Michal 1xbet sports betting , Ph.D.
Professor
Department Head
Contact informationOffice: 141 Chalmers Hall EducationB.S., University of Warsaw, Poland |
Research video
Areas of specialty
- Protein structure and function
- Protein folding, misfolding and aggregation
- AAA+ ATPases in cellular physiology and pathogenesis
- Molecular chaperones
- Development of novel antimicrobials
Nearly every process in a living cell is carried out by protein complexes with highly organized structure and undergoing dynamic transformations. Our research is focused on the AAA+ superfamily of 1xbet sports betting . AAA stands for "ATPases associated with a variety of cellular activities", which implies that these 1xbet sports betting use energy from ATP and perform a variety of functions. Our laboratory performs basic research oriented towards understanding molecular mechanisms underlying the biological function of AAA+ 1xbet sports betting . We use a combination of biological, biochemical and biophysical experimental approaches to study interactions between 1xbet sports betting , protein localization inside living cells, and structural changes in 1xbet sports betting and protein complexes.
Selected publications
Ranaweera, C. B., Glaza, P., Yang, T., and 1xbet sports betting , M.: “Interaction of substrate-mimicking peptides with the AAA+ ATPase ClpB from Escherichia coli”, Arch. Biochem. Biophys., 655, 12-17, 2018.
Kuczynska-Wisnik, D., Cheng, C., Ganta, R. R., and 1xbet sports betting , M.: ”Protein aggregation in Ehrlichia chaffeensis during infection of mammalian cells”, FEMS Microbiol. Lett., 364 (6): fnx059, 2017.
Zhang, T., Kedzierska-Mieszkowska, S., Liu, H., Cheng, C., Ganta, R. R. and 1xbet sports betting , M.: “Aggregate-reactivation activity of the molecular chaperone ClpB from Ehrlichia chaffeensis”, PLoS ONE 8(5): e62454, 2013.
Nagy, M., Guenther, I., Akoyev, V., Barnett, M. E., Zavodszky, M. I., Kedzierska-Mieszkowska, S. and 1xbet sports betting , M.: “Synergistic cooperation between two ClpB isoforms in aggregate reactivation”, J. Mol. Biol. 396, 697-707, 2010.
1xbet sports betting , M.: “A camel passes through the eye of a needle: protein unfolding activity of Clp ATPases”, Mol. Microbiol. 61, 1094-1100, 2006.