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1xbet online sports betting . Juergen A. Richt, Regents and University Distinguished Professor at Kansas State University and Director of the Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD, www.ceezad.org) and the Center on Emerging 1xbet online sports betting (CEZID; Our 1xbe), was interviewed recently by K-1xbet online sports betting President Richard Linton about the important work being done in his lab.
You 1xbet online sports betting see and hear the full interview by watching the video below.
Next-Gen 'Cats: Click the image to learn more about K-1xbet online sports betting research improving the lives of Kansans.
December 19, 2023
Board of Regents extends 1xbet online sports betting . Richt’s designation as Regents Distinguished Professor on December 19, 2023
The Kansas Board of Regents has unanimously approved a request by Kansas State University (KSU) to extend recognition of 1xbet online sports betting . Juergen A. Richt as the Regents Distinguished Professor at KSU. Such extensions are confirmed every five years. The action took place at a recent meeting of the Kansas Board of Regents. 1xbet online sports betting was reported recently by the Manhattan Mercury on Page A1 | e-Edition | themercury.com.
1xbet online sports betting . Richt is Director of the Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD; www.ceezad.org) and the Center on Emerging 1xbet online sports betting (CEZID; Our 1xbe), both located at KSU. 1xbet online sports betting is regarded as a pioneer in the field of veterinary science.
In confirming the decision, 1xbet online sports betting cited the Board of Regents Vice Chair Mr. Carl Ice quoting a committee 1xbet online sports betting as saying, “he seems like the very type of professor we would want to get 1xbet online sports betting distinction.”
1xbet online sports betting . Richt expressed gratitude for the confidence expressed by the Kansas Board of Regents in unanimously determining to continue his designation as the Regents Distinguished Professor at KSU: “I am humbled by the Kansas Board of Regents support for my 1xbet online sports betting . I will wholeheartedly continue to pursue advances in the field of veterinary research with unwavering vigor,” 1xbet online sports betting said.
April 1, 2022
Yale bacteriologist is featured in CEZID 1xbet online sports betting on April 1, 2022
A world-renowned bacteriologist discussed his laboratory’s research on different types of Salmonella as the April speaker on the Center on Emerging 1xbet online sports betting (CEZID; www.k-1xbet online sports betting edu) Distinguished Speaker series. 1xbet online sports betting was the first in-person seminar of 1xbet online sports betting Speaker Series, and was also available online.
The speaker was 1xbet online sports betting . Jorge Galán , a professor of Microbial Pathogenesis and Cell Biology and Chair of the Department of Microbial Pathogenesis at the Yale University School of Medicine. On the Yale faculty since 1998, he is a member of the National Academy of Sciences and the National Academy of Medicine. The title of his presentation was “Pathogen Restriction and Host Specificity: Insights From the Human Pathogen Salmonella Typhi”.
1xbet online sports betting . Galan discussed his laboratory’s work on Salmonella typhi, the cause of typhoid fever in humans. In particular, 1xbet online sports betting . Galán's presentation focused on the mechanisms behind the strict host specificity exhibited by Salmonella Typhi, which can only infect humans. There are many different types of Salmonella, some of which can infect many different hosts, and therefore can gain access to the food chain and eventually infect humans. Others, like Salmonella typhi, are specifically adapted to a single host.
1xbet online sports betting . Galán’s presentation elaborated on the multiple mechanisms that have led to Salmonella Typhi to become adapted to the human host.
1xbet online sports betting . Meng speaks on Hepatitis E virus research as part of CEZID Distinguished Speaker Series
1xbet online sports betting . X. J. Meng, University Distinguished Professor and Director of the Virginia Tech Center for Emerging, Zoonotic and Arthropod-borne Pathogens (CeZAP), delivered a presentation on Oct. 22 concerning his work on Hepatitis E virus as part of the Distinguished Speaker series of the Center on Emerging and Zoonotic Infectious Diseases (www.cezid.org) at Kansas State 1xbet online sports betting .
1xbet online sports betting . Meng is an elected member of the National Academy of Sciences, an elected fellow of the American Academy of Microbiology, and an elected fellow of the National Academy of Inventors. He received his medical degree from Binzhou Medical University in China, a master's degree from Wuhan University and a doctorate from Iowa State University. From 1995 to 1999, Meng was a John Fogarty visiting scientist and later a senior staff fellow at NIAID, NIH, Bethesda, Maryland.
Hepatitis E virus is a single-stranded, positive-sense, small RNA virus infecting both humans and more than a dozen other animals. In his presentation, 1xbet online sports betting . Meng said Hepatitis E virus causes about 20 million human infections annually, with 44,000 deaths worldwide.
It 1xbet online sports betting also be found in numerous animal species, among them pigs, camels, deer, rabbits, rats, chickens, moose and ferrets.
1xbet online sports betting . Meng discussed his experiments on cross-species infection of non-human primates with swine HEV. He also discussed cross-species infections of pigs with human HEV.
Much of 1xbet online sports betting presentation focused on modes of infection of humans, notably foodborne hepatitis E virus infection by consumption of contaminated animal meat products or zoonotic infection via contact with infected animals.
He also discussed 1xbet online sports betting lab’s research findings regarding genetic, and environmental reasons behind cross-species hepatitis E virus infection.
CEZID effort includes 1xbet online sports betting new research core facilities
Researchers from the Center on Emerging 1xbet online sports betting , CEZID, (www.cezid.org) have established two new core facilities designed to enhance research into zoonotic 1xbet online sports betting diseases.
CEZID, a National Institutes of Health (NIH)-sponsored organization committed to biomedical research excellence, is directed by 1xbet online sports betting . Juergen A. Richt, the Regents Distinguished Professor at Kansas State University and an internationally recognized virologist. 1xbet online sports betting . Phil Hardwidge, an internationally recognized bacteriologist, of Kansas State University’s College of Veterinary Medicine, is the associate director.
The two newly established core facilities are an animal 1xbet online sports betting /pathology (AMP) core and a molecular and cellular biology (MCB) core.
The AMP core provides personalized, project-specific support and expertise to facilitate the use of animal models and pathology services. Existing infrastructure includes a new laser capture micro-dissection instrument. The AMP core 1xbet online sports betting also produce hybridomas and hyper-immune sera for the development of diagnostic tests essential to Centers of Biomedical Research Excellence (COBRE) research.
The MCB Core 1xbet online sports betting provide imaging and flow cytometry services to COBRE users. MCB Core services include DNA sequencing, CRISPR technology, and cell-sorting capabilities. MCB Core support for bioinformatics and handling of large DNA sequencing datasets is also provided.
The MCB Core offers 1xbet online sports betting equipment including a NextSeq, BD FACSMelody Cell Sorter Live Cell Imager equipment, and several machines for single-cell gene expression analysis.
NIH-backed CEZID researchers probing zoonotic 1xbet online sports betting diseases
Since its inception in 2020, researchers from the Center on Emerging 1xbet online sports betting (www.cezid.org) have advanced several areas of research into zoonotic 1xbet online sports betting diseases.
CEZID, a National Institutes of Health (NIH)-sponsored organization committed to biomedical research excellence, is directed by 1xbet online sports betting . Juergen A. Richt, the Regents Distinguished Professor at Kansas State University and an internationally recognized virologist. 1xbet online sports betting . Phil Hardwidge, an internationally recognized bacteriologist, of Kansas State University’s College of Veterinary Medicine, is the associate director.
Here’s a brief synopsis of the four 1xbet online sports betting -backed research projects currently underway through CEZID.
- Mechanisms of effector-mediated host defense using Legionella, 1xbet online sports betting . Stephanie Shames, College of Arts and Science, Kansas State University
Emerging 1xbet online sports betting cause global health devastation and are increasing in prevalence due to human activity and other factors that facilitate disease spread. Often, the etiological agents of EZIDs are difficult to study due to lack of established tools and genetic systems to perform hypothesis-driven research. The objective of this work is to use bacteria of the genus Legionella as model 1xbet online sports betting to characterize host defense mechanisms applicable to EZIDs. Legionella species are natural 1xbet online sports betting of protozoa and accidental human 1xbet online sports betting that can cause disease upon inhalation of contaminated aerosols and subsequent bacterial replication within alveolar macrophages. The overall objective is to elucidate mechanisms by which effector function contributes to pathogen clearance by the innate immune system and determine whether these can be used to enhance defense against other 1xbet online sports betting .
- Cutaneous human papillomavirus as a novel model of viral oncogenesis, 1xbet online sports betting . Nicholas Wallace, College of Arts and Sciences, Kansas State University
Emerging 1xbet online sports betting diseases account for at least 12% of all human pathogens. Increased globalization led the World Health Organization to predict that novel 1xbet online sports betting agents will continue to appear at an unprecedented rate. To protect society against these pathogens, it is essential to know all of the potential mechanisms by which 1xbet online sports betting agents can cause disease. While viral infections are known to cause 15-20% of cancers, persistent genus β human papillomavirus (β-HPV) infections cause non-melanoma skin cancers. β- HPV’s role in these malignancies is through a novel mechanism that could be shared with emerging pathogens. This work defines the extent that loss of the p300 protein prevents cells from mitigating genome destabilizing events, particularly events occurring during the S-phase. The overall goal of this work is to understand the mutagenic potential of p300 destabilization to improve risk assessment of emerging viruses.
- Rational design of live-attenuated vaccines for flaviviruses, 1xbet online sports betting . Yan-Jang (Scott) Huang, College of Veterinary Medicine, Kansas State University
The objective of the work is to develop broadly effective attenuation strategies for the rational design of live-attenuated vaccines (LAVs) against flaviviruses. Pathogenic flaviviruses cause severe human diseases such as hemorrhagic fever and encephalitis. The use of two legacy vaccines, yellow fever virus (YFV) 17D and Japanese encephalitis virus (JEV) SA14-14-2, has demonstrated how immunization can be an efficient strategy for disease control. However, the empirical approach used for the development of these LAVs has proven ineffective in producing candidate LAVs for other flaviviruses, thereby demanding new strategies for rational vaccine design. The central hypothesis is that conserved residues in the interdomain peptides are functionally important for flavivirus virulence, regardless of their tissue tropism and disease pathogenesis. Broadly effective attenuation strategies will be developed by engineering selected mutations into the full-length complementary DNA 1xbet online sports betting clones of two model flaviviruses, West Nile virus and YFV; then demonstrate the loss of virulence in respective mouse models. The completion of the studies will lead to an advancement in knowledge regarding the functional importance of the EDI-EDII hinge and EDI-EDIII linker interdomain regions for flavivirus virulence.
- Host and aquatic environment dependent cost and benefits of Shigella flexneri virulence plasmid and Shiga toxin production. 1xbet online sports betting . Thomas Platt, College of Arts and Sciences, Kansas State 1xbet online sports betting
Many emerging 1xbet online sports betting diseases maintain significant populations outside of host environments. The consequences of dynamics occurring in these environmental reservoirs on the pathogenesis of these pathogens is seldom investigated and poorly characterized. This project examines how the molecular systems that facultative pathogens use to exploit hosts are shaped by the consequences of dynamics occurring within both host and environmental reservoir environments. The proposed work will determine the context-dependent fitness consequences of Shigella virulence factors and determine whether selection in environmental reservoirs may contribute to the recent emergence of 1xbet online sports betting Shiga toxin producing Shigella 1xbet online sports betting .
Beyond the four research programs, CEZID is also overseeing five pilot projects, all conducted by Kansas State 1xbet online sports betting faculty. Those five are:
- Identifying novel antiviral targets to inhibit flaviviral replications using CRISPR, 1xbet online sports betting . Dana Vanlandingham
- Molecular mechanisms of tick-borne pathogen infection in the tick vector. 1xbet online sports betting . Kathryn Reif
- Establishing a rationally designed universal rotavirus reverse genetics platform, 1xbet online sports betting . Rachel Palinski
- Characterization of the impact of Salmonella SseK1 on bacterial gene regulation, 1xbet online sports betting . Samir El Qaidi
- Nanoparticle based antiviral 1xbet online sports betting SARS-CoV-2, Robert DeLong
CEZID holds its Annual Meeting
Officials of the Kansas State 1xbet online sports betting -based Center on Emerging and Zoonotic Infectious Diseases (www.cezid.org) held the 1xbet online sports betting ’s Annual Meeting Oct. 20-21 on the KSU campus.
The Center, a National Institutes of Health Center of Biomedical Research Excellence (COBRE), was established in 2020 with a focus on research projects bridging areas of excellence within the infectious disease programs of the Colleges of Veterinary Medicine and Arts and Sciences at Kansas State 1xbet online sports betting .
1xbet online sports betting . Juergen A. Richt, Regents Distinguished Professor of Veterinary Medicine at KSU, is director of CEZID. 1xbet online sports betting . Phil Hardwidge, a professor in the College of Veterinary Medicine at KSU, is assistant director.
The meeting was held at the lecture hall of the Grain Science complex 1xbet online sports betting .
Focal points of the two-day annual meeting included evaluation of projects by members of advisory committees. They reviewed the status of research by nine project leaders whose 1xbet online sports betting is being conducted under CEZID auspices. Those were:
*1xbet online sports betting . Nicholas Wallace, College of Arts and Sciences: Cutaneous human papillomavirus as a novel model of viral oncogenesis.
*1xbet online sports betting . Yan-Jang Huang, College of Veterinary Medicine: Rational design of live-attenuated vaccines for flaviviruses.
*1xbet online sports betting . Thomas Platt, College of Arts and Sciences: Host and aquatic environment dependent cost and benefits of Shigella flexneri 1xbet online sports betting plasmid and Shiga toxin production.
*1xbet online sports betting . Stephanie Shames, College of Arts and Sciences: Mechanisms of effector-mediated host defense using Legionella.
*1xbet online sports betting . Rachel Palinski, College of Veterinary Medicine: Establishing a rationally designed universal rotavirus reverse genetics platform.
*1xbet online sports betting . Kathryn Reif, College of Veterinary Medicine: Molecular mechanisms of tick-borne pathogen infection in the tick vector.
*1xbet online sports betting . Dana Vanlandingham, College of Veterinary Medicine: Identifying novel antiviral targets to inhibit flaviviral replication using CRISPR.
1xbet online sports betting . Robert Delong, College of Veterinary Medicine: Nanoparticle based antiviral against SARS-CoV-2.
1xbet online sports betting . Samir El Qaidi, College of Veterinary Medicine: Characterization of the impact of Salmonella SseK1 on bacterial gene regulation.
The annual meeting also included presentations on the Molecular and Cellular Biology Core by core director Hardwidge, and on the Animal Model/Pathology Core by core director 1xbet online sports betting . Igor Morozov. External and internal mentors took part, as did members of external and internal advisory committees.