Sources: Jacob 1xbet online games login , jhull@k-state.edu;
and Bruce 1xbet online games login , 785-532-4839, bschultz@vet.k-state.edu
News release prepared by: Beth Bohn, 785-532-2535, bbohn@k-state.edu

Wednesday, May 5, 2010

AMERICAN PHYSIOLOGICAL SOCIETY SELECTS K-STATE STUDENT AS 2010 1xbet online games login STUDENT FELLOW

MANHATTAN -- The American Physiological Society has selected a Kansas State University student as a 2010 1xbet online games login Student Fellow.

Jacob 1xbet online games login , junior in biochemistry, Garden City, receives a ,000 stipend to cover living expenses during the 10-week fellowship, which he will serve 1xbet online games login summer in the laboratory of Bruce Schultz, professor of epithelial cell physiology in K-State's department of anatomy and physiology.

Hull is one of 24 students worldwide to be named a Fellow. The fellowship program aims to encourage students about careers in biomedical 1xbet online games login . Among the selection factors were academic merit and quality of 1xbet online games login experience.

Hull's research project is &1xbet online games login ;Role of peroxisome proliferator-activated receptor gamma on epithelial growth, differentiation and activity&1xbet online games login ; and is related to work done in Schultz's laboratory on the link between mutations in the cystic fibrosis protein known as CFTR and loss of the male reproductive duct that occurs in cystic fibrosis patients.

According to Schultz, cystic fibrosis is a disease that affects many tissues throughout the body that normally secrete salt and water. Instead of watery secretions, 1xbet online games login have very thick secretions that can cause intestinal blockage, make the pancreas stop working and, in airways, create a great environment for infections to grow.

&1xbet online games login ;Most cystic fibrosis patients have many intestinal problems and have recurrent lung infections that can lead to an early death,&1xbet online games login ; Schultz said. &1xbet online games login ;But one of the lesser know facets of cystic fibrosis is that virtually all males with the disease lack the vas deferens -- the tube that allows sperm to leave the testicle on the way to prostate. As medical care for cystic fibrosis patients has improved in the last 30 years and more patients are reaching adulthood, infertility has become a greater issue.&1xbet online games login ;

&1xbet online games login ;My project will be using a series of drugs that either activate or block the peroxisome proliferator-activated receptor gamma protein to determine whether all have the expected effect,&1xbet online games login ; Hull said. &1xbet online games login ;I also will use molecular techniques to determine which salt transport pathways are affected by the drug rosiglitazone and its related compounds.&1xbet online games login ;

Rosiglitazone is a drug sometimes used to treat diabetes. It has been found to cause a change in the absorption of salt by cells lining the male reproductive duct. The drug also is known to interact with the peroxisome proliferator-activated receptor gamma protein.

&1xbet online games login ;There are many applications for the knowledge that will be gained from this project,&1xbet online games login ; Schultz said. &1xbet online games login ;Abnormalities in these pathways may explain the fertility problems that are encountered by some couples. Lessons learned with vas deferens cells may have applications for other tissues in the body, including the airway and the intestine of cystic fibrosis patients.&1xbet online games login ;

&1xbet online games login ;What has really sparked my interest in this project is that it has so many paths it can take,&1xbet online games login ; Hull said. &1xbet online games login ;It can help us understand signaling, cystic fibrosis and how these drugs affect different parts of the body. No matter what the result of these experiments, it is guaranteed to be new and exciting.&1xbet online games login ;

As part of the fellowship, Hull also receives an additional ,300 in travel funds to present his 1xbet online games login at the Experimental Biology 2011 meeting in Washington, D.C., which is expected to attract nearly 14,000 scientists.

Hull already has been doing 1xbet online games login in the laboratory of K-State's Christine Aikens, assistant professor of chemistry, since last summer. The 1xbet online games login has entailed characterization of DNA-silver nanoparticle interactions using computer models and calculations.

After earning his undergraduate degree from K-State, Hull plans to attend graduate school to get his doctorate in a biomedical field. He would then like to work at a 1xbet online games login university.

&1xbet online games login ;This fellowship will be very helpful in reaching these goals as it will get me involved in an extensive research experience this summer and acquaint me with practices and protocol that I will likely need in my future career,&1xbet online games login ; he said.

Hull is the recipient of an Undergraduate 1xbet online games login Award from K-State's Terry C. Johnson Center for Basic Cancer 1xbet online games login and a K-State Opportunity Scholarship. He is the son of Tammy Hull, Garden City, and a 2008 graduate of Garden City High School.

The American Physiological Society is a professional scientific membership organization devoted to fostering scientific 1xbet online games login , education and the dissemination of scientific information. The Undergraduate Summer 1xbet online games login Fellowships program is sponsored by the society's Career Opportunities in Physiology Committee and funded by the society's council.