February 28, 2023
Won Min Park to present Biochemistry and Molecular Biophysics Seminar March 1
Submitted by Biochemistry and Molecular Biophysics
Won Min Park, professor of chemical engineering at 1xbet sports betting , will be the speaker for this week’s Biochemistry and Molecular Biophysics Seminar.Park will present "Building nanostructured biomaterials using coiled-coil protein motifs" at 4 p.m.Wednesday, March 1, in 120 Ackert Hall.
Presentation abstract: Coiled coils are α-helical 1xbet sports betting motifs that form supercoiled complexes. As subunits that oligomerize various 1xbet sports betting complexes in nature, coiled coils play an essential role in creating functional 1xbet sports betting assemblies that are involved in biological processes or that form biological materials. The sequence-to-structure relationships of coiled coils have been understood well over the past three decades, which has led to the de novo design of coiled-coil toolkits with designable specificity, oligomeric state, length and helix orientation. Because of their utility, synthetic coiled coils have been used to construct a variety of engineered 1xbet sports betting assemblies.Park's research group focuses on exploiting the coiled-coil interactions to create nanostructured 1xbet sports betting biomaterials with programmable functionalities. The research team demonstrated the approach of genetic fusion of the synthetic coiled-coil sequences in the topologies that dictated the size, shape and morphology of assemblies or with other 1xbet sports betting domains that modularly incorporated desired biological functions. In particular, the group has studied coiled-coil 1xbet sports betting origami, which is a method to assemble well-defined nanostructures from recombinant proteins of linked-coiled-coil sequences. They also demonstrated the assembly of different classes of biomaterials such as 1xbet sports betting coatings or intracellular architectures that have been used for biosensors or neuroimaging. Theresearch teamwill discuss the extension of this rational approach toward building more complex materials with tunable functionalities.