Stella Y. 1xbet online casino , Assistant Professor
Contact information
308 Ackert Hall
(785) 532-3446
sylee@ksu.edu
Lab website: http://www.k-state.edu/leelab
Education
Ph.D. 2000, Dalhousie University, Canada. Biology.
Area(s) of Specialization
Intracellular protein transport in health and diseases; Lysosomal storage disorders; Neuronal ceroid 1xbet online casino
1xbet online casino Focus
We are interested in intracellular protein transport in general. We have recently identified a negative regulator that modulates the COPI-mediated retrograde transportfrom Golgi to ER. Besides the fundamental research, we are also interested in understanding the mechanisms behind transport defects in diseases. Currently we are focusing on one particular type of lysosomal storage disorders, Neuronal-Ceroid 1xbet online casino .
Selected Publications
Adams, J., Feuerborn, M., Molina, J.A., Wilden, A.R., Adhikari, B., Budden, T., and S. Y. 1xbet online casino . 2019. Autophagy-lysosome pathway alterations and alpha-synuclein up-regulation in the subtype of neuronal ceroid 1xbet online casino , CLN5 disease. Sci Rep. 9: 151. doi: 10.1038/s41598-018-36379-z.
Adhikari, B., De Silva, B., Molina JA, Allen A, Peck SH, and S. Y. 1xbet online casino . 2019. Neuronal ceroid 1xbet online casino related ER membrane protein CLN8 regulates PP2A activity and ceramide levels. Biochim Biophys Acta Mol Basis Dis. 1865: 322-328.
Wilden A. R., Molina, J. A., Feuerborn, M., Boyle, D., and S. Y. 1xbet online casino . 2018. Glutamine-dependent 1xbet online casino homeostatic changes induced by starvation and 1xbet online casino inhibition. Biochim Biophys Acta. Mol Cell Res. 1865: 1356-1367.
De Silva, B., Adams, J., and S.Y. 1xbet online casino . 2015. Proteolytic processing of the neuronal ceroid 1xbet online casino related lysosomal protein CLN5. Exp. Cell Res. 338:45-53. doi: 10.1016/j.yexcr.2015.08.021.
Moharir, A., Peck, S.H., Budden, T., and S.Y. 1xbet online casino . 2013. The Role of N-Glycosylation in Folding, Trafficking, and Functionality of Lysosomal 1xbet online casino CLN5. PLoS 1xbet online casino 8(9): e74299. doi:10.1371/journal.pone.0074299.
Hsu, V. W., S.Y. 1xbet online casino , and J.S.Yang. 2009. The evolving 1xbet online casino of COPI vesicle formation. Nat. Rev. Mol. Cell Biol. 10, 360-364.
Zhang, L.*, S.Y. 1xbet online casino *, G.V. Beznoussenko, P.J. Peters, J.S. Yang, H.Y. Gilbert, A.L. Brass, S.J. Elledge, S.N. Isaacs, B. Moss, A. Mironov, and V.W. Hsu. 2009. A role for the host coatomer and KDEL receptor in early vaccinia biogenesis. Proc. Natl. Acad. Sci. USA 106: 163-168. (*equal contributions)
View the complete publication list in NCBI