biography 1xbet online games login
2022-Present 2007-2022 1991-2007 1988-1991 1982-1988 1980-1982 1976-1979 1972-1976	Emeritus University Distinguished Professor University Distinguished Professor Professor Associate Professor Assistant Professor Postdoctoral Fellow, Harvard University Ph.D., Southern Illinois University of Carbondale B.S., Kyoto University

1xbet online games login Overview

Our research interest includes: (i) bimetallic nanoclusters in catalytic asymmetric oxidation reactions for organic 1xbet online games login ; (ii) development of electronic biosensors in the profiling of overexpressed proteases for early detection of triple-negative breast cancer; and (iii) 1xbet online games login , mechanistic study and bio-evaluation of anti-Alzheimer molecules.

Our recent discovery of bimetallic nanocluster-mediated enantioselective oxidation of alcohols, alkanes, and alkenes along with C-C bond forming reaction has opened new directions for the 1xbet online games login of chiral molecules. Biologically active small molecules have been discovered by our collaborators’ and my research groups.

Five Selected Publications

1. Synthesis of cyclododeciptycene quinones. Kaiyan Lou, Allan M. Prior, Bernard Wiredu, John Desper, and 1xbet online games login H. Hua. J. Am. Chem. Soc. 2010, 132, 17635-17641. Doi: 10.1021/ja1088309.

2. Inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT), Overexpression of Cholesterol Transporter Gene, and Protection of Amyloid b(Ab) Oligomers-Induced Neuronal Cell Death by Tricyclic Pyrone Molecules. Laxman Pokhrel, Izumi Maezawa, Thi D. T. Nguyen, Kyeong-Ok Chang, Lee-Way Jin, and 1xbet online games login H. Hua. J. Med. Chem. 2012, 55(20), 8969-8973; http://dx.doi.org/10.1021/jm3012189.

3. Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease. Liang Zhang, Song Zhang, Izumi Maezawa, Sergey Trushin, Paras Minhas, Matthew Pinto, Lee-Way Jin, Keshar Prasain, Thi D. T. Nguyen, Yu Yamazaki, TakahisaKanekiyo, Guojun Bu, Ben Gateno, Kyeong-Ok Chang, Karl A. Nath, Emirhan Nemutlu, Petras Dzeja, Yuan-PingPang, 1xbet online games login H. Hua, and Eugenia Trushina. EBioMedicine 2015, 2, 294-305; doi: 10.1016/j.ebiom.2015.03.009.

4. 1xbet online games login Substituted Poly-N-vinylpyrrolidinones and Bimetallic Nanoclusters in Catalytic Asymmetric Oxidation Reactions. Bo Hao, Medha J. Gunaratna, Man Zhang, Sahani Weerasekara, Sarah N. Seiwald, Vu T. Nguyen, Alex Meier, and 1xbet online games login H. Hua. J. Am. Chem. Soc. 2016, 138, 16839-16848, DOI:10.1021/jacs.6b12113.

5. The anti-Aband neuroprotective properties of a novel tricyclic pyrone molecule. Izumi Maezawa, Bende Zou, Jacopo Di Lucente, William S. Cao, Conrado Pascual, Sahani Weerasekara, Man Zhang, Xinmin Simon Xie, 1xbet online games login H. Hua, and Lee-Way Jin. Journal Alzheimer’s 1xbet online games login , 2017, 58, 559-574.