Kansas State University

Minding the mind: How scientists study our changing 1xbet online sports betting

By Jennifer Tidball

We 1xbet online sports betting see plasticity in the world around us.

1xbet online sports betting might look like this: A student studying for a test. An adult adjusting to a hearing aid. A driver trying to remember where the car is parked. A zebrafish memorizing a place with tasty food. A rat learning self-control.

Plasticity is how the 1xbet online sports betting changes with experience, learning or age. It can be a positive change, such as a child learning the alphabet or an adult choosing a salad instead of cake. But plasticity also can have a negative side, such as a person struggling with alcohol abuse or suffering from a degenerative disease.

“Plasticity 1xbet online sports betting be good and it 1xbet online sports betting be bad, but both are important and that’s why we need research on both sides of the coin,” said Kimberly Kirkpatrick, explore 1xbet online spo distinguished professor of Department of psycholo. “It’s important to understand why the 1xbet online sports betting changes because it can help with disease treatment or countermeasures.”

Plasticity is the research focus of the Kansas State University 1xbet online casino Accomplishments, or CNAP.

CNAP is a statewide effort led by K-State to help us understand our changing brains and improve our quality of life. While the center is housed in the K-State psychological sciences department, 1xbet online sports betting involves interdisciplinary researchers from the College of Arts and Sciences, the Carl R. Ice College of Engineering and the College of Veterinary Medicine. CNAP 1xbet online sports betting includes collaborators at the University of Kansas and Wichita State University.

The National Institutes of Health recognizes the importance of neuroscience research and, in 2017, funded CNAP with a prestigious .6 million Centers of Biomedical Research Excellence, or COBRE, grant. 1xbet online sports betting is the largest grant in the history of the psychological sciences department and is only the second time the university has received a COBRE grant. Now early in its third year, the center continues to develop and grow.

“What we have been able to do in two years is huge,” said 1xbet online sports betting , CNAP director. “The enrichment to our research community is substantial and our faculty members are able to take their work to the next level.”

More than 63 collaborators — including faculty members, scientists, postdoctoral researchers, graduate students and undergraduate students — are involved with CNAP and are conducting cognitive, behavioral and neurobiological research on topics such as self-control, alcohol abuse, aging, hearing, memory loss and 1xbet online sports betting .

“Our areas of research are diverse, but plasticity is really the glue that holds it all together,” Kirkpatrick said. “Everything relates to 1xbet online sports betting processes, 1xbet online sports betting health and plasticity in terms of changes that happen in the 1xbet online sports betting over time or with experiences.”

In addition to supporting research, the grant 1xbet online sports betting has funded laboratory upgrades, including a surgery unit, a new histology laboratory and other equipment. The renovations total more than 2,100 square feet in Bluemont Hall and the upgrades have led to new research possibilities.

“These significant improvements in our infrastructure have opened the door to people performing techniques they couldn’t do before,” Kirkpatrick said. “Facilities matter in neuroscience, and now we 1xbet online sports betting recruit top-of-the-line faculty, graduate students and postdoctoral researchers.”

Understanding the 1xbet online sports betting

For her own research, Kirkpatrick is using the upgraded facilities to study two areas: ways to improve self-control and ways that diet affects the 1xbet online sports betting and impulsive behavior.

Self-control is associated with many positive behaviors. 1xbet online sports betting with good self-control are less likely to abuse drugs, are less likely to have attention disorders, are more likely to maintain healthy weight and are more likely to have better financial management.

Kirkpatrick is studying behavior in rats and humans to understand how self-control affects the 1xbet online sports betting . Through time-based interventions, Kirkpatrick’s team has found that rats prefer to wait for a larger treat rather than have a smaller treat immediately. Now the team is doing similar behavioral work with humans through computer games, activities and smartphone apps that help people practice self-control.

Through diet-related research, 1xbet online sports betting has found rats that eat high-fat and high-sugar diets are more likely to engage in impulsive behavior.

“These high-fat or high-sugar diets are causing inflammation in the 1xbet online sports betting and that’s causing damage to cells,” Kirkpatrick said. “Even with a return to a healthy diet, some individuals still have nervous system damage that’s changing their cognitive behavior long term.”

As a result, 1xbet online sports betting ’s team is looking at ways to help combat neuroinflammation with omega-3 supplements.

“We are developing interventions that promote decisions that lead to health and prosperity,” 1xbet online sports betting said.

The aging 1xbet online sports betting

As we age, we naturally experience cognitive declines. We might forget where we parked our car or what we had for breakfast yesterday. But we 1xbet online sports betting gain more experience and knowledge.

Heather Bailey, assistant professor of psychological sciences, thinks that is important. She is studying how older adults 1xbet online sports betting use their experiences and knowledge to learn new information.

Her project has two groups of people — adults ages 65 to 85 and adults ages 18 to 28 — watch a series of videos that depict everyday activities, such as cooking breakfast, balancing a checkbook or working with technology. Bailey uses eye tracking technology to determine what people pay attention to and uses fMRI, which stands for functional magnetic resonance imaging, to determine what parts of the 1xbet online sports betting are involved in learning and remembering new information.

“We are finding that when people have relevant knowledge, they are better able to remember the activity in the video,” Bailey said. “However, if they don’t have any relevant knowledge, then chunking the activity into smaller events 1xbet online sports betting improve their memory.”

More than 200 1xbet online sports betting have participated in this study either on the K-State Manhattan campus or at the Hoglund 1xbet online sports betting Imaging Center with the University of Kansas Medical Center.

Bailey is planning further work with 1xbet online sports betting suffering from early onset Alzheimer’s disease or other neurodegenerative diseases.

“Our research could 1xbet online sports betting improve older adults’ quality of life and 1xbet online sports betting them function independently longer,” Bailey said.

But what happens before we age? 1xbet online sports betting our childhood environments affect our brains as adults?

That’s 1xbet online sports betting Mary Cain, professor of psychological sciences, aims to understand. She studies how childhood environments affect alcohol and drug use in adults.

Through her work with rodent models, she has found that rats raised in an enriched environment with toys and social interaction have lower drug and alcohol intake as adults. Cain 1xbet online sports betting has found that rats raised in an enriched environment are very sensitive to the taste of alcohol and sugar water.

“We know that the early rearing environment causes 1xbet online sports betting changes, but it’s really novel that it also may be altering taste,” Cain said. “That may have implications for alcohol use in adulthood as well.”

By looking at images of the 1xbet online sports betting , Cain can better understand how the structure of the 1xbet online sports betting , specifically parts of the nerves themselves, can affect alcohol use in adulthood. Her work also applies to humans.

“Our research shows that any kind of enrichment provided during childhood is protective against drug and alcohol use in adulthood, and that’s a result of plasticity changes,” Cain said. “Early life enrichment is really important.”

Comparing the 1xbet online sports betting

One of the best model species for studying the human 1xbet online sports betting is a small, 2-inch minnow: the zebrafish. That’s because about 75% of human genes also are found in zebrafish and about 84% of human disease genes have a counterpart in zebrafish.

“This shared genetic setup makes 1xbet online sports betting a fascinating model for studying human affective disorders and the neural basis of affection, emotion and cognition,” said Thomas Mueller, research assistant professor in the Division of 1xbet be.

Specifically, Mueller studies the amygdala, which is the part of the human and fish 1xbet online sports betting that controls emotion and mediates social behavior and associative emotional learning, such as fear learning. Mueller focuses on two neurological disorders that are affected by the amygdala: autism spectrum disorders and post-traumatic stress disorder.

“We like to think that only humans and maybe our pets have emotions,” Mueller said. “But my research shows that the neurocircuits and the amygdala of the zebrafish are not only very complex, but also stunningly similar to the mammalian 1xbet online sports betting , much more similar, in fact, than previously imagined.”

1xbet online sports betting ’s research group is now using a CNAP pilot grant and part of a .3 million 1xbet online sports betting Frontier Research Foundation grant for an international collaboration to better understand how spatial and associative learning are organized in 1xbet online sports betting and other fish.

Imaging the 1xbet online sports betting

But important functional and anatomical 1xbet online sports betting research is only as good as the images you can capture.

In fact, CNAP has fostered collaboration in 1xbet online sports betting imaging technologies. As part of the center’s mission, Mueller and Cain are working with Stefan Bossmann, university distinguished professor of Welcome to. Bossmann’s team specializes in state-of-the-art 1xbet online sports betting of neurons using a National Science Foundation-funded instrument called an fMRI, which analyzes chemical compounds in the 1xbet online sports betting .

The partnership 1xbet online sports betting involves Punit Prakash, the Paul L. Spainhour professor in the Mike Wiegers Department of Electrical and 1xbet online sports betting Engineering, who is creating better ways to evaluate the 1xbet online sports betting and data.

Bossmann uses a 600-megahertz MRI to capture incredibly detailed images — around 100 micrometers in resolution — of the zebrafish and rodent brains to show what parts of the 1xbet online sports betting are activated in specific situations. The technique is called diffusion tensor imaging, or DTI, and measures the signaling between neurons. The technique also can benefit people with diseases such as multiple sclerosis because it can determine what neurons are or are not working.

“This kind of functional imaging is very rarely done, and 1xbet online sports betting is not done to the resolution that we have,” Bossmann said.

The high-resolution MRI images allow Mueller to create data-rich 3D functional atlases of zebrafish brains. Cain uses the images to study how substances in the 1xbet online sports betting , specifically myelin, may increase resistance to alcohol abuse.

Bossmann, who 1xbet online sports betting works with the K-State Johnson Cancer Research Center and the Center of Excellence for Pancreatic Cancer Research, uses MRI for tumor research. 1xbet online sports betting was natural for Bossmann to get involved with CNAP, too.

“I am able to collaborate with the team to develop new methodologies and make them available to the community,” Bossmann said. “The research 1xbet online sports betting give important insight into therapeutic targets.”

Training the 1xbet online sports betting

As our brains process sights and sounds, CNAP scientists use EEG to show neural activity as it is happening. With EEG, short for electroencephalography, participants wear a special cap with noninvasive electrodes that detect electrical activity in the 1xbet online sports betting .

Matthew Wisniewski, assistant professor of psychological sciences, and Alexandria Zakrzewski, research assistant professor of psychological sciences, are developing new EEG facilities to study how our brains process 1xbet online sports betting we see and 1xbet online sports betting we hear.

Wisniewski studies auditory learning and his work aims to train people to hear new details in sound. For his projects, people wear an EEG cap while they are in a sound booth listening to sounds through earphones. The EEG provides a measurement of how the 1xbet online sports betting reacts to sound before and after training exercises, as well as the extent to which individuals put effort into listening.

“We’re measuring their ability to hear details in sound over the course of training,” Wisniewski said. “We want to know what types of training are most effective for changing the 1xbet online sports betting and improving listening performance. These procedures can then be used to train listening skills with hearing aids or cochlear implants.”

Zakrzewski’s research focuses on metacognition, which is how we think about our own thinking. Her work 1xbet online sports betting help people who are struggling with addiction or who might have poor cognitive ability and not know they are struggling.

“Metacognition is really useful for how we might monitor our judgments and control our behavior,” said Zakrzewski, who 1xbet online sports betting leads the EEG facility. “I’m interested in metacognitive accuracy, or how well we know when we’re right or wrong.”

Zakrzewski has participants make confidence ratings during perceptual or memory tasks and uses EEG imaging techniques to capture metacognition in the 1xbet online sports betting . She is building training programs to help people improve their metacognitive abilities so they can change or adjust their behaviors.

Informing the 1xbet online sports betting

The research generated from the large amounts of EEG data and high-resolution images of the 1xbet online sports betting requires a lot of computer power.

Enter Beocat, the high-performance computing cluster at K-State. Beocat is the most powerful supercomputer in Kansas and is 4,000 times more powerful 1xbet online sports betting the average laptop.

“Research is becoming dominated by big data and interdisciplinary teams, and CNAP is a model for this type of interaction,” said Dan Andresen, professor of 1xbet online sports betting science and director of the Institute for Computational Research. “You 1xbet online sports betting have the best ideas and the best researchers, but they aren’t going to get their research done unless they have an environment that 1xbet online sports betting handle it.”

Beocat’s large processing capacity already has made a difference for CNAP research: Data analysis that used to take days 1xbet online sports betting now be done in hours. Researchers 1xbet online sports betting easily crunch numbers and transfer data to collaborators.

K-State computer scientists are developing 1xbet online sports betting analytic methods for the massive amounts of data and images that CNAP researchers collect. Computer science graduate and undergraduate students often partner with the psychological sciences and biology researchers to develop 1xbet online sports betting programs that work quickly and efficiently.

“1xbet online sports betting is a great experience for these computer science students because they are taken out of their engineering bubble and get interdisciplinary real-world experience,” Andresen said. “Science is becoming more digitized and more data dependent. That’s where we come in.”