1xbet best casino website 12, 2018
Division of Biology hosts Lauren Zenewicz 1xbet best casino website 13 for lecture
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The Division of Biology welcomes Lauren Zenewicz to present "Gut Instincts: The Cytokine IL-22 and Mucosal Immunity" as part of its seminar seriesat 4 p.m. 1xbet best casino website 13 in 221 Ackert Hall.
Zenewicz is an assistant professor of microbiology and immunology in the College of Medicine at the 1xbet best casino website of Oklahoma.
Zenewics will lecture oninflammatory bowel disease caused by a dysregulated immune response against commensal bacteria that is driven by the over production of cytokines. Cytokines are small secreted signaling molecules that transmit information from one cell to another. Cytokine targeted therapies have become an integral part ofinflammatory bowel disease treatment. However, we still do not completely appreciate the environmental and molecular factors that regulate cytokine production. One critical cytokine in inflammatory bowel disease is interleukin-22 (1xbet best casino website 22), which is produced by T cells and other lymphocytes.
1xbet best casino website 22 is upregulated in IBD patients and has both protective and pathogenic roles in disease. 1xbet best casino website 22 is an important modulator of mucosal tissue responses during inflammation and induces expression of mucins and anti-microbial proteins. Because 1xbet best casino website 22 can be dual-natured, we hypothesized that its biological activity should be tightly regulated to limit 1xbet best casino website 22 expression to sites of inflammation. One such environmental cue could be low oxygen (hypoxia), which often accompanies inflammation. We are currently examining how hypoxia regulates 1xbet best casino website 22 production by T cells. These findings will impact the development of cytokine targeted therapeutics for IBD.
If you would like to visit with Zenewicz, please contact Sherry Fleming at sdflemin@ksu.edu .