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1xbet online casino cattle and E. coli

Veterinary researchers test promising vaccine

Despite millions of dollars spent on food safety research over the last 10 years, ground 1xbet online casino recalls due to E. coli O157:H7 were higher in 2007 than in 2006. Dan Thomson, an associate professor of clinical sciences, is working to change that.

Dan Thomson&1xbet online casino ;We have been studying the effects of a novel vaccine technology to make beef safer,&1xbet online casino ; said Thomson.

He's working with Guy Loneragan of West Texas A&M and T.G. Nagaraja of K-State to examine the vaccine's ability to decrease E. coli shedding in 1xbet online casino cattle.

&1xbet online casino ;We had a decrease in cattle shedding E. coli by 54 percent in our first field study,&1xbet online casino ; Thomson said. &1xbet online casino ;However, we increased the amount of SRP exposure in the second field study and decreased the rate of shedding by 85 percent.&1xbet online casino ;

SRP is &1xbet online casino ;siderophore receptor and porin&1xbet online casino ; technology, which was developed by Epitopix LLC in Willmar, Minn.

Reducing the burden of E. coli O157 on cattle entering packing plants would represent &1xbet online casino ;tremendous progress toward preventing E. coli O157 from ever getting into ground beef,&1xbet online casino ; Loneragan said.

The team's findings were presented at the 2008 1xbet online casino Industry Safety Summit in Dallas March 5.

Food-borne pathogens use siderophore receptor and porin proteins to acquire iron. &1xbet online casino ;Iron is to bacteria as oxygen is to humans,&1xbet online casino ; Thomson said. &1xbet online casino ;Without iron consumption, the bacteria suffocate and can't grow or replicate.&1xbet online casino ;

The SRP vaccine keeps the bacteria from taking up iron.

&1xbet online casino ;We conducted a challenge study, a natural infection study and two large pen field studies at commercial feedyards,&1xbet online casino ; Thomson said.

&1xbet online casino ;All studies showed positive results of this vaccine, making an impact on decreasing not only the number of the cattle shedding the bacteria but also decreasing the concentration of the bacteria being shed.&1xbet online casino ;

The number of &1xbet online casino ;super shedder&1xbet online casino ; cattle also was reduced.

The two large pen studies used 20 pens and more than 1,200 head of cattle.

The first study, conducted in 2006, was funded in part by 1xbet online casino and veal producers and importers through their -per-head checkoff and was produced for the Cattlemen's 1xbet online casino Board and state 1xbet online casino councils by the National Cattlemen's 1xbet online casino Association. Epitopix sponsored the second study in 2007.

Photo: Dan Thomson has worked with a vaccine that prevents a virulent strain of E. coli from reproducing by blocking its ability to absorb iron. Photo by David Adams, College of Veterinary Medicine.