 0 2791.77875 Tm 5.514634 0 Td 46.95122 Tz (days ) Tj 1.34878 0 Td 38.699187 Tz (after ) Tj 1.331707 0 Td 42.165558 Tz (inoculation ) Tj 2.902439 0 Td 19.918699 Tz (. ) Tj 0.307317 0 Td 44.105691 Tz (In ) Tj 0.682927 0 Td 47.662602 Tz (both ) Tj 1.314634 0 Td 42.682927 Tz (the ) Tj 0.973171 0 Td 46.821877 Tz (independent ) Tj 3.278049 0 Td 47.154472 Tz (mutants ) Tj 2.202439 0 Td 39.837398 Tz (loss ) Tj 57.89916 0 0 57.89916 0 2748.404184 Tm 5.578665 0 Td 48.935656 Tz (of ) Tj 0.880842 0 Td 42.314949 Tz (resistance ) Tj 2.918868 0 Td 49.895178 Tz (due ) Tj 1.278084 0 Td 38.860668 Tz (to ) Tj 0.846299 0 Td 48.295974 Tz (premature ) Tj 2.987954 0 Td 43.754233 Tz (truncation ) Tj 2.987954 0 Td 48.935656 Tz (of ) Tj 0.880842 0 Td 43.17852 Tz (the ) Tj 1.157184 0 Td 61.889211 Tz (FHB1 ) Tj 3.523367 0 Td 44.412192 Tz (Protein ) Tj 2.124383 0 Td 48.216014 Tz (sequence ) Tj 2.556168 0 Td 44.457883 Tz (predicted ) Tj 2.642525 0 Td 50.37494 Tz (from ) Tj 1.502612 0 Td 41.259474 Tz (the ) Tj 1.001742 0 Td 49.655298 Tz (gene ) Tj 1.46807 0 Td 48.216014 Tz (sequence ) Tj 2.556168 0 Td 54.692791 Tz (was ) Tj 60.612245 0 0 60.612245 0 2707.626346 Tm 5.312458 0 Td 41.638608 Tz (protein ) Tj 1.9633 0 Td 52.244669 Tz (was ) Tj 1.204377 0 Td 45.714085 Tz (observed ) Tj 2.210774 0 Td 24.747475 Tz (, ) Tj 0.362963 0 Td 45.566779 Tz (proving ) Tj 2.144781 0 Td 50.411523 Tz (beyond ) Tj 2.045791 0 Td 46.195286 Tz (doubt ) Tj 1.600337 0 Td 38.496072 Tz (that ) Tj 1.154882 0 Td 41.245791 Tz (the ) Tj 0.989899 0 Td 47.43266 Tz (gene ) Tj 2.392256 0 Td 47.43266 Tz (used ) Tj 1.286869 0 Td 37.121212 Tz (to ) Tj 0.643434 0 Td 45.217608 Tz (determine ) Tj 2.606734 0 Td 41.245791 Tz (the ) Tj 0.923906 0 Td 59.118967 Tz (3D ) Tj 0.923906 0 Td 39.107121 Tz (structure ) Tj 2.293266 0 Td 45.37037 Tz (of ) Tj 0.643434 0 Td 41.245791 Tz (the ) Tj 0.923906 0 Td 47.43266 Tz (gene ) Tj 1.303367 0 Td 43.995511 Tz (using ) Tj 1.501347 0 Td 42.031425 Tz (Protein ) Tj 56.122449 0 0 56.122449 0 2670.580822 Tm 5.755273 0 Td 49 Tz (cloned ) Tj 1.995636 0 Td 43.060606 Tz (in ) Tj 0.730545 0 Td 38.606061 Tz (this ) Tj 1.211636 0 Td 46.921212 Tz (study ) Tj 1.657091 0 Td 32.666667 Tz (is ) Tj 0.659273 0 Td 57.166667 Tz (Fhb1 ) Tj 1.389818 0 Td 20.787879 Tz (. ) Tj 57.792208 0 0 57.792208 0 2671.711276 Tm 22.442472 0 Td 63.445693 Tz (Homology ) Tj 3.08 0 Td 11.535581 Tz (/ ) Tj 0.138427 0 Td 41.198502 Tz (analogy ) Tj 1.937978 0 Td 47.715356 Tz (Recognition ) Tj 3.322247 0 Td 49.987516 Tz (Engine ) Tj 1.972584 0 Td 74.981273 Tz (V ) Tj 0.744045 0 Td 33.645443 Tz (2.0 ) Tj 0.899775 0 Td 34.606742 Tz (\( ) Tj 0.242247 0 Td 69.213483 Tz (PHYRE ) Tj 2.232135 0 Td 42.297129 Tz (2.0 ) Tj 0.830562 0 Td 11.535581 Tz (, ) Tj 56 0 0 56 0 2635.038511 Tm 23.142857 0 Td 45.955882 Tz (http://www.sbg.bio.ic.ac.uk/phyre2 ) Tj 9.464286 0 Td 35.714286 Tz (\) ) Tj 0.107143 0 Td 35.714286 Tz (. ) Tj 1.303571 0 Td 49.107143 Tz (Software ) Tj 3.392857 0 Td 72.916667 Tz (JMOL ) Tj 56.428571 0 0 56.428571 0 2597.538462 Tm 12.210127 0 Td 55.696203 Tz (Example ) Tj 2.622785 0 Td 32.489451 Tz (1 ) Tj 65.714286 0 0 65.714286 0 2588.945978 Tm 19.752174 0 Td 30.434783 Tz (\( ) Tj 0.167391 0 Td 37.318841 Tz (http://jmol.sourceforge.net/ ) Tj 6.193478 0 Td 30.434783 Tz (\) ) Tj 0.365217 0 Td 47.342995 Tz (was ) Tj 1.034783 0 Td 43.115942 Tz (used ) Tj 1.186957 0 Td 34.23913 Tz (to ) Tj 0.593478 0 Td 45.652174 Tz (view ) Tj 1.263043 0 Td 38.043478 Tz (the ) Tj 0.867391 0 Td 36.352657 Tz (structure ) Tj 55.357143 0 0 55.357143 0 2554.529101 Tm 23.411613 0 Td 54.193548 Tz (of ) Tj 0.812903 0 Td 45.16129 Tz (the ) Tj 1.065806 0 Td 42.150538 Tz (protein ) Tj 1.842581 0 Td 30.107527 Tz (. ) Tj 56.571429 0 0 56.571429 0 2504.911565 Tm 9.244949 0 Td 44.191919 Tz (Plant ) Tj 1.573232 0 Td 45.501309 Tz (Materials ) Tj 2.722222 0 Td 52.04826 Tz (and ) Tj 1.166667 0 Td 68.742985 Tz (FHB ) Tj 1.467172 0 Td 51.066218 Tz (Assays ) Tj 55.714286 0 0 55.714286 0 2481.416667 Tm 29.848718 0 Td 55.555556 Tz (Example ) Tj 2.620513 0 Td 41.880342 Tz (5 ) Tj 57.142857 0 0 57.142857 0 2416.986945 Tm 6.3175 0 Td 43.75 Tz (Resistant ) Tj 2.59 0 Td 51.527778 Tz (and ) Tj 1.155 0 Td 43.484848 Tz (susceptible ) Tj 3.08 0 Td 47.395833 Tz (near ) Tj 1.33 0 Td 44.479167 Tz (isogenic ) Tj 2.38 0 Td 39.666667 Tz (lines ) Tj 1.4525 0 Td 29.166667 Tz (\( ) Tj 0.21 0 Td 70 Tz (R ) Tj 0.455 0 Td 26.25 Tz (- ) Tj 0.175 0 Td 60.277778 Tz (NIL ) Tj 1.2775 0 Td 52.5 Tz (and ) Tj 48.571429 0 0 48.571429 0 2395 Tm 31.108824 0 Td 52.843137 Tz (Validation ) Tj 3.458824 0 Td 56.617647 Tz (of ) Tj 0.864706 0 Td 51.470588 Tz (the ) Tj 1.214706 0 Td 61.764706 Tz (Cloned ) Tj 2.491176 0 Td 66.053922 Tz (Gene ) Tj 61.428571 0 0 61.428571 0 2375.146163 Tm 5.274419 0 Td 46.124031 Tz (S ) Tj 0.34186 0 Td 24.418605 Tz (- ) Tj 0.162791 0 Td 56.072351 Tz (NIL ) Tj 1.04186 0 Td 27.131783 Tz (\) ) Tj 0.309302 0 Td 48.837209 Tz (were ) Tj 1.318605 0 Td 46.802326 Tz (used ) Tj 1.269767 0 Td 38.888889 Tz (for ) Tj 0.846512 0 Td 43.139535 Tz (expression ) Tj 2.718605 0 Td 38.587425 Tz (profiling ) Tj 2.262791 0 Td 39.147287 Tz (studies ) Tj 1.660465 0 Td 18.992248 Tz (. ) Tj 0.276744 0 Td 48.837209 Tz (Fusarium ) Tj 56.285714 0 0 56.285714 0 2336.452659 Tm 5.685279 0 Td 54.645439 Tz (graminearum ) Tj 4.015228 0 Td 39.974619 Tz (strain ) Tj 1.794416 0 Td 58.629442 Tz (K3639 ) Tj 2.13198 0 Td 56.260575 Tz (was ) Tj 1.385787 0 Td 50.338409 Tz (used ) Tj 1.563452 0 Td 42.442188 Tz (for ) Tj 1.119289 0 Td 43.608676 Tz (inoculation ) Tj 2.984772 0 Td 23.688663 Tz (. ) Tj 0.479695 0 Td 38.494078 Tz (F. ) Tj 0.959391 0 Td 35.532995 Tz (15 ) Tj 57.922078 0 0 57.922078 0 2294.4 Tm 5.524664 0 Td 53.101644 Tz (graminearum ) Tj 3.780942 0 Td 54.671151 Tz (was ) Tj 1.260314 0 Td 43.880792 Tz (cultured ) Tj 2.365247 0 Td 53.232436 Tz (on ) Tj 0.880493 0 Td 60.426009 Tz (mung ) Tj 1.709193 0 Td 51.074365 Tz (bean ) Tj 1.467489 0 Td 45.463378 Tz (broth ) Tj 1.62287 0 Td 37.406577 Tz (at ) Tj 0.707848 0 Td 48.916293 Tz (25 ) Tj 0.673318 0 Td 31.651719 Tz ( ) Tj 0.483408 0 Td 44.600149 Tz (C. ) Tj 57.142857 0 0 57.142857 0 2307.44801 Tm 23.345 0 Td 45.694444 Tz (Targeting ) Tj 2.695 0 Td 50 Tz (Induced ) Tj 2.31 0 Td 48.416667 Tz (Local ) Tj 1.68 0 Td 47.5 Tz (Lesions ) Tj 2.24 0 Td 42.291667 Tz (in ) Tj 0.7175 0 Td 60.763889 Tz (Genome ) Tj 2.4325 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 61.25 Tz (TILLING ) Tj 2.59 0 Td 29.166667 Tz (\) ) Tj 65.714286 0 0 65.714286 0 2253.298701 Tm 4.930435 0 Td 43.115942 Tz (shaken ) Tj 1.704348 0 Td 32.971014 Tz (at ) Tj 0.593478 0 Td 43.961353 Tz (100 ) Tj 0.928261 0 Td 42.270531 Tz (rpm ) Tj 0.958696 0 Td 17.753623 Tz (. ) Tj 0.213043 0 Td 46.92029 Tz (At ) Tj 0.730435 0 Td 38.677536 Tz (anthesis ) Tj 1.780435 0 Td 22.826087 Tz (, ) Tj 0.380435 0 Td 34.23913 Tz (10th ) Tj 1.019565 0 Td 36.141304 Tz (spikelet ) Tj 1.886957 0 Td 43.115942 Tz (of ) Tj 0.608696 0 Td 38.043478 Tz (the ) Tj 0.852174 0 Td 38.043478 Tz (spikes ) Tj 1.536957 0 Td 35.507246 Tz (to ) Tj 58.571429 0 0 58.571429 0 2269.47319 Tm 22.143902 0 Td 48.373984 Tz (approach ) Tj 2.595122 0 Td 54.065041 Tz (was ) Tj 1.263415 0 Td 49.085366 Tz (used ) Tj 1.434146 0 Td 39.837398 Tz (to ) Tj 0.768293 0 Td 41.971545 Tz (validate ) Tj 2.304878 0 Td 42.682927 Tz (the ) Tj 1.058537 0 Td 46.95122 Tz (cloned ) Tj 1.980488 0 Td 49.085366 Tz (gene ) Tj 1.195122 0 Td 19.918699 Tz (. ) Tj 0.460976 0 Td 47.804878 Tz (Seeds ) Tj 1.741463 0 Td 48.373984 Tz (of ) Tj 58.412698 0 0 58.412698 0 2213.709838 Tm 5.5125 0 Td 49.932065 Tz (be ) Tj 0.7875 0 Td 41.847826 Tz (tested ) Tj 1.677717 0 Td 51.358696 Tz (were ) Tj 1.455163 0 Td 44.225543 Tz (inoculated ) Tj 2.824728 0 Td 47.79212 Tz (with ) Tj 1.386685 0 Td 47.078804 Tz (10 ) Tj 0.77038 0 Td 38.519022 Tz (ul ) Tj 0.667663 0 Td 46.749582 Tz (macroconidial ) Tj 3.903261 0 Td 53.736413 Tz (suspen ) Tj 57.142857 0 0 57.142857 0 2228.746114 Tm 22.6975 0 Td 70 Tz (R ) Tj 0.455 0 Td 26.25 Tz (- ) Tj 0.175 0 Td 60.277778 Tz (NIL ) Tj 1.3825 0 Td 53.229167 Tz (were ) Tj 1.5925 0 Td 42.5 Tz (treated ) Tj 2.1 0 Td 48.854167 Tz (with ) Tj 1.505 0 Td 42 Tz (ethyl ) Tj 1.61 0 Td 47.942708 Tz (methanesulfonate ) Tj 4.97 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 72.916667 Tz (EMS ) Tj 1.3475 0 Td 29.166667 Tz (\) ) Tj 0.245 0 Td 14.583333 Tz (, ) Tj 52.857143 0 0 52.857143 0 2176 Tm 6.12973 0 Td 48.085586 Tz (sion ) Tj 1.381081 0 Td 39.414414 Tz (at ) Tj 0.718919 0 Td 47.297297 Tz (a ) Tj 0.52973 0 Td 49.237699 Tz (concentration ) Tj 4.048649 0 Td 53.603604 Tz (of ) Tj 0.87027 0 Td 52.027027 Tz (10 ) Tj 0.643243 0 Td 34.684685 Tz (% ) Tj 0.472973 0 Td 52.28979 Tz (macroconidia ) Tj 3.916216 0 Td 22.072072 Tz (/ ) Tj 0.037838 0 Td 78.828829 Tz (ml ) Tj 0.87027 0 Td 22.072072 Tz (. ) Tj 0.359459 0 Td 59.90991 Tz (The ) Tj 1.381081 0 Td 57.387387 Tz (inocu ) Tj 58.571429 0 0 58.571429 0 2193.061842 Tm 22.126829 0 Td 52.357724 Tz (which ) Tj 1.895122 0 Td 31.300813 Tz (is ) Tj 0.734146 0 Td 42.682927 Tz (a ) Tj 0.597561 0 Td 47.306911 Tz (chemical ) Tj 2.612195 0 Td 52.439024 Tz (mutagen ) Tj 2.509756 0 Td 47.899729 Tz (mostly ) Tj 2.065854 0 Td 45.934959 Tz (causing ) Tj 2.253659 0 Td 40.096083 Tz (transitions ) Tj 79.545455 0 0 79.545455 0 2116.208457 Tm 4.048 0 Td 30.590476 Tz (lated ) Tj 1.106286 0 Td 32.126984 Tz (spikes ) Tj 1.332571 0 Td 38.238095 Tz (were ) Tj 1.106286 0 Td 35.918367 Tz (covered ) Tj 1.546286 0 Td 39.809524 Tz (with ) Tj 1.131429 0 Td 34.047619 Tz (moisture ) Tj 1.684571 0 Td 33.52381 Tz (- ) Tj 0.150857 0 Td 30.962963 Tz (saturated ) Tj 1.722286 0 Td 36.217687 Tz (ziplock ) Tj 1.810286 0 Td 28.285714 Tz (20 ) Tj 0.666286 0 Td 48.190476 Tz (M1 ) Tj 0.88 0 Td 30.730159 Tz (plants ) Tj 1.081143 0 Td 35.619048 Tz (, ) Tj 0.276571 0 Td 39.809524 Tz (which ) Tj 1.370286 0 Td 41.904762 Tz (were ) Tj 1.093714 0 Td 35.619048 Tz (allowed ) Tj 1.672 0 Td 30.380952 Tz (to ) Tj 0.528 0 Td 31.952381 Tz (self ) Tj 0.741714 0 Td 35.619048 Tz (- ) Tj 0.226286 0 Td 29.333333 Tz (pollinate ) Tj 1.546286 0 Td 35.619048 Tz (, ) Tj 0.314286 0 Td 32.214286 Tz (yielding ) Tj 57.142857 0 0 57.142857 0 2151.698734 Tm 22.715 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 75.833333 Tz (G ) Tj 0.4725 0 Td 58.333333 Tz (> ) Tj 0.3675 0 Td 78.75 Tz (A ) Tj 0.595 0 Td 52.5 Tz (and ) Tj 1.1025 0 Td 67.083333 Tz (C ) Tj 0.4375 0 Td 58.333333 Tz (> ) Tj 0.3675 0 Td 61.25 Tz (T ) Tj 0.525 0 Td 48.611111 Tz (mutations ) Tj 2.6075 0 Td 29.166667 Tz (\) ) Tj 0.3675 0 Td 40.833333 Tz (in ) Tj 0.665 0 Td 75.833333 Tz (DNA ) Tj 1.4 0 Td 20.416667 Tz (. ) Tj 0.315 0 Td 51.333333 Tz (These ) Tj 1.7325 0 Td 45.5 Tz (seeds ) Tj 1.5575 0 Td 50.3125 Tz (gave ) Tj 1.365 0 Td 39.375 Tz (rise ) Tj 1.1025 0 Td 39.375 Tz (to ) Tj 60 0 0 60 0 2088.843357 Tm 5.366667 0 Td 46.527778 Tz (bags ) Tj 1.533333 0 Td 39.814815 Tz (for ) Tj 1.083333 0 Td 48.611111 Tz (72 ) Tj 0.983333 0 Td 46.111111 Tz (hours ) Tj 1.4 0 Td 19.444444 Tz (. ) Tj 0.516667 0 Td 48.148148 Tz (For ) Tj 1.233333 0 Td 72.222222 Tz (RNA ) Tj 1.65 0 Td 41.388889 Tz (extraction ) Tj 2.85 0 Td 41.666667 Tz (the ) Tj 1.133333 0 Td 43.333333 Tz (inoculated ) Tj 61.428571 0 0 61.428571 0 2071.7866 Tm 21.113953 0 Td 66.472868 Tz (M2 ) Tj 1.04186 0 Td 42.868217 Tz (seeds ) Tj 1.204651 0 Td 32.55814 Tz (. ) Tj 0.374419 0 Td 73.255814 Tz (A ) Tj 0.586047 0 Td 56.589147 Tz (TILLING ) Tj 2.555814 0 Td 43.410853 Tz (population ) Tj 2.8 0 Td 46.124031 Tz (of ) Tj 0.732558 0 Td 42.325581 Tz (1,932 ) Tj 1.497674 0 Td 40.451022 Tz (individuals ) Tj 2.865116 0 Td 51.550388 Tz (was ) Tj 60 0 0 60 0 2051.815217 Tm 5.4 0 Td 39.583333 Tz (spikelet ) Tj 2.066667 0 Td 49.074074 Tz (and ) Tj 1.033333 0 Td 43.055556 Tz (adjacent ) Tj 2.233333 0 Td 39.506173 Tz (spikelets ) Tj 2.3 0 Td 50 Tz (were ) Tj 1.35 0 Td 44.135802 Tz (harvested ) Tj 2.55 0 Td 34.722222 Tz (at ) Tj 0.583333 0 Td 42.676768 Tz (appropriate ) Tj 60.595238 0 0 60.595238 0 2040.750308 Tm 21.371316 0 Td 47.06396 Tz (developed ) Tj 2.673477 0 Td 49.508841 Tz (by ) Tj 0.792141 0 Td 48.722986 Tz (growing ) Tj 2.178389 0 Td 49.508841 Tz (one ) Tj 1.039686 0 Td 85.265226 Tz (M2 ) Tj 1.00668 0 Td 45.383104 Tz (seed ) Tj 1.254224 0 Td 42.174198 Tz (per ) Tj 0.924165 0 Td 63.261297 Tz (M1 ) Tj 0.990177 0 Td 42.357564 Tz (plant ) Tj 1.204715 0 Td 27.504912 Tz (. ) Tj 0.313556 0 Td 53.176162 Tz (The ) Tj 1.1222 0 Td 73.346431 Tz (DNA ) Tj 57.619048 0 0 57.619048 0 2008.509138 Tm 5.605785 0 Td 40.495868 Tz (intervals ) Tj 2.516529 0 Td 39.338843 Tz (after ) Tj 1.475207 0 Td 44.352617 Tz (inoculations ) Tj 3.158678 0 Td 20.247934 Tz (. ) Tj 0.468595 0 Td 47.107438 Tz (Disease ) Tj 2.308264 0 Td 44.628099 Tz (scoring ) Tj 2.169421 0 Td 53.99449 Tz (was ) Tj 1.301653 0 Td 51.342975 Tz (done ) Tj 1.544628 0 Td 46.280992 Tz (21 ) Tj 60 0 0 60 0 1997.174419 Tm 21.616667 0 Td 47.222222 Tz (of ) Tj 0.733333 0 Td 32.407407 Tz (all ) Tj 0.816667 0 Td 41.666667 Tz (the ) Tj 0.983333 0 Td 69.444444 Tz (M2 ) Tj 1.083333 0 Td 41.414141 Tz (individuals ) Tj 2.966667 0 Td 52.777778 Tz (was ) Tj 1.2 0 Td 42.283951 Tz (extracted ) Tj 2.483333 0 Td 44.444444 Tz (using ) Tj 1.583333 0 Td 49.537037 Tz (Qiagen ) Tj 2.05 0 Td 60.185185 Tz (Bio ) Tj 54.642857 0 0 54.642857 0 1971.265432 Tm 5.89281 0 Td 50.326797 Tz (days ) Tj 1.482353 0 Td 41.481481 Tz (after ) Tj 1.518954 0 Td 46.259985 Tz (inoculations ) Tj 3.330719 0 Td 24.400871 Tz (. ) Tj 55.714286 0 0 55.714286 0 1959.897436 Tm 23.297436 0 Td 41.381766 Tz (sprint ) Tj 1.794872 0 Td 79.77208 Tz (DNA ) Tj 1.687179 0 Td 44.57265 Tz (extraction ) Tj 2.979487 0 Td 50.854701 Tz (system ) Tj 1.884615 0 Td 11.965812 Tz (. ) Tj 0.394872 0 Td 56.837607 Tz (The ) Tj 1.328205 0 Td 79.77208 Tz (DNA ) Tj 1.669231 0 Td 56.837607 Tz (was ) Tj 1.328205 0 Td 50.25641 Tz (normalized ) Tj 55.714286 0 0 55.714286 0 1921.167598 Tm 22.328205 0 Td 38.888889 Tz (25 ) Tj 0.951282 0 Td 52.849003 Tz (and ) Tj 1.346154 0 Td 55.34188 Tz (4x ) Tj 1.076923 0 Td 48.717949 Tz (pooling ) Tj 2.441026 0 Td 55.840456 Tz (was ) Tj 1.435897 0 Td 53.846154 Tz (done ) Tj 1.292308 0 Td 20.940171 Tz (. ) Tj 0.574359 0 Td 62.07265 Tz (PCRs ) Tj 1.902564 0 Td 53.846154 Tz (were ) Tj 1.705128 0 Td 53.098291 Tz (done ) Tj 1.669231 0 Td 47.863248 Tz (using ) Tj 1.830769 0 Td 44.871795 Tz (the ) Tj 52.142857 0 0 52.142857 0 1900.222222 Tm 13.213699 0 Td 59.360731 Tz (Example ) Tj 2.8 0 Td 44.748858 Tz (2 ) Tj 64.897959 0 0 64.897959 0 1886.05483 Tm 19.969811 0 Td 41.375495 Tz (following ) Tj 2.634906 0 Td 43.658281 Tz (gene ) Tj 1.325157 0 Td 35.632862 Tz (specific ) Tj 2.049371 0 Td 41.457023 Tz (primers ) Tj 2.095597 0 Td 42.695231 Tz (spanning ) Tj 2.372956 0 Td 38.522013 Tz (the ) Tj 1.016981 0 Td 43.087584 Tz (conserved ) Tj 61.428571 0 0 61.428571 0 1843.22006 Tm 21.113953 0 Td 50.193798 Tz (domain ) Tj 2.262791 0 Td 44.767442 Tz (of ) Tj 0.911628 0 Td 40.697674 Tz (the ) Tj 1.204651 0 Td 46.802326 Tz (gene ) Tj 1.172093 0 Td 10.852713 Tz (: ) Tj 0.569767 0 Td 48.158915 Tz (Fhbl ) Tj 1.676744 0 Td 46.802326 Tz (gene ) Tj 1.595349 0 Td 45.348837 Tz (forward ) Tj 2.327907 0 Td 45.671835 Tz (primer ) Tj 2.1 0 Td 35.271318 Tz (\( ) Tj 0.195349 0 Td 47.48062 Tz (5' ) Tj 56.571429 0 0 56.571429 0 1804.407097 Tm 6.628788 0 Td 57.449495 Tz (Gene ) Tj 1.573232 0 Td 49.494949 Tz (Annotation ) Tj 3.199495 0 Td 53.030303 Tz (and ) Tj 1.184343 0 Td 56.712963 Tz (Gene ) Tj 1.626263 0 Td 44.191919 Tz (Structure ) Tj 2.633838 0 Td 48.724424 Tz (Determination ) Tj 6.063131 0 Td 73.211279 Tz (ATGGCACACGCTACATTGCT ) Tj 8.838384 0 Td 26.515152 Tz (- ) Tj 0.212121 0 Td 26.515152 Tz (3 ) Tj 0.141414 0 Td 26.515152 Tz (' ) Tj 0.353535 0 Td 29.461279 Tz (\( ) Tj 0.229798 0 Td 65.796857 Tz (SEQ ) Tj 1.361111 0 Td 54.503367 Tz (ID ) Tj 0.813131 0 Td 79.545455 Tz (NO ) Tj 1.007576 0 Td 11.784512 Tz (: ) Tj 0.212121 0 Td 45.664983 Tz (14 ) Tj 0.60101 0 Td 29.461279 Tz (\) ) Tj 0.229798 0 Td 29.461279 Tz (\) ) Tj 0.247475 0 Td 14.73064 Tz (; ) Tj 0.282828 0 Td 52.293771 Tz (Fhbl ) Tj 59.87013 0 0 59.87013 0 1765.456907 Tm 21.646855 0 Td 48.020607 Tz (gene ) Tj 1.319523 0 Td 42.552422 Tz (reverse ) Tj 1.95423 0 Td 46.396722 Tz (primer ) Tj 1.870716 0 Td 30.621837 Tz (\( ) Tj 0.233839 0 Td 30.621837 Tz (5 ) Tj 0.283948 0 Td 30.621837 Tz (' ) Tj 0.133623 0 Td 30.621837 Tz (- ) Tj 0.167028 0 Td 68.759942 Tz (CAACTTCGCCGTCAACTACA ) Tj 8.434924 0 Td 30.621837 Tz (- ) Tj 0.283948 0 Td 30.621837 Tz (3 ) Tj 0.100217 0 Td 30.621837 Tz (' ) Tj 60 0 0 60 0 1714.133676 Tm 6 0 Td 75 Tz (A ) Tj 0.616667 0 Td 41.049383 Tz (Bacterial ) Tj 2.4 0 Td 37.222222 Tz (Artificial ) Tj 2.466667 0 Td 55.555556 Tz (Chromosome ) Tj 3.583333 0 Td 27.777778 Tz (\( ) Tj 0.183333 0 Td 69.444444 Tz (BAC ) Tj 1.283333 0 Td 27.777778 Tz (\) ) Tj 0.4 0 Td 38.888889 Tz (library ) Tj 1.866667 0 Td 50.555556 Tz (devel ) Tj 64.285714 0 0 64.285714 0 1723.125 Tm 20.191111 0 Td 31.111111 Tz (\( ) Tj 0.217778 0 Td 57.037037 Tz (SEQ ) Tj 1.151111 0 Td 55.740741 Tz (ID ) Tj 0.917778 0 Td 63.518519 Tz (NO ) Tj 0.84 0 Td 33.703704 Tz (: ) Tj 0.28 0 Td 32.407407 Tz (15 ) Tj 0.482222 0 Td 33.703704 Tz (\) ) Tj 0.217778 0 Td 33.703704 Tz (\) ) Tj 0.14 0 Td 33.703704 Tz (. ) Tj 0.264444 0 Td 75.185185 Tz (A ) Tj 0.575556 0 Td 47.81893 Tz (touchdown ) Tj 2.784444 0 Td 36.296296 Tz (profile ) Tj 1.757778 0 Td 33.703704 Tz (\( ) Tj 0.202222 0 Td 42.777778 Tz (95 ) Tj 0.575556 0 Td 33.703704 Tz ( ) Tj 0.357778 0 Td 40.185185 Tz (C. ) Tj 0.544444 0 Td 23.333333 Tz (- ) Tj 0.202222 0 Td 36.296296 Tz (5 ) Tj 0.435556 0 Td 44.074074 Tz (minutes ) Tj 1.788889 0 Td 31.111111 Tz (, ) Tj 55.714286 0 0 55.714286 0 1674.790123 Tm 5.797436 0 Td 53.846154 Tz (oped ) Tj 1.579487 0 Td 53.846154 Tz (from ) Tj 1.597436 0 Td 55.641026 Tz (Sumai ) Tj 1.974359 0 Td 44.871795 Tz (3 ) Tj 0.610256 0 Td 55.840456 Tz (was ) Tj 1.310256 0 Td 51.602564 Tz (used ) Tj 1.507692 0 Td 41.880342 Tz (to ) Tj 0.84359 0 Td 46.866097 Tz (search ) Tj 1.974359 0 Td 42.877493 Tz (for ) Tj 1.041026 0 Td 44.871795 Tz (the ) Tj 1.112821 0 Td 47.198481 Tz (candidate ) Tj 57.142857 0 0 57.142857 0 1690.069837 Tm 22.715 0 Td 43.75 Tz (6 ) Tj 0.6125 0 Td 43.75 Tz (cycles ) Tj 1.925 0 Td 49.583333 Tz (of ) Tj 0.9275 0 Td 43.75 Tz (95 ) Tj 0.5775 0 Td 35 Tz ( ) Tj 0.49 0 Td 58.333333 Tz (C. ) Tj 0.7175 0 Td 26.25 Tz (- ) Tj 0.2275 0 Td 26.25 Tz (1 ) Tj 0.5425 0 Td 49.097222 Tz (minute ) Tj 1.8025 0 Td 26.25 Tz (, ) Tj 0.5075 0 Td 45.5 Tz (58-56 ) Tj 1.5575 0 Td 26.25 Tz ( ) Tj 0.5075 0 Td 46.666667 Tz (C. ) Tj 0.6125 0 Td 26.25 Tz (- ) Tj 0.2625 0 Td 29.166667 Tz (1 ) Tj 0.5425 0 Td 50.555556 Tz (minute ) Tj 2.1175 0 Td 48.854167 Tz (with ) Tj 1.47 0 Td 43.75 Tz (a ) Tj 58.142857 0 0 58.142857 0 1634.969657 Tm 5.538084 0 Td 49.447174 Tz (gene ) Tj 1.22113 0 Td 20.06552 Tz (. ) Tj 0.412776 0 Td 53.508054 Tz (The ) Tj 1.255528 0 Td 70.707071 Tz (BAC ) Tj 1.599509 0 Td 45.045045 Tz (Library ) Tj 2.167076 0 Td 54.463554 Tz (was ) Tj 1.307125 0 Td 45.864046 Tz (screened ) Tj 2.476658 0 Td 48.013923 Tz (with ) Tj 1.410319 0 Td 48.730549 Tz (markers ) Tj 2.356265 0 Td 50.880426 Tz (from ) Tj 60 0 0 60 0 1648.553425 Tm 21.616667 0 Td 44.097222 Tz (decrease ) Tj 2.35 0 Td 45.833333 Tz (of ) Tj 0.716667 0 Td 40.277778 Tz (0.5 ) Tj 1.216667 0 Td 43.055556 Tz (C. ) Tj 0.766667 0 Td 44.444444 Tz (per ) Tj 1 0 Td 43.333333 Tz (cycle ) Tj 1.333333 0 Td 13.888889 Tz (, ) Tj 0.333333 0 Td 48.611111 Tz (72 ) Tj 0.65 0 Td 30.555556 Tz ( ) Tj 0.433333 0 Td 43.055556 Tz (C. ) Tj 0.583333 0 Td 25 Tz (- ) Tj 0.25 0 Td 27.777778 Tz (1 ) Tj 0.433333 0 Td 47.685185 Tz (minute ) Tj 2 0 Td 43.055556 Tz (15 ) Tj 0.783333 0 Td 45.634921 Tz (seconds ) Tj 1.983333 0 Td 13.888889 Tz (, ) Tj 57.142857 0 0 57.142857 0 1593.10285 Tm 5.6525 0 Td 49.583333 Tz (Chinese ) Tj 2.3275 0 Td 47.152778 Tz (Spring ) Tj 1.925 0 Td 51.770833 Tz (Fhbl ) Tj 1.505 0 Td 46.666667 Tz (region ) Tj 1.8725 0 Td 40.833333 Tz (to ) Tj 0.7175 0 Td 43.425926 Tz (delineate ) Tj 2.5375 0 Td 43.75 Tz (putative ) Tj 2.3275 0 Td 46.018519 Tz (candidate ) Tj 57.142857 0 0 57.142857 0 1609.387534 Tm 22.6975 0 Td 48.125 Tz (followed ) Tj 2.485 0 Td 53.958333 Tz (by ) Tj 0.8575 0 Td 52.5 Tz (30 ) Tj 0.84 0 Td 44.236111 Tz (cycles ) Tj 1.82 0 Td 48.125 Tz (of ) Tj 0.735 0 Td 48.125 Tz (95 ) Tj 0.665 0 Td 32.083333 Tz ( ) Tj 0.42 0 Td 45.208333 Tz (C. ) Tj 0.6125 0 Td 26.25 Tz (- ) Tj 0.2625 0 Td 29.166667 Tz (1 ) Tj 0.4375 0 Td 49.583333 Tz (minute ) Tj 1.785 0 Td 26.25 Tz (, ) Tj 0.4025 0 Td 49.583333 Tz (54 ) Tj 0.665 0 Td 32.083333 Tz ( ) Tj 0.42 0 Td 45.208333 Tz (C. ) Tj 0.6125 0 Td 26.25 Tz (- ) Tj 0.2625 0 Td 29.166667 Tz (1 ) Tj 0.4375 0 Td 48.611111 Tz (minute ) Tj 1.785 0 Td 26.25 Tz (, ) Tj 52.857143 0 0 52.857143 0 1574 Tm 24.537838 0 Td 55.18018 Tz (72 ) Tj 0.718919 0 Td 34.684685 Tz ( ) Tj 0.548649 0 Td 48.873874 Tz (C. ) Tj 0.662162 0 Td 28.378378 Tz (- ) Tj 0.283784 0 Td 31.531532 Tz (1 ) Tj 0.548649 0 Td 54.654655 Tz (minute ) Tj 2.327027 0 Td 48.873874 Tz (15 ) Tj 0.945946 0 Td 51.801802 Tz (seconds ) Tj 2.232432 0 Td 15.765766 Tz (, ) Tj 0.435135 0 Td 56.756757 Tz (and ) Tj 1.305405 0 Td 47.297297 Tz (a ) Tj 0.586486 0 Td 40.990991 Tz (final ) Tj 1.551351 0 Td 49.74975 Tz (extension ) Tj 2.989189 0 Td 53.603604 Tz (of ) Tj 0.87027 0 Td 53.603604 Tz (72 ) Tj 0.718919 0 Td 34.684685 Tz ( ) Tj 58.571429 0 0 58.571429 0 1551.487242 Tm 5.514634 0 Td 47.662602 Tz (gene ) Tj 1.195122 0 Td 19.918699 Tz (. ) Tj 0.32439 0 Td 54.776423 Tz (Gene ) Tj 1.485366 0 Td 44.674797 Tz (annotation ) Tj 2.85122 0 Td 50.271003 Tz (and ) Tj 1.058537 0 Td 49.085366 Tz (gene ) Tj 1.365854 0 Td 40.785908 Tz (structure ) Tj 2.373171 0 Td 45.309568 Tz (determination ) Tj 3.670732 0 Td 54.065041 Tz (was ) Tj 71.176471 0 0 71.176471 0 1499.426918 Tm 4.509917 0 Td 42.14876 Tz (done ) Tj 1.222314 0 Td 37.933884 Tz (using ) Tj 1.320661 0 Td 56.198347 Tz (FGENESH ) Tj 2.542975 0 Td 43.709826 Tz (and ) Tj 0.955372 0 Td 53.466483 Tz (BLASTx ) Tj 2.135537 0 Td 37.465565 Tz (searches ) Tj 1.71405 0 Td 32.782369 Tz (. ) Tj 0.33719 0 Td 52.68595 Tz (NCBI ) Tj 1.36281 0 Td 42.73416 Tz (con- ) Tj 1.37686 0 Td 31.61157 Tz (35 ) Tj 0.716529 0 Td 38.506275 Tz (denatured ) Tj 2.332231 0 Td 42.14876 Tz (and ) Tj 1.02562 0 Td 38.246097 Tz (slowly ) Tj 1.657851 0 Td 36.763085 Tz (reannealed ) Tj 2.486777 0 Td 38.636364 Tz (to ) Tj 0.67438 0 Td 43.319559 Tz (form ) Tj 1.264463 0 Td 38.803621 Tz (heteroduplexes ) Tj 56.309524 0 0 56.309524 0 1535.791938 Tm 23.033404 0 Td 45.877378 Tz (C. ) Tj 0.621564 0 Td 26.638478 Tz (- ) Tj 0.213108 0 Td 47.357294 Tz (7 ) Tj 0.550529 0 Td 49.471459 Tz (minutes ) Tj 2.131078 0 Td 29.598309 Tz (\) ) Tj 0.443975 0 Td 56.236786 Tz (was ) Tj 1.296406 0 Td 48.837209 Tz (used ) Tj 1.260888 0 Td 11.839323 Tz (. ) Tj 0.372939 0 Td 69.06272 Tz (PCR ) Tj 1.491755 0 Td 46.987315 Tz (products ) Tj 2.557294 0 Td 52.536998 Tz (were ) Tj 1.562791 0 Td 47.110641 Tz (subsequently ) Tj 60 0 0 60 0 1472.123198 Tm 5.4 0 Td 44.444444 Tz (served ) Tj 1.916667 0 Td 51.851852 Tz (domain ) Tj 2.2 0 Td 43.518519 Tz (search ) Tj 1.866667 0 Td 51.851852 Tz (module ) Tj 2.183333 0 Td 51.851852 Tz (was ) Tj 1.266667 0 Td 47.916667 Tz (used ) Tj 1.466667 0 Td 40.740741 Tz (for ) Tj 1.033333 0 Td 45.454545 Tz (determining ) Tj 55.918367 0 0 55.918367 0 1457.3 Tm 23.176642 0 Td 53.223844 Tz (between ) Tj 2.485766 0 Td 54.543796 Tz (mismatched ) Tj 3.487226 0 Td 80.474453 Tz (DNA ) Tj 1.698905 0 Td 29.805353 Tz (\( ) Tj 0.214599 0 Td 49.178832 Tz (95 ) Tj 0.661679 0 Td 32.785888 Tz ( ) Tj 0.50073 0 Td 46.198297 Tz (C. ) Tj 0.643796 0 Td 26.824818 Tz (- ) Tj 0.196715 0 Td 47.688564 Tz (2 ) Tj 0.572263 0 Td 49.817518 Tz (minutes ) Tj 2.145985 0 Td 14.902676 Tz (, ) Tj 0.429197 0 Td 41.727494 Tz (5 ) Tj 0.55438 0 Td 45.204785 Tz (cycles ) Tj 1.931387 0 Td 50.6691 Tz (of ) Tj 57.857143 0 0 57.857143 0 1430.31422 Tm 5.565432 0 Td 48.65112 Tz (conserved ) Tj 2.834568 0 Td 51.440329 Tz (domains ) Tj 2.402469 0 Td 50.411523 Tz (of ) Tj 0.74321 0 Td 44.170096 Tz (the ) Tj 1.019753 0 Td 50.411523 Tz (gene ) Tj 1.209877 0 Td 23.045267 Tz (. ) Tj 57.142857 0 0 57.142857 0 1417 Tm 22.715 0 Td 48.125 Tz (95 ) Tj 0.6475 0 Td 32.083333 Tz ( ) Tj 0.42 0 Td 45.208333 Tz (C. ) Tj 0.63 0 Td 26.25 Tz (- ) Tj 0.1925 0 Td 46.666667 Tz (01 ) Tj 0.8575 0 Td 49.583333 Tz (second ) Tj 1.8025 0 Td 14.583333 Tz (, ) Tj 0.35 0 Td 47.833333 Tz (95-85 ) Tj 1.5225 0 Td 32.083333 Tz ( ) Tj 0.42 0 Td 45.208333 Tz (C. ) Tj 0.6125 0 Td 26.25 Tz (- ) Tj 0.2625 0 Td 29.166667 Tz (1 ) Tj 0.42 0 Td 50.555556 Tz (minute ) Tj 1.995 0 Td 48.854167 Tz (with ) Tj 1.365 0 Td 43.75 Tz (a ) Tj 0.4725 0 Td 46.302083 Tz (decrease ) Tj 2.415 0 Td 49.583333 Tz (of ) Tj 0.7175 0 Td 46.666667 Tz (2 ) Tj 0.35 0 Td 32.083333 Tz ( ) Tj 58.839286 0 0 58.839286 0 1379.433083 Tm 22.0261 0 Td 43.904906 Tz (C. ) Tj 0.917754 0 Td 45.321194 Tz (per ) Tj 1.172686 0 Td 43.621649 Tz (cycle ) Tj 1.359636 0 Td 14.162873 Tz (, ) Tj 0.492868 0 Td 49.09796 Tz (and ) Tj 1.291654 0 Td 48.153768 Tz (60 ) Tj 0.951745 0 Td 42.960715 Tz (cycles ) Tj 1.954476 0 Td 46.737481 Tz (of ) Tj 0.883763 0 Td 47.020738 Tz (85-25 ) Tj 1.495599 0 Td 31.158321 Tz ( ) Tj 0.577845 0 Td 43.904906 Tz (C. ) Tj 0.594841 0 Td 25.493171 Tz (- ) Tj 0.288923 0 Td 43.904906 Tz (10 ) Tj 0.917754 0 Td 46.535154 Tz (seconds ) Tj 1.988467 0 Td 28.325746 Tz (\) ) Tj 0.254932 0 Td 11.330298 Tz (. ) Tj 57.142857 0 0 57.142857 0 1358.493243 Tm 12.0575 0 Td 55.416667 Tz (Example ) Tj 2.555 0 Td 43.75 Tz (3 ) Tj 55.714286 0 0 55.714286 0 1340.891089 Tm 23.279487 0 Td 69.551282 Tz (Home ) Tj 1.705128 0 Td 20.940171 Tz (- ) Tj 0.053846 0 Td 63.568376 Tz (made ) Tj 1.776923 0 Td 49.85755 Tz (Cel ) Tj 0.951282 0 Td 26.923077 Tz (- ) Tj 0.215385 0 Td 29.91453 Tz (I ) Tj 0.448718 0 Td 49.85755 Tz (endonuclease ) Tj 3.823077 0 Td 56.837607 Tz (was ) Tj 1.292308 0 Td 45.204179 Tz (extracted ) Tj 2.692308 0 Td 53.098291 Tz (from ) Tj 1.525641 0 Td 44.871795 Tz (celery ) Tj 62.857143 0 0 62.857143 0 1300.504253 Tm 20.634091 0 Td 46.843434 Tz (and ) Tj 1.018182 0 Td 43.897306 Tz (optimized ) Tj 2.513636 0 Td 42.424242 Tz (using ) Tj 1.463636 0 Td 39.772727 Tz (a ) Tj 0.429545 0 Td 65.293561 Tz (SURVEYOR ) Tj 3.293182 0 Td 45.407197 Tz (Mutation ) Tj 2.338636 0 Td 42.718855 Tz (Detection ) Tj 2.465909 0 Td 41.540404 Tz (Kit ) Tj 61.071429 0 0 61.071429 0 1262.31384 Tm 8.007018 0 Td 45.02924 Tz (Real ) Tj 1.146199 0 Td 24.561404 Tz (- ) Tj 0.180117 0 Td 51.851852 Tz (Time ) Tj 1.473684 0 Td 41.845354 Tz (Quantitative ) Tj 3.242105 0 Td 62.768031 Tz (PCR ) Tj 1.375439 0 Td 27.290448 Tz (\( ) Tj 0.180117 0 Td 60.721248 Tz (qPCR ) Tj 1.473684 0 Td 27.290448 Tz (\) ) Tj 57.142857 0 0 57.142857 0 1263.118537 Tm 22.715 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 49.583333 Tz (Cat ) Tj 0.945 0 Td 11.666667 Tz (. ) Tj 0.28 0 Td 51.527778 Tz (No. ) Tj 1.1375 0 Td 53.958333 Tz (706020 ) Tj 1.9775 0 Td 14.583333 Tz (, ) Tj 0.2975 0 Td 51.041667 Tz (Transgenomic ) Tj 3.885 0 Td 39.375 Tz (Inc. ) Tj 1.015 0 Td 14.583333 Tz (, ) Tj 0.2975 0 Td 63 Tz (Omaha ) Tj 1.8725 0 Td 26.25 Tz (, ) Tj 0.3325 0 Td 54.6875 Tz (Nebr ) Tj 1.33 0 Td 11.666667 Tz (. ) Tj 0.14 0 Td 14.583333 Tz (, ) Tj 0.28 0 Td 72.916667 Tz (USA ) Tj 1.33 0 Td 29.166667 Tz (\) ) Tj 0.2625 0 Td 11.666667 Tz (. ) Tj 63.333333 0 0 63.333333 0 1225.586788 Tm 20.463158 0 Td 55.263158 Tz (Two ) Tj 1.247368 0 Td 35.526316 Tz (ul ) Tj 0.663158 0 Td 44.736842 Tz (of ) Tj 0.694737 0 Td 42.982456 Tz (Cel ) Tj 0.836842 0 Td 23.684211 Tz (- ) Tj 0.173684 0 Td 26.315789 Tz (I ) Tj 0.363158 0 Td 50.877193 Tz (was ) Tj 1.136842 0 Td 47.368421 Tz (added ) Tj 1.610526 0 Td 35.526316 Tz (to ) Tj 0.663158 0 Td 39.473684 Tz (the ) Tj 0.915789 0 Td 43.421053 Tz (heteroduplexed ) Tj 3.821053 0 Td 42.434211 Tz (products ) Tj 57.619048 0 0 57.619048 0 1177.740741 Tm 6.265289 0 Td 42.231405 Tz (Total ) Tj 1.544628 0 Td 75.206612 Tz (RNA ) Tj 1.561983 0 Td 53.99449 Tz (was ) Tj 1.249587 0 Td 44.031221 Tz (extracted ) Tj 2.603306 0 Td 46.280992 Tz (using ) Tj 1.64876 0 Td 63.15427 Tz (TRIZOL ) Tj 2.499174 0 Td 45.454545 Tz (reagent ) Tj 2.204132 0 Td 34.710744 Tz (\( ) Tj 0.22562 0 Td 45.702479 Tz (Invit ) Tj 51.428571 0 0 51.428571 0 1188 Tm 25.219444 0 Td 57.253086 Tz (and ) Tj 1.380556 0 Td 52.211934 Tz (incubated ) Tj 3.169444 0 Td 42.12963 Tz (at ) Tj 0.855556 0 Td 55.092593 Tz (45 ) Tj 0.758333 0 Td 35.648148 Tz ( ) Tj 0.602778 0 Td 50.231481 Tz (C. ) Tj 1.011111 0 Td 46.450617 Tz (for ) Tj 1.186111 0 Td 53.472222 Tz (45 ) Tj 1.030556 0 Td 54.62963 Tz (minutes ) Tj 2.333333 0 Td 22.685185 Tz (. ) Tj 0.505556 0 Td 52.572016 Tz (Reactions ) Tj 3.188889 0 Td 58.333333 Tz (were ) Tj 65.714286 0 0 65.714286 0 1130.501229 Tm 4.9 0 Td 40.57971 Tz (rogen ) Tj 1.263043 0 Td 25.362319 Tz (, ) Tj 0.380435 0 Td 41.213768 Tz (Carlsbad ) Tj 2.008696 0 Td 30.434783 Tz (, ) Tj 0.334783 0 Td 38.043478 Tz (Calif ) Tj 1.141304 0 Td 30.434783 Tz (. ) Tj 0.091304 0 Td 30.434783 Tz (, ) Tj 0.258696 0 Td 65.942029 Tz (USA ) Tj 1.232609 0 Td 30.434783 Tz (\) ) Tj 0.41087 0 Td 44.806763 Tz (and ) Tj 1.004348 0 Td 65.942029 Tz (RNA ) Tj 1.354348 0 Td 37.137681 Tz (quantification ) Tj 3.302174 0 Td 48.188406 Tz (was ) Tj 57.142857 0 0 57.142857 0 1148.8 Tm 22.715 0 Td 47.916667 Tz (stopped ) Tj 2.275 0 Td 47.25 Tz (using ) Tj 1.715 0 Td 41.805556 Tz (2.5 ) Tj 1.1025 0 Td 39.375 Tz (ul ) Tj 0.7875 0 Td 57.604167 Tz (0.5M ) Tj 1.68 0 Td 61.979167 Tz (EDTA ) Tj 1.6975 0 Td 20.416667 Tz (. ) Tj 0.42 0 Td 55.416667 Tz (The ) Tj 1.3125 0 Td 45.208333 Tz (digested ) Tj 2.4325 0 Td 46.302083 Tz (products ) Tj 84.480519 0 0 84.480519 0 1075.102915 Tm 3.81153 0 Td 37.483987 Tz (done ) Tj 0.935127 0 Td 34.524725 Tz (with ) Tj 0.970638 0 Td 35.26454 Tz (Nanodrop ) Tj 1.692698 0 Td 35.511145 Tz (- ) Tj 0.224904 0 Td 33.045094 Tz (1000 ) Tj 0.911453 0 Td 35.511145 Tz (\( ) Tj 0.224904 0 Td 36.497566 Tz (Thermo ) Tj 1.420446 0 Td 27.027927 Tz (Scientific ) Tj 1.680861 0 Td 31.565462 Tz (\) ) Tj 0.11837 0 Td 31.565462 Tz (. ) Tj 0.224904 0 Td 51.95149 Tz (RNA ) Tj 0.982475 0 Td 29.592621 Tz (quality ) Tj 1.503305 0 Td 27.61978 Tz (45 ) Tj 0.710223 0 Td 27.61978 Tz (identified ) Tj 1.787394 0 Td 33.538304 Tz (as ) Tj 0.568178 0 Td 29.592621 Tz (those ) Tj 1.12452 0 Td 31.565462 Tz (products ) Tj 1.728209 0 Td 29.099411 Tz (that ) Tj 0.698386 0 Td 39.128021 Tz (showed ) Tj 1.56249 0 Td 32.410966 Tz (cleaved ) Tj 1.515142 0 Td 34.722009 Tz (bands ) Tj 1.100846 0 Td 38.470407 Tz (in ) Tj 58.571429 0 0 58.571429 0 1108.146444 Tm 22.126829 0 Td 51.219512 Tz (were ) Tj 1.587805 0 Td 43.252033 Tz (visualized ) Tj 2.953659 0 Td 51.219512 Tz (on ) Tj 0.973171 0 Td 45.528455 Tz (2 ) Tj 0.32439 0 Td 82.520325 Tz (% ) Tj 0.870732 0 Td 45.934959 Tz (agarose ) Tj 2.304878 0 Td 41.260163 Tz (gels ) Tj 1.058537 0 Td 11.382114 Tz (. ) Tj 0.478049 0 Td 48.780488 Tz (Mutants ) Tj 2.42439 0 Td 47.235772 Tz (could ) Tj 1.758537 0 Td 48.373984 Tz (be ) Tj 62.857143 0 0 62.857143 0 1056.340169 Tm 5.122727 0 Td 50.378788 Tz (was ) Tj 1.129545 0 Td 44.545455 Tz (determined ) Tj 2.847727 0 Td 42.424242 Tz (using ) Tj 1.495455 0 Td 43.38843 Tz (Bioanalyzer ) Tj 3.070455 0 Td 26.515152 Tz (\( ) Tj 0.222727 0 Td 41.287879 Tz (Agilent ) Tj 1.925 0 Td 43.851981 Tz (Technologoies ) Tj 3.404545 0 Td 26.515152 Tz (, ) Tj 62.857143 0 0 62.857143 0 1012.986198 Tm 5.122727 0 Td 66.287879 Tz (USA ) Tj 1.209091 0 Td 26.515152 Tz (\) ) Tj 0.222727 0 Td 10.606061 Tz (. ) Tj 0.302273 0 Td 35.530303 Tz (First ) Tj 1.272727 0 Td 39.772727 Tz (strand ) Tj 1.622727 0 Td 63.636364 Tz (cDNA ) Tj 1.670455 0 Td 50.378788 Tz (was ) Tj 1.129545 0 Td 41.701102 Tz (synthesized ) Tj 2.927273 0 Td 42.424242 Tz (using ) Tj 1.463636 0 Td 39.772727 Tz (the ) Tj 0.922727 0 Td 53.030303 Tz (Super ) Tj 62.207792 0 0 62.207792 0 1029.56539 Tm 20.849478 0 Td 40.85769 Tz (addition ) Tj 2.298747 0 Td 37.508699 Tz (to ) Tj 0.819833 0 Td 40.187891 Tz (the ) Tj 1.093111 0 Td 38.178497 Tz (full ) Tj 0.884134 0 Td 29.47112 Tz (- ) Tj 0.208977 0 Td 37.062167 Tz (length ) Tj 1.366388 0 Td 29.47112 Tz (, ) Tj 0.56263 0 Td 45.248589 Tz (uncleaved ) Tj 2.781002 0 Td 42.063326 Tz (production ) Tj 2.572025 0 Td 32.150313 Tz (. ) Tj 0.546555 0 Td 42.331246 Tz (Forty ) Tj 60 0 0 60 0 974.596469 Tm 5.4 0 Td 42.708333 Tz (ScriptTM ) Tj 2.283333 0 Td 31.666667 Tz (first ) Tj 1.183333 0 Td 41.203704 Tz (strand ) Tj 1.7 0 Td 66.666667 Tz (cDNA ) Tj 1.8 0 Td 41.049383 Tz (synthesis ) Tj 2.45 0 Td 36.111111 Tz (kit ) Tj 0.883333 0 Td 27.777778 Tz (\( ) Tj 0.233333 0 Td 41.388889 Tz (Invitrogen ) Tj 2.483333 0 Td 27.777778 Tz (, ) Tj 0.45 0 Td 48.333333 Tz (Carls ) Tj 60 0 0 60 0 989.960811 Tm 21.6 0 Td 46.428571 Tz (mutants ) Tj 2.216667 0 Td 50 Tz (were ) Tj 1.483333 0 Td 48.333333 Tz (found ) Tj 1.7 0 Td 40.277778 Tz (in ) Tj 0.716667 0 Td 41.666667 Tz (the ) Tj 1.016667 0 Td 58.333333 Tz (TILLING ) Tj 2.7 0 Td 43.888889 Tz (pools ) Tj 1.4 0 Td 11.111111 Tz (. ) Tj 0.316667 0 Td 75 Tz (A ) Tj 0.666667 0 Td 36.111111 Tz (total ) Tj 1.383333 0 Td 45.833333 Tz (of ) Tj 0.766667 0 Td 48.611111 Tz (40 ) Tj 57.142857 0 0 57.142857 0 953.542553 Tm 22.68 0 Td 48.75 Tz (mutants ) Tj 2.345 0 Td 52.5 Tz (were ) Tj 1.5575 0 Td 50.75 Tz (found ) Tj 1.8025 0 Td 53.958333 Tz (on ) Tj 0.9275 0 Td 53.958333 Tz (4x ) Tj 0.945 0 Td 46.083333 Tz (pools ) Tj 1.6975 0 Td 49.583333 Tz (of ) Tj 0.805 0 Td 43.75 Tz (the ) Tj 1.085 0 Td 40.833333 Tz (entire ) Tj 1.75 0 Td 46.666667 Tz (population ) Tj 61.428571 0 0 61.428571 0 929.366492 Tm 5.24186 0 Td 48.837209 Tz (bad ) Tj 0.911628 0 Td 13.565891 Tz (, ) Tj 0.325581 0 Td 41.782946 Tz (Calif ) Tj 1.237209 0 Td 24.418605 Tz (. ) Tj 0.113953 0 Td 24.418605 Tz (, ) Tj 0.35814 0 Td 66.925065 Tz (USA ) Tj 1.22093 0 Td 27.131783 Tz (\) ) Tj 0.390698 0 Td 43.410853 Tz (using ) Tj 1.546512 0 Td 37.984496 Tz (5 ) Tj 0.472093 0 Td 48.837209 Tz (ug ) Tj 0.781395 0 Td 35.271318 Tz (total ) Tj 1.302326 0 Td 65.116279 Tz (RNA ) Tj 1.269767 0 Td 18.992248 Tz (. ) Tj 0.35814 0 Td 41.375969 Tz (Quantitative ) Tj 3.206977 0 Td 62.403101 Tz (PCR ) Tj 60 0 0 60 0 913.321809 Tm 21.633333 0 Td 44.791667 Tz (screened ) Tj 2.2 0 Td 11.111111 Tz (. ) Tj 0.5 0 Td 43.402778 Tz (Selected ) Tj 2.433333 0 Td 44.444444 Tz (pools ) Tj 1.716667 0 Td 50 Tz (were ) Tj 1.6 0 Td 46.527778 Tz (deconvoluted ) Tj 3.7 0 Td 37.5 Tz (to ) Tj 0.866667 0 Td 39.583333 Tz (identify ) Tj 55.714286 0 0 55.714286 0 891 Tm 5.779487 0 Td 56.837607 Tz (was ) Tj 1.274359 0 Td 44.017094 Tz (carried ) Tj 2.082051 0 Td 46.866097 Tz (out ) Tj 1.076923 0 Td 55.34188 Tz (on ) Tj 0.897436 0 Td 50.356125 Tz (Biorad ) Tj 2.028205 0 Td 64.615385 Tz (CFX96 ) Tj 2.189744 0 Td 40.384615 Tz (real ) Tj 1.220513 0 Td 49.358974 Tz (time ) Tj 1.417949 0 Td 69.80057 Tz (PCR ) Tj 1.489744 0 Td 45.536562 Tz (detection ) Tj 65.714286 0 0 65.714286 0 876.598531 Tm 18.930435 0 Td 34.23913 Tz (50 ) Tj 0.791304 0 Td 43.538647 Tz (mutant ) Tj 1.81087 0 Td 37.812912 Tz (individuals ) Tj 2.73913 0 Td 46.666667 Tz (which ) Tj 1.613043 0 Td 46.286232 Tz (were ) Tj 1.33913 0 Td 40.57971 Tz (then ) Tj 1.232609 0 Td 43.397746 Tz (sequenced ) Tj 2.556522 0 Td 46.92029 Tz (by ) Tj 0.821739 0 Td 43.538647 Tz (Sanger ) Tj 62.857143 0 0 62.857143 0 850.617756 Tm 5.154545 0 Td 45.075758 Tz (system ) Tj 1.781818 0 Td 42.954545 Tz (using ) Tj 1.479545 0 Td 47.727273 Tz (IQTM ) Tj 1.352273 0 Td 65.227273 Tz (SYBR ) Tj 2.163636 0 Td 47.727273 Tz (Green ) Tj 1.622727 0 Td 47.395833 Tz (Supermix ) Tj 2.481818 0 Td 26.515152 Tz (\( ) Tj 0.175 0 Td 50.378788 Tz (BioRad ) Tj 1.845455 0 Td 13.257576 Tz (, ) Tj 0.286364 0 Td 62.752525 Tz (Her ) Tj 61.785714 0 0 61.785714 0 840.547523 Tm 20.991908 0 Td 44.508671 Tz (sequencing ) Tj 2.63815 0 Td 26.974952 Tz (. ) Tj 0.598844 0 Td 47.880539 Tz (Sequence ) Tj 2.686705 0 Td 39.788054 Tz (analysis ) Tj 2.330636 0 Td 50.353243 Tz (was ) Tj 1.310983 0 Td 47.880539 Tz (done ) Tj 1.537572 0 Td 43.699422 Tz (using ) Tj 1.699422 0 Td 40.077071 Tz (Clustal ) Tj 58.571429 0 0 58.571429 0 811.052198 Tm 5.514634 0 Td 42.113821 Tz (cules ) Tj 1.331707 0 Td 14.227642 Tz (, ) Tj 0.341463 0 Td 71.138211 Tz (USA ) Tj 1.297561 0 Td 28.455285 Tz (\) ) Tj 0.256098 0 Td 11.382114 Tz (. ) Tj 0.32439 0 Td 54.065041 Tz (The ) Tj 1.229268 0 Td 65.447154 Tz (PCR ) Tj 1.417073 0 Td 44.390244 Tz (cycle ) Tj 1.553659 0 Td 49.085366 Tz (used ) Tj 1.417073 0 Td 40.785908 Tz (for ) Tj 0.973171 0 Td 62.601626 Tz (qPCR ) Tj 1.72439 0 Td 54.065041 Tz (was ) Tj 1.246341 0 Td 46.95122 Tz (95 ) Tj 0.64878 0 Td 31.300813 Tz ( ) Tj 0.460976 0 Td 44.105691 Tz (C. ) Tj 0.597561 0 Td 25.609756 Tz (- ) Tj 0.204878 0 Td 42.682927 Tz (3 ) Tj 67.142857 0 0 67.142857 0 798.93865 Tm 19.317021 0 Td 52.624113 Tz (Omega ) Tj 1.846809 0 Td 29.787234 Tz (\( ) Tj 0.16383 0 Td 40.047281 Tz (www.clustal.org ) Tj 3.634043 0 Td 29.787234 Tz (\) ) Tj 0.417021 0 Td 36.406619 Tz (for ) Tj 0.789362 0 Td 44.060284 Tz (sequence ) Tj 2.338298 0 Td 43.301812 Tz (alignment ) Tj 2.47234 0 Td 44.680851 Tz (and ) Tj 1.012766 0 Td 38.061466 Tz (the ) Tj 55.966387 0 0 55.966387 0 770.090791 Tm 5.735586 0 Td 51.051051 Tz (minutes ) Tj 2.090541 0 Td 26.801802 Tz (, ) Tj 0.375225 0 Td 52.114615 Tz (44 ) Tj 0.83979 0 Td 45.165999 Tz (cycles ) Tj 1.84039 0 Td 50.625626 Tz (of ) Tj 0.75045 0 Td 49.136637 Tz (95 ) Tj 0.678979 0 Td 32.757758 Tz ( ) Tj 0.410961 0 Td 46.158659 Tz (C. ) Tj 0.625375 0 Td 26.801802 Tz (- ) Tj 0.268018 0 Td 46.158659 Tz (15 ) Tj 0.804054 0 Td 48.923924 Tz (seconds ) Tj 2.269219 0 Td 52.610944 Tz (and ) Tj 1.143544 0 Td 52.114615 Tz (60 ) Tj 0.678979 0 Td 32.757758 Tz ( ) Tj 0.410961 0 Td 55.092593 Tz (C. ) Tj 0.714715 0 Td 23.823824 Tz (- ) Tj 0.214414 0 Td 45.945946 Tz (lminute ) Tj 60.15873 0 0 60.15873 0 762.795862 Tm 21.526385 0 Td 42.348285 Tz (protein ) Tj 1.9781 0 Td 39.094107 Tz (translate ) Tj 2.327177 0 Td 38.78628 Tz (tool ) Tj 1.180211 0 Td 47.097625 Tz (of ) Tj 0.731398 0 Td 57.255937 Tz (ExPASy ) Tj 2.310554 0 Td 30.474934 Tz (\( ) Tj 0.166227 0 Td 48.680739 Tz (www.expasy.org ) Tj 4.188918 0 Td 27.704485 Tz (\) ) Tj 0.099736 0 Td 27.704485 Tz (. ) Tj 57.293233 0 0 57.293233 0 729.788171 Tm 5.602756 0 Td 48.725941 Tz (with ) Tj 1.361417 0 Td 41.889764 Tz (plate ) Tj 1.466142 0 Td 46.544182 Tz (read ) Tj 1.326509 0 Td 37.817148 Tz (at ) Tj 0.663255 0 Td 47.707787 Tz (every ) Tj 1.658136 0 Td 41.453412 Tz (step ) Tj 1.064698 0 Td 14.545057 Tz (, ) Tj 0.331627 0 Td 50.422864 Tz (and ) Tj 1.151969 0 Td 47.998688 Tz (95 ) Tj 0.663255 0 Td 31.999125 Tz ( ) Tj 0.436352 0 Td 58.180227 Tz (C. ) Tj 0.663255 0 Td 20.36308 Tz (- ) Tj 0.226903 0 Td 40.726159 Tz (10 ) Tj 0.610892 0 Td 20.36308 Tz (" ) Tj 0.209449 0 Td 20.36308 Tz (. ) Tj 0.331627 0 Td 53.81671 Tz (At ) Tj 0.837795 0 Td 43.635171 Tz (the ) Tj 1.012336 0 Td 51.392534 Tz (end ) Tj 1.134514 0 Td 49.453193 Tz (of ) Tj 58.571429 0 0 58.571429 0 688.384 Tm 5.497561 0 Td 42.682927 Tz (the ) Tj 1.041463 0 Td 43.821138 Tz (cycle ) Tj 1.365854 0 Td 14.227642 Tz (, ) Tj 0.37561 0 Td 46.95122 Tz (melt ) Tj 1.382927 0 Td 46.666667 Tz (curve ) Tj 1.673171 0 Td 41.971545 Tz (analysis ) Tj 2.287805 0 Td 53.116531 Tz (was ) Tj 1.246341 0 Td 50.50813 Tz (done ) Tj 1.468293 0 Td 38.414634 Tz (to ) Tj 0.75122 0 Td 47.154472 Tz (confirm ) Tj 2.253659 0 Td 49.512195 Tz (speci ) Tj 55.714286 0 0 55.714286 0 691.178082 Tm 29.866667 0 Td 55.982906 Tz (Example ) Tj 2.620513 0 Td 44.871795 Tz (6 ) Tj 58.831169 0 0 58.831169 0 648.571238 Tm 5.473289 0 Td 35.412068 Tz (ficity ) Tj 1.580795 0 Td 48.160412 Tz (of ) Tj 0.781898 0 Td 46.035688 Tz (products ) Tj 2.15872 0 Td 28.329654 Tz (. ) Tj 0.424945 0 Td 43.438803 Tz (All ) Tj 1.087859 0 Td 41.864933 Tz (reactions ) Tj 2.566667 0 Td 50.993377 Tz (were ) Tj 1.512804 0 Td 41.685063 Tz (carried ) Tj 2.039735 0 Td 43.438803 Tz (out ) Tj 1.087859 0 Td 39.661516 Tz (in ) Tj 0.747903 0 Td 41.927888 Tz (three ) Tj 57.142857 0 0 57.142857 0 609.329177 Tm 5.635 0 Td 43.425926 Tz (technical ) Tj 2.6425 0 Td 41.416667 Tz (replicates ) Tj 2.8 0 Td 48.125 Tz (over ) Tj 1.435 0 Td 43.166667 Tz (three ) Tj 1.575 0 Td 43.166667 Tz (biological ) Tj 2.905 0 Td 42 Tz (replicates ) Tj 2.45 0 Td 29.166667 Tz (. ) Tj 0.455 0 Td 49 Tz (Actin ) Tj 63.428571 0 0 63.428571 0 604.129293 Tm 23.175676 0 Td 42.042042 Tz (Antifungal ) Tj 2.711712 0 Td 40.071321 Tz (Activity ) Tj 2.144144 0 Td 44.66967 Tz (of ) Tj 0.693694 0 Td 46.64039 Tz (Fhb1 ) Tj 1.403153 0 Td 40.540541 Tz (Protein ) Tj 60 0 0 60 0 565.513716 Tm 5.366667 0 Td 52.777778 Tz (was ) Tj 1.15 0 Td 47.916667 Tz (used ) Tj 1.333333 0 Td 40.277778 Tz (as ) Tj 0.7 0 Td 38.888889 Tz (internal ) Tj 2.066667 0 Td 42.901235 Tz (reference ) Tj 2.516667 0 Td 42.857143 Tz (control ) Tj 1.783333 0 Td 19.444444 Tz (. ) Tj 0.3 0 Td 52.777778 Tz (The ) Tj 1.15 0 Td 44.444444 Tz (following ) Tj 2.633333 0 Td 55.555556 Tz (prim ) Tj 58.503401 0 0 58.503401 0 521.465753 Tm 5.521047 0 Td 38.934109 Tz (ers ) Tj 0.854651 0 Td 51.27907 Tz (were ) Tj 1.384535 0 Td 49.142442 Tz (used ) Tj 1.316163 0 Td 40.833333 Tz (for ) Tj 0.871744 0 Td 63.386628 Tz (qPCR ) Tj 1.64093 0 Td 42.416021 Tz (reactions ) Tj 2.358837 0 Td 11.395349 Tz (: ) Tj 0.290581 0 Td 50.56686 Tz (Fhbl ) Tj 1.435814 0 Td 49.142442 Tz (gene ) Tj 1.333256 0 Td 48.023256 Tz (forward ) Tj 2.153721 0 Td 47.48062 Tz (primer ) Tj 3.640814 0 Td 54.127907 Tz (The ) Tj 1.281977 0 Td 43.139535 Tz (protein ) Tj 2.119535 0 Td 53.178295 Tz (was ) Tj 1.29907 0 Td 43.365633 Tz (extracted ) Tj 2.649419 0 Td 51.27907 Tz (from ) Tj 1.521279 0 Td 43.682171 Tz (pre ) Tj 0.923023 0 Td 28.488372 Tz (- ) Tj 0.188023 0 Td 40.952035 Tz (anthesis ) Tj 2.324651 0 Td 42.732558 Tz (spikes ) Tj 1.880233 0 Td 48.430233 Tz (of ) Tj 58.190476 0 0 58.190476 0 481.122691 Tm 5.567921 0 Td 31.505728 Tz (\( ) Tj 0.274959 0 Td 28.641571 Tz (5 ) Tj 0.274959 0 Td 28.641571 Tz (' ) Tj 0.13748 0 Td 28.641571 Tz (- ) Tj 0.171849 0 Td 71.174304 Tz (CGCACCAATGTGGAGTACAG ) Tj 8.798691 0 Td 28.641571 Tz (- ) Tj 0.274959 0 Td 28.641571 Tz (3 ) Tj 0.120295 0 Td 28.641571 Tz (' ) Tj 0.463993 0 Td 28.641571 Tz (\( ) Tj 0.206219 0 Td 64.920895 Tz (SEQ ) Tj 1.42635 0 Td 54.418985 Tz (ID ) Tj 0.893617 0 Td 75.900164 Tz (NO ) Tj 0.979542 0 Td 11.456628 Tz (: ) Tj 0.206219 0 Td 45.826514 Tz (10 ) Tj 0.584288 0 Td 28.641571 Tz (\) ) Tj 0.206219 0 Td 28.641571 Tz (\) ) Tj 0.257774 0 Td 14.320786 Tz (; ) Tj 1.42635 0 Td 39.46172 Tz (resistant ) Tj 2.526187 0 Td 46.542553 Tz (near ) Tj 1.512275 0 Td 43.678396 Tz (isogenic ) Tj 2.543372 0 Td 38.666121 Tz (line ) Tj 1.35761 0 Td 28.641571 Tz (\( ) Tj 0.206219 0 Td 68.739771 Tz (R ) Tj 0.446809 0 Td 25.777414 Tz (- ) Tj 0.171849 0 Td 59.19258 Tz (NIL ) Tj 1.099836 0 Td 28.641571 Tz (\) ) Tj 0.240589 0 Td 11.456628 Tz (. ) Tj 0.498363 0 Td 52.509547 Tz (Twenty ) Tj 2.337152 0 Td 42.962357 Tz (spikes ) Tj 1.976268 0 Td 48.690671 Tz (of ) Tj 45.714286 0 0 45.714286 0 449 Tm 7.065625 0 Td 64.713542 Tz (Fhb1 ) Tj 42.857143 0 0 42.857143 0 448 Tm 11.736667 0 Td 67.083333 Tz (gene ) Tj 57.669173 0 0 57.669173 0 442.715635 Tm 15.363494 0 Td 48.649138 Tz (primer ) Tj 3.554759 0 Td 28.900478 Tz (\( ) Tj 0.294785 0 Td 28.900478 Tz (5 ) Tj 0.242764 0 Td 28.900478 Tz (' ) Tj 0.190743 0 Td 28.900478 Tz (- ) Tj 0.156063 0 Td 56.355932 Tz (CAT- ) Tj 2.687744 0 Td 69.361147 Tz (R ) Tj 0.450847 0 Td 26.01043 Tz (- ) Tj 0.173403 0 Td 59.727655 Tz (NIL ) Tj 1.421904 0 Td 51.298349 Tz (were ) Tj 1.595306 0 Td 43.029601 Tz (collected ) Tj 2.687744 0 Td 37.570621 Tz (at ) Tj 0.797653 0 Td 46.240765 Tz (pre ) Tj 0.953716 0 Td 28.900478 Tz (- ) Tj 0.208083 0 Td 40.460669 Tz (anthesis ) Tj 2.340939 0 Td 43.350717 Tz (stage ) Tj 1.335202 0 Td 14.450239 Tz (, ) Tj 0.485528 0 Td 52.02086 Tz (and ) Tj 1.283181 0 Td 50.094162 Tz (ground ) Tj 60 0 0 60 0 401.750164 Tm 5.366667 0 Td 71.875 Tz (AGAGGCGGCAGTAGGG ) Tj 7.1 0 Td 19.444444 Tz (- ) Tj 0.283333 0 Td 19.444444 Tz (3 ) Tj 0.133333 0 Td 19.444444 Tz (' ) Tj 0.583333 0 Td 27.777778 Tz (\( ) Tj 0.2 0 Td 62.962963 Tz (SEQ ) Tj 1.583333 0 Td 51.388889 Tz (ID ) Tj 1.05 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.2 0 Td 37.5 Tz (11 ) Tj 0.55 0 Td 27.777778 Tz (\) ) Tj 0.2 0 Td 27.777778 Tz (\) ) Tj 0.25 0 Td 13.888889 Tz (; ) Tj 0.5 0 Td 46.666667 Tz (Actin ) Tj 2.65 0 Td 44.444444 Tz (using ) Tj 1.566667 0 Td 40.277778 Tz (liquid ) Tj 1.65 0 Td 40.972222 Tz (nitrogen ) Tj 2.066667 0 Td 27.777778 Tz (. ) Tj 0.383333 0 Td 52.777778 Tz (The ) Tj 1.166667 0 Td 42.063492 Tz (protein ) Tj 1.966667 0 Td 52.777778 Tz (was ) Tj 1.2 0 Td 41.975309 Tz (extracted ) Tj 2.466667 0 Td 45 Tz (using ) Tj 1.583333 0 Td 50 Tz (400 ) Tj 56.868132 0 0 56.868132 0 363.990666 Tm 5.662222 0 Td 50.555556 Tz (gene ) Tj 1.441932 0 Td 49.404187 Tz (forward ) Tj 2.268406 0 Td 48.845947 Tz (primer ) Tj 2.004638 0 Td 32.238325 Tz (\( ) Tj 0.228599 0 Td 32.238325 Tz (5 ) Tj 0.281353 0 Td 32.238325 Tz (' ) Tj 0.175845 0 Td 32.238325 Tz (- ) Tj 0.246184 0 Td 72.80617 Tz (TGACCGTATGAGCAAGGAG ) Tj 8.563671 0 Td 32.238325 Tz (- ) Tj 0.19343 0 Td 32.238325 Tz (3 ) Tj 0.175845 0 Td 32.238325 Tz (' ) Tj 1.54744 0 Td 55.68438 Tz (ml ) Tj 0.826473 0 Td 54.219002 Tz (of ) Tj 0.738551 0 Td 48.650564 Tz (0.15M ) Tj 1.828792 0 Td 57.149758 Tz (NaCl ) Tj 1.54744 0 Td 42.007515 Tz (for ) Tj 0.949565 0 Td 46.89211 Tz (16 ) Tj 0.738551 0 Td 47.478261 Tz (hours ) Tj 1.617778 0 Td 36.634461 Tz (at ) Tj 0.615459 0 Td 46.89211 Tz (4 ) Tj 0.334106 0 Td 32.238325 Tz ( ) Tj 0.38686 0 Td 57.882448 Tz (C.on ) Tj 1.54744 0 Td 43.961353 Tz (a ) Tj 0.404444 0 Td 49.822866 Tz (magnetic ) Tj 2.584928 0 Td 37.681159 Tz (stirrer ) Tj 1.565024 0 Td 20.515298 Tz (. ) Tj 59.89011 0 0 59.89011 0 324.45328 Tm 5.409908 0 Td 27.828746 Tz (\( ) Tj 0.217064 0 Td 62.150866 Tz (SEQ ) Tj 1.486055 0 Td 52.874618 Tz (ID ) Tj 0.96844 0 Td 75.137615 Tz (NO ) Tj 0.96844 0 Td 11.131498 Tz (: ) Tj 0.18367 0 Td 44.525994 Tz (12 ) Tj 0.567706 0 Td 27.828746 Tz (\) ) Tj 0.217064 0 Td 27.828746 Tz (\) ) Tj 0.233761 0 Td 13.914373 Tz (; ) Tj 0.417431 0 Td 46.752294 Tz (Actin ) Tj 1.753211 0 Td 48.004587 Tz (gene ) Tj 1.486055 0 Td 42.538226 Tz (reverse ) Tj 2.137248 0 Td 46.381244 Tz (primer ) Tj 2.103853 0 Td 33.394495 Tz (\( ) Tj 0.200367 0 Td 33.394495 Tz (5 ) Tj 0.283853 0 Td 33.394495 Tz (' ) Tj 0.133578 0 Td 33.394495 Tz (- ) Tj 0.217064 0 Td 59.136086 Tz (CCA- ) Tj 2.654862 0 Td 62.962538 Tz (Ammonium ) Tj 3.306055 0 Td 42.438838 Tz (sulphate ) Tj 2.320917 0 Td 40.458716 Tz (precipitation ) Tj 3.422936 0 Td 47.308869 Tz (of ) Tj 0.768073 0 Td 42.140673 Tz (protein ) Tj 2.020367 0 Td 52.874618 Tz (was ) Tj 1.252294 0 Td 49.396024 Tz (done ) Tj 1.469358 0 Td 36.17737 Tz (at ) Tj 60.8867 0 0 60.8867 0 283.396644 Tm 5.288511 0 Td 68.111079 Tz (GACAACTCGCAACTTAG ) Tj 7.226537 0 Td 32.847896 Tz (- ) Tj 0.197087 0 Td 32.847896 Tz (3 ) Tj 0.098544 0 Td 32.847896 Tz (' ) Tj 0.70623 0 Td 27.373247 Tz (\( ) Tj 0.213511 0 Td 61.133585 Tz (SEQ ) Tj 1.593123 0 Td 50.640507 Tz (ID ) Tj 1.083981 0 Td 64.327131 Tz (NO ) Tj 0.903317 0 Td 30.110572 Tz (: ) Tj 0.262783 0 Td 41.059871 Tz (13 ) Tj 0.591262 0 Td 30.110572 Tz (\) ) Tj 0.213511 0 Td 30.110572 Tz (\) ) Tj 0.049272 0 Td 30.110572 Tz (. ) Tj 0.673382 0 Td 53.834052 Tz (The ) Tj 2.200809 0 Td 46.53452 Tz (35 ) Tj 0.607686 0 Td 79.382416 Tz (% ) Tj 0.722654 0 Td 39.964941 Tz (saturation ) Tj 2.594984 0 Td 49.271845 Tz (by ) Tj 0.837621 0 Td 44.188242 Tz (shaking ) Tj 2.085841 0 Td 39.234987 Tz (for ) Tj 0.903317 0 Td 43.797195 Tz (2 ) Tj 0.476294 0 Td 44.892125 Tz (hours ) Tj 1.576699 0 Td 35.585221 Tz (at ) Tj 0.640534 0 Td 43.797195 Tz (4 ) Tj 0.328479 0 Td 30.110572 Tz ( ) Tj 0.410599 0 Td 42.428533 Tz (C. ) Tj 0.591262 0 Td 13.686624 Tz (, ) Tj 0.312055 0 Td 50.366775 Tz (which ) Tj 1.691667 0 Td 52.009169 Tz (was ) Tj 72.857143 0 0 72.857143 0 241.561275 Tm 4.433333 0 Td 38.507625 Tz (2-00CT ) Tj 1.468627 0 Td 44.989107 Tz (method ) Tj 1.67451 0 Td 43.464052 Tz (was ) Tj 0.933333 0 Td 39.460784 Tz (used ) Tj 1.070588 0 Td 30.882353 Tz (to ) Tj 0.535294 0 Td 33.805374 Tz (calculate ) Tj 1.94902 0 Td 38.888889 Tz (the ) Tj 0.754902 0 Td 33.627451 Tz (transcript ) Tj 2.058824 0 Td 35.83878 Tz (values ) Tj 1.454902 0 Td 38.888889 Tz (of ) Tj 0.754902 0 Td 28.594771 Tz (65 ) Tj 0.713725 0 Td 37.745098 Tz (followed ) Tj 2.003922 0 Td 42.320261 Tz (by ) Tj 0.727451 0 Td 34.504357 Tz (centrifuging ) Tj 2.566667 0 Td 41.176471 Tz (at ) Tj 0.754902 0 Td 38.126362 Tz (17,000 ) Tj 1.633333 0 Td 34.313725 Tz (g ) Tj 0.384314 0 Td 36.601307 Tz (for ) Tj 0.796078 0 Td 41.176471 Tz (20 ) Tj 0.727451 0 Td 39.215686 Tz (minutes ) Tj 1.67451 0 Td 34.313725 Tz (. ) Tj 0.260784 0 Td 42.701525 Tz (The ) Tj 59.714286 0 0 59.714286 0 211.030208 Tm 5.392344 0 Td 41.866029 Tz (the ) Tj 0.954545 0 Td 46.650718 Tz (samples ) Tj 1.992823 0 Td 27.910686 Tz (. ) Tj 0.334928 0 Td 50.239234 Tz (Changes ) Tj 2.311005 0 Td 40.470494 Tz (in ) Tj 0.65311 0 Td 44.37799 Tz (expression ) Tj 2.830144 0 Td 39.633174 Tz (level ) Tj 1.373206 0 Td 50.239234 Tz (were ) Tj 1.389952 0 Td 42.145136 Tz (calculated ) Tj 2.696172 0 Td 40.470494 Tz (as ) Tj 1.758373 0 Td 39.836161 Tz (precipitate ) Tj 2.84689 0 Td 53.030303 Tz (was ) Tj 1.205742 0 Td 43.416622 Tz (dissolved ) Tj 2.578947 0 Td 39.07496 Tz (in ) Tj 0.703349 0 Td 48.8437 Tz (40 ) Tj 0.803828 0 Td 54.425837 Tz (ml ) Tj 0.88756 0 Td 54.704944 Tz (0.15M ) Tj 1.858852 0 Td 53.72807 Tz (NaCl ) Tj 1.373206 0 Td 11.164274 Tz (. ) Tj 0.334928 0 Td 44.967216 Tz (Extensive ) Tj 58.163265 0 0 58.163265 0 173.604603 Tm 5.53614 0 Td 52.653509 Tz (compared ) Tj 2.733684 0 Td 38.684211 Tz (to ) Tj 0.739298 0 Td 48.71345 Tz (0 ) Tj 0.515789 0 Td 46.421053 Tz (hours ) Tj 1.650526 0 Td 48.71345 Tz (of ) Tj 0.773684 0 Td 42.200957 Tz (inoculation ) Tj 2.854035 0 Td 28.654971 Tz (. ) Tj 58.571429 0 0 58.571429 0 173.063274 Tm 22.143902 0 Td 39.837398 Tz (dialysis ) Tj 2.270732 0 Td 54.065041 Tz (was ) Tj 1.34878 0 Td 50.50813 Tz (done ) Tj 1.570732 0 Td 42.682927 Tz (against ) Tj 2.15122 0 Td 55.203252 Tz (0.15M ) Tj 1.997561 0 Td 55.487805 Tz (NaCl ) Tj 1.690244 0 Td 45.528455 Tz (using ) Tj 1.741463 0 Td 42.682927 Tz (a ) Tj 0.614634 0 Td 39.837398 Tz (dialysis ) Tj 34.285714 0 0 34.285714 0 1299 Tm 36.195833 0 Td 72.916667 Tz (40 ) Tj 34.285714 0 0 34.285714 0 674 Tm 36.225 0 Td 68.055556 Tz (55 ) Tj 31.428571 0 0 31.428571 0 468 Tm 39.581818 0 Td 68.939394 Tz (60 ) Tj 32.857143 0 0 32.857143 0 450 Tm 20.573913 0 Td 77.536232 Tz (reverse ) Tj ET Q endstream endobj 195 0 obj << /Length 1 >> stream q endstream endobj 196 0 obj << /Length 59152 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 34.285714 0 0 34.285714 0 2339 Tm 36.283333 0 Td 63.194444 Tz (15 ) Tj 31.428571 0 0 31.428571 0 2132 Tm 39.55 0 Td 71.590909 Tz (20 ) Tj 31.428571 0 0 31.428571 0 1717 Tm 39.55 0 Td 71.590909 Tz (30 ) Tj 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.525 0 Td 74.537037 Tz (27 ) Tj 48.571429 0 0 48.571429 0 2973 Tm 35.432353 0 Td 78.921569 Tz (28 ) Tj 52.932331 0 0 52.932331 0 2916.006588 Tm 6.083239 0 Td 49.854009 Tz (tubing ) Tj 2.021449 0 Td 53.527462 Tz (of ) Tj 0.793466 0 Td 47.230114 Tz (cutoff ) Tj 1.832528 0 Td 50.378788 Tz (value ) Tj 1.75696 0 Td 49.32923 Tz (6-8 ) Tj 1.114631 0 Td 52.740294 Tz (kDaltons ) Tj 2.607102 0 Td 12.594697 Tz (. ) Tj 0.321165 0 Td 59.824811 Tz (The ) Tj 1.303551 0 Td 46.180556 Tz (dialysate ) Tj 2.701562 0 Td 59.824811 Tz (was ) Tj 1.303551 0 Td 51.165956 Tz (then ) Tj 2.663778 0 Td 39.358428 Tz (3. ) Tj 0.755682 0 Td 65.672348 Tz (TILLING ) Tj 3.022727 0 Td 57.305871 Tz (Based ) Tj 1.926989 0 Td 48.489583 Tz (Validation ) Tj 3.154972 0 Td 53.527462 Tz (of ) Tj 0.812358 0 Td 47.230114 Tz (the ) Tj 1.114631 0 Td 52.477904 Tz (Candidate ) Tj 3.098295 0 Td 61.399148 Tz (Gene ) Tj 59.785714 0 0 59.785714 0 2874.49279 Tm 5.419355 0 Td 39.824771 Tz (further ) Tj 1.873357 0 Td 40.422143 Tz (purified ) Tj 2.14098 0 Td 47.391477 Tz (by ) Tj 0.802867 0 Td 36.240542 Tz (affinity ) Tj 1.940263 0 Td 47.988849 Tz (chromatography ) Tj 4.031063 0 Td 27.87734 Tz (. ) Tj 0.384707 0 Td 40.621266 Tz (Briefly ) Tj 1.655914 0 Td 27.87734 Tz (, ) Tj 0.384707 0 Td 44.603744 Tz (a ) Tj 0.551971 0 Td 41.81601 Tz (chro- ) Tj 3.127838 0 Td 48.320722 Tz (For ) Tj 1.003584 0 Td 41.81601 Tz (validation ) Tj 2.676225 0 Td 45.997611 Tz (of ) Tj 0.635603 0 Td 42.745254 Tz (the ) Tj 0.936679 0 Td 43.984247 Tz (candidate ) Tj 2.542413 0 Td 48.785344 Tz (gene ) Tj 1.187575 0 Td 19.514138 Tz (, ) Tj 0.284349 0 Td 41.81601 Tz (the ) Tj 0.903226 0 Td 46.694544 Tz (powerful ) Tj 2.408602 0 Td 43.010753 Tz (reverse ) Tj 62.142857 0 0 62.142857 0 2831.559194 Tm 5.181609 0 Td 47.739464 Tz (matography ) Tj 3.057471 0 Td 49.616858 Tz (column ) Tj 1.931034 0 Td 50.957854 Tz (was ) Tj 1.110345 0 Td 48.275862 Tz (20 ) Tj 0.611494 0 Td 77.777778 Tz (% ) Tj 0.65977 0 Td 33.971903 Tz (filled ) Tj 1.367816 0 Td 44.923372 Tz (with ) Tj 1.23908 0 Td 37.994891 Tz (chitin ) Tj 1.512644 0 Td 50.957854 Tz (powder ) Tj 1.737931 0 Td 26.819923 Tz (, ) Tj 0.370115 0 Td 48.275862 Tz (and ) Tj 2.091954 0 Td 40.229885 Tz (genetics ) Tj 2.172414 0 Td 43.209877 Tz (technique ) Tj 2.574713 0 Td 45.59387 Tz (of ) Tj 0.708046 0 Td 56.321839 Tz (TILLING ) Tj 2.590805 0 Td 50.063857 Tz (was ) Tj 1.142529 0 Td 46.264368 Tz (used ) Tj 1.158621 0 Td 10.727969 Tz (. ) Tj 0.289655 0 Td 72.413793 Tz (A ) Tj 0.627586 0 Td 34.8659 Tz (total ) Tj 1.303448 0 Td 44.252874 Tz (of ) Tj 0.708046 0 Td 38.084291 Tz (forty ) Tj 60 0 0 60 0 2791.160593 Tm 5.383333 0 Td 40.384615 Tz (equilibriated ) Tj 3.283333 0 Td 45.833333 Tz (with ) Tj 1.266667 0 Td 53.888889 Tz (0.15M ) Tj 1.766667 0 Td 53.472222 Tz (NaCl ) Tj 1.366667 0 Td 11.111111 Tz (. ) Tj 0.25 0 Td 51.851852 Tz (The ) Tj 1.116667 0 Td 40.432099 Tz (dialysate ) Tj 2.333333 0 Td 52.777778 Tz (was ) Tj 1.133333 0 Td 43.253968 Tz (applied ) Tj 1.95 0 Td 38.888889 Tz (to ) Tj 1.75 0 Td 46.428571 Tz (mutants ) Tj 2.133333 0 Td 50 Tz (were ) Tj 1.383333 0 Td 39.166667 Tz (identified ) Tj 2.516667 0 Td 37.777778 Tz (after ) Tj 1.316667 0 Td 43.209877 Tz (screening ) Tj 2.516667 0 Td 32.407407 Tz (all ) Tj 0.766667 0 Td 41.666667 Tz (the ) Tj 0.916667 0 Td 41.203704 Tz (plants ) Tj 1.45 0 Td 27.777778 Tz (. ) Tj 0.383333 0 Td 50 Tz (Out ) Tj 1.083333 0 Td 47.222222 Tz (of ) Tj 58.571429 0 0 58.571429 0 2748.264879 Tm 5.497561 0 Td 42.682927 Tz (the ) Tj 0.956098 0 Td 53.116531 Tz (column ) Tj 2.082927 0 Td 50.271003 Tz (and ) Tj 1.058537 0 Td 42.682927 Tz (the ) Tj 0.956098 0 Td 53.116531 Tz (column ) Tj 2.065854 0 Td 54.065041 Tz (was ) Tj 1.143902 0 Td 53.590786 Tz (washed ) Tj 2.1 0 Td 42.682927 Tz (0.01 ) Tj 1.263415 0 Td 40.54878 Tz (Tris ) Tj 1.126829 0 Td 19.918699 Tz (- ) Tj 0.187805 0 Td 39.837398 Tz (Cl ) Tj 0.64878 0 Td 64.02439 Tz (pH ) Tj 0.973171 0 Td 40.785908 Tz (8.5 ) Tj 1.297561 0 Td 31.300813 Tz (5 ) Tj 0.785366 0 Td 51.219512 Tz (40 ) Tj 0.904878 0 Td 46.341463 Tz (mutants ) Tj 2.031707 0 Td 22.764228 Tz (, ) Tj 0.460976 0 Td 38.211382 Tz (fifteen ) Tj 1.895122 0 Td 51.219512 Tz (were ) Tj 1.536585 0 Td 49.512195 Tz (found ) Tj 1.758537 0 Td 39.837398 Tz (to ) Tj 0.785366 0 Td 49.796748 Tz (be ) Tj 0.921951 0 Td 40.785908 Tz (silent ) Tj 1.314634 0 Td 25.609756 Tz (, ) Tj 0.478049 0 Td 46.95122 Tz (twelve ) Tj 1.980488 0 Td 51.930894 Tz (were ) Tj 58.896104 0 0 58.896104 0 2710.080235 Tm 5.484234 0 Td 44.145535 Tz (containing ) Tj 2.954355 0 Td 67.916207 Tz (1M ) Tj 1.035722 0 Td 54.474458 Tz (NaCl ) Tj 1.545094 0 Td 39.617788 Tz (to ) Tj 0.71312 0 Td 52.823717 Tz (remove ) Tj 2.122381 0 Td 52.958471 Tz (unbound ) Tj 2.444983 0 Td 42.093899 Tz (proteins ) Tj 2.258214 0 Td 38.485851 Tz (until ) Tj 1.392282 0 Td 42.44763 Tz (the ) Tj 2.054465 0 Td 49.050594 Tz (mis ) Tj 0.950827 0 Td 25.468578 Tz (- ) Tj 0.203749 0 Td 44.711503 Tz (sense ) Tj 1.392282 0 Td 14.14921 Tz (, ) Tj 0.373539 0 Td 51.880436 Tz (two ) Tj 1.222492 0 Td 50.937155 Tz (were ) Tj 1.511136 0 Td 40.325248 Tz (intronic ) Tj 2.224256 0 Td 45.906325 Tz (mutations ) Tj 2.767585 0 Td 45.277472 Tz (near ) Tj 1.358324 0 Td 55.889379 Tz (Exon ) Tj 1.61301 0 Td 45.277472 Tz (2 ) Tj 0.322602 0 Td 14.14921 Tz (, ) Tj 0.407497 0 Td 49.993875 Tz (and ) Tj 48.012422 0 0 48.012422 0 2674.016129 Tm 6.727426 0 Td 90.25442 Tz (OD ) Tj 1.374644 0 Td 63.640937 Tz (280 ) Tj 1.4163 0 Td 57.971108 Tz (absorbance ) Tj 3.74903 0 Td 65.955153 Tz (was ) Tj 1.478784 0 Td 59.012505 Tz (lower ) Tj 2.02031 0 Td 55.541182 Tz (than ) Tj 1.603752 0 Td 53.80552 Tz (0.05 ) Tj 1.4163 0 Td 13.885295 Tz (. ) Tj 0.374903 0 Td 65.955153 Tz (The ) Tj 1.478784 0 Td 64.219491 Tz (column ) Tj 2.561837 0 Td 65.955153 Tz (was ) Tj 2.770116 0 Td 62.483829 Tz (two ) Tj 1.437128 0 Td 62.483829 Tz (were ) Tj 1.791203 0 Td 65.955153 Tz (non ) Tj 1.208021 0 Td 31.241915 Tz (- ) Tj 0.270763 0 Td 54.152652 Tz (sense ) Tj 1.916171 0 Td 57.083992 Tz (mutations ) Tj 3.061708 0 Td 27.770591 Tz (. ) Tj 0.479043 0 Td 62.483829 Tz (Nine ) Tj 1.791203 0 Td 58.020699 Tz (mutants ) Tj 2.770116 0 Td 56.929711 Tz (could ) Tj 1.978655 0 Td 54.384074 Tz (not ) Tj 1.270505 0 Td 60.748167 Tz (be ) Tj 60.928571 0 0 60.928571 0 2629.186256 Tm 5.30129 0 Td 43.767097 Tz (again ) Tj 1.47714 0 Td 51.51752 Tz (washed ) Tj 2.002345 0 Td 44.314185 Tz (twice ) Tj 1.509965 0 Td 45.134818 Tz (with ) Tj 1.263775 0 Td 41.031653 Tz (0.01 ) Tj 1.23095 0 Td 41.031653 Tz (Tris ) Tj 1.066823 0 Td 19.148105 Tz (- ) Tj 0.114889 0 Td 43.767097 Tz (Cl ) Tj 0.722157 0 Td 61.547479 Tz (pH ) Tj 0.951934 0 Td 38.296209 Tz (8.5 ) Tj 0.902696 0 Td 44.157874 Tz (without ) Tj 2.03517 0 Td 53.341149 Tz (NaCl ) Tj 1.345838 0 Td 10.941774 Tz (. ) Tj 1.378664 0 Td 46.806478 Tz (sequenced ) Tj 2.921454 0 Td 40.575746 Tz (successfully ) Tj 2.888628 0 Td 27.354435 Tz (. ) Tj 0.574443 0 Td 57.444314 Tz (Two ) Tj 1.460727 0 Td 45.01048 Tz (independent ) Tj 3.348183 0 Td 45.720985 Tz (mutants ) Tj 2.314185 0 Td 49.921844 Tz (were ) Tj 58.819876 0 0 58.819876 0 2588.676817 Tm 5.491341 0 Td 51.003168 Tz (To ) Tj 0.867054 0 Td 40.235832 Tz (elute ) Tj 1.428089 0 Td 42.50264 Tz (the ) Tj 0.986061 0 Td 39.669131 Tz (protein ) Tj 1.76811 0 Td 28.335093 Tz (, ) Tj 0.47603 0 Td 66.587469 Tz (1M ) Tj 1.037064 0 Td 42.907427 Tz (Glacial ) Tj 2.040127 0 Td 40.141382 Tz (acetic ) Tj 1.700106 0 Td 43.211017 Tz (acid ) Tj 1.241077 0 Td 53.836677 Tz (was ) Tj 1.207075 0 Td 48.169659 Tz (used ) Tj 1.207075 0 Td 11.334037 Tz (. ) Tj 0.32302 0 Td 53.836677 Tz (The ) Tj 2.278141 0 Td 39.38578 Tz (identified ) Tj 2.73717 0 Td 47.225155 Tz (having ) Tj 2.074129 0 Td 28.335093 Tz (G ) Tj 0.578036 0 Td 19.834565 Tz (> ) Tj 0.374023 0 Td 45.336149 Tz (A ) Tj 0.64604 0 Td 39.669131 Tz (transition ) Tj 2.41415 0 Td 11.334037 Tz (, ) Tj 0.47603 0 Td 43.717001 Tz (leading ) Tj 2.329145 0 Td 44.486096 Tz (Tryptophan ) Tj 3.196199 0 Td 26.918339 Tz (to ) Tj 61.428571 0 0 61.428571 0 2547.881356 Tm 5.25814 0 Td 39.793282 Tz (eluate ) Tj 1.595349 0 Td 51.550388 Tz (was ) Tj 1.123256 0 Td 42.054264 Tz (dialysed ) Tj 2.197674 0 Td 43.410853 Tz (again ) Tj 1.465116 0 Td 43.410853 Tz (using ) Tj 1.497674 0 Td 42.054264 Tz (0.15 ) Tj 1.22093 0 Td 86.821705 Tz (M ) Tj 0.683721 0 Td 52.906977 Tz (NaCl ) Tj 1.448837 0 Td 37.984496 Tz (to ) Tj 0.634884 0 Td 50.645995 Tz (remove ) Tj 2.002326 0 Td 40.697674 Tz (the ) Tj 1.155814 0 Td 33.914729 Tz (10 ) Tj 0.830233 0 Td 47.028424 Tz (change ) Tj 1.839535 0 Td 36.627907 Tz (to ) Tj 0.634884 0 Td 40.01938 Tz (stop ) Tj 1.139535 0 Td 48.837209 Tz (codon ) Tj 1.611628 0 Td 35.271318 Tz (at ) Tj 0.553488 0 Td 40.39621 Tz (positions ) Tj 2.344186 0 Td 47.932817 Tz (233 ) Tj 1.04186 0 Td 48.837209 Tz (and ) Tj 1.025581 0 Td 45.219638 Tz (361 ) Tj 1.05814 0 Td 43.410853 Tz (of ) Tj 0.683721 0 Td 38.888889 Tz (the ) Tj 0.797674 0 Td 41.085271 Tz (protein ) Tj 1.774419 0 Td 10.852713 Tz (. ) Tj 58.571429 0 0 58.571429 0 2506.163079 Tm 5.514634 0 Td 42.682927 Tz (eluants ) Tj 1.809756 0 Td 19.918699 Tz (. ) Tj 0.426829 0 Td 54.065041 Tz (The ) Tj 1.263415 0 Td 41.615854 Tz (purified ) Tj 2.270732 0 Td 43.495935 Tz (protein ) Tj 2.1 0 Td 53.116531 Tz (was ) Tj 1.280488 0 Td 45.528455 Tz (then ) Tj 1.382927 0 Td 49.085366 Tz (used ) Tj 1.45122 0 Td 38.414634 Tz (to ) Tj 0.802439 0 Td 48.943089 Tz (check ) Tj 1.758537 0 Td 42.682927 Tz (the ) Tj 2.082927 0 Td 55.96206 Tz (FIG ) Tj 1.058537 0 Td 11.382114 Tz (. ) Tj 0.290244 0 Td 42.682927 Tz (3 ) Tj 0.512195 0 Td 51.219512 Tz (shows ) Tj 1.72439 0 Td 42.682927 Tz (the ) Tj 0.956098 0 Td 42.276423 Tz (Clustal ) Tj 1.980488 0 Td 60.325203 Tz (Omega ) Tj 1.997561 0 Td 47.109304 Tz (alignment ) Tj 2.731707 0 Td 46.95122 Tz (of ) Tj 0.665854 0 Td 43.631436 Tz (the ) Tj 0.973171 0 Td 44.896116 Tz (candidate ) Tj 63.785714 0 0 63.785714 0 2466.0013 Tm 5.06383 0 Td 38.932437 Tz (antifungal ) Tj 2.586786 0 Td 36.254199 Tz (activity ) Tj 1.959686 0 Td 48.338932 Tz (on ) Tj 0.799552 0 Td 39.193729 Tz (a ) Tj 0.454647 0 Td 40.064701 Tz (potato ) Tj 1.693169 0 Td 40.826801 Tz (dextrose ) Tj 2.194849 0 Td 41.806644 Tz (agar ) Tj 1.191489 0 Td 37.62598 Tz (plate ) Tj 1.348264 0 Td 43.766331 Tz (with ) Tj 1.269877 0 Td 45.726017 Tz (48 ) Tj 1.755879 0 Td 45.072788 Tz (gene ) Tj 1.316909 0 Td 42.96794 Tz (sequences ) Tj 2.555431 0 Td 44.41956 Tz (of ) Tj 0.658455 0 Td 39.193729 Tz (the ) Tj 0.924972 0 Td 43.299739 Tz (mutants ) Tj 2.053751 0 Td 37.887271 Tz (as ) Tj 0.68981 0 Td 47.032475 Tz (compared ) Tj 2.477044 0 Td 43.113102 Tz (with ) Tj 1.238522 0 Td 39.193729 Tz (the ) Tj 0.972004 0 Td 49.64539 Tz (wild ) Tj 60.714286 0 0 60.714286 0 2423.578222 Tm 5.303529 0 Td 45.019608 Tz (hours ) Tj 1.68 0 Td 46.666667 Tz (of ) Tj 0.807059 0 Td 43.006536 Tz (fungal ) Tj 1.877647 0 Td 41.675579 Tz (inoculation ) Tj 3.063529 0 Td 35.686275 Tz (at ) Tj 0.741176 0 Td 48.039216 Tz (72 ) Tj 0.625882 0 Td 30.196078 Tz ( ) Tj 0.527059 0 Td 42.54902 Tz (C. ) Tj 0.84 0 Td 44.470588 Tz (using ) Tj 1.647059 0 Td 52.156863 Tz (~ ) Tj 0.395294 0 Td 45.294118 Tz (10 ) Tj 0.757647 0 Td 50.326797 Tz (macro- ) Tj 3.08 0 Td 45.294118 Tz (type ) Tj 1.021176 0 Td 24.705882 Tz (. ) Tj 0.494118 0 Td 53.986928 Tz (FIG ) Tj 1.021176 0 Td 10.980392 Tz (. ) Tj 0.411765 0 Td 43.921569 Tz (4 ) Tj 0.609412 0 Td 49.411765 Tz (shows ) Tj 1.795294 0 Td 41.176471 Tz (the ) Tj 1.054118 0 Td 40.784314 Tz (Clustal ) Tj 2.025882 0 Td 58.745098 Tz (Omega ) Tj 2.075294 0 Td 45.141612 Tz (alignment ) Tj 2.750588 0 Td 46.666667 Tz (of ) Tj 0.774118 0 Td 42.091503 Tz (the ) Tj 60.300752 0 0 60.300752 0 2385.680606 Tm 5.356484 0 Td 43.038238 Tz (conidia ) Tj 1.990025 0 Td 46.9867 Tz (of ) Tj 0.646758 0 Td 49.750623 Tz (Fusarium ) Tj 2.570449 0 Td 51.006952 Tz (graminearum ) Tj 3.598628 0 Td 37.312968 Tz (strain ) Tj 1.525686 0 Td 44.775561 Tz (3639. ) Tj 1.542269 0 Td 44.222776 Tz (This ) Tj 1.260349 0 Td 42.643392 Tz (experi- ) Tj 3.001621 0 Td 45.073214 Tz (corresponding ) Tj 3.664963 0 Td 41.853699 Tz (protein ) Tj 1.907107 0 Td 45.604738 Tz (of ) Tj 0.613591 0 Td 42.380161 Tz (the ) Tj 0.895511 0 Td 46.197007 Tz (mutants ) Tj 2.10611 0 Td 49.750623 Tz (and ) Tj 1.011596 0 Td 46.295719 Tz (wild ) Tj 1.227182 0 Td 44.913757 Tz (type ) Tj 1.07793 0 Td 24.875312 Tz (. ) Tj 0.298504 0 Td 49.750623 Tz (Both ) Tj 1.3101 0 Td 41.458853 Tz (the ) Tj 60.785714 0 0 60.785714 0 2342.947674 Tm 5.297297 0 Td 51.410106 Tz (ment ) Tj 1.447709 0 Td 51.181616 Tz (was ) Tj 1.168038 0 Td 48.668233 Tz (done ) Tj 1.414806 0 Td 38.386212 Tz (in ) Tj 0.674501 0 Td 37.700744 Tz (five ) Tj 1.118684 0 Td 39.528659 Tz (replications ) Tj 2.862515 0 Td 27.418723 Tz (. ) Tj 0.39483 0 Td 47.982765 Tz (Four ) Tj 1.381904 0 Td 34.860948 Tz (sterile ) Tj 1.694477 0 Td 31.98851 Tz (filter ) Tj 1.365452 0 Td 41.128085 Tz (disks ) Tj 2.500588 0 Td 45.828437 Tz (mutants ) Tj 2.188014 0 Td 49.353702 Tz (were ) Tj 1.431257 0 Td 40.214127 Tz (tested ) Tj 1.694477 0 Td 39.30017 Tz (for ) Tj 0.93772 0 Td 37.837838 Tz (their ) Tj 1.365452 0 Td 44.898159 Tz (response ) Tj 2.40188 0 Td 37.015276 Tz (to ) Tj 0.707403 0 Td 35.64434 Tz (F. ) Tj 0.674501 0 Td 50.600007 Tz (graminearum ) Tj 55.2 0 0 55.2 0 2303.658339 Tm 5.833333 0 Td 54.347826 Tz (were ) Tj 1.467391 0 Td 49.31562 Tz (placed ) Tj 1.938406 0 Td 55.857488 Tz (on ) Tj 0.815217 0 Td 45.289855 Tz (the ) Tj 0.978261 0 Td 43.478261 Tz (plate ) Tj 1.485507 0 Td 37.741546 Tz (at ) Tj 0.634058 0 Td 54.347826 Tz (-3 ) Tj 0.869565 0 Td 66.425121 Tz (cm ) Tj 0.978261 0 Td 45.667271 Tz (distance ) Tj 2.355072 0 Td 54.347826 Tz (from ) Tj 1.449275 0 Td 46.296296 Tz (the ) Tj 0.978261 0 Td 50.89717 Tz (mycelia ) Tj 2.210145 0 Td 12.077295 Tz (. ) Tj 1.503623 0 Td 43.276973 Tz (infection ) Tj 2.40942 0 Td 21.135266 Tz (. ) Tj 0.307971 0 Td 31.702899 Tz (It ) Tj 0.525362 0 Td 57.36715 Tz (was ) Tj 1.213768 0 Td 52.536232 Tz (found ) Tj 1.702899 0 Td 42.270531 Tz (that ) Tj 1.15942 0 Td 45.289855 Tz (the ) Tj 0.960145 0 Td 50.465839 Tz (mutants ) Tj 2.282609 0 Td 55.354267 Tz (had ) Tj 1.141304 0 Td 42.270531 Tz (loss ) Tj 1.195652 0 Td 51.328502 Tz (of ) Tj 0.688406 0 Td 44.384058 Tz (resistance ) Tj 60.434783 0 0 60.434783 0 2260.943276 Tm 5.344604 0 Td 45.043965 Tz (Eighty ) Tj 1.770504 0 Td 40.364072 Tz (microliters ) Tj 2.829496 0 Td 46.882494 Tz (of ) Tj 0.645324 0 Td 41.366906 Tz (the ) Tj 0.893525 0 Td 41.97975 Tz (extracted ) Tj 2.399281 0 Td 41.760877 Tz (protein ) Tj 1.886331 0 Td 51.478817 Tz (was ) Tj 1.108633 0 Td 43.336759 Tz (applied ) Tj 1.935971 0 Td 38.609113 Tz (to ) Tj 0.628777 0 Td 41.366906 Tz (the ) Tj 2.002158 0 Td 37.230216 Tz (to ) Tj 0.711511 0 Td 64.348521 Tz (FHB ) Tj 1.406475 0 Td 50.743405 Tz (owing ) Tj 1.753957 0 Td 37.230216 Tz (to ) Tj 0.694964 0 Td 41.366906 Tz (the ) Tj 0.959712 0 Td 52.398082 Tz (non ) Tj 0.959712 0 Td 24.820144 Tz (- ) Tj 0.215108 0 Td 43.021583 Tz (sense ) Tj 1.522302 0 Td 45.848321 Tz (mutation ) Tj 2.432374 0 Td 38.609113 Tz (in ) Tj 0.678417 0 Td 40.677458 Tz (them ) Tj 1.207914 0 Td 24.820144 Tz (, ) Tj 0.397122 0 Td 45.306612 Tz (proving ) Tj 60.559006 0 0 60.559006 0 2221.8 Tm 5.333641 0 Td 32.108262 Tz (filter ) Tj 1.519179 0 Td 41.282051 Tz (disks ) Tj 1.634769 0 Td 44.584615 Tz (along ) Tj 1.717333 0 Td 45.410256 Tz (with ) Tj 1.453128 0 Td 40.25 Tz (positive ) Tj 2.328308 0 Td 40.495726 Tz (control ) Tj 2.113641 0 Td 27.521368 Tz (\( ) Tj 0.198154 0 Td 53.391453 Tz (0.15M ) Tj 1.981538 0 Td 44.42735 Tz (glucose ) Tj 3.120923 0 Td 38.529915 Tz (that ) Tj 1.155897 0 Td 44.951567 Tz (our ) Tj 1.023795 0 Td 43.422602 Tz (candidate ) Tj 2.576 0 Td 47.474359 Tz (gene ) Tj 1.370564 0 Td 30.273504 Tz (is ) Tj 0.594462 0 Td 41.282051 Tz (the ) Tj 0.974256 0 Td 49.538462 Tz (Fhb1 ) Tj 1.486154 0 Td 47.474359 Tz (gene ) Tj 1.387077 0 Td 27.521368 Tz (\( ) Tj 0.181641 0 Td 55.042735 Tz (FIG ) Tj 1.040308 0 Td 11.008547 Tz (. ) Tj 0.313744 0 Td 44.034188 Tz (5 ) Tj 0.313744 0 Td 27.521368 Tz (\) ) Tj 0.247692 0 Td 11.008547 Tz (. ) Tj 58.721805 0 0 58.721805 0 2181.774532 Tm 5.517542 0 Td 40.090162 Tz (solution ) Tj 2.094622 0 Td 28.382416 Tz (\) ) Tj 0.119206 0 Td 28.382416 Tz (, ) Tj 0.30653 0 Td 59.603073 Tz (mock ) Tj 1.566709 0 Td 41.762697 Tz (control ) Tj 1.941357 0 Td 28.382416 Tz (\( ) Tj 0.204353 0 Td 55.061886 Tz (0.15M ) Tj 1.788092 0 Td 55.345711 Tz (NaCl ) Tj 1.515621 0 Td 40.799723 Tz (solution ) Tj 2.128681 0 Td 28.382416 Tz (\) ) Tj 0.051088 0 Td 28.382416 Tz (, ) Tj 0.357618 0 Td 50.142268 Tz (and ) Tj 1.038796 0 Td 44.702305 Tz (negative ) Tj 3.439949 0 Td 35.47802 Tz (4. ) Tj 0.63009 0 Td 45.411865 Tz (Antifungal ) Tj 2.946095 0 Td 42.928404 Tz (Activity ) Tj 2.316005 0 Td 48.250107 Tz (of ) Tj 0.749296 0 Td 49.669227 Tz (Fhb1 ) Tj 1.515621 0 Td 42.979087 Tz (Protein ) Tj 57.142857 0 0 57.142857 0 2140.811536 Tm 5.6525 0 Td 43.333333 Tz (control ) Tj 2.0475 0 Td 29.166667 Tz (\( ) Tj 0.21 0 Td 39.861111 Tz (0.1 ) Tj 0.805 0 Td 84.583333 Tz (% ) Tj 0.735 0 Td 45.046296 Tz (fungicide ) Tj 2.6425 0 Td 45 Tz (Prosaro ) Tj 2.0825 0 Td 29.166667 Tz (\) ) Tj 0.105 0 Td 29.166667 Tz (. ) Tj 0.315 0 Td 46.666667 Tz (After ) Tj 1.575 0 Td 51.041667 Tz (72 ) Tj 0.8225 0 Td 46.666667 Tz (hours ) Tj 1.435 0 Td 26.25 Tz (, ) Tj 0.3675 0 Td 51.041667 Tz (growth ) Tj 2.03 0 Td 49.583333 Tz (of ) Tj 2.52 0 Td 58.916667 Tz (Owing ) Tj 2.1525 0 Td 39.375 Tz (to ) Tj 0.8925 0 Td 43.75 Tz (the ) Tj 1.1725 0 Td 48.125 Tz (well ) Tj 1.2425 0 Td 20.416667 Tz (- ) Tj 0.1225 0 Td 58.916667 Tz (known ) Tj 2.17 0 Td 37.916667 Tz (affinity ) Tj 2.2225 0 Td 49.583333 Tz (of ) Tj 0.9275 0 Td 39.583333 Tz (lectins ) Tj 2.0825 0 Td 48.75 Tz (towards ) Tj 60 0 0 60 0 2100.146497 Tm 5.35 0 Td 47.222222 Tz (mycelia ) Tj 2.183333 0 Td 53.703704 Tz (was ) Tj 1.183333 0 Td 44.444444 Tz (recorded ) Tj 2.166667 0 Td 25 Tz (. ) Tj 61.428571 0 0 61.428571 0 2103.946903 Tm 21.113953 0 Td 34.366925 Tz (chitin ) Tj 1.367442 0 Td 24.418605 Tz (, ) Tj 0.35814 0 Td 37.984496 Tz (chitin ) Tj 1.562791 0 Td 48.449612 Tz (columns ) Tj 2.246512 0 Td 47.48062 Tz (have ) Tj 1.334884 0 Td 48.158915 Tz (been ) Tj 1.334884 0 Td 46.802326 Tz (used ) Tj 1.302326 0 Td 41.684285 Tz (extensively ) Tj 2.946512 0 Td 37.984496 Tz (to ) Tj 0.667442 0 Td 40.697674 Tz (purify ) Tj 62.857143 0 0 62.857143 0 2063.583763 Tm 20.634091 0 Td 35.984848 Tz (lectins ) Tj 1.765909 0 Td 49.05303 Tz (by ) Tj 0.827273 0 Td 41.287879 Tz (various ) Tj 1.988636 0 Td 45.833333 Tz (workers ) Tj 1.940909 0 Td 18.560606 Tz (. ) Tj 0.334091 0 Td 42.954545 Tz (Antifungal ) Tj 2.831818 0 Td 36.458333 Tz (activity ) Tj 2.020455 0 Td 43.75 Tz (of ) Tj 0.715909 0 Td 39.772727 Tz (the ) Tj 0.986364 0 Td 50.378788 Tz (iso ) Tj 57.857143 0 0 57.857143 0 2026.238095 Tm 11.908642 0 Td 53.909465 Tz (Example ) Tj 2.506173 0 Td 46.090535 Tz (7 ) Tj 62.857143 0 0 62.857143 0 2022.821561 Tm 20.634091 0 Td 39.772727 Tz (lated ) Tj 1.415909 0 Td 37.878788 Tz (protein ) Tj 1.813636 0 Td 49.494949 Tz (was ) Tj 1.145455 0 Td 40.384615 Tz (characterized ) Tj 3.340909 0 Td 42.954545 Tz (using ) Tj 1.495455 0 Td 38.181818 Tz (petri ) Tj 1.177273 0 Td 31.818182 Tz (- ) Tj 0.175 0 Td 39.109848 Tz (dish ) Tj 1.145455 0 Td 38.44697 Tz (cultures ) Tj 2.020455 0 Td 50.378788 Tz (of ) Tj 58.571429 0 0 58.571429 0 1992.131854 Tm 22.126829 0 Td 42.682927 Tz (the ) Tj 1.041463 0 Td 46.95122 Tz (fungus ) Tj 1.946341 0 Td 36.99187 Tz (F. ) Tj 0.717073 0 Td 50.443459 Tz (graminearum ) Tj 3.465854 0 Td 25.609756 Tz (. ) Tj 0.478049 0 Td 48.373984 Tz (Spread ) Tj 1.997561 0 Td 48.373984 Tz (of ) Tj 0.768293 0 Td 42.682927 Tz (the ) Tj 1.041463 0 Td 44.579946 Tz (fungal ) Tj 1.860976 0 Td 47.560976 Tz (mycelia ) Tj 45.714286 0 0 45.714286 0 1938 Tm 11.484375 0 Td 58.664773 Tz (Association ) Tj 4.178125 0 Td 55.729167 Tz (Studies ) Tj 2.66875 0 Td 60.15625 Tz (of ) Tj 0.91875 0 Td 54.6875 Tz (the ) Tj 1.290625 0 Td 71.09375 Tz (Gene ) Tj 58.571429 0 0 58.571429 0 1947.179234 Tm 22.126829 0 Td 54.065041 Tz (was ) Tj 1.143902 0 Td 41.971545 Tz (arrested ) Tj 2.168293 0 Td 52.642276 Tz (on ) Tj 0.785366 0 Td 50.271003 Tz (and ) Tj 1.041463 0 Td 46.239837 Tz (near ) Tj 1.263415 0 Td 33.197832 Tz (filter ) Tj 1.34878 0 Td 42.682927 Tz (disks ) Tj 1.434146 0 Td 47.662602 Tz (with ) Tj 1.280488 0 Td 42.682927 Tz (the ) Tj 0.939024 0 Td 41.260163 Tz (isolated ) Tj 2.117073 0 Td 43.089431 Tz (protein ) Tj 64.285714 0 0 64.285714 0 1908.063107 Tm 19.351111 0 Td 33.703704 Tz (25 ) Tj 0.824444 0 Td 45.802469 Tz (and ) Tj 1.011111 0 Td 38.888889 Tz (the ) Tj 0.902222 0 Td 40.329218 Tz (fungicide ) Tj 2.38 0 Td 40.740741 Tz (Prosaro ) Tj 1.788889 0 Td 18.148148 Tz (. ) Tj 0.217778 0 Td 47.962963 Tz (In ) Tj 0.871111 0 Td 37.268519 Tz (contrast ) Tj 1.804444 0 Td 33.703704 Tz (, ) Tj 0.233333 0 Td 39.753086 Tz (the ) Tj 0.917778 0 Td 41.157407 Tz (mycelial ) Tj 2.193333 0 Td 45.37037 Tz (growth ) Tj 64.107143 0 0 64.107143 0 1847.231183 Tm 5.631198 0 Td 44.196843 Tz (For ) Tj 1.029526 0 Td 39.233561 Tz (association ) Tj 2.823398 0 Td 48.282266 Tz (mapping ) Tj 2.261838 0 Td 38.997214 Tz (the ) Tj 0.967131 0 Td 46.146704 Tz (Fhbl ) Tj 1.435097 0 Td 44.846797 Tz (gene ) Tj 1.310306 0 Td 49.396472 Tz (was ) Tj 1.169916 0 Td 44.77458 Tz (sequenced ) Tj 64.285714 0 0 64.285714 0 1868.716755 Tm 20.16 0 Td 49.259259 Tz (was ) Tj 1.213333 0 Td 42.777778 Tz (un ) Tj 0.606667 0 Td 33.703704 Tz (- ) Tj 0.217778 0 Td 37.736626 Tz (inhibited ) Tj 2.364444 0 Td 46.666667 Tz (on ) Tj 0.871111 0 Td 54.444444 Tz (mock ) Tj 1.633333 0 Td 45.802469 Tz (and ) Tj 1.135556 0 Td 38.240741 Tz (positive ) Tj 2.162222 0 Td 38.240741 Tz (controls ) Tj 2.053333 0 Td 47.098765 Tz (having ) Tj 57.857143 0 0 57.857143 0 1835.623153 Tm 22.417284 0 Td 55.884774 Tz (0.15M ) Tj 1.866667 0 Td 56.17284 Tz (NaCl ) Tj 1.57284 0 Td 50.891632 Tz (and ) Tj 1.106173 0 Td 56.460905 Tz (0.15M ) Tj 1.883951 0 Td 46.502058 Tz (glucose ) Tj 2.004938 0 Td 14.403292 Tz (, ) Tj 0.293827 0 Td 42.729767 Tz (respectively ) Tj 3.041975 0 Td 28.806584 Tz (, ) Tj 0.432099 0 Td 51.028807 Tz (showing ) Tj 2.333333 0 Td 40.329218 Tz (that ) Tj 61.428571 0 0 61.428571 0 1801.93913 Tm 5.25814 0 Td 48.837209 Tz (from ) Tj 1.334884 0 Td 43.410853 Tz (41 ) Tj 0.732558 0 Td 37.984496 Tz (varieties ) Tj 2.295349 0 Td 42.054264 Tz (of ) Tj 0.553488 0 Td 51.007752 Tz (wheat ) Tj 1.644186 0 Td 48.837209 Tz (from ) Tj 1.334884 0 Td 48.837209 Tz (China ) Tj 1.4 0 Td 24.418605 Tz (, ) Tj 0.35814 0 Td 45.581395 Tz (Japan ) Tj 1.530233 0 Td 47.932817 Tz (and ) Tj 1.009302 0 Td 67.829457 Tz (USA ) Tj 1.334884 0 Td 45.445736 Tz (with ) Tj 57.44898 0 0 57.44898 0 1796.122208 Tm 22.559147 0 Td 43.516874 Tz (the ) Tj 1.026998 0 Td 42.066311 Tz (isolated ) Tj 2.228064 0 Td 43.93132 Tz (protein ) Tj 2.071403 0 Td 39.890468 Tz (inhibits ) Tj 2.158437 0 Td 51.253207 Tz (growth ) Tj 2.071403 0 Td 47.868561 Tz (of ) Tj 0.731083 0 Td 43.516874 Tz (the ) Tj 1.026998 0 Td 47.868561 Tz (fungus ) Tj 2.001776 0 Td 29.011249 Tz (\( ) Tj 0.208881 0 Td 57.055457 Tz (FIG ) Tj 1.079218 0 Td 11.6045 Tz (. ) Tj 0.365542 0 Td 29.011249 Tz (6 ) Tj 0.330728 0 Td 26.110124 Tz (\) ) Tj 0.191474 0 Td 26.110124 Tz (. ) Tj 61.714286 0 0 61.714286 0 1761.381026 Tm 5.217593 0 Td 55.092593 Tz (known ) Tj 1.814815 0 Td 63.014403 Tz (FHB ) Tj 1.328704 0 Td 39.496528 Tz (reaction ) Tj 1.944444 0 Td 21.604938 Tz (. ) Tj 0.30787 0 Td 51.311728 Tz (The ) Tj 1.101852 0 Td 43.209877 Tz (following ) Tj 2.511574 0 Td 44.560185 Tz (primer ) Tj 1.782407 0 Td 44.710219 Tz (sequences ) Tj 2.592593 0 Td 48.611111 Tz (were ) Tj 2.430556 0 Td 32.407407 Tz (5. ) Tj 0.583333 0 Td 43.455387 Tz (Association ) Tj 3.111111 0 Td 45.37037 Tz (Study ) Tj 1.587963 0 Td 45.910494 Tz (of ) Tj 0.712963 0 Td 47.935957 Tz (Fhb1 ) Tj 1.44213 0 Td 52.662037 Tz (Gene ) Tj 57.142857 0 0 57.142857 0 1725.436823 Tm 5.635 0 Td 50.3125 Tz (used ) Tj 1.3825 0 Td 41.805556 Tz (for ) Tj 0.945 0 Td 48.416667 Tz (sequencing ) Tj 3.0975 0 Td 40.509259 Tz (different ) Tj 2.345 0 Td 42 Tz (parts ) Tj 1.4525 0 Td 49.583333 Tz (of ) Tj 0.7 0 Td 43.75 Tz (the ) Tj 43.571429 0 0 43.571429 0 1727.578947 Tm 21.642623 0 Td 65.027322 Tz (gene ) Tj 1.629508 0 Td 30.601093 Tz (. ) Tj 58.461538 0 0 58.461538 0 1719.617312 Tm 17.686842 0 Td 54.879386 Tz (Fhb1 ) Tj 1.419737 0 Td 19.95614 Tz (- ) Tj 0.153947 0 Td 51.315789 Tz (Exon1 ) Tj 3.557895 0 Td 54.166667 Tz (The ) Tj 1.248684 0 Td 46.564327 Tz (haplotype ) Tj 2.822368 0 Td 47.039474 Tz (of ) Tj 0.786842 0 Td 51.315789 Tz (Fhbl ) Tj 1.590789 0 Td 49.177632 Tz (gene ) Tj 1.488158 0 Td 57.017544 Tz (among ) Tj 2.001316 0 Td 42.763158 Tz (a ) Tj 0.547368 0 Td 41.907895 Tz (collection ) Tj 2.805263 0 Td 47.039474 Tz (of ) Tj 0.803947 0 Td 44.188596 Tz (41 ) Tj 54.661654 0 0 54.661654 0 1682.039831 Tm 5.909078 0 Td 51.398441 Tz (forward ) Tj 2.579505 0 Td 50.817668 Tz (primer ) Tj 2.268501 0 Td 39.637781 Tz (\( ) Tj 0.347593 0 Td 30.490601 Tz (5 ) Tj 0.237827 0 Td 30.490601 Tz (' ) Tj 0.146355 0 Td 30.490601 Tz (- ) Tj 0.201238 0 Td 75.256346 Tz (CCCTTACTCTTCCAGCTTGAGA ) Tj 10.025309 0 Td 30.490601 Tz (- ) Tj 0.237827 0 Td 30.490601 Tz (3 ) Tj 0.201238 0 Td 30.490601 Tz (' ) Tj 1.573315 0 Td 47.260431 Tz (accessions ) Tj 3.018569 0 Td 62.200825 Tz (known ) Tj 2.01238 0 Td 44.719548 Tz (for ) Tj 0.933012 0 Td 42.077029 Tz (their ) Tj 1.408666 0 Td 54.120816 Tz (Fhbl ) Tj 1.536726 0 Td 52.215154 Tz (mediated ) Tj 2.652682 0 Td 44.821183 Tz (resistance ) Tj 2.835626 0 Td 42.686841 Tz (to ) Tj 0.695186 0 Td 71.144735 Tz (FHB ) Tj 60.788177 0 0 60.788177 0 1638.329218 Tm 5.313533 0 Td 27.417612 Tz (\( ) Tj 0.213857 0 Td 61.232667 Tz (SEQ ) Tj 1.661507 0 Td 52.093463 Tz (ID ) Tj 1.16799 0 Td 72.656672 Tz (NO ) Tj 0.937682 0 Td 10.967045 Tz (: ) Tj 0.197407 0 Td 42.497299 Tz (16 ) Tj 0.559319 0 Td 27.417612 Tz (\) ) Tj 0.197407 0 Td 27.417612 Tz (\) ) Tj 0.246759 0 Td 13.708806 Tz (; ) Tj 0.658023 0 Td 54.149784 Tz (Fhb1 ) Tj 1.365397 0 Td 21.93409 Tz (- ) Tj 0.082253 0 Td 51.545111 Tz (Exon1 ) Tj 2.171475 0 Td 41.909778 Tz (reverse ) Tj 2.303079 0 Td 45.69602 Tz (primer ) Tj 2.204376 0 Td 27.417612 Tz (\( ) Tj 0.213857 0 Td 34.728975 Tz (5'- ) Tj 1.826013 0 Td 49.351702 Tz (were ) Tj 1.332496 0 Td 44.416532 Tz (determined ) Tj 2.747245 0 Td 21.93409 Tz (. ) Tj 0.29611 0 Td 51.179543 Tz (The ) Tj 1.069287 0 Td 49.351702 Tz (Fhbl ) Tj 1.398298 0 Td 47.295381 Tz (gene ) Tj 1.266694 0 Td 51.179543 Tz (was ) Tj 1.102188 0 Td 47.158293 Tz (found ) Tj 1.529903 0 Td 38.384657 Tz (to ) Tj 0.608671 0 Td 47.980821 Tz (be ) Tj 0.707374 0 Td 41.909778 Tz (present ) Tj 1.924716 0 Td 32.901135 Tz (\( ) Tj 0.246759 0 Td 42.497299 Tz (no ) Tj 55.102041 0 0 55.102041 0 1598.928796 Tm 5.861852 0 Td 77.542088 Tz (GGAAAGAGGGACGTGCTTAAAT ) Tj 10.326296 0 Td 24.197531 Tz (- ) Tj 0.217778 0 Td 24.197531 Tz (3 ) Tj 0.181481 0 Td 24.197531 Tz (' ) Tj 0.435556 0 Td 30.246914 Tz (\( ) Tj 0.217778 0 Td 68.559671 Tz (SEQ ) Tj 1.488148 0 Td 57.469136 Tz (ID ) Tj 0.925556 0 Td 80.154321 Tz (NO ) Tj 1.034444 0 Td 12.098765 Tz (: ) Tj 0.217778 0 Td 46.882716 Tz (17 ) Tj 0.617037 0 Td 30.246914 Tz (\) ) Tj 0.217778 0 Td 30.246914 Tz (\) ) Tj 0.272222 0 Td 15.123457 Tz (; ) Tj 1.542593 0 Td 66.54321 Tz (SNP ) Tj 1.234074 0 Td 30.246914 Tz (\) ) Tj 0.381111 0 Td 43.858025 Tz (in ) Tj 0.707778 0 Td 35.288066 Tz (all ) Tj 0.852963 0 Td 51.419753 Tz (22 ) Tj 0.834815 0 Td 51.419753 Tz (of ) Tj 0.725926 0 Td 45.37037 Tz (the ) Tj 0.998148 0 Td 41.673525 Tz (resistant ) Tj 2.431852 0 Td 42.009602 Tz (varieties ) Tj 2.468148 0 Td 44.36214 Tz (tested ) Tj 1.796667 0 Td 30.246914 Tz (\( ) Tj 0.235926 0 Td 55.654321 Tz (Sumai ) Tj 1.887407 0 Td 45.37037 Tz (3 ) Tj 0.344815 0 Td 15.123457 Tz (, ) Tj 0.272222 0 Td 58.477366 Tz (Aso ) Tj 57.346939 0 0 57.346939 0 1562.955102 Tm 5.614947 0 Td 58.125741 Tz (Fhb1 ) Tj 1.37758 0 Td 31.969158 Tz (- ) Tj 0.209253 0 Td 55.800712 Tz (Exon2 ) Tj 1.743772 0 Td 31.969158 Tz (- ) Tj 0.139502 0 Td 42.431791 Tz (part1 ) Tj 3.417794 0 Td 48.991696 Tz (forward ) Tj 4.097865 0 Td 48.922499 Tz (primer ) Tj 50 0 0 50 0 1562.229167 Tm 23.46 0 Td 36.666667 Tz (\( ) Tj 0.18 0 Td 61.666667 Tz (5' ) Tj 60 0 0 60 0 1565.429836 Tm 21.633333 0 Td 39.814815 Tz (Zairai ) Tj 1.866667 0 Td 27.777778 Tz (II ) Tj 0.4 0 Td 16.666667 Tz (, ) Tj 0.5 0 Td 50 Tz (Nyubai ) Tj 1.866667 0 Td 16.666667 Tz (, ) Tj 0.5 0 Td 53.08642 Tz (Nobeokabouzukamugi ) Tj 5.6 0 Td 27.777778 Tz (, ) Tj 0.6 0 Td 50.757576 Tz (Huangcandou ) Tj 3.45 0 Td 27.777778 Tz (, ) Tj 59.74026 0 0 59.74026 0 1521.086344 Tm 5.406739 0 Td 69.873188 Tz (CGCACCCCTAAAACCCAAAATA ) Tj 9.390652 0 Td 19.528986 Tz (- ) Tj 0.267826 0 Td 19.528986 Tz (3 ) Tj 0.150652 0 Td 19.528986 Tz (' ) Tj 0.418478 0 Td 27.898551 Tz (\( ) Tj 0.20087 0 Td 63.236715 Tz (SEQ ) Tj 1.406087 0 Td 53.007246 Tz (ID ) Tj 0.887174 0 Td 73.931159 Tz (NO ) Tj 0.95413 0 Td 11.15942 Tz (: ) Tj 0.20087 0 Td 43.242754 Tz (18 ) Tj 0.56913 0 Td 27.898551 Tz (\) ) Tj 0.20087 0 Td 27.898551 Tz (\) ) Tj 0.251087 0 Td 13.949275 Tz (; ) Tj 1.406087 0 Td 50.471014 Tz (Haiyanzhong ) Tj 3.26413 0 Td 27.898551 Tz (, ) Tj 0.435217 0 Td 53.286232 Tz (Huoshaomai ) Tj 3.113478 0 Td 25.108696 Tz (, ) Tj 0.401739 0 Td 54.681159 Tz (Huang ) Tj 1.874783 0 Td 50.914855 Tz (Fang ) Tj 1.456304 0 Td 49.28744 Tz (Zhu ) Tj 1.004348 0 Td 25.108696 Tz (, ) Tj 0.334783 0 Td 53.007246 Tz (Baishanyue ) Tj 56 0 0 56 0 1480.293436 Tm 5.785714 0 Td 57.291667 Tz (Fhb1 ) Tj 1.428571 0 Td 29.761905 Tz (- ) Tj 0.196429 0 Td 54.166667 Tz (Exon2 ) Tj 1.732143 0 Td 29.761905 Tz (- ) Tj 0.160714 0 Td 42.261905 Tz (part1 ) Tj 57.222222 0 0 57.222222 0 1482.876652 Tm 14.627184 0 Td 48.543689 Tz (primer ) Tj 3.005825 0 Td 34.951456 Tz (\( ) Tj 0.192233 0 Td 34.951456 Tz (5 ) Tj 0.279612 0 Td 34.951456 Tz (' ) Tj 0.209709 0 Td 34.951456 Tz (- ) Tj 0.087379 0 Td 69.070735 Tz (CAACTG- ) Tj 4.246602 0 Td 54.174757 Tz (huang ) Tj 1.537864 0 Td 29.126214 Tz (, ) Tj 0.332039 0 Td 52.427184 Tz (Abura ) Tj 1.607767 0 Td 26.213592 Tz (, ) Tj 0.349515 0 Td 55.075022 Tz (NobeokaBozu ) Tj 3.739806 0 Td 26.213592 Tz (, ) Tj 0.314563 0 Td 48.349515 Tz (Tokai ) Tj 1.660194 0 Td 49.514563 Tz (66 ) Tj 0.646602 0 Td 14.563107 Tz (, ) Tj 0.314563 0 Td 45.145631 Tz (Shuilizhan ) Tj 2.726214 0 Td 26.213592 Tz (, ) Tj 0.471845 0 Td 56.31068 Tz (Sanshu ) Tj 58.742857 0 0 58.742857 0 1442.152062 Tm 5.498541 0 Td 68.980018 Tz (CATCTGTTCTGACACA ) Tj 6.860409 0 Td 19.860571 Tz (- ) Tj 0.221304 0 Td 19.860571 Tz (3 ) Tj 0.15321 0 Td 19.860571 Tz (' ) Tj 0.680934 0 Td 28.372244 Tz (\( ) Tj 0.20428 0 Td 64.310419 Tz (SEQ ) Tj 1.668288 0 Td 53.907263 Tz (ID ) Tj 1.140564 0 Td 75.186446 Tz (NO ) Tj 0.970331 0 Td 11.348898 Tz (: ) Tj 0.20428 0 Td 43.976978 Tz (19 ) Tj 0.578794 0 Td 28.372244 Tz (\) ) Tj 0.221304 0 Td 28.372244 Tz (\) ) Tj 0.238327 0 Td 14.186122 Tz (; ) Tj 0.629864 0 Td 49.367704 Tz (Fhb1- ) Tj 2.791829 0 Td 55.325875 Tz (komugi ) Tj 1.923638 0 Td 28.372244 Tz (, ) Tj 0.442607 0 Td 49.006603 Tz (Shinchunaga ) Tj 3.234436 0 Td 28.372244 Tz (, ) Tj 0.425584 0 Td 47.878161 Tz (Shanasui ) Tj 2.247082 0 Td 25.535019 Tz (, ) Tj 0.40856 0 Td 49.780391 Tz (Wangshuibai ) Tj 3.251459 0 Td 28.372244 Tz (, ) Tj 0.425584 0 Td 52.488651 Tz (Ning ) Tj 1.515078 0 Td 51.779345 Tz (7840 ) Tj 1.293774 0 Td 14.186122 Tz (, ) Tj 55.535714 0 0 55.535714 0 1404.436264 Tm 5.816077 0 Td 54.619507 Tz (Exon2 ) Tj 1.81865 0 Td 30.010718 Tz (- ) Tj 0.144051 0 Td 43.815648 Tz (part2 ) Tj 2.466881 0 Td 50.589496 Tz (forward ) Tj 3.151125 0 Td 50.518042 Tz (primer ) Tj 2.917042 0 Td 30.010718 Tz (\( ) Tj 0.25209 0 Td 30.010718 Tz (5 ) Tj 0.270096 0 Td 30.010718 Tz (' ) Tj 0.198071 0 Td 30.010718 Tz (- ) Tj 0.162058 0 Td 72.298548 Tz (ACATGACCAC- ) Tj 6.158199 0 Td 57.520543 Tz (Wannin ) Tj 2.304823 0 Td 48.017149 Tz (2 ) Tj 0.360129 0 Td 15.005359 Tz (, ) Tj 0.360129 0 Td 78.027867 Tz (WZHHS ) Tj 2.412862 0 Td 15.005359 Tz (, ) Tj 0.360129 0 Td 52.018578 Tz (Taiwan ) Tj 1.962701 0 Td 27.009646 Tz (, ) Tj 0.414148 0 Td 50.017864 Tz (701 ) Tj 1.242444 0 Td 60.39657 Tz (Chokwang ) Tj 2.971061 0 Td 30.010718 Tz (\) ) Tj 0.108039 0 Td 30.010718 Tz (. ) Tj 0.450161 0 Td 57.020364 Tz (Most ) Tj 1.620579 0 Td 49.517685 Tz (of ) Tj 0.75627 0 Td 45.016077 Tz (the ) Tj 55.714286 0 0 55.714286 0 1355 Tm 5.797436 0 Td 77.52849 Tz (CACAACAAACAA ) Tj 5.779487 0 Td 20.940171 Tz (- ) Tj 0.287179 0 Td 20.940171 Tz (3 ) Tj 0.14359 0 Td 20.940171 Tz (' ) Tj 0.538462 0 Td 29.91453 Tz (\( ) Tj 0.233333 0 Td 66.809117 Tz (SEQ ) Tj 1.633333 0 Td 55.34188 Tz (ID ) Tj 1.058974 0 Td 79.273504 Tz (NO ) Tj 1.023077 0 Td 11.965812 Tz (: ) Tj 0.161538 0 Td 52.350427 Tz (20 ) Tj 0.664103 0 Td 29.91453 Tz (\) ) Tj 0.233333 0 Td 29.91453 Tz (\) ) Tj 0.251282 0 Td 14.957265 Tz (; ) Tj 0.574359 0 Td 59.081197 Tz (Fhb1 ) Tj 1.364103 0 Td 32.905983 Tz (- ) Tj 0.197436 0 Td 65.811966 Tz (Exon2 ) Tj 62.857143 0 0 62.857143 0 1368.432727 Tm 20.65 0 Td 39.53168 Tz (susceptible ) Tj 2.752273 0 Td 36.826599 Tz (varieties ) Tj 2.147727 0 Td 47.727273 Tz (had ) Tj 1.002273 0 Td 47.064394 Tz (Fhbl ) Tj 1.352273 0 Td 45.738636 Tz (gene ) Tj 1.240909 0 Td 43.939394 Tz (missing ) Tj 2.004545 0 Td 39.507576 Tz (altogether ) Tj 2.593182 0 Td 34.469697 Tz (\( ) Tj 0.175 0 Td 56.565657 Tz (Chi ) Tj 57.142857 0 0 57.142857 0 1322 Tm 5.6 0 Td 44.333333 Tz (part2 ) Tj 55.714286 0 0 55.714286 0 1323 Tm 15.830769 0 Td 50.356125 Tz (primer ) Tj 50.714286 0 0 50.714286 0 1318 Tm 23.169014 0 Td 36.150235 Tz (\( ) Tj 0.157746 0 Td 64.084507 Tz (5' ) Tj 58.571429 0 0 58.571429 0 1329.457956 Tm 22.126829 0 Td 46.95122 Tz (nese ) Tj 1.656098 0 Td 45.528455 Tz (Spring ) Tj 1.621951 0 Td 28.455285 Tz (, ) Tj 0.7 0 Td 68.292683 Tz (NTDHP ) Tj 2.031707 0 Td 25.609756 Tz (, ) Tj 0.682927 0 Td 52.03252 Tz (QiaomaiXiaomai ) Tj 4.421951 0 Td 14.227642 Tz (, ) Tj 0.64878 0 Td 51.995565 Tz (Sanyuehuang ) Tj 3.397561 0 Td 28.455285 Tz (, ) Tj 58.979592 0 0 58.979592 0 1272.789663 Tm 5.476471 0 Td 69.875223 Tz (CCTCACAGGTGTTCTTCTTTGG ) Tj 9.257439 0 Td 25.432526 Tz (- ) Tj 0.186505 0 Td 42.387543 Tz (3 ) Tj 0.322145 0 Td 11.303345 Tz (' ) Tj 0.27128 0 Td 36.735871 Tz (\( ) Tj 0.13564 0 Td 67.820069 Tz (SEQ ) Tj 1.390311 0 Td 52.27797 Tz (ID ) Tj 0.779931 0 Td 74.88466 Tz (NO ) Tj 0.966436 0 Td 11.303345 Tz (: ) Tj 0.152595 0 Td 43.800461 Tz (21 ) Tj 0.627336 0 Td 28.258362 Tz (\) ) Tj 0.220415 0 Td 28.258362 Tz (\) ) Tj 0.23737 0 Td 11.303345 Tz (. ) Tj 0.220415 0 Td 73.471742 Tz (A ) Tj 57.142857 0 0 57.142857 0 1297.496671 Tm 21.77 0 Td 40.833333 Tz (40 ) Tj 0.91 0 Td 55 Tz (Yangmai ) Tj 2.695 0 Td 40.833333 Tz (4 ) Tj 0.385 0 Td 35 Tz (, ) Tj 0.2625 0 Td 51.25 Tz (Yangmai ) Tj 2.6775 0 Td 35 Tz (S ) Tj 0.21 0 Td 35 Tz (, ) Tj 0.3325 0 Td 54.166667 Tz (Yangmai ) Tj 2.6075 0 Td 50.555556 Tz (158 ) Tj 0.945 0 Td 17.5 Tz (, ) Tj 0.49 0 Td 54.583333 Tz (Yangmai ) Tj 2.765 0 Td 23.333333 Tz (1 ) Tj 0.28 0 Td 17.5 Tz (, ) Tj 0.525 0 Td 43.75 Tz (Ernie ) Tj 1.3475 0 Td 29.166667 Tz (, ) Tj 57.653061 0 0 57.653061 0 1255.477361 Tm 22.496637 0 Td 49.144543 Tz (Freedom ) Tj 2.220177 0 Td 34.690265 Tz (, ) Tj 0.503009 0 Td 53.687316 Tz (Wheaton ) Tj 2.220177 0 Td 31.79941 Tz (, ) Tj 0.503009 0 Td 50.383481 Tz (Harding ) Tj 2.012035 0 Td 34.690265 Tz (, ) Tj 0.503009 0 Td 45.097345 Tz (Clark ) Tj 1.387611 0 Td 28.908555 Tz (, ) Tj 0.450973 0 Td 50.589971 Tz (Wesley ) Tj 1.92531 0 Td 28.908555 Tz (\) ) Tj 0.121416 0 Td 28.908555 Tz (, ) Tj 0.450973 0 Td 47.217306 Tz (except ) Tj 1.977345 0 Td 40.471976 Tz (for ) Tj 1.006018 0 Td 40.471976 Tz (5 ) Tj 58.571429 0 0 58.571429 0 1233.308322 Tm 5.497561 0 Td 52.800361 Tz (touchdown ) Tj 3.056098 0 Td 39.430894 Tz (profile ) Tj 1.929268 0 Td 28.455285 Tz (\( ) Tj 0.204878 0 Td 46.95122 Tz (95 ) Tj 0.631707 0 Td 31.300813 Tz ( ) Tj 0.460976 0 Td 44.105691 Tz (C. ) Tj 0.597561 0 Td 25.609756 Tz (- ) Tj 0.221951 0 Td 39.837398 Tz (5 ) Tj 0.495122 0 Td 48.780488 Tz (minutes ) Tj 1.997561 0 Td 25.609756 Tz (, ) Tj 0.443902 0 Td 42.682927 Tz (6 ) Tj 0.512195 0 Td 43.157182 Tz (cycles ) Tj 1.826829 0 Td 46.95122 Tz (of ) Tj 0.768293 0 Td 45.528455 Tz (95 ) Tj 0.631707 0 Td 31.300813 Tz ( ) Tj 0.460976 0 Td 44.105691 Tz (C. ) Tj 0.597561 0 Td 25.609756 Tz (- ) Tj 0.256098 0 Td 28.455285 Tz (1 ) Tj 61.428571 0 0 61.428571 0 1190.528533 Tm 5.24186 0 Td 47.028424 Tz (minute ) Tj 1.660465 0 Td 24.418605 Tz (, ) Tj 0.390698 0 Td 46.124031 Tz (67 ) Tj 0.602326 0 Td 29.844961 Tz ( ) Tj 0.406977 0 Td 42.054264 Tz (C. ) Tj 0.569767 0 Td 24.418605 Tz (- ) Tj 0.244186 0 Td 27.131783 Tz (1 ) Tj 0.406977 0 Td 46.576227 Tz (minute ) Tj 1.855814 0 Td 45.445736 Tz (with ) Tj 1.269767 0 Td 40.697674 Tz (a ) Tj 0.455814 0 Td 43.071705 Tz (decrease ) Tj 2.262791 0 Td 46.124031 Tz (of ) Tj 0.732558 0 Td 27.131783 Tz (1 ) Tj 0.260465 0 Td 29.844961 Tz ( ) Tj 0.406977 0 Td 42.054264 Tz (C. ) Tj 0.716279 0 Td 43.410853 Tz (per ) Tj 0.960465 0 Td 41.782946 Tz (cycle ) Tj 1.302326 0 Td 13.565891 Tz (, ) Tj 55.714286 0 0 55.714286 0 1213.005291 Tm 23.279487 0 Td 46.20133 Tz (landraces ) Tj 2.710256 0 Td 54.444444 Tz (which ) Tj 1.812821 0 Td 54.843305 Tz (had ) Tj 1.184615 0 Td 44.871795 Tz (a ) Tj 0.484615 0 Td 29.91453 Tz (G ) Tj 0.628205 0 Td 20.940171 Tz (> ) Tj 0.448718 0 Td 41.880342 Tz (A ) Tj 0.394872 0 Td 42.478632 Tz (transition ) Tj 2.746154 0 Td 43.376068 Tz (in ) Tj 0.7 0 Td 44.871795 Tz (the ) Tj 1.023077 0 Td 42.628205 Tz (intronic ) Tj 2.261538 0 Td 47.364672 Tz (region ) Tj 55.714286 0 0 55.714286 0 1153.40274 Tm 5.797436 0 Td 52.350427 Tz (72 ) Tj 0.7 0 Td 32.905983 Tz ( ) Tj 0.466667 0 Td 46.367521 Tz (C. ) Tj 0.628205 0 Td 26.923077 Tz (- ) Tj 0.269231 0 Td 29.91453 Tz (1 ) Tj 0.484615 0 Td 51.851852 Tz (minute ) Tj 2.117949 0 Td 52.350427 Tz (30 ) Tj 0.915385 0 Td 49.145299 Tz (seconds ) Tj 2.117949 0 Td 14.957265 Tz (, ) Tj 0.376923 0 Td 49.732906 Tz (followed ) Tj 2.602564 0 Td 55.34188 Tz (by ) Tj 0.915385 0 Td 53.846154 Tz (30 ) Tj 0.897436 0 Td 45.37037 Tz (cycles ) Tj 1.902564 0 Td 50.854701 Tz (of ) Tj 0.807692 0 Td 49.358974 Tz (95 ) Tj 0.664103 0 Td 32.905983 Tz ( ) Tj 55.714286 0 0 55.714286 0 1174.905817 Tm 23.279487 0 Td 47.863248 Tz (4 ) Tj 0.574359 0 Td 52.350427 Tz (bp ) Tj 0.915385 0 Td 51.228632 Tz (upstream ) Tj 2.728205 0 Td 50.854701 Tz (of ) Tj 0.789744 0 Td 45.868946 Tz (the ) Tj 1.112821 0 Td 37.094017 Tz (start ) Tj 1.4 0 Td 49.358974 Tz (of ) Tj 0.807692 0 Td 58.333333 Tz (Exon ) Tj 1.669231 0 Td 47.863248 Tz (2 ) Tj 0.610256 0 Td 35.897436 Tz (\( ) Tj 0.215385 0 Td 56.837607 Tz (Nanda ) Tj 1.992308 0 Td 53.846154 Tz (2419 ) Tj 1.346154 0 Td 14.957265 Tz (, ) Tj 0.412821 0 Td 53.846154 Tz (Funo ) Tj 1.364103 0 Td 26.923077 Tz (, ) Tj 58.571429 0 0 58.571429 0 1135.560626 Tm 22.143902 0 Td 54.065041 Tz (Emai6 ) Tj 1.690244 0 Td 14.227642 Tz (, ) Tj 0.341463 0 Td 47.306911 Tz (Jingzhou ) Tj 2.560976 0 Td 28.455285 Tz (1 ) Tj 0.290244 0 Td 14.227642 Tz (, ) Tj 0.37561 0 Td 57.479675 Tz (Wuhan ) Tj 2.065854 0 Td 34.146341 Tz (3 ) Tj 0.273171 0 Td 34.146341 Tz (\) ) Tj 0.204878 0 Td 34.146341 Tz (. ) Tj 0.32439 0 Td 45.528455 Tz (This ) Tj 1.314634 0 Td 47.306911 Tz (mutation ) Tj 2.47561 0 Td 54.065041 Tz (was ) Tj 1.212195 0 Td 40.469738 Tz (identical ) Tj 52.857143 0 0 52.857143 0 1112 Tm 6.110811 0 Td 48.873874 Tz (C. ) Tj 0.662162 0 Td 28.378378 Tz (- ) Tj 0.283784 0 Td 31.531532 Tz (1 ) Tj 0.491892 0 Td 54.654655 Tz (minute ) Tj 1.92973 0 Td 28.378378 Tz (, ) Tj 0.454054 0 Td 55.18018 Tz (60 ) Tj 0.718919 0 Td 34.684685 Tz ( ) Tj 0.472973 0 Td 48.873874 Tz (C. ) Tj 0.662162 0 Td 28.378378 Tz (- ) Tj 0.283784 0 Td 31.531532 Tz (1 ) Tj 0.491892 0 Td 52.552553 Tz (minute ) Tj 1.92973 0 Td 28.378378 Tz (, ) Tj 0.435135 0 Td 55.18018 Tz (72 ) Tj 0.737838 0 Td 34.684685 Tz ( ) Tj 0.472973 0 Td 48.873874 Tz (C. ) Tj 0.662162 0 Td 28.378378 Tz (- ) Tj 0.283784 0 Td 31.531532 Tz (1 ) Tj 0.491892 0 Td 54.129129 Tz (minute ) Tj 2.194595 0 Td 56.756757 Tz (30 ) Tj 0.927027 0 Td 51.801802 Tz (seconds ) Tj 2.251351 0 Td 15.765766 Tz (, ) Tj 79.438776 0 0 79.438776 0 1078.930825 Tm 4.040848 0 Td 37.764933 Tz (and ) Tj 0.780475 0 Td 33.568829 Tz (a ) Tj 0.314708 0 Td 27.694284 Tz (final ) Tj 0.944123 0 Td 33.335712 Tz (extension ) Tj 1.900835 0 Td 41.961036 Tz (of ) Tj 0.579062 0 Td 31.470777 Tz (72 ) Tj 0.390238 0 Td 35.666881 Tz ( ) Tj 0.188825 0 Td 41.961036 Tz (C. ) Tj 0.541297 0 Td 20.980518 Tz (- ) Tj 0.138471 0 Td 39.862984 Tz (7 ) Tj 0.276943 0 Td 36.865768 Tz (minutes ) Tj 1.560951 0 Td 35.666881 Tz (\) ) Tj 0.239178 0 Td 44.059088 Tz (was ) Tj 0.805652 0 Td 38.289446 Tz (used ) Tj 1.107771 0 Td 27.274674 Tz (for ) Tj 0.528709 0 Td 49.653893 Tz (PCR ) Tj 1.284008 0 Td 30.421751 Tz (45 ) Tj 0.679769 0 Td 32.519803 Tz (to ) Tj 0.428003 0 Td 50.353243 Tz (a ) Tj 0.66718 0 Td 39.563263 Tz (TILLING ) Tj 1.875658 0 Td 39.862984 Tz (mutant ) Tj 1.523186 0 Td 30.072076 Tz (pft528 ) Tj 1.095183 0 Td 44.898309 Tz (which ) Tj 1.397303 0 Td 52.451295 Tz (was ) Tj 0.9693 0 Td 34.617855 Tz (also ) Tj 1.070006 0 Td 36.506101 Tz (found ) Tj 1.296596 0 Td 34.617855 Tz (to ) Tj 0.453179 0 Td 45.108114 Tz (be ) Tj 60 0 0 60 0 1057.748362 Tm 21.633333 0 Td 41.414141 Tz (susceptible ) Tj 2.966667 0 Td 38.888889 Tz (to ) Tj 0.733333 0 Td 64.814815 Tz (FHB ) Tj 1.25 0 Td 11.111111 Tz (. ) Tj 0.35 0 Td 48.888889 Tz (These ) Tj 1.7 0 Td 38.095238 Tz (results ) Tj 1.883333 0 Td 40.625 Tz (indicate ) Tj 2.183333 0 Td 38.888889 Tz (that ) Tj 1.2 0 Td 49.305556 Tz (Fhbl ) Tj 1.516667 0 Td 47.916667 Tz (gene ) Tj 58.571429 0 0 58.571429 0 1032.970075 Tm 5.514634 0 Td 54.065041 Tz (The ) Tj 1.143902 0 Td 45.172764 Tz (products ) Tj 2.356098 0 Td 51.219512 Tz (were ) Tj 1.4 0 Td 48.373984 Tz (run ) Tj 1.041463 0 Td 51.219512 Tz (on ) Tj 0.802439 0 Td 45.528455 Tz (agarose ) Tj 2.1 0 Td 41.260163 Tz (gels ) Tj 1.195122 0 Td 51.219512 Tz (and ) Tj 1.109756 0 Td 48.690154 Tz (sequenced ) Tj 2.782927 0 Td 46.097561 Tz (using ) Tj 61.142857 0 0 61.142857 0 1019.170213 Tm 21.179907 0 Td 43.272975 Tz (provides ) Tj 2.306075 0 Td 40.070093 Tz (resistance ) Tj 2.616822 0 Td 38.161994 Tz (to ) Tj 0.703271 0 Td 63.603323 Tz (FHB ) Tj 1.226636 0 Td 10.903427 Tz (. ) Tj 58.571429 0 0 58.571429 0 996.136564 Tm 5.497561 0 Td 43.631436 Tz (the ) Tj 1.02439 0 Td 48.373984 Tz (Sanger ) Tj 1.980488 0 Td 47.235772 Tz (sequencing ) Tj 3.073171 0 Td 48.373984 Tz (approach ) Tj 2.390244 0 Td 11.382114 Tz (. ) Tj 54.920635 0 0 54.920635 0 983.936275 Tm 23.615896 0 Td 36.416185 Tz (6. ) Tj 0.710116 0 Td 52.727601 Tz (Proposed ) Tj 2.76763 0 Td 65.245665 Tz (Mode ) Tj 1.820809 0 Td 51.589595 Tz (of ) Tj 0.728324 0 Td 51.589595 Tz (Action ) Tj 2.112139 0 Td 50.072254 Tz (of ) Tj 0.76474 0 Td 46.531792 Tz (the ) Tj 1.092486 0 Td 53.865607 Tz (Fhbl ) Tj 1.62052 0 Td 58.41763 Tz (Gene ) Tj 56 0 0 56 0 943.190168 Tm 23.821429 0 Td 56.547619 Tz (The ) Tj 1.196429 0 Td 49.107143 Tz (cloned ) Tj 1.928571 0 Td 52.827381 Tz (Fhbl ) Tj 1.535714 0 Td 51.339286 Tz (gene ) Tj 1.392857 0 Td 47.619048 Tz (has ) Tj 1.053571 0 Td 49.933862 Tz (conserved ) Tj 2.857143 0 Td 53.146259 Tz (domains ) Tj 2.285714 0 Td 14.880952 Tz (, ) Tj 0.285714 0 Td 44.642857 Tz (the ) Tj 1 0 Td 61.309524 Tz (Agglu ) Tj 47.142857 0 0 47.142857 0 916 Tm 12.621212 0 Td 54.545455 Tz (Results ) Tj 2.609091 0 Td 62.457912 Tz (and ) Tj 1.421212 0 Td 57.626263 Tz (Discussion ) Tj 58.571429 0 0 58.571429 0 904.13577 Tm 22.126829 0 Td 39.268293 Tz (tinin ) Tj 1.621951 0 Td 45.528455 Tz (superfamily ) Tj 3.44878 0 Td 52.642276 Tz (domain ) Tj 2.321951 0 Td 50.271003 Tz (and ) Tj 1.331707 0 Td 67.344173 Tz (ETX ) Tj 1.229268 0 Td 28.455285 Tz (/ ) Tj 0.187805 0 Td 71.138211 Tz (MTX2 ) Tj 2.168293 0 Td 45.528455 Tz (superfamily ) Tj 61.428571 0 0 61.428571 0 867.368222 Tm 20.251163 0 Td 36.627907 Tz (50 ) Tj 0.862791 0 Td 50.193798 Tz (domain ) Tj 1.855814 0 Td 10.852713 Tz (. ) Tj 0.17907 0 Td 48.294574 Tz (Agglutinin ) Tj 3.272093 0 Td 43.410853 Tz (superfamily ) Tj 3.223256 0 Td 44.315245 Tz (has ) Tj 1.172093 0 Td 40.358527 Tz (proteins ) Tj 2.327907 0 Td 37.306202 Tz (like ) Tj 1.367442 0 Td 66.925065 Tz (Ama ) Tj 45.714286 0 0 45.714286 0 831 Tm 7.13125 0 Td 40.104167 Tz (1. ) Tj 0.83125 0 Td 70.182292 Tz (Gene ) Tj 2.0125 0 Td 54.6875 Tz (Structure ) Tj 61.428571 0 0 61.428571 0 825.25 Tm 21.113953 0 Td 43.79845 Tz (ranthus ) Tj 2.034884 0 Td 45.445736 Tz (caudatus ) Tj 2.376744 0 Td 39.069767 Tz (agglutinin ) Tj 2.409302 0 Td 27.131783 Tz (, ) Tj 0.374419 0 Td 49.922481 Tz (which ) Tj 1.693023 0 Td 29.844961 Tz (is ) Tj 0.586047 0 Td 40.697674 Tz (a ) Tj 0.439535 0 Td 37.5323 Tz (lectin ) Tj 1.383721 0 Td 10.852713 Tz (. ) Tj 0.244186 0 Td 48.158915 Tz (Although ) Tj 2.506977 0 Td 29.844961 Tz (its ) Tj 58.452381 0 0 58.452381 0 788.841291 Tm 6.158859 0 Td 53.224711 Tz (The ) Tj 1.214664 0 Td 49.185336 Tz (gene ) Tj 1.419959 0 Td 32.790224 Tz (is ) Tj 0.650102 0 Td 46.761711 Tz (3,472 ) Tj 1.642363 0 Td 51.323829 Tz (bp ) Tj 0.889613 0 Td 45.621181 Tz (long ) Tj 1.351527 0 Td 50.373388 Tz (and ) Tj 1.146232 0 Td 41.344196 Tz (consists ) Tj 2.241141 0 Td 48.472505 Tz (of ) Tj 0.752749 0 Td 45.621181 Tz (2 ) Tj 0.547454 0 Td 48.472505 Tz (exons ) Tj 1.522607 0 Td 11.405295 Tz (. ) Tj 0.342159 0 Td 54.175153 Tz (The ) Tj 2.292464 0 Td 42.199593 Tz (biological ) Tj 2.754379 0 Td 44.195519 Tz (function ) Tj 2.309572 0 Td 31.364562 Tz (is ) Tj 0.58167 0 Td 56.211813 Tz (unknown ) Tj 2.343788 0 Td 25.661914 Tz (, ) Tj 0.393483 0 Td 28.513238 Tz (it ) Tj 0.513238 0 Td 46.571623 Tz (has ) Tj 1.043585 0 Td 42.769857 Tz (a ) Tj 0.444807 0 Td 47.759674 Tz (high ) Tj 1.317312 0 Td 46.435845 Tz (binding ) Tj 2.241141 0 Td 49.04277 Tz (speci ) Tj 60.867347 0 0 60.867347 0 752.63244 Tm 5.240905 0 Td 75.984912 Tz (mRNA ) Tj 2.102934 0 Td 31.489243 Tz (is ) Tj 0.624308 0 Td 43.263481 Tz (1,437 ) Tj 1.544342 0 Td 49.28751 Tz (bp ) Tj 0.870746 0 Td 44.495669 Tz (long ) Tj 1.117184 0 Td 10.95278 Tz (. ) Tj 0.345013 0 Td 52.025706 Tz (The ) Tj 1.166471 0 Td 38.60855 Tz (transcript ) Tj 2.546521 0 Td 44.723852 Tz (has ) Tj 1.067896 0 Td 47.918413 Tz (49 ) Tj 0.837888 0 Td 47.918413 Tz (bp ) Tj 0.854317 0 Td 44.495669 Tz (long ) Tj 1.347192 0 Td 38.33473 Tz (5 ) Tj 0.279296 0 Td 10.95278 Tz (' ) Tj 1.429338 0 Td 31.489243 Tz (ficity ) Tj 1.347192 0 Td 39.247462 Tz (for ) Tj 0.7886 0 Td 41.985657 Tz (the ) Tj 0.920034 0 Td 47.918413 Tz (methyl ) Tj 1.757921 0 Td 27.38195 Tz (- ) Tj 0.19715 0 Td 42.289901 Tz (glycoside ) Tj 2.431517 0 Td 47.918413 Tz (of ) Tj 0.640738 0 Td 40.160194 Tz (the ) Tj 0.854317 0 Td 49.28751 Tz (T ) Tj 0.361442 0 Td 32.85834 Tz (- ) Tj 0.164292 0 Td 41.072925 Tz (antigen ) Tj 1.757921 0 Td 32.85834 Tz (, ) Tj 0.3943 0 Td 47.096954 Tz (found ) Tj 1.5772 0 Td 39.703828 Tz (linked ) Tj 58.231293 0 0 58.231293 0 710.861728 Tm 5.529673 0 Td 43.64778 Tz (untranslated ) Tj 3.314369 0 Td 45.794393 Tz (region ) Tj 1.820327 0 Td 50.564642 Tz (and ) Tj 1.099065 0 Td 50.564642 Tz (216 ) Tj 1.116238 0 Td 50.087617 Tz (bp ) Tj 0.824299 0 Td 46.50993 Tz (long ) Tj 1.30514 0 Td 42.932243 Tz (3 ) Tj 0.326285 0 Td 11.448598 Tz (' ) Tj 0.257593 0 Td 43.64778 Tz (untranslated ) Tj 3.314369 0 Td 46.61215 Tz (regions ) Tj 1.854673 0 Td 28.621495 Tz (. ) Tj 1.494042 0 Td 38.639019 Tz (to ) Tj 0.686916 0 Td 41.501168 Tz (serine ) Tj 1.700117 0 Td 44.363318 Tz (or ) Tj 0.686916 0 Td 44.840343 Tz (threonine ) Tj 2.593107 0 Td 43.290012 Tz (residues ) Tj 2.301168 0 Td 47.225467 Tz (of ) Tj 0.704089 0 Td 36.492407 Tz (cell ) Tj 1.099065 0 Td 43.341121 Tz (surface ) Tj 2.009229 0 Td 44.4734 Tz (glycoproteins ) Tj 3.468925 0 Td 28.621495 Tz (. ) Tj 62.857143 0 0 62.857143 0 672.098 Tm 5.138636 0 Td 51.704545 Tz (Exon ) Tj 1.559091 0 Td 26.515152 Tz (1 ) Tj 0.493182 0 Td 43.75 Tz (of ) Tj 0.715909 0 Td 40.656566 Tz (the ) Tj 0.827273 0 Td 53.030303 Tz (gene ) Tj 1.527273 0 Td 42.424242 Tz (has ) Tj 1.05 0 Td 35 Tz (first ) Tj 1.129545 0 Td 42.954545 Tz (Agglutinin ) Tj 2.863636 0 Td 43.38843 Tz (superfamily ) Tj 3.070455 0 Td 42.424242 Tz (con- ) Tj 1.415909 0 Td 34.469697 Tz (55 ) Tj 0.843182 0 Td 50.378788 Tz (The ) Tj 1.288636 0 Td 40.151515 Tz (protein ) Tj 2.084091 0 Td 29.166667 Tz (is ) Tj 0.763636 0 Td 45.664983 Tz (comprised ) Tj 2.863636 0 Td 45.075758 Tz (of ) Tj 0.875 0 Td 39.772727 Tz (a ) Tj 0.684091 0 Td 50.378788 Tz (homodimer ) Tj 2.656818 0 Td 34.469697 Tz (, ) Tj 0.525 0 Td 44.412879 Tz (with ) Tj 1.463636 0 Td 44.412879 Tz (each ) Tj 61.428571 0 0 61.428571 0 632.737399 Tm 5.274419 0 Td 42.958656 Tz (served ) Tj 1.839535 0 Td 50.193798 Tz (domain ) Tj 1.839535 0 Td 13.565891 Tz (, ) Tj 0.146512 0 Td 63.75969 Tz (Exon ) Tj 1.806977 0 Td 43.410853 Tz (2 ) Tj 0.537209 0 Td 44.315245 Tz (has ) Tj 1.074419 0 Td 47.028424 Tz (the ) Tj 1.025581 0 Td 46.124031 Tz (second ) Tj 1.904651 0 Td 44.224806 Tz (Agglutinin ) Tj 2.930233 0 Td 41.149871 Tz (super- ) Tj 2.718605 0 Td 51.851852 Tz (homodimer ) Tj 3.027907 0 Td 41.511628 Tz (consisting ) Tj 2.653488 0 Td 44.767442 Tz (of ) Tj 0.667442 0 Td 52.45478 Tz (two ) Tj 1.106977 0 Td 41.375969 Tz (beta ) Tj 1.04186 0 Td 32.55814 Tz (- ) Tj 0.211628 0 Td 34.496124 Tz (trefoil ) Tj 1.660465 0 Td 48.837209 Tz (domains ) Tj 2.018605 0 Td 32.55814 Tz (. ) Tj 0.390698 0 Td 43.79845 Tz (Epsilon ) Tj 62.857143 0 0 62.857143 0 594.045872 Tm 5.138636 0 Td 42.424242 Tz (family ) Tj 1.925 0 Td 44.486532 Tz (conserved ) Tj 2.784091 0 Td 49.494949 Tz (domain ) Tj 2.163636 0 Td 46.843434 Tz (and ) Tj 1.225 0 Td 57.449495 Tz (ETX ) Tj 1.225 0 Td 18.560606 Tz (- ) Tj 0.015909 0 Td 70.92803 Tz (MTX2 ) Tj 2.131818 0 Td 42.424242 Tz (superfamily ) Tj 4.009091 0 Td 40.30303 Tz (toxin ) Tj 1.495455 0 Td 31.818182 Tz (\( ) Tj 0.206818 0 Td 53.030303 Tz (ETX ) Tj 1.145455 0 Td 23.863636 Tz (\) ) Tj 0.429545 0 Td 45.738636 Tz (produced ) Tj 2.45 0 Td 47.727273 Tz (by ) Tj 0.906818 0 Td 40.013774 Tz (Clostridium ) Tj 2.943182 0 Td 42.424242 Tz (perfringens ) Tj 3.054545 0 Td 42.424242 Tz (type ) Tj 1.272727 0 Td 58.333333 Tz (B ) Tj 61.942857 0 0 61.942857 0 555.756281 Tm 5.230627 0 Td 26.906519 Tz (\( ) Tj 0.193727 0 Td 52.916154 Tz (FIG ) Tj 1.000923 0 Td 10.762608 Tz (. ) Tj 0.339022 0 Td 34.978475 Tz (1 ) Tj 0.355166 0 Td 29.597171 Tz (\) ) Tj 0.048432 0 Td 29.597171 Tz (. ) Tj 0.306734 0 Td 57.400574 Tz (The ) Tj 1.259225 0 Td 40.744157 Tz (protein ) Tj 1.921125 0 Td 30.942497 Tz (is ) Tj 0.645756 0 Td 34.978475 Tz (a ) Tj 0.45203 0 Td 49.440729 Tz (478amino ) Tj 2.615314 0 Td 41.705105 Tz (acid ) Tj 1.210793 0 Td 43.723093 Tz (long ) Tj 1.275369 0 Td 43.050431 Tz (polypeptide ) Tj 4.08441 0 Td 47.53485 Tz (and ) Tj 1.017066 0 Td 67.266298 Tz (D ) Tj 0.565037 0 Td 36.51599 Tz (strains ) Tj 1.727399 0 Td 47.53485 Tz (and ) Tj 1.000923 0 Td 44.29227 Tz (Mosquitocidal ) Tj 3.616236 0 Td 41.436039 Tz (toxin ) Tj 1.420664 0 Td 32.287823 Tz (\( ) Tj 0.096863 0 Td 72.647601 Tz (MTX2 ) Tj 1.711255 0 Td 29.597171 Tz (\) ) Tj 0.258303 0 Td 48.431734 Tz (produced ) Tj 2.470018 0 Td 48.431734 Tz (by ) Tj 62.781955 0 0 62.781955 0 517.793917 Tm 5.14479 0 Td 46.899534 Tz (and ) Tj 1.019401 0 Td 46.014637 Tz (weighs ) Tj 1.879521 0 Td 42.47505 Tz (53.74 ) Tj 1.481317 0 Td 37.165669 Tz (kilo ) Tj 1.099042 0 Td 43.233533 Tz (Daltons ) Tj 2.038802 0 Td 31.856287 Tz (\( ) Tj 0.270778 0 Td 42.652029 Tz (computationally ) Tj 3.997964 0 Td 37.962076 Tz (calculated ) Tj 2.437006 0 Td 21.237525 Tz (, ) Tj 1.258323 0 Td 40.815868 Tz (Bacillus ) Tj 2.134371 0 Td 43.005988 Tz (sphaericus ) Tj 2.771497 0 Td 38.935462 Tz (are ) Tj 0.876048 0 Td 43.802395 Tz (pore ) Tj 1.242395 0 Td 45.129741 Tz (forming ) Tj 2.086587 0 Td 39.820359 Tz (toxins ) Tj 1.497246 0 Td 10.618762 Tz (. ) Tj 0.270778 0 Td 50.439122 Tz (They ) Tj 1.401677 0 Td 39.377911 Tz (attach ) Tj 1.576886 0 Td 35.838323 Tz (to ) Tj 61.428571 0 0 61.428571 0 477.969839 Tm 5.25814 0 Td 53.359173 Tz (FIG ) Tj 1.009302 0 Td 10.852713 Tz (. ) Tj 0.276744 0 Td 43.410853 Tz (2 ) Tj 0.293023 0 Td 27.131783 Tz (\) ) Tj 0.244186 0 Td 10.852713 Tz (. ) Tj 0.260465 0 Td 42.054264 Tz (In ) Tj 0.634884 0 Td 40.697674 Tz (the ) Tj 0.911628 0 Td 49.063307 Tz (accompanying ) Tj 3.711628 0 Td 45.784884 Tz (sequence ) Tj 2.360465 0 Td 31.20155 Tz (file ) Tj 0.944186 0 Td 61.498708 Tz (SEQ ) Tj 1.286047 0 Td 50.193798 Tz (ID ) Tj 0.765116 0 Td 71.899225 Tz (NO ) Tj 0.927907 0 Td 10.852713 Tz (: ) Tj 0.195349 0 Td 27.131783 Tz (1 ) Tj 0.390698 0 Td 31.20155 Tz (is ) Tj 1.627907 0 Td 40.697674 Tz (the ) Tj 1.074419 0 Td 47.48062 Tz (plasma ) Tj 2.034884 0 Td 51.550388 Tz (membranes ) Tj 3.15814 0 Td 46.124031 Tz (of ) Tj 0.813953 0 Td 40.697674 Tz (the ) Tj 1.074419 0 Td 42.054264 Tz (host ) Tj 1.351163 0 Td 47.932817 Tz (and ) Tj 1.188372 0 Td 46.511628 Tz (produce ) Tj 2.27907 0 Td 40.697674 Tz (toxins ) Tj 1.530233 0 Td 13.565891 Tz (, ) Tj 58.630952 0 0 58.630952 0 441.215511 Tm 5.474924 0 Td 42.639594 Tz (the ) Tj 1.159797 0 Td 50.456853 Tz (Fhb1 ) Tj 1.654416 0 Td 49.035533 Tz (gene ) Tj 1.569137 0 Td 47.614213 Tz (sequence ) Tj 2.33665 0 Td 19.898477 Tz (, ) Tj 0.528731 0 Td 63.485618 Tz (SEQ ) Tj 1.535025 0 Td 52.588832 Tz (ID ) Tj 1.006294 0 Td 75.329949 Tz (NO ) Tj 0.972183 0 Td 11.370558 Tz (: ) Tj 0.153503 0 Td 45.482234 Tz (2 ) Tj 0.665178 0 Td 31.269036 Tz (is ) Tj 0.767513 0 Td 42.639594 Tz (the ) Tj 1.125685 0 Td 76.751269 Tz (mRNA ) Tj 3.172386 0 Td 43.857868 Tz (leading ) Tj 2.080812 0 Td 38.375635 Tz (to ) Tj 0.733401 0 Td 41.015228 Tz (altered ) Tj 1.944365 0 Td 44.534687 Tz (permeability ) Tj 3.462335 0 Td 50.219966 Tz (and ) Tj 1.142741 0 Td 37.901861 Tz (ion ) Tj 0.869848 0 Td 25.583756 Tz (- ) Tj 0.187614 0 Td 37.428088 Tz (efflux ) Tj 1.381523 0 Td 25.583756 Tz (, ) Tj 0.426396 0 Td 45.888325 Tz (causing ) Tj 2.166091 0 Td 36.954315 Tz (cell ) Tj 62.116402 0 0 62.116402 0 400.390615 Tm 5.199915 0 Td 47.677238 Tz (complementary ) Tj 3.91201 0 Td 29.51448 Tz (\( ) Tj 0.209284 0 Td 59.699744 Tz (cDNA ) Tj 1.529387 0 Td 29.51448 Tz (\) ) Tj 0.370273 0 Td 44.942504 Tz (sequence ) Tj 2.398722 0 Td 41.588586 Tz (of ) Tj 0.579557 0 Td 52.991908 Tz (Fhb1 ) Tj 1.223509 0 Td 32.197615 Tz (, ) Tj 0.321976 0 Td 59.923339 Tz (SEQ ) Tj 1.255707 0 Td 50.979557 Tz (ID ) Tj 0.756644 0 Td 71.103066 Tz (NO ) Tj 0.917632 0 Td 10.732538 Tz (: ) Tj 0.144889 0 Td 40.247019 Tz (3 ) Tj 0.434668 0 Td 30.856048 Tz (is ) Tj 1.62598 0 Td 39.173765 Tz (death ) Tj 1.207411 0 Td 32.197615 Tz (. ) Tj 0.418569 0 Td 51.873935 Tz (Our ) Tj 1.110818 0 Td 42.393526 Tz (hypothesis ) Tj 2.688501 0 Td 42.930153 Tz (for ) Tj 0.853237 0 Td 45.613288 Tz (the ) Tj 0.998126 0 Td 55.675043 Tz (mode ) Tj 1.545486 0 Td 44.271721 Tz (of ) Tj 0.67615 0 Td 40.694208 Tz (action ) Tj 1.642078 0 Td 45.613288 Tz (of ) Tj 0.67615 0 Td 40.247019 Tz (the ) Tj 0.917632 0 Td 46.284072 Tz (gene ) Tj 1.304003 0 Td 32.197615 Tz (is ) Tj 57.619048 0 0 57.619048 0 365.507614 Tm 5.571074 0 Td 43.38843 Tz (the ) Tj 1.006612 0 Td 44.214876 Tz (protein ) Tj 2.1 0 Td 48.450413 Tz (sequence ) Tj 2.568595 0 Td 49.173554 Tz (of ) Tj 0.780992 0 Td 50.619835 Tz (Fhb1 ) Tj 1.353719 0 Td 11.570248 Tz (. ) Tj 60 0 0 60 0 364.196 Tm 21.6 0 Td 38.888889 Tz (that ) Tj 1.283333 0 Td 41.944444 Tz (agglutinin ) Tj 2.883333 0 Td 44.444444 Tz (superfamily ) Tj 3.283333 0 Td 51.851852 Tz (domain ) Tj 2.216667 0 Td 45.833333 Tz (of ) Tj 0.833333 0 Td 41.666667 Tz (the ) Tj 1.1 0 Td 49.305556 Tz (Fhbl ) Tj 1.6 0 Td 42.063492 Tz (protein ) Tj 59.52381 0 0 59.52381 0 328.479554 Tm 5.4264 0 Td 35 Tz (2. ) Tj 0.672 0 Td 55.3 Tz (Gene ) Tj 1.5456 0 Td 46.2 Tz (Expression ) Tj 58.571429 0 0 58.571429 0 323.720373 Tm 22.143902 0 Td 38.414634 Tz (identifies ) Tj 2.578049 0 Td 42.682927 Tz (the ) Tj 1.058537 0 Td 36.280488 Tz (cell ) Tj 1.195122 0 Td 42.682927 Tz (surface ) Tj 2.082927 0 Td 46.95122 Tz (of ) Tj 0.768293 0 Td 42.682927 Tz (the ) Tj 1.041463 0 Td 44.579946 Tz (fungal ) Tj 1.878049 0 Td 47.306911 Tz (pathogen ) Tj 2.287805 0 Td 28.455285 Tz (, ) Tj 0.478049 0 Td 51.219512 Tz (and ) Tj 1.160976 0 Td 43.631436 Tz (the ) Tj 58.857143 0 0 58.857143 0 286.850667 Tm 6.116505 0 Td 46.723301 Tz (Expression ) Tj 3.177184 0 Td 48.139159 Tz (of ) Tj 0.883495 0 Td 42.475728 Tz (the ) Tj 1.15534 0 Td 49.555016 Tz (gene ) Tj 1.563107 0 Td 52.858684 Tz (was ) Tj 1.393204 0 Td 42.880259 Tz (studied ) Tj 2.174757 0 Td 41.059871 Tz (in ) Tj 0.849515 0 Td 39.014743 Tz (resistant ) Tj 2.497573 0 Td 50.970874 Tz (and ) Tj 2.191748 0 Td 47.43123 Tz (pore ) Tj 1.17233 0 Td 28.317152 Tz (- ) Tj 0.254854 0 Td 46.521036 Tz (forming ) Tj 2.106796 0 Td 43.608414 Tz (toxin ) Tj 1.461165 0 Td 52.386731 Tz (domain ) Tj 2.021845 0 Td 35.679612 Tz (kills ) Tj 1.257282 0 Td 26.901294 Tz (it ) Tj 0.390777 0 Td 11.326861 Tz (. ) Tj 0.254854 0 Td 44.093851 Tz (Protein ) Tj 2.021845 0 Td 41.703442 Tz (subcellular ) Tj 3.007282 0 Td 45.307443 Tz (local ) Tj 70 0 0 70 0 242.645381 Tm 4.628571 0 Td 35.497835 Tz (susceptible ) Tj 2.485714 0 Td 38.690476 Tz (near ) Tj 1.085714 0 Td 36.309524 Tz (isogenic ) Tj 1.985714 0 Td 34.285714 Tz (lines ) Tj 1.1 0 Td 23.809524 Tz (\( ) Tj 0.157143 0 Td 44.642857 Tz (NILs ) Tj 1.114286 0 Td 23.809524 Tz (\) ) Tj 0.2 0 Td 9.52381 Tz (. ) Tj 0.257143 0 Td 45.833333 Tz (Gene ) Tj 1.271429 0 Td 26.190476 Tz (is ) Tj 0.5 0 Td 38.624339 Tz (expressed ) Tj 2.242857 0 Td 34.52381 Tz (in ) Tj 0.757143 0 Td 29.761905 Tz (65 ) Tj 0.728571 0 Td 34.693878 Tz (ization ) Tj 1.628571 0 Td 37.142857 Tz (prediction ) Tj 2.371429 0 Td 40.178571 Tz (software ) Tj 2.214286 0 Td 57.142857 Tz (LOCTREE ) Tj 2.614286 0 Td 35.714286 Tz (3 ) Tj 0.442857 0 Td 45.714286 Tz (shows ) Tj 1.628571 0 Td 33.333333 Tz (that ) Tj 0.9 0 Td 35.714286 Tz (it ) Tj 0.528571 0 Td 40.47619 Tz (is ) Tj 61.142857 0 0 61.142857 0 208.152812 Tm 5.25 0 Td 42.705088 Tz (untreated ) Tj 2.469626 0 Td 37.556248 Tz (resistant ) Tj 2.224299 0 Td 39.979232 Tz (plants ) Tj 1.406542 0 Td 27.258567 Tz (, ) Tj 0.376168 0 Td 43.613707 Tz (but ) Tj 0.981308 0 Td 29.984424 Tz (is ) Tj 0.57243 0 Td 44.781931 Tz (missing ) Tj 2.093458 0 Td 38.161994 Tz (in ) Tj 0.670561 0 Td 40.640045 Tz (susceptible ) Tj 2.86215 0 Td 44.295171 Tz (near ) Tj 2.306075 0 Td 42.932243 Tz (secreted ) Tj 2.126168 0 Td 41.277259 Tz (outside ) Tj 1.897196 0 Td 35.981308 Tz (cells ) Tj 1.242991 0 Td 37.071651 Tz (after ) Tj 1.226636 0 Td 43.341121 Tz (production ) Tj 2.616822 0 Td 27.258567 Tz (, ) Tj 0.310748 0 Td 49.610592 Tz (which ) Tj 1.619159 0 Td 42.250779 Tz (agrees ) Tj 1.684579 0 Td 44.976636 Tz (with ) Tj 1.193925 0 Td 41.796469 Tz (the ) Tj 60.47619 0 0 60.47619 0 173.181818 Tm 5.307874 0 Td 42.716535 Tz (isogenic ) Tj 2.265354 0 Td 38.031496 Tz (lines ) Tj 1.223622 0 Td 13.779528 Tz (. ) Tj 56.285714 0 0 56.285714 0 172.517045 Tm 23.007614 0 Td 51.07868 Tz (proposed ) Tj 2.664975 0 Td 61.44247 Tz (mode ) Tj 1.705584 0 Td 51.818951 Tz (of ) Tj 0.781726 0 Td 44.909757 Tz (action ) Tj 1.652284 0 Td 14.805415 Tz (. ) Tj 32.857143 0 0 32.857143 0 1507 Tm 37.830435 0 Td 65.942029 Tz (35 ) Tj 31.428571 0 0 31.428571 0 1485 Tm 21.127273 0 Td 81.818182 Tz (reverse ) Tj 31.428571 0 0 31.428571 0 1322 Tm 18.677273 0 Td 81.060606 Tz (reverse ) Tj 31.428571 0 0 31.428571 0 468 Tm 39.581818 0 Td 68.939394 Tz (60 ) Tj ET Q endstream endobj 197 0 obj << /Length 1 >> stream q endstream endobj 198 0 obj << /Length 14280 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 65.714286 0 0 65.714286 0 3028 Tm 16.252174 0 Td 78.623188 Tz (US ) Tj 1.33913 0 Td 54.782609 Tz (11,072,799 ) Tj 3.591304 0 Td 68.478261 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.525 0 Td 74.537037 Tz (29 ) Tj 51.428571 0 0 51.428571 0 2973 Tm 33.425 0 Td 77.777778 Tz (30 ) Tj 40.714286 0 0 40.714286 0 2880.40625 Tm 21.221053 0 Td 69.590643 Tz (SEQUENCE ) Tj 3.85614 0 Td 70.175439 Tz (LISTING ) Tj 38.571429 0 0 38.571429 0 2779 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.492593 0 Td 66.255144 Tz (160 ) Tj 1.374074 0 Td 51.851852 Tz (> ) Tj 0.803704 0 Td 74.897119 Tz (NUMBER ) Tj 3.188889 0 Td 71.296296 Tz (OF ) Tj 1.374074 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 66.975309 Tz (ID ) Tj 1.296296 0 Td 72.016461 Tz (NOS ) Tj 1.52963 0 Td 17.283951 Tz (: ) Tj 0.777778 0 Td 64.814815 Tz (27 ) Tj 40 0 0 40 0 2714 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.375 0 Td 50 Tz (1 ) Tj 33.095238 0 0 33.095238 0 2684 Tm 9.789928 0 Td 60.431655 Tz (< ) Tj 0.543885 0 Td 78.896882 Tz (211 ) Tj 1.631655 0 Td 60.431655 Tz (> ) Tj 0.997122 0 Td 85.611511 Tz (LENGTH ) Tj 3.323741 0 Td 20.143885 Tz (: ) Tj 0.906475 0 Td 80.57554 Tz (3472 ) Tj 32.857143 0 0 32.857143 0 2650 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 34.285714 0 0 34.285714 0 2617 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (213 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.933333 0 Td 78.993056 Tz (ORGANISM ) Tj 4.229167 0 Td 24.305556 Tz (: ) Tj 0.875 0 Td 83.854167 Tz (Triticum ) Tj 4.608333 0 Td 83.246528 Tz (aestivum ) Tj 40.571429 0 0 40.571429 0 2545.672986 Tm 7.985915 0 Td 49.295775 Tz (< ) Tj 0.443662 0 Td 64.358372 Tz (400 ) Tj 1.330986 0 Td 49.295775 Tz (> ) Tj 0.81338 0 Td 69.835681 Tz (SEQUENCE ) Tj 3.573944 0 Td 16.431925 Tz (: ) Tj 25.714286 0 0 25.714286 0 2554 Tm 23.45 0 Td 77.777778 Tz (1 ) Tj 42.857143 0 0 42.857143 0 2483.001946 Tm 7.56 0 Td 66.5 Tz (acggccctga ) Tj 4.48 0 Td 66.5 Tz (acactgagca ) Tj 4.456667 0 Td 66.888889 Tz (gtgtgtagta ) Tj 4.503333 0 Td 66.5 Tz (acacaaaata ) Tj 4.48 0 Td 66.888889 Tz (taggaaaaaa ) Tj 4.503333 0 Td 66.5 Tz (atgtttccgc ) Tj 31.428571 0 0 31.428571 0 2486 Tm 49.222727 0 Td 82.19697 Tz (60 ) Tj 42.857143 0 0 42.857143 0 2417 Tm 7.56 0 Td 66.111111 Tz (tgtcagcttt ) Tj 4.456667 0 Td 66.5 Tz (gccgagatgc ) Tj 4.48 0 Td 66.5 Tz (gtcgctctcc ) Tj 4.48 0 Td 66.888889 Tz (gctcaaagca ) Tj 4.503333 0 Td 66.5 Tz (tggcaacagc ) Tj 4.503333 0 Td 66.5 Tz (tacctgcgct ) Tj 30 0 0 30 0 2418 Tm 51.033333 0 Td 87.037037 Tz (120 ) Tj 41.428571 0 0 41.428571 0 2350 Tm 7.82069 0 Td 68.793103 Tz (ccgtgcacga ) Tj 4.634483 0 Td 68.793103 Tz (caagagccag ) Tj 4.610345 0 Td 68.793103 Tz (ggcggcaact ) Tj 4.658621 0 Td 68.390805 Tz (tcgtcgagct ) Tj 4.634483 0 Td 68.793103 Tz (aagcgccgac ) Tj 4.658621 0 Td 69.195402 Tz (aacgacggag ) Tj 30 0 0 30 0 2354 Tm 50.966667 0 Td 90.740741 Tz (180 ) Tj 45.714286 0 0 45.714286 0 2283 Tm 7.065625 0 Td 62.708333 Tz (gcgtcatgaa ) Tj 4.221875 0 Td 61.979167 Tz (cccacgctgc ) Tj 4.2 0 Td 61.979167 Tz (agattctacc ) Tj 4.2 0 Td 61.979167 Tz (tggaggcgtc ) Tj 4.2 0 Td 62.34375 Tz (caaggagcac ) Tj 4.2 0 Td 63.072917 Tz (gacgggctcg ) Tj 30 0 0 30 0 2287 Tm 50.966667 0 Td 88.888889 Tz (240 ) Tj 47.142857 0 0 47.142857 0 2218 Tm 6.872727 0 Td 60.454545 Tz (ttcacgtcag ) Tj 4.072727 0 Td 60.10101 Tz (atgttgctac ) Tj 4.072727 0 Td 60.10101 Tz (aacaacaagt ) Tj 4.072727 0 Td 60.10101 Tz (actgggcgcc ) Tj 4.051515 0 Td 60.808081 Tz (gcagcagcgc ) Tj 4.115152 0 Td 60.808081 Tz (ctgcttcacg ) Tj 32.857143 0 0 32.857143 0 2219 Tm 46.565217 0 Td 81.15942 Tz (300 ) Tj 42.857143 0 0 42.857143 0 2150 Tm 7.536667 0 Td 66.888889 Tz (gcagcgctcg ) Tj 4.503333 0 Td 66.111111 Tz (ctggaccatt ) Tj 4.456667 0 Td 66.888889 Tz (ggtaccgcaa ) Tj 4.503333 0 Td 66.5 Tz (atgagctgga ) Tj 4.456667 0 Td 66.888889 Tz (ggaggatctc ) Tj 4.526667 0 Td 66.5 Tz (tccaagccat ) Tj 28.571429 0 0 28.571429 0 2155 Tm 53.515 0 Td 93.333333 Tz (360 ) Tj 42.857143 0 0 42.857143 0 2084 Tm 7.56 0 Td 66.111111 Tz (catgcaccct ) Tj 4.456667 0 Td 66.5 Tz (gtttaagcac ) Tj 4.503333 0 Td 66.111111 Tz (atccccgtct ) Tj 4.48 0 Td 66.5 Tz (cgggcgagga ) Tj 4.48 0 Td 66.5 Tz (cggctccacc ) Tj 4.503333 0 Td 66.888889 Tz (tgcaggttcg ) Tj 30 0 0 30 0 2086 Tm 51 0 Td 88.888889 Tz (420 ) Tj 45.714286 0 0 45.714286 0 2015.675781 Tm 7.0875 0 Td 62.34375 Tz (tttactgctg ) Tj 4.2 0 Td 61.979167 Tz (taaataattt ) Tj 4.2 0 Td 61.979167 Tz (aagcacgtcc ) Tj 4.2 0 Td 61.979167 Tz (ctctttccac ) Tj 4.2 0 Td 62.34375 Tz (ctctctcgct ) Tj 4.2 0 Td 62.708333 Tz (gctcctgaat ) Tj 28.571429 0 0 28.571429 0 2020 Tm 53.55 0 Td 93.333333 Tz (480 ) Tj 45.714286 0 0 45.714286 0 1948.443171 Tm 7.0875 0 Td 61.979167 Tz (ccagacaggc ) Tj 4.2 0 Td 65.989583 Tz (ctccttaccccccttctctc ) Tj 8.4 0 Td 61.979167 Tz (tcttttcctc ) Tj 4.178125 0 Td 63.072917 Tz (gggtgggccg ) Tj 4.24375 0 Td 62.708333 Tz (agagatgtgg ) Tj 31.428571 0 0 31.428571 0 1954 Tm 48.681818 0 Td 83.080808 Tz (540 ) Tj 50 0 0 50 0 1886 Tm 6.48 0 Td 56.666667 Tz (aagggaggcc ) Tj 3.84 0 Td 57 Tz (cagactaaaa ) Tj 3.82 0 Td 57 Tz (gtaatcgatt ) Tj 3.86 0 Td 57 Tz (tattgggatg ) Tj 3.84 0 Td 57.333333 Tz (catggttega ) Tj 3.86 0 Td 57 Tz (cgttgaggtc ) Tj 32.857143 0 0 32.857143 0 1886 Tm 46.565217 0 Td 81.15942 Tz (600 ) Tj 41.428571 0 0 41.428571 0 1816 Tm 7.796552 0 Td 68.793103 Tz (ggtctggatt ) Tj 4.658621 0 Td 68.390805 Tz (tattgtattt ) Tj 4.610345 0 Td 68.793103 Tz (ggttataaat ) Tj 4.658621 0 Td 68.793103 Tz (aaactaaaaa ) Tj 4.634483 0 Td 68.793103 Tz (ataaacaatt ) Tj 4.634483 0 Td 69.195402 Tz (gggaagaaac ) Tj 30 0 0 30 0 1819 Tm 51.033333 0 Td 87.037037 Tz (660 ) Tj 44.285714 0 0 44.285714 0 1748.673489 Tm 7.316129 0 Td 63.978495 Tz (acgaatgago ) Tj 4.335484 0 Td 64.354839 Tz (aataaactaa ) Tj 4.335484 0 Td 63.978495 Tz (aaataaattt ) Tj 4.335484 0 Td 64.354839 Tz (attgtatttg ) Tj 4.312903 0 Td 64.731183 Tz (gttataaaat ) Tj 4.380645 0 Td 64.731183 Tz (aattcttgaa ) Tj 28.571429 0 0 28.571429 0 1754 Tm 53.55 0 Td 91.388889 Tz (720 ) Tj 41.428571 0 0 41.428571 0 1685 Tm 7.82069 0 Td 68.390805 Tz (togaaagttt ) Tj 4.634483 0 Td 68.390805 Tz (tttccgaggc ) Tj 4.634483 0 Td 68.390805 Tz (atggttgcac ) Tj 4.634483 0 Td 68.793103 Tz (ttgcacgttg ) Tj 4.634483 0 Td 68.793103 Tz (aggtcgccct ) Tj 4.658621 0 Td 68.793103 Tz (ttttctatge ) Tj 30 0 0 30 0 1686 Tm 51.033333 0 Td 87.037037 Tz (780 ) Tj 41.428571 0 0 41.428571 0 1618 Tm 7.82069 0 Td 68.390805 Tz (atgcttgcat ) Tj 4.610345 0 Td 69.195402 Tz (gttgatgtga ) Tj 4.658621 0 Td 68.793103 Tz (catgtttgca ) Tj 4.634483 0 Td 68.793103 Tz (tgttgaaaaa ) Tj 4.634483 0 Td 69.195402 Tz (tttcttaatg ) Tj 4.634483 0 Td 69.597701 Tz (ggatcagtta ) Tj 30 0 0 30 0 1619 Tm 51.033333 0 Td 87.037037 Tz (840 ) Tj 42.857143 0 0 42.857143 0 1551 Tm 7.56 0 Td 66.111111 Tz (tttagttogt ) Tj 4.48 0 Td 66.5 Tz (ataggattaa ) Tj 4.48 0 Td 66.111111 Tz (tagggatcat ) Tj 4.456667 0 Td 66.888889 Tz (gcagatttta ) Tj 4.503333 0 Td 66.5 Tz (tgtatccact ) Tj 4.48 0 Td 66.888889 Tz (gtgatgtact ) Tj 31.428571 0 0 31.428571 0 1552 Tm 48.65 0 Td 86.616162 Tz (900 ) Tj 45.714286 0 0 45.714286 0 1482.840156 Tm 7.0875 0 Td 62.34375 Tz (agtgttagag ) Tj 4.2 0 Td 61.979167 Tz (caactctatc ) Tj 4.2 0 Td 62.34375 Tz (aacatcgtca ) Tj 4.2 0 Td 62.34375 Tz (atctaccctg ) Tj 4.2 0 Td 62.34375 Tz (tcgccattat ) Tj 4.221875 0 Td 62.708333 Tz (aaccgtttga ) Tj 28.571429 0 0 28.571429 0 1488 Tm 53.55 0 Td 91.388889 Tz (960 ) Tj 44.285714 0 0 44.285714 0 1417.833333 Tm 7.316129 0 Td 64.354839 Tz (caaaatgata ) Tj 4.312903 0 Td 64.731183 Tz (gtctagcaga ) Tj 4.335484 0 Td 64.354839 Tz (gtcgccatct ) Tj 4.358065 0 Td 63.978495 Tz (tgtcggggat ) Tj 4.335484 0 Td 64.354839 Tz (catcataatt ) Tj 4.358065 0 Td 64.354839 Tz (tatgaagcac ) Tj 30 0 0 30 0 1419 Tm 50.433333 0 Td 90.277778 Tz (1020 ) Tj 48.571429 0 0 48.571429 0 1348.840156 Tm 6.670588 0 Td 58.333333 Tz (cctccatatc ) Tj 3.952941 0 Td 58.676471 Tz (tggcctctca ) Tj 3.932353 0 Td 58.676471 Tz (ggcgccatat ) Tj 3.973529 0 Td 58.333333 Tz (atagcgcctc ) Tj 3.932353 0 Td 59.019608 Tz (ggggttgcgt ) Tj 3.994118 0 Td 59.019608 Tz (tttagataca ) Tj 32.857143 0 0 32.857143 0 1352 Tm 46.047826 0 Td 82.427536 Tz (1080 ) Tj 41.428571 0 0 41.428571 0 1285 Tm 7.82069 0 Td 68.390805 Tz (tagcccacgt ) Tj 4.610345 0 Td 68.793103 Tz (ggttgatact ) Tj 4.658621 0 Td 68.793103 Tz (tactctagta ) Tj 4.634483 0 Td 68.793103 Tz (tacaaaggag ) Tj 4.634483 0 Td 68.793103 Tz (atgatatgat ) Tj 4.634483 0 Td 69.597701 Tz (gtccatttag ) Tj 32.857143 0 0 32.857143 0 1285 Tm 46.047826 0 Td 82.427536 Tz (1140 ) Tj 45.714286 0 0 45.714286 0 1216.659824 Tm 7.0875 0 Td 61.979167 Tz (tatgtaagct ) Tj 4.2 0 Td 61.979167 Tz (tgacattcac ) Tj 4.2 0 Td 61.979167 Tz (aagattatct ) Tj 4.2 0 Td 62.34375 Tz (aaaaattata ) Tj 4.2 0 Td 62.34375 Tz (aaactattct ) Tj 4.221875 0 Td 62.34375 Tz (tttgatcttt ) Tj 28.571429 0 0 28.571429 0 1222 Tm 52.92 0 Td 94.791667 Tz (1200 ) Tj 42.857143 0 0 42.857143 0 1150.003902 Tm 7.56 0 Td 66.5 Tz (tgaactgtta ) Tj 4.48 0 Td 66.5 Tz (atctaatgta ) Tj 4.48 0 Td 66.111111 Tz (cactcatttt ) Tj 4.48 0 Td 66.111111 Tz (cacagtttac ) Tj 4.48 0 Td 66.5 Tz (ttaattactt ) Tj 4.503333 0 Td 66.888889 Tz (accttgtaca ) Tj 28.571429 0 0 28.571429 0 1155 Tm 52.92 0 Td 94.791667 Tz (1260 ) Tj 45.714286 0 0 45.714286 0 1086 Tm 7.0875 0 Td 62.34375 Tz (agtactgcaa ) Tj 4.2 0 Td 61.979167 Tz (acgaaatgtt ) Tj 4.178125 0 Td 62.34375 Tz (gtgttcttat ) Tj 4.221875 0 Td 61.979167 Tz (tggtcatgac ) Tj 4.2 0 Td 62.708333 Tz (tccaagaaga ) Tj 4.221875 0 Td 62.708333 Tz (cgtcttctag ) Tj 31.428571 0 0 31.428571 0 1088 Tm 48.140909 0 Td 86.174242 Tz (1320 ) Tj 44.285714 0 0 44.285714 0 1016.835603 Tm 7.293548 0 Td 64.731183 Tz (gctcattgga ) Tj 4.358065 0 Td 64.354839 Tz (attcttctaa ) Tj 4.335484 0 Td 64.354839 Tz (ctagatgtta ) Tj 4.335484 0 Td 63.978495 Tz (ccctgtgtgt ) Tj 4.335484 0 Td 64.731183 Tz (tgctgcgaca ) Tj 4.358065 0 Td 64.731183 Tz (aatgtttgca ) Tj 32.857143 0 0 32.857143 0 1020 Tm 46.047826 0 Td 82.427536 Tz (1380 ) Tj 44.285714 0 0 44.285714 0 952 Tm 7.293548 0 Td 64.731183 Tz (gcatatttca ) Tj 4.335484 0 Td 64.731183 Tz (gtgggatttg ) Tj 4.358065 0 Td 64.354839 Tz (attatatgaa ) Tj 4.335484 0 Td 63.978495 Tz (catgatattt ) Tj 4.312903 0 Td 65.107527 Tz (gcatgaataa ) Tj 4.380645 0 Td 64.731183 Tz (taaggactaa ) Tj 30 0 0 30 0 954 Tm 50.433333 0 Td 90.277778 Tz (1440 ) Tj 45.714286 0 0 45.714286 0 883.837891 Tm 7.0875 0 Td 62.34375 Tz (aagcccaata ) Tj 4.2 0 Td 61.979167 Tz (atccatttct ) Tj 4.2 0 Td 61.979167 Tz (aaacccaggc ) Tj 4.2 0 Td 61.979167 Tz (tcatctgcac ) Tj 4.2 0 Td 62.34375 Tz (ccgcgttgac ) Tj 4.2 0 Td 62.708333 Tz (gaaaaaaatc ) Tj 31.428571 0 0 31.428571 0 888 Tm 48.109091 0 Td 86.174242 Tz (1500 ) Tj 42.857143 0 0 42.857143 0 816.007805 Tm 7.56 0 Td 66.5 Tz (aaaacaaata ) Tj 4.48 0 Td 66.111111 Tz (ctataaaaat ) Tj 4.48 0 Td 66.5 Tz (taaaaaaaaa ) Tj 4.48 0 Td 66.111111 Tz (atcaactttt ) Tj 4.48 0 Td 66.5 Tz (tttgtgtggt ) Tj 4.503333 0 Td 66.888889 Tz (agataatttg ) Tj 30 0 0 30 0 822 Tm 50.4 0 Td 90.277778 Tz (1560 ) Tj 42.857143 0 0 42.857143 0 751.006816 Tm 7.536667 0 Td 66.888889 Tz (gagccgtgag ) Tj 4.48 0 Td 66.5 Tz (gttcgctcct ) Tj 4.503333 0 Td 66.111111 Tz (attttcaaat ) Tj 4.48 0 Td 66.5 Tz (catttggaca ) Tj 4.48 0 Td 66.5 Tz (tttgtgccgc ) Tj 4.503333 0 Td 66.888889 Tz (tctcggaaaa ) Tj 31.428571 0 0 31.428571 0 754 Tm 48.140909 0 Td 86.174242 Tz (1620 ) Tj 42.857143 0 0 42.857143 0 687 Tm 7.56 0 Td 66.111111 Tz (aaagacaaat ) Tj 4.48 0 Td 66.5 Tz (ccgggttctg ) Tj 4.48 0 Td 66.111111 Tz (taaaaaaagt ) Tj 4.48 0 Td 66.5 Tz (ttactgttca ) Tj 4.48 0 Td 66.5 Tz (cgcacttttt ) Tj 4.48 0 Td 66.888889 Tz (gacccgattt ) Tj 34.285714 0 0 34.285714 0 687 Tm 44.129167 0 Td 78.993056 Tz (1680 ) Tj 44.285714 0 0 44.285714 0 619 Tm 7.293548 0 Td 64.731183 Tz (gtcttttttg ) Tj 4.358065 0 Td 64.354839 Tz (ctgagagtta ) Tj 4.335484 0 Td 63.978495 Tz (ctcagatgtc ) Tj 4.335484 0 Td 63.978495 Tz (taaatgattt ) Tj 4.312903 0 Td 65.107527 Tz (gaaaattaga ) Tj 4.358065 0 Td 65.107527 Tz (gcgaaccaca ) Tj 30 0 0 30 0 621 Tm 50.433333 0 Td 90.277778 Tz (1740 ) Tj 44.285714 0 0 44.285714 0 552.671233 Tm 7.316129 0 Td 63.978495 Tz (agcatcaaat ) Tj 4.335484 0 Td 63.978495 Tz (tatctaccac ) Tj 4.335484 0 Td 63.978495 Tz (acaaaataat ) Tj 4.335484 0 Td 63.978495 Tz (tttgattttt ) Tj 4.335484 0 Td 64.354839 Tz (ttctagtatt ) Tj 4.358065 0 Td 64.354839 Tz (tgttttgaat ) Tj 30 0 0 30 0 555 Tm 50.433333 0 Td 90.277778 Tz (1800 ) Tj 40 0 0 40 0 486.015267 Tm 8.1 0 Td 75.625 Tz (tttttcctaaccgagtgagg ) Tj 9.6 0 Td 70.833333 Tz (atgagcctgt ) Tj 4.775 0 Td 71.666667 Tz (gcaccggaaa ) Tj 4.825 0 Td 71.25 Tz (cgccgcaccc ) Tj 4.825 0 Td 71.666667 Tz (ctaaaaccca ) Tj 30 0 0 30 0 490 Tm 50.433333 0 Td 90.277778 Tz (1860 ) Tj 42.857143 0 0 42.857143 0 418.005837 Tm 7.56 0 Td 66.111111 Tz (aaatacatat ) Tj 4.456667 0 Td 66.888889 Tz (gottaatgca ) Tj 4.503333 0 Td 66.5 Tz (taattataaa ) Tj 4.48 0 Td 66.5 Tz (atatatattg ) Tj 4.48 0 Td 66.888889 Tz (attatcacta ) Tj 4.503333 0 Td 66.888889 Tz (tggtaatata ) Tj 31.428571 0 0 31.428571 0 422 Tm 48.109091 0 Td 86.174242 Tz (1920 ) Tj 42.857143 0 0 42.857143 0 352.996086 Tm 7.56 0 Td 66.111111 Tz (tttataaagt ) Tj 4.48 0 Td 66.111111 Tz (tcgaaccttt ) Tj 4.48 0 Td 66.111111 Tz (ttgtgtgcat ) Tj 4.48 0 Td 66.111111 Tz (agttatatct ) Tj 4.48 0 Td 66.5 Tz (tgatgtttgt ) Tj 4.503333 0 Td 66.5 Tz (cttttcccat ) Tj 30 0 0 30 0 356 Tm 50.4 0 Td 90.277778 Tz (1980 ) Tj 45.714286 0 0 45.714286 0 288 Tm 7.065625 0 Td 62.34375 Tz (gcatggttgt ) Tj 4.221875 0 Td 61.979167 Tz (atgttgaggc ) Tj 4.178125 0 Td 62.708333 Tz (ggcattattg ) Tj 4.221875 0 Td 61.979167 Tz (atgttgaggt ) Tj 4.2 0 Td 62.708333 Tz (aaatatgtta ) Tj 4.2 0 Td 62.708333 Tz (gtgggatcac ) Tj 30 0 0 30 0 289 Tm 50.4 0 Td 91.666667 Tz (2040 ) Tj 41.428571 0 0 41.428571 0 217 Tm 7.82069 0 Td 68.390805 Tz (ctacttagct ) Tj 4.634483 0 Td 68.793103 Tz (atatatggca ) Tj 4.634483 0 Td 68.390805 Tz (cacgctacat ) Tj 4.634483 0 Td 68.793103 Tz (tgcttaaata ) Tj 4.634483 0 Td 69.195402 Tz (aatagtctca ) Tj 4.658621 0 Td 69.195402 Tz (tattttggtg ) Tj 31.428571 0 0 31.428571 0 219 Tm 48.077273 0 Td 87.5 Tz (2100 ) Tj ET Q endstream endobj 199 0 obj << /Length 1 >> stream q endstream endobj 200 0 obj << /Length 14130 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.486111 0 Td 71.296296 Tz (31 ) Tj 54.285714 0 0 54.285714 0 2971 Tm 31.665789 0 Td 73.684211 Tz (32 ) Tj 47.142857 0 0 47.142857 0 2908 Tm 23.990909 0 Td 42.424242 Tz (- ) Tj 0.424242 0 Td 78.563412 Tz (continued ) Tj 44.285714 0 0 44.285714 0 2806.832195 Tm 7.316129 0 Td 63.978495 Tz (tatgtcaacc ) Tj 4.335484 0 Td 64.354839 Tz (agcagggata ) Tj 4.335484 0 Td 63.978495 Tz (cagcctgact ) Tj 4.335484 0 Td 64.354839 Tz (ttcgtgatta ) Tj 4.335484 0 Td 64.354839 Tz (tctctcccat ) Tj 4.358065 0 Td 64.731183 Tz (cttatgtttg ) Tj 30 0 0 30 0 2809 Tm 50.4 0 Td 91.666667 Tz (2160 ) Tj 41.428571 0 0 41.428571 0 2741 Tm 7.82069 0 Td 68.793103 Tz (caatcgtttg ) Tj 4.634483 0 Td 68.793103 Tz (tttgtacatg ) Tj 4.610345 0 Td 68.793103 Tz (gcaggttcct ) Tj 4.658621 0 Td 68.793103 Tz (tcattcccag ) Tj 4.634483 0 Td 68.793103 Tz (ctaggaaaat ) Tj 4.658621 0 Td 68.793103 Tz (atgcttgcgt ) Tj 31.428571 0 0 31.428571 0 2743 Tm 48.077273 0 Td 87.5 Tz (2220 ) Tj 42.857143 0 0 42.857143 0 2674 Tm 7.536667 0 Td 66.5 Tz (gctatccagt ) Tj 4.503333 0 Td 66.111111 Tz (tctgatatgt ) Tj 4.48 0 Td 66.111111 Tz (ccaagcaccc ) Tj 4.48 0 Td 66.111111 Tz (ctacttgcat ) Tj 4.48 0 Td 66.888889 Tz (atagcacgtg ) Tj 4.503333 0 Td 66.888889 Tz (aagaatctga ) Tj 34.285714 0 0 34.285714 0 2676 Tm 44.070833 0 Td 80.208333 Tz (2280 ) Tj 45.714286 0 0 45.714286 0 2607 Tm 7.0875 0 Td 61.979167 Tz (tcaagataat ) Tj 4.2 0 Td 62.34375 Tz (ctccttgatg ) Tj 4.2 0 Td 61.979167 Tz (cttttactgt ) Tj 4.2 0 Td 62.34375 Tz (ccttgatgtg ) Tj 4.2 0 Td 62.708333 Tz (t?agaacaga ) Tj 4.221875 0 Td 62.34375 Tz (tgcagttgcc ) Tj 30 0 0 30 0 2609 Tm 50.4 0 Td 91.666667 Tz (2340 ) Tj 47.142857 0 0 47.142857 0 2541 Tm 6.872727 0 Td 60.10101 Tz (tagttatctt ) Tj 4.051515 0 Td 60.808081 Tz (gctttcaaag ) Tj 4.072727 0 Td 60.808081 Tz (gcgacaatgg ) Tj 4.072727 0 Td 60.454545 Tz (gaggttcctt ) Tj 4.072727 0 Td 61.161616 Tz (ggtgcgaaga ) Tj 4.115152 0 Td 60.808081 Tz (tcgtcgaggg ) Tj 30 0 0 30 0 2544 Tm 50.4 0 Td 91.666667 Tz (2400 ) Tj 41.428571 0 0 41.428571 0 2474 Tm 7.82069 0 Td 68.390805 Tz (ttatagatat ) Tj 4.634483 0 Td 68.390805 Tz (cttgaatact ) Tj 4.634483 0 Td 68.793103 Tz (ccaaagatga ) Tj 4.634483 0 Td 68.390805 Tz (tattggagat ) Tj 4.634483 0 Td 68.793103 Tz (ctaagtgtgt ) Tj 4.658621 0 Td 68.793103 Tz (tgcacacaat ) Tj 32.857143 0 0 32.857143 0 2476 Tm 45.986957 0 Td 83.695652 Tz (2460 ) Tj 45.714286 0 0 45.714286 0 2405.678049 Tm 7.0875 0 Td 61.979167 Tz (tttcaccaat ) Tj 4.2 0 Td 62.34375 Tz (aaagatggag ) Tj 4.2 0 Td 61.979167 Tz (ttgtccgtat ) Tj 4.2 0 Td 61.979167 Tz (aaaatccaac ) Tj 4.2 0 Td 62.708333 Tz (tatttcgaca ) Tj 4.221875 0 Td 62.708333 Tz (tgttttggag ) Tj 31.428571 0 0 31.428571 0 2410 Tm 48.109091 0 Td 87.5 Tz (2520 ) Tj 42.857143 0 0 42.857143 0 2340.994152 Tm 7.536667 0 Td 66.888889 Tz (gcgaagccca ) Tj 4.503333 0 Td 66.111111 Tz (aattggatct ) Tj 4.456667 0 Td 66.5 Tz (gggctgatto ) Tj 4.503333 0 Td 66.111111 Tz (aactgacacc ) Tj 4.48 0 Td 66.888889 Tz (acccacaaca ) Tj 4.503333 0 Td 66.5 Tz (accgtgatac ) Tj 28.571429 0 0 28.571429 0 2345 Tm 52.885 0 Td 96.25 Tz (2580 ) Tj 44.285714 0 0 44.285714 0 2275 Tm 7.316129 0 Td 64.354839 Tz (attattcaag ) Tj 4.312903 0 Td 64.731183 Tz (gtgaccactg ) Tj 4.335484 0 Td 64.354839 Tz (ggcccgactt ) Tj 4.358065 0 Td 64.354839 Tz (cattgctctg ) Tj 4.335484 0 Td 64.731183 Tz (cgaaacttgg ) Tj 4.335484 0 Td 65.107527 Tz (gcaacaacaa ) Tj 28.571429 0 0 28.571429 0 2279 Tm 52.885 0 Td 96.25 Tz (2640 ) Tj 42.857143 0 0 42.857143 0 2208 Tm 7.56 0 Td 66.5 Tz (tttctgcaaa ) Tj 4.48 0 Td 66.5 Tz (aggttaacca ) Tj 4.48 0 Td 66.111111 Tz (cagaagggaa ) Tj 4.573333 0 Td 66.111111 Tz (gtatgattgc ) Tj 4.386667 0 Td 70.777778 Tz (ctcaatgctgctgttggttc ) Tj 32.857143 0 0 32.857143 0 2210 Tm 45.986957 0 Td 83.695652 Tz (2700 ) Tj 42.857143 0 0 42.857143 0 2142 Tm 7.56 0 Td 66.111111 Tz (catcacagct ) Tj 4.456667 0 Td 66.888889 Tz (gaagtaaaaa ) Tj 4.503333 0 Td 66.111111 Tz (tgcggtgcat ) Tj 4.48 0 Td 66.111111 Tz (tgaaccaatt ) Tj 4.456667 0 Td 67.277778 Tz (gtttctcgag ) Tj 4.526667 0 Td 66.888889 Tz (acatctatga ) Tj 32.857143 0 0 32.857143 0 2145 Tm 45.986957 0 Td 83.695652 Tz (2760 ) Tj 42.857143 0 0 42.857143 0 2074.006816 Tm 7.56 0 Td 66.111111 Tz (tgttgatttt ) Tj 4.48 0 Td 66.5 Tz (cgcctaggtg ) Tj 4.48 0 Td 66.111111 Tz (aagctaagat ) Tj 4.48 0 Td 66.111111 Tz (ctacaccaat ) Tj 4.456667 0 Td 67.277778 Tz (ggtattgagg ) Tj 4.503333 0 Td 67.277778 Tz (gccttgatag ) Tj 30 0 0 30 0 2077 Tm 50.4 0 Td 91.666667 Tz (2820 ) Tj 47.142857 0 0 47.142857 0 2007.675781 Tm 6.872727 0 Td 60.10101 Tz (tcaaattgtt ) Tj 4.051515 0 Td 60.808081 Tz (gaaaacatga ) Tj 4.093939 0 Td 60.10101 Tz (ccaccacaac ) Tj 41.428571 0 0 41.428571 0 2006.003906 Tm 21.724138 0 Td 68.390805 Tz (aaacaaaacc ) Tj 4.634483 0 Td 68.793103 Tz (aaaatgatct ) Tj 4.658621 0 Td 68.793103 Tz (tcacatacac ) Tj 31.428571 0 0 31.428571 0 2011 Tm 48.077273 0 Td 87.5 Tz (2880 ) Tj 44.285714 0 0 44.285714 0 1943 Tm 7.316129 0 Td 63.978495 Tz (aaataccgtc ) Tj 4.335484 0 Td 63.978495 Tz (cagagtacct ) Tj 4.312903 0 Td 64.354839 Tz (ggagttctac ) Tj 4.358065 0 Td 64.354839 Tz (tgtttcattg ) Tj 4.335484 0 Td 64.731183 Tz (aagattggcg ) Tj 4.358065 0 Td 64.731183 Tz (tcaagaccaa ) Tj 30 0 0 30 0 1944 Tm 50.4 0 Td 91.666667 Tz (2940 ) Tj 47.142857 0 0 47.142857 0 1874.841285 Tm 6.872727 0 Td 60.10101 Tz (atttaaatcc ) Tj 4.051515 0 Td 60.454545 Tz (gggattccat ) Tj 4.093939 0 Td 60.454545 Tz (ttgtagttga ) Tj 4.072727 0 Td 60.10101 Tz (cggcgaagtt ) Tj 4.051515 0 Td 61.161616 Tz (gaggtcagca ) Tj 4.115152 0 Td 60.808081 Tz (ctgagtttag ) Tj 31.428571 0 0 31.428571 0 1878 Tm 48.109091 0 Td 87.5 Tz (3000 ) Tj 42.857143 0 0 42.857143 0 1809 Tm 7.56 0 Td 66.111111 Tz (togatcatat ) Tj 4.48 0 Td 66.5 Tz (acctgggggg ) Tj 4.456667 0 Td 66.5 Tz (gagccaaatc ) Tj 4.503333 0 Td 66.5 Tz (tgacacaaaa ) Tj 4.456667 0 Td 67.277778 Tz (gtagtaagca ) Tj 4.526667 0 Td 66.888889 Tz (aacaaattga ) Tj 32.857143 0 0 32.857143 0 1812 Tm 45.986957 0 Td 83.695652 Tz (3060 ) Tj 44.285714 0 0 44.285714 0 1743 Tm 7.316129 0 Td 63.978495 Tz (tgttgaagtt ) Tj 4.335484 0 Td 64.354839 Tz (cctccaatga ) Tj 4.335484 0 Td 63.978495 Tz (agaaagtgac ) Tj 4.335484 0 Td 64.354839 Tz (agtaaaagcg ) Tj 4.335484 0 Td 64.731183 Tz (attggatcaa ) Tj 4.358065 0 Td 64.731183 Tz (acggtttatg ) Tj 30 0 0 30 0 1745 Tm 50.4 0 Td 91.666667 Tz (3120 ) Tj 42.857143 0 0 42.857143 0 1674.005848 Tm 7.56 0 Td 66.111111 Tz (tgatatacct ) Tj 4.48 0 Td 66.5 Tz (ttctcataca ) Tj 4.48 0 Td 66.5 Tz (agcagaggga ) Tj 4.48 0 Td 66.111111 Tz (tattctaacc ) Tj 4.48 0 Td 66.888889 Tz (aatggagatg ) Tj 4.503333 0 Td 66.888889 Tz (aagttatcca ) Tj 30 0 0 30 0 1678 Tm 50.4 0 Td 91.666667 Tz (3180 ) Tj 42.857143 0 0 42.857143 0 1606.996094 Tm 7.56 0 Td 66.111111 Tz (agaattcacc ) Tj 4.456667 0 Td 66.5 Tz (gatggcatgt ) Tj 4.503333 0 Td 66.111111 Tz (attttggtgt ) Tj 4.48 0 Td 66.111111 Tz (taaaacctcc ) Tj 4.48 0 Td 66.5 Tz (agcatcacgt ) Tj 4.503333 0 Td 66.888889 Tz (tccataccaa ) Tj 31.428571 0 0 31.428571 0 1611 Tm 48.077273 0 Td 87.5 Tz (3240 ) Tj 41.428571 0 0 41.428571 0 1543 Tm 7.82069 0 Td 68.390805 Tz (agaagaacac ) Tj 4.634483 0 Td 68.793103 Tz (ctgtgaggag ) Tj 4.610345 0 Td 69.195402 Tz (gactgaagag ) Tj 4.634483 0 Td 69.195402 Tz (gtgtgcatgg ) Tj 4.634483 0 Td 69.597701 Tz (gtcgtgagag ) Tj 4.658621 0 Td 69.597701 Tz (gtgaaaccta ) Tj 34.285714 0 0 34.285714 0 1543 Tm 44.1 0 Td 80.208333 Tz (3300 ) Tj 41.428571 0 0 41.428571 0 1477 Tm 7.82069 0 Td 68.390805 Tz (catcagatgt ) Tj 4.610345 0 Td 69.195402 Tz (gctacctaaa ) Tj 4.658621 0 Td 68.793103 Tz (taaagatgta ) Tj 4.610345 0 Td 68.793103 Tz (gtgaacatgc ) Tj 4.634483 0 Td 69.195402 Tz (gtatatgaat ) Tj 4.658621 0 Td 69.195402 Tz (gggtcgtggc ) Tj 28.571429 0 0 28.571429 0 1480 Tm 52.885 0 Td 96.25 Tz (3360 ) Tj 45.714286 0 0 45.714286 0 1409.839024 Tm 7.0875 0 Td 62.34375 Tz (ttgttttcga ) Tj 4.2 0 Td 61.979167 Tz (tggagctggt ) Tj 4.2 0 Td 61.979167 Tz (ttgagtgctt ) Tj 4.2 0 Td 61.979167 Tz (tctttccttc ) Tj 4.2 0 Td 62.708333 Tz (ctatgtgttg ) Tj 4.2 0 Td 62.708333 Tz (ggaataaaat ) Tj 30 0 0 30 0 1412 Tm 50.4 0 Td 91.666667 Tz (3420 ) Tj 43.809524 0 0 43.809524 0 1343.16198 Tm 7.372826 0 Td 65.054348 Tz (ctaagtttag ) Tj 4.359783 0 Td 65.434783 Tz (gatgtatttg ) Tj 4.382609 0 Td 65.434783 Tz (gtttgacgaa ) Tj 4.405435 0 Td 65.054348 Tz (atcaatatta ) Tj 4.382609 0 Td 65.054348 Tz (taattattat ) Tj 4.405435 0 Td 60.869565 Tz (ca ) Tj 31.428571 0 0 31.428571 0 1345 Tm 48.109091 0 Td 86.174242 Tz (3472 ) Tj 38.571429 0 0 38.571429 0 1241 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.4 0 Td 51.851852 Tz (2 ) Tj 31.428571 0 0 31.428571 0 1212 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.986364 0 Td 84.848485 Tz (1437 ) Tj 31.428571 0 0 31.428571 0 1178 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 34.285714 0 0 34.285714 0 1144 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (213 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.933333 0 Td 79.600694 Tz (ORGANISM ) Tj 4.229167 0 Td 24.305556 Tz (: ) Tj 0.875 0 Td 83.854167 Tz (Triticum ) Tj 4.608333 0 Td 83.246528 Tz (aestivum ) Tj 38.809524 0 0 38.809524 0 1074.318386 Tm 8.348466 0 Td 51.533742 Tz (< ) Tj 0.463804 0 Td 67.280164 Tz (400 ) Tj 1.391411 0 Td 51.533742 Tz (> ) Tj 0.850307 0 Td 73.006135 Tz (SEQUENCE ) Tj 3.736196 0 Td 17.177914 Tz (: ) Tj 0.747239 0 Td 51.533742 Tz (2 ) Tj 42.857143 0 0 42.857143 0 1011 Tm 7.56 0 Td 66.111111 Tz (atgtttccgc ) Tj 4.48 0 Td 66.111111 Tz (tgtcagcttt ) Tj 4.456667 0 Td 66.5 Tz (gccgagatgc ) Tj 4.48 0 Td 66.5 Tz (gtcgctctcc ) Tj 4.48 0 Td 67.277778 Tz (gctcaaagca ) Tj 4.526667 0 Td 66.5 Tz (tggcaacagc ) Tj 28.571429 0 0 28.571429 0 1014 Tm 54.145 0 Td 87.5 Tz (60 ) Tj 42.857143 0 0 42.857143 0 943 Tm 7.56 0 Td 66.111111 Tz (tacctgcgct ) Tj 4.48 0 Td 66.5 Tz (ccgtgcacga ) Tj 4.48 0 Td 66.5 Tz (caagagccag ) Tj 4.456667 0 Td 66.5 Tz (ggcggcaact ) Tj 4.503333 0 Td 66.5 Tz (tcgtcgagct ) Tj 4.503333 0 Td 66.5 Tz (aagcgccgac ) Tj 28.571429 0 0 28.571429 0 945 Tm 53.585 0 Td 91.388889 Tz (120 ) Tj 42.857143 0 0 42.857143 0 879 Tm 7.56 0 Td 66.5 Tz (aacgacggag ) Tj 4.456667 0 Td 66.888889 Tz (gcgtcatgaa ) Tj 4.503333 0 Td 66.111111 Tz (cccacgctgc ) Tj 4.48 0 Td 66.111111 Tz (agattctacc ) Tj 4.48 0 Td 66.5 Tz (tggaggcgtc ) Tj 4.503333 0 Td 66.5 Tz (caaggagcac ) Tj 28.571429 0 0 28.571429 0 881 Tm 53.55 0 Td 91.388889 Tz (180 ) Tj 42.857143 0 0 42.857143 0 811 Tm 7.536667 0 Td 66.888889 Tz (gacgggctcg ) Tj 4.503333 0 Td 66.5 Tz (ttcacgtcag ) Tj 4.48 0 Td 66.111111 Tz (atgttgctac ) Tj 4.48 0 Td 66.111111 Tz (aacaacaagt ) Tj 4.48 0 Td 66.5 Tz (actgggcgcc ) Tj 4.48 0 Td 66.888889 Tz (gcagcagcgc ) Tj 30 0 0 30 0 812 Tm 51 0 Td 88.888889 Tz (240 ) Tj 42.857143 0 0 42.857143 0 745 Tm 7.56 0 Td 66.5 Tz (ctgcttcacg ) Tj 4.456667 0 Td 66.888889 Tz (gcagcgctcg ) Tj 4.503333 0 Td 66.111111 Tz (ctggaccatt ) Tj 4.456667 0 Td 66.888889 Tz (ggtaccgcaa ) Tj 4.503333 0 Td 66.888889 Tz (atgagctgga ) Tj 4.48 0 Td 66.888889 Tz (ggaggatctc ) Tj 28.571429 0 0 28.571429 0 748 Tm 53.515 0 Td 93.333333 Tz (300 ) Tj 44.285714 0 0 44.285714 0 676 Tm 7.316129 0 Td 63.978495 Tz (tccaagccat ) Tj 4.335484 0 Td 63.978495 Tz (catgcaccct ) Tj 4.312903 0 Td 64.354839 Tz (gtttaagcac ) Tj 4.358065 0 Td 63.978495 Tz (atccccgtct ) Tj 4.335484 0 Td 64.731183 Tz (cgggcgagga ) Tj 4.358065 0 Td 64.354839 Tz (cggctccacc ) Tj 28.571429 0 0 28.571429 0 678 Tm 53.55 0 Td 93.333333 Tz (360 ) Tj 44.285714 0 0 44.285714 0 604.835603 Tm 7.316129 0 Td 63.978495 Tz (tgcaggttcc ) Tj 4.335484 0 Td 64.354839 Tz (ttcattccca ) Tj 4.312903 0 Td 64.731183 Tz (getaggaaaa ) Tj 4.358065 0 Td 64.354839 Tz (tatgottgcg ) Tj 4.335484 0 Td 64.731183 Tz (tgctatccag ) Tj 4.358065 0 Td 64.731183 Tz (ttctgatatg ) Tj 31.428571 0 0 31.428571 0 608 Tm 48.681818 0 Td 84.848485 Tz (420 ) Tj 41.428571 0 0 41.428571 0 535 Tm 7.82069 0 Td 68.390805 Tz (tccaagcacc ) Tj 4.634483 0 Td 68.793103 Tz (cctacttgca ) Tj 4.634483 0 Td 68.390805 Tz (tatagcacgt ) Tj 4.610345 0 Td 69.195402 Tz (gaagaatctg ) Tj 4.658621 0 Td 69.195402 Tz (atcaagataa ) Tj 4.658621 0 Td 68.793103 Tz (tctccttgat ) Tj 31.428571 0 0 31.428571 0 537 Tm 48.681818 0 Td 84.848485 Tz (480 ) Tj 42.857143 0 0 42.857143 0 464 Tm 7.536667 0 Td 66.888889 Tz (gcttttactg ) Tj 4.503333 0 Td 66.111111 Tz (tccttgatgt ) Tj 4.456667 0 Td 66.888889 Tz (gtcagaacag ) Tj 4.503333 0 Td 66.111111 Tz (atgcagttgc ) Tj 4.48 0 Td 66.5 Tz (ctagttatct ) Tj 4.503333 0 Td 66.888889 Tz (tgctttcaaa ) Tj 32.857143 0 0 32.857143 0 464 Tm 46.595652 0 Td 79.468599 Tz (540 ) Tj 45.714286 0 0 45.714286 0 394 Tm 7.065625 0 Td 62.708333 Tz (ggcgacaatg ) Tj 4.2 0 Td 62.34375 Tz (ggaggttcct ) Tj 4.221875 0 Td 62.34375 Tz (tggtgcgaag ) Tj 4.2 0 Td 62.34375 Tz (atcgtcgagg ) Tj 4.178125 0 Td 63.072917 Tz (gttatagata ) Tj 4.24375 0 Td 62.34375 Tz (tcttgaatac ) Tj 30 0 0 30 0 396 Tm 51.033333 0 Td 87.037037 Tz (600 ) Tj 41.428571 0 0 41.428571 0 322.996109 Tm 7.82069 0 Td 68.793103 Tz (tccaaagatg ) Tj 4.634483 0 Td 68.793103 Tz (atattggaga ) Tj 4.634483 0 Td 68.793103 Tz (tetaagtgtg ) Tj 4.634483 0 Td 68.793103 Tz (ttgcacacaa ) Tj 4.634483 0 Td 69.195402 Tz (ttttcaccaa ) Tj 4.658621 0 Td 69.195402 Tz (taaagatgga ) Tj 31.428571 0 0 31.428571 0 325 Tm 48.713636 0 Td 83.080808 Tz (660 ) Tj 44.285714 0 0 44.285714 0 250.834469 Tm 7.293548 0 Td 64.731183 Tz (gttgtccgta ) Tj 4.358065 0 Td 64.354839 Tz (taaaatccaa ) Tj 4.335484 0 Td 63.978495 Tz (ctatttcgac ) Tj 4.335484 0 Td 64.354839 Tz (atgttttgga ) Tj 4.312903 0 Td 64.731183 Tz (ggcgaagccc ) Tj 4.380645 0 Td 64.354839 Tz (aaattggato ) Tj 31.428571 0 0 31.428571 0 254 Tm 48.713636 0 Td 83.080808 Tz (720 ) Tj ET Q endstream endobj 201 0 obj << /Length 1 >> stream q endstream endobj 202 0 obj << /Length 19374 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.486111 0 Td 77.777778 Tz (33 ) Tj 54.285714 0 0 54.285714 0 2971 Tm 31.665789 0 Td 73.684211 Tz (34 ) Tj 46.428571 0 0 46.428571 0 2908.056604 Tm 24.36 0 Td 43.076923 Tz (- ) Tj 0.430769 0 Td 79.77208 Tz (continued ) Tj 45.714286 0 0 45.714286 0 2837.66439 Tm 7.0875 0 Td 61.979167 Tz (tgggctgatt ) Tj 4.2 0 Td 61.979167 Tz (caactgacac ) Tj 4.2 0 Td 61.979167 Tz (cacccacaac ) Tj 4.2 0 Td 62.34375 Tz (aaccgtgata ) Tj 4.2 0 Td 62.708333 Tz (cattattcaa ) Tj 4.2 0 Td 62.708333 Tz (ggtgaccact ) Tj 28.571429 0 0 28.571429 0 2843 Tm 53.585 0 Td 91.388889 Tz (780 ) Tj 47.142857 0 0 47.142857 0 2774 Tm 6.851515 0 Td 60.454545 Tz (gggcccgact ) Tj 4.093939 0 Td 60.10101 Tz (tcattgctct ) Tj 4.051515 0 Td 60.808081 Tz (gcgaaacttg ) Tj 4.072727 0 Td 60.808081 Tz (ggcaacaaca ) Tj 4.093939 0 Td 60.808081 Tz (atttctgcaa ) Tj 4.093939 0 Td 60.454545 Tz (aaggttaacc ) Tj 31.428571 0 0 31.428571 0 2776 Tm 48.681818 0 Td 83.080808 Tz (840 ) Tj 44.285714 0 0 44.285714 0 2708 Tm 7.316129 0 Td 64.354839 Tz (acagaaggga ) Tj 4.335484 0 Td 64.354839 Tz (agtatgattg ) Tj 4.335484 0 Td 63.978495 Tz (cctcaatgct ) Tj 4.312903 0 Td 64.354839 Tz (gctgttggtt ) Tj 4.358065 0 Td 64.354839 Tz (ccatcacagc ) Tj 4.358065 0 Td 64.731183 Tz (tgaagtaaaa ) Tj 28.571429 0 0 28.571429 0 2711 Tm 53.55 0 Td 91.388889 Tz (900 ) Tj 42.857143 0 0 42.857143 0 2641 Tm 7.56 0 Td 66.5 Tz (atgcggtgca ) Tj 4.48 0 Td 66.111111 Tz (ttgaaccaat ) Tj 4.48 0 Td 66.5 Tz (tgtttctcga ) Tj 4.456667 0 Td 66.888889 Tz (gacatctatg ) Tj 4.503333 0 Td 66.5 Tz (atgttgattt ) Tj 4.503333 0 Td 66.5 Tz (tcgcctaggt ) Tj 27.142857 0 0 27.142857 0 2645 Tm 56.405263 0 Td 96.19883 Tz (960 ) Tj 44.285714 0 0 44.285714 0 2573.837864 Tm 7.293548 0 Td 64.731183 Tz (gaagctaaga ) Tj 4.358065 0 Td 64.354839 Tz (tctacaccaa ) Tj 4.335484 0 Td 64.354839 Tz (tggtattgag ) Tj 4.312903 0 Td 64.731183 Tz (ggccttgata ) Tj 4.335484 0 Td 64.731183 Tz (gtcaaattgt ) Tj 4.380645 0 Td 64.731183 Tz (tgaaaacatg ) Tj 32.857143 0 0 32.857143 0 2575 Tm 45.986957 0 Td 84.963768 Tz (1020 ) Tj 28.571429 0 0 28.571429 0 2510 Tm 11.34 0 Td 99.75 Tz (accaccacaa ) Tj 44.285714 0 0 44.285714 0 2506.201641 Tm 11.651613 0 Td 63.978495 Tz (caaacaaaac ) Tj 4.335484 0 Td 63.978495 Tz (caaaatgatc ) Tj 4.335484 0 Td 64.354839 Tz (ttcacataca ) Tj 4.335484 0 Td 64.354839 Tz (caaataccgt ) Tj 4.358065 0 Td 64.354839 Tz (ccagagtacc ) Tj 28.571429 0 0 28.571429 0 2511 Tm 52.955 0 Td 94.791667 Tz (1080 ) Tj 41.428571 0 0 41.428571 0 2441.000974 Tm 7.82069 0 Td 68.793103 Tz (tggagttcta ) Tj 4.634483 0 Td 68.390805 Tz (ctgtttcatt ) Tj 4.610345 0 Td 68.793103 Tz (gaagattggc ) Tj 4.634483 0 Td 69.195402 Tz (gtcaagacca ) Tj 4.658621 0 Td 68.793103 Tz (aatttaaatc ) Tj 4.658621 0 Td 69.195402 Tz (cgggattcca ) Tj 31.428571 0 0 31.428571 0 2442 Tm 48.140909 0 Td 86.174242 Tz (1140 ) Tj 42.857143 0 0 42.857143 0 2376 Tm 7.56 0 Td 66.5 Tz (tttgtagttg ) Tj 4.48 0 Td 66.111111 Tz (acggcgaagt ) Tj 4.48 0 Td 66.111111 Tz (tgaggtcagc ) Tj 4.48 0 Td 66.5 Tz (actgagttta ) Tj 4.456667 0 Td 67.277778 Tz (gtggatcata ) Tj 4.526667 0 Td 66.888889 Tz (tacctggggg ) Tj 31.428571 0 0 31.428571 0 2378 Tm 48.109091 0 Td 86.174242 Tz (1200 ) Tj 42.857143 0 0 42.857143 0 2309 Tm 7.536667 0 Td 66.5 Tz (ggagccaaat ) Tj 4.503333 0 Td 66.5 Tz (?tgacacaaa ) Tj 4.48 0 Td 66.111111 Tz (agtagtaagc ) Tj 4.48 0 Td 66.5 Tz (aaacaaattg ) Tj 4.48 0 Td 66.5 Tz (atgttgaagt ) Tj 4.503333 0 Td 66.888889 Tz (tcctccaatg ) Tj 28.571429 0 0 28.571429 0 2311 Tm 52.955 0 Td 94.791667 Tz (1260 ) Tj 48.571429 0 0 48.571429 0 2240.833333 Tm 6.670588 0 Td 58.676471 Tz (aagaaagtga ) Tj 3.952941 0 Td 58.333333 Tz (cagtaaaagc ) Tj 3.932353 0 Td 59.019608 Tz (gattggatca ) Tj 3.973529 0 Td 58.333333 Tz (aacggtttat ) Tj 3.932353 0 Td 59.019608 Tz (gtgatatacc ) Tj 3.994118 0 Td 58.676471 Tz (tttctcatac ) Tj 30 0 0 30 0 2246 Tm 50.4 0 Td 90.277778 Tz (1320 ) Tj 42.857143 0 0 42.857143 0 2175.004878 Tm 7.56 0 Td 66.5 Tz (aagcagaggg ) Tj 4.48 0 Td 66.111111 Tz (atattctaac ) Tj 4.48 0 Td 66.111111 Tz (caatggagat ) Tj 4.456667 0 Td 66.5 Tz (gaagttatcc ) Tj 4.503333 0 Td 66.5 Tz (aagaattcac ) Tj 4.503333 0 Td 66.888889 Tz (cgatggcatg ) Tj 34.285714 0 0 34.285714 0 2176 Tm 44.1 0 Td 78.993056 Tz (1380 ) Tj 42.857143 0 0 42.857143 0 2106.899384 Tm 7.56 0 Td 66.5 Tz (tattttggtg ) Tj 4.48 0 Td 66.111111 Tz (ttaaaacctc ) Tj 4.48 0 Td 66.5 Tz (cagcatcacg ) Tj 4.48 0 Td 66.5 Tz (ttccatacca ) Tj 4.48 0 Td 66.888889 Tz (aagaagaaca ) Tj 4.503333 0 Td 66.111111 Tz (cctgtga ) Tj 30 0 0 30 0 2112 Tm 50.433333 0 Td 90.277778 Tz (1437 ) Tj 38.571429 0 0 38.571429 0 2007 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.4 0 Td 51.851852 Tz (3 ) Tj 31.428571 0 0 31.428571 0 1977 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 83.080808 Tz (478 ) Tj 31.428571 0 0 31.428571 0 1943 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 86.616162 Tz (PRT ) Tj 34.285714 0 0 34.285714 0 1910 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (213 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.933333 0 Td 79.600694 Tz (ORGANISM ) Tj 4.229167 0 Td 24.305556 Tz (: ) Tj 0.875 0 Td 83.854167 Tz (Triticum ) Tj 4.608333 0 Td 83.246528 Tz (aestivum ) Tj 37.619048 0 0 37.619048 0 1840.636771 Tm 8.612658 0 Td 53.164557 Tz (< ) Tj 0.478481 0 Td 69.409283 Tz (400 ) Tj 1.435443 0 Td 53.164557 Tz (> ) Tj 0.877215 0 Td 75.316456 Tz (SEQUENCE ) Tj 3.85443 0 Td 17.721519 Tz (: ) Tj 0.770886 0 Td 53.164557 Tz (3 ) Tj 45.714286 0 0 45.714286 0 1771.754408 Tm 7.065625 0 Td 59.548611 Tz (Met ) Tj 1.553125 0 Td 59.548611 Tz (Phe ) Tj 1.53125 0 Td 59.548611 Tz (Pro ) Tj 1.53125 0 Td 60.763889 Tz (Leu ) Tj 1.509375 0 Td 59.548611 Tz (Ser ) Tj 1.4875 0 Td 61.979167 Tz (Ala ) Tj 1.575 0 Td 60.763889 Tz (Leu ) Tj 1.53125 0 Td 59.548611 Tz (Pro ) Tj 1.4875 0 Td 61.979167 Tz (Arg ) Tj 1.575 0 Td 58.333333 Tz (Cys ) Tj 1.4875 0 Td 59.548611 Tz (Val ) Tj 1.509375 0 Td 61.979167 Tz (Ala ) Tj 1.575 0 Td 60.763889 Tz (Leu ) Tj 1.4875 0 Td 63.194444 Tz (Arg ) Tj 1.596875 0 Td 59.548611 Tz (Ser ) Tj 1.53125 0 Td 58.333333 Tz (Lys ) Tj 27.142857 0 0 27.142857 0 1746 Tm 11.973684 0 Td 73.684211 Tz (1 ) Tj 27.142857 0 0 27.142857 0 1747 Tm 22.252632 0 Td 73.684211 Tz (5 ) Tj 28.571429 0 0 28.571429 0 1747 Tm 33.355 0 Td 84.583333 Tz (10 ) Tj 31.428571 0 0 31.428571 0 1745 Tm 41.490909 0 Td 76.893939 Tz (15 ) Tj 45.714286 0 0 45.714286 0 1673.07125 Tm 7.065625 0 Td 59.548611 Tz (His ) Tj 1.53125 0 Td 61.979167 Tz (Gly ) Tj 1.509375 0 Td 63.194444 Tz (Asn ) Tj 1.575 0 Td 59.548611 Tz (Ser ) Tj 1.509375 0 Td 59.548611 Tz (Tyr ) Tj 1.53125 0 Td 60.763889 Tz (Leu ) Tj 1.4875 0 Td 61.979167 Tz (Arg ) Tj 1.575 0 Td 59.548611 Tz (Ser ) Tj 1.4875 0 Td 60.763889 Tz (Val ) Tj 1.553125 0 Td 59.548611 Tz (His ) Tj 1.509375 0 Td 60.763889 Tz (Asp ) Tj 1.553125 0 Td 58.333333 Tz (Lys ) Tj 1.53125 0 Td 59.548611 Tz (Ser ) Tj 1.509375 0 Td 63.194444 Tz (Gin ) Tj 1.553125 0 Td 61.979167 Tz (Gly ) Tj 1.53125 0 Td 61.979167 Tz (Gly ) Tj 34.285714 0 0 34.285714 0 1644 Tm 15.545833 0 Td 77.777778 Tz (20 ) Tj 32.857143 0 0 32.857143 0 1644 Tm 26.843478 0 Td 78.623188 Tz (25 ) Tj 32.857143 0 0 32.857143 0 1644 Tm 37.495652 0 Td 76.086957 Tz (30 ) Tj 42.857143 0 0 42.857143 0 1571.507426 Tm 7.513333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Phe ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 64.814815 Tz (Gly ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 64.814815 Tz (Met ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Pro ) Tj 31.428571 0 0 31.428571 0 1544 Tm 25.868182 0 Td 79.545455 Tz (40 ) Tj 30 0 0 30 0 1544 Tm 38.7 0 Td 83.333333 Tz (45 ) Tj 34.285714 0 0 34.285714 0 1543 Tm 13.533333 0 Td 75.347222 Tz (35 ) Tj 44.285714 0 0 44.285714 0 1474.066333 Tm 7.270968 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 60.215054 Tz (Cys ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 61.469534 Tz (Phe ) Tj 1.558065 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 63.978495 Tz (Glu ) Tj 1.558065 0 Td 63.978495 Tz (Ala ) Tj 1.625806 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.558065 0 Td 62.724014 Tz (Glu ) Tj 1.558065 0 Td 61.469534 Tz (His ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.603226 0 Td 65.232975 Tz (Gly ) Tj 1.625806 0 Td 62.724014 Tz (Leu ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 30 0 0 30 0 1445 Tm 13.166667 0 Td 80.555556 Tz (50 ) Tj 30 0 0 30 0 1445 Tm 24.766667 0 Td 83.333333 Tz (55 ) Tj 30 0 0 30 0 1445 Tm 36.4 0 Td 83.333333 Tz (60 ) Tj 42.857143 0 0 42.857143 0 1374.947368 Tm 7.536667 0 Td 63.518519 Tz (His ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 62.222222 Tz (Cys ) Tj 1.61 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 62.222222 Tz (Trp ) Tj 1.563333 0 Td 66.111111 Tz (Ala ) Tj 1.68 0 Td 63.518519 Tz (Pro ) Tj 1.61 0 Td 67.407407 Tz (Gin ) Tj 1.656667 0 Td 66.111111 Tz (Gin ) Tj 1.61 0 Td 66.111111 Tz (Arg ) Tj 31.428571 0 0 31.428571 0 1345 Tm 10.309091 0 Td 82.19697 Tz (65 ) Tj 30 0 0 30 0 1345 Tm 22.466667 0 Td 83.333333 Tz (70 ) Tj 31.428571 0 0 31.428571 0 1346 Tm 32.518182 0 Td 79.545455 Tz (75 ) Tj 34.285714 0 0 34.285714 0 1344 Tm 40.045833 0 Td 75.347222 Tz (80 ) Tj 41.428571 0 0 41.428571 0 1273.505618 Tm 7.82069 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 67.049808 Tz (Leu ) Tj 1.665517 0 Td 65.708812 Tz (His ) Tj 1.689655 0 Td 68.390805 Tz (Gly ) Tj 1.689655 0 Td 65.708812 Tz (Ser ) Tj 1.641379 0 Td 68.390805 Tz (Ala ) Tj 1.689655 0 Td 68.390805 Tz (Arg ) Tj 1.737931 0 Td 65.708812 Tz (Trp ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.713793 0 Td 64.367816 Tz (Ile ) Tj 1.641379 0 Td 67.049808 Tz (Gly ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 68.390805 Tz (Ala ) Tj 1.689655 0 Td 71.072797 Tz (Asn ) Tj 1.737931 0 Td 68.390805 Tz (Glu ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 28.571429 0 0 28.571429 0 1247 Tm 21.105 0 Td 87.5 Tz (85 ) Tj 27.142857 0 0 27.142857 0 1248 Tm 35.110526 0 Td 89.035088 Tz (90 ) Tj 28.571429 0 0 28.571429 0 1247 Tm 45.605 0 Td 84.583333 Tz (95 ) Tj 42.857143 0 0 42.857143 0 1172.484772 Tm 7.536667 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Pro ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 63.518519 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 64.814815 Tz (His ) Tj 1.703333 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Pro ) Tj 34.285714 0 0 34.285714 0 1144 Tm 15.575 0 Td 77.777778 Tz (100 ) Tj 30 0 0 30 0 1146 Tm 29.433333 0 Td 87.037037 Tz (105 ) Tj 30 0 0 30 0 1145 Tm 41.1 0 Td 88.888889 Tz (110 ) Tj 44.285714 0 0 44.285714 0 1073.210526 Tm 7.270968 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 61.469534 Tz (Ser ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.580645 0 Td 63.978495 Tz (Glu ) Tj 1.535484 0 Td 63.978495 Tz (Asp ) Tj 1.603226 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 60.215054 Tz (Cys ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 60.215054 Tz (Phe ) Tj 1.558065 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 61.469534 Tz (His ) Tj 1.603226 0 Td 62.724014 Tz (Ser ) Tj 1.580645 0 Td 63.978495 Tz (Gin ) Tj 1.603226 0 Td 62.724014 Tz (Leu ) Tj 30 0 0 30 0 1047 Tm 15.466667 0 Td 87.037037 Tz (115 ) Tj 31.428571 0 0 31.428571 0 1045 Tm 25.9 0 Td 83.080808 Tz (120 ) Tj 34.285714 0 0 34.285714 0 1044 Tm 33.920833 0 Td 76.157407 Tz (125 ) Tj 48.571429 0 0 48.571429 0 973.617237 Tm 6.65 0 Td 58.333333 Tz (Gly ) Tj 1.461765 0 Td 54.901961 Tz (Lys ) Tj 1.441176 0 Td 56.045752 Tz (Tyr ) Tj 1.4 0 Td 58.333333 Tz (Ala ) Tj 1.461765 0 Td 54.901961 Tz (Cys ) Tj 1.4 0 Td 57.189542 Tz (Val ) Tj 1.482353 0 Td 57.189542 Tz (Leu ) Tj 1.441176 0 Td 56.045752 Tz (Ser ) Tj 1.441176 0 Td 56.045752 Tz (Ser ) Tj 1.441176 0 Td 56.045752 Tz (Ser ) Tj 1.4 0 Td 57.189542 Tz (Asp ) Tj 1.441176 0 Td 56.045752 Tz (Met ) Tj 1.461765 0 Td 56.045752 Tz (Ser ) Tj 1.441176 0 Td 56.045752 Tz (Lys ) Tj 1.441176 0 Td 56.045752 Tz (His ) Tj 1.461765 0 Td 56.045752 Tz (Pro ) Tj 28.571429 0 0 28.571429 0 947 Tm 13.79 0 Td 91.388889 Tz (130 ) Tj 28.571429 0 0 28.571429 0 947 Tm 26.005 0 Td 91.388889 Tz (135 ) Tj 30 0 0 30 0 945 Tm 36.433333 0 Td 87.037037 Tz (140 ) Tj 42.857143 0 0 42.857143 0 873.885714 Tm 7.56 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.54 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.656667 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 64.814815 Tz (Gin ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 66.111111 Tz (Leu ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 31.428571 0 0 31.428571 0 846 Tm 10.340909 0 Td 83.080808 Tz (145 ) Tj 30 0 0 30 0 847 Tm 22.433333 0 Td 87.037037 Tz (150 ) Tj 30 0 0 30 0 847 Tm 34.066667 0 Td 87.037037 Tz (155 ) Tj 31.428571 0 0 31.428571 0 846 Tm 43.718182 0 Td 81.313131 Tz (160 ) Tj 41.428571 0 0 41.428571 0 772.75188 Tm 7.772414 0 Td 68.390805 Tz (Ala ) Tj 1.737931 0 Td 65.708812 Tz (Phe ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.689655 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 65.708812 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Glu ) Tj 1.689655 0 Td 68.390805 Tz (Gin ) Tj 1.689655 0 Td 64.367816 Tz (Met ) Tj 1.665517 0 Td 68.390805 Tz (Gln ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 67.049808 Tz (Pro ) Tj 1.713793 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 65.708812 Tz (Tyr ) Tj 31.428571 0 0 31.428571 0 747 Tm 19.218182 0 Td 83.080808 Tz (165 ) Tj 32.857143 0 0 32.857143 0 745 Tm 29.034783 0 Td 77.777778 Tz (170 ) Tj 34.285714 0 0 34.285714 0 746 Tm 38.004167 0 Td 79.398148 Tz (175 ) Tj 41.428571 0 0 41.428571 0 673.636704 Tm 7.82069 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Ala ) Tj 1.737931 0 Td 65.708812 Tz (Phe ) Tj 1.689655 0 Td 64.367816 Tz (Lys ) Tj 1.641379 0 Td 68.390805 Tz (Gly ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 1.689655 0 Td 69.731801 Tz (Asn ) Tj 1.713793 0 Td 68.390805 Tz (Gly ) Tj 1.665517 0 Td 68.390805 Tz (Arg ) Tj 1.737931 0 Td 65.708812 Tz (Phe ) Tj 1.689655 0 Td 65.708812 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Gly ) Tj 1.665517 0 Td 68.390805 Tz (Ala ) Tj 1.737931 0 Td 65.708812 Tz (Lys ) Tj 1.737931 0 Td 64.367816 Tz (Ile ) Tj 1.617241 0 Td 67.049808 Tz (Val ) Tj 35.714286 0 0 35.714286 0 640 Tm 14.952 0 Td 74.666667 Tz (180 ) Tj 32.857143 0 0 32.857143 0 642 Tm 26.873913 0 Td 79.468599 Tz (185 ) Tj 34.285714 0 0 34.285714 0 642 Tm 35.933333 0 Td 81.018519 Tz (190 ) Tj 42.857143 0 0 42.857143 0 567.7575 Tm 7.536667 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 66.111111 Tz (Arg ) Tj 1.656667 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.586667 0 Td 64.814815 Tz (Asp ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.703333 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 67.407407 Tz (Gly ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 35.714286 0 0 35.714286 0 535 Tm 12.964 0 Td 74.666667 Tz (195 ) Tj 31.428571 0 0 31.428571 0 537 Tm 25.836364 0 Td 84.848485 Tz (200 ) Tj 35.714286 0 0 35.714286 0 535 Tm 32.508 0 Td 74.666667 Tz (205 ) Tj 42.857143 0 0 42.857143 0 460.511335 Tm 7.56 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.656667 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.586667 0 Td 64.814815 Tz (Asp ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Arg ) Tj 1.703333 0 Td 62.222222 Tz (Ile ) Tj 28.571429 0 0 28.571429 0 431 Tm 13.79 0 Td 93.333333 Tz (210 ) Tj 30 0 0 30 0 430 Tm 24.766667 0 Td 88.888889 Tz (215 ) Tj 32.857143 0 0 32.857143 0 429 Tm 33.234783 0 Td 81.15942 Tz (220 ) Tj 41.428571 0 0 41.428571 0 354.622166 Tm 7.82069 0 Td 64.367816 Tz (Lys ) Tj 1.689655 0 Td 65.708812 Tz (Ser ) Tj 1.641379 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 65.708812 Tz (Tyr ) Tj 1.665517 0 Td 65.708812 Tz (Phe ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.713793 0 Td 65.708812 Tz (Met ) Tj 1.713793 0 Td 65.708812 Tz (Phe ) Tj 1.689655 0 Td 65.708812 Tz (Trp ) Tj 1.641379 0 Td 68.390805 Tz (Arg ) Tj 1.689655 0 Td 67.049808 Tz (Arg ) Tj 1.713793 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 65.708812 Tz (Pro ) Tj 1.641379 0 Td 71.072797 Tz (Asn ) Tj 1.762069 0 Td 65.708812 Tz (Trp ) Tj 1.713793 0 Td 64.367816 Tz (Ile ) Tj 32.857143 0 0 32.857143 0 325 Tm 9.830435 0 Td 81.15942 Tz (225 ) Tj 34.285714 0 0 34.285714 0 323 Tm 19.629167 0 Td 77.777778 Tz (230 ) Tj 30 0 0 30 0 325 Tm 34.066667 0 Td 88.888889 Tz (235 ) Tj 31.428571 0 0 31.428571 0 325 Tm 43.686364 0 Td 83.080808 Tz (240 ) Tj 42.857143 0 0 42.857143 0 248.895131 Tm 7.56 0 Td 63.518519 Tz (Trp ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.61 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 66.111111 Tz (Asn ) Tj 1.61 0 Td 66.111111 Tz (Arg ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 64.814815 Tz (Thr ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 30 0 0 30 0 220 Tm 20.066667 0 Td 88.888889 Tz (245 ) Tj 28.571429 0 0 28.571429 0 220 Tm 33.355 0 Td 91.388889 Tz (250 ) Tj 28.571429 0 0 28.571429 0 221 Tm 45.57 0 Td 93.333333 Tz (255 ) Tj ET Q endstream endobj 203 0 obj << /Length 1 >> stream q endstream endobj 204 0 obj << /Length 18079 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3028 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 75.714286 0 0 75.714286 0 2963 Tm 9.826415 0 Td 58.333333 Tz (35 ) Tj 55.714286 0 0 55.714286 0 2971 Tm 30.853846 0 Td 71.794872 Tz (36 ) Tj 47.142857 0 0 47.142857 0 2908 Tm 23.990909 0 Td 42.424242 Tz (- ) Tj 0.424242 0 Td 78.563412 Tz (continued ) Tj 41.428571 0 0 41.428571 0 2803.88764 Tm 7.82069 0 Td 64.367816 Tz (Lys ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 68.390805 Tz (Gly ) Tj 1.713793 0 Td 65.708812 Tz (Pro ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 65.708812 Tz (Phe ) Tj 1.713793 0 Td 64.367816 Tz (Ile ) Tj 1.617241 0 Td 68.390805 Tz (Ala ) Tj 1.737931 0 Td 65.708812 Tz (Leu ) Tj 1.617241 0 Td 68.390805 Tz (Arg ) Tj 1.689655 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 68.390805 Tz (Leu ) Tj 1.689655 0 Td 68.390805 Tz (Gly ) Tj 1.665517 0 Td 69.731801 Tz (Asn ) Tj 31.428571 0 0 31.428571 0 2776 Tm 16.990909 0 Td 83.080808 Tz (260 ) Tj 30 0 0 30 0 2776 Tm 29.433333 0 Td 88.888889 Tz (265 ) Tj 28.571429 0 0 28.571429 0 2778 Tm 43.085 0 Td 95.277778 Tz (270 ) Tj 42.857143 0 0 42.857143 0 2704.969849 Tm 7.513333 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.61 0 Td 62.222222 Tz (Lys ) Tj 1.586667 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 64.814815 Tz (Gly ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 67.407407 Tz (Asp ) Tj 1.703333 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 34.285714 0 0 34.285714 0 2676 Tm 13.504167 0 Td 77.777778 Tz (275 ) Tj 34.285714 0 0 34.285714 0 2676 Tm 23.683333 0 Td 77.777778 Tz (280 ) Tj 32.857143 0 0 32.857143 0 2675 Tm 35.334783 0 Td 81.15942 Tz (285 ) Tj 44.285714 0 0 44.285714 0 2603.747804 Tm 7.270968 0 Td 65.232975 Tz (Asn ) Tj 1.580645 0 Td 63.978495 Tz (Ala ) Tj 1.580645 0 Td 63.978495 Tz (Ala ) Tj 1.580645 0 Td 62.724014 Tz (Val ) Tj 1.580645 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 61.469534 Tz (Ser ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.558065 0 Td 61.469534 Tz (Thr ) Tj 1.535484 0 Td 63.978495 Tz (Ala ) Tj 1.603226 0 Td 63.978495 Tz (Glu ) Tj 1.558065 0 Td 61.469534 Tz (Val ) Tj 1.603226 0 Td 60.215054 Tz (Lys ) Tj 1.558065 0 Td 61.469534 Tz (Met ) Tj 1.558065 0 Td 65.232975 Tz (Arg ) Tj 1.648387 0 Td 60.215054 Tz (Cys ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 30 0 0 30 0 2576 Tm 13.133333 0 Td 88.888889 Tz (290 ) Tj 28.571429 0 0 28.571429 0 2578 Tm 25.97 0 Td 93.333333 Tz (295 ) Tj 31.428571 0 0 31.428571 0 2576 Tm 34.745455 0 Td 84.848485 Tz (300 ) Tj 45.714286 0 0 45.714286 0 2505.118899 Tm 7.065625 0 Td 61.979167 Tz (Glu ) Tj 1.553125 0 Td 59.548611 Tz (Pro ) Tj 1.553125 0 Td 58.333333 Tz (Ile ) Tj 1.465625 0 Td 60.763889 Tz (Val ) Tj 1.553125 0 Td 59.548611 Tz (Ser ) Tj 1.4875 0 Td 61.979167 Tz (Arg ) Tj 1.53125 0 Td 61.979167 Tz (Asp ) Tj 1.596875 0 Td 58.333333 Tz (Ile ) Tj 1.509375 0 Td 59.548611 Tz (Tyr ) Tj 1.4875 0 Td 61.979167 Tz (Asp ) Tj 1.53125 0 Td 59.548611 Tz (Val ) Tj 1.509375 0 Td 61.979167 Tz (Asp ) Tj 1.575 0 Td 59.548611 Tz (Phe ) Tj 1.4875 0 Td 63.194444 Tz (Arg ) Tj 1.596875 0 Td 60.763889 Tz (Leu ) Tj 1.509375 0 Td 61.979167 Tz (Gly ) Tj 31.428571 0 0 31.428571 0 2476 Tm 10.309091 0 Td 84.848485 Tz (305 ) Tj 35.714286 0 0 35.714286 0 2476 Tm 18.788 0 Td 77.777778 Tz (310 ) Tj 32.857143 0 0 32.857143 0 2476 Tm 31.104348 0 Td 81.15942 Tz (315 ) Tj 34.285714 0 0 34.285714 0 2476 Tm 40.016667 0 Td 79.398148 Tz (320 ) Tj 42.857143 0 0 42.857143 0 2405.87218 Tm 7.536667 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Ala ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.656667 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 64.814815 Tz (Gly ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 64.814815 Tz (Ser ) Tj 1.633333 0 Td 66.111111 Tz (Gln ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 32.857143 0 0 32.857143 0 2376 Tm 18.352174 0 Td 81.15942 Tz (325 ) Tj 30 0 0 30 0 2379 Tm 31.733333 0 Td 87.037037 Tz (330 ) Tj 30 0 0 30 0 2378 Tm 43.433333 0 Td 88.888889 Tz (335 ) Tj 40 0 0 40 0 2304.729114 Tm 8.05 0 Td 69.444444 Tz (Val ) Tj 1.775 0 Td 70.833333 Tz (Glu ) Tj 1.725 0 Td 72.222222 Tz (Asn ) Tj 1.775 0 Td 68.055556 Tz (Met ) Tj 1.75 0 Td 68.055556 Tz (Thr ) Tj 1.75 0 Td 68.055556 Tz (Thr ) Tj 1.75 0 Td 68.055556 Tz (Thr ) Tj 1.75 0 Td 68.055556 Tz (Thr ) Tj 1.7 0 Td 72.222222 Tz (Asn ) Tj 1.8 0 Td 66.666667 Tz (Lys ) Tj 1.75 0 Td 66.666667 Tz (Thr ) Tj 1.725 0 Td 66.666667 Tz (Lys ) Tj 1.725 0 Td 68.055556 Tz (Met ) Tj 1.8 0 Td 68.055556 Tz (Ile ) Tj 1.75 0 Td 68.055556 Tz (Phe ) Tj 1.75 0 Td 68.055556 Tz (Thr ) Tj 27.142857 0 0 27.142857 0 2279 Tm 19.673684 0 Td 96.19883 Tz (340 ) Tj 28.571429 0 0 28.571429 0 2278 Tm 30.905 0 Td 93.333333 Tz (345 ) Tj 32.857143 0 0 32.857143 0 2276 Tm 37.465217 0 Td 82.850242 Tz (350 ) Tj 42.857143 0 0 42.857143 0 2204.107459 Tm 7.56 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Thr ) Tj 1.563333 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Gin ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 63.518519 Tz (Trp ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Ser ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 64.814815 Tz (Ser ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 32.857143 0 0 32.857143 0 2176 Tm 14.121739 0 Td 81.15942 Tz (355 ) Tj 31.428571 0 0 31.428571 0 2178 Tm 25.868182 0 Td 84.848485 Tz (360 ) Tj 34.285714 0 0 34.285714 0 2176 Tm 33.8625 0 Td 77.777778 Tz (365 ) Tj 42.857143 0 0 42.857143 0 2107.261421 Tm 7.583333 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.68 0 Td 60.925926 Tz (Ile ) Tj 1.586667 0 Td 63.518519 Tz (Pro ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 1.586667 0 Td 66.111111 Tz (Val ) Tj 1.656667 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 32.857143 0 0 32.857143 0 2077 Tm 11.991304 0 Td 81.15942 Tz (370 ) Tj 32.857143 0 0 32.857143 0 2076 Tm 22.613043 0 Td 81.15942 Tz (375 ) Tj 32.857143 0 0 32.857143 0 2076 Tm 33.204348 0 Td 81.15942 Tz (380 ) Tj 48.571429 0 0 48.571429 0 2004.192982 Tm 6.65 0 Td 58.333333 Tz (Gly ) Tj 1.441176 0 Td 58.333333 Tz (Glu ) Tj 1.420588 0 Td 57.189542 Tz (Val ) Tj 1.461765 0 Td 58.333333 Tz (Glu ) Tj 1.4 0 Td 57.189542 Tz (Val ) Tj 1.482353 0 Td 56.045752 Tz (Ser ) Tj 1.441176 0 Td 56.045752 Tz (Thr ) Tj 1.420588 0 Td 58.333333 Tz (Glu ) Tj 1.461765 0 Td 56.045752 Tz (Phe ) Tj 1.441176 0 Td 56.045752 Tz (Ser ) Tj 1.420588 0 Td 57.189542 Tz (Gly ) Tj 1.441176 0 Td 56.045752 Tz (Ser ) Tj 1.441176 0 Td 56.045752 Tz (Tyr ) Tj 1.441176 0 Td 57.189542 Tz (Thr ) Tj 1.461765 0 Td 56.045752 Tz (Trp ) Tj 1.420588 0 Td 58.333333 Tz (Gly ) Tj 32.857143 0 0 32.857143 0 1976 Tm 9.830435 0 Td 81.15942 Tz (385 ) Tj 28.571429 0 0 28.571429 0 1979 Tm 23.52 0 Td 93.333333 Tz (390 ) Tj 28.571429 0 0 28.571429 0 1979 Tm 35.735 0 Td 93.333333 Tz (395 ) Tj 31.428571 0 0 31.428571 0 1976 Tm 43.686364 0 Td 83.080808 Tz (400 ) Tj 45.714286 0 0 45.714286 0 1905.615094 Tm 7.065625 0 Td 61.979167 Tz (Gly ) Tj 1.509375 0 Td 61.979167 Tz (Ala ) Tj 1.575 0 Td 58.333333 Tz (Lys ) Tj 1.53125 0 Td 59.548611 Tz (Ser ) Tj 1.465625 0 Td 61.979167 Tz (Asp ) Tj 1.575 0 Td 59.548611 Tz (Thr ) Tj 1.53125 0 Td 58.333333 Tz (Lys ) Tj 1.4875 0 Td 60.763889 Tz (Val ) Tj 1.53125 0 Td 60.763889 Tz (Val ) Tj 1.575 0 Td 59.548611 Tz (Ser ) Tj 1.53125 0 Td 57.118056 Tz (Lys ) Tj 1.4875 0 Td 61.979167 Tz (Gin ) Tj 1.575 0 Td 58.333333 Tz (Ile ) Tj 1.465625 0 Td 63.194444 Tz (Asp ) Tj 1.553125 0 Td 60.763889 Tz (Val ) Tj 1.553125 0 Td 61.979167 Tz (Glu ) Tj 28.571429 0 0 28.571429 0 1880 Tm 21.07 0 Td 93.333333 Tz (405 ) Tj 32.857143 0 0 32.857143 0 1877 Tm 28.973913 0 Td 79.468599 Tz (410 ) Tj 30 0 0 30 0 1879 Tm 43.433333 0 Td 88.888889 Tz (415 ) Tj 44.285714 0 0 44.285714 0 1805.174242 Tm 7.270968 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 61.469534 Tz (Pro ) Tj 1.580645 0 Td 61.469534 Tz (Pro ) Tj 1.558065 0 Td 61.469534 Tz (Met ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 61.469534 Tz (Thr ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 60.215054 Tz (Lys ) Tj 1.535484 0 Td 62.724014 Tz (Ala ) Tj 1.625806 0 Td 60.215054 Tz (Ile ) Tj 1.535484 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 62.724014 Tz (Ser ) Tj 1.558065 0 Td 65.232975 Tz (Asn ) Tj 1.603226 0 Td 63.978495 Tz (Gly ) Tj 30 0 0 30 0 1778 Tm 17.8 0 Td 87.037037 Tz (420 ) Tj 31.428571 0 0 31.428571 0 1778 Tm 28.095455 0 Td 84.848485 Tz (425 ) Tj 30 0 0 30 0 1779 Tm 41.033333 0 Td 90.740741 Tz (430 ) Tj 44.285714 0 0 44.285714 0 1706.62169 Tm 7.316129 0 Td 62.724014 Tz (Leu ) Tj 1.580645 0 Td 60.215054 Tz (Cys ) Tj 1.535484 0 Td 63.978495 Tz (Asp ) Tj 1.648387 0 Td 60.215054 Tz (Ile ) Tj 1.535484 0 Td 61.469534 Tz (Pro ) Tj 1.580645 0 Td 61.469534 Tz (Phe ) Tj 1.580645 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.558065 0 Td 63.978495 Tz (Gin ) Tj 1.558065 0 Td 62.724014 Tz (Arg ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.648387 0 Td 60.215054 Tz (Ile ) Tj 1.558065 0 Td 63.978495 Tz (Leu ) Tj 1.603226 0 Td 61.469534 Tz (Thr ) Tj 1.535484 0 Td 65.232975 Tz (Asn ) Tj 34.285714 0 0 34.285714 0 1676 Tm 13.504167 0 Td 79.398148 Tz (435 ) Tj 34.285714 0 0 34.285714 0 1676 Tm 23.683333 0 Td 79.398148 Tz (440 ) Tj 32.857143 0 0 32.857143 0 1677 Tm 35.334783 0 Td 82.850242 Tz (445 ) Tj 42.857143 0 0 42.857143 0 1605.269663 Tm 7.536667 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 66.111111 Tz (Gin ) Tj 1.633333 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 64.814815 Tz (Gly ) Tj 1.61 0 Td 63.518519 Tz (Met ) Tj 1.656667 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 64.814815 Tz (Phe ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 31.428571 0 0 31.428571 0 1577 Tm 12.536364 0 Td 84.848485 Tz (450 ) Tj 31.428571 0 0 31.428571 0 1577 Tm 23.640909 0 Td 84.848485 Tz (455 ) Tj 31.428571 0 0 31.428571 0 1577 Tm 34.745455 0 Td 84.848485 Tz (460 ) Tj 42.857143 0 0 42.857143 0 1505.837209 Tm 7.56 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.656667 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 64.814815 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 63.518519 Tz (His ) Tj 1.656667 0 Td 66.111111 Tz (Leu ) Tj 31.428571 0 0 31.428571 0 1478 Tm 10.277273 0 Td 84.848485 Tz (465 ) Tj 32.857143 0 0 32.857143 0 1478 Tm 20.482609 0 Td 81.15942 Tz (470 ) Tj 31.428571 0 0 31.428571 0 1479 Tm 32.486364 0 Td 84.848485 Tz (475 ) Tj 40 0 0 40 0 1374 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.35 0 Td 50 Tz (4 ) Tj 34.285714 0 0 34.285714 0 1344 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (211 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (LENGTH ) Tj 3.208333 0 Td 19.444444 Tz (: ) Tj 0.875 0 Td 76.157407 Tz (480 ) Tj 31.428571 0 0 31.428571 0 1311 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 34.285714 0 0 34.285714 0 1278 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (213 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.933333 0 Td 78.993056 Tz (ORGANISM ) Tj 4.229167 0 Td 24.305556 Tz (: ) Tj 0.875 0 Td 83.854167 Tz (Triticum ) Tj 4.608333 0 Td 83.246528 Tz (aestivum ) Tj 37.619048 0 0 37.619048 0 1207.70852 Tm 8.612658 0 Td 53.164557 Tz (< ) Tj 0.478481 0 Td 69.409283 Tz (400 ) Tj 1.435443 0 Td 53.164557 Tz (> ) Tj 0.877215 0 Td 75.316456 Tz (SEQUENCE ) Tj 3.85443 0 Td 17.721519 Tz (: ) Tj 0.770886 0 Td 53.164557 Tz (4 ) Tj 44.285714 0 0 44.285714 0 1144 Tm 7.316129 0 Td 63.978495 Tz (ttgccgagat ) Tj 4.312903 0 Td 64.354839 Tz (gcgtcgctct ) Tj 4.358065 0 Td 64.354839 Tz (ccgctcaaag ) Tj 4.335484 0 Td 64.354839 Tz (catggcaaca ) Tj 4.312903 0 Td 65.107527 Tz (gctacctgcg ) Tj 4.380645 0 Td 64.354839 Tz (ctccgtgcac ) Tj 30 0 0 30 0 1147 Tm 51.566667 0 Td 83.333333 Tz (60 ) Tj 41.428571 0 0 41.428571 0 1077 Tm 7.796552 0 Td 68.793103 Tz (gacaagagcc ) Tj 4.658621 0 Td 68.793103 Tz (agggcggcaa ) Tj 4.634483 0 Td 68.793103 Tz (cttcgtcgag ) Tj 4.634483 0 Td 68.793103 Tz (ctaagcgccg ) Tj 4.634483 0 Td 69.195402 Tz (acaacgacgg ) Tj 4.658621 0 Td 69.195402 Tz (aggcgtcatg ) Tj 30 0 0 30 0 1079 Tm 51.033333 0 Td 87.037037 Tz (120 ) Tj 41.428571 0 0 41.428571 0 1010 Tm 7.82069 0 Td 68.390805 Tz (aacccacgct ) Tj 4.610345 0 Td 69.195402 Tz (gcagattcta ) Tj 4.658621 0 Td 68.793103 Tz (cctggaggcg ) Tj 4.634483 0 Td 68.390805 Tz (tccaaggagc ) Tj 4.634483 0 Td 68.793103 Tz (acgacgggct ) Tj 4.658621 0 Td 68.793103 Tz (cgttcacgtc ) Tj 31.428571 0 0 31.428571 0 1013 Tm 48.65 0 Td 86.616162 Tz (180 ) Tj 44.285714 0 0 44.285714 0 942.847764 Tm 7.316129 0 Td 63.978495 Tz (agatgttgct ) Tj 4.358065 0 Td 65.107527 Tz (acaacaacaa ) Tj 4.358065 0 Td 68.494624 Tz (gtactgggcgccgcagcago ) Tj 8.603226 0 Td 65.107527 Tz (gcctgcttca ) Tj 4.380645 0 Td 64.354839 Tz (cggcagcgct ) Tj 30 0 0 30 0 946 Tm 50.966667 0 Td 88.888889 Tz (240 ) Tj 44.285714 0 0 44.285714 0 879 Tm 7.316129 0 Td 64.354839 Tz (cgctggacca ) Tj 4.335484 0 Td 63.978495 Tz (ttggtaccgc ) Tj 4.335484 0 Td 64.354839 Tz (aaatgagctg ) Tj 4.312903 0 Td 64.354839 Tz (gaggaggatc ) Tj 4.358065 0 Td 64.354839 Tz (tctccaagcc ) Tj 4.358065 0 Td 64.354839 Tz (atcatgcacc ) Tj 32.857143 0 0 32.857143 0 879 Tm 46.565217 0 Td 82.850242 Tz (300 ) Tj 45.714286 0 0 45.714286 0 809.832195 Tm 7.0875 0 Td 61.979167 Tz (ctgtttaagc ) Tj 4.2 0 Td 61.979167 Tz (acatccccgt ) Tj 4.2 0 Td 62.34375 Tz (ctcgggcgag ) Tj 4.178125 0 Td 62.708333 Tz (gacggctcca ) Tj 4.221875 0 Td 62.34375 Tz (cctgcaggtt ) Tj 4.221875 0 Td 62.34375 Tz (ccttcattcc ) Tj 35.714286 0 0 35.714286 0 811 Tm 42.812 0 Td 74.666667 Tz (360 ) Tj 47.142857 0 0 47.142857 0 746 Tm 6.872727 0 Td 60.454545 Tz (cagctaggaa ) Tj 4.072727 0 Td 60.454545 Tz (aatatgottg ) Tj 4.072727 0 Td 60.10101 Tz (cgtgctatcc ) Tj 4.072727 0 Td 60.454545 Tz (agttctgata ) Tj 4.072727 0 Td 60.808081 Tz (tgtccaagca ) Tj 4.093939 0 Td 60.808081 Tz (cccctacttg ) Tj 30 0 0 30 0 747 Tm 51 0 Td 88.888889 Tz (420 ) Tj 45.714286 0 0 45.714286 0 675 Tm 7.0875 0 Td 61.979167 Tz (catatagcac ) Tj 4.178125 0 Td 62.34375 Tz (gtgaagaatc ) Tj 4.221875 0 Td 61.979167 Tz (tgatcaagat ) Tj 4.2 0 Td 62.34375 Tz (aatctccttg ) Tj 4.2 0 Td 62.34375 Tz (atgcttttac ) Tj 4.221875 0 Td 62.34375 Tz (tgtccttgat ) Tj 31.428571 0 0 31.428571 0 677 Tm 48.65 0 Td 84.848485 Tz (480 ) Tj 40 0 0 40 0 566 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.375 0 Td 50 Tz (5 ) Tj 34.285714 0 0 34.285714 0 535 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (211 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (LENGTH ) Tj 3.208333 0 Td 19.444444 Tz (: ) Tj 0.875 0 Td 76.157407 Tz (405 ) Tj 31.428571 0 0 31.428571 0 500 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 37.142857 0 0 37.142857 0 463 Tm 8.723077 0 Td 53.846154 Tz (< ) Tj 0.484615 0 Td 68.803419 Tz (213 ) Tj 1.453846 0 Td 53.846154 Tz (> ) Tj 0.861538 0 Td 74.599359 Tz (ORGANISM ) Tj 3.903846 0 Td 22.435897 Tz (: ) Tj 0.807692 0 Td 77.403846 Tz (Triticum ) Tj 4.253846 0 Td 76.842949 Tz (aestivum ) Tj 40.47619 0 0 40.47619 0 389.654709 Tm 8.004706 0 Td 49.411765 Tz (< ) Tj 0.444706 0 Td 64.509804 Tz (400 ) Tj 1.334118 0 Td 49.411765 Tz (> ) Tj 0.815294 0 Td 70 Tz (SEQUENCE ) Tj 3.582353 0 Td 16.470588 Tz (: ) Tj 0.741176 0 Td 49.411765 Tz (5 ) Tj 41.428571 0 0 41.428571 0 323 Tm 7.82069 0 Td 68.390805 Tz (atgcagttgc ) Tj 4.634483 0 Td 68.390805 Tz (ctagttatct ) Tj 4.634483 0 Td 68.793103 Tz (tgctttcaaa ) Tj 4.610345 0 Td 69.195402 Tz (ggcgacaatg ) Tj 4.634483 0 Td 69.195402 Tz (ggaggttcct ) Tj 4.682759 0 Td 69.195402 Tz (tggtgcgaag ) Tj 32.857143 0 0 32.857143 0 324 Tm 47.082609 0 Td 81.15942 Tz (60 ) Tj 41.428571 0 0 41.428571 0 253 Tm 7.82069 0 Td 68.793103 Tz (atcgtcgagg ) Tj 4.610345 0 Td 69.195402 Tz (gttatagata ) Tj 4.658621 0 Td 68.390805 Tz (tcttgaatac ) Tj 4.634483 0 Td 68.793103 Tz (tccaaagatg ) Tj 4.634483 0 Td 69.195402 Tz (atattggaga ) Tj 4.658621 0 Td 69.195402 Tz (tetaagtgtg ) Tj 31.428571 0 0 31.428571 0 254 Tm 48.713636 0 Td 83.080808 Tz (120 ) Tj ET Q endstream endobj 205 0 obj << /Length 1 >> stream q endstream endobj 206 0 obj << /Length 17960 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 54.285714 0 0 54.285714 0 2969 Tm 13.723684 0 Td 73.684211 Tz (37 ) Tj 55.714286 0 0 55.714286 0 2971 Tm 30.853846 0 Td 71.794872 Tz (38 ) Tj 46.428571 0 0 46.428571 0 2909.056604 Tm 24.36 0 Td 43.076923 Tz (- ) Tj 0.430769 0 Td 79.77208 Tz (continued ) Tj 41.428571 0 0 41.428571 0 2837.998054 Tm 7.82069 0 Td 68.793103 Tz (ttgcacacaa ) Tj 4.634483 0 Td 68.793103 Tz (ttttcaccaa ) Tj 4.634483 0 Td 68.793103 Tz (taaagatgga ) Tj 4.610345 0 Td 69.195402 Tz (gttgtccgta ) Tj 4.658621 0 Td 69.195402 Tz (taaaatccaa ) Tj 4.658621 0 Td 68.793103 Tz (ctatttcgac ) Tj 28.571429 0 0 28.571429 0 2843 Tm 53.585 0 Td 91.388889 Tz (180 ) Tj 45.714286 0 0 45.714286 0 2773.831055 Tm 7.0875 0 Td 62.34375 Tz (atgttttgga ) Tj 4.178125 0 Td 62.34375 Tz (ggcgaagccc ) Tj 4.221875 0 Td 61.979167 Tz (aaattggatc ) Tj 4.2 0 Td 61.979167 Tz (tgggctgatt ) Tj 4.2 0 Td 62.34375 Tz (caactgacac ) Tj 4.221875 0 Td 62.34375 Tz (cacccacaac ) Tj 30 0 0 30 0 2778 Tm 50.966667 0 Td 88.888889 Tz (240 ) Tj 45.714286 0 0 45.714286 0 2705.835603 Tm 7.0875 0 Td 62.34375 Tz (aaccgtgata ) Tj 4.2 0 Td 62.34375 Tz (cattattcaa ) Tj 4.178125 0 Td 62.34375 Tz (ggtgaccact ) Tj 4.2 0 Td 62.34375 Tz (gggcccgact ) Tj 4.221875 0 Td 62.34375 Tz (tcattgctct ) Tj 4.2 0 Td 63.072917 Tz (gegaaacttg ) Tj 32.857143 0 0 32.857143 0 2709 Tm 46.565217 0 Td 81.15942 Tz (300 ) Tj 41.428571 0 0 41.428571 0 2642 Tm 7.796552 0 Td 69.195402 Tz (ggcaacaaca ) Tj 4.658621 0 Td 68.793103 Tz (atttctgcaa ) Tj 4.634483 0 Td 68.390805 Tz (aaggttaacc ) Tj 4.634483 0 Td 68.793103 Tz (acagaaggga ) Tj 4.634483 0 Td 69.195402 Tz (agtatgattg ) Tj 4.658621 0 Td 68.793103 Tz (cctcaatgct ) Tj 28.571429 0 0 28.571429 0 2645 Tm 53.55 0 Td 93.333333 Tz (360 ) Tj 42.857143 0 0 42.857143 0 2574 Tm 7.536667 0 Td 66.5 Tz (gctgttggtt ) Tj 4.503333 0 Td 66.111111 Tz (ccatcacagc ) Tj 4.48 0 Td 66.5 Tz (tgaagtaaaa ) Tj 4.48 0 Td 66.5 Tz (atgcggtgca ) Tj 4.48 0 Td 65.333333 Tz (ttgaa ) Tj 30 0 0 30 0 2578 Tm 50.966667 0 Td 88.888889 Tz (405 ) Tj 38.571429 0 0 38.571429 0 2472 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.425926 0 Td 47.530864 Tz (6 ) Tj 31.428571 0 0 31.428571 0 2442 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 83.080808 Tz (288 ) Tj 32.857143 0 0 32.857143 0 2408 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 37.142857 0 0 37.142857 0 2376 Tm 8.723077 0 Td 53.846154 Tz (< ) Tj 0.484615 0 Td 68.803419 Tz (213 ) Tj 1.453846 0 Td 53.846154 Tz (> ) Tj 0.861538 0 Td 74.599359 Tz (ORGANISM ) Tj 3.903846 0 Td 22.435897 Tz (: ) Tj 0.807692 0 Td 77.403846 Tz (Triticum ) Tj 4.253846 0 Td 76.842949 Tz (aestivum ) Tj 37.619048 0 0 37.619048 0 2305.642857 Tm 8.612658 0 Td 44.303797 Tz (< ) Tj 0.531646 0 Td 62.025316 Tz (400 ) Tj 1.462025 0 Td 39.873418 Tz (> ) Tj 0.797468 0 Td 75.316456 Tz (SEQUENCE ) Tj 3.881013 0 Td 8.860759 Tz (: ) Tj 0.770886 0 Td 48.734177 Tz (6 ) Tj 42.857143 0 0 42.857143 0 2241.5 Tm 7.536667 0 Td 66.888889 Tz (gatagtcaaa ) Tj 4.503333 0 Td 66.5 Tz (ttgttgaaaa ) Tj 4.48 0 Td 66.111111 Tz (catgaccacc ) Tj 4.48 0 Td 66.5 Tz (acaacaaaca ) Tj 41.428571 0 0 41.428571 0 2241.514535 Tm 26.358621 0 Td 68.793103 Tz (aaaccaaaat ) Tj 4.634483 0 Td 69.597701 Tz (gatcttcaca ) Tj 28.571429 0 0 28.571429 0 2246 Tm 54.145 0 Td 87.5 Tz (60 ) Tj 47.142857 0 0 47.142857 0 2173.832195 Tm 6.872727 0 Td 60.454545 Tz (tacacaaata ) Tj 4.072727 0 Td 60.454545 Tz (ccgtccagag ) Tj 4.072727 0 Td 60.10101 Tz (tacctggagt ) Tj 4.072727 0 Td 60.10101 Tz (tctactgttt ) Tj 4.072727 0 Td 60.454545 Tz (cattgaagat ) Tj 4.093939 0 Td 60.808081 Tz (tggcgtcaag ) Tj 32.857143 0 0 32.857143 0 2176 Tm 46.595652 0 Td 79.468599 Tz (120 ) Tj 44.285714 0 0 44.285714 0 2107.834469 Tm 7.316129 0 Td 64.354839 Tz (accaaattta ) Tj 4.335484 0 Td 63.978495 Tz (aatccgggat ) Tj 4.335484 0 Td 64.354839 Tz (tccatttgta ) Tj 4.312903 0 Td 64.731183 Tz (gttgacggcg ) Tj 4.358065 0 Td 64.354839 Tz (aagttgaggt ) Tj 4.358065 0 Td 64.731183 Tz (cagcactgag ) Tj 30 0 0 30 0 2113 Tm 51 0 Td 87.037037 Tz (180 ) Tj 44.285714 0 0 44.285714 0 2043 Tm 7.316129 0 Td 63.978495 Tz (tttagtggat ) Tj 4.335484 0 Td 64.354839 Tz (catatacctg ) Tj 4.312903 0 Td 64.354839 Tz (ggggggagcc ) Tj 4.358065 0 Td 64.354839 Tz (aaatctgaca ) Tj 4.335484 0 Td 64.354839 Tz (caaaagtagt ) Tj 4.358065 0 Td 64.731183 Tz (aagcaaacaa ) Tj 31.428571 0 0 31.428571 0 2044 Tm 48.65 0 Td 84.848485 Tz (240 ) Tj 42.857143 0 0 42.857143 0 1975 Tm 7.56 0 Td 66.5 Tz (attgatgttg ) Tj 4.48 0 Td 66.111111 Tz (aagttcctcc ) Tj 4.48 0 Td 66.5 Tz (aatgaagaaa ) Tj 4.456667 0 Td 66.888889 Tz (gtgacagtaa ) Tj 4.503333 0 Td 66.111111 Tz (aagcgatt ) Tj 28.571429 0 0 28.571429 0 1978 Tm 53.55 0 Td 93.333333 Tz (288 ) Tj 37.142857 0 0 37.142857 0 1874 Tm 8.723077 0 Td 53.846154 Tz (< ) Tj 0.484615 0 Td 70.299145 Tz (210 ) Tj 1.453846 0 Td 53.846154 Tz (> ) Tj 0.888462 0 Td 74.786325 Tz (SEQ ) Tj 1.911538 0 Td 67.307692 Tz (ID ) Tj 1.319231 0 Td 76.282051 Tz (NO ) Tj 1.480769 0 Td 53.846154 Tz (7 ) Tj 34.285714 0 0 34.285714 0 1843 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (211 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (LENGTH ) Tj 3.208333 0 Td 19.444444 Tz (: ) Tj 0.904167 0 Td 74.537037 Tz (160 ) Tj 31.428571 0 0 31.428571 0 1811 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 86.616162 Tz (PRT ) Tj 34.285714 0 0 34.285714 0 1777 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (213 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.933333 0 Td 78.993056 Tz (ORGANISM ) Tj 4.229167 0 Td 24.305556 Tz (: ) Tj 0.875 0 Td 83.854167 Tz (Triticum ) Tj 4.608333 0 Td 83.246528 Tz (aestivum ) Tj 41.142857 0 0 41.142857 0 1705.78673 Tm 7.875 0 Td 48.611111 Tz (< ) Tj 0.4375 0 Td 63.464506 Tz (400 ) Tj 1.3125 0 Td 48.611111 Tz (> ) Tj 0.802083 0 Td 68.865741 Tz (SEQUENCE ) Tj 3.524306 0 Td 16.203704 Tz (: ) Tj 25.714286 0 0 25.714286 0 1714 Tm 23.45 0 Td 77.777778 Tz (7 ) Tj 44.285714 0 0 44.285714 0 1640.617315 Tm 7.316129 0 Td 62.724014 Tz (Leu ) Tj 1.580645 0 Td 61.469534 Tz (Pro ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 60.215054 Tz (Cys ) Tj 1.512903 0 Td 62.724014 Tz (Val ) Tj 1.580645 0 Td 63.978495 Tz (Ala ) Tj 1.625806 0 Td 62.724014 Tz (Leu ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.558065 0 Td 60.215054 Tz (His ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 65.232975 Tz (Asn ) Tj 1.625806 0 Td 62.724014 Tz (Ser ) Tj 1.603226 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 62.724014 Tz (Leu ) Tj 27.142857 0 0 27.142857 0 1612 Tm 11.936842 0 Td 73.684211 Tz (1 ) Tj 28.571429 0 0 28.571429 0 1613 Tm 21.105 0 Td 70 Tz (5 ) Tj 28.571429 0 0 28.571429 0 1612 Tm 33.355 0 Td 84.583333 Tz (10 ) Tj 28.571429 0 0 28.571429 0 1611 Tm 45.605 0 Td 84.583333 Tz (15 ) Tj 45.714286 0 0 45.714286 0 1539.202247 Tm 7.04375 0 Td 61.979167 Tz (Arg ) Tj 1.575 0 Td 59.548611 Tz (Ser ) Tj 1.4875 0 Td 60.763889 Tz (Val ) Tj 1.553125 0 Td 59.548611 Tz (His ) Tj 1.4875 0 Td 61.979167 Tz (Asp ) Tj 1.575 0 Td 58.333333 Tz (Lys ) Tj 1.53125 0 Td 59.548611 Tz (Ser ) Tj 1.509375 0 Td 61.979167 Tz (Gin ) Tj 1.53125 0 Td 61.979167 Tz (Gly ) Tj 1.53125 0 Td 61.979167 Tz (Gly ) Tj 1.509375 0 Td 61.979167 Tz (Asn ) Tj 1.553125 0 Td 59.548611 Tz (Phe ) Tj 1.4875 0 Td 60.763889 Tz (Val ) Tj 1.553125 0 Td 63.194444 Tz (Glu ) Tj 1.575 0 Td 60.763889 Tz (Leu ) Tj 1.53125 0 Td 59.548611 Tz (Ser ) Tj 31.428571 0 0 31.428571 0 1510 Tm 16.990909 0 Td 79.545455 Tz (20 ) Tj 31.428571 0 0 31.428571 0 1511 Tm 28.095455 0 Td 79.545455 Tz (25 ) Tj 31.428571 0 0 31.428571 0 1511 Tm 39.2 0 Td 79.545455 Tz (30 ) Tj 42.857143 0 0 42.857143 0 1439.996273 Tm 7.513333 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 63.518519 Tz (Met ) Tj 1.61 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Pro ) Tj 1.586667 0 Td 64.814815 Tz (Arg ) Tj 1.656667 0 Td 62.222222 Tz (Cys ) Tj 1.586667 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 64.814815 Tz (Phe ) Tj 1.656667 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 30 0 0 30 0 1412 Tm 15.433333 0 Td 83.333333 Tz (35 ) Tj 28.571429 0 0 28.571429 0 1413 Tm 28.42 0 Td 87.5 Tz (40 ) Tj 31.428571 0 0 31.428571 0 1412 Tm 36.940909 0 Td 79.545455 Tz (45 ) Tj 47.142857 0 0 47.142857 0 1339.051508 Tm 6.851515 0 Td 60.10101 Tz (Glu ) Tj 1.463636 0 Td 60.10101 Tz (Ala ) Tj 1.527273 0 Td 57.744108 Tz (Ser ) Tj 1.484848 0 Td 56.565657 Tz (Lys ) Tj 1.442424 0 Td 60.10101 Tz (Glu ) Tj 1.484848 0 Td 57.744108 Tz (His ) Tj 1.463636 0 Td 60.10101 Tz (Asp ) Tj 1.506061 0 Td 60.10101 Tz (Gly ) Tj 1.506061 0 Td 58.922559 Tz (Leu ) Tj 1.442424 0 Td 58.922559 Tz (Val ) Tj 1.506061 0 Td 56.565657 Tz (His ) Tj 1.442424 0 Td 58.922559 Tz (Val ) Tj 1.484848 0 Td 60.10101 Tz (Arg ) Tj 1.527273 0 Td 57.744108 Tz (Cys ) Tj 1.506061 0 Td 56.565657 Tz (Cys ) Tj 1.484848 0 Td 57.744108 Tz (Tyr ) Tj 31.428571 0 0 31.428571 0 1311 Tm 34.745455 0 Td 79.545455 Tz (60 ) Tj 27.142857 0 0 27.142857 0 1314 Tm 14.515789 0 Td 89.035088 Tz (50 ) Tj 27.142857 0 0 27.142857 0 1313 Tm 27.373684 0 Td 92.105263 Tz (55 ) Tj 42.857143 0 0 42.857143 0 1239.860523 Tm 7.513333 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.61 0 Td 63.518519 Tz (Trp ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.68 0 Td 63.518519 Tz (Pro ) Tj 1.61 0 Td 66.111111 Tz (Gin ) Tj 1.633333 0 Td 66.111111 Tz (Gin ) Tj 1.61 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 63.518519 Tz (Leu ) Tj 1.61 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.633333 0 Td 67.407407 Tz (Gly ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 28.571429 0 0 28.571429 0 1214 Tm 11.34 0 Td 87.5 Tz (65 ) Tj 28.571429 0 0 28.571429 0 1214 Tm 23.555 0 Td 87.5 Tz (70 ) Tj 28.571429 0 0 28.571429 0 1214 Tm 35.77 0 Td 87.5 Tz (75 ) Tj 28.571429 0 0 28.571429 0 1213 Tm 48.055 0 Td 84.583333 Tz (80 ) Tj 44.285714 0 0 44.285714 0 1140.184769 Tm 7.270968 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 61.469534 Tz (Trp ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.512903 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 61.469534 Tz (Thr ) Tj 1.535484 0 Td 63.978495 Tz (Ala ) Tj 1.580645 0 Td 65.232975 Tz (Asn ) Tj 1.603226 0 Td 63.978495 Tz (Glu ) Tj 1.603226 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 62.724014 Tz (Glu ) Tj 1.558065 0 Td 63.978495 Tz (Glu ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.625806 0 Td 63.978495 Tz (Leu ) Tj 1.603226 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 28.571429 0 0 28.571429 0 1114 Tm 21.105 0 Td 87.5 Tz (85 ) Tj 28.571429 0 0 28.571429 0 1114 Tm 33.355 0 Td 84.583333 Tz (90 ) Tj 31.428571 0 0 31.428571 0 1112 Tm 41.459091 0 Td 76.893939 Tz (95 ) Tj 42.857143 0 0 42.857143 0 1039.888748 Tm 7.56 0 Td 63.518519 Tz (Pro ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.61 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Pro ) Tj 1.586667 0 Td 63.518519 Tz (Val ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 67.407407 Tz (Glu ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 31.428571 0 0 31.428571 0 1011 Tm 17.022727 0 Td 81.313131 Tz (100 ) Tj 32.857143 0 0 32.857143 0 1012 Tm 26.873913 0 Td 79.468599 Tz (105 ) Tj 30 0 0 30 0 1013 Tm 41.033333 0 Td 90.740741 Tz (110 ) Tj 42.857143 0 0 42.857143 0 940.227273 Tm 7.56 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.586667 0 Td 66.111111 Tz (Arg ) Tj 1.656667 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Gin ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 64.814815 Tz (Gly ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 67.407407 Tz (Ala ) Tj 1.703333 0 Td 62.222222 Tz (Cys ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 32.857143 0 0 32.857143 0 911 Tm 14.121739 0 Td 79.468599 Tz (115 ) Tj 30 0 0 30 0 913 Tm 27.1 0 Td 87.037037 Tz (120 ) Tj 32.857143 0 0 32.857143 0 912 Tm 35.395652 0 Td 79.468599 Tz (125 ) Tj 40 0 0 40 0 841.503797 Tm 8.1 0 Td 69.444444 Tz (Leu ) Tj 1.75 0 Td 68.055556 Tz (Ser ) Tj 1.75 0 Td 68.055556 Tz (Ser ) Tj 1.75 0 Td 68.055556 Tz (Ser ) Tj 1.675 0 Td 70.833333 Tz (Asp ) Tj 1.775 0 Td 68.055556 Tz (Met ) Tj 1.775 0 Td 68.055556 Tz (Ser ) Tj 1.75 0 Td 66.666667 Tz (Lys ) Tj 1.725 0 Td 68.055556 Tz (His ) Tj 1.775 0 Td 68.055556 Tz (Pro ) Tj 1.75 0 Td 66.666667 Tz (Tyr ) Tj 1.725 0 Td 69.444444 Tz (Leu ) Tj 1.725 0 Td 68.055556 Tz (His ) Tj 1.8 0 Td 68.055556 Tz (Ile ) Tj 1.7 0 Td 70.833333 Tz (Ala ) Tj 1.75 0 Td 70.833333 Tz (Arg ) Tj 32.857143 0 0 32.857143 0 811 Tm 12.021739 0 Td 79.468599 Tz (130 ) Tj 32.857143 0 0 32.857143 0 812 Tm 22.643478 0 Td 79.468599 Tz (135 ) Tj 32.857143 0 0 32.857143 0 812 Tm 33.265217 0 Td 79.468599 Tz (140 ) Tj 41.428571 0 0 41.428571 0 741.516729 Tm 7.796552 0 Td 68.390805 Tz (Glu ) Tj 1.689655 0 Td 68.390805 Tz (Glu ) Tj 1.713793 0 Td 65.708812 Tz (Ser ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.689655 0 Td 68.390805 Tz (Gin ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 1.689655 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.689655 0 Td 67.049808 Tz (Ala ) Tj 1.713793 0 Td 65.708812 Tz (Phe ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 68.390805 Tz (Val ) Tj 1.762069 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 31.428571 0 0 31.428571 0 714 Tm 10.309091 0 Td 83.080808 Tz (145 ) Tj 34.285714 0 0 34.285714 0 712 Tm 19.629167 0 Td 76.157407 Tz (150 ) Tj 32.857143 0 0 32.857143 0 712 Tm 31.134783 0 Td 79.468599 Tz (155 ) Tj 31.428571 0 0 31.428571 0 713 Tm 43.718182 0 Td 81.313131 Tz (160 ) Tj 38.571429 0 0 38.571429 0 603 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.425926 0 Td 51.851852 Tz (8 ) Tj 31.428571 0 0 31.428571 0 570 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.986364 0 Td 81.313131 Tz (135 ) Tj 34.285714 0 0 34.285714 0 535 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (212 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 80.208333 Tz (TYPE ) Tj 2.1875 0 Td 19.444444 Tz (: ) Tj 0.875 0 Td 79.398148 Tz (PRT ) Tj 34.285714 0 0 34.285714 0 500 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (213 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.933333 0 Td 79.600694 Tz (ORGANISM ) Tj 4.229167 0 Td 24.305556 Tz (: ) Tj 0.875 0 Td 83.854167 Tz (Triticum ) Tj 4.608333 0 Td 83.246528 Tz (aestivum ) Tj 39.047619 0 0 39.047619 0 424.70852 Tm 8.297561 0 Td 51.219512 Tz (< ) Tj 0.460976 0 Td 66.869919 Tz (400 ) Tj 1.382927 0 Td 51.219512 Tz (> ) Tj 0.845122 0 Td 72.560976 Tz (SEQUENCE ) Tj 3.713415 0 Td 17.073171 Tz (: ) Tj 0.768293 0 Td 51.219512 Tz (8 ) Tj 45.714286 0 0 45.714286 0 353.63375 Tm 7.065625 0 Td 59.548611 Tz (Met ) Tj 1.53125 0 Td 61.979167 Tz (Gin ) Tj 1.553125 0 Td 60.763889 Tz (Leu ) Tj 1.53125 0 Td 59.548611 Tz (Pro ) Tj 1.509375 0 Td 59.548611 Tz (Ser ) Tj 1.53125 0 Td 59.548611 Tz (Tyr ) Tj 1.53125 0 Td 60.763889 Tz (Leu ) Tj 1.4875 0 Td 61.979167 Tz (Ala ) Tj 1.575 0 Td 59.548611 Tz (Phe ) Tj 1.53125 0 Td 58.333333 Tz (Lys ) Tj 1.509375 0 Td 60.763889 Tz (Gly ) Tj 1.4875 0 Td 61.979167 Tz (Asp ) Tj 1.53125 0 Td 63.194444 Tz (Asn ) Tj 1.553125 0 Td 63.194444 Tz (Gly ) Tj 1.53125 0 Td 61.979167 Tz (Arg ) Tj 1.575 0 Td 59.548611 Tz (Phe ) Tj 27.142857 0 0 27.142857 0 325 Tm 11.973684 0 Td 73.684211 Tz (1 ) Tj 31.428571 0 0 31.428571 0 324 Tm 19.218182 0 Td 63.636364 Tz (5 ) Tj 32.857143 0 0 32.857143 0 325 Tm 28.973913 0 Td 78.623188 Tz (10 ) Tj 31.428571 0 0 31.428571 0 324 Tm 41.459091 0 Td 82.19697 Tz (15 ) Tj 42.857143 0 0 42.857143 0 248.984925 Tm 7.56 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 66.111111 Tz (Ala ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 62.222222 Tz (Ile ) Tj 1.563333 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 62.222222 Tz (Tyr ) Tj 1.61 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 64.814815 Tz (Tyr ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 28.571429 0 0 28.571429 0 220 Tm 18.655 0 Td 87.5 Tz (20 ) Tj 27.142857 0 0 27.142857 0 221 Tm 32.494737 0 Td 92.105263 Tz (25 ) Tj 30 0 0 30 0 220 Tm 41.033333 0 Td 83.333333 Tz (30 ) Tj ET Q endstream endobj 207 0 obj << /Length 1 >> stream q endstream endobj 208 0 obj << /Length 17306 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 52.857143 0 0 52.857143 0 2971 Tm 14.094595 0 Td 75.675676 Tz (39 ) Tj 58.571429 0 0 58.571429 0 2968 Tm 29.34878 0 Td 69.715447 Tz (40 ) Tj 47.857143 0 0 47.857143 0 2907.056604 Tm 23.632836 0 Td 41.791045 Tz (- ) Tj 0.41791 0 Td 77.390824 Tz (continued ) Tj 45.714286 0 0 45.714286 0 2804.218868 Tm 7.04375 0 Td 61.979167 Tz (Asp ) Tj 1.53125 0 Td 61.979167 Tz (Asp ) Tj 1.596875 0 Td 58.333333 Tz (Ile ) Tj 1.4875 0 Td 61.979167 Tz (Gly ) Tj 1.4875 0 Td 61.979167 Tz (Asp ) Tj 1.575 0 Td 60.763889 Tz (Leu ) Tj 1.53125 0 Td 59.548611 Tz (Ser ) Tj 1.4875 0 Td 60.763889 Tz (Val ) Tj 1.575 0 Td 60.763889 Tz (Leu ) Tj 1.509375 0 Td 59.548611 Tz (His ) Tj 1.553125 0 Td 58.333333 Tz (Thr ) Tj 1.53125 0 Td 58.333333 Tz (Ile ) Tj 1.509375 0 Td 59.548611 Tz (Phe ) Tj 1.53125 0 Td 60.763889 Tz (Thr ) Tj 1.509375 0 Td 63.194444 Tz (Asn ) Tj 1.575 0 Td 58.333333 Tz (Lys ) Tj 28.571429 0 0 28.571429 0 2778 Tm 16.205 0 Td 87.5 Tz (35 ) Tj 28.571429 0 0 28.571429 0 2778 Tm 28.42 0 Td 87.5 Tz (40 ) Tj 30 0 0 30 0 2778 Tm 38.7 0 Td 83.333333 Tz (45 ) Tj 41.428571 0 0 41.428571 0 2706.018821 Tm 7.772414 0 Td 68.390805 Tz (Asp ) Tj 1.713793 0 Td 68.390805 Tz (Gly ) Tj 1.665517 0 Td 67.049808 Tz (Val ) Tj 1.689655 0 Td 67.049808 Tz (Val ) Tj 1.665517 0 Td 68.390805 Tz (Arg ) Tj 1.762069 0 Td 64.367816 Tz (Ile ) Tj 1.665517 0 Td 64.367816 Tz (Lys ) Tj 1.689655 0 Td 65.708812 Tz (Ser ) Tj 1.641379 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 65.708812 Tz (Tyr ) Tj 1.689655 0 Td 64.367816 Tz (Phe ) Tj 1.617241 0 Td 68.390805 Tz (Asp ) Tj 1.713793 0 Td 65.708812 Tz (Met ) Tj 1.713793 0 Td 67.049808 Tz (Phe ) Tj 1.713793 0 Td 65.708812 Tz (Trp ) Tj 1.641379 0 Td 68.390805 Tz (Arg ) Tj 27.142857 0 0 27.142857 0 2679 Tm 14.515789 0 Td 89.035088 Tz (50 ) Tj 34.285714 0 0 34.285714 0 2675 Tm 21.670833 0 Td 77.777778 Tz (55 ) Tj 34.285714 0 0 34.285714 0 2676 Tm 31.85 0 Td 75.347222 Tz (60 ) Tj 44.285714 0 0 44.285714 0 2604.204517 Tm 7.270968 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 61.469534 Tz (Pro ) Tj 1.535484 0 Td 65.232975 Tz (Asn ) Tj 1.603226 0 Td 61.469534 Tz (Trp ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.558065 0 Td 61.469534 Tz (Trp ) Tj 1.535484 0 Td 63.978495 Tz (Ala ) Tj 1.580645 0 Td 63.978495 Tz (Asp ) Tj 1.625806 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 60.215054 Tz (Thr ) Tj 1.512903 0 Td 63.978495 Tz (Asp ) Tj 1.625806 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 62.724014 Tz (Thr ) Tj 1.580645 0 Td 61.469534 Tz (His ) Tj 1.558065 0 Td 65.232975 Tz (Asn ) Tj 28.571429 0 0 28.571429 0 2578 Tm 11.34 0 Td 87.5 Tz (65 ) Tj 27.142857 0 0 27.142857 0 2579 Tm 24.794737 0 Td 92.105263 Tz (70 ) Tj 28.571429 0 0 28.571429 0 2578 Tm 35.77 0 Td 87.5 Tz (75 ) Tj 28.571429 0 0 28.571429 0 2578 Tm 48.055 0 Td 84.583333 Tz (80 ) Tj 44.285714 0 0 44.285714 0 2505.204517 Tm 7.270968 0 Td 65.232975 Tz (Asn ) Tj 1.580645 0 Td 63.978495 Tz (Arg ) Tj 1.580645 0 Td 63.978495 Tz (Asp ) Tj 1.625806 0 Td 61.469534 Tz (Thr ) Tj 1.558065 0 Td 62.724014 Tz (Leu ) Tj 1.580645 0 Td 61.469534 Tz (Phe ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.558065 0 Td 62.724014 Tz (Gly ) Tj 1.580645 0 Td 61.469534 Tz (Pro ) Tj 1.535484 0 Td 63.978495 Tz (Asp ) Tj 1.625806 0 Td 62.724014 Tz (Phe ) Tj 1.625806 0 Td 60.215054 Tz (Ile ) Tj 1.512903 0 Td 63.978495 Tz (Ala ) Tj 32.857143 0 0 32.857143 0 2476 Tm 18.321739 0 Td 81.15942 Tz (85 ) Tj 34.285714 0 0 34.285714 0 2476 Tm 27.795833 0 Td 75.347222 Tz (90 ) Tj 32.857143 0 0 32.857143 0 2475 Tm 39.656522 0 Td 78.623188 Tz (95 ) Tj 42.857143 0 0 42.857143 0 2404.848447 Tm 7.56 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 66.111111 Tz (Arg ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 60.925926 Tz (Lys ) Tj 1.563333 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 64.814815 Tz (Thr ) Tj 1.656667 0 Td 63.518519 Tz (Thr ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 31.428571 0 0 31.428571 0 2378 Tm 16.990909 0 Td 81.313131 Tz (100 ) Tj 31.428571 0 0 31.428571 0 2377 Tm 28.095455 0 Td 83.080808 Tz (105 ) Tj 31.428571 0 0 31.428571 0 2378 Tm 39.2 0 Td 84.848485 Tz (110 ) Tj 48.571429 0 0 48.571429 0 2305.59875 Tm 6.65 0 Td 58.333333 Tz (Gly ) Tj 1.461765 0 Td 54.901961 Tz (Lys ) Tj 1.441176 0 Td 56.045752 Tz (Tyr ) Tj 1.4 0 Td 58.333333 Tz (Asp ) Tj 1.461765 0 Td 54.901961 Tz (Cys ) Tj 1.441176 0 Td 57.189542 Tz (Leu ) Tj 1.4 0 Td 59.477124 Tz (Asn ) Tj 1.441176 0 Td 58.333333 Tz (Ala ) Tj 1.441176 0 Td 58.333333 Tz (Ala ) Tj 1.441176 0 Td 57.189542 Tz (Val ) Tj 1.461765 0 Td 57.189542 Tz (Gly ) Tj 1.441176 0 Td 56.045752 Tz (Ser ) Tj 1.461765 0 Td 54.901961 Tz (Ile ) Tj 1.420588 0 Td 57.189542 Tz (Thr ) Tj 1.420588 0 Td 58.333333 Tz (Ala ) Tj 1.461765 0 Td 58.333333 Tz (Glu ) Tj 28.571429 0 0 28.571429 0 2279 Tm 16.24 0 Td 91.388889 Tz (115 ) Tj 28.571429 0 0 28.571429 0 2278 Tm 28.455 0 Td 91.388889 Tz (120 ) Tj 31.428571 0 0 31.428571 0 2278 Tm 37.004545 0 Td 83.080808 Tz (125 ) Tj 45.714286 0 0 45.714286 0 2205.982609 Tm 7.04375 0 Td 60.763889 Tz (Val ) Tj 1.575 0 Td 58.333333 Tz (Lys ) Tj 1.509375 0 Td 59.548611 Tz (Met ) Tj 1.509375 0 Td 61.979167 Tz (Arg ) Tj 1.553125 0 Td 58.333333 Tz (Cys ) Tj 1.553125 0 Td 58.333333 Tz (Ile ) Tj 1.4875 0 Td 61.979167 Tz (Glu ) Tj 31.428571 0 0 31.428571 0 2177 Tm 12.568182 0 Td 83.080808 Tz (130 ) Tj 31.428571 0 0 31.428571 0 2177 Tm 23.672727 0 Td 83.080808 Tz (135 ) Tj 38.571429 0 0 38.571429 0 2073 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.425926 0 Td 51.851852 Tz (9 ) Tj 31.428571 0 0 31.428571 0 2043 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.986364 0 Td 76.893939 Tz (78 ) Tj 32.857143 0 0 32.857143 0 2010 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.913043 0 Td 82.850242 Tz (PRT ) Tj 34.285714 0 0 34.285714 0 1976 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (213 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.933333 0 Td 79.600694 Tz (ORGANISM ) Tj 4.229167 0 Td 24.305556 Tz (: ) Tj 0.875 0 Td 83.854167 Tz (Triticum ) Tj 4.608333 0 Td 83.246528 Tz (aestivum ) Tj 40.47619 0 0 40.47619 0 1906.63964 Tm 8.004706 0 Td 49.411765 Tz (< ) Tj 0.444706 0 Td 64.509804 Tz (400 ) Tj 1.334118 0 Td 49.411765 Tz (> ) Tj 0.815294 0 Td 70 Tz (SEQUENCE ) Tj 3.607059 0 Td 12.352941 Tz (: ) Tj 0.716471 0 Td 49.411765 Tz (9 ) Tj 42.857143 0 0 42.857143 0 1837.735777 Tm 7.56 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.563333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Gin ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 62.222222 Tz (Trp ) Tj 1.61 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 64.814815 Tz (Thr ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 27.142857 0 0 27.142857 0 1812 Tm 11.973684 0 Td 73.684211 Tz (1 ) Tj 27.142857 0 0 27.142857 0 1812 Tm 22.252632 0 Td 73.684211 Tz (5 ) Tj 30 0 0 30 0 1811 Tm 31.766667 0 Td 80.555556 Tz (10 ) Tj 28.571429 0 0 28.571429 0 1813 Tm 45.605 0 Td 84.583333 Tz (15 ) Tj 44.285714 0 0 44.285714 0 1740.621656 Tm 7.316129 0 Td 62.724014 Tz (Leu ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.535484 0 Td 63.978495 Tz (Gly ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 60.215054 Tz (Lys ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.580645 0 Td 61.469534 Tz (Phe ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.580645 0 Td 60.215054 Tz (Ser ) Tj 1.535484 0 Td 63.978495 Tz (Gly ) Tj 1.625806 0 Td 60.215054 Tz (Ile ) Tj 1.558065 0 Td 62.724014 Tz (Pro ) Tj 1.603226 0 Td 61.469534 Tz (Phe ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 30 0 0 30 0 1712 Tm 17.766667 0 Td 83.333333 Tz (20 ) Tj 30 0 0 30 0 1713 Tm 29.4 0 Td 83.333333 Tz (25 ) Tj 30 0 0 30 0 1713 Tm 41.033333 0 Td 83.333333 Tz (30 ) Tj 42.857143 0 0 42.857143 0 1638.516896 Tm 7.513333 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 66.111111 Tz (Glu ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 62.222222 Tz (Phe ) Tj 1.61 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 64.814815 Tz (Ser ) Tj 1.656667 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 28.571429 0 0 28.571429 0 1612 Tm 16.205 0 Td 87.5 Tz (35 ) Tj 28.571429 0 0 28.571429 0 1612 Tm 28.42 0 Td 87.5 Tz (40 ) Tj 30 0 0 30 0 1611 Tm 38.7 0 Td 83.333333 Tz (45 ) Tj 47.142857 0 0 47.142857 0 1539.5 Tm 6.872727 0 Td 57.744108 Tz (Trp ) Tj 1.463636 0 Td 60.10101 Tz (Gly ) Tj 1.484848 0 Td 60.10101 Tz (Gly ) Tj 1.463636 0 Td 60.10101 Tz (Ala ) Tj 1.506061 0 Td 56.565657 Tz (Lys ) Tj 1.484848 0 Td 57.744108 Tz (Ser ) Tj 1.442424 0 Td 60.10101 Tz (Asp ) Tj 1.527273 0 Td 57.744108 Tz (Thr ) Tj 1.484848 0 Td 56.565657 Tz (Lys ) Tj 1.442424 0 Td 58.922559 Tz (Val ) Tj 1.484848 0 Td 57.744108 Tz (Val ) Tj 1.506061 0 Td 57.744108 Tz (Ser ) Tj 1.484848 0 Td 56.565657 Tz (Lys ) Tj 1.463636 0 Td 61.279461 Tz (Gin ) Tj 1.548485 0 Td 56.565657 Tz (Ile ) Tj 1.421212 0 Td 60.10101 Tz (Asp ) Tj 31.428571 0 0 31.428571 0 1512 Tm 12.568182 0 Td 76.893939 Tz (50 ) Tj 31.428571 0 0 31.428571 0 1512 Tm 23.672727 0 Td 79.545455 Tz (55 ) Tj 30 0 0 30 0 1512 Tm 36.4 0 Td 83.333333 Tz (60 ) Tj 42.857143 0 0 42.857143 0 1438.252174 Tm 7.513333 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Pro ) Tj 1.61 0 Td 63.518519 Tz (Pro ) Tj 1.61 0 Td 63.518519 Tz (Met ) Tj 1.656667 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 63.518519 Tz (Val ) Tj 1.656667 0 Td 62.222222 Tz (Lys ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.703333 0 Td 63.518519 Tz (Ile ) Tj 30 0 0 30 0 1413 Tm 10.8 0 Td 83.333333 Tz (65 ) Tj 30 0 0 30 0 1413 Tm 22.433333 0 Td 83.333333 Tz (70 ) Tj 28.571429 0 0 28.571429 0 1414 Tm 35.77 0 Td 87.5 Tz (75 ) Tj 37.142857 0 0 37.142857 0 1308 Tm 8.723077 0 Td 53.846154 Tz (< ) Tj 0.484615 0 Td 70.299145 Tz (210 ) Tj 1.453846 0 Td 53.846154 Tz (> ) Tj 0.888462 0 Td 74.786325 Tz (SEQ ) Tj 1.911538 0 Td 67.307692 Tz (ID ) Tj 1.319231 0 Td 76.282051 Tz (NO ) Tj 1.480769 0 Td 67.307692 Tz (10 ) Tj 31.428571 0 0 31.428571 0 1278 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 79.545455 Tz (20 ) Tj 31.428571 0 0 31.428571 0 1245 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 45.510204 0 0 45.510204 0 1207.263566 Tm 7.119283 0 Td 43.946188 Tz (< ) Tj 0.395516 0 Td 56.153463 Tz (213 ) Tj 1.186547 0 Td 43.946188 Tz (> ) Tj 0.703139 0 Td 60.426009 Tz (ORGANISM ) Tj 3.186099 0 Td 18.310912 Tz (: ) Tj 0.615247 0 Td 63.355755 Tz (Artificial ) Tj 4.284753 0 Td 62.2571 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 1177 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 45.714286 0 0 45.714286 0 1142.504663 Tm 7.0875 0 Td 43.75 Tz (< ) Tj 0.39375 0 Td 55.902778 Tz (223 ) Tj 1.18125 0 Td 43.75 Tz (> ) Tj 0.7 0 Td 62.708333 Tz (OTHER ) Tj 2.340625 0 Td 60.653409 Tz (INFORMATION ) Tj 4.265625 0 Td 18.229167 Tz (: ) Tj 0.678125 0 Td 62.708333 Tz (chemically ) Tj 4.221875 0 Td 62.310606 Tz (synthesized ) Tj 4.528125 0 Td 63.4375 Tz (oligonucleotide ) Tj 40 0 0 40 0 1074 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (400 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 70.833333 Tz (SEQUENCE ) Tj 3.625 0 Td 16.666667 Tz (: ) Tj 0.75 0 Td 62.5 Tz (10 ) Tj 41.428571 0 0 41.428571 0 1010 Tm 7.82069 0 Td 68.793103 Tz (cgcaccaatg ) Tj 4.634483 0 Td 68.793103 Tz (tggagtacag ) Tj 28.571429 0 0 28.571429 0 1014 Tm 54.145 0 Td 90.416667 Tz (20 ) Tj 38.571429 0 0 38.571429 0 907 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.425926 0 Td 64.814815 Tz (11 ) Tj 32.857143 0 0 32.857143 0 879 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 79.468599 Tz (211 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 86.231884 Tz (LENGTH ) Tj 3.347826 0 Td 20.289855 Tz (: ) Tj 0.943478 0 Td 73.550725 Tz (19 ) Tj 32.857143 0 0 32.857143 0 845 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 43.673469 0 0 43.673469 0 807.855212 Tm 7.418692 0 Td 45.794393 Tz (< ) Tj 0.41215 0 Td 58.515057 Tz (213 ) Tj 1.236449 0 Td 45.794393 Tz (> ) Tj 0.73271 0 Td 63.92134 Tz (ORGANISM ) Tj 3.320093 0 Td 19.080997 Tz (: ) Tj 0.641121 0 Td 66.020249 Tz (Artificial ) Tj 4.464953 0 Td 64.875389 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 778 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 47.142857 0 0 47.142857 0 742.495346 Tm 6.872727 0 Td 42.424242 Tz (< ) Tj 0.381818 0 Td 54.208754 Tz (223 ) Tj 1.145455 0 Td 42.424242 Tz (> ) Tj 0.678788 0 Td 60.808081 Tz (OTHER ) Tj 2.269697 0 Td 59.458219 Tz (INFORMATION ) Tj 4.136364 0 Td 17.676768 Tz (: ) Tj 0.657576 0 Td 60.808081 Tz (chemically ) Tj 4.093939 0 Td 60.422406 Tz (synthesized ) Tj 4.390909 0 Td 61.515152 Tz (oligonucleotide ) Tj 38.571429 0 0 38.571429 0 672 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (400 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 73.45679 Tz (SEQUENCE ) Tj 3.759259 0 Td 17.283951 Tz (: ) Tj 0.777778 0 Td 64.814815 Tz (11 ) Tj 41.428571 0 0 41.428571 0 605.52454 Tm 7.82069 0 Td 68.793103 Tz (catagaggcg ) Tj 4.610345 0 Td 69.284802 Tz (gcagtaggg ) Tj 28.571429 0 0 28.571429 0 609 Tm 54.145 0 Td 87.5 Tz (19 ) Tj 38.571429 0 0 38.571429 0 497 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.425926 0 Td 62.654321 Tz (12 ) Tj 34.285714 0 0 34.285714 0 464 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (211 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (LENGTH ) Tj 3.208333 0 Td 19.444444 Tz (: ) Tj 0.904167 0 Td 70.486111 Tz (19 ) Tj 31.428571 0 0 31.428571 0 430 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 46.938776 0 0 46.938776 0 390.862403 Tm 6.902609 0 Td 42.608696 Tz (< ) Tj 0.383478 0 Td 54.444444 Tz (213 ) Tj 1.150435 0 Td 42.608696 Tz (> ) Tj 0.681739 0 Td 58.586957 Tz (ORGANISM ) Tj 3.08913 0 Td 17.753623 Tz (: ) Tj 0.596522 0 Td 61.427536 Tz (Artificial ) Tj 4.154348 0 Td 60.362319 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 359 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 45.714286 0 0 45.714286 0 321.504663 Tm 7.0875 0 Td 43.75 Tz (< ) Tj 0.39375 0 Td 55.902778 Tz (223 ) Tj 1.18125 0 Td 43.75 Tz (> ) Tj 0.7 0 Td 62.708333 Tz (OTHER ) Tj 2.340625 0 Td 60.653409 Tz (INFORMATION ) Tj 4.265625 0 Td 18.229167 Tz (: ) Tj 0.678125 0 Td 62.708333 Tz (chemically ) Tj 4.221875 0 Td 62.310606 Tz (synthesized ) Tj 4.528125 0 Td 63.4375 Tz (oligonucleotide ) Tj 38.571429 0 0 38.571429 0 248 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (400 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 73.45679 Tz (SEQUENCE ) Tj 3.759259 0 Td 17.283951 Tz (: ) Tj 0.777778 0 Td 62.654321 Tz (12 ) Tj ET Q endstream endobj 209 0 obj << /Length 1 >> stream q endstream endobj 210 0 obj << /Length 14199 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3028 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.486111 0 Td 74.537037 Tz (41 ) Tj 58.571429 0 0 58.571429 0 2968 Tm 29.34878 0 Td 68.292683 Tz (42 ) Tj 49.285714 0 0 49.285714 0 2906.056604 Tm 22.947826 0 Td 40.57971 Tz (- ) Tj 0.405797 0 Td 75.147611 Tz (continued ) Tj 42.857143 0 0 42.857143 0 2839.526154 Tm 7.56 0 Td 66.5 Tz (tgaccgtatg ) Tj 4.48 0 Td 66.54321 Tz (agcaaggag ) Tj 30 0 0 30 0 2843 Tm 51.566667 0 Td 83.333333 Tz (19 ) Tj 37.142857 0 0 37.142857 0 2738 Tm 8.723077 0 Td 53.846154 Tz (< ) Tj 0.484615 0 Td 70.299145 Tz (210 ) Tj 1.453846 0 Td 53.846154 Tz (> ) Tj 0.888462 0 Td 74.786325 Tz (SEQ ) Tj 1.911538 0 Td 67.307692 Tz (ID ) Tj 1.319231 0 Td 76.282051 Tz (NO ) Tj 1.480769 0 Td 65.064103 Tz (13 ) Tj 34.285714 0 0 34.285714 0 2708 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (211 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (LENGTH ) Tj 3.208333 0 Td 19.444444 Tz (: ) Tj 0.875 0 Td 72.916667 Tz (20 ) Tj 34.285714 0 0 34.285714 0 2675 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (212 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 80.208333 Tz (TYPE ) Tj 2.1875 0 Td 19.444444 Tz (: ) Tj 0.845833 0 Td 84.259259 Tz (DNA ) Tj 44.285714 0 0 44.285714 0 2638.848544 Tm 7.316129 0 Td 45.16129 Tz (< ) Tj 0.406452 0 Td 57.706093 Tz (213 ) Tj 1.219355 0 Td 45.16129 Tz (> ) Tj 0.722581 0 Td 61.626344 Tz (ORGANISM ) Tj 3.274194 0 Td 18.817204 Tz (: ) Tj 0.632258 0 Td 65.107527 Tz (Artificial ) Tj 4.403226 0 Td 63.978495 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 2608 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 50 0 0 50 0 2569.490702 Tm 6.48 0 Td 40 Tz (< ) Tj 0.36 0 Td 51.111111 Tz (223 ) Tj 1.08 0 Td 40 Tz (> ) Tj 0.64 0 Td 57.333333 Tz (OTHER ) Tj 2.14 0 Td 56.363636 Tz (INFORMATION ) Tj 3.9 0 Td 16.666667 Tz (: ) Tj 0.62 0 Td 57.333333 Tz (chemically ) Tj 3.86 0 Td 56.969697 Tz (synthesized ) Tj 4.14 0 Td 58 Tz (oligonucleotide ) Tj 39.047619 0 0 39.047619 0 2505.729167 Tm 8.297561 0 Td 51.219512 Tz (< ) Tj 0.460976 0 Td 66.869919 Tz (400 ) Tj 1.382927 0 Td 51.219512 Tz (> ) Tj 0.845122 0 Td 72.560976 Tz (SEQUENCE ) Tj 3.713415 0 Td 17.073171 Tz (: ) Tj 0.768293 0 Td 61.890244 Tz (13 ) Tj 42.857143 0 0 42.857143 0 2440 Tm 7.56 0 Td 66.111111 Tz (ccagacaact ) Tj 4.48 0 Td 66.5 Tz (cgcaacttag ) Tj 28.571429 0 0 28.571429 0 2445 Tm 54.11 0 Td 90.416667 Tz (20 ) Tj 40 0 0 40 0 2338 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.375 0 Td 60.416667 Tz (14 ) Tj 31.428571 0 0 31.428571 0 2310 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 79.545455 Tz (20 ) Tj 31.428571 0 0 31.428571 0 2276 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 45.510204 0 0 45.510204 0 2239.263566 Tm 7.119283 0 Td 43.946188 Tz (< ) Tj 0.395516 0 Td 56.153463 Tz (213 ) Tj 1.186547 0 Td 43.946188 Tz (> ) Tj 0.703139 0 Td 60.426009 Tz (ORGANISM ) Tj 3.186099 0 Td 18.310912 Tz (: ) Tj 0.615247 0 Td 63.355755 Tz (Artificial ) Tj 4.284753 0 Td 62.2571 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 2210 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 45.714286 0 0 45.714286 0 2173.504663 Tm 7.0875 0 Td 43.75 Tz (< ) Tj 0.39375 0 Td 55.902778 Tz (223 ) Tj 1.18125 0 Td 43.75 Tz (> ) Tj 0.7 0 Td 62.708333 Tz (OTHER ) Tj 2.340625 0 Td 60.653409 Tz (INFORMATION ) Tj 4.265625 0 Td 18.229167 Tz (: ) Tj 0.678125 0 Td 62.708333 Tz (chemically ) Tj 4.221875 0 Td 62.310606 Tz (synthesized ) Tj 4.528125 0 Td 63.4375 Tz (oligonucleotide ) Tj 40 0 0 40 0 2106 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (400 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 70.833333 Tz (SEQUENCE ) Tj 3.625 0 Td 16.666667 Tz (: ) Tj 0.75 0 Td 60.416667 Tz (14 ) Tj 44.285714 0 0 44.285714 0 2044 Tm 7.316129 0 Td 64.354839 Tz (atggcacacg ) Tj 4.335484 0 Td 63.978495 Tz (ctacattgct ) Tj 28.571429 0 0 28.571429 0 2046 Tm 54.11 0 Td 90.416667 Tz (20 ) Tj 38.571429 0 0 38.571429 0 1940 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.425926 0 Td 64.814815 Tz (15 ) Tj 32.857143 0 0 32.857143 0 1911 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 79.468599 Tz (211 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 86.231884 Tz (LENGTH ) Tj 3.347826 0 Td 20.289855 Tz (: ) Tj 0.913043 0 Td 76.086957 Tz (20 ) Tj 32.857143 0 0 32.857143 0 1877 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 42.653061 0 0 42.653061 0 1840.866019 Tm 7.596172 0 Td 46.889952 Tz (< ) Tj 0.42201 0 Td 59.914939 Tz (213 ) Tj 1.266029 0 Td 46.889952 Tz (> ) Tj 0.750239 0 Td 63.985247 Tz (ORGANISM ) Tj 3.399522 0 Td 19.53748 Tz (: ) Tj 0.656459 0 Td 67.599681 Tz (Artificial ) Tj 4.57177 0 Td 66.427432 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 1810 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 44.285714 0 0 44.285714 0 1775.504663 Tm 7.316129 0 Td 45.16129 Tz (< ) Tj 0.406452 0 Td 57.706093 Tz (223 ) Tj 1.219355 0 Td 45.16129 Tz (> ) Tj 0.722581 0 Td 64.731183 Tz (OTHER ) Tj 2.416129 0 Td 62.609971 Tz (INFORMATION ) Tj 4.403226 0 Td 18.817204 Tz (: ) Tj 0.7 0 Td 64.731183 Tz (chemically ) Tj 4.358065 0 Td 64.320626 Tz (synthesized ) Tj 4.674194 0 Td 65.483871 Tz (oligonucleotide ) Tj 40.238095 0 0 40.238095 0 1705.311203 Tm 8.052071 0 Td 49.704142 Tz (< ) Tj 0.447337 0 Td 64.891519 Tz (400 ) Tj 1.342012 0 Td 49.704142 Tz (> ) Tj 0.820118 0 Td 70.414201 Tz (SEQUENCE ) Tj 3.60355 0 Td 16.568047 Tz (: ) Tj 0.745562 0 Td 62.130178 Tz (15 ) Tj 45.714286 0 0 45.714286 0 1643.502924 Tm 7.065625 0 Td 61.979167 Tz (caacttcgcc ) Tj 4.178125 0 Td 62.708333 Tz (gtcaactaca ) Tj 34.285714 0 0 34.285714 0 1645 Tm 45.0625 0 Td 80.208333 Tz (20 ) Tj 40 0 0 40 0 1539 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.375 0 Td 60.416667 Tz (16 ) Tj 31.428571 0 0 31.428571 0 1510 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 76.893939 Tz (22 ) Tj 31.428571 0 0 31.428571 0 1478 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 46.938776 0 0 46.938776 0 1440.263566 Tm 6.902609 0 Td 42.608696 Tz (< ) Tj 0.383478 0 Td 54.444444 Tz (213 ) Tj 1.150435 0 Td 42.608696 Tz (> ) Tj 0.681739 0 Td 58.586957 Tz (ORGANISM ) Tj 3.08913 0 Td 17.753623 Tz (: ) Tj 0.596522 0 Td 61.427536 Tz (Artificial ) Tj 4.154348 0 Td 60.362319 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 1410 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 47.142857 0 0 47.142857 0 1374.495346 Tm 6.872727 0 Td 42.424242 Tz (< ) Tj 0.381818 0 Td 54.208754 Tz (223 ) Tj 1.145455 0 Td 42.424242 Tz (> ) Tj 0.678788 0 Td 60.808081 Tz (OTHER ) Tj 2.269697 0 Td 59.458219 Tz (INFORMATION ) Tj 4.136364 0 Td 17.676768 Tz (: ) Tj 0.657576 0 Td 60.808081 Tz (chemically ) Tj 4.093939 0 Td 60.422406 Tz (synthesized ) Tj 4.390909 0 Td 61.515152 Tz (oligonucleotide ) Tj 38.571429 0 0 38.571429 0 1306 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (400 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 73.45679 Tz (SEQUENCE ) Tj 3.759259 0 Td 17.283951 Tz (: ) Tj 0.777778 0 Td 62.654321 Tz (16 ) Tj 44.285714 0 0 44.285714 0 1240.639037 Tm 7.316129 0 Td 63.978495 Tz (cccttactct ) Tj 4.335484 0 Td 64.354839 Tz (tccagcttga ) Tj 4.312903 0 Td 62.096774 Tz (ga ) Tj 27.142857 0 0 27.142857 0 1248 Tm 56.957895 0 Td 92.105263 Tz (22 ) Tj 38.571429 0 0 38.571429 0 1141 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.425926 0 Td 64.814815 Tz (17 ) Tj 31.428571 0 0 31.428571 0 1111 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 76.893939 Tz (22 ) Tj 31.428571 0 0 31.428571 0 1078 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 44.285714 0 0 44.285714 0 1039.837838 Tm 7.316129 0 Td 45.16129 Tz (< ) Tj 0.406452 0 Td 57.706093 Tz (213 ) Tj 1.219355 0 Td 45.16129 Tz (> ) Tj 0.722581 0 Td 63.037634 Tz (ORGANISM ) Tj 3.274194 0 Td 18.817204 Tz (: ) Tj 0.632258 0 Td 65.107527 Tz (Artificial ) Tj 4.403226 0 Td 63.978495 Tz (Sequence ) Tj 34.285714 0 0 34.285714 0 1011 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (220 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (FEATURE ) Tj 3.704167 0 Td 19.444444 Tz (: ) Tj 42.857143 0 0 42.857143 0 976.86114 Tm 7.56 0 Td 46.666667 Tz (< ) Tj 0.42 0 Td 59.62963 Tz (223 ) Tj 1.26 0 Td 46.666667 Tz (> ) Tj 0.746667 0 Td 66.888889 Tz (OTHER ) Tj 2.496667 0 Td 64.69697 Tz (INFORMATION ) Tj 4.55 0 Td 19.444444 Tz (: ) Tj 0.723333 0 Td 66.888889 Tz (chemically ) Tj 4.503333 0 Td 66.464646 Tz (synthesized ) Tj 4.83 0 Td 67.666667 Tz (oligonucleotide ) Tj 40 0 0 40 0 907 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (400 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 70.833333 Tz (SEQUENCE ) Tj 3.625 0 Td 16.666667 Tz (: ) Tj 0.75 0 Td 62.5 Tz (17 ) Tj 43.333333 0 0 43.333333 0 844.665775 Tm 7.430769 0 Td 66.153846 Tz (ggaaagaggg ) Tj 4.453846 0 Td 65.769231 Tz (acgtgcttaa ) Tj 4.430769 0 Td 59.615385 Tz (at ) Tj 27.142857 0 0 27.142857 0 849 Tm 56.957895 0 Td 92.105263 Tz (22 ) Tj 40 0 0 40 0 742 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.375 0 Td 62.5 Tz (18 ) Tj 34.285714 0 0 34.285714 0 712 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (211 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (LENGTH ) Tj 3.208333 0 Td 19.444444 Tz (: ) Tj 0.875 0 Td 70.486111 Tz (22 ) Tj 32.857143 0 0 32.857143 0 676 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 39.795918 0 0 39.795918 0 639 Tm 8.141538 0 Td 50.25641 Tz (< ) Tj 0.452308 0 Td 64.216524 Tz (213 ) Tj 1.356923 0 Td 50.25641 Tz (> ) Tj 0.804103 0 Td 69.102564 Tz (ORGANISM ) Tj 3.64359 0 Td 20.940171 Tz (: ) Tj 0.70359 0 Td 72.452991 Tz (Artificial ) Tj 4.9 0 Td 71.196581 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 606 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 47.142857 0 0 47.142857 0 567.495346 Tm 6.872727 0 Td 42.424242 Tz (< ) Tj 0.381818 0 Td 54.208754 Tz (223 ) Tj 1.145455 0 Td 42.424242 Tz (> ) Tj 0.678788 0 Td 60.808081 Tz (OTHER ) Tj 2.269697 0 Td 59.458219 Tz (INFORMATION ) Tj 4.136364 0 Td 17.676768 Tz (: ) Tj 0.657576 0 Td 60.808081 Tz (chemically ) Tj 4.093939 0 Td 60.422406 Tz (synthesized ) Tj 4.390909 0 Td 61.515152 Tz (oligonucleotide ) Tj 38.571429 0 0 38.571429 0 496 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (400 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 73.45679 Tz (SEQUENCE ) Tj 3.759259 0 Td 17.283951 Tz (: ) Tj 0.777778 0 Td 64.814815 Tz (18 ) Tj 41.428571 0 0 41.428571 0 426.5 Tm 7.796552 0 Td 68.793103 Tz (cgcaccccta ) Tj 4.634483 0 Td 68.793103 Tz (aaacccaaaa ) Tj 25.714286 0 0 25.714286 0 430 Tm 27.533333 0 Td 103.703704 Tz (ta ) Tj 27.142857 0 0 27.142857 0 433 Tm 56.957895 0 Td 92.105263 Tz (22 ) Tj 40 0 0 40 0 320 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.375 0 Td 62.5 Tz (19 ) Tj 31.428571 0 0 31.428571 0 290 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 76.893939 Tz (22 ) Tj 32.857143 0 0 32.857143 0 253 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 42.653061 0 0 42.653061 0 214.261122 Tm 7.596172 0 Td 46.889952 Tz (< ) Tj 0.42201 0 Td 59.914939 Tz (213 ) Tj 1.266029 0 Td 46.889952 Tz (> ) Tj 0.750239 0 Td 64.962121 Tz (ORGANISM ) Tj 3.422967 0 Td 19.53748 Tz (: ) Tj 0.633014 0 Td 67.599681 Tz (Artificial ) Tj 4.57177 0 Td 66.427432 Tz (Sequence ) Tj ET Q endstream endobj 211 0 obj << /Length 1 >> stream q endstream endobj 212 0 obj << /Length 14484 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3028 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.486111 0 Td 77.777778 Tz (43 ) Tj 55.714286 0 0 55.714286 0 2969 Tm 30.853846 0 Td 71.794872 Tz (44 ) Tj 47.857143 0 0 47.857143 0 2908.056604 Tm 23.632836 0 Td 41.791045 Tz (- ) Tj 0.41791 0 Td 77.390824 Tz (continued ) Tj 32.857143 0 0 32.857143 0 2840 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 79.468599 Tz (220 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 86.231884 Tz (FEATURE ) Tj 3.865217 0 Td 20.289855 Tz (: ) Tj 45.714286 0 0 45.714286 0 2806.504663 Tm 7.0875 0 Td 43.75 Tz (< ) Tj 0.39375 0 Td 55.902778 Tz (223 ) Tj 1.18125 0 Td 43.75 Tz (> ) Tj 0.7 0 Td 62.708333 Tz (OTHER ) Tj 2.340625 0 Td 60.653409 Tz (INFORMATION ) Tj 4.265625 0 Td 18.229167 Tz (: ) Tj 0.678125 0 Td 62.708333 Tz (chemically ) Tj 4.221875 0 Td 62.310606 Tz (synthesized ) Tj 4.528125 0 Td 63.4375 Tz (oligonucleotide ) Tj 42.857143 0 0 42.857143 0 2736 Tm 7.56 0 Td 46.666667 Tz (< ) Tj 0.42 0 Td 60.925926 Tz (400 ) Tj 1.26 0 Td 46.666667 Tz (> ) Tj 0.77 0 Td 66.111111 Tz (SEQUENCE ) Tj 3.383333 0 Td 15.555556 Tz (: ) Tj 0.7 0 Td 58.333333 Tz (19 ) Tj 42.857143 0 0 42.857143 0 2675.485255 Tm 7.56 0 Td 66.111111 Tz (caactgcatc ) Tj 4.48 0 Td 66.5 Tz (tgttctgaca ) Tj 4.48 0 Td 62.222222 Tz (ca ) Tj 28.571429 0 0 28.571429 0 2678 Tm 54.11 0 Td 87.5 Tz (22 ) Tj 40 0 0 40 0 2572 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.35 0 Td 64.583333 Tz (20 ) Tj 32.857143 0 0 32.857143 0 2543 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 79.468599 Tz (211 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 86.231884 Tz (LENGTH ) Tj 3.347826 0 Td 20.289855 Tz (: ) Tj 0.913043 0 Td 73.550725 Tz (22 ) Tj 32.857143 0 0 32.857143 0 2509 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 43.877551 0 0 43.877551 0 2471.592664 Tm 7.384186 0 Td 45.581395 Tz (< ) Tj 0.410233 0 Td 58.242894 Tz (213 ) Tj 1.230698 0 Td 45.581395 Tz (> ) Tj 0.729302 0 Td 63.624031 Tz (ORGANISM ) Tj 3.304651 0 Td 18.992248 Tz (: ) Tj 0.63814 0 Td 65.713178 Tz (Artificial ) Tj 4.444186 0 Td 64.573643 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 2442 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 48.571429 0 0 48.571429 0 2406.5 Tm 6.670588 0 Td 41.176471 Tz (< ) Tj 0.370588 0 Td 52.614379 Tz (223 ) Tj 1.111765 0 Td 41.176471 Tz (> ) Tj 0.658824 0 Td 59.019608 Tz (OTHER ) Tj 2.202941 0 Td 57.397504 Tz (INFORMATION ) Tj 4.014706 0 Td 17.156863 Tz (: ) Tj 0.638235 0 Td 59.019608 Tz (chemically ) Tj 3.973529 0 Td 58.645276 Tz (synthesized ) Tj 4.261765 0 Td 59.705882 Tz (oligonucleotide ) Tj 37.142857 0 0 37.142857 0 2339 Tm 8.723077 0 Td 53.846154 Tz (< ) Tj 0.484615 0 Td 70.299145 Tz (400 ) Tj 1.453846 0 Td 53.846154 Tz (> ) Tj 0.888462 0 Td 76.282051 Tz (SEQUENCE ) Tj 3.903846 0 Td 17.948718 Tz (: ) Tj 0.780769 0 Td 69.551282 Tz (20 ) Tj 38.571429 0 0 38.571429 0 2274.5 Tm 8.374074 0 Td 73.45679 Tz (acatgaccac ) Tj 4.977778 0 Td 73.45679 Tz (cacaacaaac ) Tj 22.857143 0 0 22.857143 0 2279 Tm 30.93125 0 Td 116.666667 Tz (aa ) Tj 27.142857 0 0 27.142857 0 2280 Tm 56.957895 0 Td 92.105263 Tz (22 ) Tj 38.571429 0 0 38.571429 0 2173 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.4 0 Td 66.975309 Tz (21 ) Tj 33.333333 0 0 33.333333 0 2142.838235 Tm 9.72 0 Td 50 Tz (< ) Tj 0.51 0 Td 83.333333 Tz (211 ) Tj 1.74 0 Td 45 Tz (> ) Tj 0.9 0 Td 85 Tz (LENGTH ) Tj 3.3 0 Td 20 Tz (: ) Tj 0.9 0 Td 72.5 Tz (22 ) Tj 32.857143 0 0 32.857143 0 2110 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 44.081633 0 0 44.081633 0 2074.258687 Tm 7.35 0 Td 45.37037 Tz (< ) Tj 0.408333 0 Td 57.973251 Tz (213 ) Tj 1.225 0 Td 45.37037 Tz (> ) Tj 0.725926 0 Td 63.329475 Tz (ORGANISM ) Tj 3.289352 0 Td 18.904321 Tz (: ) Tj 0.635185 0 Td 65.408951 Tz (Artificial ) Tj 4.423611 0 Td 64.274691 Tz (Sequence ) Tj 30.285714 0 0 30.285714 0 2044.020619 Tm 10.665094 0 Td 66.037736 Tz (< ) Tj 0.59434 0 Td 86.215933 Tz (220 ) Tj 1.783019 0 Td 66.037736 Tz (> ) Tj 1.089623 0 Td 93.553459 Tz (FEATURE ) Tj 4.193396 0 Td 22.012579 Tz (: ) Tj 48.571429 0 0 48.571429 0 2006.5 Tm 6.670588 0 Td 41.176471 Tz (< ) Tj 0.370588 0 Td 52.614379 Tz (223 ) Tj 1.111765 0 Td 41.176471 Tz (> ) Tj 0.658824 0 Td 59.019608 Tz (OTHER ) Tj 2.202941 0 Td 57.397504 Tz (INFORMATION ) Tj 4.055882 0 Td 17.156863 Tz (: ) Tj 0.597059 0 Td 59.019608 Tz (chemically ) Tj 3.973529 0 Td 58.645276 Tz (synthesized ) Tj 4.261765 0 Td 59.705882 Tz (oligonucleotide ) Tj 38.571429 0 0 38.571429 0 1939 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (400 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 73.45679 Tz (SEQUENCE ) Tj 3.759259 0 Td 17.283951 Tz (: ) Tj 0.751852 0 Td 66.975309 Tz (21 ) Tj 42.857143 0 0 42.857143 0 1878 Tm 7.56 0 Td 66.111111 Tz (cctcacaggt ) Tj 4.456667 0 Td 66.5 Tz (gttcttcttt ) Tj 4.48 0 Td 64.166667 Tz (gg ) Tj 27.142857 0 0 27.142857 0 1881 Tm 56.957895 0 Td 92.105263 Tz (22 ) Tj 38.571429 0 0 38.571429 0 1774 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.4 0 Td 64.814815 Tz (22 ) Tj 32.857143 0 0 32.857143 0 1745 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 79.468599 Tz (211 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 86.231884 Tz (LENGTH ) Tj 3.347826 0 Td 20.289855 Tz (: ) Tj 0.913043 0 Td 79.468599 Tz (480 ) Tj 31.428571 0 0 31.428571 0 1710 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 37.142857 0 0 37.142857 0 1676 Tm 8.723077 0 Td 53.846154 Tz (< ) Tj 0.484615 0 Td 68.803419 Tz (213 ) Tj 1.453846 0 Td 53.846154 Tz (> ) Tj 0.861538 0 Td 74.599359 Tz (ORGANISM ) Tj 3.903846 0 Td 22.435897 Tz (: ) Tj 0.807692 0 Td 77.403846 Tz (Triticum ) Tj 4.253846 0 Td 76.842949 Tz (aestivum ) Tj 37.619048 0 0 37.619048 0 1606.605809 Tm 8.612658 0 Td 53.164557 Tz (< ) Tj 0.478481 0 Td 69.409283 Tz (400 ) Tj 1.435443 0 Td 53.164557 Tz (> ) Tj 0.877215 0 Td 75.316456 Tz (SEQUENCE ) Tj 3.85443 0 Td 17.721519 Tz (: ) Tj 0.770886 0 Td 66.455696 Tz (22 ) Tj 45.714286 0 0 45.714286 0 1539.678049 Tm 7.0875 0 Td 61.979167 Tz (tttcaccaat ) Tj 4.2 0 Td 62.34375 Tz (aaagatggag ) Tj 4.2 0 Td 61.979167 Tz (ttgtccgtat ) Tj 4.2 0 Td 61.979167 Tz (aaaatccaac ) Tj 4.2 0 Td 62.708333 Tz (tatttcgaca ) Tj 4.221875 0 Td 62.708333 Tz (tgttttggag ) Tj 34.285714 0 0 34.285714 0 1544 Tm 45.091667 0 Td 77.777778 Tz (60 ) Tj 45.714286 0 0 45.714286 0 1475.826511 Tm 7.065625 0 Td 62.708333 Tz (gcgaagccca ) Tj 4.221875 0 Td 61.979167 Tz (aattggatct ) Tj 4.178125 0 Td 62.34375 Tz (gggctgattc ) Tj 4.221875 0 Td 61.979167 Tz (aactgacacc ) Tj 4.2 0 Td 62.708333 Tz (acccacaaca ) Tj 4.221875 0 Td 62.34375 Tz (accgtgatac ) Tj 30 0 0 30 0 1479 Tm 51 0 Td 87.037037 Tz (120 ) Tj 44.285714 0 0 44.285714 0 1411 Tm 7.316129 0 Td 64.354839 Tz (attattcaag ) Tj 4.312903 0 Td 64.731183 Tz (gtgaccactg ) Tj 4.335484 0 Td 64.354839 Tz (ggcccgactt ) Tj 4.358065 0 Td 64.354839 Tz (cattgctctg ) Tj 4.335484 0 Td 64.731183 Tz (cgaaacttgg ) Tj 4.335484 0 Td 65.107527 Tz (gcaacaacaa ) Tj 30 0 0 30 0 1411 Tm 51.033333 0 Td 87.037037 Tz (180 ) Tj 41.428571 0 0 41.428571 0 1344 Tm 7.82069 0 Td 68.793103 Tz (tttctgcaaa ) Tj 4.634483 0 Td 68.793103 Tz (aggttaacca ) Tj 4.634483 0 Td 68.793103 Tz (cagaagggaa ) Tj 4.610345 0 Td 68.793103 Tz (gtatgattgc ) Tj 4.658621 0 Td 69.195402 Tz (ctcaatgctg ) Tj 4.658621 0 Td 68.793103 Tz (ctgttggttc ) Tj 34.285714 0 0 34.285714 0 1345 Tm 44.595833 0 Td 77.777778 Tz (240 ) Tj 41.428571 0 0 41.428571 0 1277 Tm 7.82069 0 Td 68.390805 Tz (catcacagct ) Tj 4.610345 0 Td 69.195402 Tz (gaagtaaaaa ) Tj 4.658621 0 Td 68.390805 Tz (tgcggtgcat ) Tj 4.634483 0 Td 68.390805 Tz (tgaaccaatt ) Tj 4.610345 0 Td 69.597701 Tz (gtttctcgag ) Tj 4.682759 0 Td 69.195402 Tz (acatctatga ) Tj 28.571429 0 0 28.571429 0 1279 Tm 53.55 0 Td 93.333333 Tz (300 ) Tj 45.714286 0 0 45.714286 0 1208.841285 Tm 7.0875 0 Td 61.979167 Tz (tgttgatttt ) Tj 4.2 0 Td 62.34375 Tz (cgcctaggtg ) Tj 4.2 0 Td 61.979167 Tz (aagctaagat ) Tj 4.2 0 Td 61.979167 Tz (ctacaccaat ) Tj 4.178125 0 Td 63.072917 Tz (ggtattgagg ) Tj 4.221875 0 Td 63.072917 Tz (gccttgatag ) Tj 30 0 0 30 0 1212 Tm 51 0 Td 88.888889 Tz (360 ) Tj 45.714286 0 0 45.714286 0 1142.34375 Tm 7.065625 0 Td 61.979167 Tz (tcaaattgtt ) Tj 4.178125 0 Td 62.708333 Tz (gaaaacatga ) Tj 4.221875 0 Td 61.979167 Tz (ccaccacaac ) Tj 41.428571 0 0 41.428571 0 1141.003906 Tm 21.724138 0 Td 68.390805 Tz (aaacaaaacc ) Tj 4.634483 0 Td 68.793103 Tz (aaaatgatct ) Tj 4.658621 0 Td 68.793103 Tz (tcacatacac ) Tj 28.571429 0 0 28.571429 0 1147 Tm 53.55 0 Td 93.333333 Tz (420 ) Tj 50 0 0 50 0 1077 Tm 6.48 0 Td 56.666667 Tz (aaataccgtc ) Tj 3.84 0 Td 56.666667 Tz (cagagtacct ) Tj 3.82 0 Td 57 Tz (ggagttctac ) Tj 3.86 0 Td 57 Tz (tgtttcattg ) Tj 3.84 0 Td 57.333333 Tz (aagattggcg ) Tj 3.86 0 Td 57.333333 Tz (tcaagaccaa ) Tj 32.857143 0 0 32.857143 0 1078 Tm 46.534783 0 Td 82.850242 Tz (480 ) Tj 38.571429 0 0 38.571429 0 974 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.4 0 Td 64.814815 Tz (23 ) Tj 31.428571 0 0 31.428571 0 945 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 83.080808 Tz (480 ) Tj 31.428571 0 0 31.428571 0 911 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.922727 0 Td 91.919192 Tz (DNA ) Tj 42.653061 0 0 42.653061 0 875.266019 Tm 7.596172 0 Td 46.889952 Tz (< ) Tj 0.42201 0 Td 59.914939 Tz (213 ) Tj 1.266029 0 Td 46.889952 Tz (> ) Tj 0.750239 0 Td 63.985247 Tz (ORGANISM ) Tj 3.399522 0 Td 19.53748 Tz (: ) Tj 0.656459 0 Td 67.599681 Tz (Artificial ) Tj 4.57177 0 Td 66.427432 Tz (Sequence ) Tj 34.285714 0 0 34.285714 0 844 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (220 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (FEATURE ) Tj 3.704167 0 Td 19.444444 Tz (: ) Tj 44.285714 0 0 44.285714 0 806.705403 Tm 7.316129 0 Td 45.16129 Tz (< ) Tj 0.406452 0 Td 57.706093 Tz (223 ) Tj 1.219355 0 Td 45.16129 Tz (> ) Tj 0.722581 0 Td 64.731183 Tz (OTHER ) Tj 2.416129 0 Td 62.952102 Tz (INFORMATION ) Tj 4.403226 0 Td 18.817204 Tz (: ) Tj 0.7 0 Td 64.731183 Tz (chemically ) Tj 4.290323 0 Td 65.053763 Tz (mutated ) Tj 3.183871 0 Td 64.919355 Tz (Triticum ) Tj 3.567742 0 Td 64.919355 Tz (aestivum ) Tj 3.545161 0 Td 63.037634 Tz (gene ) Tj 34.285714 0 0 34.285714 0 779 Tm 12.5125 0 Td 82.03125 Tz (sequence ) Tj 38.571429 0 0 38.571429 0 708 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (400 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 73.45679 Tz (SEQUENCE ) Tj 3.759259 0 Td 17.283951 Tz (: ) Tj 0.751852 0 Td 64.814815 Tz (23 ) Tj 44.285714 0 0 44.285714 0 638.678049 Tm 7.316129 0 Td 63.978495 Tz (tttcaccaat ) Tj 4.335484 0 Td 64.354839 Tz (aaagatggag ) Tj 4.335484 0 Td 63.978495 Tz (ttgtccgtat ) Tj 4.335484 0 Td 63.978495 Tz (aaaatccaac ) Tj 4.335484 0 Td 64.731183 Tz (tatttcgaca ) Tj 4.358065 0 Td 64.731183 Tz (tgttttggag ) Tj 30 0 0 30 0 644 Tm 51.566667 0 Td 83.333333 Tz (60 ) Tj 47.142857 0 0 47.142857 0 569.826511 Tm 6.851515 0 Td 60.808081 Tz (gcgaagcoca ) Tj 4.093939 0 Td 60.10101 Tz (aattggatct ) Tj 4.051515 0 Td 60.454545 Tz (gggctgatto ) Tj 4.093939 0 Td 60.10101 Tz (aactgacacc ) Tj 4.072727 0 Td 60.808081 Tz (acccacaaca ) Tj 4.093939 0 Td 60.454545 Tz (accgtgatac ) Tj 28.571429 0 0 28.571429 0 573 Tm 53.55 0 Td 91.388889 Tz (120 ) Tj 42.857143 0 0 42.857143 0 499 Tm 7.56 0 Td 66.5 Tz (attattcaag ) Tj 4.456667 0 Td 66.888889 Tz (gtgaccactg ) Tj 4.48 0 Td 66.5 Tz (ggcccgactt ) Tj 4.503333 0 Td 66.5 Tz (cattgctctg ) Tj 4.48 0 Td 66.888889 Tz (cgaaacttgg ) Tj 4.48 0 Td 67.277778 Tz (gcaacaacaa ) Tj 30 0 0 30 0 501 Tm 51 0 Td 87.037037 Tz (180 ) Tj 42.857143 0 0 42.857143 0 428 Tm 7.56 0 Td 66.5 Tz (tttctgcaaa ) Tj 4.48 0 Td 66.5 Tz (aggttaacca ) Tj 4.48 0 Td 66.111111 Tz (cagaagggaa ) Tj 4.573333 0 Td 66.111111 Tz (gtatgattgc ) Tj 4.386667 0 Td 70.777778 Tz (ctcaatgctgctgttggttc ) Tj 32.857143 0 0 32.857143 0 429 Tm 46.534783 0 Td 81.15942 Tz (240 ) Tj 40 0 0 40 0 358 Tm 8.1 0 Td 70.833333 Tz (catcacagct ) Tj 4.775 0 Td 71.666667 Tz (gaagtaaaaa ) Tj 44.285714 0 0 44.285714 0 358 Tm 16.46129 0 Td 62.305854 Tz (gcggtgcat ) Tj 3.86129 0 Td 63.978495 Tz (tgaaccaatt ) Tj 4.312903 0 Td 65.107527 Tz (gtttctcgag ) Tj 4.380645 0 Td 64.731183 Tz (acatctatga ) Tj 31.428571 0 0 31.428571 0 359 Tm 48.65 0 Td 84.848485 Tz (300 ) Tj 44.285714 0 0 44.285714 0 286.841285 Tm 7.316129 0 Td 63.978495 Tz (tgttgatttt ) Tj 4.335484 0 Td 64.354839 Tz (cgcctaggtg ) Tj 4.335484 0 Td 63.978495 Tz (aagctaagat ) Tj 4.335484 0 Td 63.978495 Tz (ctacaccaat ) Tj 4.312903 0 Td 65.107527 Tz (ggtattgagg ) Tj 4.358065 0 Td 65.107527 Tz (gccttgatag ) Tj 31.428571 0 0 31.428571 0 290 Tm 48.65 0 Td 86.616162 Tz (360 ) Tj 48.571429 0 0 48.571429 0 212.675781 Tm 6.670588 0 Td 58.333333 Tz (tcaaattgtt ) Tj 3.932353 0 Td 59.019608 Tz (gaaaacatga ) Tj 3.973529 0 Td 58.333333 Tz (ccaccacaac ) Tj 40 0 0 40 0 215.003906 Tm 22.5 0 Td 70.833333 Tz (aaacaaaacc ) Tj 4.8 0 Td 71.25 Tz (aaaatgatct ) Tj 4.825 0 Td 71.25 Tz (tcacatacac ) Tj 32.857143 0 0 32.857143 0 218 Tm 46.565217 0 Td 81.15942 Tz (420 ) Tj ET Q endstream endobj 213 0 obj << /Length 1 >> stream q endstream endobj 214 0 obj << /Length 18554 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3028 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 52.857143 0 0 52.857143 0 2971 Tm 14.094595 0 Td 75.675676 Tz (45 ) Tj 54.285714 0 0 54.285714 0 2971 Tm 31.665789 0 Td 73.684211 Tz (46 ) Tj 47.857143 0 0 47.857143 0 2907.056604 Tm 23.632836 0 Td 41.791045 Tz (- ) Tj 0.41791 0 Td 77.390824 Tz (continued ) Tj 47.142857 0 0 47.142857 0 2807 Tm 6.872727 0 Td 60.10101 Tz (aaataccgtc ) Tj 4.072727 0 Td 60.10101 Tz (cagagtacct ) Tj 4.072727 0 Td 60.10101 Tz (agagttctac ) Tj 4.072727 0 Td 60.454545 Tz (tgtttcattg ) Tj 4.072727 0 Td 60.808081 Tz (aagattggcg ) Tj 4.093939 0 Td 60.808081 Tz (tcaagaccaa ) Tj 31.428571 0 0 31.428571 0 2810 Tm 48.65 0 Td 84.848485 Tz (480 ) Tj 38.571429 0 0 38.571429 0 2705 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.4 0 Td 64.814815 Tz (24 ) Tj 34.285714 0 0 34.285714 0 2676 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (211 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (LENGTH ) Tj 3.208333 0 Td 19.444444 Tz (: ) Tj 0.875 0 Td 76.157407 Tz (480 ) Tj 32.857143 0 0 32.857143 0 2642 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 77.777778 Tz (212 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 83.695652 Tz (TYPE ) Tj 2.282609 0 Td 20.289855 Tz (: ) Tj 0.882609 0 Td 87.922705 Tz (DNA ) Tj 43.469388 0 0 43.469388 0 2604.649805 Tm 7.453521 0 Td 46.00939 Tz (< ) Tj 0.414085 0 Td 58.789776 Tz (213 ) Tj 1.242254 0 Td 46.00939 Tz (> ) Tj 0.73615 0 Td 62.304382 Tz (ORGANISM ) Tj 3.335681 0 Td 19.170579 Tz (: ) Tj 0.644131 0 Td 66.330203 Tz (Artificial ) Tj 4.485915 0 Td 65.179969 Tz (Sequence ) Tj 31.428571 0 0 31.428571 0 2575 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (220 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (FEATURE ) Tj 4.040909 0 Td 21.212121 Tz (: ) Tj 47.142857 0 0 47.142857 0 2535.701933 Tm 6.872727 0 Td 42.424242 Tz (< ) Tj 0.381818 0 Td 54.208754 Tz (223 ) Tj 1.145455 0 Td 42.424242 Tz (> ) Tj 0.678788 0 Td 60.808081 Tz (OTHER ) Tj 2.269697 0 Td 59.779614 Tz (INFORMATION ) Tj 4.136364 0 Td 17.676768 Tz (: ) Tj 0.657576 0 Td 60.808081 Tz (chemically ) Tj 4.030303 0 Td 61.111111 Tz (mutated ) Tj 2.990909 0 Td 60.984848 Tz (Triticum ) Tj 3.351515 0 Td 60.984848 Tz (aestivum ) Tj 3.330303 0 Td 59.217172 Tz (gene ) Tj 35.714286 0 0 35.714286 0 2509 Tm 12.012 0 Td 78.75 Tz (sequence ) Tj 37.619048 0 0 37.619048 0 2438.294606 Tm 8.612658 0 Td 53.164557 Tz (< ) Tj 0.478481 0 Td 69.409283 Tz (400 ) Tj 1.435443 0 Td 53.164557 Tz (> ) Tj 0.877215 0 Td 75.316456 Tz (SEQUENCE ) Tj 3.85443 0 Td 17.721519 Tz (: ) Tj 0.770886 0 Td 66.455696 Tz (24 ) Tj 45.714286 0 0 45.714286 0 2372.678049 Tm 7.0875 0 Td 61.979167 Tz (tttcaccaat ) Tj 4.2 0 Td 62.34375 Tz (aaagatggag ) Tj 4.2 0 Td 61.979167 Tz (ttgtccgtat ) Tj 4.2 0 Td 61.979167 Tz (aaaatccaac ) Tj 4.2 0 Td 62.708333 Tz (tatttcgaca ) Tj 4.221875 0 Td 62.708333 Tz (tgttttgaag ) Tj 28.571429 0 0 28.571429 0 2379 Tm 54.145 0 Td 87.5 Tz (60 ) Tj 45.714286 0 0 45.714286 0 2307.826511 Tm 7.065625 0 Td 62.708333 Tz (gcgaagccca ) Tj 4.221875 0 Td 61.979167 Tz (aattggatct ) Tj 4.178125 0 Td 62.34375 Tz (gggctgattc ) Tj 4.221875 0 Td 61.979167 Tz (aactgacacc ) Tj 4.2 0 Td 62.708333 Tz (acccacaaca ) Tj 4.221875 0 Td 62.34375 Tz (accgtgatac ) Tj 30 0 0 30 0 2311 Tm 50.966667 0 Td 90.740741 Tz (120 ) Tj 44.285714 0 0 44.285714 0 2243 Tm 7.316129 0 Td 64.354839 Tz (attattcaag ) Tj 4.312903 0 Td 64.731183 Tz (gtgaccactg ) Tj 4.335484 0 Td 64.354839 Tz (ggcccgactt ) Tj 4.358065 0 Td 64.354839 Tz (cattgctctg ) Tj 4.335484 0 Td 64.731183 Tz (cgaaacttgg ) Tj 4.335484 0 Td 65.107527 Tz (gcaacaacaa ) Tj 28.571429 0 0 28.571429 0 2244 Tm 53.585 0 Td 91.388889 Tz (180 ) Tj 41.428571 0 0 41.428571 0 2176 Tm 7.82069 0 Td 68.793103 Tz (tttctgcaaa ) Tj 4.634483 0 Td 68.793103 Tz (aggttaacca ) Tj 4.634483 0 Td 68.793103 Tz (cagaagggaa ) Tj 4.610345 0 Td 68.793103 Tz (gtatgattgc ) Tj 4.658621 0 Td 69.195402 Tz (ctcaatgctg ) Tj 4.658621 0 Td 68.793103 Tz (ctgttggttc ) Tj 31.428571 0 0 31.428571 0 2177 Tm 48.681818 0 Td 84.848485 Tz (240 ) Tj 41.428571 0 0 41.428571 0 2110 Tm 7.82069 0 Td 68.390805 Tz (catcacagct ) Tj 4.610345 0 Td 69.195402 Tz (gaagtaaaaa ) Tj 4.658621 0 Td 68.390805 Tz (tgcggtgcat ) Tj 4.634483 0 Td 68.390805 Tz (tgaaccaatt ) Tj 4.610345 0 Td 69.597701 Tz (gtttctcgag ) Tj 4.682759 0 Td 69.195402 Tz (acatctatga ) Tj 30 0 0 30 0 2111 Tm 51 0 Td 88.888889 Tz (300 ) Tj 44.285714 0 0 44.285714 0 2040.841285 Tm 7.316129 0 Td 63.978495 Tz (tgttgatttt ) Tj 4.335484 0 Td 64.354839 Tz (cgcctaggtg ) Tj 4.335484 0 Td 63.978495 Tz (aagctaagat ) Tj 4.335484 0 Td 63.978495 Tz (ctacaccaat ) Tj 4.312903 0 Td 65.107527 Tz (ggtattgagg ) Tj 4.358065 0 Td 65.107527 Tz (gccttgatag ) Tj 30 0 0 30 0 2046 Tm 50.966667 0 Td 88.888889 Tz (360 ) Tj 45.714286 0 0 45.714286 0 1972.675781 Tm 7.0875 0 Td 61.979167 Tz (tcaaattgtt ) Tj 4.178125 0 Td 62.708333 Tz (gaaaacatga ) Tj 4.221875 0 Td 61.979167 Tz (ccaccacaac ) Tj 38.571429 0 0 38.571429 0 1974.003906 Tm 23.333333 0 Td 73.45679 Tz (aaacaaaacc ) Tj 4.977778 0 Td 73.888889 Tz (aaaatgatct ) Tj 5.003704 0 Td 73.888889 Tz (tcacatacac ) Tj 28.571429 0 0 28.571429 0 1979 Tm 53.515 0 Td 93.333333 Tz (420 ) Tj 44.285714 0 0 44.285714 0 1912 Tm 7.316129 0 Td 63.978495 Tz (aaataccgtc ) Tj 4.335484 0 Td 63.978495 Tz (cagagtacct ) Tj 4.312903 0 Td 64.354839 Tz (ggagttctac ) Tj 4.358065 0 Td 64.354839 Tz (tgtttcattg ) Tj 4.335484 0 Td 64.731183 Tz (aagattggcg ) Tj 4.358065 0 Td 64.731183 Tz (tcaagaccaa ) Tj 30 0 0 30 0 1913 Tm 51 0 Td 88.888889 Tz (480 ) Tj 37.142857 0 0 37.142857 0 1808 Tm 8.723077 0 Td 53.846154 Tz (< ) Tj 0.484615 0 Td 70.299145 Tz (210 ) Tj 1.453846 0 Td 53.846154 Tz (> ) Tj 0.888462 0 Td 74.786325 Tz (SEQ ) Tj 1.911538 0 Td 67.307692 Tz (ID ) Tj 1.319231 0 Td 76.282051 Tz (NO ) Tj 1.453846 0 Td 69.551282 Tz (25 ) Tj 32.857143 0 0 32.857143 0 1778 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 79.468599 Tz (211 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 86.231884 Tz (LENGTH ) Tj 3.347826 0 Td 20.289855 Tz (: ) Tj 0.913043 0 Td 79.468599 Tz (418 ) Tj 31.428571 0 0 31.428571 0 1745 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 86.616162 Tz (PRT ) Tj 40 0 0 40 0 1708 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 63.888889 Tz (213 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.8 0 Td 69.791667 Tz (ORGANISM ) Tj 3.625 0 Td 20.833333 Tz (: ) Tj 0.75 0 Td 71.875 Tz (Triticum ) Tj 3.95 0 Td 71.354167 Tz (aestivum ) Tj 40 0 0 40 0 1639 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (400 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 70.833333 Tz (SEQUENCE ) Tj 3.625 0 Td 16.666667 Tz (: ) Tj 0.725 0 Td 64.583333 Tz (25 ) Tj 42.857143 0 0 42.857143 0 1573.345865 Tm 7.513333 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 63.518519 Tz (His ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 66.111111 Tz (Asn ) Tj 1.61 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 64.814815 Tz (Tyr ) Tj 1.656667 0 Td 63.518519 Tz (Trp ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 27.142857 0 0 27.142857 0 1545 Tm 11.973684 0 Td 73.684211 Tz (1 ) Tj 30 0 0 30 0 1544 Tm 20.133333 0 Td 66.666667 Tz (5 ) Tj 28.571429 0 0 28.571429 0 1546 Tm 33.355 0 Td 84.583333 Tz (10 ) Tj 27.142857 0 0 27.142857 0 1547 Tm 48.005263 0 Td 89.035088 Tz (15 ) Tj 42.857143 0 0 42.857143 0 1472.892365 Tm 7.56 0 Td 63.518519 Tz (Pro ) Tj 1.61 0 Td 66.111111 Tz (Gin ) Tj 1.633333 0 Td 66.111111 Tz (Gin ) Tj 1.61 0 Td 66.111111 Tz (Arg ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 64.814815 Tz (Arg ) Tj 1.656667 0 Td 63.518519 Tz (Trp ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.656667 0 Td 63.518519 Tz (Ile ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 63.518519 Tz (Thr ) Tj 30 0 0 30 0 1445 Tm 17.8 0 Td 83.333333 Tz (20 ) Tj 30 0 0 30 0 1445 Tm 29.4 0 Td 83.333333 Tz (25 ) Tj 28.571429 0 0 28.571429 0 1446 Tm 43.085 0 Td 87.5 Tz (30 ) Tj 41.428571 0 0 41.428571 0 1372.105263 Tm 7.772414 0 Td 68.390805 Tz (Ala ) Tj 1.689655 0 Td 69.731801 Tz (Asn ) Tj 1.713793 0 Td 68.390805 Tz (Glu ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Glu ) Tj 1.689655 0 Td 68.390805 Tz (Glu ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 64.367816 Tz (Lys ) Tj 1.689655 0 Td 64.367816 Tz (Pro ) Tj 1.665517 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 64.367816 Tz (Cys ) Tj 1.689655 0 Td 67.049808 Tz (Thr ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 65.708812 Tz (Phe ) Tj 32.857143 0 0 32.857143 0 1344 Tm 14.121739 0 Td 76.086957 Tz (35 ) Tj 31.428571 0 0 31.428571 0 1345 Tm 25.804545 0 Td 84.848485 Tz (40 ) Tj 30 0 0 30 0 1346 Tm 38.7 0 Td 83.333333 Tz (45 ) Tj 42.857143 0 0 42.857143 0 1273.277427 Tm 7.56 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Pro ) Tj 1.563333 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 62.222222 Tz (Ser ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.586667 0 Td 67.407407 Tz (Arg ) Tj 1.703333 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 28.571429 0 0 28.571429 0 1247 Tm 13.79 0 Td 84.583333 Tz (50 ) Tj 28.571429 0 0 28.571429 0 1247 Tm 26.005 0 Td 87.5 Tz (55 ) Tj 27.142857 0 0 27.142857 0 1248 Tm 40.231579 0 Td 92.105263 Tz (60 ) Tj 42.857143 0 0 42.857143 0 1172.991935 Tm 9.193333 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Gin ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.68 0 Td 62.222222 Tz (Cys ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 64.814815 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 63.518519 Tz (Met ) Tj 31.428571 0 0 31.428571 0 1146 Tm 10.309091 0 Td 79.545455 Tz (65 ) Tj 30 0 0 30 0 1147 Tm 22.433333 0 Td 83.333333 Tz (70 ) Tj 28.571429 0 0 28.571429 0 1147 Tm 35.77 0 Td 87.5 Tz (75 ) Tj 30 0 0 30 0 1145 Tm 45.8 0 Td 80.555556 Tz (80 ) Tj 42.857143 0 0 42.857143 0 1073.889586 Tm 7.56 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.656667 0 Td 63.518519 Tz (Pro ) Tj 1.61 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.563333 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.656667 0 Td 64.814815 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 67.407407 Tz (Asp ) Tj 1.68 0 Td 66.111111 Tz (Gln ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 34.285714 0 0 34.285714 0 1043 Tm 17.5875 0 Td 77.777778 Tz (85 ) Tj 32.857143 0 0 32.857143 0 1045 Tm 39.656522 0 Td 78.623188 Tz (95 ) Tj 32.857143 0 0 32.857143 0 1045 Tm 28.973913 0 Td 81.15942 Tz (90 ) Tj 41.428571 0 0 41.428571 0 972.761194 Tm 7.772414 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.665517 0 Td 68.390805 Tz (Ala ) Tj 1.737931 0 Td 65.708812 Tz (Phe ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.689655 0 Td 65.708812 Tz (Val ) Tj 1.713793 0 Td 65.708812 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Glu ) Tj 1.689655 0 Td 69.731801 Tz (Gin ) Tj 1.713793 0 Td 65.708812 Tz (Met ) Tj 1.689655 0 Td 68.390805 Tz (Gln ) Tj 28.571429 0 0 28.571429 0 946 Tm 18.69 0 Td 89.444444 Tz (100 ) Tj 30 0 0 30 0 946 Tm 29.466667 0 Td 87.037037 Tz (105 ) Tj 30 0 0 30 0 945 Tm 41.1 0 Td 88.888889 Tz (110 ) Tj 44.285714 0 0 44.285714 0 875.076155 Tm 7.316129 0 Td 62.724014 Tz (Leu ) Tj 1.580645 0 Td 61.469534 Tz (Pro ) Tj 1.580645 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 61.469534 Tz (Tyr ) Tj 1.558065 0 Td 62.724014 Tz (Leu ) Tj 1.535484 0 Td 63.978495 Tz (Ala ) Tj 1.625806 0 Td 61.469534 Tz (Phe ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.580645 0 Td 63.978495 Tz (Asn ) Tj 1.580645 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 62.724014 Tz (Phe ) Tj 1.603226 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 28.571429 0 0 28.571429 0 848 Tm 16.24 0 Td 91.388889 Tz (115 ) Tj 32.857143 0 0 32.857143 0 845 Tm 24.743478 0 Td 79.468599 Tz (120 ) Tj 32.857143 0 0 32.857143 0 845 Tm 35.365217 0 Td 79.468599 Tz (125 ) Tj 44.285714 0 0 44.285714 0 774.934755 Tm 7.270968 0 Td 63.978495 Tz (Ala ) Tj 1.625806 0 Td 60.215054 Tz (Lys ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.512903 0 Td 62.724014 Tz (Val ) Tj 1.580645 0 Td 63.978495 Tz (Glu ) Tj 1.580645 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 61.469534 Tz (Tyr ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 62.724014 Tz (Glu ) Tj 1.580645 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 61.469534 Tz (Lys ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.580645 0 Td 63.978495 Tz (Asp ) Tj 31.428571 0 0 31.428571 0 745 Tm 12.568182 0 Td 83.080808 Tz (130 ) Tj 30 0 0 30 0 747 Tm 24.766667 0 Td 87.037037 Tz (135 ) Tj 32.857143 0 0 32.857143 0 745 Tm 33.265217 0 Td 79.468599 Tz (140 ) Tj 42.857143 0 0 42.857143 0 671.909434 Tm 7.583333 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.656667 0 Td 63.518519 Tz (Thr ) Tj 1.656667 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 62.222222 Tz (Phe ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Lys ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 32.857143 0 0 32.857143 0 642 Tm 9.891304 0 Td 79.468599 Tz (145 ) Tj 31.428571 0 0 31.428571 0 643 Tm 21.413636 0 Td 83.080808 Tz (150 ) Tj 30 0 0 30 0 643 Tm 34.066667 0 Td 87.037037 Tz (155 ) Tj 34.285714 0 0 34.285714 0 641 Tm 40.075 0 Td 74.537037 Tz (160 ) Tj 47.142857 0 0 47.142857 0 565.090566 Tm 6.830303 0 Td 58.922559 Tz (Val ) Tj 1.484848 0 Td 58.922559 Tz (Val ) Tj 1.484848 0 Td 60.10101 Tz (Arg ) Tj 1.548485 0 Td 56.565657 Tz (Ile ) Tj 1.442424 0 Td 56.565657 Tz (Lys ) Tj 1.484848 0 Td 57.744108 Tz (Ser ) Tj 1.442424 0 Td 61.279461 Tz (Asn ) Tj 1.527273 0 Td 57.744108 Tz (Tyr ) Tj 1.484848 0 Td 57.744108 Tz (Phe ) Tj 1.442424 0 Td 60.10101 Tz (Asp ) Tj 1.506061 0 Td 56.565657 Tz (Met ) Tj 1.484848 0 Td 57.744108 Tz (Phe ) Tj 1.484848 0 Td 57.744108 Tz (Trp ) Tj 1.442424 0 Td 61.279461 Tz (Arg ) Tj 1.506061 0 Td 60.10101 Tz (Arg ) Tj 1.527273 0 Td 57.744108 Tz (Ser ) Tj 30 0 0 30 0 538 Tm 20.1 0 Td 87.037037 Tz (165 ) Tj 35.714286 0 0 35.714286 0 535 Tm 26.684 0 Td 71.555556 Tz (170 ) Tj 32.857143 0 0 32.857143 0 536 Tm 39.686957 0 Td 79.468599 Tz (175 ) Tj 42.857143 0 0 42.857143 0 459.8825 Tm 7.56 0 Td 63.518519 Tz (Pro ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Trp ) Tj 1.656667 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 63.518519 Tz (Trp ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.68 0 Td 62.222222 Tz (Thr ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.61 0 Td 68.703704 Tz (Asn ) Tj 1.656667 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 31.428571 0 0 31.428571 0 429 Tm 17.022727 0 Td 81.313131 Tz (180 ) Tj 31.428571 0 0 31.428571 0 430 Tm 28.127273 0 Td 83.080808 Tz (185 ) Tj 30 0 0 30 0 430 Tm 41.1 0 Td 88.888889 Tz (190 ) Tj 41.428571 0 0 41.428571 0 353.89434 Tm 7.772414 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 65.708812 Tz (Phe ) Tj 1.665517 0 Td 64.367816 Tz (Lys ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.665517 0 Td 68.390805 Tz (Gly ) Tj 1.713793 0 Td 65.708812 Tz (Pro ) Tj 1.641379 0 Td 67.049808 Tz (Asp ) Tj 1.713793 0 Td 65.708812 Tz (Phe ) Tj 1.713793 0 Td 64.367816 Tz (Ile ) Tj 1.617241 0 Td 69.731801 Tz (Ala ) Tj 1.762069 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Arg ) Tj 31.428571 0 0 31.428571 0 325 Tm 14.795455 0 Td 83.080808 Tz (195 ) Tj 31.428571 0 0 31.428571 0 325 Tm 25.836364 0 Td 84.848485 Tz (200 ) Tj 32.857143 0 0 32.857143 0 324 Tm 35.365217 0 Td 81.15942 Tz (205 ) Tj 44.285714 0 0 44.285714 0 248.589041 Tm 7.270968 0 Td 65.232975 Tz (Asn ) Tj 1.625806 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 65.232975 Tz (Asn ) Tj 1.558065 0 Td 65.232975 Tz (Asn ) Tj 1.580645 0 Td 65.232975 Tz (Asn ) Tj 1.625806 0 Td 61.469534 Tz (Phe ) Tj 1.580645 0 Td 60.215054 Tz (Cys ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 61.469534 Tz (Leu ) Tj 1.558065 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.558065 0 Td 65.232975 Tz (Glu ) Tj 1.603226 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 60.215054 Tz (Lys ) Tj 30 0 0 30 0 219 Tm 13.1 0 Td 90.740741 Tz (210 ) Tj 30 0 0 30 0 219 Tm 24.766667 0 Td 88.888889 Tz (215 ) Tj 30 0 0 30 0 219 Tm 36.366667 0 Td 88.888889 Tz (220 ) Tj ET Q endstream endobj 215 0 obj << /Length 1 >> stream q endstream endobj 216 0 obj << /Length 20954 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 54.285714 0 0 54.285714 0 2968 Tm 13.742105 0 Td 73.684211 Tz (47 ) Tj 52.857143 0 0 52.857143 0 2973 Tm 32.521622 0 Td 75.675676 Tz (48 ) Tj 47.857143 0 0 47.857143 0 2908.056604 Tm 23.632836 0 Td 41.791045 Tz (- ) Tj 0.41791 0 Td 77.390824 Tz (continued ) Tj 45.714286 0 0 45.714286 0 2804.163955 Tm 7.0875 0 Td 59.548611 Tz (Tyr ) Tj 1.4875 0 Td 61.979167 Tz (Asp ) Tj 1.575 0 Td 58.333333 Tz (Cys ) Tj 1.53125 0 Td 60.763889 Tz (Leu ) Tj 1.465625 0 Td 63.194444 Tz (Asn ) Tj 1.53125 0 Td 61.979167 Tz (Ala ) Tj 1.53125 0 Td 61.979167 Tz (Ala ) Tj 1.53125 0 Td 60.763889 Tz (Val ) Tj 1.553125 0 Td 61.979167 Tz (Gly ) Tj 1.553125 0 Td 59.548611 Tz (Ser ) Tj 1.553125 0 Td 57.118056 Tz (Ile ) Tj 1.4875 0 Td 59.548611 Tz (Thr ) Tj 1.4875 0 Td 61.979167 Tz (Ala ) Tj 1.553125 0 Td 63.194444 Tz (Glu ) Tj 1.53125 0 Td 60.763889 Tz (Val ) Tj 1.575 0 Td 58.333333 Tz (Lys ) Tj 28.571429 0 0 28.571429 0 2778 Tm 11.305 0 Td 93.333333 Tz (225 ) Tj 28.571429 0 0 28.571429 0 2778 Tm 23.52 0 Td 93.333333 Tz (230 ) Tj 28.571429 0 0 28.571429 0 2777 Tm 35.77 0 Td 93.333333 Tz (235 ) Tj 31.428571 0 0 31.428571 0 2776 Tm 43.654545 0 Td 83.080808 Tz (240 ) Tj 42.857143 0 0 42.857143 0 2704.65995 Tm 7.536667 0 Td 63.518519 Tz (Met ) Tj 1.61 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 62.222222 Tz (Cys ) Tj 1.656667 0 Td 62.222222 Tz (Ile ) Tj 1.563333 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 63.518519 Tz (Pro ) Tj 1.656667 0 Td 62.222222 Tz (Ile ) Tj 1.563333 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 66.111111 Tz (Arg ) Tj 1.633333 0 Td 64.814815 Tz (Asp ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 67.407407 Tz (Asp ) Tj 1.656667 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 31.428571 0 0 31.428571 0 2676 Tm 19.186364 0 Td 84.848485 Tz (245 ) Tj 34.285714 0 0 34.285714 0 2676 Tm 27.795833 0 Td 76.157407 Tz (250 ) Tj 34.285714 0 0 34.285714 0 2676 Tm 37.975 0 Td 77.777778 Tz (255 ) Tj 42.857143 0 0 42.857143 0 2604.2575 Tm 7.56 0 Td 63.518519 Tz (Phe ) Tj 1.586667 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Ala ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.656667 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 66.111111 Tz (Asn ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 67.407407 Tz (Glu ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 28.571429 0 0 28.571429 0 2577 Tm 18.69 0 Td 91.388889 Tz (260 ) Tj 31.428571 0 0 31.428571 0 2576 Tm 28.063636 0 Td 84.848485 Tz (265 ) Tj 30 0 0 30 0 2576 Tm 41.066667 0 Td 90.740741 Tz (270 ) Tj 41.428571 0 0 41.428571 0 2505.118388 Tm 7.772414 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 65.708812 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Gln ) Tj 1.737931 0 Td 64.367816 Tz (Ile ) Tj 1.593103 0 Td 67.049808 Tz (Val ) Tj 1.713793 0 Td 68.390805 Tz (Glu ) Tj 1.665517 0 Td 69.731801 Tz (Asn ) Tj 1.713793 0 Td 65.708812 Tz (Met ) Tj 1.713793 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 64.367816 Tz (Thr ) Tj 1.665517 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 65.708812 Tz (Lys ) Tj 1.713793 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 64.367816 Tz (Lys ) Tj 30 0 0 30 0 2476 Tm 15.466667 0 Td 88.888889 Tz (275 ) Tj 30 0 0 30 0 2478 Tm 27.066667 0 Td 88.888889 Tz (280 ) Tj 35.714286 0 0 35.714286 0 2475 Tm 32.536 0 Td 74.666667 Tz (285 ) Tj 40 0 0 40 0 2404.745247 Tm 8.075 0 Td 68.055556 Tz (Met ) Tj 1.8 0 Td 66.666667 Tz (Ile ) Tj 1.725 0 Td 68.055556 Tz (Phe ) Tj 1.75 0 Td 68.055556 Tz (Thr ) Tj 1.725 0 Td 68.055556 Tz (Tyr ) Tj 1.75 0 Td 68.055556 Tz (Thr ) Tj 1.7 0 Td 72.222222 Tz (Asn ) Tj 1.8 0 Td 68.055556 Tz (Thr ) Tj 1.7 0 Td 69.444444 Tz (Val ) Tj 1.775 0 Td 70.833333 Tz (Gin ) Tj 1.775 0 Td 66.666667 Tz (Ser ) Tj 1.725 0 Td 68.055556 Tz (Thr ) Tj 1.75 0 Td 68.055556 Tz (Trp ) Tj 1.75 0 Td 69.444444 Tz (Ser ) Tj 1.775 0 Td 68.055556 Tz (Ser ) Tj 1.75 0 Td 68.055556 Tz (Thr ) Tj 32.857143 0 0 32.857143 0 2376 Tm 11.991304 0 Td 81.15942 Tz (290 ) Tj 31.428571 0 0 31.428571 0 2377 Tm 23.640909 0 Td 84.848485 Tz (295 ) Tj 32.857143 0 0 32.857143 0 2377 Tm 33.204348 0 Td 81.15942 Tz (300 ) Tj 42.857143 0 0 42.857143 0 2305.254777 Tm 7.513333 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 62.222222 Tz (Phe ) Tj 1.61 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 67.407407 Tz (Gly ) Tj 1.703333 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Pro ) Tj 31.428571 0 0 31.428571 0 2277 Tm 10.277273 0 Td 84.848485 Tz (305 ) Tj 30 0 0 30 0 2278 Tm 22.4 0 Td 88.888889 Tz (310 ) Tj 31.428571 0 0 31.428571 0 2277 Tm 32.486364 0 Td 84.848485 Tz (315 ) Tj 31.428571 0 0 31.428571 0 2277 Tm 43.654545 0 Td 83.080808 Tz (320 ) Tj 42.857143 0 0 42.857143 0 2205.1475 Tm 7.56 0 Td 63.518519 Tz (Phe ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Thr ) Tj 1.586667 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 64.814815 Tz (Ser ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 30 0 0 30 0 2178 Tm 20.1 0 Td 88.888889 Tz (325 ) Tj 31.428571 0 0 31.428571 0 2177 Tm 30.322727 0 Td 83.080808 Tz (330 ) Tj 31.428571 0 0 31.428571 0 2178 Tm 41.427273 0 Td 84.848485 Tz (335 ) Tj 44.285714 0 0 44.285714 0 2107.477932 Tm 7.316129 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 61.469534 Tz (Trp ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 63.978495 Tz (Ala ) Tj 1.625806 0 Td 60.215054 Tz (Lys ) Tj 1.580645 0 Td 61.469534 Tz (Ser ) Tj 1.535484 0 Td 63.978495 Tz (Asp ) Tj 1.625806 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 58.960573 Tz (Lys ) Tj 1.512903 0 Td 62.724014 Tz (Val ) Tj 1.580645 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 62.724014 Tz (Ser ) Tj 1.603226 0 Td 60.215054 Tz (Lys ) Tj 1.558065 0 Td 63.978495 Tz (Gln ) Tj 32.857143 0 0 32.857143 0 2076 Tm 16.252174 0 Td 79.468599 Tz (340 ) Tj 30 0 0 30 0 2077 Tm 29.433333 0 Td 88.888889 Tz (345 ) Tj 32.857143 0 0 32.857143 0 2077 Tm 37.495652 0 Td 82.850242 Tz (350 ) Tj 44.285714 0 0 44.285714 0 2004.73891 Tm 7.33871 0 Td 60.215054 Tz (Ile ) Tj 1.512903 0 Td 63.978495 Tz (Asp ) Tj 1.580645 0 Td 62.724014 Tz (Val ) Tj 1.603226 0 Td 63.978495 Tz (Glu ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 61.469534 Tz (Pro ) Tj 1.580645 0 Td 61.469534 Tz (Pro ) Tj 1.558065 0 Td 61.469534 Tz (Met ) Tj 1.603226 0 Td 60.215054 Tz (Lys ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.535484 0 Td 61.469534 Tz (Val ) Tj 1.603226 0 Td 61.469534 Tz (Thr ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 61.469534 Tz (Lys ) Tj 1.558065 0 Td 63.978495 Tz (Ala ) Tj 1.648387 0 Td 60.215054 Tz (Ile ) Tj 31.428571 0 0 31.428571 0 1977 Tm 14.763636 0 Td 84.848485 Tz (355 ) Tj 32.857143 0 0 32.857143 0 1977 Tm 24.743478 0 Td 81.15942 Tz (360 ) Tj 32.857143 0 0 32.857143 0 1976 Tm 35.365217 0 Td 81.15942 Tz (365 ) Tj 42.857143 0 0 42.857143 0 1907.011292 Tm 7.536667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.703333 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Pro ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 62.222222 Tz (Ser ) Tj 1.61 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 67.407407 Tz (Gin ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.633333 0 Td 66.111111 Tz (Asp ) Tj 34.285714 0 0 34.285714 0 1877 Tm 11.491667 0 Td 77.777778 Tz (370 ) Tj 32.857143 0 0 32.857143 0 1878 Tm 22.582609 0 Td 81.15942 Tz (375 ) Tj 31.428571 0 0 31.428571 0 1878 Tm 34.745455 0 Td 84.848485 Tz (380 ) Tj 42.857143 0 0 42.857143 0 1806.535581 Tm 7.583333 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.703333 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 66.111111 Tz (Gin ) Tj 1.633333 0 Td 64.814815 Tz (Glu ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 67.407407 Tz (Asp ) Tj 1.68 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 63.518519 Tz (Met ) Tj 30 0 0 30 0 1778 Tm 10.8 0 Td 88.888889 Tz (385 ) Tj 31.428571 0 0 31.428571 0 1779 Tm 21.381818 0 Td 84.848485 Tz (390 ) Tj 32.857143 0 0 32.857143 0 1778 Tm 31.073913 0 Td 84.541063 Tz (395 ) Tj 32.857143 0 0 32.857143 0 1778 Tm 41.786957 0 Td 79.468599 Tz (400 ) Tj 44.285714 0 0 44.285714 0 1706.75 Tm 7.316129 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 61.469534 Tz (Phe ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 62.724014 Tz (Val ) Tj 1.603226 0 Td 60.215054 Tz (Lys ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 61.469534 Tz (Ser ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.558065 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 60.215054 Tz (Phe ) Tj 1.535484 0 Td 61.469534 Tz (His ) Tj 1.603226 0 Td 61.469534 Tz (Thr ) Tj 1.580645 0 Td 61.469534 Tz (Lys ) Tj 1.580645 0 Td 63.978495 Tz (Glu ) Tj 1.580645 0 Td 63.978495 Tz (Glu ) Tj 30 0 0 30 0 1678 Tm 20.1 0 Td 88.888889 Tz (405 ) Tj 32.857143 0 0 32.857143 0 1678 Tm 29.004348 0 Td 79.468599 Tz (410 ) Tj 30 0 0 30 0 1679 Tm 43.433333 0 Td 88.888889 Tz (415 ) Tj 33.571429 0 0 33.571429 0 1610.494949 Tm 9.621277 0 Td 81.08747 Tz (His ) Tj 2.114894 0 Td 82.742317 Tz (Leu ) Tj 38.571429 0 0 38.571429 0 1506 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (210 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 72.016461 Tz (SEQ ) Tj 1.840741 0 Td 64.814815 Tz (ID ) Tj 1.27037 0 Td 73.45679 Tz (NO ) Tj 1.4 0 Td 64.814815 Tz (26 ) Tj 32.857143 0 0 32.857143 0 1477 Tm 9.86087 0 Td 60.869565 Tz (< ) Tj 0.547826 0 Td 79.468599 Tz (211 ) Tj 1.643478 0 Td 60.869565 Tz (> ) Tj 1.004348 0 Td 86.231884 Tz (LENGTH ) Tj 3.347826 0 Td 20.289855 Tz (: ) Tj 0.913043 0 Td 79.468599 Tz (300 ) Tj 31.428571 0 0 31.428571 0 1444 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 81.313131 Tz (212 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 87.5 Tz (TYPE ) Tj 2.386364 0 Td 21.212121 Tz (: ) Tj 0.954545 0 Td 86.616162 Tz (PRT ) Tj 46.938776 0 0 46.938776 0 1407.118217 Tm 6.902609 0 Td 42.608696 Tz (< ) Tj 0.383478 0 Td 54.444444 Tz (213 ) Tj 1.150435 0 Td 42.608696 Tz (> ) Tj 0.681739 0 Td 58.586957 Tz (ORGANISM ) Tj 3.08913 0 Td 17.753623 Tz (: ) Tj 0.596522 0 Td 61.427536 Tz (Artificial ) Tj 4.154348 0 Td 60.362319 Tz (Sequence ) Tj 31.714286 0 0 31.714286 0 1377.365979 Tm 10.216216 0 Td 63.063063 Tz (< ) Tj 0.567568 0 Td 82.332332 Tz (220 ) Tj 1.702703 0 Td 63.063063 Tz (> ) Tj 1.040541 0 Td 89.339339 Tz (FEATURE ) Tj 4.004505 0 Td 21.021021 Tz (: ) Tj 47.142857 0 0 47.142857 0 1340.122407 Tm 6.872727 0 Td 42.424242 Tz (< ) Tj 0.381818 0 Td 54.208754 Tz (223 ) Tj 1.145455 0 Td 42.424242 Tz (> ) Tj 0.678788 0 Td 60.808081 Tz (OTHER ) Tj 2.269697 0 Td 59.136823 Tz (INFORMATION ) Tj 4.136364 0 Td 17.676768 Tz (: ) Tj 0.615152 0 Td 61.111111 Tz (protein ) Tj 3.012121 0 Td 60.10101 Tz (sequence ) Tj 3.330303 0 Td 59.217172 Tz (from ) Tj 1.845455 0 Td 61.161616 Tz (chemically ) Tj 4.051515 0 Td 61.616162 Tz (mutated ) Tj 39.52381 0 0 39.52381 0 1308.795322 Tm 10.854217 0 Td 72.213855 Tz (Triticum ) Tj 3.972289 0 Td 72.213855 Tz (aestivum ) Tj 3.946988 0 Td 71.686747 Tz (gene ) Tj 38.571429 0 0 38.571429 0 1240 Tm 8.4 0 Td 51.851852 Tz (< ) Tj 0.466667 0 Td 67.695473 Tz (400 ) Tj 1.4 0 Td 51.851852 Tz (> ) Tj 0.855556 0 Td 73.45679 Tz (SEQUENCE ) Tj 3.759259 0 Td 17.283951 Tz (: ) Tj 0.751852 0 Td 64.814815 Tz (26 ) Tj 42.857143 0 0 42.857143 0 1174.345865 Tm 7.513333 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 63.518519 Tz (His ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 66.111111 Tz (Asn ) Tj 1.61 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 64.814815 Tz (Tyr ) Tj 1.656667 0 Td 63.518519 Tz (Trp ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 27.142857 0 0 27.142857 0 1146 Tm 11.973684 0 Td 73.684211 Tz (1 ) Tj 27.142857 0 0 27.142857 0 1146 Tm 22.252632 0 Td 73.684211 Tz (5 ) Tj 30 0 0 30 0 1146 Tm 31.766667 0 Td 80.555556 Tz (10 ) Tj 30 0 0 30 0 1146 Tm 43.466667 0 Td 80.555556 Tz (15 ) Tj 44.285714 0 0 44.285714 0 1073.20776 Tm 7.316129 0 Td 61.469534 Tz (Pro ) Tj 1.558065 0 Td 63.978495 Tz (Gin ) Tj 1.580645 0 Td 63.978495 Tz (Gin ) Tj 1.558065 0 Td 63.978495 Tz (Arg ) Tj 1.603226 0 Td 62.724014 Tz (Leu ) Tj 1.580645 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 61.469534 Tz (His ) Tj 1.580645 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 61.469534 Tz (Ser ) Tj 1.535484 0 Td 63.978495 Tz (Ala ) Tj 1.580645 0 Td 62.724014 Tz (Arg ) Tj 1.603226 0 Td 61.469534 Tz (Trp ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.603226 0 Td 61.469534 Tz (Ile ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 61.469534 Tz (Thr ) Tj 30 0 0 30 0 1046 Tm 17.8 0 Td 83.333333 Tz (20 ) Tj 32.857143 0 0 32.857143 0 1045 Tm 26.843478 0 Td 78.623188 Tz (25 ) Tj 34.285714 0 0 34.285714 0 1043 Tm 35.933333 0 Td 75.347222 Tz (30 ) Tj 40 0 0 40 0 974.105263 Tm 8.05 0 Td 70.833333 Tz (Ala ) Tj 1.75 0 Td 72.222222 Tz (Asn ) Tj 1.775 0 Td 70.833333 Tz (Glu ) Tj 1.775 0 Td 69.444444 Tz (Leu ) Tj 1.7 0 Td 70.833333 Tz (Glu ) Tj 1.75 0 Td 70.833333 Tz (Glu ) Tj 1.725 0 Td 70.833333 Tz (Asp ) Tj 1.8 0 Td 69.444444 Tz (Leu ) Tj 1.75 0 Td 68.055556 Tz (Ser ) Tj 1.75 0 Td 66.666667 Tz (Lys ) Tj 1.75 0 Td 66.666667 Tz (Pro ) Tj 1.725 0 Td 68.055556 Tz (Ser ) Tj 1.75 0 Td 66.666667 Tz (Cys ) Tj 1.75 0 Td 69.444444 Tz (Thr ) Tj 1.775 0 Td 69.444444 Tz (Leu ) Tj 1.75 0 Td 68.055556 Tz (Phe ) Tj 28.571429 0 0 28.571429 0 947 Tm 16.205 0 Td 87.5 Tz (35 ) Tj 28.571429 0 0 28.571429 0 947 Tm 28.42 0 Td 87.5 Tz (40 ) Tj 28.571429 0 0 28.571429 0 947 Tm 40.635 0 Td 87.5 Tz (45 ) Tj 42.857143 0 0 42.857143 0 874.277427 Tm 7.56 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Pro ) Tj 1.563333 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 62.222222 Tz (Ser ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.586667 0 Td 67.407407 Tz (Arg ) Tj 1.703333 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 31.428571 0 0 31.428571 0 846 Tm 12.536364 0 Td 76.893939 Tz (50 ) Tj 31.428571 0 0 31.428571 0 847 Tm 23.640909 0 Td 79.545455 Tz (55 ) Tj 31.428571 0 0 31.428571 0 847 Tm 34.745455 0 Td 79.545455 Tz (60 ) Tj 41.428571 0 0 41.428571 0 774.868852 Tm 7.796552 0 Td 65.708812 Tz (His ) Tj 1.713793 0 Td 65.708812 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Gin ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Gly ) Tj 1.713793 0 Td 64.367816 Tz (Lys ) Tj 1.689655 0 Td 65.708812 Tz (Tyr ) Tj 1.641379 0 Td 68.390805 Tz (Ala ) Tj 1.737931 0 Td 64.367816 Tz (Cys ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 65.708812 Tz (Leu ) Tj 1.665517 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 67.049808 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 1.713793 0 Td 65.708812 Tz (Met ) Tj 28.571429 0 0 28.571429 0 749 Tm 11.34 0 Td 87.5 Tz (65 ) Tj 30 0 0 30 0 747 Tm 22.433333 0 Td 83.333333 Tz (70 ) Tj 30 0 0 30 0 747 Tm 34.066667 0 Td 83.333333 Tz (75 ) Tj 28.571429 0 0 28.571429 0 748 Tm 48.055 0 Td 84.583333 Tz (80 ) Tj 42.857143 0 0 42.857143 0 671.889586 Tm 7.56 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.656667 0 Td 63.518519 Tz (Pro ) Tj 1.61 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.563333 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.656667 0 Td 64.814815 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 67.407407 Tz (Asp ) Tj 1.68 0 Td 66.111111 Tz (Gln ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 28.571429 0 0 28.571429 0 644 Tm 21.105 0 Td 87.5 Tz (85 ) Tj 31.428571 0 0 31.428571 0 643 Tm 30.322727 0 Td 76.893939 Tz (90 ) Tj 30 0 0 30 0 643 Tm 43.433333 0 Td 80.555556 Tz (95 ) Tj 42.857143 0 0 42.857143 0 564.761194 Tm 7.513333 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.61 0 Td 66.111111 Tz (Ala ) Tj 1.68 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.633333 0 Td 63.518519 Tz (Val ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Glu ) Tj 1.633333 0 Td 67.407407 Tz (Gin ) Tj 1.656667 0 Td 63.518519 Tz (Met ) Tj 1.633333 0 Td 66.111111 Tz (Gin ) Tj 35.714286 0 0 35.714286 0 535 Tm 14.952 0 Td 73.111111 Tz (100 ) Tj 31.428571 0 0 31.428571 0 537 Tm 28.095455 0 Td 83.080808 Tz (105 ) Tj 31.428571 0 0 31.428571 0 536 Tm 39.2 0 Td 84.848485 Tz (110 ) Tj 42.857143 0 0 42.857143 0 460.636704 Tm 7.56 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 63.518519 Tz (Pro ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.61 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.68 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.633333 0 Td 66.111111 Tz (Asn ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.61 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 64.814815 Tz (Phe ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 30 0 0 30 0 430 Tm 15.5 0 Td 87.037037 Tz (115 ) Tj 30 0 0 30 0 430 Tm 27.1 0 Td 87.037037 Tz (120 ) Tj 32.857143 0 0 32.857143 0 429 Tm 35.365217 0 Td 79.468599 Tz (125 ) Tj 44.285714 0 0 44.285714 0 354.562821 Tm 7.270968 0 Td 63.978495 Tz (Ala ) Tj 1.625806 0 Td 60.215054 Tz (Lys ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.512903 0 Td 62.724014 Tz (Val ) Tj 1.580645 0 Td 63.978495 Tz (Glu ) Tj 1.580645 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 61.469534 Tz (Tyr ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 62.724014 Tz (Glu ) Tj 1.580645 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 61.469534 Tz (Lys ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.648387 0 Td 63.978495 Tz (As ) Tj 32.857143 0 0 32.857143 0 324 Tm 12.021739 0 Td 79.468599 Tz (130 ) Tj 32.857143 0 0 32.857143 0 324 Tm 22.643478 0 Td 79.468599 Tz (135 ) Tj 30 0 0 30 0 324 Tm 36.433333 0 Td 87.037037 Tz (140 ) Tj 41.428571 0 0 41.428571 0 248.909434 Tm 7.844828 0 Td 64.367816 Tz (Ile ) Tj 1.641379 0 Td 68.390805 Tz (Gly ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.665517 0 Td 65.708812 Tz (Ser ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.665517 0 Td 65.708812 Tz (His ) Tj 1.713793 0 Td 65.708812 Tz (Thr ) Tj 1.713793 0 Td 64.367816 Tz (Ile ) Tj 1.665517 0 Td 64.367816 Tz (Phe ) Tj 1.665517 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 65.708812 Tz (Lys ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 1.713793 0 Td 68.390805 Tz (Gly ) Tj 30 0 0 30 0 220 Tm 10.8 0 Td 87.037037 Tz (145 ) Tj 32.857143 0 0 32.857143 0 218 Tm 20.482609 0 Td 79.468599 Tz (150 ) Tj 30 0 0 30 0 219 Tm 34.1 0 Td 87.037037 Tz (155 ) Tj 28.571429 0 0 28.571429 0 219 Tm 48.09 0 Td 89.444444 Tz (160 ) Tj ET Q endstream endobj 217 0 obj << /Length 1 >> stream q endstream endobj 218 0 obj << /Length 18812 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 62.857143 0 0 62.857143 0 3026 Tm 16.990909 0 Td 82.19697 Tz (US ) Tj 1.4 0 Td 57.272727 Tz (11,072,799 ) Tj 3.754545 0 Td 71.590909 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.486111 0 Td 77.777778 Tz (49 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 33.463889 0 Td 74.537037 Tz (50 ) Tj 47.857143 0 0 47.857143 0 2907.056604 Tm 23.632836 0 Td 41.791045 Tz (- ) Tj 0.41791 0 Td 77.390824 Tz (continued ) Tj 42.857143 0 0 42.857143 0 2800.649057 Tm 7.513333 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.703333 0 Td 62.222222 Tz (Ile ) Tj 1.586667 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 1.586667 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 62.222222 Tz (Met ) Tj 1.633333 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 63.518519 Tz (Trp ) Tj 1.586667 0 Td 67.407407 Tz (Arg ) Tj 1.656667 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 30 0 0 30 0 2769 Tm 20.133333 0 Td 87.037037 Tz (165 ) Tj 30 0 0 30 0 2769 Tm 31.8 0 Td 85.185185 Tz (170 ) Tj 31.428571 0 0 31.428571 0 2769 Tm 41.459091 0 Td 83.080808 Tz (175 ) Tj 41.428571 0 0 41.428571 0 2694.8825 Tm 7.82069 0 Td 65.708812 Tz (Pro ) Tj 1.641379 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 65.708812 Tz (Trp ) Tj 1.713793 0 Td 64.367816 Tz (Ile ) Tj 1.641379 0 Td 65.708812 Tz (Trp ) Tj 1.641379 0 Td 68.390805 Tz (Ala ) Tj 1.689655 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 64.367816 Tz (Thr ) Tj 1.665517 0 Td 65.708812 Tz (Thr ) Tj 1.665517 0 Td 65.708812 Tz (His ) Tj 1.665517 0 Td 71.072797 Tz (Asn ) Tj 1.713793 0 Td 69.731801 Tz (Asn ) Tj 1.689655 0 Td 68.390805 Tz (Arg ) Tj 28.571429 0 0 28.571429 0 2665 Tm 18.69 0 Td 89.444444 Tz (180 ) Tj 30 0 0 30 0 2663 Tm 29.466667 0 Td 87.037037 Tz (185 ) Tj 31.428571 0 0 31.428571 0 2662 Tm 39.231818 0 Td 84.848485 Tz (190 ) Tj 41.428571 0 0 41.428571 0 2588.89434 Tm 7.772414 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 65.708812 Tz (Phe ) Tj 1.665517 0 Td 64.367816 Tz (Lys ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.665517 0 Td 68.390805 Tz (Gly ) Tj 1.713793 0 Td 65.708812 Tz (Pro ) Tj 1.641379 0 Td 67.049808 Tz (Asp ) Tj 1.713793 0 Td 65.708812 Tz (Phe ) Tj 1.713793 0 Td 64.367816 Tz (Ile ) Tj 1.617241 0 Td 69.731801 Tz (Ala ) Tj 1.762069 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Arg ) Tj 32.857143 0 0 32.857143 0 2557 Tm 14.121739 0 Td 79.468599 Tz (195 ) Tj 30 0 0 30 0 2558 Tm 27.066667 0 Td 88.888889 Tz (200 ) Tj 31.428571 0 0 31.428571 0 2557 Tm 36.972727 0 Td 84.848485 Tz (205 ) Tj 45.714286 0 0 45.714286 0 2481.589041 Tm 7.04375 0 Td 63.194444 Tz (Asn ) Tj 1.575 0 Td 60.763889 Tz (Leu ) Tj 1.509375 0 Td 61.979167 Tz (Gly ) Tj 1.509375 0 Td 63.194444 Tz (Asn ) Tj 1.509375 0 Td 63.194444 Tz (Asn ) Tj 1.53125 0 Td 63.194444 Tz (Asn ) Tj 1.575 0 Td 59.548611 Tz (Phe ) Tj 1.53125 0 Td 58.333333 Tz (Cys ) Tj 1.53125 0 Td 58.333333 Tz (Lys ) Tj 1.4875 0 Td 61.979167 Tz (Arg ) Tj 1.575 0 Td 59.548611 Tz (Leu ) Tj 1.509375 0 Td 59.548611 Tz (Thr ) Tj 1.53125 0 Td 59.548611 Tz (Thr ) Tj 1.509375 0 Td 63.194444 Tz (Glu ) Tj 1.553125 0 Td 61.979167 Tz (Gly ) Tj 1.553125 0 Td 58.333333 Tz (Lys ) Tj 30 0 0 30 0 2452 Tm 13.1 0 Td 88.888889 Tz (210 ) Tj 28.571429 0 0 28.571429 0 2453 Tm 25.97 0 Td 93.333333 Tz (215 ) Tj 32.857143 0 0 32.857143 0 2451 Tm 33.173913 0 Td 84.541063 Tz (220 ) Tj 47.142857 0 0 47.142857 0 2375.163955 Tm 6.872727 0 Td 57.744108 Tz (Tyr ) Tj 1.442424 0 Td 60.10101 Tz (Asp ) Tj 1.527273 0 Td 56.565657 Tz (Cys ) Tj 1.484848 0 Td 58.922559 Tz (Leu ) Tj 1.421212 0 Td 61.279461 Tz (Asn ) Tj 1.484848 0 Td 60.10101 Tz (Ala ) Tj 1.484848 0 Td 60.10101 Tz (Ala ) Tj 1.484848 0 Td 58.922559 Tz (Val ) Tj 1.506061 0 Td 60.10101 Tz (Gly ) Tj 1.506061 0 Td 57.744108 Tz (Ser ) Tj 1.506061 0 Td 55.387205 Tz (Ile ) Tj 1.442424 0 Td 57.744108 Tz (Thr ) Tj 1.442424 0 Td 60.10101 Tz (Ala ) Tj 1.506061 0 Td 61.279461 Tz (Glu ) Tj 1.484848 0 Td 58.922559 Tz (Val ) Tj 1.527273 0 Td 56.565657 Tz (Lys ) Tj 32.857143 0 0 32.857143 0 2344 Tm 9.86087 0 Td 81.15942 Tz (225 ) Tj 34.285714 0 0 34.285714 0 2344 Tm 19.570833 0 Td 81.018519 Tz (230 ) Tj 34.285714 0 0 34.285714 0 2344 Tm 29.75 0 Td 81.018519 Tz (235 ) Tj 32.857143 0 0 32.857143 0 2345 Tm 41.756522 0 Td 79.468599 Tz (240 ) Tj 43.571429 0 0 43.571429 0 2273 Tm 7.390164 0 Td 65.027322 Tz (Met ) Tj 1.606557 0 Td 65.027322 Tz (Arg ) Tj 44.285714 0 0 44.285714 0 2271.036023 Tm 10.477419 0 Td 60.215054 Tz (Cys ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.512903 0 Td 63.978495 Tz (Glu ) Tj 1.603226 0 Td 61.469534 Tz (Pro ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.512903 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 61.469534 Tz (Ser ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.580645 0 Td 62.724014 Tz (Asp ) Tj 1.625806 0 Td 60.215054 Tz (Ile ) Tj 1.558065 0 Td 61.469534 Tz (Tyr ) Tj 1.535484 0 Td 65.232975 Tz (Asp ) Tj 1.603226 0 Td 62.724014 Tz (Val ) Tj 1.580645 0 Td 63.978495 Tz (Asp ) Tj 31.428571 0 0 31.428571 0 2238 Tm 19.186364 0 Td 84.848485 Tz (245 ) Tj 31.428571 0 0 31.428571 0 2239 Tm 30.290909 0 Td 83.080808 Tz (250 ) Tj 30 0 0 30 0 2239 Tm 43.433333 0 Td 88.888889 Tz (255 ) Tj 44.285714 0 0 44.285714 0 2159.63375 Tm 7.316129 0 Td 61.469534 Tz (Phe ) Tj 1.535484 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 63.978495 Tz (Glu ) Tj 1.558065 0 Td 63.978495 Tz (Ala ) Tj 1.625806 0 Td 60.215054 Tz (Lys ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.558065 0 Td 61.469534 Tz (Tyr ) Tj 1.580645 0 Td 61.469534 Tz (Thr ) Tj 1.535484 0 Td 63.978495 Tz (Asn ) Tj 1.580645 0 Td 63.978495 Tz (Gly ) Tj 1.625806 0 Td 60.215054 Tz (Ile ) Tj 1.535484 0 Td 65.232975 Tz (Glu ) Tj 1.603226 0 Td 63.978495 Tz (Gly ) Tj 1.603226 0 Td 62.724014 Tz (Leu ) Tj 31.428571 0 0 31.428571 0 2127 Tm 16.990909 0 Td 83.080808 Tz (260 ) Tj 28.571429 0 0 28.571429 0 2128 Tm 30.87 0 Td 93.333333 Tz (265 ) Tj 30 0 0 30 0 2128 Tm 41.066667 0 Td 90.740741 Tz (270 ) Tj 41.428571 0 0 41.428571 0 2046.118388 Tm 7.772414 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 65.708812 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Gin ) Tj 1.737931 0 Td 64.367816 Tz (Ile ) Tj 1.593103 0 Td 67.049808 Tz (Val ) Tj 1.713793 0 Td 68.390805 Tz (Glu ) Tj 1.665517 0 Td 69.731801 Tz (Asn ) Tj 1.713793 0 Td 65.708812 Tz (Met ) Tj 1.713793 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 64.367816 Tz (Thr ) Tj 1.665517 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 65.708812 Tz (Lys ) Tj 1.713793 0 Td 65.708812 Tz (Thr ) Tj 1.689655 0 Td 64.367816 Tz (Lys ) Tj 30 0 0 30 0 2016 Tm 15.433333 0 Td 88.888889 Tz (275 ) Tj 28.571429 0 0 28.571429 0 2016 Tm 28.455 0 Td 93.333333 Tz (280 ) Tj 30 0 0 30 0 2015 Tm 38.733333 0 Td 88.888889 Tz (285 ) Tj 42.857143 0 0 42.857143 0 1934.496622 Tm 7.536667 0 Td 63.518519 Tz (Met ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.61 0 Td 63.518519 Tz (Tyr ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 63.518519 Tz (Thr ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.656667 0 Td 66.111111 Tz (Gin ) Tj 1.656667 0 Td 62.222222 Tz (Ser ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 32.857143 0 0 32.857143 0 1902 Tm 11.96087 0 Td 81.15942 Tz (290 ) Tj 31.428571 0 0 31.428571 0 1903 Tm 23.640909 0 Td 84.848485 Tz (295 ) Tj 32.857143 0 0 32.857143 0 1903 Tm 33.234783 0 Td 81.15942 Tz (300 ) Tj 40 0 0 40 0 1786 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (210 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 69.444444 Tz (SEQ ) Tj 1.775 0 Td 62.5 Tz (ID ) Tj 1.225 0 Td 70.833333 Tz (NO ) Tj 1.35 0 Td 64.583333 Tz (27 ) Tj 31.428571 0 0 31.428571 0 1753 Tm 10.309091 0 Td 63.636364 Tz (< ) Tj 0.572727 0 Td 83.080808 Tz (211 ) Tj 1.718182 0 Td 63.636364 Tz (> ) Tj 1.05 0 Td 90.151515 Tz (LENGTH ) Tj 3.5 0 Td 21.212121 Tz (: ) Tj 0.986364 0 Td 79.545455 Tz (172 ) Tj 34.285714 0 0 34.285714 0 1715 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 74.537037 Tz (212 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 80.208333 Tz (TYPE ) Tj 2.1875 0 Td 19.444444 Tz (: ) Tj 0.875 0 Td 79.398148 Tz (PRT ) Tj 41.22449 0 0 41.22449 0 1674.598837 Tm 7.859406 0 Td 48.514851 Tz (< ) Tj 0.436634 0 Td 61.991199 Tz (213 ) Tj 1.309901 0 Td 48.514851 Tz (> ) Tj 0.776238 0 Td 66.707921 Tz (ORGANISM ) Tj 3.517327 0 Td 20.214521 Tz (: ) Tj 0.679208 0 Td 69.942244 Tz (Artificial ) Tj 4.730198 0 Td 68.729373 Tz (Sequence ) Tj 34.285714 0 0 34.285714 0 1639 Tm 9.45 0 Td 58.333333 Tz (< ) Tj 0.525 0 Td 76.157407 Tz (220 ) Tj 1.575 0 Td 58.333333 Tz (> ) Tj 0.9625 0 Td 82.638889 Tz (FEATURE ) Tj 3.704167 0 Td 19.444444 Tz (: ) Tj 50 0 0 50 0 1596.11272 Tm 6.48 0 Td 40 Tz (< ) Tj 0.36 0 Td 51.111111 Tz (223 ) Tj 1.08 0 Td 40 Tz (> ) Tj 0.64 0 Td 57.333333 Tz (OTHER ) Tj 2.14 0 Td 56.666667 Tz (INFORMATION ) Tj 3.92 0 Td 16.666667 Tz (: ) Tj 0.56 0 Td 57.619048 Tz (protein ) Tj 2.84 0 Td 56.666667 Tz (sequence ) Tj 3.14 0 Td 55.833333 Tz (from ) Tj 1.74 0 Td 57.666667 Tz (chemically ) Tj 3.82 0 Td 58.095238 Tz (mutated ) Tj 41.904762 0 0 41.904762 0 1562.596491 Tm 10.2375 0 Td 68.110795 Tz (Triticum ) Tj 3.746591 0 Td 68.110795 Tz (aestivum ) Tj 3.722727 0 Td 67.613636 Tz (gene ) Tj 40 0 0 40 0 1486 Tm 8.1 0 Td 50 Tz (< ) Tj 0.45 0 Td 65.277778 Tz (400 ) Tj 1.35 0 Td 50 Tz (> ) Tj 0.825 0 Td 70.833333 Tz (SEQUENCE ) Tj 3.625 0 Td 16.666667 Tz (: ) Tj 0.725 0 Td 64.583333 Tz (27 ) Tj 42.857143 0 0 42.857143 0 1411.345865 Tm 7.513333 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.586667 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 63.518519 Tz (His ) Tj 1.61 0 Td 64.814815 Tz (Val ) Tj 1.633333 0 Td 66.111111 Tz (Arg ) Tj 1.68 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.633333 0 Td 63.518519 Tz (Tyr ) Tj 1.586667 0 Td 66.111111 Tz (Asn ) Tj 1.61 0 Td 67.407407 Tz (Asn ) Tj 1.68 0 Td 62.222222 Tz (Lys ) Tj 1.633333 0 Td 64.814815 Tz (Tyr ) Tj 1.656667 0 Td 63.518519 Tz (Trp ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 30 0 0 30 0 1378 Tm 10.833333 0 Td 66.666667 Tz (1 ) Tj 28.571429 0 0 28.571429 0 1380 Tm 21.105 0 Td 70 Tz (5 ) Tj 30 0 0 30 0 1379 Tm 31.766667 0 Td 80.555556 Tz (10 ) Tj 30 0 0 30 0 1379 Tm 43.433333 0 Td 80.555556 Tz (15 ) Tj 42.857143 0 0 42.857143 0 1297.892365 Tm 7.56 0 Td 63.518519 Tz (Pro ) Tj 1.61 0 Td 66.111111 Tz (Gin ) Tj 1.633333 0 Td 66.111111 Tz (Gin ) Tj 1.61 0 Td 66.111111 Tz (Arg ) Tj 1.656667 0 Td 64.814815 Tz (Leu ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.633333 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 63.518519 Tz (Ser ) Tj 1.586667 0 Td 66.111111 Tz (Ala ) Tj 1.633333 0 Td 64.814815 Tz (Arg ) Tj 1.656667 0 Td 63.518519 Tz (Trp ) Tj 1.633333 0 Td 63.518519 Tz (Thr ) Tj 1.656667 0 Td 63.518519 Tz (Ile ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 63.518519 Tz (Thr ) Tj 31.428571 0 0 31.428571 0 1265 Tm 16.990909 0 Td 79.545455 Tz (20 ) Tj 30 0 0 30 0 1267 Tm 29.4 0 Td 83.333333 Tz (25 ) Tj 28.571429 0 0 28.571429 0 1268 Tm 43.085 0 Td 87.5 Tz (30 ) Tj 41.428571 0 0 41.428571 0 1185.105263 Tm 7.772414 0 Td 68.390805 Tz (Ala ) Tj 1.689655 0 Td 69.731801 Tz (Asn ) Tj 1.713793 0 Td 68.390805 Tz (Glu ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Glu ) Tj 1.689655 0 Td 68.390805 Tz (Glu ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 64.367816 Tz (Lys ) Tj 1.689655 0 Td 64.367816 Tz (Pro ) Tj 1.665517 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 64.367816 Tz (Cys ) Tj 1.689655 0 Td 67.049808 Tz (Thr ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 65.708812 Tz (Phe ) Tj 27.142857 0 0 27.142857 0 1156 Tm 17.057895 0 Td 92.105263 Tz (35 ) Tj 28.571429 0 0 28.571429 0 1155 Tm 28.42 0 Td 87.5 Tz (40 ) Tj 28.571429 0 0 28.571429 0 1155 Tm 40.635 0 Td 87.5 Tz (45 ) Tj 42.857143 0 0 42.857143 0 1073.277427 Tm 7.56 0 Td 62.222222 Tz (Lys ) Tj 1.61 0 Td 63.518519 Tz (His ) Tj 1.68 0 Td 62.222222 Tz (Ile ) Tj 1.61 0 Td 63.518519 Tz (Pro ) Tj 1.563333 0 Td 64.814815 Tz (Val ) Tj 1.68 0 Td 63.518519 Tz (Ser ) Tj 1.61 0 Td 66.111111 Tz (Gly ) Tj 1.633333 0 Td 66.111111 Tz (Glu ) Tj 1.61 0 Td 66.111111 Tz (Asp ) Tj 1.656667 0 Td 66.111111 Tz (Gly ) Tj 1.656667 0 Td 62.222222 Tz (Ser ) Tj 1.61 0 Td 63.518519 Tz (Thr ) Tj 1.633333 0 Td 62.222222 Tz (Cys ) Tj 1.586667 0 Td 67.407407 Tz (Arg ) Tj 1.703333 0 Td 63.518519 Tz (Phe ) Tj 1.633333 0 Td 64.814815 Tz (Leu ) Tj 28.571429 0 0 28.571429 0 1043 Tm 13.79 0 Td 84.583333 Tz (50 ) Tj 28.571429 0 0 28.571429 0 1044 Tm 26.005 0 Td 87.5 Tz (55 ) Tj 27.142857 0 0 27.142857 0 1043 Tm 40.231579 0 Td 92.105263 Tz (60 ) Tj 41.428571 0 0 41.428571 0 961.868852 Tm 7.796552 0 Td 65.708812 Tz (His ) Tj 1.713793 0 Td 65.708812 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Gin ) Tj 1.713793 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Gly ) Tj 1.713793 0 Td 64.367816 Tz (Lys ) Tj 1.689655 0 Td 65.708812 Tz (Tyr ) Tj 1.641379 0 Td 68.390805 Tz (Ala ) Tj 1.737931 0 Td 64.367816 Tz (Cys ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 65.708812 Tz (Leu ) Tj 1.665517 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 67.049808 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 1.713793 0 Td 65.708812 Tz (Met ) Tj 28.571429 0 0 28.571429 0 931 Tm 11.34 0 Td 87.5 Tz (65 ) Tj 28.571429 0 0 28.571429 0 931 Tm 23.555 0 Td 87.5 Tz (70 ) Tj 27.142857 0 0 27.142857 0 931 Tm 37.652632 0 Td 92.105263 Tz (75 ) Tj 28.571429 0 0 28.571429 0 931 Tm 48.055 0 Td 84.583333 Tz (80 ) Tj 41.428571 0 0 41.428571 0 849.889586 Tm 7.82069 0 Td 65.708812 Tz (Ser ) Tj 1.689655 0 Td 64.367816 Tz (Lys ) Tj 1.665517 0 Td 65.708812 Tz (His ) Tj 1.713793 0 Td 65.708812 Tz (Pro ) Tj 1.665517 0 Td 65.708812 Tz (Tyr ) Tj 1.689655 0 Td 67.049808 Tz (Leu ) Tj 1.665517 0 Td 65.708812 Tz (His ) Tj 1.737931 0 Td 64.367816 Tz (Ile ) Tj 1.617241 0 Td 68.390805 Tz (Ala ) Tj 1.689655 0 Td 68.390805 Tz (Arg ) Tj 1.713793 0 Td 67.049808 Tz (Glu ) Tj 1.665517 0 Td 68.390805 Tz (Glu ) Tj 1.713793 0 Td 65.708812 Tz (Ser ) Tj 1.641379 0 Td 69.731801 Tz (Asp ) Tj 1.737931 0 Td 68.390805 Tz (Gin ) Tj 1.665517 0 Td 68.390805 Tz (Asp ) Tj 28.571429 0 0 28.571429 0 819 Tm 21.105 0 Td 87.5 Tz (85 ) Tj 28.571429 0 0 28.571429 0 819 Tm 33.355 0 Td 84.583333 Tz (90 ) Tj 28.571429 0 0 28.571429 0 819 Tm 45.605 0 Td 84.583333 Tz (95 ) Tj 41.428571 0 0 41.428571 0 736.761194 Tm 7.772414 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.689655 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.665517 0 Td 68.390805 Tz (Ala ) Tj 1.737931 0 Td 65.708812 Tz (Phe ) Tj 1.689655 0 Td 65.708812 Tz (Thr ) Tj 1.641379 0 Td 67.049808 Tz (Val ) Tj 1.737931 0 Td 67.049808 Tz (Leu ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.689655 0 Td 65.708812 Tz (Val ) Tj 1.713793 0 Td 65.708812 Tz (Ser ) Tj 1.665517 0 Td 68.390805 Tz (Glu ) Tj 1.689655 0 Td 69.731801 Tz (Gin ) Tj 1.713793 0 Td 65.708812 Tz (Met ) Tj 1.689655 0 Td 68.390805 Tz (Gln ) Tj 34.285714 0 0 34.285714 0 704 Tm 15.575 0 Td 74.537037 Tz (100 ) Tj 31.428571 0 0 31.428571 0 704 Tm 28.127273 0 Td 83.080808 Tz (105 ) Tj 30 0 0 30 0 705 Tm 41.1 0 Td 88.888889 Tz (110 ) Tj 44.285714 0 0 44.285714 0 625.076155 Tm 7.316129 0 Td 62.724014 Tz (Leu ) Tj 1.580645 0 Td 61.469534 Tz (Pro ) Tj 1.580645 0 Td 61.469534 Tz (Ser ) Tj 1.580645 0 Td 61.469534 Tz (Tyr ) Tj 1.558065 0 Td 62.724014 Tz (Leu ) Tj 1.535484 0 Td 63.978495 Tz (Ala ) Tj 1.625806 0 Td 61.469534 Tz (Phe ) Tj 1.580645 0 Td 60.215054 Tz (Lys ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.580645 0 Td 63.978495 Tz (Asn ) Tj 1.580645 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 63.978495 Tz (Arg ) Tj 1.625806 0 Td 62.724014 Tz (Phe ) Tj 1.603226 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 63.978495 Tz (Gly ) Tj 30 0 0 30 0 593 Tm 15.5 0 Td 87.037037 Tz (115 ) Tj 31.428571 0 0 31.428571 0 593 Tm 25.9 0 Td 83.080808 Tz (120 ) Tj 30 0 0 30 0 593 Tm 38.766667 0 Td 87.037037 Tz (125 ) Tj 47.142857 0 0 47.142857 0 511.934755 Tm 6.830303 0 Td 60.10101 Tz (Ala ) Tj 1.527273 0 Td 56.565657 Tz (Lys ) Tj 1.506061 0 Td 56.565657 Tz (Ile ) Tj 1.421212 0 Td 58.922559 Tz (Val ) Tj 1.484848 0 Td 60.10101 Tz (Glu ) Tj 1.484848 0 Td 60.10101 Tz (Gly ) Tj 1.506061 0 Td 57.744108 Tz (Tyr ) Tj 1.442424 0 Td 60.10101 Tz (Arg ) Tj 1.527273 0 Td 57.744108 Tz (Tyr ) Tj 1.484848 0 Td 58.922559 Tz (Leu ) Tj 1.463636 0 Td 58.922559 Tz (Glu ) Tj 1.484848 0 Td 57.744108 Tz (Tyr ) Tj 1.484848 0 Td 57.744108 Tz (Ser ) Tj 1.484848 0 Td 57.744108 Tz (Lys ) Tj 1.463636 0 Td 60.10101 Tz (Asp ) Tj 1.484848 0 Td 60.10101 Tz (Asp ) Tj 34.285714 0 0 34.285714 0 479 Tm 11.491667 0 Td 77.777778 Tz (130 ) Tj 32.857143 0 0 32.857143 0 480 Tm 22.643478 0 Td 79.468599 Tz (135 ) Tj 31.428571 0 0 31.428571 0 480 Tm 34.777273 0 Td 83.080808 Tz (140 ) Tj 44.285714 0 0 44.285714 0 399.227673 Tm 7.33871 0 Td 60.215054 Tz (Ile ) Tj 1.535484 0 Td 63.978495 Tz (Gly ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.625806 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 61.469534 Tz (Ser ) Tj 1.535484 0 Td 62.724014 Tz (Val ) Tj 1.625806 0 Td 62.724014 Tz (Leu ) Tj 1.558065 0 Td 61.469534 Tz (His ) Tj 1.603226 0 Td 61.469534 Tz (Thr ) Tj 1.603226 0 Td 60.215054 Tz (Ile ) Tj 1.558065 0 Td 60.215054 Tz (Phe ) Tj 1.558065 0 Td 61.469534 Tz (Thr ) Tj 1.535484 0 Td 65.232975 Tz (Asn ) Tj 1.625806 0 Td 61.469534 Tz (Lys ) Tj 1.558065 0 Td 63.978495 Tz (Asp ) Tj 1.603226 0 Td 63.978495 Tz (Gly ) Tj 31.428571 0 0 31.428571 0 367 Tm 10.340909 0 Td 83.080808 Tz (145 ) Tj 31.428571 0 0 31.428571 0 369 Tm 21.445455 0 Td 83.080808 Tz (150 ) Tj 30 0 0 30 0 370 Tm 34.066667 0 Td 87.037037 Tz (155 ) Tj 35.714286 0 0 35.714286 0 367 Tm 38.472 0 Td 71.555556 Tz (160 ) Tj 41.428571 0 0 41.428571 0 289.010101 Tm 7.772414 0 Td 67.049808 Tz (Val ) Tj 1.689655 0 Td 67.049808 Tz (Val ) Tj 1.689655 0 Td 68.390805 Tz (Arg ) Tj 1.762069 0 Td 64.367816 Tz (Ile ) Tj 1.641379 0 Td 64.367816 Tz (Lys ) Tj 1.689655 0 Td 65.708812 Tz (Ser ) Tj 1.641379 0 Td 69.731801 Tz (Asn ) Tj 1.737931 0 Td 65.708812 Tz (Tyr ) Tj 1.689655 0 Td 65.708812 Tz (Phe ) Tj 1.641379 0 Td 68.390805 Tz (Asp ) Tj 1.713793 0 Td 64.367816 Tz (Met ) Tj 1.689655 0 Td 65.708812 Tz (Phe ) Tj 32.857143 0 0 32.857143 0 255 Tm 18.352174 0 Td 79.468599 Tz (165 ) Tj 31.428571 0 0 31.428571 0 256 Tm 30.354545 0 Td 81.313131 Tz (170 ) Tj ET Q endstream endobj 219 0 obj << /Length 1 >> stream q endstream endobj 220 0 obj << /Length 36759 >> stream Q q 0.24 0 0 0.24 0 0 cm BT /F1 1 Tf 3 Tr 31.428571 0 0 31.428571 0 2547 Tm 39.613636 0 Td 66.287879 Tz (10 ) Tj 30 0 0 30 0 2132 Tm 41.433333 0 Td 75 Tz (20 ) Tj 60.952381 0 0 60.952381 0 3027.187879 Tm 17.521875 0 Td 84.765625 Tz (US ) Tj 1.44375 0 Td 59.0625 Tz (11,072,799 ) Tj 3.904687 0 Td 71.09375 Tz (B2 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 14.525 0 Td 64.814815 Tz (51 ) Tj 51.428571 0 0 51.428571 0 2971 Tm 33.463889 0 Td 74.537037 Tz (52 ) Tj 45.714286 0 0 45.714286 0 2919 Tm 7.896875 0 Td 68.055556 Tz (The ) Tj 1.53125 0 Td 57.118056 Tz (invention ) Tj 3.36875 0 Td 61.458333 Tz (claimed ) Tj 2.865625 0 Td 40.104167 Tz (is ) Tj 0.590625 0 Td 14.583333 Tz (: ) Tj 59.464286 0 0 59.464286 0 2915.665746 Tm 21.794595 0 Td 43.910577 Tz (incorporated ) Tj 3.649249 0 Td 38.538539 Tz (into ) Tj 1.429429 0 Td 30.830831 Tz (its ) Tj 1.059459 0 Td 55.588922 Tz (genome ) Tj 1.984384 0 Td 19.61962 Tz (, ) Tj 0.622222 0 Td 48.448448 Tz (wherein ) Tj 2.488889 0 Td 42.042042 Tz (the ) Tj 1.227628 0 Td 43.723724 Tz (nucleotide ) Tj 60.982143 0 0 60.982143 0 2871.041253 Tm 5.936164 0 Td 31.429966 Tz (1. ) Tj 0.606735 0 Td 73.792094 Tz (A ) Tj 0.623133 0 Td 51.472263 Tz (method ) Tj 2.082577 0 Td 39.173581 Tz (for ) Tj 0.9347 0 Td 41.542216 Tz (increasing ) Tj 2.722108 0 Td 40.175695 Tz (resistance ) Tj 2.640117 0 Td 38.262567 Tz (to ) Tj 0.688726 0 Td 49.194729 Tz (Fusarium ) Tj 2.623719 0 Td 48.511469 Tz (head ) Tj 2.410542 0 Td 46.120059 Tz (sequence ) Tj 2.443338 0 Td 46.461689 Tz (of ) Tj 0.721523 0 Td 40.312347 Tz (said ) Tj 1.180673 0 Td 47.980044 Tz (exogenous ) Tj 2.8041 0 Td 42.166911 Tz (nucleic ) Tj 2.000586 0 Td 42.362128 Tz (acid ) Tj 1.049488 0 Td 13.665203 Tz (: ) Tj 59.419643 0 0 59.419643 0 2828.949367 Tm 5.419083 0 Td 40.671175 Tz (blight ) Tj 1.716604 0 Td 28.049086 Tz (\( ) Tj 0.185124 0 Td 65.447867 Tz (FHB ) Tj 1.22855 0 Td 28.049086 Tz (\) ) Tj 0.420736 0 Td 41.138659 Tz (infection ) Tj 2.44027 0 Td 40.671175 Tz (in ) Tj 0.706837 0 Td 42.073629 Tz (a ) Tj 0.471225 0 Td 42.634611 Tz (plant ) Tj 1.22855 0 Td 28.049086 Tz (, ) Tj 0.420736 0 Td 41.372402 Tz (said ) Tj 1.194891 0 Td 52.358294 Tz (method ) Tj 2.120511 0 Td 47.963937 Tz (comprising ) Tj 2.76003 0 Td 28.049086 Tz (: ) Tj 2.15417 0 Td 28.049086 Tz (\( ) Tj 0.201953 0 Td 42.073629 Tz (a ) Tj 0.269271 0 Td 28.049086 Tz (\) ) Tj 0.420736 0 Td 46.748477 Tz (comprises ) Tj 2.793689 0 Td 62.642959 Tz (SEQ ) Tj 1.380015 0 Td 51.890809 Tz (ID ) Tj 0.858302 0 Td 74.330078 Tz (NO ) Tj 0.959279 0 Td 11.219634 Tz (: ) Tj 0.185124 0 Td 28.049086 Tz (1 ) Tj 0.286101 0 Td 14.024543 Tz (, ) Tj 0.353418 0 Td 44.878537 Tz (2 ) Tj 0.31976 0 Td 14.024543 Tz (, ) Tj 0.353418 0 Td 44.878537 Tz (4 ) Tj 0.336589 0 Td 14.024543 Tz (, ) Tj 0.370248 0 Td 39.26872 Tz (5 ) Tj 0.30293 0 Td 14.024543 Tz (, ) Tj 0.353418 0 Td 43.476083 Tz (or ) Tj 0.757325 0 Td 42.073629 Tz (6 ) Tj 0.31976 0 Td 14.024543 Tz (; ) Tj 60.457143 0 0 60.457143 0 2785.298692 Tm 5.954631 0 Td 44.108381 Tz (transforming ) Tj 3.423913 0 Td 40.662413 Tz (said ) Tj 1.174386 0 Td 40.800252 Tz (plant ) Tj 1.439036 0 Td 45.486767 Tz (with ) Tj 1.306711 0 Td 48.243541 Tz (an ) Tj 0.793951 0 Td 48.090387 Tz (exogenous ) Tj 2.844991 0 Td 48.932735 Tz (Fhbl ) Tj 1.455577 0 Td 42.139256 Tz (nucleic ) Tj 3.688563 0 Td 27.567738 Tz (\( ) Tj 0.181947 0 Td 46.865154 Tz (b ) Tj 0.330813 0 Td 27.567738 Tz (\) ) Tj 0.380435 0 Td 44.108381 Tz (has ) Tj 1.04206 0 Td 34.459672 Tz (at ) Tj 0.645085 0 Td 36.940769 Tz (least ) Tj 1.339792 0 Td 45.486767 Tz (95 ) Tj 0.612004 0 Td 79.94644 Tz (% ) Tj 0.727788 0 Td 46.520558 Tz (sequence ) Tj 2.448015 0 Td 38.93943 Tz (identity ) Tj 2.06758 0 Td 38.594833 Tz (to ) Tj 0.727788 0 Td 61.567948 Tz (SEQ ) Tj 1.339792 0 Td 52.378702 Tz (ID ) Tj 0.843573 0 Td 73.054505 Tz (NO ) Tj 0.942817 0 Td 11.027095 Tz (: ) Tj 0.181947 0 Td 27.567738 Tz (1 ) Tj 0.281191 0 Td 13.783869 Tz (, ) Tj 56.785714 0 0 56.785714 0 2747.728261 Tm 7.008805 0 Td 45.492662 Tz (acid ) Tj 1.355975 0 Td 49.528302 Tz (encoding ) Tj 2.659119 0 Td 44.025157 Tz (a ) Tj 0.528302 0 Td 44.863732 Tz (protein ) Tj 2.130818 0 Td 39.622642 Tz (to ) Tj 0.757233 0 Td 44.612159 Tz (yield ) Tj 1.602516 0 Td 44.025157 Tz (a ) Tj 0.528302 0 Td 48.294263 Tz (transformed ) Tj 3.433962 0 Td 45.199161 Tz (plant ) Tj 1.303145 0 Td 29.350105 Tz (, ) Tj 0.722013 0 Td 32.285115 Tz (5 ) Tj 2.130818 0 Td 46.960168 Tz (2 ) Tj 0.334591 0 Td 14.675052 Tz (, ) Tj 0.369811 0 Td 46.960168 Tz (4 ) Tj 0.352201 0 Td 14.675052 Tz (, ) Tj 0.387421 0 Td 41.090147 Tz (5 ) Tj 0.334591 0 Td 14.675052 Tz (, ) Tj 0.352201 0 Td 45.492662 Tz (or ) Tj 0.792453 0 Td 44.025157 Tz (6 ) Tj 0.352201 0 Td 14.675052 Tz (; ) Tj 63.492063 0 0 63.492063 0 2700.049391 Tm 6.25275 0 Td 45.375 Tz (wherein ) Tj 2.18925 0 Td 39.375 Tz (the ) Tj 1.02375 0 Td 40.6875 Tz (nucleotide ) Tj 2.772 0 Td 44.296875 Tz (sequence ) Tj 2.44125 0 Td 44.625 Tz (of ) Tj 0.80325 0 Td 38.71875 Tz (said ) Tj 1.2285 0 Td 46.083333 Tz (exogenous ) Tj 4.3155 0 Td 26.25 Tz (\( ) Tj 0.189 0 Td 36.75 Tz (c ) Tj 0.252 0 Td 26.25 Tz (\) ) Tj 0.3465 0 Td 43.875 Tz (encodes ) Tj 2.03175 0 Td 39.375 Tz (a ) Tj 0.378 0 Td 39.75 Tz (protein ) Tj 1.827 0 Td 43.575 Tz (comprising ) Tj 2.772 0 Td 39.375 Tz (the ) Tj 0.86625 0 Td 47.775 Tz (amino ) Tj 1.6065 0 Td 40.6875 Tz (acid ) Tj 1.134 0 Td 44.296875 Tz (sequence ) Tj 47.142857 0 0 47.142857 0 2669.790698 Tm 8.4 0 Td 53.535354 Tz (nucleic ) Tj 2.566667 0 Td 54.79798 Tz (acid ) Tj 1.378788 0 Td 14.141414 Tz (: ) Tj 54.285714 0 0 54.285714 0 2651.566667 Tm 25.273684 0 Td 50.657895 Tz (of ) Tj 0.810526 0 Td 69.590643 Tz (SEQ ) Tj 1.547368 0 Td 44.517544 Tz (ID ) Tj 0.902632 0 Td 81.359649 Tz (NO ) Tj 1.05 0 Td 12.280702 Tz (: ) Tj 0.386842 0 Td 46.052632 Tz (3 ) Tj 0.368421 0 Td 15.350877 Tz (, ) Tj 0.386842 0 Td 49.122807 Tz (7 ) Tj 0.368421 0 Td 15.350877 Tz (, ) Tj 0.386842 0 Td 46.052632 Tz (8 ) Tj 0.35 0 Td 15.350877 Tz (, ) Tj 0.386842 0 Td 47.587719 Tz (or ) Tj 0.810526 0 Td 46.052632 Tz (9 ) Tj 0.368421 0 Td 15.350877 Tz (; ) Tj 0.386842 0 Td 47.587719 Tz (or ) Tj 61.428571 0 0 61.428571 0 2621.835095 Tm 6.495349 0 Td 27.131783 Tz (\( ) Tj 0.17907 0 Td 40.697674 Tz (a ) Tj 0.276744 0 Td 27.131783 Tz (\) ) Tj 0.406977 0 Td 44.918174 Tz (comprises ) Tj 2.686047 0 Td 61.498708 Tz (SEQ ) Tj 1.334884 0 Td 51.550388 Tz (ID ) Tj 0.830233 0 Td 71.899225 Tz (NO ) Tj 0.927907 0 Td 10.852713 Tz (: ) Tj 0.195349 0 Td 27.131783 Tz (1 ) Tj 0.260465 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 43.410853 Tz (2 ) Tj 0.325581 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 43.410853 Tz (4 ) Tj 0.309302 0 Td 13.565891 Tz (, ) Tj 0.35814 0 Td 37.984496 Tz (5 ) Tj 0.309302 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 40.697674 Tz (or ) Tj 0.716279 0 Td 40.697674 Tz (6 ) Tj 0.325581 0 Td 13.565891 Tz (; ) Tj 61.428571 0 0 61.428571 0 2608.715743 Tm 21.732558 0 Td 27.131783 Tz (\( ) Tj 0.195349 0 Td 48.837209 Tz (d ) Tj 0.309302 0 Td 27.131783 Tz (\) ) Tj 0.472093 0 Td 45.736434 Tz (encodes ) Tj 2.230233 0 Td 40.697674 Tz (a ) Tj 0.537209 0 Td 41.085271 Tz (protein ) Tj 2.002326 0 Td 45.671835 Tz (having ) Tj 1.937209 0 Td 35.271318 Tz (at ) Tj 0.716279 0 Td 36.899225 Tz (least ) Tj 1.416279 0 Td 44.767442 Tz (95 ) Tj 0.586047 0 Td 78.682171 Tz (% ) Tj 0.781395 0 Td 49.379845 Tz (amino ) Tj 1.806977 0 Td 41.375969 Tz (acid ) Tj 60 0 0 60 0 2581.245255 Tm 6.65 0 Td 27.777778 Tz (\( ) Tj 0.25 0 Td 27.777778 Tz (b ) Tj 0.25 0 Td 27.777778 Tz (\) ) Tj 0.333333 0 Td 44.444444 Tz (has ) Tj 0.983333 0 Td 36.111111 Tz (at ) Tj 0.583333 0 Td 37.222222 Tz (least ) Tj 1.3 0 Td 45.833333 Tz (95 ) Tj 0.6 0 Td 80.555556 Tz (% ) Tj 0.683333 0 Td 46.527778 Tz (sequence ) Tj 2.4 0 Td 39.236111 Tz (identity ) Tj 2.033333 0 Td 37.5 Tz (to ) Tj 0.65 0 Td 62.962963 Tz (SEQ ) Tj 1.3 0 Td 52.777778 Tz (ID ) Tj 0.783333 0 Td 73.611111 Tz (NO ) Tj 0.95 0 Td 11.111111 Tz (: ) Tj 0.183333 0 Td 27.777778 Tz (1 ) Tj 0.283333 0 Td 13.888889 Tz (, ) Tj 61.428571 0 0 61.428571 0 2564.446602 Tm 22.334884 0 Td 37.984496 Tz (identity ) Tj 2.051163 0 Td 36.627907 Tz (to ) Tj 0.7 0 Td 61.498708 Tz (SEQ ) Tj 1.334884 0 Td 51.550388 Tz (ID ) Tj 0.830233 0 Td 71.899225 Tz (NO ) Tj 0.927907 0 Td 10.852713 Tz (: ) Tj 0.34186 0 Td 40.697674 Tz (3 ) Tj 0.325581 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 43.410853 Tz (7 ) Tj 0.309302 0 Td 13.565891 Tz (, ) Tj 0.35814 0 Td 40.697674 Tz (8 ) Tj 0.309302 0 Td 13.565891 Tz (, ) Tj 0.34186 0 Td 40.697674 Tz (or ) Tj 0.716279 0 Td 40.697674 Tz (9 ) Tj 0.325581 0 Td 10.852713 Tz (. ) Tj 51.428571 0 0 51.428571 0 2541 Tm 8.458333 0 Td 51.851852 Tz (2 ) Tj 0.388889 0 Td 16.203704 Tz (, ) Tj 0.408333 0 Td 51.851852 Tz (4 ) Tj 0.388889 0 Td 16.203704 Tz (, ) Tj 0.408333 0 Td 45.37037 Tz (5 ) Tj 0.369444 0 Td 16.203704 Tz (, ) Tj 0.408333 0 Td 50.231481 Tz (or ) Tj 0.855556 0 Td 48.611111 Tz (6 ) Tj 0.388889 0 Td 16.203704 Tz (; ) Tj 56.753247 0 0 56.753247 0 2522.803303 Tm 23.522883 0 Td 42.09255 Tz (12. ) Tj 1.110069 0 Td 54.818205 Tz (The ) Tj 1.32151 0 Td 54.328757 Tz (method ) Tj 2.290618 0 Td 52.860412 Tz (of ) Tj 0.863387 0 Td 48.161709 Tz (claim ) Tj 1.850114 0 Td 35.240275 Tz (11 ) Tj 0.563844 0 Td 14.683448 Tz (, ) Tj 0.440503 0 Td 49.923722 Tz (wherein ) Tj 2.51968 0 Td 36.708619 Tz (said ) Tj 1.30389 0 Td 49.923722 Tz (progeny ) Tj 2.484439 0 Td 30.83524 Tz (is ) Tj 58.571429 0 0 58.571429 0 2499.84507 Tm 6.812195 0 Td 28.455285 Tz (\( ) Tj 0.187805 0 Td 39.837398 Tz (c ) Tj 0.290244 0 Td 28.455285 Tz (\) ) Tj 0.631707 0 Td 47.96748 Tz (encodes ) Tj 2.458537 0 Td 42.682927 Tz (a ) Tj 0.682927 0 Td 43.089431 Tz (protein ) Tj 2.236585 0 Td 47.520325 Tz (comprising ) Tj 3.260976 0 Td 43.631436 Tz (the ) Tj 1.212195 0 Td 51.788618 Tz (amino ) Tj 2.014634 0 Td 44.105691 Tz (acid ) Tj 59.387755 0 0 59.387755 0 2479.502804 Tm 21.805842 0 Td 53.321879 Tz (homozygous ) Tj 3.45189 0 Td 40.225277 Tz (for ) Tj 0.959794 0 Td 40.693013 Tz (said ) Tj 1.195533 0 Td 50.515464 Tz (Fhbl ) Tj 1.498625 0 Td 42.497136 Tz (nucleic ) Tj 2.037457 0 Td 43.499427 Tz (acid ) Tj 1.094502 0 Td 11.225659 Tz (. ) Tj 54.732143 0 0 54.732143 0 2458.014799 Tm 7.947798 0 Td 51.386623 Tz (sequence ) Tj 2.722349 0 Td 51.767265 Tz (of ) Tj 0.822186 0 Td 68.007975 Tz (SEQ ) Tj 1.498206 0 Td 56.334965 Tz (ID ) Tj 0.931811 0 Td 80.69603 Tz (NO ) Tj 1.041436 0 Td 12.180533 Tz (: ) Tj 0.365416 0 Td 45.676998 Tz (3 ) Tj 0.365416 0 Td 15.225666 Tz (, ) Tj 0.383687 0 Td 48.722132 Tz (7 ) Tj 0.365416 0 Td 15.225666 Tz (, ) Tj 0.401958 0 Td 45.676998 Tz (8 ) Tj 0.328874 0 Td 15.225666 Tz (, ) Tj 0.383687 0 Td 47.199565 Tz (or ) Tj 0.822186 0 Td 45.676998 Tz (9 ) Tj 0.347145 0 Td 15.225666 Tz (; ) Tj 0.383687 0 Td 47.199565 Tz (or ) Tj 59.714286 0 0 59.714286 0 2435.889037 Tm 22.356459 0 Td 40.005316 Tz (13. ) Tj 0.971292 0 Td 52.099947 Tz (The ) Tj 1.155502 0 Td 52.565125 Tz (method ) Tj 2.110048 0 Td 47.448166 Tz (of ) Tj 0.720096 0 Td 45.773525 Tz (claim ) Tj 1.607656 0 Td 44.657097 Tz (9 ) Tj 0.334928 0 Td 13.955343 Tz (, ) Tj 0.334928 0 Td 40.669856 Tz (further ) Tj 1.909091 0 Td 46.610845 Tz (comprising ) Tj 3.047847 0 Td 40.315435 Tz (selecting ) Tj 59.010989 0 0 59.010989 0 2414.963397 Tm 6.744507 0 Td 28.243327 Tz (\( ) Tj 0.186406 0 Td 50.837989 Tz (d ) Tj 0.321974 0 Td 28.243327 Tz (\) ) Tj 0.42365 0 Td 47.61018 Tz (encodes ) Tj 2.270764 0 Td 42.364991 Tz (a ) Tj 0.474488 0 Td 42.364991 Tz (protein ) Tj 2.016574 0 Td 47.542934 Tz (having ) Tj 1.94879 0 Td 35.304159 Tz (at ) Tj 0.694786 0 Td 37.281192 Tz (least ) Tj 1.372626 0 Td 46.60149 Tz (95 ) Tj 0.627002 0 Td 81.905649 Tz (% ) Tj 0.745624 0 Td 51.402855 Tz (amino ) Tj 1.796276 0 Td 43.777157 Tz (acid ) Tj 57.142857 0 0 57.142857 0 2374.183575 Tm 7.6125 0 Td 41.197917 Tz (identity ) Tj 2.205 0 Td 40.833333 Tz (to ) Tj 0.77 0 Td 65.138889 Tz (SEQ ) Tj 1.435 0 Td 53.958333 Tz (ID ) Tj 0.8925 0 Td 77.291667 Tz (NO ) Tj 0.9975 0 Td 11.666667 Tz (: ) Tj 0.3675 0 Td 43.75 Tz (3 ) Tj 0.3325 0 Td 14.583333 Tz (, ) Tj 0.3675 0 Td 46.666667 Tz (7 ) Tj 0.35 0 Td 14.583333 Tz (, ) Tj 0.385 0 Td 43.75 Tz (8 ) Tj 0.315 0 Td 14.583333 Tz (, ) Tj 0.3675 0 Td 45.208333 Tz (or ) Tj 0.7875 0 Td 43.75 Tz (9 ) Tj 0.315 0 Td 14.583333 Tz (, ) Tj 60 0 0 60 0 2390.236735 Tm 21.616667 0 Td 36.111111 Tz (at ) Tj 0.733333 0 Td 37.222222 Tz (least ) Tj 1.416667 0 Td 48.148148 Tz (one ) Tj 1.166667 0 Td 41.111111 Tz (plant ) Tj 1.533333 0 Td 50 Tz (from ) Tj 1.5 0 Td 40.972222 Tz (said ) Tj 1.25 0 Td 48.412698 Tz (progeny ) Tj 2.333333 0 Td 38.194444 Tz (that ) Tj 1.216667 0 Td 46.296296 Tz (comprises ) Tj 2.833333 0 Td 40.277778 Tz (said ) Tj 76.122449 0 0 76.122449 0 2331.989641 Tm 4.768633 0 Td 35.031278 Tz (thereby ) Tj 1.615818 0 Td 33.279714 Tz (increasing ) Tj 2.023056 0 Td 33.571641 Tz (the ) Tj 0.709383 0 Td 32.403932 Tz (resistance ) Tj 2.036193 0 Td 40.504915 Tz (of ) Tj 0.525469 0 Td 32.294459 Tz (said ) Tj 0.880161 0 Td 36.225526 Tz (transformed ) Tj 2.469705 0 Td 32.841823 Tz (plant ) Tj 1.313673 0 Td 28.462913 Tz (15 ) Tj 0.68311 0 Td 38.437097 Tz (exogenous ) Tj 2.259517 0 Td 39.410188 Tz (Fhbl ) Tj 1.156032 0 Td 33.780161 Tz (nucleic ) Tj 1.589544 0 Td 35.031278 Tz (acid ) Tj 0.853887 0 Td 35.031278 Tz (. ) Tj 58.035714 0 0 58.035714 0 2289.687783 Tm 6.840615 0 Td 38.769231 Tz (to ) Tj 0.723692 0 Td 67.008547 Tz (FHB ) Tj 1.464615 0 Td 39.846154 Tz (relative ) Tj 2.153846 0 Td 38.769231 Tz (to ) Tj 0.723692 0 Td 43.076923 Tz (a ) Tj 0.499692 0 Td 42.666667 Tz (control ) Tj 2.016 0 Td 44.8 Tz (plant ) Tj 1.275077 0 Td 28.717949 Tz (. ) Tj 61 0 0 61 0 2308.483871 Tm 21.885246 0 Td 39.162113 Tz (14. ) Tj 1.081967 0 Td 51.001821 Tz (The ) Tj 1.262295 0 Td 51.001821 Tz (method ) Tj 2.180328 0 Td 46.448087 Tz (of ) Tj 0.852459 0 Td 44.808743 Tz (claim ) Tj 1.704918 0 Td 45.081967 Tz (13 ) Tj 0.606557 0 Td 13.661202 Tz (, ) Tj 0.47541 0 Td 45.355191 Tz (comprising ) Tj 3.081967 0 Td 41.287189 Tz (detecting ) Tj 2.590164 0 Td 40.983607 Tz (a ) Tj 57.012987 0 0 57.012987 0 2265.99511 Tm 22.731663 0 Td 51.645153 Tz (marker ) Tj 2.034624 0 Td 44.726651 Tz (associated ) Tj 2.841458 0 Td 48.234624 Tz (with ) Tj 1.33303 0 Td 68.21058 Tz (FHB ) Tj 1.29795 0 Td 26.309795 Tz (- ) Tj 0.175399 0 Td 42.972665 Tz (resistance ) Tj 2.771298 0 Td 40.926348 Tz (in ) Tj 0.684055 0 Td 43.118831 Tz (said ) Tj 1.175171 0 Td 50.113895 Tz (progeny ) Tj 2.174943 0 Td 20.463174 Tz (; ) Tj 0.333257 0 Td 51.645153 Tz (and ) Tj 58.571429 0 0 58.571429 0 2248.08871 Tm 6.163415 0 Td 34.146341 Tz (2. ) Tj 0.836585 0 Td 54.065041 Tz (The ) Tj 1.365854 0 Td 53.116531 Tz (method ) Tj 2.304878 0 Td 48.373984 Tz (of ) Tj 0.921951 0 Td 46.666667 Tz (claim ) Tj 1.809756 0 Td 39.837398 Tz (1 ) Tj 0.32439 0 Td 14.227642 Tz (, ) Tj 0.512195 0 Td 49.186992 Tz (wherein ) Tj 2.47561 0 Td 41.260163 Tz (said ) Tj 1.365854 0 Td 42.682927 Tz (plant ) Tj 1.673171 0 Td 32.723577 Tz (is ) Tj 0.819512 0 Td 42.682927 Tz (a ) Tj 52.857143 0 0 52.857143 0 2215.774059 Tm 6.072973 0 Td 55.786556 Tz (monocotyledon ) Tj 4.389189 0 Td 28.378378 Tz (. ) Tj 62.857143 0 0 62.857143 0 2225.833992 Tm 20.65 0 Td 38.299663 Tz (selecting ) Tj 2.386364 0 Td 42.424242 Tz (a ) Tj 0.572727 0 Td 60.10101 Tz (FHB ) Tj 1.240909 0 Td 18.560606 Tz (- ) Tj 0.159091 0 Td 35.353535 Tz (resistant ) Tj 2.227273 0 Td 46.212121 Tz (progeny ) Tj 2.259091 0 Td 39.242424 Tz (plant ) Tj 1.495455 0 Td 44.015152 Tz (comprising ) Tj 2.990909 0 Td 37.121212 Tz (said ) Tj 58.571429 0 0 58.571429 0 2165.08871 Tm 6.163415 0 Td 34.146341 Tz (3. ) Tj 0.836585 0 Td 54.065041 Tz (The ) Tj 1.365854 0 Td 53.116531 Tz (method ) Tj 2.304878 0 Td 48.373984 Tz (of ) Tj 0.921951 0 Td 46.666667 Tz (claim ) Tj 1.809756 0 Td 39.837398 Tz (1 ) Tj 0.32439 0 Td 14.227642 Tz (, ) Tj 0.512195 0 Td 49.186992 Tz (wherein ) Tj 2.47561 0 Td 41.260163 Tz (said ) Tj 1.365854 0 Td 42.682927 Tz (plant ) Tj 1.673171 0 Td 32.723577 Tz (is ) Tj 0.819512 0 Td 42.682927 Tz (a ) Tj 58 0 0 58 0 2183.972973 Tm 22.327586 0 Td 50.766284 Tz (exogenous ) Tj 2.982759 0 Td 51.724138 Tz (Fhb1 ) Tj 1.517241 0 Td 44.334975 Tz (nucleic ) Tj 2.12069 0 Td 42.385057 Tz (acid ) Tj 1.137931 0 Td 25.862069 Tz (. ) Tj 54.285714 0 0 54.285714 0 2135.60221 Tm 5.931579 0 Td 48.00638 Tz (dicotyledon ) Tj 3.242105 0 Td 27.631579 Tz (. ) Tj 58.571429 0 0 58.571429 0 2141.406685 Tm 22.792683 0 Td 40.785908 Tz (15. ) Tj 1.041463 0 Td 54.065041 Tz (The ) Tj 1.263415 0 Td 53.116531 Tz (method ) Tj 2.202439 0 Td 48.373984 Tz (of ) Tj 0.802439 0 Td 46.666667 Tz (claim ) Tj 1.707317 0 Td 39.837398 Tz (1 ) Tj 0.32439 0 Td 14.227642 Tz (, ) Tj 0.392683 0 Td 49.186992 Tz (wherein ) Tj 2.373171 0 Td 41.260163 Tz (said ) Tj 1.263415 0 Td 45.528455 Tz (transforming ) Tj 58.571429 0 0 58.571429 0 2079.922438 Tm 6.163415 0 Td 34.146341 Tz (4. ) Tj 0.665854 0 Td 53.116531 Tz (The ) Tj 1.178049 0 Td 53.590786 Tz (method ) Tj 2.134146 0 Td 48.373984 Tz (of ) Tj 0.734146 0 Td 46.666667 Tz (claim ) Tj 1.639024 0 Td 39.837398 Tz (1 ) Tj 0.32439 0 Td 14.227642 Tz (, ) Tj 0.32439 0 Td 49.186992 Tz (wherein ) Tj 2.304878 0 Td 41.260163 Tz (said ) Tj 1.195122 0 Td 42.113821 Tz (plant ) Tj 1.502439 0 Td 31.300813 Tz (is ) Tj 0.64878 0 Td 42.327236 Tz (selected ) Tj 60 0 0 60 0 2102.40678 Tm 21.6 0 Td 46.296296 Tz (comprises ) Tj 2.7 0 Td 43.434343 Tz (introducing ) Tj 3.033333 0 Td 38.888889 Tz (into ) Tj 1.133333 0 Td 40.277778 Tz (said ) Tj 1.133333 0 Td 41.111111 Tz (plant ) Tj 1.4 0 Td 44.444444 Tz (a ) Tj 0.433333 0 Td 44.444444 Tz (heterologous ) Tj 3.333333 0 Td 60 Tz (recom ) Tj 62.857143 0 0 62.857143 0 2042.273438 Tm 5.138636 0 Td 47.727273 Tz (from ) Tj 1.336364 0 Td 39.772727 Tz (the ) Tj 0.938636 0 Td 45.075758 Tz (group ) Tj 1.590909 0 Td 39.772727 Tz (consisting ) Tj 2.609091 0 Td 45.075758 Tz (of ) Tj 0.7 0 Td 41.098485 Tz (grains ) Tj 1.415909 0 Td 26.515152 Tz (, ) Tj 0.381818 0 Td 46.212121 Tz (legumes ) Tj 2.004545 0 Td 13.257576 Tz (, ) Tj 0.334091 0 Td 46.843434 Tz (and ) Tj 1.034091 0 Td 40.656566 Tz (tubers ) Tj 1.463636 0 Td 18.560606 Tz (. ) Tj 61.428571 0 0 61.428571 0 2059.288321 Tm 21.097674 0 Td 42.054264 Tz (binant ) Tj 1.709302 0 Td 43.139535 Tz (expression ) Tj 2.767442 0 Td 39.001938 Tz (cassette ) Tj 2.067442 0 Td 45.310078 Tz (comprising ) Tj 2.930233 0 Td 40.01938 Tz (said ) Tj 1.139535 0 Td 47.329888 Tz (exogenous ) Tj 2.767442 0 Td 48.837209 Tz (Fhbl ) Tj 48.571429 0 0 48.571429 0 2019 Tm 26.682353 0 Td 51.960784 Tz (nucleic ) Tj 2.491176 0 Td 53.186275 Tz (acid ) Tj 1.338235 0 Td 13.72549 Tz (. ) Tj 57.142857 0 0 57.142857 0 1997.819945 Tm 6.3175 0 Td 35 Tz (5. ) Tj 0.6825 0 Td 54.444444 Tz (The ) Tj 1.2075 0 Td 54.930556 Tz (method ) Tj 2.1875 0 Td 49.583333 Tz (of ) Tj 0.7525 0 Td 47.833333 Tz (claim ) Tj 1.68 0 Td 40.833333 Tz (1 ) Tj 0.3325 0 Td 14.583333 Tz (, ) Tj 0.3325 0 Td 50.416667 Tz (wherein ) Tj 2.3625 0 Td 42.291667 Tz (said ) Tj 1.225 0 Td 43.166667 Tz (plant ) Tj 1.54 0 Td 32.083333 Tz (is ) Tj 0.665 0 Td 43.385417 Tz (selected ) Tj 58.142857 0 0 58.142857 0 1975.273639 Tm 22.960688 0 Td 41.086541 Tz (16. ) Tj 1.083538 0 Td 54.463554 Tz (The ) Tj 1.289926 0 Td 53.030303 Tz (method ) Tj 2.253071 0 Td 48.730549 Tz (of ) Tj 0.842752 0 Td 45.864046 Tz (claim ) Tj 1.823096 0 Td 42.997543 Tz (15 ) Tj 0.584767 0 Td 14.332514 Tz (, ) Tj 0.429975 0 Td 49.140049 Tz (wherein ) Tj 2.407862 0 Td 42.280917 Tz (said ) Tj 1.324324 0 Td 45.577396 Tz (expression ) Tj 60 0 0 60 0 1957.682338 Tm 5.383333 0 Td 50 Tz (from ) Tj 1.366667 0 Td 41.666667 Tz (the ) Tj 0.95 0 Td 46.666667 Tz (group ) Tj 1.616667 0 Td 41.666667 Tz (consisting ) Tj 2.7 0 Td 47.222222 Tz (of ) Tj 0.666667 0 Td 50.555556 Tz (wheat ) Tj 1.483333 0 Td 25 Tz (, ) Tj 0.35 0 Td 41.666667 Tz (oat ) Tj 0.783333 0 Td 13.888889 Tz (, ) Tj 0.3 0 Td 40.740741 Tz (barley ) Tj 1.483333 0 Td 27.777778 Tz (, ) Tj 0.35 0 Td 38.888889 Tz (rice ) Tj 0.966667 0 Td 13.888889 Tz (, ) Tj 0.3 0 Td 48.888889 Tz (maize ) Tj 1.516667 0 Td 13.888889 Tz (, ) Tj 57.142857 0 0 57.142857 0 1916.77305 Tm 5.635 0 Td 42.291667 Tz (millet ) Tj 1.5575 0 Td 14.583333 Tz (, ) Tj 0.28 0 Td 49.583333 Tz (rye ) Tj 0.84 0 Td 20.416667 Tz (, ) Tj 0.35 0 Td 47.083333 Tz (sorghum ) Tj 2.205 0 Td 29.166667 Tz (, ) Tj 0.3675 0 Td 36.62037 Tz (triticale ) Tj 1.96 0 Td 26.25 Tz (, ) Tj 0.35 0 Td 53.796296 Tz (buckwheat ) Tj 2.8 0 Td 26.25 Tz (, ) Tj 0.3675 0 Td 49.583333 Tz (quinoa ) Tj 1.715 0 Td 29.166667 Tz (, ) Tj 0.4025 0 Td 48.489583 Tz (soybeans ) Tj 2.3975 0 Td 14.583333 Tz (, ) Tj 0.5425 0 Td 37.916667 Tz (25 ) Tj 60 0 0 60 0 1931.13308 Tm 21.616667 0 Td 39.930556 Tz (cassette ) Tj 2.15 0 Td 30.555556 Tz (is ) Tj 0.616667 0 Td 44.444444 Tz (introduced ) Tj 2.883333 0 Td 38.194444 Tz (into ) Tj 1.2 0 Td 40.277778 Tz (said ) Tj 1.166667 0 Td 41.666667 Tz (plant ) Tj 1.466667 0 Td 41.666667 Tz (via ) Tj 0.966667 0 Td 38.888889 Tz (particle ) Tj 2.083333 0 Td 58.333333 Tz (bombard ) Tj 60 0 0 60 0 1874.611538 Tm 5.366667 0 Td 46.666667 Tz (beans ) Tj 1.45 0 Td 13.888889 Tz (, ) Tj 0.35 0 Td 45.138889 Tz (peas ) Tj 1.133333 0 Td 13.888889 Tz (, ) Tj 0.366667 0 Td 36.904762 Tz (alfalfa ) Tj 1.533333 0 Td 25 Tz (, ) Tj 0.416667 0 Td 43.055556 Tz (potatoes ) Tj 2.05 0 Td 25 Tz (, ) Tj 0.433333 0 Td 46.111111 Tz (sweet ) Tj 1.6 0 Td 43.055556 Tz (potatoes ) Tj 2.116667 0 Td 13.888889 Tz (, ) Tj 0.366667 0 Td 45.238095 Tz (cassava ) Tj 1.9 0 Td 16.666667 Tz (, ) Tj 0.366667 0 Td 50 Tz (and ) Tj 60 0 0 60 0 1894.680437 Tm 21.6 0 Td 52.083333 Tz (ment ) Tj 1.3 0 Td 22.222222 Tz (- ) Tj 0.066667 0 Td 49.305556 Tz (mediated ) Tj 2.733333 0 Td 41.666667 Tz (delivery ) Tj 1.933333 0 Td 27.777778 Tz (, ) Tj 0.5 0 Td 45.512821 Tz (Agrobacterium ) Tj 3.85 0 Td 27.777778 Tz (- ) Tj 0.083333 0 Td 48.611111 Tz (mediated ) Tj 2.7 0 Td 43.981481 Tz (uptake ) Tj 1.616667 0 Td 27.777778 Tz (, ) Tj 60 0 0 60 0 1850.6225 Tm 21.616667 0 Td 56.25 Tz (PEG- ) Tj 1.683333 0 Td 41.666667 Tz (or ) Tj 0.8 0 Td 41.111111 Tz (electroporation ) Tj 3.816667 0 Td 27.777778 Tz (- ) Tj 0.05 0 Td 50 Tz (mediated ) Tj 2.683333 0 Td 46.296296 Tz (uptake ) Tj 1.633333 0 Td 27.777778 Tz (, ) Tj 0.483333 0 Td 37.222222 Tz (viral ) Tj 1.45 0 Td 39.197531 Tz (infection ) Tj 2.166667 0 Td 25 Tz (, ) Tj 45.714286 0 0 45.714286 0 1838.092593 Tm 7.04375 0 Td 57.118056 Tz (yam ) Tj 1.465625 0 Td 25.520833 Tz (. ) Tj 56.883117 0 0 56.883117 0 1792.64898 Tm 6.363927 0 Td 33.694825 Tz (6. ) Tj 0.650457 0 Td 55.669711 Tz (The ) Tj 1.213014 0 Td 54.693049 Tz (method ) Tj 2.197489 0 Td 48.344749 Tz (of ) Tj 0.738356 0 Td 48.05175 Tz (claim ) Tj 1.687671 0 Td 41.019787 Tz (1 ) Tj 0.316438 0 Td 14.649924 Tz (, ) Tj 0.334018 0 Td 50.64688 Tz (wherein ) Tj 2.355708 0 Td 43.217275 Tz (said ) Tj 1.248174 0 Td 51.111957 Tz (exogenous ) Tj 3.006164 0 Td 52.739726 Tz (Fhb1 ) Tj 64.285714 0 0 64.285714 0 1808.56129 Tm 20.175556 0 Td 43.209877 Tz (and ) Tj 0.902222 0 Td 20.740741 Tz (/ ) Tj 0.186667 0 Td 32.407407 Tz (or ) Tj 0.575556 0 Td 40.185185 Tz (microinjection ) Tj 3.375556 0 Td 25.925926 Tz (. ) Tj 60 0 0 60 0 1750.308824 Tm 5.366667 0 Td 42.460317 Tz (nucleic ) Tj 2.15 0 Td 43.055556 Tz (acid ) Tj 1.366667 0 Td 31.944444 Tz (is ) Tj 0.766667 0 Td 40.277778 Tz (stably ) Tj 1.816667 0 Td 43.518519 Tz (incorporated ) Tj 3.483333 0 Td 38.194444 Tz (into ) Tj 1.283333 0 Td 41.666667 Tz (the ) Tj 1.1 0 Td 45.707071 Tz (transformed ) Tj 62.857143 0 0 62.857143 0 1762.814136 Tm 21.238636 0 Td 38.005051 Tz (17. ) Tj 0.906818 0 Td 71.590909 Tz (A ) Tj 0.604545 0 Td 45.075758 Tz (recombinant ) Tj 3.197727 0 Td 41.540404 Tz (vector ) Tj 1.718182 0 Td 38.005051 Tz (for ) Tj 0.906818 0 Td 40.833333 Tz (conferring ) Tj 2.656818 0 Td 48.058712 Tz (Fusarium ) Tj 2.545455 0 Td 47.064394 Tz (head ) Tj 59.047619 0 0 59.047619 0 1711.969432 Tm 5.453226 0 Td 40.725806 Tz (plants ) Tj 1.947581 0 Td 55.981183 Tz (genome ) Tj 1.981452 0 Td 25.403226 Tz (. ) Tj 62.857143 0 0 62.857143 0 1722.890566 Tm 20.618182 0 Td 38.44697 Tz (blight ) Tj 1.606818 0 Td 26.515152 Tz (\( ) Tj 0.190909 0 Td 60.984848 Tz (FHB ) Tj 1.145455 0 Td 26.515152 Tz (\) ) Tj 0.381818 0 Td 38.977273 Tz (resistance ) Tj 2.545455 0 Td 38.44697 Tz (in ) Tj 0.652273 0 Td 39.772727 Tz (a ) Tj 0.445455 0 Td 42.424242 Tz (plant ) Tj 1.145455 0 Td 26.515152 Tz (, ) Tj 0.413636 0 Td 38.44697 Tz (said ) Tj 1.113636 0 Td 44.834711 Tz (recombinant ) Tj 3.165909 0 Td 41.540404 Tz (vector ) Tj 52.857143 0 0 52.857143 0 1667 Tm 6.82973 0 Td 37.837838 Tz (7. ) Tj 0.889189 0 Td 58.858859 Tz (The ) Tj 1.456757 0 Td 58.858859 Tz (method ) Tj 2.516216 0 Td 53.603604 Tz (of ) Tj 0.964865 0 Td 51.711712 Tz (claim ) Tj 1.967568 0 Td 44.144144 Tz (1 ) Tj 0.359459 0 Td 15.765766 Tz (, ) Tj 0.510811 0 Td 54.504505 Tz (wherein ) Tj 2.686486 0 Td 46.509009 Tz (said ) Tj 1.475676 0 Td 52.170352 Tz (transformed ) Tj 60 0 0 60 0 1684.305211 Tm 21.616667 0 Td 46.388889 Tz (comprising ) Tj 2.966667 0 Td 48.611111 Tz (an ) Tj 0.75 0 Td 40.277778 Tz (isolated ) Tj 2.1 0 Td 49.305556 Tz (Fhbl ) Tj 1.433333 0 Td 42.063492 Tz (nucleic ) Tj 1.966667 0 Td 43.055556 Tz (acid ) Tj 1.2 0 Td 44.791667 Tz (operably ) Tj 2.35 0 Td 43.055556 Tz (linked ) Tj 1.7 0 Td 37.5 Tz (to ) Tj 61.428571 0 0 61.428571 0 1624.912658 Tm 5.24186 0 Td 38.75969 Tz (plant's ) Tj 1.855814 0 Td 52.45478 Tz (genome ) Tj 2.1 0 Td 44.918174 Tz (comprises ) Tj 2.62093 0 Td 51.550388 Tz (more ) Tj 1.432558 0 Td 43.410853 Tz (than ) Tj 1.237209 0 Td 47.028424 Tz (one ) Tj 1.04186 0 Td 48.837209 Tz (copy ) Tj 1.367442 0 Td 46.124031 Tz (of ) Tj 0.667442 0 Td 40.697674 Tz (the ) Tj 0.944186 0 Td 55.620155 Tz (exog ) Tj 61.428571 0 0 61.428571 0 1641.964413 Tm 21.113953 0 Td 40.697674 Tz (a ) Tj 0.374419 0 Td 43.410853 Tz (heterologous ) Tj 3.272093 0 Td 46.802326 Tz (promoter ) Tj 2.213953 0 Td 24.418605 Tz (, ) Tj 0.276744 0 Td 46.511628 Tz (wherein ) Tj 2.083721 0 Td 40.697674 Tz (the ) Tj 0.862791 0 Td 42.054264 Tz (nucleotide ) Tj 2.686047 0 Td 45.784884 Tz (sequence ) Tj 2.344186 0 Td 46.124031 Tz (of ) Tj 45.714286 0 0 45.714286 0 1604 Tm 28.39375 0 Td 53.776042 Tz (said ) Tj 1.553125 0 Td 55.208333 Tz (nucleic ) Tj 2.646875 0 Td 56.510417 Tz (acid ) Tj 1.421875 0 Td 14.583333 Tz (: ) Tj 49.428571 0 0 49.428571 0 1585.683891 Tm 6.514451 0 Td 57.321773 Tz (enous ) Tj 2.023121 0 Td 59.850674 Tz (Fhbl ) Tj 1.780347 0 Td 51.541426 Tz (nucleic ) Tj 2.468208 0 Td 51.421002 Tz (acid ) Tj 1.274566 0 Td 16.859345 Tz (. ) Tj 58.571429 0 0 58.571429 0 1539.884666 Tm 6.163415 0 Td 34.146341 Tz (8. ) Tj 0.614634 0 Td 54.065041 Tz (The ) Tj 1.143902 0 Td 53.116531 Tz (method ) Tj 2.082927 0 Td 48.373984 Tz (of ) Tj 0.7 0 Td 46.666667 Tz (claim ) Tj 1.587805 0 Td 39.837398 Tz (1 ) Tj 0.32439 0 Td 14.227642 Tz (, ) Tj 0.290244 0 Td 49.186992 Tz (wherein ) Tj 2.253659 0 Td 41.260163 Tz (said ) Tj 1.143902 0 Td 46.821877 Tz (transformed ) Tj 3.243902 0 Td 42.682927 Tz (plant ) Tj 58.571429 0 0 58.571429 0 1557.854123 Tm 22.792683 0 Td 28.455285 Tz (\( ) Tj 0.204878 0 Td 42.682927 Tz (a ) Tj 0.273171 0 Td 28.455285 Tz (\) ) Tj 0.426829 0 Td 47.425474 Tz (comprises ) Tj 2.834146 0 Td 63.550136 Tz (SEQ ) Tj 1.4 0 Td 52.642276 Tz (ID ) Tj 0.870732 0 Td 75.406504 Tz (NO ) Tj 0.973171 0 Td 11.382114 Tz (: ) Tj 0.187805 0 Td 28.455285 Tz (1 ) Tj 0.290244 0 Td 14.227642 Tz (, ) Tj 0.358537 0 Td 45.528455 Tz (2 ) Tj 0.32439 0 Td 14.227642 Tz (, ) Tj 0.358537 0 Td 45.528455 Tz (4 ) Tj 0.341463 0 Td 14.227642 Tz (, ) Tj 0.37561 0 Td 39.837398 Tz (5 ) Tj 0.307317 0 Td 14.227642 Tz (, ) Tj 0.358537 0 Td 44.105691 Tz (or ) Tj 0.768293 0 Td 42.682927 Tz (6 ) Tj 0.32439 0 Td 14.227642 Tz (; ) Tj 58.571429 0 0 58.571429 0 1500.663158 Tm 5.514634 0 Td 41.056911 Tz (further ) Tj 1.878049 0 Td 47.109304 Tz (comprises ) Tj 2.731707 0 Td 42.682927 Tz (a ) Tj 0.426829 0 Td 48.848238 Tz (second ) Tj 1.895122 0 Td 49.954833 Tz (exogenous ) Tj 2.868293 0 Td 43.089431 Tz (nucleic ) Tj 1.997561 0 Td 43.394309 Tz (acid ) Tj 1.195122 0 Td 48.373984 Tz (encoding ) Tj 2.731707 0 Td 36.99187 Tz (35 ) Tj 57.142857 0 0 57.142857 0 1515.867052 Tm 23.3625 0 Td 29.166667 Tz (\( ) Tj 0.1925 0 Td 49.583333 Tz (b ) Tj 0.35 0 Td 29.166667 Tz (\) ) Tj 0.4025 0 Td 46.666667 Tz (has ) Tj 1.1025 0 Td 36.458333 Tz (at ) Tj 0.6825 0 Td 39.083333 Tz (least ) Tj 1.4175 0 Td 48.125 Tz (95 ) Tj 0.6475 0 Td 84.583333 Tz (% ) Tj 0.77 0 Td 49.21875 Tz (sequence ) Tj 2.59 0 Td 41.197917 Tz (identity ) Tj 2.1875 0 Td 40.833333 Tz (to ) Tj 0.77 0 Td 65.138889 Tz (SEQ ) Tj 1.4175 0 Td 55.416667 Tz (ID ) Tj 0.8925 0 Td 77.291667 Tz (NO ) Tj 0.9975 0 Td 11.666667 Tz (: ) Tj 0.1925 0 Td 29.166667 Tz (1 ) Tj 0.2975 0 Td 14.583333 Tz (, ) Tj 52.857143 0 0 52.857143 0 1460.12462 Tm 6.110811 0 Td 47.297297 Tz (a ) Tj 0.52973 0 Td 48.348348 Tz (native ) Tj 1.967568 0 Td 46.351351 Tz (resistance ) Tj 3.045946 0 Td 54.391892 Tz (gene ) Tj 1.343243 0 Td 18.918919 Tz (. ) Tj 51.587302 0 0 51.587302 0 1475.544643 Tm 26.595692 0 Td 51.692308 Tz (2 ) Tj 0.368308 0 Td 16.153846 Tz (, ) Tj 0.407077 0 Td 51.692308 Tz (4 ) Tj 0.387692 0 Td 16.153846 Tz (, ) Tj 0.426462 0 Td 45.230769 Tz (5 ) Tj 0.368308 0 Td 16.153846 Tz (, ) Tj 0.387692 0 Td 50.076923 Tz (or ) Tj 0.872308 0 Td 48.461538 Tz (6 ) Tj 0.387692 0 Td 16.153846 Tz (; ) Tj 59.571429 0 0 59.571429 0 1416.899721 Tm 6.059952 0 Td 33.573141 Tz (9. ) Tj 0.721823 0 Td 52.224887 Tz (The ) Tj 1.22542 0 Td 52.224887 Tz (method ) Tj 2.148681 0 Td 47.56195 Tz (of ) Tj 0.788969 0 Td 45.883293 Tz (claim ) Tj 1.678657 0 Td 39.168665 Tz (1 ) Tj 0.318945 0 Td 13.988809 Tz (, ) Tj 0.402878 0 Td 40.367706 Tz (further ) Tj 1.964029 0 Td 46.722622 Tz (comprising ) Tj 3.105516 0 Td 43.015588 Tz (crossing ) Tj 61.428571 0 0 61.428571 0 1432.750973 Tm 21.732558 0 Td 27.131783 Tz (\( ) Tj 0.195349 0 Td 37.984496 Tz (c ) Tj 0.260465 0 Td 27.131783 Tz (\) ) Tj 0.35814 0 Td 45.348837 Tz (encodes ) Tj 2.1 0 Td 40.697674 Tz (a ) Tj 0.390698 0 Td 41.085271 Tz (protein ) Tj 1.888372 0 Td 45.03876 Tz (comprising ) Tj 2.865116 0 Td 40.697674 Tz (the ) Tj 0.895349 0 Td 49.379845 Tz (amino ) Tj 1.660465 0 Td 42.054264 Tz (acid ) Tj 1.172093 0 Td 45.784884 Tz (sequence ) Tj 60.31746 0 0 60.31746 0 1374.584958 Tm 5.371579 0 Td 40.756579 Tz (said ) Tj 1.326316 0 Td 45.466507 Tz (transformed ) Tj 3.348947 0 Td 40.894737 Tz (plant ) Tj 1.608158 0 Td 45.592105 Tz (with ) Tj 1.458947 0 Td 41.447368 Tz (a ) Tj 0.646579 0 Td 46.973684 Tz (second ) Tj 2.072368 0 Td 40.342105 Tz (plant ) Tj 1.558421 0 Td 38.684211 Tz (to ) Tj 0.845526 0 Td 47.368421 Tz (produce ) Tj 54.285714 0 0 54.285714 0 1391.952663 Tm 25.273684 0 Td 50.657895 Tz (of ) Tj 0.810526 0 Td 69.590643 Tz (SEQ ) Tj 1.528947 0 Td 56.798246 Tz (ID ) Tj 0.921053 0 Td 81.359649 Tz (NO ) Tj 1.05 0 Td 12.280702 Tz (: ) Tj 0.386842 0 Td 46.052632 Tz (3 ) Tj 0.368421 0 Td 15.350877 Tz (, ) Tj 0.386842 0 Td 49.122807 Tz (7 ) Tj 0.368421 0 Td 15.350877 Tz (, ) Tj 0.386842 0 Td 46.052632 Tz (8 ) Tj 0.35 0 Td 15.350877 Tz (, ) Tj 0.386842 0 Td 47.587719 Tz (or ) Tj 0.810526 0 Td 46.052632 Tz (9 ) Tj 0.368421 0 Td 15.350877 Tz (; ) Tj 0.386842 0 Td 47.587719 Tz (or ) Tj 61.428571 0 0 61.428571 0 1349.715743 Tm 21.732558 0 Td 27.131783 Tz (\( ) Tj 0.195349 0 Td 48.837209 Tz (d ) Tj 0.309302 0 Td 27.131783 Tz (\) ) Tj 0.472093 0 Td 45.736434 Tz (encodes ) Tj 2.230233 0 Td 40.697674 Tz (a ) Tj 0.537209 0 Td 41.085271 Tz (protein ) Tj 2.002326 0 Td 45.671835 Tz (having ) Tj 1.937209 0 Td 35.271318 Tz (at ) Tj 0.716279 0 Td 36.899225 Tz (least ) Tj 1.416279 0 Td 44.767442 Tz (95 ) Tj 0.586047 0 Td 78.682171 Tz (% ) Tj 0.781395 0 Td 49.379845 Tz (amino ) Tj 1.806977 0 Td 41.375969 Tz (acid ) Tj 48.571429 0 0 48.571429 0 1337.614173 Tm 6.629412 0 Td 58.823529 Tz (progeny ) Tj 2.470588 0 Td 24.019608 Tz (. ) Tj 55.357143 0 0 55.357143 0 1293.263298 Tm 6.539355 0 Td 42.150538 Tz (10. ) Tj 1.047742 0 Td 57.204301 Tz (The ) Tj 1.282581 0 Td 56.200717 Tz (method ) Tj 2.294194 0 Td 49.677419 Tz (of ) Tj 0.794839 0 Td 49.376344 Tz (claim ) Tj 1.752258 0 Td 48.172043 Tz (9 ) Tj 0.36129 0 Td 15.053763 Tz (, ) Tj 0.36129 0 Td 52.043011 Tz (wherein ) Tj 2.456774 0 Td 44.408602 Tz (said ) Tj 1.300645 0 Td 52.473118 Tz (progeny ) Tj 2.474839 0 Td 56.451613 Tz (com- ) Tj 1.788387 0 Td 42.150538 Tz (40 ) Tj 54.285714 0 0 54.285714 0 1308.650124 Tm 25.255263 0 Td 42.598684 Tz (identity ) Tj 2.357895 0 Td 38.377193 Tz (to ) Tj 0.755263 0 Td 69.590643 Tz (SEQ ) Tj 1.510526 0 Td 58.333333 Tz (ID ) Tj 0.939474 0 Td 70.614035 Tz (NO ) Tj 0.994737 0 Td 21.491228 Tz (: ) Tj 0.460526 0 Td 42.982456 Tz (3 ) Tj 0.35 0 Td 15.350877 Tz (, ) Tj 0.405263 0 Td 46.052632 Tz (7 ) Tj 0.331579 0 Td 15.350877 Tz (, ) Tj 0.405263 0 Td 46.052632 Tz (8 ) Tj 0.35 0 Td 15.350877 Tz (, ) Tj 0.386842 0 Td 46.052632 Tz (or ) Tj 0.810526 0 Td 46.052632 Tz (9 ) Tj 0.368421 0 Td 12.280702 Tz (. ) Tj 60 0 0 60 0 1249.793893 Tm 5.366667 0 Td 39.814815 Tz (prises ) Tj 1.616667 0 Td 36.111111 Tz (at ) Tj 0.616667 0 Td 37.222222 Tz (least ) Tj 1.283333 0 Td 48.611111 Tz (an ) Tj 0.75 0 Td 36.574074 Tz (allele ) Tj 1.5 0 Td 45.833333 Tz (of ) Tj 0.683333 0 Td 40.972222 Tz (said ) Tj 1.133333 0 Td 48.765432 Tz (exogenous ) Tj 2.833333 0 Td 49.305556 Tz (Fhbl ) Tj 1.416667 0 Td 42.063492 Tz (nucleic ) Tj 1.966667 0 Td 42.361111 Tz (acid ) Tj 1.05 0 Td 13.888889 Tz (, ) Tj 55.714286 0 0 55.714286 0 1265 Tm 23.961538 0 Td 42.877493 Tz (18. ) Tj 1.112821 0 Td 56.837607 Tz (The ) Tj 1.328205 0 Td 50.854701 Tz (recombinant ) Tj 3.661538 0 Td 46.866097 Tz (vector ) Tj 1.992308 0 Td 50.854701 Tz (of ) Tj 0.861538 0 Td 49.059829 Tz (claim ) Tj 1.812821 0 Td 52.350427 Tz (17 ) Tj 0.664103 0 Td 14.957265 Tz (, ) Tj 0.448718 0 Td 51.282051 Tz (wherein ) Tj 2.494872 0 Td 43.376068 Tz (said ) Tj 59.84127 0 0 59.84127 0 1210.529566 Tm 5.397613 0 Td 41.080902 Tz (said ) Tj 1.236605 0 Td 48.541114 Tz (progeny ) Tj 2.322812 0 Td 41.777188 Tz (exhibiting ) Tj 2.790716 0 Td 34.814324 Tz (at ) Tj 0.701857 0 Td 37.320955 Tz (least ) Tj 1.387003 0 Td 37.798408 Tz (partial ) Tj 1.854907 0 Td 40.941645 Tz (resistance ) Tj 2.723873 0 Td 37.599469 Tz (to ) Tj 0.7687 0 Td 64.058355 Tz (FHB ) Tj 57.142857 0 0 57.142857 0 1228.237288 Tm 22.68 0 Td 46.666667 Tz (heterologous ) Tj 3.605 0 Td 49.947917 Tz (promoter ) Tj 2.625 0 Td 33.541667 Tz (is ) Tj 0.665 0 Td 43.75 Tz (a ) Tj 0.49 0 Td 48.489583 Tz (pathogen ) Tj 2.5025 0 Td 29.166667 Tz (- ) Tj 0.2275 0 Td 46.666667 Tz (induced ) Tj 2.17 0 Td 49.583333 Tz (promoter ) Tj 2.345 0 Td 26.25 Tz (. ) Tj 59.761905 0 0 59.761905 0 1166.408046 Tm 5.371315 0 Td 39.39243 Tz (relative ) Tj 2.108367 0 Td 37.649402 Tz (to ) Tj 0.702789 0 Td 41.832669 Tz (a ) Tj 0.485259 0 Td 41.434263 Tz (control ) Tj 1.957769 0 Td 44.063745 Tz (plant ) Tj 1.25498 0 Td 27.888446 Tz (. ) Tj 52.857143 0 0 52.857143 0 1184 Tm 25.256757 0 Td 45.195195 Tz (19. ) Tj 1.172973 0 Td 59.90991 Tz (The ) Tj 1.4 0 Td 53.603604 Tz (recombinant ) Tj 3.859459 0 Td 49.399399 Tz (vector ) Tj 2.1 0 Td 53.603604 Tz (of ) Tj 0.908108 0 Td 51.711712 Tz (claim ) Tj 1.910811 0 Td 55.18018 Tz (17 ) Tj 0.7 0 Td 15.765766 Tz (, ) Tj 0.472973 0 Td 54.054054 Tz (wherein ) Tj 2.62973 0 Td 45.720721 Tz (said ) Tj 61.428571 0 0 61.428571 0 1122.918621 Tm 5.893023 0 Td 36.175711 Tz (11. ) Tj 0.87907 0 Td 51.550388 Tz (The ) Tj 1.139535 0 Td 50.645995 Tz (method ) Tj 2.034884 0 Td 46.124031 Tz (of ) Tj 0.7 0 Td 44.496124 Tz (claim ) Tj 1.546512 0 Td 43.410853 Tz (9 ) Tj 0.325581 0 Td 13.565891 Tz (, ) Tj 0.309302 0 Td 46.899225 Tz (wherein ) Tj 2.181395 0 Td 40.01938 Tz (said ) Tj 1.188372 0 Td 46.124031 Tz (second ) Tj 1.855814 0 Td 40.155039 Tz (plant ) Tj 1.416279 0 Td 31.20155 Tz (is ) Tj 65.714286 0 0 65.714286 0 1147.403372 Tm 19.721739 0 Td 40.57971 Tz (heterologous ) Tj 3.256522 0 Td 43.75 Tz (promoter ) Tj 2.404348 0 Td 27.898551 Tz (is ) Tj 0.669565 0 Td 35.507246 Tz (a ) Tj 0.547826 0 Td 36.050725 Tz (constitutively ) Tj 3.180435 0 Td 25.362319 Tz (- ) Tj 0.167391 0 Td 40.016103 Tz (expressed ) Tj 2.617391 0 Td 45.652174 Tz (pro ) Tj 41.428571 0 0 41.428571 0 1105 Tm 31.282759 0 Td 70 Tz (moter ) Tj 2.1 0 Td 24.137931 Tz (. ) Tj 59.857143 0 0 59.857143 0 1085.948565 Tm 5.379475 0 Td 41.76611 Tz (a ) Tj 0.417661 0 Td 42.322991 Tz (transgenic ) Tj 2.72315 0 Td 41.209228 Tz (plant ) Tj 1.403341 0 Td 46.870857 Tz (having ) Tj 1.871122 0 Td 42.694246 Tz (increased ) Tj 2.48926 0 Td 40.930788 Tz (resistance ) Tj 2.622912 0 Td 37.589499 Tz (to ) Tj 0.651551 0 Td 64.969504 Tz (FHB ) Tj 1.369928 0 Td 39.44577 Tz (infec- ) Tj 1.821002 0 Td 37.589499 Tz (45 ) Tj 59 0 0 59 0 1044.16485 Tm 5.440678 0 Td 41.666667 Tz (tion ) Tj 1.016949 0 Td 14.124294 Tz (, ) Tj 0.508475 0 Td 49.905838 Tz (and ) Tj 1.135593 0 Td 47.551789 Tz (having ) Tj 2.050847 0 Td 49.435028 Tz (an ) Tj 0.898305 0 Td 49.591965 Tz (exogenous ) Tj 3.016949 0 Td 50.141243 Tz (Fhbl ) Tj 1.59322 0 Td 42.776433 Tz (nucleic ) Tj 2.152542 0 Td 43.079096 Tz (acid ) Tj 1.372881 0 Td 40.018832 Tz (stably ) Tj 32.857143 0 0 32.857143 0 1716 Tm 37.830435 0 Td 71.014493 Tz (30 ) Tj 27.142857 0 0 27.142857 0 1052 Tm 64.031579 0 Td 79.824561 Tz (* ) Tj 2.063158 0 Td 79.824561 Tz (* ) Tj ET Q endstream endobj xref 4 1 0002925803 00000 n 9 1 0002926073 00000 n 14 1 0002926345 00000 n 19 1 0002926618 00000 n 24 1 0002926891 00000 n 29 1 0002927164 00000 n 34 1 0002927437 00000 n 39 1 0002927710 00000 n 44 1 0002927983 00000 n 49 1 0002928256 00000 n 54 1 0002928530 00000 n 59 1 0002928804 00000 n 64 1 0002929078 00000 n 69 1 0002929352 00000 n 74 1 0002929626 00000 n 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