Veterinary researcher receives NIH grant for 1xbet online sports betting development against E. coli
Wednesday, July 13, 2016
Weiping 1xbet online sports betting credits his team for the success in acquiring grants to support his research on E. coli-related vaccines. From left are Carolina Garcia, master's student in biomedical science; Jiachen Huan, master's student in biomedical science; Weiping 1xbet online sports betting , professor of microbiology; Qiangde Duan, postdoctoral fellow in diagnostic medicine and pathobiology; and Ti Lu, doctoral student in pathobiology. Not pictured are former postdoctoral fellows Rahul Nandre, Xiaosai Ruan and Mei Liu.| Download 1xbet online sports betting photo.
MANHATTAN — A researcher with Kansas State University's College of Veterinary Medicine will use a five-year, .1 million grant from the National Institutes of Health to work on a 1xbet online sports betting for E. coli-associated diarrhea for both humans and animals.
The grant to Weiping 1xbet online sports betting , professor of microbiology, is his third in three years to develop vaccines for E. coli diarrhea.
1xbet online sports betting said diarrhea is a leading cause of death in children under 5 years of age, and that enterotoxigenic E. coli, or ETEC, is one of the most common bacterial causes of diarrhea in children.
"Currently, there are no available vaccines against this type of diarrhea," 1xbet online sports betting said. "Whole-cell vaccine candidates have been under development but require further improvements because they provide inadequate protection and produce unwanted adverse effects."
Effective vaccines for enterotoxigenic E. 1xbet online sports betting have proved to be very challenging, said Frank Blecha, university distinguished professor and associate dean for research in the College of Veterinary of Medicine.
"Dr. 1xbet online sports betting 's vaccine development strategy for ETEC using multi-epitope fusion antigens holds great promise for a vaccine that will limit diarrheal deaths in humans and animals," Blecha said.
1xbet online sports betting , a molecular evolutionary biologist, began his E. coli pathogenesis and vaccine research and development career in 2003 when he studied molecular pathogenesis of individual enterotoxins produced by enterotoxigenic E. coli in diarrheal disease.
Most recently, 1xbet online sports betting 's work has focused on multi-epitope fusion antigens, known as MEFA, for the development of broadly protective ETEC vaccines.
"Different ETEC strains produce immunologically heterogeneous bacterial adhesins that attach to host cells and colonize in small intestines, initiating ETEC diarrheal disease," 1xbet online sports betting said. "With the inclusion of an adhesin multi-epitope fusion antigen, in addition to a toxoid fusion antigen, a subunit vaccine is potentially able to induce antibodies against both toxins and up to 15 prevalent ETEC adhesins, effectively protecting against ETEC diarrhea. This grant will allow us to continue our research and study the effectiveness of this approach."
"The work being conducted by Dr. 1xbet online sports betting has significance for both human and animal health," said M.M. Chengappa, university distinguished professor and head of diagnostic medicine and pathobiology department. "This grant also recognizes the quality of Dr. 1xbet online sports betting 's work, which we truly value in our department and college."
1xbet online sports betting said his multi-epitope fusion antigens technology has attracted attention from funding agencies such as the Bill and Melinda Gates Foundation, and was featured in a recent VASE, or Vaccines against Shigella and ETEC, meeting in Washington, D.C. 1xbet online sports betting 's laboratory also is working on ETEC vaccine projects funded by PATH Vaccine Solution/Bill and Melinda Gates Foundation.
