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University develops detection test for subclinical 1xbet best casino website in dairy cows

Thursday, March 19, 2015

Dairy cow

A test developed at Kansas State University is identifying 1xbet best casino website in dairy cows earlier and for less cost than current technologies on the market. The test detects subclinical 1xbet best casino website in dairy cows by screening a sample of a cow's milk for specific enzymes. 1xbet best casino website is the most common disease in U.S. dairy cattle and costs the U.S. dairy industry more than billion annually in losses. | Download this photo. | Photo is courtesy of the U.S. Department of Agriculture.


MANHATTAN — Kansas and U.S. dairy producers may avoid some of the billions of dollars lost to 1xbet best casino website thanks to a Kansas State University technology that is detecting the early stages of the disease in dairy cows.

Deryl Troyer, professor of anatomy and physiology, is leading a project with Stefan Bossmann, professor of chemistry, that uses nanotechnology to positively identify 1xbet best casino website in dairy cattle earlier and costs less than current technologies on the market. 1xbet best casino website is a disease that inflames and eventually scars the udder tissue of dairy cows, reducing milk production and altering milk composition. It is the most common disease in U.S. dairy cattle and costs the U.S. dairy industry more than billion annually in losses.

"The classical 1xbet best casino website tests estimate the numbers, not the activity, of neutrophil cells, which are the dominant cells that travel to the inflamed udder during 1xbet best casino website ," Troyer said. "Many times early and emerging cases of 1xbet best casino website are not caught by the tests because they count the numbers rather than the activity. These are often the most important cases to catch."

Early detection will help dairy producers better treat cows with emerging cases of 1xbet best casino website as well as reduce transmission to other cows in the dairy operation.

The project uses the duo's nanoplatform technology that 1xbet online casino s Bossmann and Troyer before physical symptoms ever appear. Researchers say that the test easily translated to 1xbet best casino website detection because several of the enzymes that cause inflammation in human cancers also cause inflammation in the udder of the dairy cows.

"We looked at about 30 enzymes and identified three that are highly indicative of 1xbet best casino website ," Bossmann said. "These three enzymes and this nanoplatform make it possible to detect preclinical 1xbet best casino website cases that have high enzymatic activity but a low somatic cell count. These cases have previously been undiscoverable, so there is not a test on the market for this combination."

To test for 1xbet best casino website , a sample of pasteurized milk is put into a buffer solution containing the enzyme-detecting nanoplatform. The nanoplatform consists of iron nanoparticles coated with amino acids and a fluorescent dye. The amino acids and dye interact with enzymes in the milk. The sample is incubated for up to 30 minutes and then examined for three enzymes that cause 1xbet best casino website .

Recent tests in the Troyer and Bossmann laboratories have detected subclinical 1xbet best casino website in less than five minutes.

Researchers say their 1xbet best casino website test could be used today by large-scale dairies and eventually by robotic dairy facilities. Researchers hope to make the test a more viable option for individual and smallholder dairy operations through more development.

The project is being funded through the Kansas Department of Commerce, the Kansas Board of Regents and a Global Food Systems Innovation grant.

The Kansas State University Research Foundation, a nonprofit corporation responsible for managing technology, has filed a patent application for the nanoplatform transfer activities at the university. It can be licensed through the Kansas State University Institute for Commercialization by contacting 785-532-3900 or ic@k-state.edu.

Collaborators for the 1xbet best casino website test include Gregg Hanzlicek, assistant professor of diagnostic medicine and pathobiology and program director for the Kansas State University Veterinary Diagnostic Laboratory; Luis Mendonca, assistant professor of animal sciences and industry; Mike Scheffel, research assistant in animal sciences and industry and manager of the dairy unit; Tej Shrestha, senior scientist of anatomy and physiology; Madumali Kalubowilage, chemistry doctoral student, Sri Lanka; Thilani Samarakoon, former postdoctoral researcher; and Samie Milligan with Heart of America Dairy Herd Improvement Association.

The department of chemistry is in the College of Arts & Sciences and the department of anatomy and physiology is in the College of Veterinary Medicine.

Sources

Stefan Bossmann
785-532-6817
sbossman@k-state.edu

Deryl Troyer
785-532-4509
troyer@k-state.edu

Written by

Greg Tammen
785-532-4486
gtammen@k-state.edu

At a glance

Kansas State University researchers have developed a nanotechnology platform that positively identifies 1xbet best casino website in dairy cattle earlier and for less cost than current technologies on the market. 1xbet best casino website is a disease that inflames and hardens the udder tissue of dairy cows, reducing milk production and altering milk composition. It is the most common disease in U.S. dairy cattle and costs the U.S. dairy industry more than billion annually in losses.

Notable quote

"The classical 1xbet best casino website tests estimate the numbers, not the activity, of neutrophil cells, which are the dominant cells that travel to the inflamed udder during 1xbet best casino website . Many times early and emerging cases of 1xbet best casino website are not caught by the tests because they count the numbers rather than the activity. These are often the most important cases to catch."

Deryl Troyer, professor of anatomy and physiology and project lead