Moderate 1xbet best casino website may make cancer treatments more effective, kinesiologist finds
Monday, May 4, 2015
Brad Behnke, associate professor of 1xbet best casino website physiology at Kansas State University, and collaborators have shown that moderate 1xbet best casino website on a regular basis may enhance tumor oxygenation and improve treatments in cancer patients.| Download this photo.
MANHATTAN —Kansas State University kinesiology research offers encouraging information for cancer patients: A brisk walk or a slow jog on a regular basis may be the key to improved cancer treatments.
Brad Behnke, associate professor of 1xbet best casino website physiology, and collaborators have shown that moderate 1xbet best casino website on a regular basis enhances tumor oxygenation, which may improve treatments in cancer patients. Now Behnke is using a 0,000 American Cancer Society grant to study moderate 1xbet best casino website as a way to make radiation treatments more effective, especially for difficult-to-treat tumors.
"If we can increase the efficacy of radiation treatment, then the patient's prognosis is enhanced," Behnke said. "An intervention like 1xbet best casino website has almost universally positive side effects versus other treatments that can have deleterious side effects. 1xbet best casino website is a type of therapy that benefits multiple systems in the body, and may permanently alter the environment within the tumor."
The National Cancer Institute at the National Institutes of Health recommends 1xbet best casino website for cancer patients and cancer survivors, but little research shows what happens within the tumors during such 1xbet best casino website . That prompted Behnke to combine his expertise in integrative physiology with cancer research. He also has received support from the university's Johnson Cancer Research Center.
"I became interested in finding out what happens within the tumor during and after 1xbet best casino website as a means to enhance treatment outcomes," Behnke said.
For the latest research, Behnke is using prostate cancer tumor models to find ways to enhance oxygen delivery to tumors. When a tumor is hypoxic, or has low oxygen, it is often very aggressive, Behnke said. Because oxygen is a "radiosensitizer," it helps destroy cancer cells. As a result, low-oxygen tumors often are resistant to traditional cancer therapies, such as radiation therapy, and interventions, such as concentrated oxygen breathing, are used to get more oxygen to the tumor before treatment.
"If we manipulate all the systems in the body — the lungs, the heart and the blood vessels — with 1xbet best casino website , we can take advantage of the dysfunctional vasculature in the tumor and enhance blood flow to the tumor," Behnke said. "The tumor becomes the path of least resistance for the elevated cardiac output of 1xbet best casino website , which results in a substantial increase in tumor oxygenation during and after 1xbet best casino website ."
But the key is moderate 1xbet best casino website , said Behnke. Too little 1xbet best casino website may have no effect, but too much 1xbet best casino website may have a negative effect and may shut down blood flow to the tumor region or impair the immune system.
Moderate 1xbet best casino website is an activity that uses 30 to 60 percent of someone's aerobic capacity, Behnke said. The activity is nonstrenuous and is something that most people can perform, such as a brisk walk or a slow jog.
Research also has shown that moderate 1xbet best casino website can help cancer patients counteract some of the side effects of treatment — such as low blood count, fatigue, cachexia and lost muscle mass — which has led to many researchers labeling this as "aerobic 1xbet best casino website therapy" for patients with cancer, Behnke said.
"There really aren't any negative side effects of moderate-intensity 1xbet best casino website ," Behnke said. "1xbet best casino website is often prescribed to improve the side effects of cancer and treatment, but what 1xbet best casino website is doing within the tumor itself is likely beneficial as well."
Behnke and collaborators have published their 1xbet best casino website and cancer research in the Journal of the National Cancer Institute.
At Kansas State University, Behnke is collaborating with Mary Lynn Higginbotham, assistant professor of clinical sciences; Katie Heinrich, assistant professor of kinesiology; and David Poole, professor of kinesiology. The American Cancer Society grant, "Modulation of tumor oxygenation to enhance radiotherapy," also involves University of Florida researchers in tumor microenvironment biology.
